Prion Protein Binds Copper within the Physiological Concentration Range

Journal of Biological Chemistry

Volumn 276, Issue 20, 2001, Pages 16711-16719

  Kramer, Michael L ^a   Kratzin, Hartmut D ^b   Schmidt, Bernhard ^a   Römer, Alice ^a   Windl, Otto ^a,e   Liemann, Susanne ^c   Hornemann, Simone ^d   Kretzschmar, Hans ^a,e  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b MAX PLANCK INSTITUTE OF EXPERIMENTAL MEDICINE   (Germany)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^e UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD; FLUORESCENCE; MASS SPECTROMETRY; METABOLISM; PHYSIOLOGY; PROTEINS; STOICHIOMETRY;

FLUORESCENCE SPECTROSCOPY;

BIOCHEMISTRY;

COPPER ION; GENOMIC DNA; PRION PROTEIN; SYNTHETIC PEPTIDE; COPPER; PEPTIDE FRAGMENT;

ARTICLE; BINDING AFFINITY; COPPER METABOLISM; DEGENERATIVE DISEASE; FLUORESCENCE SPECTROSCOPY; GENE EXPRESSION; MASS SPECTROMETRY; METAL BINDING; NEUROLOGIC DISEASE; NONHUMAN; NUCLEOTIDE SEQUENCE; PEPTIDE ANALYSIS; PLASMID; POLYMERASE CHAIN REACTION; PRION DISEASE; PRIORITY JOURNAL; PROTEIN ANALYSIS; STOICHIOMETRY; ANIMAL; BINDING SITE; CHEMISTRY; ELECTROSPRAY MASS SPECTROMETRY; HUMAN; KINETICS; METABOLISM; MOUSE; PH; PRION; PROTEIN CONFORMATION; SPECTROFLUOROMETRY; SYNTHESIS;

ANIMALS; BINDING SITES; COPPER; HUMANS; HYDROGEN-ION CONCENTRATION; KINETICS; MICE; PEPTIDE FRAGMENTS; PRIONS; PROTEIN CONFORMATION; SPECTROMETRY, FLUORESCENCE; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 0035907363     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M006554200     Document Type: Article

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