-
1
-
-
0032969681
-
Caspases and apoptosis
-
Vaux DL. Caspases and apoptosis. Cell Death Differ 1999;6:493-4.
-
(1999)
Cell Death Differ
, vol.6
, pp. 493-494
-
-
Vaux, D.L.1
-
2
-
-
0028943734
-
Apoptosis in the pathogenesis and treatment of disease
-
Thompson CB. Apoptosis in the pathogenesis and treatment of disease. Science 1995;267:1456-62.
-
(1995)
Science
, vol.267
, pp. 1456-1462
-
-
Thompson, C.B.1
-
3
-
-
0028972616
-
Regulation of apoptosis by bcl-2 family proteins and its role in cancer and chemoresistance
-
Reed JC. Regulation of apoptosis by bcl-2 family proteins and its role in cancer and chemoresistance. Curr Opin Oncol 1995;7: 541-6.
-
(1995)
Curr Opin Oncol
, vol.7
, pp. 541-546
-
-
Reed, J.C.1
-
4
-
-
0028941441
-
Inhibition of apoptosis during development of colorectal cancer
-
Bedi A, Pasricha PJ, Akhtar AJ, et al. Inhibition of apoptosis during development of colorectal cancer. Cancer Res 1995;55: 1811-6.
-
(1995)
Cancer Res
, vol.55
, pp. 1811-1816
-
-
Bedi, A.1
Pasricha, P.J.2
Akhtar, A.J.3
-
5
-
-
0029665123
-
Apoptosis and metastasis: A superior resistance of metastatic cancer cells to programmed cell death
-
Glinsky GV, Glinsky VV. Apoptosis and metastasis: a superior resistance of metastatic cancer cells to programmed cell death. Cancer Lett 1996;101:43-51.
-
(1996)
Cancer Lett
, vol.101
, pp. 43-51
-
-
Glinsky, G.V.1
Glinsky, V.V.2
-
6
-
-
0023748414
-
Genetic alterations during colorectal-tumor development
-
Vogelstein B, Fearon ER, Hamilton SR, et al. Genetic alterations during colorectal-tumor development. N Engl J Med 1988;319: 525-32.
-
(1988)
N Engl J Med
, vol.319
, pp. 525-532
-
-
Vogelstein, B.1
Fearon, E.R.2
Hamilton, S.R.3
-
7
-
-
0025663572
-
Origins of human cancer revisited
-
Stanbridge EJ, Nowell PC. Origins of human cancer revisited. Cell 1990;63:867-74.
-
(1990)
Cell
, vol.63
, pp. 867-874
-
-
Stanbridge, E.J.1
Nowell, P.C.2
-
8
-
-
0035252592
-
E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis
-
Muller H, Bracken AP, Vernell R, et al. E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis. Genes Dev 2001;15:267-85.
-
(2001)
Genes Dev
, vol.15
, pp. 267-285
-
-
Muller, H.1
Bracken, A.P.2
Vernell, R.3
-
9
-
-
0029805888
-
The molecular basis of E2F-1/DP-1-induced S-phase entry and apoptosis
-
Shan B, Farmer AA, Lee WH. The molecular basis of E2F-1/DP-1-induced S-phase entry and apoptosis. Cell Growth Differ 1996; 7:689-97.
-
(1996)
Cell Growth Differ
, vol.7
, pp. 689-697
-
-
Shan, B.1
Farmer, A.A.2
Lee, W.H.3
-
11
-
-
0030850752
-
E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction
-
Hsieh JK, Fredersdorf S, Kouzarides T, Martin K, Lu X. E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction. Genes Dev 1997;11:1840-52.
-
(1997)
Genes Dev
, vol.11
, pp. 1840-1852
-
-
Hsieh, J.K.1
Fredersdorf, S.2
Kouzarides, T.3
Martin, K.4
Lu, X.5
-
12
-
-
0030739355
-
Induction of DNA synthesis and apoptosis are separable functions of E2F-1
-
Phillips AC, Bates S, Ryan KM, Helin K, Vousden KH. Induction of DNA synthesis and apoptosis are separable functions of E2F-1. Genes Dev 1997;11:1853-63.
-
(1997)
Genes Dev
, vol.11
, pp. 1853-1863
-
-
Phillips, A.C.1
Bates, S.2
Ryan, K.M.3
Helin, K.4
Vousden, K.H.5
-
13
-
-
0030813584
-
Adenovirus-mediated overexpression of the transcription factor E2F-1 induces apoptosis in human breast and ovarian carcinoma cell lines and does not require p53
-
Hunt KK, Deng J, Liu TJ, et al. Adenovirus-mediated overexpression of the transcription factor E2F-1 induces apoptosis in human breast and ovarian carcinoma cell lines and does not require p53. Cancer Res 1997;57:4722-6.
-
(1997)
Cancer Res
, vol.57
, pp. 4722-4726
-
-
Hunt, K.K.1
Deng, J.2
Liu, T.J.3
-
14
-
-
0031992159
-
E2F1-specific induction of apoptosis and p53 accumulation, which is blocked by Mdm2
-
Kowalik TF, DeGregori J, Leone G, Jakoi L, Nevins JR. E2F1-specific induction of apoptosis and p53 accumulation, which is blocked by Mdm2. Cell Growth Differ 1998;9:113-8.
-
(1998)
Cell Growth Differ
, vol.9
, pp. 113-118
-
-
Kowalik, T.F.1
DeGregori, J.2
Leone, G.3
Jakoi, L.4
Nevins, J.R.5
-
15
-
-
0029949784
-
E2F-1 functions in mice to promote apoptosis and suppress proliferation
-
Field SJ, Tsai FY, Kuo F, et al. E2F-1 functions in mice to promote apoptosis and suppress proliferation. Cell 1996;85:549-61.
-
(1996)
Cell
, vol.85
, pp. 549-561
-
-
Field, S.J.1
Tsai, F.Y.2
Kuo, F.3
-
16
-
-
0030738479
-
Distinct roles for E2F proteins in cell growth control and apoptosis
-
DeGregori J, Leone G, Miron A, Jakoi L, Nevins JR. Distinct roles for E2F proteins in cell growth control and apoptosis. Proc Natl Acad Sci U S A 1997;94:7245-50.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 7245-7250
-
-
DeGregori, J.1
Leone, G.2
Miron, A.3
Jakoi, L.4
Nevins, J.R.5
-
17
-
-
0034012005
-
E2F4 and E2F1 have similar proliferative properties but different apoptotic and oncogenic properties in vivo
-
Wang D, Russell JL, Johnson DG. E2F4 and E2F1 have similar proliferative properties but different apoptotic and oncogenic properties in vivo. Mol Cell Biol 2000;20:3417-24.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 3417-3424
-
-
Wang, D.1
Russell, J.L.2
Johnson, D.G.3
-
18
-
-
0032504783
-
p14ARF links the tumour suppressors RB and p53
-
Bates S, Phillips AC, Clark PA, et al. p14ARF links the tumour suppressors RB and p53. Nature 1998;395:124-5.
-
(1998)
Nature
, vol.395
, pp. 124-125
-
-
Bates, S.1
Phillips, A.C.2
Clark, P.A.3
-
19
-
-
0034609798
-
Role for the p53 homologue p73 in E2F-1-induced apoptosis
-
Irwin M, Marin MC, Phillips AC, et al. Role for the p53 homologue p73 in E2F-1-induced apoptosis. Nature 2000;407:645-8.
-
(2000)
Nature
, vol.407
, pp. 645-648
-
-
Irwin, M.1
Marin, M.C.2
Phillips, A.C.3
-
20
-
-
0032575750
-
Caspases: Enemies within
-
Thornberry NA, Lazebnik Y. Caspases: enemies within. Science 1998;281:1312-6.
-
(1998)
Science
, vol.281
, pp. 1312-1316
-
-
Thornberry, N.A.1
Lazebnik, Y.2
-
21
-
-
0033709907
-
Deficiency in caspase-9 or caspase-3 induces compensatory caspase activation
-
Zheng TS, Hunot S, Kuida K, et al. Deficiency in caspase-9 or caspase-3 induces compensatory caspase activation. Nat Med 2000;6:1241-7.
-
(2000)
Nat Med
, vol.6
, pp. 1241-1247
-
-
Zheng, T.S.1
Hunot, S.2
Kuida, K.3
-
22
-
-
0033521741
-
Molecular characterization of mitochondrial apoptosis-inducing factor
-
Susin SA, Lorenzo HK, Zamzami N, et al. Molecular characterization of mitochondrial apoptosis-inducing factor. Nature 1999; 397:441-6.
-
(1999)
Nature
, vol.397
, pp. 441-446
-
-
Susin, S.A.1
Lorenzo, H.K.2
Zamzami, N.3
-
23
-
-
0035967169
-
Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death
-
Joza N, Susin SA, Daugas E, et al. Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death. Nature 2001;410:549-54.
-
(2001)
Nature
, vol.410
, pp. 549-554
-
-
Joza, N.1
Susin, S.A.2
Daugas, E.3
-
24
-
-
0035078404
-
Dominant cell death induction by extramitochondrially targeted apoptosis-inducing factor
-
Loeffler M, Daugas E, Susin SA, et al. Dominant cell death induction by extramitochondrially targeted apoptosis-inducing factor. FASEB J 2001;15:758-67.
-
(2001)
FASEB J
, vol.15
, pp. 758-767
-
-
Loeffler, M.1
Daugas, E.2
Susin, S.A.3
-
25
-
-
0029862706
-
Mitochondrial control of nuclear apoptosis
-
Zamzami N. Susin SA, Marchetti P, et al. Mitochondrial control of nuclear apoptosis. J Exp Med 1996;183:1533-44.
-
(1996)
J Exp Med
, vol.183
, pp. 1533-1544
-
-
Zamzami, N.1
Susin, S.A.2
Marchetti, P.3
-
26
-
-
0034602188
-
Role of BAX in the apoptotic response to anticancer agents
-
Zhang L, Yu J, Park BH, Kinzler KW, Vogelstein B. Role of BAX in the apoptotic response to anticancer agents. Science 2000;290: 989-92.
-
(2000)
Science
, vol.290
, pp. 989-992
-
-
Zhang, L.1
Yu, J.2
Park, B.H.3
Kinzler, K.W.4
Vogelstein, B.5
-
27
-
-
0034630167
-
Induction of apoptosis by cancer chemotherapy
-
Kaufmann SH, Earnshaw WC. Induction of apoptosis by cancer chemotherapy. Exp Cell Res 2000;256:42-9.
-
(2000)
Exp Cell Res
, vol.256
, pp. 42-49
-
-
Kaufmann, S.H.1
Earnshaw, W.C.2
-
28
-
-
0029861452
-
Recombinant adenoviruses with large deletions generated by Cre-mediated excision exhibit different biological properties compared with first-generation vectors in vitro and in vivo
-
Lieber A, He CY, Kirillova I, Kay MA. Recombinant adenoviruses with large deletions generated by Cre-mediated excision exhibit different biological properties compared with first-generation vectors in vitro and in vivo. J Virol 1996;70:8944-60.
-
(1996)
J Virol
, vol.70
, pp. 8944-8960
-
-
Lieber, A.1
He, C.Y.2
Kirillova, I.3
Kay, M.A.4
-
29
-
-
0031749470
-
Overexpression of E2F-1 in glioma triggers apoptosis and suppresses tumor growth in vitro and in vivo
-
Fueyo J, Gomez-Manzano C, Yung WK, et al. Overexpression of E2F-1 in glioma triggers apoptosis and suppresses tumor growth in vitro and in vivo. Nat Med 1998;4:685-90.
-
(1998)
Nat Med
, vol.4
, pp. 685-690
-
-
Fueyo, J.1
Gomez-Manzano, C.2
Yung, W.K.3
-
30
-
-
0027947383
-
Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis
-
Qin XQ, Livingston DM, Kaelin WG Jr, Adams PD. Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis. Proc Natl Acad Sci U S A 1994;91: 10918-22.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 10918-10922
-
-
Qin, X.Q.1
Livingston, D.M.2
Kaelin Jr., W.G.3
Adams, P.D.4
-
31
-
-
0034619773
-
E2F1 mediates ectopic proliferation and stage-specific p53-dependent apoptosis but not aberrant differentiation in the ocular lens of Rb deficient fetuses
-
Liu Y, Zacksenhaus E. E2F1 mediates ectopic proliferation and stage-specific p53-dependent apoptosis but not aberrant differentiation in the ocular lens of Rb deficient fetuses. Oncogene 2000; 19:6065-73.
-
(2000)
Oncogene
, vol.19
, pp. 6065-6073
-
-
Liu, Y.1
Zacksenhaus, E.2
-
32
-
-
0034609864
-
A common E2F-1 and p73 pathway mediates cell death induced by TCR activation
-
Lissy NA, Davis PK, Irwin M, Kaelin WG, Dowdy SF. A common E2F-1 and p73 pathway mediates cell death induced by TCR activation. Nature 2000;407:642-5.
-
(2000)
Nature
, vol.407
, pp. 642-645
-
-
Lissy, N.A.1
Davis, P.K.2
Irwin, M.3
Kaelin, W.G.4
Dowdy, S.F.5
-
33
-
-
0035175931
-
E2F-1 up-regulates c-Myc and p14(ARF) and induces apoptosis in colon cancer cells
-
Elliott MJ, Dong YB, Yang H, McMasters KM. E2F-1 up-regulates c-Myc and p14(ARF) and induces apoptosis in colon cancer cells. Clin Cancer Res 2001;7:3590-7.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 3590-3597
-
-
Elliott, M.J.1
Dong, Y.B.2
Yang, H.3
McMasters, K.M.4
-
34
-
-
0033230581
-
The cellular response to p53: The decision between life and death
-
Sionov RV, Haupt Y. The cellular response to p53: the decision between life and death. Oncogene 1999;18:6145-57.
-
(1999)
Oncogene
, vol.18
, pp. 6145-6157
-
-
Sionov, R.V.1
Haupt, Y.2
-
35
-
-
0028102354
-
Alteration of p53 conformation and induction of apoptosis in a murine erythroleukemia cell line by dimethylsulfoxide
-
Ryan JJ, Clarke MF. Alteration of p53 conformation and induction of apoptosis in a murine erythroleukemia cell line by dimethylsulfoxide. Leuk Res 1994;18:617-21.
-
(1994)
Leuk Res
, vol.18
, pp. 617-621
-
-
Ryan, J.J.1
Clarke, M.F.2
-
36
-
-
0032191393
-
Tumor surveillance via the ARF-p53 pathway
-
Sherr CJ. Tumor surveillance via the ARF-p53 pathway. Genes Dev 1998;12:2984-91.
-
(1998)
Genes Dev
, vol.12
, pp. 2984-2991
-
-
Sherr, C.J.1
-
37
-
-
0028860556
-
E2F-1:DP-1 induces p53 and overrides survival factors to trigger apoptosis
-
Hiebert SW, Packham G, Strom DK, et al. E2F-1:DP-1 induces p53 and overrides survival factors to trigger apoptosis. Mol Cell Biol 1995;15:6864-74.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 6864-6874
-
-
Hiebert, S.W.1
Packham, G.2
Strom, D.K.3
-
38
-
-
0027258466
-
Thymocyte apoptosis induced by p53-dependent and independent pathways
-
Clarke AR, Purdie CA, Harrison DJ, et al. Thymocyte apoptosis induced by p53-dependent and independent pathways. Nature 1993;362:849-52.
-
(1993)
Nature
, vol.362
, pp. 849-852
-
-
Clarke, A.R.1
Purdie, C.A.2
Harrison, D.J.3
-
39
-
-
0344287260
-
Adenovirus-mediated E2F-1 gene transfer efficiently induces apoptosis in melanoma cells
-
Dong YB, Yang HL, Elliott MJ, et al. Adenovirus-mediated E2F-1 gene transfer efficiently induces apoptosis in melanoma cells. Cancer 1999;86:2021-33.
-
(1999)
Cancer
, vol.86
, pp. 2021-2033
-
-
Dong, Y.B.1
Yang, H.L.2
Elliott, M.J.3
-
41
-
-
0031036872
-
Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked
-
Yang J, Liu X, Bhalla K, et al. Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. Science 1997; 275:1129-32.
-
(1997)
Science
, vol.275
, pp. 1129-1132
-
-
Yang, J.1
Liu, X.2
Bhalla, K.3
-
42
-
-
0034805181
-
Overexpression of BCL2 blocks TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in human lung cancer cells
-
Sun SY, Yue P, Zhou JY, et al. Overexpression of BCL2 blocks TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in human lung cancer cells. Biochem Biophys Res Commun 2001;280:788-97.
-
(2001)
Biochem Biophys Res Commun
, vol.280
, pp. 788-797
-
-
Sun, S.Y.1
Yue, P.2
Zhou, J.Y.3
-
43
-
-
0028222955
-
Bcl-2 blocks p53-dependent apoptosis
-
Chiou SK, Rao L, White E. Bcl-2 blocks p53-dependent apoptosis. Mol Cell Biol 1994;14:2556-63.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 2556-2563
-
-
Chiou, S.K.1
Rao, L.2
White, E.3
-
44
-
-
0035884509
-
Transfer of E2F-1 to human glioma cells results in transcriptional up-regulation of Bcl-2
-
Gomez-Manzano C, Mitlianga P, Fueyo J, et al. Transfer of E2F-1 to human glioma cells results in transcriptional up-regulation of Bcl-2. Cancer Res 2001;61:6693-7.
-
(2001)
Cancer Res
, vol.61
, pp. 6693-6697
-
-
Gomez-Manzano, C.1
Mitlianga, P.2
Fueyo, J.3
-
45
-
-
0035950521
-
Bcl-2 is an apoptotic target suppressed by both c-Myc and E2F-1
-
Eischen CM, Packham G, Nip J, et al. Bcl-2 is an apoptotic target suppressed by both c-Myc and E2F-1. Oncogene 2001;20:6983-93.
-
(2001)
Oncogene
, vol.20
, pp. 6983-6993
-
-
Eischen, C.M.1
Packham, G.2
Nip, J.3
-
46
-
-
0000303284
-
Caspase activation and changes in Bcl-2 family member protein expression associated with E2F-1-mediated apoptosis in human esophageal cancer cells
-
Yang HL, Dong YB, Elliott MJ, Liu TJ, McMasters KM. Caspase activation and changes in Bcl-2 family member protein expression associated with E2F-1-mediated apoptosis in human esophageal cancer cells. Clin Cancer Res 2000;6:1579-89.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 1579-1589
-
-
Yang, H.L.1
Dong, Y.B.2
Elliott, M.J.3
Liu, T.J.4
McMasters, K.M.5
-
47
-
-
0031037897
-
The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis
-
Kluck RM, Bossy-Wetzel E, Green DR, Newmeyer DD. The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science 1997;275:1132-6.
-
(1997)
Science
, vol.275
, pp. 1132-1136
-
-
Kluck, R.M.1
Bossy-Wetzel, E.2
Green, D.R.3
Newmeyer, D.D.4
-
48
-
-
0032743892
-
Chemosensitivity of human hepatocellular carcinoma cell line QGY-7703 is related to bcl-2 protein levels
-
Luo D, Cheng SC, Xie H, Xie Y. Chemosensitivity of human hepatocellular carcinoma cell line QGY-7703 is related to bcl-2 protein levels. Tumour Biol 1999;20:331-40.
-
(1999)
Tumour Biol
, vol.20
, pp. 331-340
-
-
Luo, D.1
Cheng, S.C.2
Xie, H.3
Xie, Y.4
-
49
-
-
0032145569
-
Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization
-
Zindy F, Eischen CM, Randle DH, et al. Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization. Genes Dev 1998;12:2424-33.
-
(1998)
Genes Dev
, vol.12
, pp. 2424-2433
-
-
Zindy, F.1
Eischen, C.M.2
Randle, D.H.3
-
50
-
-
0032622050
-
p53-independent increase in E2F-1 expression enhances the cytotoxic effects of etoposide and of adriamycin
-
Meng RD, Phillips P, El-Deiry WS. p53-independent increase in E2F-1 expression enhances the cytotoxic effects of etoposide and of adriamycin. Int J Oncol 1999;14:5-14.
-
(1999)
Int J Oncol
, vol.14
, pp. 5-14
-
-
Meng, R.D.1
Phillips, P.2
El-Deiry, W.S.3
-
51
-
-
0037012034
-
Caspase 9 is required for p53-dependent apoptosis and chemosensitivity in a human ovarian cancer cell line
-
Wu GS, Ding Z. Caspase 9 is required for p53-dependent apoptosis and chemosensitivity in a human ovarian cancer cell line. Oncogene 2002;21:1-8.
-
(2002)
Oncogene
, vol.21
, pp. 1-8
-
-
Wu, G.S.1
Ding, Z.2
-
52
-
-
0035843169
-
Inactivation of the apoptosis effector Apaf-1 in malignant melanoma
-
Soengas MS, Capodieci P, Polsky D, et al. Inactivation of the apoptosis effector Apaf-1 in malignant melanoma. Nature 2001; 409:207-11.
-
(2001)
Nature
, vol.409
, pp. 207-211
-
-
Soengas, M.S.1
Capodieci, P.2
Polsky, D.3
-
53
-
-
0034117177
-
Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis
-
Daugas E, Susin SA, Zamzami N, et al. Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis. FASEB J 2000;14: 729-39.
-
(2000)
FASEB J
, vol.14
, pp. 729-739
-
-
Daugas, E.1
Susin, S.A.2
Zamzami, N.3
|