Structures in Bacillus subtilis are recognized by CD14 in a lipopolysaccharide binding protein-dependent reaction

Infection and Immunity

Volumn 67, Issue 6, 1999, Pages 2964-2968

  Fan, Xiaolong ^a,d   Stelter, Felix ^a,c   Menzel, Rene ^a   Jack, Robert ^a   Spreitzer, Ingo ^b   Hartung, Thomas ^b   Schütt, Christine ^a  

^a UNIVERSITY MEDICINE GREIFSWALD   (Germany)

^b UNIVERSITY OF KONSTANZ   (Germany)

^c UNIVERSITY OF GREIFSWALD   (Germany)

^d LUND UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CD14 ANTIGEN; LIPID BINDING PROTEIN; LIPOPOLYSACCHARIDE; LIPOTEICHOIC ACID;

ANIMAL CELL; ANTIGEN RECOGNITION; ARTICLE; BACILLUS SUBTILIS; BACTERIAL CELL WALL; COMPLEX FORMATION; HUMAN; HUMAN CELL; MOLECULAR RECOGNITION; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN LIPID INTERACTION;

EID: 0033028806     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.67.6.2964-2968.1999     Document Type: Article

References (19)

1. Bufler, P., G. Stiegler, M. Schuchmann, S. Hess, C. Krüger, F. Stelter, C. Schütt, C. Eckershorn, and H. Engelmann. 1995. Soluble LPS receptor (CD14) is released via two different mechanisms from human monocytes and CD14 transfectants. Eur. J. Immunol. 25:604-610.
2. Fischer, W. 1993. Molecular analysis of lipid macroamphiphiles by hydrophobic interaction chromatography, exemplified with lipoteichoic acids. Anal. Biochem. 208:49-56.
3. Fischer, W., H. U. Koch, and R. Haas. 1983. Improved preparation of lipoteichoic acids. Eur. J. Biochem. 133:523-530.
4. Grunwald, U., X. Fan, R. S. Jack, G. Workalemahu, A. Kallies, F. Stelter, and C. S. Schütt. 1996. Monocytes can phagocytose Gram-negative bacteria by a CD14 dependent mechanism. J. Immunol. 157:4119-4125.
5. Gupta, D., T. N. Kirkland, S. Viriyakosol, and R. Dziarski. 1996. CD14 is a cell-activating receptor for bacterial peptidoglycan. J. Biol. Chem. 271: 23310-23316.
6. Jack, R. S., X. Fan, M. Bernheiden, G. Rune, M. Ehlers, A. Weber, G. Kirsch, R. Mentel, B. Fürll, M. Freudenberg, G. Schmitz, F. Stelter, and C. Schütt. 1997. Lipopolysaccharide binding protein is required to combat a murine Gram-negative infection. Nature. 389:742-745.
7. Jack, R. S., U. Grunwald, F. Stelter, G. Workalemahu and C. Schütt. 1995. Both membrane bound and soluble forms of CD14 bind to Gram-negative bacteria. Eur. J. Immunol. 25:1436-1441.
8. Janeway, C. A. 1992. The immune system evolved to discriminate infectious nonself from noninfectious self. Immunol. Today 13:11-16.
9. Kusunoki, T., E. Hailman, S. C. J. Todd, H. S. Lichenstein, and S. D. Wright. 1995. Molecules from Staphylococcus aureus that bind CD14 and stimulate innate immune responses. J. Exp. Med. 182:1673-1682.
10. Kusunoki, T., and S. D. Wright. 1996. Chemical characteristics of Staphylococcus aureus molecules that have CD14-dependent cell-stimulating activity. J. Immunol. 157:5112-5117.
11. Neumeister, B., M. Faigle, M. Sommer, U. Zähringer, F. Steher, R. Menzel, C. Schütt, and H. Northoff. 1998. Low endotoxic potential of Legionella pneumophila lipopolysaccharide due to failure of interaction with the monocyte lipopolysaccharide receptor CD14. Infect. Immun. 66:4151-4157.
12. Pugin, J., O. Heumann, A. Tomasz, V. V. Kravchenko, Y. Akamatsu, M. Nishijima, M. P. Glauser, P. S. Tobias, and R. J. Ulevitch. 1994. CD14 is a pattern recognition receptor. Immunity 1:509-516.
13. Rietschel, E. T., T. Kirikae, F. U. Schade, U. Mamat, G. Schmidt, H. Loppnow, A. J. Ulmer, U. Zähringer, U. Seydel, F. D. Padova, M. Schreier, and H. Brade. 1994. Bacterial endotoxin: molecular relationships of structure to activity and function. FASEB J. 8:217-225.
14. Schumann, R. R., S. R. Leong, G. W. Flaggs, P. W. Gray, S. D. Wright, J. C. Mathison, P. S. Tobias, and R. J. Ulevitch. 1990. Structure and function of lipopolysaccharide binding protein. Science 249:1429-1431.
15. Soell, M., E. Lett, F. Holveck, M. Schöller, D. Wachsmann, and J. P. Klein. 1995. Activation of human monocytes by streptococcal rhamnose glucose polymers is mediated by CD14 antigen, and mannan binding protein inhibits TNF-α release. J. Immunol. 154:851-860.
16. Stelter, F., M. Bernheiden, R. Menzel, R. S. Jack, S. Witt, X. Fan, M. Pfister, and C. Schütt. 1997. Mutation of amino acids 39-44 of human CD14 abrogates binding of lipopolysaccharide and Escherichia coli. Eur. J. Biochem. 243:100-109.
17. Weidemann, B., H. Brade, E. T. Rietschel, R. Dziarski, V. Bazil, S. Kusumoto, H. D. Flad, and A. J. Ulmer. 1994. Soluble peptidoglycan-induced monokine production can be blocked by anti-CD14 monoclonal antibodies and by lipid A partial structures. Infect. Immun. 62:4709-4715.
18. Weidemann, B., J. Schletter, R. Dziarski, S. Kusumoto, F. Stelter, E. T. Rietschel, H. D. Had, and A. J. Ulmer. 1997. Specific binding of soluble peptidoglycan and muramyldipeptide to CD14 on human monocytes. Infect. Immun. 65:858-864.
19. Wright, S. D., R. A. Ramos, P. S. Tobias, R. J. Ulevitch, and J. C. Mathison. 1990. CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. Science 249:1431-1433.