-
1
-
-
0034916581
-
Prion diseases of humans and animals: Their causes and molecular basis
-
Collinge, J. (2001) Prion diseases of humans and animals: their causes and molecular basis. Annu. Rev. Neurosci. 24, 519-550
-
(2001)
Annu. Rev. Neurosci.
, vol.24
, pp. 519-550
-
-
Collinge, J.1
-
3
-
-
0032076463
-
Prion protein biology
-
Prusiner, S.B. et al. (1998) Prion protein biology. Cell 93, 337-348
-
(1998)
Cell
, vol.93
, pp. 337-348
-
-
Prusiner, S.B.1
-
4
-
-
0031711595
-
Pathologic conformations of prion proteins
-
Cohen, F.E. and Prusiner, S.B. (1998) Pathologic conformations of prion proteins. Annu. Rev. Biochem. 67, 793-819
-
(1998)
Annu. Rev. Biochem.
, vol.67
, pp. 793-819
-
-
Cohen, F.E.1
Prusiner, S.B.2
-
5
-
-
0028876473
-
Neuropathological diagnostic criteria for Creutzfeldt-Jakob disease (CJD) and other human spongiform encephalopathies (prion diseases)
-
Budka, H. et al. (1995) Neuropathological diagnostic criteria for Creutzfeldt-Jakob disease (CJD) and other human spongiform encephalopathies (prion diseases). Brain Pathol. 5, 459-466
-
(1995)
Brain Pathol.
, vol.5
, pp. 459-466
-
-
Budka, H.1
-
6
-
-
0029657958
-
Human prion diseases
-
Ironside, J.W. et al. (1996) Human prion diseases. J. Neural Transm. 47, 231-246
-
(1996)
J. Neural Transm.
, vol.47
, pp. 231-246
-
-
Ironside, J.W.1
-
7
-
-
0027757723
-
Pathology of nonhuman spongiform encephalopathies: Variations and their implications for pathogenesis
-
Wells, G.A. (1993) Pathology of nonhuman spongiform encephalopathies: variations and their implications for pathogenesis. Dev. Biol. Stand. 80, 61-69
-
(1993)
Dev. Biol. Stand.
, vol.80
, pp. 61-69
-
-
Wells, G.A.1
-
8
-
-
0033598441
-
Vacuolation in murine prion disease: An informative artefact
-
Betmouni, S. et al. (1999) Vacuolation in murine prion disease: an informative artefact. Curr. Biol. 9, R677-R679
-
(1999)
Curr. Biol.
, vol.9
-
-
Betmouni, S.1
-
9
-
-
0345654322
-
Neuronal apoptosis in Creutzfeldt-Jakob disease
-
Gray, F. et al. (1999) Neuronal apoptosis in Creutzfeldt-Jakob disease. J. Neuropathol. Exp. Neurol. 58, 321-328
-
(1999)
J. Neuropathol. Exp. Neurol.
, vol.58
, pp. 321-328
-
-
Gray, F.1
-
10
-
-
0029784248
-
Evidence for an early inflammatory response in the central nervous system of mice with scrapie
-
Betmouni, S. et al. (1996) Evidence for an early inflammatory response in the central nervous system of mice with scrapie. Neuroscience 74, 1-5
-
(1996)
Neuroscience
, vol.74
, pp. 1-5
-
-
Betmouni, S.1
-
11
-
-
15844415943
-
Prion protein amyloidosis
-
Ghetti, B. et al. (1996) Prion protein amyloidosis. Brain Pathol. 6, 127-145
-
(1996)
Brain Pathol.
, vol.6
, pp. 127-145
-
-
Ghetti, B.1
-
12
-
-
0029169770
-
Pathology of the transmissible spongiform encephalopathies with special emphasis on ultrastructure
-
Jeffrey, M. et al. (1995) Pathology of the transmissible spongiform encephalopathies with special emphasis on ultrastructure. Micron 26, 277-298
-
(1995)
Micron
, vol.26
, pp. 277-298
-
-
Jeffrey, M.1
-
13
-
-
0032802332
-
Cellular biology of prion diseases
-
Harris, D.A. (1999) Cellular biology of prion diseases. Clin. Microbiol. Rev. 12, 429-444
-
(1999)
Clin. Microbiol. Rev.
, vol.12
, pp. 429-444
-
-
Harris, D.A.1
-
14
-
-
0034665847
-
Signal transduction through prion protein
-
Mouillet-Richard, S. et al. (2000) Signal transduction through prion protein. Science 289, 1925-1928
-
(2000)
Science
, vol.289
, pp. 1925-1928
-
-
Mouillet-Richard, S.1
-
15
-
-
0035977053
-
C directly interacts with proteins involved in signaling pathways
-
C directly interacts with proteins involved in signaling pathways. J. Biol. Chem. 276, 44604-44612
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 44604-44612
-
-
Spielhaupter, C.1
Schatzl, H.M.2
-
16
-
-
18444397736
-
Stress-inducible protein 1 is a cell surface ligand for cellular prion that triggers neuroprotection
-
Zanata, S.M. et al. (2002) Stress-inducible protein 1 is a cell surface ligand for cellular prion that triggers neuroprotection. EMBO J. 21, 3307-3316
-
(2002)
EMBO J.
, vol.21
, pp. 3307-3316
-
-
Zanata, S.M.1
-
17
-
-
0027439595
-
Identification of a 60-kilodalton stress-related protein, p60, which interacts with hsp90 and hsp70
-
Smith, D.F. et al. (1993) Identification of a 60-kilodalton stress-related protein, p60, which interacts with hsp90 and hsp70. Mol. Cell. Biol. 13, 869-876
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 869-876
-
-
Smith, D.F.1
-
18
-
-
0031036746
-
Stress-inducible, murine protein mSTI1. Characterization of binding domains for heat shock proteins and in vitro phosphorylation by different kinases
-
Lassle, M. et al. (1997) Stress-inducible, murine protein mSTI1. Characterization of binding domains for heat shock proteins and in vitro phosphorylation by different kinases. J. Biol. Chem. 272, 1876-1884
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 1876-1884
-
-
Lassle, M.1
-
19
-
-
0036645677
-
Cellular prion protein transduces neuroprotective signals
-
Chiarini, L.B. et al. (2002) Cellular prion protein transduces neuroprotective signals. EMBO J. 21, 3317-3326
-
(2002)
EMBO J.
, vol.21
, pp. 3317-3326
-
-
Chiarini, L.B.1
-
20
-
-
0027483615
-
Neurotoxicity of a prion protein fragment
-
Forloni, G. et al. (1993) Neurotoxicity of a prion protein fragment. Nature 362, 543-546
-
(1993)
Nature
, vol.362
, pp. 543-546
-
-
Forloni, G.1
-
21
-
-
0027259274
-
Molecular characteristics of a protease-resistant, amyloidogenic and neurotoxic peptide homologous to residues 106-126 of the prion protein
-
Selvaggini, C. et al. (1993) Molecular characteristics of a protease-resistant, amyloidogenic and neurotoxic peptide homologous to residues 106-126 of the prion protein. Biochem. Biophys. Res. Commun. 194, 1380-1386
-
(1993)
Biochem. Biophys. Res. Commun.
, vol.194
, pp. 1380-1386
-
-
Selvaggini, C.1
-
22
-
-
0028925377
-
Prion protein peptides induce α-helix to β-sheet conformational transitions
-
Nguyen, J. et al. (1995) Prion protein peptides induce α-helix to β-sheet conformational transitions. Biochemistry 34, 4186-4192
-
(1995)
Biochemistry
, vol.34
, pp. 4186-4192
-
-
Nguyen, J.1
-
23
-
-
0028143841
-
Mouse cortical cells lacking cellular PrP survive in culture with a neurotoxic PrP fragment
-
Brown, D.R. et al. (1994) Mouse cortical cells lacking cellular PrP survive in culture with a neurotoxic PrP fragment. Neuroreport 5, 2057-2060
-
(1994)
Neuroreport
, vol.5
, pp. 2057-2060
-
-
Brown, D.R.1
-
24
-
-
0033566067
-
Prions prevent neuronal cell-line death
-
Kuwahara, C. et al. (1999) Prions prevent neuronal cell-line death. Nature 400, 225-226
-
(1999)
Nature
, vol.400
, pp. 225-226
-
-
Kuwahara, C.1
-
25
-
-
0034931131
-
Interaction of prion proteins with cell surface receptors, molecular chaperones, and other molecules
-
Gauczynski, S. et al. (2001) Interaction of prion proteins with cell surface receptors, molecular chaperones, and other molecules. Adv. Protein Chem. 57, 229-272
-
(2001)
Adv. Protein Chem.
, vol.57
, pp. 229-272
-
-
Gauczynski, S.1
-
26
-
-
0029932071
-
Analysis of interaction sites in homo- and heteromeric complexes containing Bcl-2 family members and the cellular prion protein
-
Kurschner, C. and Morgan, J.I. (1996) Analysis of interaction sites in homo- and heteromeric complexes containing Bcl-2 family members and the cellular prion protein. Brain Res. Mol. Brain Res. 37, 249-258
-
(1996)
Brain Res. Mol. Brain Res.
, vol.37
, pp. 249-258
-
-
Kurschner, C.1
Morgan, J.I.2
-
27
-
-
0035914410
-
Prion protein protects human neurons against Bax-mediated apoptosis
-
Bounhar, Y. et al. (2001) Prion protein protects human neurons against Bax-mediated apoptosis. J. Biol. Chem. 276, 39145-39149
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 39145-39149
-
-
Bounhar, Y.1
-
28
-
-
0033695126
-
Prion protein devoid of the octapeptide repeat region restores susceptibility to scrapie in PrP knockout mice
-
Flechsig, E. et al. (2000) Prion protein devoid of the octapeptide repeat region restores susceptibility to scrapie in PrP knockout mice. Neuron 27, 399-408
-
(2000)
Neuron
, vol.27
, pp. 399-408
-
-
Flechsig, E.1
-
29
-
-
0035872476
-
Copper and prion disease
-
Brown, D.R. (2001) Copper and prion disease. Brain Res. Bull. 55, 165-173
-
(2001)
Brain Res. Bull.
, vol.55
, pp. 165-173
-
-
Brown, D.R.1
-
30
-
-
0015589898
-
Clinical and histological recovery from the scrapie-like spongiform encephalopathy produced in mice by feeding them with cuprizone
-
Pattison, I.H. and Jebbett, J.N. (1973) Clinical and histological recovery from the scrapie-like spongiform encephalopathy produced in mice by feeding them with cuprizone. J. Pathol. 109, 245-250
-
(1973)
J. Pathol.
, vol.109
, pp. 245-250
-
-
Pattison, I.H.1
Jebbett, J.N.2
-
31
-
-
0014530743
-
Spongiform encephalopathy induced in rats and guinea pigs by cuprizone
-
Carlton, W.W. (1969) Spongiform encephalopathy induced in rats and guinea pigs by cuprizone. Exp. Mol. Pathol. 10, 274-287
-
(1969)
Exp. Mol. Pathol.
, vol.10
, pp. 274-287
-
-
Carlton, W.W.1
-
32
-
-
0035907363
-
Prion protein binds copper within the physiological concentration range
-
Kramer, M.L. et al. (2001) Prion protein binds copper within the physiological concentration range. J. Biol. Chem. 276, 16711-16719
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 16711-16719
-
-
Kramer, M.L.1
-
33
-
-
0031444294
-
The cellular prion protein binds copper in vivo
-
Brown, D.R. et al. (1997) The cellular prion protein binds copper in vivo. Nature 390, 684-687
-
(1997)
Nature
, vol.390
, pp. 684-687
-
-
Brown, D.R.1
-
34
-
-
0033571055
-
Normal prion protein has an activity like that of superoxide dismutase
-
Brown, D.R. et al. (1999) Normal prion protein has an activity like that of superoxide dismutase. Biochem. J. 344, 1-5
-
(1999)
Biochem. J.
, vol.344
, pp. 1-5
-
-
Brown, D.R.1
-
35
-
-
0034678023
-
Brain copper content and cuproenzyme activity do not vary with prion protein expression level
-
Waggoner, D.J. et al. (2000) Brain copper content and cuproenzyme activity do not vary with prion protein expression level. J. Biol. Chem. 275, 7455-7458
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 7455-7458
-
-
Waggoner, D.J.1
-
36
-
-
0037083888
-
Metal imbalance and compromised antioxidant function are early changes in prion disease
-
Thackray, A.M. et al. (2002) Metal imbalance and compromised antioxidant function are early changes in prion disease. Biochem. J. 362, 253-258
-
(2002)
Biochem. J.
, vol.362
, pp. 253-258
-
-
Thackray, A.M.1
-
37
-
-
0034764599
-
Oxidative impairment in scrapie-infected mice is associated with brain metals perturbations and altered antioxidant activities
-
Wong, B.S. et al. (2001) Oxidative impairment in scrapie-infected mice is associated with brain metals perturbations and altered antioxidant activities. J. Neurochem. 79, 689-698
-
(2001)
J. Neurochem.
, vol.79
, pp. 689-698
-
-
Wong, B.S.1
-
38
-
-
0034810585
-
Aberrant metal binding by prion protein in human prion disease
-
Wong, B.S. et al. (2001) Aberrant metal binding by prion protein in human prion disease. J. Neurochem. 78, 1400-1408
-
(2001)
J. Neurochem.
, vol.78
, pp. 1400-1408
-
-
Wong, B.S.1
-
39
-
-
0027096137
-
Synthesis and trafficking of prion proteins in cultured cells
-
Taraboulos, A. et al. (1992) Synthesis and trafficking of prion proteins in cultured cells. Mol. Biol. Cell 3, 851-863
-
(1992)
Mol. Biol. Cell
, vol.3
, pp. 851-863
-
-
Taraboulos, A.1
-
40
-
-
0032509499
-
Copper stimulates endocytosis of the prion protein
-
Pauly, P.C. and Harris, D.A. (1998) Copper stimulates endocytosis of the prion protein. J. Biol. Chem. 273, 33107-33110
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 33107-33110
-
-
Pauly, P.C.1
Harris, D.A.2
-
41
-
-
0034705438
-
Copper(II)-induced conformational changes and protease resistance in recombinant and cellular PrP. Effect of protein age and deamidation
-
Qin, K. et al. (2000) Copper(II)-induced conformational changes and protease resistance in recombinant and cellular PrP. Effect of protein age and deamidation. J. Biol. Chem. 275, 19121-19131
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 19121-19131
-
-
Qin, K.1
-
42
-
-
0032488777
-
A transmembrane form of the prion protein in neurodegenerative disease
-
Hegde, R.S. et al. (1998) A transmembrane form of the prion protein in neurodegenerative disease. Science 279, 827-834
-
(1998)
Science
, vol.279
, pp. 827-834
-
-
Hegde, R.S.1
-
43
-
-
0033576323
-
Transmissible and genetic prion diseases share a common pathway of neurodegeneration
-
Hegde, R.S. et al. (1999) Transmissible and genetic prion diseases share a common pathway of neurodegeneration. Nature 402, 822-826
-
(1999)
Nature
, vol.402
, pp. 822-826
-
-
Hegde, R.S.1
-
44
-
-
0037195617
-
Sc-like conformation in the cytosol
-
Sc-like conformation in the cytosol. Science 298, 1785-1788
-
(2002)
Science
, vol.298
, pp. 1785-1788
-
-
Ma, J.1
Lindquist, S.2
-
45
-
-
0037195647
-
Neurotoxicity and neurodegeneration when PrP accumulates in the cytosol
-
Ma, J. et al. (2002) Neurotoxicity and neurodegeneration when PrP accumulates in the cytosol. Science 298, 1781-1785
-
(2002)
Science
, vol.298
, pp. 1781-1785
-
-
Ma, J.1
-
46
-
-
0036606540
-
ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats
-
Nishitoh, H. et al. (2002) ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats. Genes Dev. 16, 1345-1355
-
(2002)
Genes Dev.
, vol.16
, pp. 1345-1355
-
-
Nishitoh, H.1
-
47
-
-
0035865398
-
Onset of ataxia and Purkinje cell loss in PrP null mice inversely correlated with Dpl level in brain
-
Rossi, D. et al. (2001) Onset of ataxia and Purkinje cell loss in PrP null mice inversely correlated with Dpl level in brain. EMBO J. 20, 694-702
-
(2001)
EMBO J.
, vol.20
, pp. 694-702
-
-
Rossi, D.1
-
49
-
-
0026600865
-
Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein
-
Bueler, H. et al. (1992) Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein. Nature 356, 577-582
-
(1992)
Nature
, vol.356
, pp. 577-582
-
-
Bueler, H.1
-
50
-
-
0028420937
-
129/Ola mice carrying a null mutation in PrP that abolishes mRNA production are developmentally normal
-
Manson, J.C. et al. (1994) 129/Ola mice carrying a null mutation in PrP that abolishes mRNA production are developmentally normal. Mol. Neurobiol. 8, 121-127
-
(1994)
Mol. Neurobiol.
, vol.8
, pp. 121-127
-
-
Manson, J.C.1
-
51
-
-
13344282734
-
Loss of cerebellar Purkinje cells in aged mice homozygous for a disrupted PrP gene
-
Sakaguchi, S. et al. (1996) Loss of cerebellar Purkinje cells in aged mice homozygous for a disrupted PrP gene. Nature 380, 528-531
-
(1996)
Nature
, vol.380
, pp. 528-531
-
-
Sakaguchi, S.1
-
52
-
-
0033215478
-
Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel
-
Moore, R.C. et al. (1999) Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel. J. Mol. Biol. 292, 797-817
-
(1999)
J. Mol. Biol.
, vol.292
, pp. 797-817
-
-
Moore, R.C.1
-
53
-
-
0036304151
-
Differences between the prion protein and its homolog Doppel: A partially structured state with implications for scrapie formation
-
Nicholson, E.M. et al. (2002) Differences between the prion protein and its homolog Doppel: a partially structured state with implications for scrapie formation. J. Mol. Biol. 316, 807-815
-
(2002)
J. Mol. Biol.
, vol.316
, pp. 807-815
-
-
Nicholson, E.M.1
-
54
-
-
0035021524
-
The PrP-like protein Doppel gene in sheep and cattle: cDNA sequence and expression
-
Tranulis, M.A. et al. (2001) The PrP-like protein Doppel gene in sheep and cattle: cDNA sequence and expression. Mamm. Genome 12, 376-379
-
(2001)
Mamm. Genome
, vol.12
, pp. 376-379
-
-
Tranulis, M.A.1
-
55
-
-
0037099695
-
Absence of the prion protein homologue Doppel causes male sterility
-
Behrens, A. et al. (2002) Absence of the prion protein homologue Doppel causes male sterility. EMBO J. 21, 3652-3658
-
(2002)
EMBO J.
, vol.21
, pp. 3652-3658
-
-
Behrens, A.1
-
56
-
-
0035909931
-
Doppel-induced cerebellar degeneration in transgenic mice
-
Moore, R.C. et al. (2001) Doppel-induced cerebellar degeneration in transgenic mice. Proc. Natl. Acad. Sci. U. S. A. 98, 15288-15293
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 15288-15293
-
-
Moore, R.C.1
-
57
-
-
0035042258
-
Normal neurogenesis and scrapie pathogenesis in neural grafts lacking the prion protein homologue Doppel
-
Behrens, A. et al. (2001) Normal neurogenesis and scrapie pathogenesis in neural grafts lacking the prion protein homologue Doppel. EMBO Rep. 2, 347-352
-
(2001)
EMBO Rep.
, vol.2
, pp. 347-352
-
-
Behrens, A.1
-
58
-
-
0036184716
-
Expression of doppel in the CNS ofmice does not modulate transmissible spongiform encephalopathy disease
-
Tuzi, N.L. et al. (2002) Expression of doppel in the CNS ofmice does not modulate transmissible spongiform encephalopathy disease. J. Gen. Virol. 83, 705-711
-
(2002)
J. Gen. Virol.
, vol.83
, pp. 705-711
-
-
Tuzi, N.L.1
-
59
-
-
0001552281
-
Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions
-
Shmerling, D. et al. (1998) Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions. Cell 93, 203-214
-
(1998)
Cell
, vol.93
, pp. 203-214
-
-
Shmerling, D.1
-
60
-
-
0036470471
-
Post-natal knockout of prion protein alters hippocampal CA1 properties, but does not result in neurodegeneration
-
Mallucci, G.R. et al. (2002) Post-natal knockout of prion protein alters hippocampal CA1 properties, but does not result in neurodegeneration. EMBO J. 21, 202-210
-
(2002)
EMBO J.
, vol.21
, pp. 202-210
-
-
Mallucci, G.R.1
-
61
-
-
0037080043
-
Lack of prion protein expression results in a neuronal phenotype sensitive to stress
-
Brown, D.R. et al. (2002) Lack of prion protein expression results in a neuronal phenotype sensitive to stress. J. Neurosci. Res. 67, 211-224
-
(2002)
J. Neurosci. Res.
, vol.67
, pp. 211-224
-
-
Brown, D.R.1
|