Promoter structure and cell cycle dependent expression of the human methylpurine-DNA glycosylase gene

Mutation Research - DNA Repair

Volumn 461, Issue 1, 2000, Pages 15-29

  Bouziane, Mohammed ^a,b   Miao, Feng ^a   Bates, Steven E ^a   Somsouk, Lina ^a   Sang, Bi Ching ^b   Denissenko, Mikhail ^b   O'Connor, Timothy R ^a  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^b BD Technologies   (United States)

Author keywords

Cell cycle dependent expression; Human methylpurine DNA glycosylase (MPG) gene; Promoter structure

Indexed keywords

DNA GLYCOSYLTRANSFERASE; PURINE DERIVATIVE;

ARTICLE; CELL CYCLE; DNA DAMAGE; EXCISION REPAIR; GENE MUTATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION;

BASE SEQUENCE; CELL CYCLE; DNA GLYCOSYLASES; DNA REPAIR; FIBROBLASTS; GENE EXPRESSION; HUMANS; MOLECULAR SEQUENCE DATA; N-GLYCOSYL HYDROLASES; PROMOTER REGIONS (GENETICS); TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

ALOCASIA MACRORRHIZOS; ZIZIPHUS MAURITIANA;

EID: 0034665972     PISSN: 09218777     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0921-8777(00)00036-7     Document Type: Article

References (62)

1. Akiyama K., Seki S., Oshida T., Yoshida M.C. Structure, promoter analysis, and chromosomal assignment of the human APEX gene. Biochim. Biophys. Acta. 1219:1994;15-25.
2. Aspinwall R., Rothwell D.G., Roldan-Arjona T., Anselmino C., Ward C.J., Cheadle J.P., Sampson J., Lindahl R.T., Harris P.C., Hickson I.D. Cloning and characterization of a functional human homolog of Escherichia coli endonuclease III. Proc. Natl. Acad. Sci. U. S. A. 94:1997;109-114.
3. Ausubel F.M., Brent R., Kingston R.E., Moore D.D., Seidman J.G., Smith J.A., Struhl K. Short Protocols in Molecular Biology. 2nd edn. 1992;Wiley, New York.
4. Bailly V., Verly W.G. Escherichia coli endonuclease III is not an endonuclease but a b-elimination catalyst. Biochem. J. 242:1987;565-572.
5. Bartek J., Bartkova J., Lukas J. The retinoblastoma protein pathway and the restriction point. Curr. Opin. Cell Biol. 8:1996;805-814.
6. Beard S.E., Capaldi S.R., Gee P. Stress responses to DNA damaging agents in the human colon carcinoma cell line, RKO. Mutat. Res. 371:1996;1-13.
7. Berdal K.G., Johansen R.F., Seeberg E. Release of normal bases from intact DNA by a native DNA repair enzyme. EMBO J. 17:1998;363-367.
8. Bouziane M., Miao F., Ye N., Holmquist G.P., Chyzak G., O'Connor T.R. Repair of DNA alkylation damage. Acta Biochim. Pol. 45:1998;191-202.
9. Bradford M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:1976;248-254.
10. Brent T.P. Suppression of cross-link fromation in chloroethylnitrosourea-treated DNA by an activity in extracts of human leukemic lymphoblasts. Cancer Res. 44:1984;1887-1892.
11. Cerda S.R., Chu S.S., Garcia P., Chung J., Grumet J.D., Thimmapaya B., Weitzman S.A. Regulation of expression of N-methylpurine DNA glycosylase in human mammary epithelial cells: role of transcription factor AP-2. Chem. Res. Toxicol. 12:1999;1098-1109.
12. Cerda S.R., Turk P.W., Thor A.D., Weitzman S.A. Altered expression of the DNA repair protein, N-methylpurine-DNA glycosylase (MPG) in breast cancer. FEBS Lett. 431:1998;12-18.
13. Chakravarti D., Ibeanu G.C., Tano K., Mitra S. Cloning and expression in Escherichia coli of a human cDNA encoding the DNA repair protein N-methylpurine-DNA glycosylase. J. Biol. Chem. 266:1991;15710-15715.
14. Dehazya P., Sirover M.A. Regulation of hypoxanthine DNA glycosylase in normal human and Bloom's syndrome fibroblasts. Cancer Res. 46:1986;3756-3761.
15. Dignam J.D., Lebovitz R.M., Roeder R.G. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11:1983;1475-1489.
16. Engelward B.P., Boosalis M.S., Chen B.J., Deng Z., Siciliano M.J., Samson L. Cloning and characterisation of a mouse 3-methyladenine/7-methylguanine/3-methylguanine-DNA glycosylase cDNA whose gene maps to chromosome 11. Carcinogenesis. 14:1993;175-181.
17. Flint J., Thomas K., Micklem G., Raynham H., Clark K., Doggett N.A., King A., Higgs D.R. The relationship between chromosome structure and function at a human telomeric region. Nat. Genet. 15:1997;252-257.
18. Fortini P., Pascucci B., Parlanti E., Sobol R.W., Wilson S.H., Dogliotti E. Different DNA polymerases are involved in the short- and long-patch base excision repair in mammalian cells. Biochemistry. 37:1998;3575-3580.
19. Frosina G., Fortini P., Rossi O., Carrozzino F., Raspaglio G., Cox I.S., Lane D.P., Abbondandolo A., Dogliotti E. Two pathways for base excision repair in mammalian cells. J. Biol. Chem. 271:1996;9573-9578.
20. Gallagher P.E., Brent T.P. Further purification and characterization of human 3-methyladenine-DNA glycosylase. Biochim. Biophys. Acta. 782:1984;494-501.
21. Gallagher P.E., Brent T.P. Partial purification and characterization of 3-methyladenine-DNA glycosylase from human placenta. Biochemistry. 21:1982;6404-6409.
22. Glassner B.J., Posnick L.M., Samson L.D. The influence of DNA glycosylases on spontaneous mutation. Mutat. Res. 400:1998;33-44.
23. Glassner B.J., Rasmussen L.J., Najarian M.T., Posnick L.M., Samson L.D. Generation of a strong mutator phenotype in yeast by imbalanced base excision repair. Proc. Natl. Acad. Sci. U. S. A. 95:1998;9997-10002.
24. Grombacher T., Kaina B. Isolation and analysis of inducibility of the rat N-methylpurine-DNA glycosylase promoter. DNA Cell Biol. 15:1996;581-588.
25. Gunther M., Frebourg T., Laithier M., Fossar N., Bouziane-Ouartini M., Lavialle C., Brison O. An Sp1 binding site and the minimal promoter contribute to overexpression of the cytokeratin 18 gene in tumorigenic clones relative to that in nontumorigenic clones of a human carcinoma cell line. Mol. Cell Biol. 15:1995;2490-2499.
26. Gupta P.K., Sirover M.A. Sequential stimulation of DNA repair and DNA replication in normal human cells. Mutat. Res. 72:1980;273-284.
27. Hang B., Singer B., Margison G.P., Elder R.H. Targeted deletion of alkylpurine-DNA-N-glycosylase in mice eliminates repair of 1,N6-ethenoadenine and hypoxanthine but not of 3,N4-ethenocytosine or 8-oxoguanine. Proc. Natl. Acad. Sci. U. S. A. 94:1997;12869-12874.
28. Harrison L., Ascione A.G., Wilson D.M., Demple B. Characterization of the promoter of the human apurinic endonuclease gene (APE). J. Biol. Chem. 270:1995;5556-5564.
29. Helin K. Regulation of cell proliferation by the E2F transcription factors. Curr. Opin. Genet. Dev. 8:1998;28-35.
30. Hilbert T.P., Chaung W., Boorstein R.J., Cunningham R.P., Teebor G.W. Cloning and expression of the cDNA encoding the human homologue of the DNA repair enzyme, Escherichia coli endonuclease III. J. Biol. Chem. 272:1997;6733-6740.
31. Holmquist G.P. Endogenous lesions, S-phase-independent spontaneous mutations, and evolutionary strategies for base excision repair. Mutat. Res. 400:1998;59-68.
32. Iyer V.R., Eisen M.B., Ross D.T., Schuler G., Moore T., Lee J.C.F., Trent J.M., Staudt L.M., Hudson J. Jr., Boguski M.S., Lashkari D., Shalon D., Botstein D., Brown P.O. The transcriptional program in the response of human fibroblasts to serum. Science. 283:1999;83-87.
33. Izumi T., Tatsuka M., Tano K., Asano M., Mitra S. Molecular cloning and characterization of the promoter of the human N-methylpurine-DNA glycosylase (MPG) gene. Carcinogenesis. 18:1997;1837-1839.
34. Klungland A., Lindahl T. Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1). EMBO J. 16:1997;3341-3348.
35. Lania L., Majello B., Napolitano G. Transcriptional control by cell-cycle regulators: a review. J. Cell. Physiol. 179:1999;134-141.
36. Lindahl T. Instability and decay of the primary structure of DNA. Nature. 362:1993;709-715.
37. Lindahl T. An N-glycosidase from Escherichia coli that releases free uracil from DNA containing deaminated cytosine residues. Proc. Natl. Acad. Sci. U. S. A. 71:1974;3649-3653.
38. Lindahl T. New class of enzymes acting on damaged DNA. Nature. 259:1976;64-66.
39. Male R., Haukanes B.I., Helland D.E., Kleppe K. Substrate specificity of 3-methyladenine-DNA glycosylase from calf thymus. Eur. J. Biochem. 165:1987;13-19.
40. Margison G.P., Pegg A.E. Enzymatic release of 7-methylguanine from methylated DNA by rodent liver extracts. Proc. Natl. Acad. Sci. U. S. A. 78:1981;861-865.
41. Marnett L.J., Burcham P.C. Endogenous DNA adducts: potential and paradox. Chem. Res. Toxicol. 6:1993;771-785.
42. Miao F., Bouziane M., O'Connor T.R. Interaction of the recombinant human methylpurine-DNA glycosylase (MPG protein) with oligodeoxyribonucleotides containing either hypoxanthine or abasic sites. Nucleic Acids Res. 26:1998;4034-4041.
43. Narayan S., He F., Wilson S.H. Activation of the human DNA polymerase beta promoter by a DNA-alkylating agent through induced phosphorylation of cAMP response element-binding protein-1. J. Biol. Chem. 271:1996;18508-18513.
44. Novina C.D., Roy A.L. Core promoters and transcriptional control. Trends Genet. 12:1996;351-355.
45. O'Connor T.R. Purification and characterisation of human 3-methyladenine-DNA glycosylase. Nucleic Acids Res. 21:1993;5561-5569.
46. Pendlebury A., Frayling I.M., Santibanez Koref M.F., Margison G.P., Rafferty J.A. Evidence for the simultaneous expression of alternatively spliced alkylpurine N-glycosylase transcripts in human tissues and cells. Carcinogenesis. 15:1994;2957-2960.
47. Ramana C.V., Boldogh I., Izumi T., Mitra S. Activation of apurinic/apyrimidinic endonuclease in human cells by reactive oxygen species and its correlation with their adaptive response to genotoxicity of free radicals. Proc. Natl. Acad. Sci. U. S. A. 95:1998;5061-5066.
48. Samson L., Derfler B., Boosalis M., Call K. Cloning and characterization of a 3-methyladenine DNA glycosylase cDNA from human cells whose gene maps to chromosome 16. Proc. Natl. Acad. Sci. U. S. A. 88:1991;9127-9131.
49. Saparbaev M., Kleibl K., Laval J. Escherichia coli, Saccharomyces cerevisiae, rat and human 3-methyladenine DNA glycosylases repair 1,N6-ethenoadenine when present in DNA. Nucleic Acids Res. 23:1995;3750-3755.
50. Saparbaev M., Laval J. Excision of hypoxanthine from DNA containing dIMP residues by the Escherichia coli, yeast, rat, and human alkylpurine DNA glycosylases. Proc. Natl. Acad. Sci. U. S. A. 91:1994;5873-5877.
51. Seeberg E., Eide L., Bjoras M. The base excision repair pathway. Trends Biochem. Sci. 20:1995;391-397.
52. Singer B., Hang B. What structural features determine repair enzyme specificity and mechanism in chemically modified DNA? Chem. Res. Toxicol. 10:1997;713-732.
53. Singer M.F. Highly repeated sequences in mammalian genomes. Int. Rev. Cytol. 76:1982;67-112.
54. Smale S.T. Transcription initiation from TATA-less promoters within eukaryotic protein-coding genes. Biochim. Biophys. Acta. 1351:1997;73-88.
55. Srivastava D.K., Berg B.J., Prasad R., Molina J.T., Beard W.A., Tomkinson A.E., Wilson S.H. Mammalian abasic site base excision repair. Identification of the reaction sequence and rate-determining steps. J. Biol. Chem. 273:1998;21203-21209.
56. Tommasi S., Pfeifer G.P. Constitutive protection of E2F recognition sequences in the human thymidine kinase promoter during cell cycle progression. J. Biol. Chem. 272:1997;30483-30490.
57. Tommasi S., Pfeifer G.P. In vivo structure of the human cdc2 promoter: release of a p130-E2F-4 complex from sequences immediately upstream of the transcription initiation site coincides with induction of cdc2 expression. Mol. Cell Biol. 15:1995;6901-6913.
58. Tommasi S., Pfeifer G.P. In vivo structure of two divergent promoters at the human PCNA locus. Synthesis of antisense RNA and S phase-dependent binding of E2F complexes in intron 1. J. Biol. Chem. 274:1999;27829-27838.
59. Vickers M.A., Vyas P., Harris P.C., Simmons D.L., Higgs D.R. Structure of the human 3-methyladenine DNA glycosylase gene and localization close to the 16p telomere. Proc. Natl. Acad. Sci. U. S. A. 90:1993;3437-3441.
60. Vyas P., Vickers M.A., Simmons D.L., Ayyub H., Craddock C.F., Higgs D.R. Cis-Acting sequences regulating expression of the human a-globin cluster lie within constitutively open chromatin. Cell. 69:1992;781-793.
61. Weinberg R.A. The retinoblastoma protein and cell cycle. Cell. 81:1995;323-330.
62. Ye N., Holmquist G.P., O'Connor T.R. Heterogeneous repair of N-methylpurines in normal human cells at the nucleotide level. J. Mol. Biol. 284:1998;269-285.