Nerve growth factor-induced phenotypic switch in guinea pig airway sensory neurons

American Journal of Respiratory and Critical Care Medicine

Volumn 161, Issue 6, 2000, Pages 1985-1990

  Hunter, Dawn D ^a   Myers, Allen C ^a   Undem, Bradley J ^a,b  

^a DEPARTMENT OF PATHOLOGY   (United States)

^b JOHNS HOPKINS ASTHMA AND ALLERGY CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRADYKININ; CAPSAICIN; NERVE GROWTH FACTOR; SUBSTANCE P;

AIRWAY; ANIMAL EXPERIMENT; ARTICLE; CELL LABELING; CONTROLLED STUDY; GUINEA PIG; IMMUNOCYTOCHEMISTRY; IMMUNOREACTIVITY; MALE; NEUROFILAMENT; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SENSORY NERVE CELL; TRACHEA; VAGUS NERVE;

EID: 0034089114     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.161.6.9908051     Document Type: Article

References (19)

1. 1. Kummer, W., A. Fischer, R. Kurkowski, and C. Heym. 1992. The sensory and sympathetic innervation of guinea-pig lung and trachea as studied by retrograde neuronal tracing and double-labelling immunohistochemistry. Neurosci. 49:715-737.
2. 2. Riccio, M., W. Kummer, A. C. Myers, and B. J. Undem. 1996. Interganglionic segregation of airway vagal afferent fiber phenotypes. J. Physiol. 496:521-530.
3. 3. Hunter, D. D., and B. J. Undem. 1999. Identification and substance P content of vagal afferent neurons innervating the epithelium of the guinea pig trachea. Am. J. Respir. Crit. Care Med. 159:1-6.
4. 4. Pedersen, K. E., S. N. Meeker, M. M. Riccio, and B. J. Undem. 1998. Selective stimulation of jugular ganglion afferent neurons in guinea pig airways by hypertonic saline. J. Appl. Physiol. 84:499-506.
5. 5. Kajekar, R., and A. C. Myers. 1999. Bradykinin stimulates guinea pig bronchial parasympathetic ganglia neurons independent of sensory nerve stimulation (abstract). Am. J. Respir. Crit. Care Med. 159:A279.
6. 6. Galeazza, M. T., M. G. Garry, H. J. Yost, K. A. Strait, K. M. Hargreves, and V. S. Seybold. 1995. Plasticity in the synthesis and storage of substance P and calcitonin gene-related peptide in primary afferent neurons during peripheral inflammation. Neuroscience 66:443-458.
7. 7. Collins, S. M. 1996. The immunomodulation of enteric neuromuscular function: implications for motility and inflammatory disorders. Gastroenterology 111:1683-1699.
8. 8. Fujishima, H., M. Takeyama, T. Takeuchi, I. Saito, and K. Tsubota. 1997. Elevated levels of substance P in tears of patients with allergic conjunctivitis and vernal keratoconjunctivitis. Clin. Exp. Allergy 27: 372-378.
9. 9. Fischer, A., O. McGregor, A. Saria, B. Philippin, and W. Kummer. 1996. Induction of tachykinin gene and peptide expression in guinea pig no-dose primary afferent neurons by allergic inflammation. J. Clin. Invest. 98:2284-2291.
10. 10. Neumann, S., T. P. Doubell, T. Leslie, and C. J. Woolf. 1996. Inflammatory pain hypersensitivity mediated by phenotypic switch in myelinated primary sensory neurons. Nature 384:360-364.
11. 11. Braun, A., M. Lommatzsch, G. R. Lewin, J. C. Virchow, and H. Renz. 1999. Neurotrophins: a link between airway inflammation and airway smooth muscle contractility in asthma? Int. Arch. Allergy Immunol. 118:163-165.
12. 12. Sanico, A. M., V. E. Koliatsos, A. M. Stanisz, J. Bienenstock, and A. Togias. 1999. Neural hyperresponsiveness and nerve growth factor in allergic rhinitis. Int. Arch. Allergy Immunol. 118:154-158.
13. 13. Lindsay, R. M., and A. J. Harmar. 1989. Nerve growth factor regulates expression of neuropeptide genes in adult sensory neurons. Nature 337: 362-364.
14. 14. Zhuo, H., H. Ichikawa, and C. J. Helke. 1997. Neurochemistry of the no-dose ganglion. Prog. Neurobiol. 52:79-107.
15. 15. Lindsay, R. M., Y. A. Barde, A. M. Davies, and H. Rohrer. 1995. Differences and similarities in the neurotrophic growth factor requirements of sensory neurons derived from neural crest and neural placode. J. Cell. Sci. Suppl. 3:115-129.
16. 16. Springall, D. R., A. Cadieux, H. Oliveira, H. Su, D. Royston, and J. M. Polak. 1987. Retrograde tracing shows that CGRP-immunoreactive nerves of rat trachea and lung originate from vagal and dorsal root ganglia. J. Auton. Nerv. Syst. 20:155-166.
17. 17. Kajekar, R., D. Proud, S. N. Meeker, A. C. Myers, and B. J. Undem. 1999. Characteristics of vagal afferent subtypes stimulated by bradykinin in guinea pig trachea. J. Pharmacol. Exp. Ther. 289:682-687.
18. 18. Lawson, S. N., and P. J. Waddel. 1999. Soma neurofilament immunoreactivity is related to cell size and fibre conduction velocity in rat primary sensory neurons. J. Physiol. 435:41-63.
19. 19. McCarthy, P. W., and S. N. Lawson. 1989. Cell type and conduction velocity of rat primary sensory neurons with substance P-like immunoreactivity. Neuroscience 28:745-753.