Effects of nematode infection on sensitivity to intestinal distension: Role of tachykinin NK2 receptors

European Journal of Pharmacology

Volumn 337, Issue 2-3, 1997, Pages 279-282

  McLean, Peter G ^a   Picard, Céline ^a   Garcia Villar, Rafael ^a   Moré, Jean ^a   Fioramonti, Jean ^a   Buéno, Lionel ^a  

^a CEMAGREF   (France)

Author keywords

Intestinal distension; Mast cell; Tachykinin; Tachykinin NK2 receptor; Visceral hyperalgesia; Visceral nociception

Indexed keywords

SAREDUTANT; TACHYKININ; TACHYKININ RECEPTOR; TACHYKININ RECEPTOR ANTAGONIST;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENTERITIS; ETIOLOGY; HYPERALGESIA; HYPERSENSITIVITY; INTESTINE DISTENSION; IRRITABLE COLON; MALE; MAST CELL; NEMATODIASIS; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BENZAMIDES; COLON; COLONIC DISEASES; DILATATION, PATHOLOGIC; INTESTINAL DISEASES, PARASITIC; JEJUNAL DISEASES; JEJUNUM; MALE; MAST CELLS; NIPPOSTRONGYLUS; PAIN MEASUREMENT; PEROXIDASE; PIPERIDINES; RATS; RATS, WISTAR; RECEPTORS, NEUROKININ-2; STRONGYLIDA INFECTIONS;

EID: 0030709227     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(97)01275-2     Document Type: Article

References (18)

1. Bradley P.P., Priebat D.A., Christensen R.D., Rothstein G. Measurement of cutaneous inflammation: Estimation of neutrophil content with an enzyme marker. J. Invest. Dermatol. 78:1982;206-209.
2. 2) receptor. Life Sci. 50:1992;PL101-106.
3. Enerback L., Kolset S.O., Kusche M., Hjerpe A., Lindahl U. Glycosaminoglycans in rat mucosal mast cells. Biochem. J. 227:1985;661-668.
4. Evans P.R., Bennett E.J., Bak Y.T., Tennant C.C., Kellow J.E. Jejunal sensorimotor dysfunction in irritable bowel syndrome: Clinical and psychosocial features. Gastroenterology. 110:1996;393-404.
5. Julia V., Morteau O., Bueno L. Involvement of neurokinin 1 and 2 receptors in viscerosensitive response to rectal distension in rats. Gastroenterology. 107:1994;94-102.
6. Lembeck F., Skofitsch G. Visceral pain reflex after pretreatment with capsaicin and morphine. Naunyn-Schmiedeberg's Arch. Pharmacol. 321:1982;116-122.
7. Masson S.D., McKay D.M., Stead R.H., Agro A., Stanisz A., Perdue M.H. Nippostrongylus brasiliensis infection evokes neuronal abnormalities and alterations in neurally regulated electrolyte transport in rat jejunum. Parasitology. 113:1996;173-182.
8. Mayer, E.A., Raybould, H.E. (Eds.), 1993. Basic and Clinical Aspects of Chronic Abdominal Pain. Elsevier, New York, NY.
9. Moss H.E., Sanger G.J. The effects of granisetron, ICS 205-930 and ondansetron on the visceral pain reflex induced by duodenal distension. Br. J. Pharmacol. 100:1990;497-501.
10. Ness T.J., Gebhart G.F. Colorectal distension as a noxious visceral stimulus: Physiologic and pharmacologic characterization of pseudoaffective reflexes in the rat. Brain Res. 450:1988;153-169.
11. Ness T.J., Gebhart G.F. Visceral pain: A review of experimental studies. Pain. 41:1988;167-234.
12. Pang X., Boucher W., Triadafilopoulos G., Sant G.R., Theoharides T.C. Mast cell and substance P-positive nerve involvement in a patient with both irritable bowel syndrome and interstitial cystitis. Urology. 47:1996;436-438.
13. Poncelet M., Gueudet C., Emonds-Alt X., Breliere J.C., Le Fur G., Soubrie P. Turning behavior induced in mice by a neurokinin A receptor agonist: Stereoselective blockade by SR 48968, a non-peptide receptor antagonist. Neurosci. Lett. 149:1993;40-42.
14. Santucci V., Gueudet C., Edmonds-Alt X., Breliere J.C., Soubrie P., Le Fur G. The NK2 receptor antagonist SR 48968 inhibits thalamic responses evoked by thermal but not mechanical nociception. Eur. J. Pharmacol. 237:1993;143-146.
15. Seguin L., Le Marouille-Girardon S., Millan M.J. Antinociceptive profiles of non-peptidergic neurokinin1 and neurokinin2 receptor antagonists: A comparison to other classes of antinociceptive agent. Pain. 61:1995;325-343.
16. Stead R.H. Nerve remodelling during intestinal inflammation. Ann. N.Y. Acad. Sci. 664:1992;443-455.
17. Stead R.H., Dixon M.F., Bramwell N.H., Riddell R.H., Bienenstock J. Mast cells are closely apposed to nerves in the human gastrointestinal mucosa. Gastroenterology. 97:1989;575-585.
18. Weston A.P., Biddle W.L., Bhatia P.S., Miner Jr. P.B. Terminal ileal mucosal mast cells in irritable bowel syndrome. Dig. Dis. Sci. 38:1993;1590-1595.