Evidence for an early inflammatory response in the central nervous system of mice with scrapie

Neuroscience

Volumn 74, Issue 1, 1996, Pages 1-5

  Betmouni, S ^c   Perry, V H ^a   Gordon, J L ^b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b Neures Limited   (United Kingdom)

^c NONE

Author keywords

immunocytochemistry; inflammation; microglia; scrapie; T cells

Indexed keywords

CD3 ANTIGEN; GLIAL FIBRILLARY ACIDIC PROTEIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; CENTRAL NERVOUS SYSTEM; DEGENERATIVE DISEASE; IMMUNOCYTOCHEMISTRY; INFLAMMATION; MICROGLIA; MOUSE; NEUROPATHOLOGY; NONHUMAN; PRION; PRION DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RODENT DISEASE; SHEEP DISEASE; T LYMPHOCYTE;

EID: 0029784248     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/0306-4522(96)00212-6     Document Type: Article

References (30)

1. Andersson P.-B., Perry V. H. and Gordon S. (1991) The kinetics and morphological characteristics of the macrophage-microglial response to kainic acid-induced neuronal degeneration. Neuroscience 42, 201-214.
2. Andersson P.-B., Perry V. H. and Gordon S. (1992) The acute inflammatory response to lipopolysaccharide in CNS parenchyma differs from that in other body tissues. Neuroscience 48, 169-186.
3. Braak H. and Braak E. (1991) Neuropathological staging of Alzheimer-related changes. Acta neuropath. 82, 239-259.
4. Breitner J. C. S., Gau B. A., Welsh K. A., Plassman B. L., McDonald W. M., Helms M. J. and Anthony J. C. (1994) Inverse association of anti-inflammatory treatments and Alzheimer's Disease: initial results of a co-twin control study. Neurology 44, 227-232.
5. Brown P. (1990) The phantasmagoric immunology of transmissible spongiform encephalopathy. In Immunologic Mechanisms in Neurologic and Psychiatric Disease (ed. Waksman B. H.), pp. 305-313. Raven, New York.
6. Caughey B. and Raymond G. J. (1991) The Scrapie-associated form of PrP is made from a cell surface precursor that is both protease and phospholipase sensitive. J. biol. Chem. 266, 18,217-18,223.
7. Chandler R. L. (1961) Encephalopathy in mice produced by inoculation with scrapie brain material. Lancet 1, 1378-1379.
8. Cobbold S. P., Jayasuriya A., Nas A., Prospero T. D. and Waldman H. (1984) Therapy with monoclonal antibodies by elimination of T-cell subsets in vivo. Nature 312, 548-551.
9. De Armond S. J. and Prusiner S. B. (1993) The neurochemistry of Prion diseases. J. Neurochem. 1589-1601.
10. DeArmond S. J. (1993) Alzheimer's disease and Creutzfeldt-Jakob disease: overlap of pathogenic mechanisms. Curr. Opin. Neurol. 6, 872-881.
11. Ehresmann D. W. and Hogan R. H. (1986) Acceleration of scrapie disease in mice by an adenovirus. Intervirology 25, 103-110.
12. Eikelenboom P., Scott J. R. McBride P. A., Rozemuller J. M., Bruce M. E. and Fraser H. (1987) No evidence for involvement of plasma proteins or blood-borne cells in amyloid plaque formation in scrapie-affected mice. Virchows Arch. B 53, 251-256.
13. Eikelenboom P., Zhan S.-S., van Gool W. A. and Allsop D. (1994) Inflammatory mechanisms in Alzheimer's Disease. Trends pharmac. Sci. 15, 447-450.
14. Forloni G., Angeretti N., Chiesa R., Monzani E., Salmona M., Buglani O. and Tagliavini F. (1993) Neurotoxicity of a prion protein fragment. Nature 362, 543-546.
15. Lawson L. J., Perry V. H., Dri P. and Gordon S. (1990) Heterogeneity in the distribution and morphology of microglia in normal adult mouse brain. Neuroscience 39, 151-170.
16. Mattson M. P., Cheng B., Davis D., Bryant K., Ivan L. and Rydel R. E. (1992) Beta amyloid peptides destabilise calcium homeostasis and render human cortical neurones vulnerable to excitotoxicity. J. Neurosci. 12, 376-389.
17. McFarlin D. E., Raff M. C., Simpson E. and Nehlsen S. H. (1971) Scrapie in immunologically deficient mice. Nature 233, 336.
18. McGeer P. L., Kawamata T., Walker D. G., Akiyama H., Tooyama I. and McGeer E. G. (1993) Microglia in degenerative neurological disease. Glia 7, 84-92.
19. McGeer P. L. and Rogers J. (1992) Anti-inflammatory agents as a therapeutic approach to Alzheimer's Disease. Neurology 42, 447-449.
20. Outram G. W., Dickinson A. G. and Fraser H. (1974) Reduced susceptibility to scrapie in mice after steroid administration. Nature 249, 855-856.
21. Perry V. H., Andersson P.-B. and Gordon S. (1993) Macrophages and inflammation in the central nervous system. Trends Neurosci. 16, 268-273.
22. Prusiner S. B. (1982) Novel proteinaceous infectious particles cause scrapie. Science 216, 136-144.
23. Prusiner S. B. (1995) The Prion Diseases. Scientific American January 272, 30-37.
24. Rabinowitz S. S. and Gordon S. (1991) Macrosialin, a macrophage restricted membrane sialoprotein differentially glycosylated in response to inflammatory stimuli. J. exp. Med. 174, 827-836.
25. Rogers J., Kirby L. C., Hempleman S. R. Berry D. L., McGeer P. L., Kaszniak A. W., Zaliniski J., Cofield M., Mansukhani L., Wilson P. and Kogan F. (1993) Clinical trial of indomethacin in Alzheimer's Disease. Neurology 43, 1609-1611.
26. Scott J. R., Davies D. and Fraser H. (1992) Scrapie in the central nervous system: neuroanatomical spread of infection and Sine control of pathogenesis. J. Gen. Virol. 73, 1637-1644.
27. Springer T. A. (1980) Cell surface differentiation in the mouse. Characterisation of "Jumping" and "Lineage" antigens using xenogeneic rat monoclonal antibodies. In Monoclonal Antibodies and Hybridomas; a New Dimension in Biological Analysis (eds Kennett R. H., McKearn T. J. and Bechtol K. B.), pp. 185-217. Plenum, New York.
28. Tomonari K. (1988). A rat antibody against a structure functionally related to the mouse T-cell receptor/T3 complex. Immunogenetics 28, 455-458.
29. Williams A. E., Lawson L. J., Perry V. H. and Fraser H. (1994) Characterization of the microglial response in murine scrapie. Neuropath. appl. Neurobiol. 20, 47-55.
30. Younkin S. G. (1991) Processing of the Alzheimer's Disease beta-A4 amyloid protein precursor (APP). Brain Pathol. 1, 253-262.