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Volumn 7, Issue 3, 2003, Pages 343-362

Peripheral tachykinin receptors as potential therapeutic targets in visceral diseases

Author keywords

Asthma; Bladder hyperreflexia; Cancer; Cough; Cytotoxicity; HIV; Irritable bowel syndrome (IBS); Nephrotoxicity; Neurokinin A (NKA); Neurokinin B (NKB); NK 1; NK 2; NK 3; Pancreatitis; Pre eclampsia; Substance P (SP); Tachykinin (TK)

Indexed keywords

2 BENZHYDRYL 3 (2 METHOXYBENZYLAMINO) 1 AZABICYCLO[2.2.2]OCTANE; 3 (2 METHOXY 5 TRIFLUOROMETHOXYBENZYLAMINO) 2 PHENYLPIPERIDINE; 3 (2 METHOXYBENZYLAMINO) 2 PHENYLPIPERIDINE; 3 [3,5 BIS(TRIFLUOROMETHYL)BENZYLOXY] 2 PHENYLPIPERIDINE; ANTINEOPLASTIC AGENT; ANTITUSSIVE AGENT; CP 11974; FK 224; GR 159897; MDL 103392; MEN 11467; N BENZYL N2 [4 HYDROXY 1 [(1 METHYL 1H INDOL 3 YL)CARBONYL]PROLYL] N METHYL 3 (2 NAPHTHYL)ALANINAMIDE; NEPADUTANT; NEUROKININ 1 RECEPTOR; NEUROKININ 1 RECEPTOR ANTAGONIST; NEUROKININ 2 RECEPTOR; NEUROKININ 2 RECEPTOR ANTAGONIST; NEUROKININ 3 RECEPTOR; NEUROKININ 3 RECEPTOR ANTAGONIST; NK 5807; NOLPITANTIUM; OSANETANT; SAREDUTANT; SB 235375; SB 235575; SSR 146977; TACHYKININ RECEPTOR; TACHYKININ RECEPTOR ANTAGONIST; TAK 637; TALNETANT; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 0038040876     PISSN: 14728222     EISSN: None     Source Type: Journal    
DOI: 10.1517/14728222.7.3.343     Document Type: Review
Times cited : (55)

References (222)
  • 1
    • 0029954092 scopus 로고    scopus 로고
    • Inflammatory pain hypersensitivity mediated by phenotypic switch in myelinated primary sensory neurons
    • NEUMANN S, DOUBELL TP, LESLIE T, WOOLF CJ: Inflammatory pain hypersensitivity mediated by phenotypic switch in myelinated primary sensory neurons. Nature (1996) 384:360-364.
    • (1996) Nature , vol.384 , pp. 360-364
    • Neumann, S.1    Doubell, T.P.2    Leslie, T.3    Woolf, C.J.4
  • 2
    • 0034089114 scopus 로고    scopus 로고
    • Nerve growth factor-induced phenotypic switch in guinea-pig airway sensory neurons
    • HUNTER DD, MYERS AC, UNDEM BJ: Nerve growth factor-induced phenotypic switch in guinea-pig airway sensory neurons. Am. J. Respir. Crit. Care Med. (2000) 161:1985-1990.
    • (2000) Am. J. Respir. Crit. Care Med. , vol.161 , pp. 1985-1990
    • Hunter, D.D.1    Myers, A.C.2    Undem, B.J.3
  • 3
    • 0036082623 scopus 로고    scopus 로고
    • Allergic inflammation-induced neuropeptide production in rapidly adapting afferent nerves in guniea-pig airways
    • MYERS AC, KAJEKAR R, UNDEM BJ: Allergic inflammation-induced neuropeptide production in rapidly adapting afferent nerves in guniea-pig airways. Am. J. Physiol. Lung Mol. Physiol. (2002) 282:L775-L781.
    • (2002) Am. J. Physiol. Lung Mol. Physiol. , vol.282
    • Myers, A.C.1    Kajekar, R.2    Undem, B.J.3
  • 4
    • 0037090616 scopus 로고    scopus 로고
    • Expression of tachykinins in non-nociceptive vagal afferent neurons during respiratory viral infection in guinea-pigs
    • CARR MJ, HUNTER DD, JACOBY DB, UNDEM BJ: Expression of tachykinins in non-nociceptive vagal afferent neurons during respiratory viral infection in guinea-pigs. Am. J. Respir. Crit. Care Med. (2002) 165:1071-1075.
    • (2002) Am. J. Respir. Crit. Care Med. , vol.165 , pp. 1071-1075
    • Carr, M.J.1    Hunter, D.D.2    Jacoby, D.B.3    Undem, B.J.4
  • 5
    • 0035988860 scopus 로고    scopus 로고
    • Tachykinin receptor antagonists in irritable bowel syndrome
    • LECCI A, VALENTI C, MAGGI CA: Tachykinin receptor antagonists in irritable bowel syndrome. Curr. Opin. Invest. Drugs (2002) 3:589-601.
    • (2002) Curr. Opin. Invest. Drugs , vol.3 , pp. 589-601
    • Lecci, A.1    Valenti, C.2    Maggi, C.A.3
  • 7
    • 0026323939 scopus 로고
    • Cytokine regulation of substance P expression in sympathetic neurons
    • FREIDIN M, KESSLER JA: Cytokine regulation of substance P expression in sympathetic neurons. Proc. Natl. Acad. Sci. USA (1991) 88:3200-3203.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 3200-3203
    • Freidin, M.1    Kessler, J.A.2
  • 8
    • 0030925228 scopus 로고    scopus 로고
    • Regulation of neuropeptide expression in sympathetic neurons. Paracrine and retrograde influences
    • ZIGMOND RE, SUN Y: Regulation of neuropeptide expression in sympathetic neurons. Paracrine and retrograde influences. Ann. NY Acad. Sci. (1997) 814:181-197.
    • (1997) Ann. N.Y. Acad. Sci. , vol.814 , pp. 181-197
    • Zigmond, R.E.1    Sun, Y.2
  • 9
    • 0032494281 scopus 로고    scopus 로고
    • Synaptic organization of neuropeptide-containing preganglionic boutons in lumbar sympathetic ganglia of guinea-pigs
    • MURPHY SM, MATTHEW SE, RODGERS HF, LITURI DT, GIBBINS IL: Synaptic organization of neuropeptide-containing preganglionic boutons in lumbar sympathetic ganglia of guinea-pigs. J. Comp. Neurol. (1998) 398:551-567.
    • (1998) J. Comp. Neurol. , vol.398 , pp. 551-567
    • Murphy, S.M.1    Matthew, S.E.2    Rodgers, H.F.3    Lituri, D.T.4    Gibbins, I.L.5
  • 10
    • 0021235619 scopus 로고
    • The immunohistochemical localization of nine peptides in the sacral parasympathetic nucleus and the dorsal gray commissure in rat spinal cord
    • SASEK CA, SEYBOLD VS, ELDE RP: The immunohistochemical localization of nine peptides in the sacral parasympathetic nucleus and the dorsal gray commissure in rat spinal cord. Neuroscience (1984) 12:855-873.
    • (1984) Neuroscience , vol.12 , pp. 855-873
    • Sasek, C.A.1    Seybold, V.S.2    Elde, R.P.3
  • 11
    • 0030791418 scopus 로고    scopus 로고
    • The effects of tachykinins on inflammatory and immune cells
    • MAGGI CA: The effects of tachykinins on inflammatory and immune cells. Regul. Pept. (1997) 70:75-90.
    • (1997) Regul. Pept. , vol.70 , pp. 75-90
    • Maggi, C.A.1
  • 12
    • 0035840829 scopus 로고    scopus 로고
    • Airway inflammation and tachykinins: Prospects for the development of tachykinin receptor antagonists
    • JOOS GF, DE SWERT KO, PAUWELS RA: Airway inflammation and tachykinins: prospects for the development of tachykinin receptor antagonists. Eur. J. Pharmacol. (2001) 429:239-250.
    • (2001) Eur. J. Pharmacol. , vol.429 , pp. 239-250
    • Joos, G.F.1    De Swert, K.O.2    Pauwels, R.A.3
  • 14
    • 0034332431 scopus 로고    scopus 로고
    • Hemokinin is a hematopoietic-specific tachykinin that regulates B lymphopoiesis
    • ZHANG Y, LU L, FURLONGER C, WU GE, PAIGE CJ: Hemokinin is a hematopoietic-specific tachykinin that regulates B lymphopoiesis. Nat. Immunol. (2000) 1:392-397.
    • (2000) Nat. Immunol. , vol.1 , pp. 392-397
    • Zhang, Y.1    Lu, L.2    Furlonger, C.3    Wu, G.E.4    Paige, C.J.5
  • 15
    • 0026583691 scopus 로고
    • Substance P like-immunoreactivity release from enterochromaffin cells of rat caecum mucosa. Inhibition by serotonin and calcium-free medium
    • SIMON C, PORTALIER P, CHAMOIN MC, TERNAUX JP: Substance P like-immunoreactivity release from enterochromaffin cells of rat caecum. mucosa. Inhibition by serotonin and calcium-free medium. Neurochem. Int. (1992) 20:529-536.
    • (1992) Neurochem. Int. , vol.20 , pp. 529-536
    • Simon, C.1    Portalier, P.2    Chamoin, M.C.3    Ternaux, J.P.4
  • 17
    • 0035918061 scopus 로고    scopus 로고
    • A regulatory role for neurokinin B in placental physiology and pre-eclampsia
    • PAGE NM,WOODS RJ, LOWRY PJ: A regulatory role for neurokinin B in placental physiology and pre-eclampsia. Regul. Pept. (2001) 98:97-104.
    • (2001) Regul. Pept. , vol.98 , pp. 97-104
    • Page, N.M.1    Woods, R.J.2    Lowry, P.J.3
  • 18
    • 0035839255 scopus 로고    scopus 로고
    • Expression of preprotachykinin-B, the gene that encodes neurokinin B, in rat uterus
    • PINTO FM, CINTADO CG, DEVILLIER P, CANDENAS ML: Expression of preprotachykinin-B, the gene that encodes neurokinin B, in rat uterus. Eur. J. Pharmacol. (2001) 425:R1-R2.
    • (2001) Eur. J. Pharmacol. , vol.425
    • Pinto, F.M.1    Cintado, C.G.2    Devillier, P.3    Candenas, M.L.4
  • 19
    • 0036094232 scopus 로고    scopus 로고
    • Substance P-induced preprotachykinin-α mRNA, neutral endopeptidase mRNA and substance P in cultured normal fibroblast
    • BAE SJ, MATSUNAGA Y, TAKENAKA M et al.: Substance P-induced preprotachykinin-α mRNA, neutral endopeptidase mRNA and substance P in cultured normal fibroblast. Int. Arch. Allergy Immunol. (2002) 127:316-321.
    • (2002) Int. Arch. Allergy Immunol. , vol.127 , pp. 316-321
    • Bae, S.J.1    Matsunaga, Y.2    Takenaka, M.3
  • 20
    • 0035206680 scopus 로고    scopus 로고
    • Endothelin-1 increases cholinergic nerve-mediated contraction of human bronchi via tachykinin synthesis induction
    • D'AGOSTINO B, ADVENIER C, FALCIANI M et al.: Endothelin-1 increases cholinergic nerve-mediated contraction of human bronchi via tachykinin synthesis induction. Br. J. Pharmacol. (2001) 134:1447-1454.
    • (2001) Br. J. Pharmacol. , vol.134 , pp. 1447-1454
    • D'Agostino, B.1    Advenier, C.2    Falciani, M.3
  • 21
    • 0037215591 scopus 로고    scopus 로고
    • Airway smooth muscle cells express functional neurokinin-1 receptors and the nerve-derived preprotachykinin-A gene
    • MAGHNI K, MICHOUD MC, ALLES M et al.: Airway smooth muscle cells express functional neurokinin-1 receptors and the nerve-derived preprotachykinin-A gene. Am. J. Respir. Cell Mol. Biol. (2003) 28:103-110.
    • (2003) Am. J. Respir. Cell Mol. Biol. , vol.28 , pp. 103-110
    • Maghni, K.1    Michoud, M.C.2    Alles, M.3
  • 22
    • 0026503927 scopus 로고
    • Differential activation of intracellular effector by two isoforms of human neurokinin-1 receptor
    • FONG TM, ANDERSON SA, YU H, HUANG RR, STRADER. CD: Differential activation of intracellular effector by two isoforms of human neurokinin-1 receptor. Mol. Pharmacol. (1992) 41:24-30.
    • (1992) Mol. Pharmacol. , vol.41 , pp. 24-30
    • Fong, T.M.1    Anderson, S.A.2    Yu, H.3    Huang, R.R.4    Strader, C.D.5
  • 23
    • 0027390581 scopus 로고
    • Biochemical characterization of two different forms of the substance P receptor in rat submaxillary gland
    • KAGE R, LEEMAN SE, BOYD ND: Biochemical characterization of two different forms of the substance P receptor in rat submaxillary gland. J. Neurochem. (1993) 60:347-351.
    • (1993) J. Neurochem. , vol.60 , pp. 347-351
    • Kage, R.1    Leeman, S.E.2    Boyd, N.D.3
  • 24
    • 0037032595 scopus 로고    scopus 로고
    • Identification of a tachykinin NK2 receptor splice variant and its expression in human and rat tissues
    • CANDENAS ML, CINTADO CG, PENNEFATHER JN et al.: Identification of a tachykinin NK2 receptor splice variant and its expression in human and rat tissues. Life Sci. (2002) 72:269-277.
    • (2002) Life Sci. , vol.72 , pp. 269-277
    • Candenas, M.L.1    Cintado, C.G.2    Pennefather, J.N.3
  • 25
    • 0037082358 scopus 로고    scopus 로고
    • The human tachykinin NK1 (short form) and tachykinin NK4 receptor: A reappraisal
    • PAGE NM, BELL NJ: The human tachykinin NK1 (short form) and tachykinin NK4 receptor: a reappraisal. Eur. J. Pharmacol. (2002) 437:27-30.
    • (2002) Eur. J. Pharmacol. , vol.437 , pp. 27-30
    • Page, N.M.1    Bell, N.J.2
  • 26
    • 0035026279 scopus 로고    scopus 로고
    • Protein kinase C-mediated desensitization of the neurokinin-1 receptor
    • DERY O, DEFEA KA, BUNNETT NW: Protein kinase C-mediated desensitization of the neurokinin-1 receptor. Am. J Physiol. Cell. Physiol. (2001) 280:C1097-C1106.
    • (2001) Am. J Physiol. Cell. Physiol. , vol.280
    • Dery, O.1    Defea, K.A.2    Bunnett, N.W.3
  • 27
    • 0035873496 scopus 로고    scopus 로고
    • Differential contribution of substance P and neurokinin A to spinal cord neurokinin-1 receptor signaling in the rat
    • TRAFTON JA, ABBADIE C, BASBAUM AI: Differential contribution of substance P and neurokinin A to spinal cord neurokinin-1 receptor signaling in the rat. J. Neurosci. (2001) 21:3656-3664.
    • (2001) J. Neurosci. , vol.21 , pp. 3656-3664
    • Trafton, J.A.1    Abbadie, C.2    Basbaum, A.I.3
  • 28
    • 0036157658 scopus 로고    scopus 로고
    • Pharmacological profile of the novel mammalian tachykinin hemokinin 1
    • BELLUCCI F, CARINI F, CATALANI C et al.: Pharmacological profile of the novel mammalian tachykinin hemokinin 1. Br. J. Pharmacol. (2002) 135:266-274.
    • (2002) Br. J. Pharmacol. , vol.135 , pp. 266-274
    • Bellucci, F.1    Carini, F.2    Catalani, C.3
  • 29
    • 0033457351 scopus 로고    scopus 로고
    • Discovery of the anti-depressant and anti-emetic efficacy of substance P receptor (NK1) antagonists
    • RUPNIAK NMJ, KRAMER MS: Discovery of the anti-depressant and anti-emetic efficacy of substance P receptor (NK1) antagonists. Trends Pharmacol. Sci. (1999) 20:485-490.
    • (1999) Trends Pharmacol. Sci. , vol.20 , pp. 485-490
    • Rupniak, N.M.J.1    Kramer, M.S.2
  • 30
    • 0036225872 scopus 로고    scopus 로고
    • Correlation of neurokinin (NK)-1 receptor occupancy in gerbil striatum with behavioral effects of NK1 antagonists
    • DUFFY RA, VARTY GB, MORGAN CA, LACHOWICZ JE: Correlation of neurokinin (NK)-1 receptor occupancy in gerbil striatum with behavioral effects of NK1 antagonists. J. Pharmacol. Exp. Ther. (2002) 301:536-542.
    • (2002) J. Pharmacol. Exp. Ther. , vol.301 , pp. 536-542
    • Duffy, R.A.1    Varty, G.B.2    Morgan, C.A.3    Lachowicz, J.E.4
  • 31
    • 0027092318 scopus 로고
    • Molecular basis for the species selectivity of neurokinin-1 receptor antagonists CP96345 and RP67580
    • FONG TM, YU H, STRADER CD: Molecular basis for the species selectivity of neurokinin-1 receptor antagonists CP96345 and RP67580. J. Biol. Chem. (1992) 267:25668-25671.
    • (1992) J. Biol. Chem. , vol.267 , pp. 25668-25671
    • Fong, T.M.1    Yu, H.2    Strader, C.D.3
  • 32
    • 0027954458 scopus 로고
    • The species selectivity of chemically distinct tachykinin nonpeptide antagonists is dependent on common divergent residues of the rat and human neurokinin-1 receptors
    • JENSEN CJ, GERARD NP, SCHWARTZ TW, GETHER U: The species selectivity of chemically distinct tachykinin nonpeptide antagonists is dependent on common divergent residues of the rat and human neurokinin-1 receptors. Mol. Pharmacol. (1994) 45:294-299.
    • (1994) Mol. Pharmacol. , vol.45 , pp. 294-299
    • Jensen, C.J.1    Gerard, N.P.2    Schwartz, T.W.3    Gether, U.4
  • 33
    • 0034937042 scopus 로고    scopus 로고
    • Tachykinin receptor antagonists for asthma and COPD
    • ROGERS DF: Tachykinin receptor antagonists for asthma and COPD. Expert Opin. Ther. Patents (2001) 11:1097-1121.
    • (2001) Expert Opin. Ther. Patents , vol.11 , pp. 1097-1121
    • Rogers, D.F.1
  • 34
    • 0034023973 scopus 로고    scopus 로고
    • Respiratory actions of tachykinins in the nucleus of the solitary tract: Characterization of receptors using selective agonists and antagonists
    • MAZZONE SB, GERAGHTY DP: Respiratory actions of tachykinins in the nucleus of the solitary tract: characterization of receptors using selective agonists and antagonists. Br. J. Pharmacol. (2000) 129:1121-1131.
    • (2000) Br. J. Pharmacol. , vol.129 , pp. 1121-1131
    • Mazzone, S.B.1    Geraghty, D.P.2
  • 35
    • 0034053463 scopus 로고    scopus 로고
    • Role of nitric oxide and septide-insensitive NK1 receptors in bronchoconstriction induced by aereosolized neurokinin A in guinea-pigs
    • RICCIARDOLO FLM, TREVISANI M, GEPPETTI P, NADEL JA, AMADESI S, BERTRAND C: Role of nitric oxide and septide-insensitive NK1 receptors in bronchoconstriction induced by aereosolized neurokinin A in guinea-pigs. Br. J. Pharmacol. (2000) 129:915-920.
    • (2000) Br. J. Pharmacol. , vol.129 , pp. 915-920
    • Ricciardolo, F.L.M.1    Trevisani, M.2    Geppetti, P.3    Nadel, J.A.4    Amadesi, S.5    Bertrand, C.6
  • 37
    • 0034744445 scopus 로고    scopus 로고
    • NK1 receptor stimulation causes contraction and inositol phosphate increase in medium-size human isolated bronchi
    • AMADESI S, MOREAU J, TOGNETTO M et al.: NK1 receptor stimulation causes contraction and inositol phosphate increase in medium-size human isolated bronchi. Am. J. Respir. Crit. Care Med. (2001) 163:1026-1211.
    • (2001) Am. J. Respir. Crit. Care Med. , vol.163 , pp. 1026-1211
    • Amadesi, S.1    Moreau, J.2    Tognetto, M.3
  • 38
    • 0032588091 scopus 로고    scopus 로고
    • Interleukin-1β-induced hyperresponsiveness to Sar9,Met(O2)11-substance P in isolated human bronchi
    • BARCHASZ E, NALINE E, MOLIMARD, M et al.: Interleukin-1β-induced hyperresponsiveness to Sar9,Met(O2 11-substance P in isolated human bronchi. Eur. J. Pharmacol. (1999) 379:87-95.
    • (1999) Eur. J. Pharmacol. , vol.379 , pp. 87-95
    • Barchasz, E.1    Naline, E.2    Molimard, M.3
  • 39
    • 0031815845 scopus 로고    scopus 로고
    • The effect of the NK2 tachykinin receptor antagonist SR 48968 (saredutant) on neurokinin A-induced bronchoconstriction in asthmatics
    • VAN SCHOOR J, JOOS GF, CHASSON BL, BROUARD RJ, PAUWELS RA: The effect of the NK2 tachykinin receptor antagonist SR 48968 (saredutant) on neurokinin A-induced bronchoconstriction in asthmatics. Eur. Respir. J. (1998) 12:17-23.
    • (1998) Eur. Respir. J. , vol.12 , pp. 17-23
    • Van Schoor, J.1    Joos, G.F.2    Chasson, B.L.3    Brouard, R.J.4    Pauwels, R.A.5
  • 40
    • 0030460705 scopus 로고    scopus 로고
    • Protective effect of substance P on permeability of airway epithelial cells in culture
    • YU XY, UNDEM BJ, SPANNHAKE EW: Protective effect of substance P on permeability of airway epithelial cells in culture. Am. J. Physiol. (1996) 271:L889-L895.
    • (1996) Am. J. Physiol. , vol.271
    • Yu, X.Y.1    Undem, B.J.2    Spannhake, E.W.3
  • 41
    • 0032895597 scopus 로고    scopus 로고
    • Particulate matter initiates inflammatory cytokine release by activation of capsaicin and acid receptors in a human bronchial epithelial cell line
    • VERONESI B, OORTGIESEN M, CARTER JD, DEVLIN RB: Particulate matter initiates inflammatory cytokine release by activation of capsaicin and acid receptors in a human bronchial epithelial cell line. Toxicol. Appl. Pharmacol. (1999) 154:106-115.
    • (1999) Toxicol. Appl. Pharmacol. , vol.154 , pp. 106-115
    • Veronesi, B.1    Oortgiesen, M.2    Carter, J.D.3    Devlin, R.B.4
  • 42
    • 0034704462 scopus 로고    scopus 로고
    • Differential role of neurokinin receptors in human lymphocyte and monocyte chemotaxis
    • HOOD VC, CRUWYS SC, URBAN L, KIDD BL: Differential role of neurokinin receptors in human lymphocyte and monocyte chemotaxis. Regul. Pept. (2000) 96:17-21.
    • (2000) Regul. Pept. , vol.96 , pp. 17-21
    • Hood, V.C.1    Cruwys, S.C.2    Urban, L.3    Kidd, B.L.4
  • 43
    • 0034109173 scopus 로고    scopus 로고
    • Tachykinin activation of human monocytes from patients with interstitial lung disease, healthy smokers, or healthy volunteers
    • BRUNELLESCHI S, NICALI R, LAVAGNO L et al.: Tachykinin activation of human monocytes from patients with interstitial lung disease, healthy smokers, or healthy volunteers. Neuropeptides (2000) 34:45-50.
    • (2000) Neuropeptides , vol.34 , pp. 45-50
    • Brunelleschi, S.1    Nicali, R.2    Lavagno, L.3
  • 49
    • 0029658571 scopus 로고    scopus 로고
    • NK1 receptor antagonist CP-99994 inhibits cigarette smoke-induced neutrophil and eosinophil adhesion in rat tracheal venules
    • BALUK P, BERTRAND C, GEPPETTI P, MCDONALD DM, NADEL JA: NK1 receptor antagonist CP-99994 inhibits cigarette smoke-induced neutrophil and eosinophil adhesion in rat tracheal venules. Exp. Lung Res. (1996) 22:409-418.
    • (1996) Exp. Lung Res. , vol.22 , pp. 409-418
    • Baluk, P.1    Bertrand, C.2    Geppetti, P.3    Mcdonald, D.M.4    Nadel, J.A.5
  • 50
    • 0035839270 scopus 로고    scopus 로고
    • Alleviation of wood smoke-induced lung injury by tachykinin receptor antagonist and hydroxyl radical scavenger in guniea-pigs
    • LIN YS, HO CY, TANG GJ, KOU YR: Alleviation of wood smoke-induced lung injury by tachykinin receptor antagonist and hydroxyl radical scavenger in guniea-pigs. Eur. J. Pharmacol. (2001) 425:141-148.
    • (2001) Eur. J. Pharmacol. , vol.425 , pp. 141-148
    • Lin, Y.S.1    Ho, C.Y.2    Tang, G.J.3    Kou, Y.R.4
  • 51
    • 0032586704 scopus 로고    scopus 로고
    • Involvement of tachykinin NK1 receptor in the development of allergen-induced airway hyperreactivity and airway inflammation in conscious, unrestrained guinea-pigs
    • SCHUILING M, ZUIDHOF AB, ZAAGSMA J, MEURS H: Involvement of tachykinin NK1 receptor in the development of allergen-induced airway hyperreactivity and airway inflammation in conscious, unrestrained guinea-pigs. Am. J. Respir. Crit. Care Med. (1999) 159:423-430.
    • (1999) Am. J. Respir. Crit. Care Med. , vol.159 , pp. 423-430
    • Schuiling, M.1    Zuidhof, A.B.2    Zaagsma, J.3    Meurs, H.4
  • 52
    • 0030936717 scopus 로고    scopus 로고
    • Esophageal stimulation by hydrochloric acid causes neurogenic inflammation in the airways in guinea-pigs
    • HAMAMOTO J, KOHROGI H, KAWANO O et al.: Esophageal stimulation by hydrochloric acid causes neurogenic inflammation in the airways in guinea-pigs. J. Appl. Physiol. (1997) 82:738-745.
    • (1997) J. Appl. Physiol. , vol.82 , pp. 738-745
    • Hamamoto, J.1    Kohrogi, H.2    Kawano, O.3
  • 53
    • 0035804039 scopus 로고    scopus 로고
    • The role of substance P release in the lung with esophageal acid
    • KOHOROGI H, HAMAMOTO J, KAWANO O et al.: The role of substance P release in the lung with esophageal acid. Am. J. Med. (2001) 111(Suppl. 8A):S25-S30.
    • (2001) Am. J. Med. , vol.111 , Issue.SUPPL. 8A
    • Kohorogi, H.1    Hamamoto, J.2    Kawano, O.3
  • 55
    • 0029661797 scopus 로고    scopus 로고
    • Involvement of tachykinin NK1 and NK2 receptors in substance P-induced microvascular leakage hypersensitivity and airway hyperresponsiveness in guinea-pigs
    • BOICHOT E, BIYAH K, GERMAIN N, EMONDS-ALT X, LAGENTE V, ADVENIER C: Involvement of tachykinin NK1 and NK2 receptors in substance P-induced microvascular leakage hypersensitivity and airway hyperresponsiveness in guinea-pigs. Eur. Resp. J. (1996) 9:1445-1450.
    • (1996) Eur. Resp. J. , vol.9 , pp. 1445-1450
    • Boichot, E.1    Biyah, K.2    Germain, N.3    Emonds-Alt, X.4    Lagente, V.5    Advenier, C.6
  • 56
    • 0032491473 scopus 로고    scopus 로고
    • Acetylcholine and tachykinin receptor antagonists attenuate wood smoke-induced bronchoconstriction in guinea-pigs
    • HSU TH, LAI YL, KOU YR: Acetylcholine and tachykinin receptor antagonists attenuate wood smoke-induced bronchoconstriction in guinea-pigs. Eur. J. Pharmacol. (1998) 360:175-183.
    • (1998) Eur. J. Pharmacol. , vol.360 , pp. 175-183
    • Hsu, T.H.1    Lai, Y.L.2    Kou, Y.R.3
  • 57
    • 0031596479 scopus 로고    scopus 로고
    • Effects of tachykinin NK1 receptor antagonists on vagal hyperreactivity and neuronal muscarinic receptor function in antigen-challenged guinea-pigs
    • COSTELLO RW, FRYER AD, BELMONTE KE, JACOBY DB: Effects of tachykinin NK1 receptor antagonists on vagal hyperreactivity and neuronal muscarinic receptor function in antigen-challenged guinea-pigs. Br. J. Pharmacol. (1998) 124:267-276.
    • (1998) Br. J. Pharmacol. , vol.124 , pp. 267-276
    • Costello, R.W.1    Fryer, A.D.2    Belmonte, K.E.3    Jacoby, D.B.4
  • 59
    • 0033622154 scopus 로고    scopus 로고
    • Neurokinin-1 receptor antagonist inhibits short-term sulfuric acid-induced airway hyperresponsiveness in sensitized guinea-pigs
    • TERAMOTO S, TANAKA H, KANEKO S, ABE S: Neurokinin-1 receptor antagonist inhibits short-term sulfuric acid-induced airway hyperresponsiveness in sensitized guinea-pigs. Int. Arch. Allergy Immunol. (2000) 121:53-56.
    • (2000) Int. Arch. Allergy Immunol. , vol.121 , pp. 53-56
    • Teramoto, S.1    Tanaka, H.2    Kaneko, S.3    Abe, S.4
  • 60
    • 0037192557 scopus 로고    scopus 로고
    • Role of tachykinins in Sephadex-induced airway hyperreactivity and inflammation in guinea-pigs
    • TRAMONTANA M, SANTICIOLI P. GIULIANI S et al.: Role of tachykinins in Sephadex-induced airway hyperreactivity and inflammation in guinea-pigs. Eur. J. Pharmacol. (2002) 439:149-158.
    • (2002) Eur. J. Pharmacol. , vol.439 , pp. 149-158
    • Tramontana, M.1    Santicioli, P.2    Giuliani, S.3
  • 62
    • 9044235778 scopus 로고    scopus 로고
    • A neurokinin-1 receptor antagonist improves exercise-induced airway narrowing in asthmatic patients
    • ICHINOSE M, MIURA M, YAMAUCHI H et al.: A neurokinin-1 receptor antagonist improves exercise-induced airway narrowing in asthmatic patients. Am. J. Respir. Crit. Care Med. (1996) 153:936-941.
    • (1996) Am. J. Respir. Crit. Care Med. , vol.153 , pp. 936-941
    • Ichinose, M.1    Miura, M.2    Yamauchi, H.3
  • 63
    • 0028990953 scopus 로고
    • Effect of an NK1 receptor antagonist (CP-99,994) on hypertonic saline-induced bronchoconstriction and cough in asthmatic subjects
    • FAHY JV, WONG HH, GEPPETTI P et al.: Effect of an NK1 receptor antagonist (CP-99,994) on hypertonic saline-induced bronchoconstriction and cough in asthmatic subjects. Am. J. Respir. Crit. Care Med. (1995) 152:879-884.
    • (1995) Am. J. Respir. Crit. Care Med. , vol.152 , pp. 879-884
    • Fahy, J.V.1    Wong, H.H.2    Geppetti, P.3
  • 64
    • 0036569771 scopus 로고    scopus 로고
    • Assessment of microvascular leakage via sputum induction. The role of substance P and neurokinin A in patients with asthma
    • VAN RENSEN ELJ, HIEMSTRA PS, RABE KF, STERK PJ: Assessment of microvascular leakage via sputum induction. The role of substance P and neurokinin A in patients with asthma. Am. J. Respir. Crit. Care Med. (2002) 165:1275-1279.
    • (2002) Am. J. Respir. Crit. Care Med. , vol.165 , pp. 1275-1279
    • Van Rensen, E.L.J.1    Hiemstra, P.S.2    Rabe, K.F.3    Sterk, P.J.4
  • 65
    • 0033710731 scopus 로고    scopus 로고
    • NK1 receptor desensitization and neutral endopeptidase terminate SP-induced pancreatic plasma extravasation
    • MAA J, GRADY EF, KIM EH et al.: NK1 receptor desensitization and neutral endopeptidase terminate SP-induced pancreatic plasma extravasation. Am. J. Physiol. Gastrointest. Liver Physiol. (2000) 279:G726-G732.
    • (2000) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.279
    • Maa, J.1    Grady, E.F.2    Kim, E.H.3
  • 67
    • 0028888686 scopus 로고
    • Tachykinin regulation of airway smooth muscle proliferation
    • NOVERAL JP, GRUNSTEIN MM: Tachykinin regulation of airway smooth muscle proliferation. Am. J. Physiol. (1995) 269:L339-L343.
    • (1995) Am. J. Physiol. , vol.269
    • Noveral, J.P.1    Grunstein, M.M.2
  • 68
    • 0036830093 scopus 로고    scopus 로고
    • Substance P-induced activation of P42/44 mitogen-activated protein kinase associated with cell proliferation in human tracheal smooth muscle cells
    • YANG CM, HSIAO LD, CHIEN CS, LIN CC, LUO SF, WANG CC: Substance P-induced activation of P42/44 mitogen-activated protein kinase associated with cell proliferation in human tracheal smooth muscle cells. Cell Signal (2002) 14:913-923.
    • (2002) Cell Signal , vol.14 , pp. 913-923
    • Yang, C.M.1    Hsiao, L.D.2    Chien, C.S.3    Lin, C.C.4    Luo, S.F.5    Wang, C.C.6
  • 69
    • 0030812744 scopus 로고    scopus 로고
    • Bronchoconstrictor and respiratory effects of neurokinin A in dogs
    • SHERWOOD JE, MAUSER PJ, CHAPMAN RW: Bronchoconstrictor and respiratory effects of neurokinin A in dogs. J. Pharmacol. Exp. Ther. (1997) 283:788-793.
    • (1997) J. Pharmacol. Exp. Ther. , vol.283 , pp. 788-793
    • Sherwood, J.E.1    Mauser, P.J.2    Chapman, R.W.3
  • 70
    • 0034640190 scopus 로고    scopus 로고
    • Tachykinin NK2 receptors facilitate acetylcholine release from guinea-pig isolated trachea
    • D'AGOSTINO G, ERBELDING D, KILBINGER H: Tachykinin NK2 receptors facilitate acetylcholine release from guinea-pig isolated trachea. Eur. J. Pharmacol. (2000) 396:29-32.
    • (2000) Eur. J. Pharmacol. , vol.396 , pp. 29-32
    • D'Agostino, G.1    Erbelding, D.2    Kilbinger, H.3
  • 71
    • 0034786104 scopus 로고    scopus 로고
    • Nitric oxide is generated in smooth muscle layer by neurokinin A and counteracts constriction in guinea-pig airway
    • IMASAKI T, KOBAYASHI H, HATAISHI R, HAYASHI I, TOMITA T, MAJIMA M: Nitric oxide is generated in smooth muscle layer by neurokinin A and counteracts constriction in guinea-pig airway. Nitric Oxide (2001) 5:465-474.
    • (2001) Nitric Oxide , vol.5 , pp. 465-474
    • Imasaki, T.1    Kobayashi, H.2    Hataishi, R.3    Hayashi, I.4    Tomita, T.5    Majima, M.6
  • 72
    • 0031901881 scopus 로고    scopus 로고
    • Characterization of the antibronchoconstrictor activity of MEN11420, a tachykinin NK2 receptor antagonist, in guinea-pigs
    • TRAMONTANA M, PATACCHINI R, GIULIANI S et al.: Characterization of the antibronchoconstrictor activity of MEN11420, a tachykinin NK2 receptor antagonist, in guinea-pigs. Eur. J. Pharmacol. (1998) 352:279-288.
    • (1998) Eur. J. Pharmacol. , vol.352 , pp. 279-288
    • Tramontana, M.1    Patacchini, R.2    Giuliani, S.3
  • 73
    • 0033082680 scopus 로고    scopus 로고
    • NK2 receptor mediated contraction in monkey, gainea-pig and human airway smooth muscle
    • RIZZO CA, VALENTINE AF, EGAN RW, KREUTNER W, HEY JA: NK2 receptor mediated contraction in monkey, gainea-pig and human airway smooth muscle. Neuropeptides (1999) 33:27-34.
    • (1999) Neuropeptides , vol.33 , pp. 27-34
    • Rizzo, C.A.1    Valentine, A.F.2    Egan, R.W.3    Kreutner, W.4    Hey, J.A.5
  • 76
    • 0032587310 scopus 로고    scopus 로고
    • Role of tachykinin NK2 receptor activation in the allergen-induced late asthmatic reaction, airway hyperreactivity and airway inflammatory cell influx in conscious, unrestrained guinea-pigs
    • SCHUILING M, ZUIDHOF AB, MEURS H, ZAAGSMA J: Role of tachykinin NK2 receptor activation in the allergen-induced late asthmatic reaction, airway hyperreactivity and airway inflammatory cell influx in conscious, unrestrained guinea-pigs. Br. J. Pharmacol. (1999) 127:1030-1038.
    • (1999) Br. J. Pharmacol. , vol.127 , pp. 1030-1038
    • Schuiling, M.1    Zuidhof, A.B.2    Meurs, H.3    Zaagsma, J.4
  • 77
    • 0033833851 scopus 로고    scopus 로고
    • Dichotomy between neurokinin receptor actions in modulating allergic airway responses in an animal model of helper T cell Type 2 cytokine-associated inflammation
    • MAGHNI K, TAHA R, AFIF W, QUTAYBA H, MARTIN JG: Dichotomy between neurokinin receptor actions in modulating allergic airway responses in an animal model of helper T cell Type 2 cytokine-associated inflammation. Am. J. Respir. Crit. Care Med. (2000) 162:1068-1074.
    • (2000) Am. J. Respir. Crit. Care Med. , vol.162 , pp. 1068-1074
    • Maghni, K.1    Taha, R.2    Afif, W.3    Qutayba, H.4    Martin, J.G.5
  • 78
    • 0034022224 scopus 로고    scopus 로고
    • Participation of neuropeptides in antigen-induced contraction of guinea-pig bronchi via NK2 but not NK1 receptor stimulation
    • TANPO T, NABE T, YASUI K, KAMIKI T, KOHNO S: Participation of neuropeptides in antigen-induced contraction of guinea-pig bronchi via NK2 but not NK1 receptor stimulation. Pharmacology (2000) 60:169-174.
    • (2000) Pharmacology , vol.60 , pp. 169-174
    • Tanpo, T.1    Nabe, T.2    Yasui, K.3    Kamiki, T.4    Kohno, S.5
  • 80
    • 0033984220 scopus 로고    scopus 로고
    • Airway hyperresponsiveness to cigarette smoke in ovalbumin-sensitized guinea-pigs
    • WU ZX, ZHOU D, CHEN G, LEE LY: Airway hyperresponsiveness to cigarette smoke in ovalbumin-sensitized guinea-pigs. Am. J. Respir. Crit. Care Med. (2000) 161:73-80.
    • (2000) Am. J. Respir. Crit. Care Med. , vol.161 , pp. 73-80
    • Wu, Z.X.1    Zhou, D.2    Chen, G.3    Lee, L.Y.4
  • 83
    • 0036230403 scopus 로고    scopus 로고
    • The involvement of sensory neuropeptides in rabbits sensitized and challenged to Parietaria judaica
    • D'AGOSTINO B, ADVENIER C, DE PALMA R et al.: The involvement of sensory neuropeptides in rabbits sensitized and challenged to Parietaria judaica. Clin. Exp. Allergy (2002) 32:472-479.
    • (2002) Clin. Exp. Allergy , vol.32 , pp. 472-479
    • D'Agostino, B.1    Advenier, C.2    De Palma, R.3
  • 84
    • 0027339280 scopus 로고
    • NK2 receptors mediate plasma protein extravasation in guinea-pig lower airways
    • TOUSIGNANT C, CHAN CC, GUEVREMONT D et al.: NK2 receptors mediate plasma protein extravasation in guinea-pig lower airways. Br. J. Pharmacol. (1993) 108:383-386.
    • (1993) Br. J. Pharmacol. , vol.108 , pp. 383-386
    • Tousignant, C.1    Chan, C.C.2    Guevremont, D.3
  • 85
    • 0029415366 scopus 로고
    • Involvement of NK1 and NK2 receptors in pulmonary responses elicited by non-adrenergic, non-cholinergic vagal stimulation in guinea-pigs
    • SAVOIE C, TOUSIGNANT C, RODGER IW, CHAN CC: Involvement of NK1 and NK2 receptors in pulmonary responses elicited by non-adrenergic, non-cholinergic vagal stimulation in guinea-pigs. J. Pharm. Pharmacol. (1995) 47:914-920.
    • (1995) J. Pharm. Pharmacol. , vol.47 , pp. 914-920
    • Savoie, C.1    Tousignant, C.2    Rodger, I.W.3    Chan, C.C.4
  • 86
    • 0036201134 scopus 로고    scopus 로고
    • Tachykinin via tachykinin NK2 receptor activation mediate ozone-induced increase in the permeability of tracheal mucosa in guinea-pigs
    • FU L, KANEKO T, IKEDA H et al.: Tachykinin via tachykinin NK2 receptor activation mediate ozone-induced increase in the permeability of tracheal mucosa in guinea-pigs. Br. J. Pharmacol. (2002) 135:1331-1335.
    • (2002) Br. J. Pharmacol. , vol.135 , pp. 1331-1335
    • Fu, L.1    Kaneko, T.2    Ikeda, H.3
  • 87
    • 0028845983 scopus 로고
    • Tachykinins induce gelatinase production by guinea-pig alveolar macrophages: Involvement of NK2 receptors
    • D'ORTHO MP, JARREAU PH, DELACOURT C et al.: Tachykinins induce gelatinase production by guinea-pig alveolar macrophages: involvement of NK2 receptors. Am. J. Physiol. (1995) 269:L631-L636.
    • (1995) Am. J. Physiol. , vol.269
    • D'Ortho, M.P.1    Jarreau, P.H.2    Delacourt, C.3
  • 88
    • 0030877573 scopus 로고    scopus 로고
    • Role for neurokinin-2 receptor in interleukin-5-induced airway hyperresponsiveness but not eosinophilia in guinea-pigs
    • KRANEVELD AD, NIJKAMP FP, VAN OOSTERHOUT AJ: Role for neurokinin-2 receptor in interleukin-5-induced airway hyperresponsiveness but not eosinophilia in guinea-pigs. Am. J. Respir. Crit. Care Med. (1997) 156:367-374.
    • (1997) Am. J. Respir. Crit. Care Med. , vol.156 , pp. 367-374
    • Kraneveld, A.D.1    Nijkamp, F.P.2    Van Oosterhout, A.J.3
  • 89
    • 0033972162 scopus 로고    scopus 로고
    • The distribution of neurokinin-1 and neurokinin-2 receptors in human central airways
    • MAPP CE, MIOTTO D, BRACCIONI F et al.: The distribution of neurokinin-1 and neurokinin-2 receptors in human central airways. Am. J. Respir. Crit. Care Med. (2000) 161:207-215.
    • (2000) Am. J. Respir. Crit. Care Med. , vol.161 , pp. 207-215
    • Mapp, C.E.1    Miotto, D.2    Braccioni, F.3
  • 91
    • 0030863209 scopus 로고    scopus 로고
    • Histamine release from human bronchoalveolar lavage mast cells by neurokinin A
    • CROSS LG, HEANY LG, ENNIS M: Histamine release from human bronchoalveolar lavage mast cells by neurokinin A. Inflamm. Res. (1997) 46:306-309.
    • (1997) Inflamm. Res. , vol.46 , pp. 306-309
    • Cross, L.G.1    Heany, L.G.2    Ennis, M.3
  • 92
    • 0033961191 scopus 로고    scopus 로고
    • Sensory neuropeptides induce histamine release from bronchoalveolar lavage cells in both nonasthmatic coughers and cough variant asthmatics
    • FORSYTE P, MCGARVEY LP, HEANEY LG, MACMAHON J, ENNIS M: Sensory neuropeptides induce histamine release from bronchoalveolar lavage cells in both nonasthmatic coughers and cough variant asthmatics. Clin. Exp. Alllergy (2000) 30:225-232.
    • (2000) Clin. Exp. Alllergy , vol.30 , pp. 225-232
    • Forsyte, P.1    Mcgarvey, L.P.2    Heaney, L.G.3    Macmahon, J.4    Ennis, M.5
  • 93
    • 0027142040 scopus 로고
    • Effect of oral terfenadine on bronchoconstrictor response to inhaled neurokinin A and histamine in asthmatic subjects
    • CRIMI N, OLIVIERI R, POLOSA R et al.: Effect of oral terfenadine on bronchoconstrictor response to inhaled neurokinin A and histamine in asthmatic subjects. Eur. Respir. J. (1993) 6:1462-1467.
    • (1993) Eur. Respir. J. , vol.6 , pp. 1462-1467
    • Crimi, N.1    Olivieri, R.2    Polosa, R.3
  • 94
    • 0033964515 scopus 로고    scopus 로고
    • Antigen inhalation unmasks NK2 tachykinin receptor-mediated responses in vagal afferents
    • MOORE KA, UNDEM BJ, WEINREICH D: Antigen inhalation unmasks NK2 tachykinin receptor-mediated responses in vagal afferents. Am. J. Respir. Crit. Care Med. (2000) 161:232-236.
    • (2000) Am. J. Respir. Crit. Care Med. , vol.161 , pp. 232-236
    • Moore, K.A.1    Undem, B.J.2    Weinreich, D.3
  • 95
    • 0037501605 scopus 로고    scopus 로고
    • Are silent NK2 tachykinin receptors on primary vagal afferents really silent?
    • CORDOBA-RODRIGUEZ R, GOVER TD,WEINREICH D: Are silent NK2 tachykinin receptors on primary vagal afferents really silent? Soc. Neurosci. Abs. (1999) 25:411.
    • (1999) Soc. Neurosci. Abs. , vol.25 , pp. 411
    • Cordoba-Rodriguez, R.1    Gover, T.D.2    Weinreich, D.3
  • 96
    • 0032567915 scopus 로고    scopus 로고
    • Glucocorticoids reduce tachykinin NK2 receptor expression in bovine tracheal smooth muscle
    • KATSUNUMA T, MAK JC, BARNES PJ: Glucocorticoids reduce tachykinin NK2 receptor expression in bovine tracheal smooth muscle. Eur. J. Pharmacol. (1998) 26:99-106.
    • (1998) Eur. J. Pharmacol. , vol.26 , pp. 99-106
    • Katsunuma, T.1    Mak, J.C.2    Barnes, P.J.3
  • 99
    • 0035991294 scopus 로고    scopus 로고
    • Effect of inhaled fluticasone on bronchial responsiveness to neurokinin A in asthma
    • VAN SCHOOR J, JOOS GF, PAUWELS RA: Effect of inhaled fluticasone on bronchial responsiveness to neurokinin A in asthma. Eur. Respir. J. (2002) 19:997-1002.
    • (2002) Eur. Respir. J. , vol.19 , pp. 997-1002
    • Van Schoor, J.1    Joos, G.F.2    Pauwels, R.A.3
  • 100
    • 0002855647 scopus 로고    scopus 로고
    • The effect of the tachykinin NK2 receptor antagonist MEN11420 (nepadutant) on neurokinin A-induced bronchoconstriction in patients with asthma
    • JOOS GF, SCHELFHOUT V, VAN DE VELDE V, MAGGI CA, PAUWELS R: The effect of the tachykinin NK2 receptor antagonist MEN11420 (nepadutant) on neurokinin A-induced bronchoconstriction in patients with asthma. Am. J. Respir Crit. Care Med. (2001) 163(Suppl. 5):A628.
    • (2001) Am. J. Respir Crit. Care Med. , vol.163 , Issue.SUPPL. 5
    • Joos, G.F.1    Schelfhout, V.2    Van De Velde, V.3    Maggi, C.A.4    Pauwels, R.5
  • 101
    • 0035087148 scopus 로고    scopus 로고
    • The NK2 receptor antagonist SR48968C does not improve adenosine hyperresponsiveness and airway obstruction in allergic asthma
    • KRAAN J, VINK-KLOOSTER H, POSTMA DS: The NK2 receptor antagonist SR48968C does not improve adenosine hyperresponsiveness and airway obstruction in allergic asthma. Clin. Exp. Allergy (2001) 31:274-278.
    • (2001) Clin. Exp. Allergy , vol.31 , pp. 274-278
    • Kraan, J.1    Vink-Klooster, H.2    Postma, D.S.3
  • 102
    • 0026444911 scopus 로고
    • Protection against bradykinin-induced bronchoconstriction in asthmatic patients by neurokinin receptor antagonist
    • ICHINOSE M, NAKAJIMA N, TAKAHASHI T, YAMAUCHI H, INOUE H, TAKISHIMA T: Protection against bradykinin-induced bronchoconstriction in asthmatic patients by neurokinin receptor antagonist. Lancet (1993) 340:1248-1251.
    • (1993) Lancet , vol.340 , pp. 1248-1251
    • Ichinose, M.1    Nakajima, N.2    Takahashi, T.3    Yamauchi, H.4    Inoue, H.5    Takishima, T.6
  • 103
    • 0029951892 scopus 로고    scopus 로고
    • The effect of inhaled FK224, a tachykinin NK1 and NK2 receptor antagonist, on neurokinin A-induced bronchoconstriction
    • JOOS GF, VAN SCHOOR J, KIPS JC, PAUWELS R: The effect of inhaled FK224, a tachykinin NK1 and NK2 receptor antagonist, on neurokinin A-induced bronchoconstriction. Am. J. Respir. Crit. Care Med. (1996) 153:1781-1784.
    • (1996) Am. J. Respir. Crit. Care Med. , vol.153 , pp. 1781-1784
    • Joos, G.F.1    Van Schoor, J.2    Kips, J.C.3    Pauwels, R.4
  • 104
    • 0002855647 scopus 로고    scopus 로고
    • The effect of DNK333A: A dual tachykinin NK1/NK2 receptor antagonist on neurokinin A-induced bronchoconstriction in patients with asthma
    • JOOS G, VINCKEN W, LOUIS R, WANG J, SHAW M, PAUWELS R: The effect of DNK333A: a dual tachykinin NK1/NK2 receptor antagonist on neurokinin A-induced bronchoconstriction in patients with asthma. Am. J. Respir. Crit. Care Med. (2001) 163(Suppl. 5):A628.
    • (2001) Am. J. Respir. Crit. Care Med. , vol.163 , Issue.SUPPL. 5
    • Joos, G.1    Vincken, W.2    Louis, R.3    Wang, J.4    Shaw, M.5    Pauwels, R.6
  • 105
    • 0029134633 scopus 로고
    • Effects of two tachykinin antagonists, SR48968 and SR140333, on cough induced by citric acid in the unanaesthetized guinea-pig
    • GIRARD V, NALINE E, VILAIN P, EMONDS-ALT X, ADVENIER C: Effects of two tachykinin antagonists, SR48968 and SR140333, on cough induced by citric acid in the unanaesthetized guinea-pig. Eur. Respir. J. (1995) 8:1110-1114.
    • (1995) Eur. Respir. J. , vol.8 , pp. 1110-1114
    • Girard, V.1    Naline, E.2    Vilain, P.3    Emonds-Alt, X.4    Advenier, C.5
  • 106
    • 0027947539 scopus 로고
    • Evidence that antidromically stimulated vagal afferents activate inhibitory neurons innervating guinea-pig trachealis
    • CANNING BJ, UNDEM BJ: Evidence that antidromically stimulated vagal afferents activate inhibitory neurons innervating guinea-pig trachealis. J. Physiol. (1994) 480:613-625.
    • (1994) J. Physiol. , vol.480 , pp. 613-625
    • Canning, B.J.1    Undem, B.J.2
  • 107
    • 0031886958 scopus 로고    scopus 로고
    • Pharmacological analysis of the tachykinin receptors that mediate activation of nonadrenergic, noncholinergic relaxant nerves that innervate guinea-pig trachealis
    • CANNING BJ, FISHER A, UNDEM BJ: Pharmacological analysis of the tachykinin receptors that mediate activation of nonadrenergic, noncholinergic relaxant nerves that innervate guinea-pig trachealis. J. Pharmacol Exp. Ther. (1998) 284:370-377.
    • (1998) J. Pharmacol Exp. Ther. , vol.284 , pp. 370-377
    • Canning, B.J.1    Fisher, A.2    Undem, B.J.3
  • 109
    • 0034016842 scopus 로고    scopus 로고
    • Neurokinin B and specific tachykinin NK3 receptor agonists-induced airway hyperresponsiveness in the guinea-pig
    • DAOUI S, NALINE E, LAGENTE V, EMONDS-ALT X, ADVENIER C: Neurokinin B and specific tachykinin NK3 receptor agonists-induced airway hyperresponsiveness in the guinea-pig. Br. J. Pharmacol. (2000) 130:49-56.
    • (2000) Br. J. Pharmacol. , vol.130 , pp. 49-56
    • Daoui, S.1    Naline, E.2    Lagente, V.3    Emonds-Alt, X.4    Advenier, C.5
  • 110
    • 0031595746 scopus 로고    scopus 로고
    • Involvement of tachykinin NK3 receptors in citric acid-induced cough and bronchial responses in guinea-pigs
    • DAOUI S, COGNON C, NALINE E, EMONDS-ALT X, ADVENIER C: Involvement of tachykinin NK3 receptors in citric acid-induced cough and bronchial responses in guinea-pigs. Am. J. Respir. Crit. Care Med. (1998) 158:42-48.
    • (1998) Am. J. Respir. Crit. Care Med. , vol.158 , pp. 42-48
    • Daoui, S.1    Cognon, C.2    Naline, E.3    Emonds-Alt, X.4    Advenier, C.5
  • 111
    • 18444399636 scopus 로고    scopus 로고
    • Biochemical and pharmacological activities of SSR 146977, a new potent nonpeptide tachykinin NK3 receptor antagonist
    • EMONDS-ALT X, PROIETTO V, STEINBERG R et al.: Biochemical and pharmacological activities of SSR 146977, a new potent nonpeptide tachykinin NK3 receptor antagonist. Can. J. Physiol. Pharmacol. (2002) 80:482-488.
    • (2002) Can. J. Physiol. Pharmacol. , vol.80 , pp. 482-488
    • Emonds-Alt, X.1    Proietto, V.2    Steinberg, R.3
  • 112
    • 18244395370 scopus 로고    scopus 로고
    • Nonpeptide tachykinin receptor antagonists. III. SB 235375, a low central nervous system-penetrant, potent and selective neurokinin-3 receptor antagonist, inhibits citric acid-induced cough and airways hyperreactivity in guinea-pigs
    • HAY DWP, GIARDINA GAM, GRISWOLD DE et al.: Nonpeptide tachykinin receptor antagonists. III. SB 235375, a low central nervous system-penetrant, potent and selective neurokinin-3 receptor antagonist, inhibits citric acid-induced cough and airways hyperreactivity in guinea-pigs. J. Pharmacol. Exp. Ther. (2002) 300:314-323.
    • (2002) J. Pharmacol. Exp. Ther. , vol.300 , pp. 314-323
    • Hay, D.W.P.1    Giardina, G.A.M.2    Griswold, D.E.3
  • 113
    • 18744389431 scopus 로고    scopus 로고
    • 2-adrenoceptor agonist-induced hyperresponsiveness to neurokinin A in guinea-pig isolated trachea
    • 2-adrenoceptor agonist-induced hyperresponsiveness to neurokinin A in guinea-pig isolated trachea. Life Sci. (2002) 72:307-320.
    • (2002) Life Sci. , vol.72 , pp. 307-320
    • Pinto, F.M.1    Saulnier, J.P.2    Faisy, C.3
  • 114
    • 0035930875 scopus 로고    scopus 로고
    • Tachykinin NK3 receptor agonists induced microvascular leakage hypersensitivity in guinea-pig airways
    • DAOUI S, AHNAOU A, NALINE E, EMONDS-ALT X, LAGENTE V, ADVENIER C: Tachykinin NK3 receptor agonists induced microvascular leakage hypersensitivity in guinea-pig airways. Eur. J. Pharmacol. (2001) 433:199-207.
    • (2001) Eur. J. Pharmacol. , vol.433 , pp. 199-207
    • Daoui, S.1    Ahnaou, A.2    Naline, E.3    Emonds-Alt, X.4    Lagente, V.5    Advenier, C.6
  • 115
    • 0035875787 scopus 로고    scopus 로고
    • Inhibition of inflammatory cell recruitment by the tachykinin NK3-receptor antagonist, SR 142801, in a murine model of asthma
    • NENAN S, GERMAIN N, LAGENTEV, EMONDS-ALT X, ADVENIER C, BOICHOT E: Inhibition of inflammatory cell recruitment by the tachykinin NK3-receptor antagonist, SR 142801, in a murine model of asthma. Eur. J. Pharmacol. (2001) 421:201-205.
    • (2001) Eur. J. Pharmacol. , vol.421 , pp. 201-205
    • Nenan, S.1    Germain, N.2    Lagente, V.3    Emonds-Alt, X.4    Advenier, C.5    Boichot, E.6
  • 116
    • 0037272798 scopus 로고    scopus 로고
    • Tachykinin NK3 and NK1 receptor activation elicits secretion from porcine airway submucosal glands
    • PHILLIPS JE, HEY JA, CORBOZ MR: Tachykinin NK3 and NK1 receptor activation elicits secretion from porcine airway submucosal glands. Br. J. Pharmacol. (2003) 138:254-260.
    • (2003) Br. J. Pharmacol. , vol.138 , pp. 254-260
    • Phillips, J.E.1    Hey, J.A.2    Corboz, M.R.3
  • 117
    • 0031240138 scopus 로고    scopus 로고
    • A tachykinin NK3 receptor antagonist, SR 142801 (osanetant), prevents substance P-induced bronchial hyperreactivity in guinea-pigs
    • DAOUI S, CUI YY, LAGENTE V, EMONDS-ALT X, ADVENIER C: A tachykinin NK3 receptor antagonist, SR 142801 (osanetant), prevents substance P-induced bronchial hyperreactivity in guinea-pigs. Pulm. Pharmacol Ther. (1997) 10:261-270.
    • (1997) Pulm. Pharmacol Ther. , vol.10 , pp. 261-270
    • Daoui, S.1    Cui, Y.Y.2    Lagente, V.3    Emonds-Alt, X.4    Advenier, C.5
  • 118
    • 0027255496 scopus 로고
    • Neurokinin A but not neurokinin B and substance P, induces codeine-resistant cough in awake guinea-pigs
    • TAKAHAMA K, FUCHIKAMI J, ISOHAMA Y, KAI H, MIYATA T: Neurokinin A but not neurokinin B and substance P, induces codeine-resistant cough in awake guinea-pigs. Regul. Pept. (1993) 46:236-237.
    • (1993) Regul. Pept. , vol.46 , pp. 236-237
    • Takahama, K.1    Fuchikami, J.2    Isohama, Y.3    Kai, H.4    Miyata, T.5
  • 119
    • 0027139129 scopus 로고
    • Evidence for substance P as an endogenous substance causing cough in guinea-pigs
    • UJIIE Y, SEKIZAWA K, AIKAWA T, SASAKI H: Evidence for substance P as an endogenous substance causing cough in guinea-pigs. Am. Rev. Respir. Dis. (1993) 148:1628-1632.
    • (1993) Am. Rev. Respir. Dis. , vol.148 , pp. 1628-1632
    • Ujiie, Y.1    Sekizawa, K.2    Aikawa, T.3    Sasaki, H.4
  • 120
    • 0034711566 scopus 로고    scopus 로고
    • Role of substance P and tachykinin receptor antagonists in citric acid-induced cough in pigs
    • MOREAUX B, NEMMAR A, VINCKE G et al.: Role of substance P and tachykinin receptor antagonists in citric acid-induced cough in pigs. Eur. J. Pharmacol. (2000) 48:305-312.
    • (2000) Eur. J. Pharmacol. , vol.48 , pp. 305-312
    • Moreaux, B.1    Nemmar, A.2    Vincke, G.3
  • 121
    • 0031771629 scopus 로고    scopus 로고
    • Effects of airway inflammation on cough response in the guinea-pig
    • XIANG A, UCHIDA Y, NOMURA A et al.: Effects of airway inflammation on cough response in the guinea-pig. J. Appl. Physiol. (1998) 85:1847-1854.
    • (1998) J. Appl. Physiol. , vol.85 , pp. 1847-1854
    • Xiang, A.1    Uchida, Y.2    Nomura, A.3
  • 122
    • 0029865997 scopus 로고    scopus 로고
    • Effects of specific tachykinin receptor antagonists on citric acid-induced cough and bronchoconstriction in unanaesdietized guinea-pigs
    • YASUMITSU R, HIRAYAMA Y, IMAI T, MIYAYASU K, HIROI J: Effects of specific tachykinin receptor antagonists on citric acid-induced cough and bronchoconstriction in unanaesdietized guinea-pigs. Eur. J. Pharmacol. (1996) 300:215-219.
    • (1996) Eur. J. Pharmacol. , vol.300 , pp. 215-219
    • Yasumitsu, R.1    Hirayama, Y.2    Imai, T.3    Miyayasu, K.4    Hiroi, J.5
  • 123
    • 0030265432 scopus 로고    scopus 로고
    • Tachykinin receptor antagonists and cough
    • ADVENIER C, EMONDS-ALT X: Tachykinin receptor antagonists and cough. Pulm. Pharmacol. (1996) 9:329-333.
    • (1996) Pulm. Pharmacol. , vol.9 , pp. 329-333
    • Advenier, C.1    Emonds-Alt, X.2
  • 124
    • 0030899572 scopus 로고    scopus 로고
    • Central antitussive activity of the NK1 and NK2 tachykinin receptor antagonists, CP-99,994 and SR 48968, in the guinea-pig and cat
    • BOLSER DC, DEGENNARO FC, O'REILLY S, MCLEOD RL, HEY JA: Central antitussive activity of the NK1 and NK2 tachykinin receptor antagonists, CP-99,994 and SR 48968, in the guinea-pig and cat. Br. J. Pharmacol. (1997) 121:165-170.
    • (1997) Br. J. Pharmacol. , vol.121 , pp. 165-170
    • Bolser, D.C.1    Degennaro, F.C.2    O'Reilly, S.3    Mcleod, R.L.4    Hey, J.A.5
  • 125
    • 0030983591 scopus 로고    scopus 로고
    • Tachykinins in the gut. Expression, release and motor function
    • HOLZER P, HOLZER-PETSCHE U: Tachykinins in the gut. Part I. Expression, release and motor function. Pharmacol. Ther. (1997) 73:173-217.
    • (1997) Pharmacol. Ther. , vol.73 , Issue.PART I , pp. 173-217
    • Holzer, P.1    Holzer-Petsche, U.2
  • 126
    • 0034802383 scopus 로고    scopus 로고
    • Nepadutant pharmacokinetics and dose-effect relationships as tachykinin NK2 receptor antagonist are altered by intestinal inflammation in rodent models
    • LECCI A, CARINI F, TRAMONTANA M et al.: Nepadutant pharmacokinetics and dose-effect relationships as tachykinin NK2 receptor antagonist are altered by intestinal inflammation in rodent models. J. Pharmacol. Exp. Ther. (2001) 299:247-254.
    • (2001) J. Pharmacol. Exp. Ther. , vol.299 , pp. 247-254
    • Lecci, A.1    Carini, F.2    Tramontana, M.3
  • 127
    • 0035118912 scopus 로고    scopus 로고
    • Role of NK2 receptors in gastric barosensitivity and in experimental ileus in rats
    • TOULOUSE M, FIORAMONTI J, MAGGI CA, BUENO L: Role of NK2 receptors in gastric barosensitivity and in experimental ileus in rats. Neurogastroenterol. Mot. (2001) 13:45-53.
    • (2001) Neurogastroenterol. Mot. , vol.13 , pp. 45-53
    • Toulouse, M.1    Fioramonti, J.2    Maggi, C.A.3    Bueno, L.4
  • 128
    • 0033673642 scopus 로고    scopus 로고
    • British society of gastroenterology guidelines for the management of irritable bowel syndrome
    • JONES J, BOORMAN J, CANN P et al.: British society of gastroenterology guidelines for the management of irritable bowel syndrome. Gut (2000) 47(Suppl. 2):S1-S19.
    • (2000) Gut , vol.47 , Issue.SUPPL. 2
    • Jones, J.1    Boorman, J.2    Cann, P.3
  • 129
    • 0035057423 scopus 로고    scopus 로고
    • Irritable bowel syndrome: New agents targeting serotonin receptor subtypes
    • DE PONTI F, TONINI M: Irritable bowel syndrome: new agents targeting serotonin receptor subtypes. Drugs (2001) 61:317-322.
    • (2001) Drugs , vol.61 , pp. 317-322
    • De Ponti, F.1    Tonini, M.2
  • 130
    • 0034036363 scopus 로고    scopus 로고
    • Deficits in visceral pain and hyperalgesia of mice with a disruption of the tachykinin NK1 receptor gene
    • LAIRD JMA, OLIVAR T, ROZA C, DE FELIPE C, HUNT SP, CERVERO F: Deficits in visceral pain and hyperalgesia of mice with a disruption of the tachykinin NK1 receptor gene. Neuroscience (2000) 98:345-352.
    • (2000) Neuroscience , vol.98 , pp. 345-352
    • Laird, J.M.A.1    Olivar, T.2    Roza, C.3    De Felipe, C.4    Hunt, S.P.5    Cervero, F.6
  • 131
    • 0036008323 scopus 로고    scopus 로고
    • Effects of tachykinin NK1 receptor antagonists on the viscerosensory response caused by colorectal distension
    • OKANO S, IKEURA Y, INATOMI N: Effects of tachykinin NK1 receptor antagonists on the viscerosensory response caused by colorectal distension. J. Pharmacol. Exp. Ther. (2002) 300:925-931.
    • (2002) J. Pharmacol. Exp. Ther. , vol.300 , pp. 925-931
    • Okano, S.1    Ikeura, Y.2    Inatomi, N.3
  • 132
    • 0001301235 scopus 로고    scopus 로고
    • A double-blind parallel group pilot study of the effects of CJ-11,974 and placebo on perceptual and emotional responses to rectosigmoid distension in IBS patients
    • LEE OY, MUNAKATA J, NALIBOFF BD, CHANG L, MAYER EA: A double-blind parallel group pilot study of the effects of CJ-11,974 and placebo on perceptual and emotional responses to rectosigmoid distension in IBS patients. Gastroenterology (2000) 118:A846.
    • (2000) Gastroenterology , vol.118
    • Lee, O.Y.1    Munakata, J.2    Naliboff, B.D.3    Chang, L.4    Mayer, E.A.5
  • 133
    • 0032951327 scopus 로고    scopus 로고
    • Randomized Phase II study of the neurokinin 1 receptor antagonist CJ-11,974 in the control of cisplatin-induced emesis
    • HESKETH PJ, GRALLA RJ, WEBB RT et al.: Randomized Phase II study of the neurokinin 1 receptor antagonist CJ-11,974 in the control of cisplatin-induced emesis. J. Clin. Oncol. (1999) 17:338-343.
    • (1999) J. Clin. Oncol. , vol.17 , pp. 338-343
    • Hesketh, P.J.1    Gralla, R.J.2    Webb, R.T.3
  • 136
    • 0035046349 scopus 로고    scopus 로고
    • Response of rat spinal neurons to distension of inflamed colon: Role of tachykinin NK2 receptors
    • LAIRD JMA, OLIVAR T, LOPEZ-GARCIA JA, MAGGI CA, CERVERO F: Response of rat spinal neurons to distension of inflamed colon: role of tachykinin NK2 receptors. Neuropharmacology (2001) 40:696-701.
    • (2001) Neuropharmacology , vol.40 , pp. 696-701
    • Laird, J.M.A.1    Olivar, T.2    Lopez-Garcia, J.A.3    Maggi, C.A.4    Cervero, F.5
  • 137
    • 0037214443 scopus 로고    scopus 로고
    • Effect of nepadutant, a neurokinin 2 tachykinin receptor antagonist, on immediate-early gene expression after trinitrobenzenesulfonic acid-induced colitis in the rat
    • BIRDER LA, KISS S, DE GROAT WC, LECCI A, MAGGI CA: Effect of nepadutant, a neurokinin 2 tachykinin receptor antagonist, on immediate-early gene expression after trinitrobenzenesulfonic acid-induced colitis in the rat. J. Pharmacol. Exp. Ther. (2003) 304:272-276.
    • (2003) J. Pharmacol. Exp. Ther. , vol.304 , pp. 272-276
    • Birder, L.A.1    Kiss, S.2    De Groat, W.C.3    Lecci, A.4    Maggi, C.A.5
  • 138
    • 0035063725 scopus 로고    scopus 로고
    • Chronic low-level administration of diquat increases die nociceptive response to gastric distension in rats: Role of mast cells and tachykinin receptor activation
    • ANTON PM, THEODOROU V, FIORAMONTI J, BUENO L: Chronic low-level administration of diquat increases die nociceptive response to gastric distension in rats: role of mast cells and tachykinin receptor activation. Pain (2001) 92:219-227.
    • (2001) Pain , vol.92 , pp. 219-227
    • Anton, P.M.1    Theodorou, V.2    Fioramonti, J.3    Bueno, L.4
  • 139
    • 0030709227 scopus 로고    scopus 로고
    • Effects of nematode infection on sensitivity to intestinal distension: Role of tachykinin NK2 receptors
    • MCLEAN PG, PICARD C, GARCIA-VILLAR R, MORÉ J, FIORAMONTI J, BUENO L: Effects of nematode infection on sensitivity to intestinal distension: role of tachykinin NK2 receptors. Eur. J. Pharmacol. (1997) 337:279-282.
    • (1997) Eur. J. Pharmacol. , vol.337 , pp. 279-282
    • Mclean, P.G.1    Picard, C.2    Garcia-Villar, R.3    Moré, J.4    Fioramonti, J.5    Bueno, L.6
  • 140
    • 0034840435 scopus 로고    scopus 로고
    • A novel tachykinin NK2 receptor antagonist prevents motility-stimulating effects of neurokinin A in small intestine
    • LORDAL M, NAVALESI G, THEODORSSON E, MAGGI CA, HELLSTROM PM: A novel tachykinin NK2 receptor antagonist prevents motility-stimulating effects of neurokinin A in small intestine. Br. J. Pharmacol. (2001) 134:215-223.
    • (2001) Br. J. Pharmacol. , vol.134 , pp. 215-223
    • Lordal, M.1    Navalesi, G.2    Theodorsson, E.3    Maggi, C.A.4    Hellstrom, P.M.5
  • 141
    • 0035960914 scopus 로고    scopus 로고
    • Neurokinin B potentiates ATP-evoked currents in rat DRG neurons
    • WANG MJ, XIONG SH, LI ZW: Neurokinin B potentiates ATP-evoked currents in rat DRG neurons. Brain Res. (2001) 923:157-162.
    • (2001) Brain Res. , vol.923 , pp. 157-162
    • Wang, M.J.1    Xiong, S.H.2    Li, Z.W.3
  • 142
    • 0028295010 scopus 로고
    • SR48968 selectively prevents faecal excretion following activation of tachykinin NK2 receptors in rats
    • CROCI T, EMONDS-ALT X, MANARA L: SR48968 selectively prevents faecal excretion following activation of tachykinin NK2 receptors in rats. J. Pharm. Pharmacol. (1994) 46:383-385.
    • (1994) J. Pharm. Pharmacol. , vol.46 , pp. 383-385
    • Croci, T.1    Emonds-Alt, X.2    Manara, L.3
  • 143
    • 0032952503 scopus 로고    scopus 로고
    • Role of neurokinin 3 receptors on responses to colorectal distension in the rat: Electrophysiological and behavioral studies
    • JULIA V, SU X, BUENO L, GEBHART GF: Role of neurokinin 3 receptors on responses to colorectal distension in the rat: electrophysiological and behavioral studies. Gastroenterology (1999) 116:1124-1131.
    • (1999) Gastroenterology , vol.116 , pp. 1124-1131
    • Julia, V.1    Su, X.2    Bueno, L.3    Gebhart, G.F.4
  • 144
    • 0029130993 scopus 로고
    • Implication of NK1 and NK2 receptors in rat colonic hypersecretion induced by interleukin 1β: Role of nitric oxide
    • EUTAMENE H, THEODOROU V, FIORAMONTI J, BUENO L: Implication of NK1 and NK2 receptors in rat colonic hypersecretion induced by interleukin 1β: role of nitric oxide. Gastroenterology (1995) 109:483-489.
    • (1995) Gastroenterology , vol.109 , pp. 483-489
    • Eutamene, H.1    Theodorou, V.2    Fioramonti, J.3    Bueno, L.4
  • 145
    • 0030932882 scopus 로고    scopus 로고
    • Rectal distension-induced colonic net water secretion in rats involves tachykinins, capsaicin sensory, and vagus nerves
    • EUTAMENE H, THEODOROU V, FIORAMONTI J, BUENO L: Rectal distension-induced colonic net water secretion in rats involves tachykinins, capsaicin sensory, and vagus nerves. Gastroenterology (1997) 112:1595-1602.
    • (1997) Gastroenterology , vol.112 , pp. 1595-1602
    • Eutamene, H.1    Theodorou, V.2    Fioramonti, J.3    Bueno, L.4
  • 147
    • 0034865533 scopus 로고    scopus 로고
    • Human colonic anti-secretory activity of the potent NK1 antagonist SR140333: Assessment of potential anti-diarrhoeal activity in food allergy and inflammatory bowel disease
    • MORIARTY D, GOLDHILL J, SELVE N, O'DONOGHUE DP, BAIRD AW: Human colonic anti-secretory activity of the potent NK1 antagonist SR140333: assessment of potential anti-diarrhoeal activity in food allergy and inflammatory bowel disease. Br. J. Pharmacol. (2001) 133:1346-1354.
    • (2001) Br. J. Pharmacol. , vol.133 , pp. 1346-1354
    • Moriarty, D.1    Goldhill, J.2    Selve, N.3    O'Donoghue, D.P.4    Baird, A.W.5
  • 148
    • 0037291712 scopus 로고    scopus 로고
    • Dual and selective antagonism of neurokinin NK1 and NK2 receptor-mediated responses in human colon mucosa
    • TOUGH IR, LEWIS CA, FOZARD J, COX HM: Dual and selective antagonism of neurokinin NK1 and NK2 receptor-mediated responses in human colon mucosa. Naunyn Schmiedebergs Arch. Pharmacol. (2003) 367:104-108.
    • (2003) Naunyn Schmiedebergs Arch. Pharmacol. , vol.367 , pp. 104-108
    • Tough, I.R.1    Lewis, C.A.2    Fozard, J.3    Cox, H.M.4
  • 149
    • 0033774008 scopus 로고    scopus 로고
    • Neurokinin 1 and 2 receptors mediate cholera toxin secretion in rat jejunum
    • TURVILL JL, CONNOR P, FARTHING JG: Neurokinin 1 and 2 receptors mediate cholera toxin secretion in rat jejunum. Gastroenterology (2000) 119:1037-1044.
    • (2000) Gastroenterology , vol.119 , pp. 1037-1044
    • Turvill, J.L.1    Connor, P.2    Farthing, J.G.3
  • 150
    • 0035876679 scopus 로고    scopus 로고
    • Differential alterations in tachykinin NK2 receptors in isolated colonic circular smooth muscle in inflammatory bowel disease and idiopathic chronic constipation
    • MENZIES JRW, MCKEE R, CORBETT AD: Differential alterations in tachykinin NK2 receptors in isolated colonic circular smooth muscle in inflammatory bowel disease and idiopathic chronic constipation. Regul. Pept. (2001) 99:151-156.
    • (2001) Regul. Pept. , vol.99 , pp. 151-156
    • Menzies, J.R.W.1    Mckee, R.2    Corbett, A.D.3
  • 151
    • 0036070721 scopus 로고    scopus 로고
    • Roles of substance P receptors in human colon circular muscle: Alterations in diverticular disease
    • LIU L, SHANG F, MARKUS I, BURCHER E: Roles of substance P receptors in human colon circular muscle: alterations in diverticular disease. J. Pharmacol. Exp. Ther. (2002) 302:627-635.
    • (2002) J. Pharmacol. Exp. Ther. , vol.302 , pp. 627-635
    • Liu, L.1    Shang, F.2    Markus, I.3    Burcher, E.4
  • 152
    • 0036083475 scopus 로고    scopus 로고
    • Abnormal motility in patients with ulcerative colitis: The role of inflammatory cytokines
    • VREES MD, PRICOLO VE, POTENTI FM, CAO W: Abnormal motility in patients with ulcerative colitis: the role of inflammatory cytokines. Arch. Surg. (2002) 137:439-445.
    • (2002) Arch. Surg. , vol.137 , pp. 439-445
    • Vrees, M.D.1    Pricolo, V.E.2    Potenti, F.M.3    Cao, W.4
  • 153
    • 0034037393 scopus 로고    scopus 로고
    • Substance P mediates inflammatory oedema in acute pancreatitis via activation of the neurokinin-1 receptor in rats and mice
    • GRADY EF, YOSHIMI SK, MAA J et al.: Substance P mediates inflammatory oedema in acute pancreatitis via activation of the neurokinin-1 receptor in rats and mice. Br. J. Pharmacol. (2000) 130:505-512.
    • (2000) Br. J. Pharmacol. , vol.130 , pp. 505-512
    • Grady, E.F.1    Yoshimi, S.K.2    Maa, J.3
  • 154
    • 0033624356 scopus 로고    scopus 로고
    • Substance P is a determinant of lethality in diet-induced hemorrhagic pancreatitis in mice
    • MAA J, GRADY EF, YOSHIMI SK et al.: Substance P is a determinant of lethality in diet-induced hemorrhagic pancreatitis in mice. Surgery (2000) 128:232-239.
    • (2000) Surgery , vol.128 , pp. 232-239
    • Maa, J.1    Grady, E.F.2    Yoshimi, S.K.3
  • 155
    • 0037379926 scopus 로고    scopus 로고
    • Neurokinin-1 receptor antagonists CP96345 and L733060 protect mice from cytokine-mediated liver injury
    • BANG R, SASS G, KIEMER AK et al.: Neurokinin-1 receptor antagonists CP96345 and L733060 protect mice from cytokine-mediated liver injury. J. Pharmacol. Exp. Ther. (2003) 305:31-39.
    • (2003) J. Pharmacol. Exp. Ther. , vol.305 , pp. 31-39
    • Bang, R.1    Sass, G.2    Kiemer, A.K.3
  • 156
    • 0034185210 scopus 로고    scopus 로고
    • Intravesical treatment of overactive bladder
    • FOWLER CJ: Intravesical treatment of overactive bladder. Urology (2000) 55(Suppl. 5A):S60-S64.
    • (2000) Urology , vol.55 , Issue.SUPPL. 5A
    • Fowler, C.J.1
  • 157
    • 0033950419 scopus 로고    scopus 로고
    • The effect of intravesical capsaicin on suburothelial innervation in patients with detrusor hyperreflexia
    • DASGUPTA P, CHANDIRAMANI VA, BECKETT A, SCARAVILLI F, FOWLER CJ: The effect of intravesical capsaicin on suburothelial innervation in patients with detrusor hyperreflexia. Br. J. Urol. (2000) 85:238-245.
    • (2000) Br. J. Urol. , vol.85 , pp. 238-245
    • Dasgupta, P.1    Chandiramani, V.A.2    Beckett, A.3    Scaravilli, F.4    Fowler, C.J.5
  • 158
    • 0020954472 scopus 로고
    • Sensory substance P innervation of the urinary bladder, possible site of action of capsaicin in causing urinary retention in rats
    • SHARKEY KA, WILLIAMS RG, SHULTZBERG M, DOCKRAY GJ: Sensory substance P innervation of the urinary bladder, possible site of action of capsaicin in causing urinary retention in rats. Neuroscience (1983) 10:861-868.
    • (1983) Neuroscience , vol.10 , pp. 861-868
    • Sharkey, K.A.1    Williams, R.G.2    Shultzberg, M.3    Dockray, G.J.4
  • 159
    • 0027725287 scopus 로고
    • Substance P-containing axon terminals in the mucosa of the human urinary bladder: Pre-embedding immunohistochemistry using cryostat sections for electron microscopy
    • WAKABAYASHI Y, TOMOYOSHI T, FUJIMIYA M, ARAI R, MAEDA T: Substance P-containing axon terminals in the mucosa of the human urinary bladder: pre-embedding immunohistochemistry using cryostat sections for electron microscopy. Histochemistry (1993) 100:401-407.
    • (1993) Histochemistry , vol.100 , pp. 401-407
    • Wakabayashi, Y.1    Tomoyoshi, T.2    Fujimiya, M.3    Arai, R.4    Maeda, T.5
  • 160
    • 0034727918 scopus 로고    scopus 로고
    • Peptide immunoreactivity and ultrastructure of rat urinary bladder nerve fibers after topical desensitization by capsaicin and resiniferatoxin
    • AVELINO A, CRUZ F: Peptide immunoreactivity and ultrastructure of rat urinary bladder nerve fibers after topical desensitization by capsaicin and resiniferatoxin. Auton. Neurosci. (2000) 86:37-46.
    • (2000) Auton. Neurosci. , vol.86 , pp. 37-46
    • Avelino, A.1    Cruz, F.2
  • 161
    • 0023261881 scopus 로고
    • The contribution of capsaicin-sensitive innervation to activation of the spinal vesico-vesical reflex in rats: Relationship between substance P levels in the urinary bladder and the sensory-efferent function of capsaicin-sensitive sensory neurons
    • MAGGI CA, SANTICIOLI P, GEPPETTI P et al.: The contribution of capsaicin-sensitive innervation to activation of the spinal vesico-vesical reflex in rats: relationship between substance P levels in the urinary bladder and the sensory-efferent function of capsaicin-sensitive sensory neurons. Brain Res. (1987) 415:1-13.
    • (1987) Brain Res. , vol.415 , pp. 1-13
    • Maggi, C.A.1    Santicioli, P.2    Geppetti, P.3
  • 162
    • 0028954338 scopus 로고
    • Effect of capsaicin on micturition and associated reflexes in chronic spinal rats
    • CHENG CL, MA CP, DE GROAT WC: Effect of capsaicin on micturition and associated reflexes in chronic spinal rats. Brain Res. (1995) 678:40-48.
    • (1995) Brain Res. , vol.678 , pp. 40-48
    • Cheng, C.L.1    Ma, C.P.2    De Groat, W.C.3
  • 163
    • 27844466058 scopus 로고    scopus 로고
    • Hyperreflexia of the urinary bladder: Possible role of the efferent function of the capsaicin sensitive primary afferents
    • SHAKER HS, TU LM, KALFOPOULOS M, HASSOUNA M, DION S, ELHILALI M: Hyperreflexia of the urinary bladder: possible role of the efferent function of the capsaicin sensitive primary afferents. J. Urol. (1998) 160:2232-2239.
    • (1998) J. Urol. , vol.160 , pp. 2232-2239
    • Shaker, H.S.1    Tu, L.M.2    Kalfopoulos, M.3    Hassouna, M.4    Dion, S.5    Elhilali, M.6
  • 164
    • 0035043352 scopus 로고    scopus 로고
    • Evidence of a peripheral role of neurokinins in detrusor hyperreflexia: A further study of selective tachykinin antagonists in
    • ABDEL-GAWAD M, DION SB, ELHILALI MM: Evidence of a peripheral role of neurokinins in detrusor hyperreflexia: a further study of selective tachykinin antagonists in chronic spinal injured rats. J. Urol. (2001) 165:1739-1744.
    • (2001) J. Urol. , vol.165 , pp. 1739-1744
    • Abdel-Gawad, M.1    Dion, S.B.2    Elhilali, M.M.3
  • 165
    • 0038176796 scopus 로고    scopus 로고
    • Effects of M274773, a new tachykinin NK2 receptor antagonist, on bladder function of spinalized rats
    • P-7.4.25
    • ABDEL-KARIM A, BIALECKI R, ELHILALI MM: Effects of M274773, a new tachykinin NK2 receptor antagonist, on bladder function of spinalized rats. Br. J. Urol. Int. (2002) 90(Suppl. 2):P-7.4.25.
    • (2002) Br. J. Urol. Int. , vol.90 , Issue.SUPPL. 2
    • Abdel-Karim, A.1    Bialecki, R.2    Elhilali, M.M.3
  • 166
    • 0035885406 scopus 로고    scopus 로고
    • Tachykinins as modulators of the micturition reflex in the central and peripheral nervous system
    • LECCI A, MAGGI CA: Tachykinins as modulators of the micturition reflex in the central and peripheral nervous system. Regul. Pept. (2001) 101:1-18.
    • (2001) Regul. Pept. , vol.101 , pp. 1-18
    • Lecci, A.1    Maggi, C.A.2
  • 167
    • 0001874776 scopus 로고
    • Autoradiographic characterization of prejunctional neurokinin receptors in the rat bladder
    • CARSTAIRS JR, NIMMO AJ, MORRISON JFB: Autoradiographic characterization of prejunctional neurokinin receptors in the rat bladder. Neuropeptides (1992) 22:13-14.
    • (1992) Neuropeptides , vol.22 , pp. 13-14
    • Carstairs, J.R.1    Nimmo, A.J.2    Morrison, J.F.B.3
  • 168
    • 0026098432 scopus 로고
    • Facilitation of reflex micturition by intravesical administration of [βAla8]-neurokinin A (4-10), a selective NK2 tachykinin receptor agonist
    • MAGGI CA, GIULIANI S, SANTICIOLI P, ABELLI L, GIACHETTI A: Facilitation of reflex micturition by intravesical administration of [βAla8]-neurokinin A (4-10), a selective NK2 tachykinin receptor agonist. J. Urol. (1991) 145:184-187.
    • (1991) J. Urol. , vol.145 , pp. 184-187
    • Maggi, C.A.1    Giuliani, S.2    Santicioli, P.3    Abelli, L.4    Giachetti, A.5
  • 169
    • 0029006740 scopus 로고
    • Tachykinin effects on bladder activity in conscious normal rats
    • ISHIZUKA O, MATTIASSON A, ANDERSSON KE: Tachykinin effects on bladder activity in conscious normal rats. J. Urol. (1995) 154:257-261.
    • (1995) J. Urol. , vol.154 , pp. 257-261
    • Ishizuka, O.1    Mattiasson, A.2    Andersson, K.E.3
  • 170
    • 0028988940 scopus 로고
    • 2-induced bladder hyperactivity in normal, conscious rats: Involvement of tachykinins?
    • 2-induced bladder hyperactivity in normal, conscious rats: involvement of tachykinins? J. Urol. (1995) 153:2034-2038.
    • (1995) J. Urol. , vol.153 , pp. 2034-2038
    • Ishizuka, O.1    Mattiasson, A.2    Andersson, K.E.3
  • 171
    • 0032219220 scopus 로고    scopus 로고
    • Effect of tachykinin NK2 receptor blockade on detrusor hyperreflexia induced by bacterial toxin in rats
    • LECCI A, TRAMONTANA M, GIULIANI S, CRISCUOLI M, MAGGI CA: Effect of tachykinin NK2 receptor blockade on detrusor hyperreflexia induced by bacterial toxin in rats. J. Urol. (1998) 160:206-209.
    • (1998) J. Urol. , vol.160 , pp. 206-209
    • Lecci, A.1    Tramontana, M.2    Giuliani, S.3    Criscuoli, M.4    Maggi, C.A.5
  • 172
    • 0034018296 scopus 로고    scopus 로고
    • Pharmacological evaluation of the role of cyclooxygenase isoenzymes on the micturition reflex following experimental cystitis
    • LECCI A, BIRDER LA, MEINI S et al.: Pharmacological evaluation of the role of cyclooxygenase isoenzymes on the micturition reflex following experimental cystitis. Br. J. Pharmacol. (2000) 130:331-338.
    • (2000) Br. J. Pharmacol. , vol.130 , pp. 331-338
    • Lecci, A.1    Birder, L.A.2    Meini, S.3
  • 173
    • 0028287325 scopus 로고
    • Capsaicin-induced bladder hyperreactivity in normal conscious rats
    • ISHIZUKA O, IGAWA Y, MATTIASSON A, ANDERSSON KE: Capsaicin-induced bladder hyperreactivity in normal conscious rats. J. Urol. (1994) 152:525-530.
    • (1994) J. Urol. , vol.152 , pp. 525-530
    • Ishizuka, O.1    Igawa, Y.2    Mattiasson, A.3    Andersson, K.E.4
  • 174
    • 0030859261 scopus 로고    scopus 로고
    • MEN11420, a peptide tachykinin NK2 receptor antagonist, reduces motor responses induced by the intravesical administration of capsaicin in vivo
    • LECCI A, GIULIANI S, TRAMONTANA M, CRISCUOLI M, MAGGI CA: MEN11420, a peptide tachykinin NK2 receptor antagonist, reduces motor responses induced by the intravesical administration of capsaicin in vivo. Naunyn Schmiedebergs Arch. Pharmacol. (1997) 356:182-188.
    • (1997) Naunyn Schmiedebergs Arch. Pharmacol. , vol.356 , pp. 182-188
    • Lecci, A.1    Giuliani, S.2    Tramontana, M.3    Criscuoli, M.4    Maggi, C.A.5
  • 175
    • 0035855403 scopus 로고    scopus 로고
    • Urodynamic effects induced by intravesical capsaicin in rats and hamsters
    • LECCI A, CARINI F, TRAMONTANA M et al.: Urodynamic effects induced by intravesical capsaicin in rats and hamsters. Auton. Neurosci. (2001) 91:37-46.
    • (2001) Auton. Neurosci. , vol.91 , pp. 37-46
    • Lecci, A.1    Carini, F.2    Tramontana, M.3
  • 176
    • 0025909014 scopus 로고
    • In vivo evidence for tachykininergic transmission using a new NK2 receptor selective antagonist
    • MAGGI CA, GIULIANI S, BALLATI L et al.: In vivo evidence for tachykininergic transmission using a new NK2 receptor selective antagonist. J. Pharmacol. Exp. Ther. (1991b) 257:1172-1178.
    • (1991) J. Pharmacol. Exp. Ther. , vol.257 , pp. 1172-1178
    • Maggi, C.A.1    Giuliani, S.2    Ballati, L.3
  • 177
    • 0000455239 scopus 로고
    • Effect of selective antagonists at tachykinin NK1 and NK2 receptors on xylene-induced cystitis in rats
    • PIETRA C, BETTELLINI R, HAGAN RM, WARD P, MCELROY A, TRIST DG: Effect of selective antagonists at tachykinin NK1 and NK2 receptors on xylene-induced cystitis in rats. Neuropeptides (1992) 22:52.
    • (1992) Neuropeptides , vol.22 , pp. 52
    • Pietra, C.1    Bettellini, R.2    Hagan, R.M.3    Ward, P.4    Mcelroy, A.5    Trist, D.G.6
  • 178
    • 0036718048 scopus 로고    scopus 로고
    • Intravesical adenosine triphosphate stimulates the micturition reflex in awake, freely moving rats
    • PANDITA RK, ANDERSSON KE: Intravesical adenosine triphosphate stimulates the micturition reflex in awake, freely moving rats. J. Urol. (2002) 168:1230-1234.
    • (2002) J. Urol. , vol.168 , pp. 1230-1234
    • Pandita, R.K.1    Andersson, K.E.2
  • 179
    • 0029112012 scopus 로고
    • Activation of micturition reflex by NK2 receptor stimulation in the anaesthetized guinea-pig
    • BUSHFIELD M, METCALFE M, NAYLOR AM: Activation of micturition reflex by NK2 receptor stimulation in the anaesthetized guinea-pig. Br. J. Pharmacol. (1995) 115:875-882.
    • (1995) Br. J. Pharmacol. , vol.115 , pp. 875-882
    • Bushfield, M.1    Metcalfe, M.2    Naylor, A.M.3
  • 180
    • 0026557932 scopus 로고
    • Reactive changes in neurokinin receptor density following selective denervations and outlet obstruction of rat bladder
    • NIMMO AJ, ANDERSSON PO, MORRISON JFB: Reactive changes in neurokinin receptor density following selective denervations and outlet obstruction of rat bladder. J. Physiol. (1992) 446:524.
    • (1992) J. Physiol. , vol.446 , pp. 524
    • Nimmo, A.J.1    Andersson, P.O.2    Morrison, J.F.B.3
  • 181
    • 0001992656 scopus 로고    scopus 로고
    • Changes in mechanosensitivity and sensitization of urinary bladder afferents in the anesthetized rat following the administration of the selective NK2 antagonist SR48968
    • KIBBLE A, MORRISON JFB: Changes in mechanosensitivity and sensitization of urinary bladder afferents in the anesthetized rat following the administration of the selective NK2 antagonist SR48968. J. Physiol. (1996) 497.P, 18P.
    • (1996) J. Physiol. , vol.497 P
    • Kibble, A.1    Morrison, J.F.B.2
  • 182
    • 0032619275 scopus 로고    scopus 로고
    • The activation of bladder wall afferent nerves
    • MORRISON JFB: The activation of bladder wall afferent nerves. Exp. Physiol. (1999) 84:131-136.
    • (1999) Exp. Physiol. , vol.84 , pp. 131-136
    • Morrison, J.F.B.1
  • 183
    • 3142617911 scopus 로고
    • Tension receptors in the stomach and the urinary bladder
    • IGGO A: Tension receptors in the stomach and the urinary bladder. J. Physiol. (1955) 128:593-607.
    • (1955) J. Physiol. , vol.128 , pp. 593-607
    • Iggo, A.1
  • 184
    • 0034110474 scopus 로고    scopus 로고
    • Role of prostanoids in the contraction induced by a tachykinin NK2 receptor agonist in the hamster urinary bladder
    • TRAMONTANA M, CATALIOTO RM, LECCI A, MAGGI CA: Role of prostanoids in the contraction induced by a tachykinin NK2 receptor agonist in the hamster urinary bladder. Naunyn Schmiedebergs Arch. Pharmacol. (2000) 361:452-459.
    • (2000) Naunyn Schmiedebergs Arch. Pharmacol. , vol.361 , pp. 452-459
    • Tramontana, M.1    Catalioto, R.M.2    Lecci, A.3    Maggi, C.A.4
  • 185
    • 0026599506 scopus 로고
    • Prostanoids as local modulators of reflex micturition
    • MAGGI CA: Prostanoids as local modulators of reflex micturition. Pharmacol. Res. (1992) 25:13-20.
    • (1992) Pharmacol. Res. , vol.25 , pp. 13-20
    • Maggi, C.A.1
  • 186
    • 0031468013 scopus 로고    scopus 로고
    • ATP is released from rabbit urinary bladder epithelial cells by hydrostatic pressure changes - A possible sensory mechanism?
    • FERGUSON DR, KENNEDY I, BURTON TJ: ATP is released from rabbit urinary bladder epithelial cells by hydrostatic pressure changes - a possible sensory mechanism? J. Physiol. (1997) 505(2):503-511.
    • (1997) J. Physiol. , vol.505 , Issue.2 , pp. 503-511
    • Ferguson, D.R.1    Kennedy, I.2    Burton, T.J.3
  • 187
    • 0035413364 scopus 로고    scopus 로고
    • P2X3 knock-out mice reveal a major sensory role for urothelial released ATP
    • VLASKOVSKA M, KASALOV L, RONG W et al.: P2X3 knock-out mice reveal a major sensory role for urothelial released ATP. J. Neurosci. (2001) 21:5670-5677.
    • (2001) J. Neurosci. , vol.21 , pp. 5670-5677
    • Vlaskovska, M.1    Kasalov, L.2    Rong, W.3
  • 188
    • 0033897376 scopus 로고    scopus 로고
    • Intravesical resiniferatoxin for the treatment of hypersensitive disorders: A randomized placebo-controlled study
    • LAZZERI M, BENEFORTI P, SPINELLI M, ZANOLLO A., BARBAGLI G, TURINI D: Intravesical resiniferatoxin for the treatment of hypersensitive disorders: a randomized placebo-controlled study. J. Urol. (2000) 164:676-679.
    • (2000) J. Urol. , vol.164 , pp. 676-679
    • Lazzeri, M.1    Beneforti, P.2    Spinelli, M.3    Zanollo, A.4    Barbagli, G.5    Turini, D.6
  • 189
    • 0036077240 scopus 로고    scopus 로고
    • The effect of intravesical resiniferatoxin in patients with idiopathic detrusor instability suggests that involuntary detrusor contractions are triggered by C-fiber input
    • SILVA C, RIBEIRO MJ, CRUZ F: The effect of intravesical resiniferatoxin in patients with idiopathic detrusor instability suggests that involuntary detrusor contractions are triggered by C-fiber input. J. Urol. (2002) 168:575-579.
    • (2002) J. Urol. , vol.168 , pp. 575-579
    • Silva, C.1    Ribeiro, M.J.2    Cruz, F.3
  • 190
    • 0033918053 scopus 로고    scopus 로고
    • Role of neurokinin receptors in the behavioral effect of intravesical antigen infusion in guinea-pig bladder
    • RUGGIERI MR, FILER-MAERTEN S, HIEBLE JP, HAY DW: Role of neurokinin receptors in the behavioral effect of intravesical antigen infusion in guinea-pig bladder. J. Urol. (2000) 164:197-202.
    • (2000) J. Urol. , vol.164 , pp. 197-202
    • Ruggieri, M.R.1    Filer-Maerten, S.2    Hieble, J.P.3    Hay, D.W.4
  • 191
    • 0035798291 scopus 로고    scopus 로고
    • Impaired response to chemical irritation of the urinary tract in mice with disruption of the preprotachykinin gene
    • KISS S,YOSHIYAMA M, CAO YC et al.: Impaired response to chemical irritation of the urinary tract in mice with disruption of the preprotachykinin gene. Neurosci. Lett. (2001) 313:57-60.
    • (2001) Neurosci. Lett. , vol.313 , pp. 57-60
    • Kiss, S.1    Yoshiyama, M.2    Cao, Y.C.3
  • 192
    • 0028839021 scopus 로고
    • Effects of tachykinins on the secretory activity of rat Sertoli cells in vitro
    • RAO JN, DEBELJUK L, BARTKE A: Effects of tachykinins on the secretory activity of rat Sertoli cells in vitro. Endocrinology (1995) 136:1315-1318.
    • (1995) Endocrinology , vol.136 , pp. 1315-1318
    • Rao, J.N.1    Debeljuk, L.2    Bartke, A.3
  • 193
    • 0035383210 scopus 로고    scopus 로고
    • Urinary substance P concentration correlates with urinary frequency and urgency in interstitial cystitis patients treated with intravesical dimethyl sulfoxide and not intravesical anesthetic cocktail
    • KUSHNER L, CHIU PY, BRETTSCHNEIDER N et al.: Urinary substance P concentration correlates with urinary frequency and urgency in interstitial cystitis patients treated with intravesical dimethyl sulfoxide and not intravesical anesthetic cocktail. Urology (2001) 57(Suppl. A):S129.
    • (2001) Urology , vol.57 , Issue.SUPPL. A
    • Kushner, L.1    Chiu, P.Y.2    Brettschneider, N.3
  • 194
    • 0029048454 scopus 로고
    • Increased number of substance P positive nerve fibres in interstitial cystitis
    • PANG X, MARCHAND J, SANT GR, KREAM RM, THEOHARIDES TC: Increased number of substance P positive nerve fibres in interstitial cystitis. Br. J. Urol. (1995) 75:744-750.
    • (1995) Br. J. Urol. , vol.75 , pp. 744-750
    • Pang, X.1    Marchand, J.2    Sant, G.R.3    Kream, R.M.4    Theoharides, T.C.5
  • 195
    • 0030872289 scopus 로고    scopus 로고
    • Distribution and colocalization of calcitonin gene-related peptide, tachykinins, and vasoactive intestinal peptide in normal and idiopathic unstable human urinary bladder
    • SMET PJ, MOORE KH, JONAVICIUS J: Distribution and colocalization of calcitonin gene-related peptide, tachykinins, and vasoactive intestinal peptide in normal and idiopathic unstable human urinary bladder. Lab. Invest. (1997) 77:37-49.
    • (1997) Lab. Invest. , vol.77 , pp. 37-49
    • Smet, P.J.1    Moore, K.H.2    Jonavicius, J.3
  • 196
    • 0034022714 scopus 로고    scopus 로고
    • Increased tyrosine hydroxylase immunoreactivity in bladder tissue from patients with classic and nonulcer interstitial cystitis
    • PEEKER R, ALDENBERGF, DAHLSTROM A. JOHANSSON SL, LI JY, FALL M: Increased tyrosine hydroxylase immunoreactivity in bladder tissue from patients with classic and nonulcer interstitial cystitis. J. Urol. (2000) 163:1112-1115.
    • (2000) J. Urol. , vol.163 , pp. 1112-1115
    • Peeker, R.1    Aldenberg, F.2    Dahlstrom, A.3    Johansson, S.L.4    Li, J.Y.5    Fall, M.6
  • 197
    • 0035148374 scopus 로고    scopus 로고
    • Urinary levels of substance P and its metabolites are not increased in interstitial cystitis
    • CAMPBELL DJ, TENIS N, ROSAMILIA A, CLEMENTS JA, DWYER PL: Urinary levels of substance P and its metabolites are not increased in interstitial cystitis. Br. J. Urol. (2001) 87:35-38.
    • (2001) Br. J. Urol. , vol.87 , pp. 35-38
    • Campbell, D.J.1    Tenis, N.2    Rosamilia, A.3    Clements, J.A.4    Dwyer, P.L.5
  • 198
    • 0027452372 scopus 로고
    • Characterization of the tachykinin neurokinin-2 receptor in the human urinary bladder by means of selective receptor antagonists and peptidase inhibitors
    • GIULIANI S, PATACCHINI R, BARBANTI G et al.: Characterization of the tachykinin neurokinin-2 receptor in the human urinary bladder by means of selective receptor antagonists and peptidase inhibitors. J. Pharmacol. Exp. Ther. (1993) 267:590-595.
    • (1993) J. Pharmacol. Exp. Ther. , vol.267 , pp. 590-595
    • Giuliani, S.1    Patacchini, R.2    Barbanti, G.3
  • 199
    • 0028988096 scopus 로고
    • Characterization of tachykinin NK2 receptors in human urinary bladder
    • ZENG XP, MOORE KH, BURCHER E: Characterization of tachykinin NK2 receptors in human urinary bladder. J. Urol. (1995) 153:1688-1692.
    • (1995) J. Urol. , vol.153 , pp. 1688-1692
    • Zeng, X.P.1    Moore, K.H.2    Burcher, E.3
  • 200
    • 0033869977 scopus 로고    scopus 로고
    • Neurokinin-1 (NK-1) receptor is required in antigen-induced cystitis
    • SABAN R, SABAN MR, NGUYEN NB et al.: Neurokinin-1 (NK-1) receptor is required in antigen-induced cystitis. Am. J. Pathol. (2000) 156:775-780.
    • (2000) Am. J. Pathol. , vol.156 , pp. 775-780
    • Saban, R.1    Saban, M.R.2    Nguyen, N.B.3
  • 201
    • 0030424077 scopus 로고    scopus 로고
    • Pharmacological characterization of tachykinin NK2 receptors on isolated human urinary bladder, prostatic urethra and prostate
    • PALEA S, CORSI M, ARTIBANI W, OSTARDO E, PIETRA C: Pharmacological characterization of tachykinin NK2 receptors on isolated human urinary bladder, prostatic urethra and prostate. J. Pharmacol. Exp. Ther. (1996) 277:700-705.
    • (1996) J. Pharmacol. Exp. Ther. , vol.277 , pp. 700-705
    • Palea, S.1    Corsi, M.2    Artibani, W.3    Ostardo, E.4    Pietra, C.5
  • 203
    • 0028230538 scopus 로고
    • Characterization of the capsaicin-sensitive component of cyclophosphamide-induced inflammation in the rat urinary bladder
    • AHLUWALIA A, MAGGI CA, SANTICIOLI P, LECCI A, GIULIANI S: Characterization of the capsaicin-sensitive component of cyclophosphamide-induced inflammation in the rat urinary bladder. Br. J. Pharmacol. (1994) 111:1017-1022.
    • (1994) Br. J. Pharmacol. , vol.111 , pp. 1017-1022
    • Ahluwalia, A.1    Maggi, C.A.2    Santicioli, P.3    Lecci, A.4    Giuliani, S.5
  • 204
    • 0030610541 scopus 로고    scopus 로고
    • The NK1 antagonist GR203040 inhibits cyclophosphamide-induced damage in the rat and ferret bladder
    • ALFIERI AB, GARDNER C: The NK1 antagonist GR203040 inhibits cyclophosphamide-induced damage in the rat and ferret bladder. Gen. Pharmacol. (1997) 29:245-250.
    • (1997) Gen. Pharmacol. , vol.29 , pp. 245-250
    • Alfieri, A.B.1    Gardner, C.2
  • 205
    • 0033775712 scopus 로고    scopus 로고
    • Nitric oxide and NK1-tachykinin receptors in cyclophosphamide-induced cystitis, in rats
    • ALFIERI AB, CUBEDDU LX: Nitric oxide and NK1-tachykinin receptors in cyclophosphamide-induced cystitis, in rats. J. Pharmacol. Exp. Ther. (2000) 295:824-829.
    • (2000) J. Pharmacol. Exp. Ther. , vol.295 , pp. 824-829
    • Alfieri, A.B.1    Cubeddu, L.X.2
  • 207
    • 0031595090 scopus 로고    scopus 로고
    • Impaired IL-1β-induced neutrophil accumulation in tachykinin NK1 receptor knockout mice
    • AHLUWALIA A, DE FELIPE C, O'BRIEN J, HUNT SP, PERRETTI M: Impaired IL-1β-induced neutrophil accumulation in tachykinin NK1 receptor knockout mice. Br. J. Pharmacol. (1998) 124:1013-1015.
    • (1998) Br. J. Pharmacol. , vol.124 , pp. 1013-1015
    • Ahluwalia, A.1    De Felipe, C.2    O'Brien, J.3    Hunt, S.P.4    Perretti, M.5
  • 208
    • 0033624773 scopus 로고    scopus 로고
    • Role of NK1 receptors on cisplatin-induced nephrotoxicity in the rat
    • ALFIERI AB, CUBEDDU LX: Role of NK1 receptors on cisplatin-induced nephrotoxicity in the rat. Naunyn Schmiedebergs Arch. Pharmacol. (2001) 361:334-338.
    • (2001) Naunyn Schmiedebergs Arch. Pharmacol. , vol.361 , pp. 334-338
    • Alfieri, A.B.1    Cubeddu, L.X.2
  • 209
    • 0034660105 scopus 로고    scopus 로고
    • Excessive placental secretion of neurokinin B during the third trimester causes pre-eclampsia
    • PAGE NM, WOODS RJ, GARDINER SM et al.: Excessive placental secretion of neurokinin B during the third trimester causes pre-eclampsia. Nature (2000) 405:797-800.
    • (2000) Nature , vol.405 , pp. 797-800
    • Page, N.M.1    Woods, R.J.2    Gardiner, S.M.3
  • 210
    • 0030036623 scopus 로고    scopus 로고
    • Study of SR142801, a new potent non-peptide NK3 receptor antagonist on cardiovascular responses in conscious guinea-pigs
    • ROCCON A, MARCHIONNI D, NISATO D: Study of SR142801, a new potent non-peptide NK3 receptor antagonist on cardiovascular responses in conscious guinea-pigs. Br. J. Pharmacol. (1996) 118:1095-1102.
    • (1996) Br. J. Pharmacol. , vol.118 , pp. 1095-1102
    • Roccon, A.1    Marchionni, D.2    Nisato, D.3
  • 211
    • 0037106314 scopus 로고    scopus 로고
    • Neurokinin B induces oedema formation in the mouse lung via tachykinin receptor-independent mechanisms
    • GRANT AD, AKHTAR R, GERARD NP, BRAIN SD: Neurokinin B induces oedema formation in the mouse lung via tachykinin receptor-independent mechanisms. J. Physiol. (2002) 543:1007-1014.
    • (2002) J. Physiol. , vol.543 , pp. 1007-1014
    • Grant, A.D.1    Akhtar, R.2    Gerard, N.P.3    Brain, S.D.4
  • 212
    • 0035793947 scopus 로고    scopus 로고
    • Immunologically-induced histamine release from rat peritoneal mast cells is enhanced by low levels of substance P
    • LAU AH, CHOW SS, NG YS: Immunologically-induced histamine release from rat peritoneal mast cells is enhanced by low levels of substance P. Eur. J. Pharmacol. (2001) 414:295-303.
    • (2001) Eur. J. Pharmacol. , vol.414 , pp. 295-303
    • Lau, A.H.1    Chow, S.S.2    Ng, Y.S.3
  • 214
    • 0036295872 scopus 로고    scopus 로고
    • A non-peptide substance P antagonist down-regulates SP mRNA expression in human mononuclear phagocytes
    • LAI JP, HO WZ, YANG JH, WANG X, SONG L, DOUGLAS SD: A non-peptide substance P antagonist down-regulates SP mRNA expression in human mononuclear phagocytes. J. Neuroimmunol. (2002) 128:101-108.
    • (2002) J. Neuroimmunol. , vol.128 , pp. 101-108
    • Lai, J.P.1    Ho, W.Z.2    Yang, J.H.3    Wang, X.4    Song, L.5    Douglas, S.D.6
  • 215
    • 0035865194 scopus 로고    scopus 로고
    • Cloning of human preprotachykinin-I promoter and the role of cyclic adenosine 5′-monophosphate response elements in its expression by IL-1 and stem cell factor
    • QIAN J, YEHIA G, MOLINA CA et al.: Cloning of human preprotachykinin-I promoter and the role of cyclic adenosine 5′-monophosphate response elements in its expression by IL-1 and stem cell factor. J. Immunol. (2001) 166:2553-2561.
    • (2001) J. Immunol. , vol.166 , pp. 2553-2561
    • Qian, J.1    Yehia, G.2    Molina, C.A.3
  • 216
    • 0034602721 scopus 로고    scopus 로고
    • Increased expression of preprotachykinin-I and neurokinin receptors in human breast cancer cells: Implications for bone marrow metastasis
    • SINGH D, JOSHI DD, HAMEED M et al.: Increased expression of preprotachykinin-I and neurokinin receptors in human breast cancer cells: implications for bone marrow metastasis. Proc. Natl. Acad. Sci. USA (2001) 97:388-393.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 388-393
    • Singh, D.1    Joshi, D.D.2    Hameed, M.3
  • 217
    • 0037098917 scopus 로고    scopus 로고
    • Tachykinins and tachykinin receptors in bone
    • GOTO T, TANAKA T. Tachykinins and tachykinin receptors in bone. Microscopy Res. Tech. (2002) 58:91-97.
    • (2002) Microscopy Res. Tech. , vol.58 , pp. 91-97
    • Goto, T.1    Tanaka, T.2
  • 219
    • 0031895454 scopus 로고    scopus 로고
    • Neuropeptides in the skin: Interactions between the neuroendocrine and the skin immune system
    • SCHOLZEN T, ARMSTRONG CA, BUNNETT NW et al.: Neuropeptides in the skin: interactions between the neuroendocrine and the skin immune system. Exp. Dermatol. (1998) 7:81-96.
    • (1998) Exp. Dermatol. , vol.7 , pp. 81-96
    • Scholzen, T.1    Armstrong, C.A.2    Bunnett, N.W.3
  • 221
    • 0030200599 scopus 로고    scopus 로고
    • Tachykinin and kinin receptor antagonists: Therapeutic perspectives in allergy airway disease
    • BERTRAND C, GEPPETTI P: Tachykinin and kinin receptor antagonists: therapeutic perspectives in allergy airway disease. Trends Pharmacol Sci. (1996) 17:255-259.
    • (1996) Trends Pharmacol. Sci. , vol.17 , pp. 255-259
    • Bertrand, C.1    Geppetti, P.2
  • 222
    • 0029837011 scopus 로고    scopus 로고
    • The immunomodulation of enteric neuromuscular function: Implications for motility and inflammatory disorders
    • COLLINS SM: The immunomodulation of enteric neuromuscular function: implications for motility and inflammatory disorders. Gastroenterology (1996) 111:1683-1699.
    • (1996) Gastroenterology , vol.111 , pp. 1683-1699
    • Collins, S.M.1


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