Abnormal motility in patients with ulcerative colitis: The role of inflammatory cytokines

Archives of Surgery

Volumn 137, Issue 4, 2002, Pages 439-446

  Vrees, Matthew D ^a   Pricolo, Victor E ^a   Potenti, Fabio M ^a   Cao, Weibiao ^a  

^a BROWN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; HYDROGEN PEROXIDE; INTERLEUKIN 1BETA; NEUROKININ A; THAPSIGARGIN;

CALCIUM CELL LEVEL; CLINICAL ARTICLE; CONFERENCE PAPER; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN TISSUE; INTESTINE MOTILITY; MOTOR DYSFUNCTION; MUSCLE FUNCTION; PRIORITY JOURNAL; SIGMOID; SMOOTH MUSCLE; ULCERATIVE COLITIS;

ADENOSINE TRIPHOSPHATE; CALCIUM; COLITIS, ULCERATIVE; COLON; COLON, SIGMOID; COLONIC NEOPLASMS; CYTOSOL; ENZYME-LINKED IMMUNOSORBENT ASSAY; GASTROINTESTINAL MOTILITY; HUMANS; HYDROGEN PEROXIDE; INTERLEUKIN-1; MUSCLE CONTRACTION; MUSCLE, SMOOTH; NEUROKININ A; THAPSIGARGIN;

EID: 0036083475     PISSN: 00040010     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (63)

1. The motility of the distal colon in nonspecific ulcerative colitis
2. Observations on the pathological physiology of ulcerative colitis
3. Interleukin 1 beta (IL-1 beta) release from fresh and cultured colonic mucosa in patients with ulcerative colitis (UC)
4. Cytokines (immunoinflammatory hormones) and their natural regulation in inflammatory bowel disease (Crohn's disease and ulcerative colitis): A review
5. Increased interleukin 8 expression in the colon mucosa of patients with inflammatory bowel disease
6. Serum interleukin-6 is related to disease activity but not disease specificity in inflammatory bowel disease
7. Increased interleukin-8 (IL-8) in rectal dialysate from patients with ulcerative colitis: Evidence for a biological role for IL-8 in inflammation of the colon
8. Enhanced production of interleukin 1-beta by mononuclear cells isolated from mucosa with active ulcerative colitis of Crohn's disease
9. Enhanced synthesis of neutrophilactivating peptide-1/interleukin-8 in active ulcerative colitis
10. Expression of IL-8, TNF-alpha, and IFN-gamma m-RNA in ulcerative colitis, particularly in patients with inactive phase
11. Increased expression of IP-10, IL-8, MCP-1, and MCP-3 in ulcerative colitis
12. Cytokines and inflammatory bowel disease: A review
13. Colonic mucosal interleukin-6 in inflammatory bowel disease
14. IL-8 as an important chemoattractant for neutrophils in ulcerative colitis and Crohn's disease
15. Tumor necrosis factor-alpha, interleukin-1 beta, and interleukin-6 expression in inflammatory bowel disease
16. Lower esophageal sphincter mechanics: Anatomic and physiologic relationships of the esophagogastric junction of the cat
17. Gq-linked NK(2) receptors mediate neurally induced contraction of human sigmoid circular smooth muscle
18. Epidemiology and the natural course of inflammatory bowel disease
19. Novel therapies for inflammatory bowel disease
20. The germfree state prevents development of gut and joint inflammatory disease in HLA-B27 transgenic rats
21. CD4+ T cells reactive to enteric bacterial antigens in spontaneously colitic C3H/HeJBir mice: Increased T helper cell type 1 response and ability to transfer disease
22. Evidence for an increased risk of Crohn's disease in oral contraceptive users
23. Genetics versus environment in inflammatory bowel disease: Results of a British twin study
24. Defect in colonic smooth muscle contraction in patients with ulcerative colitis
25. Motility of the pelvic colon and rectum of normal persons and patients with ulcerative colitis
26. Spontaneous contractions and some electrophysiologic properties of circular muscle from normal sigmoid colon and ulcerative colitis
27. Colonic motility in ulcerative colitis after opiate administration
28. Effect of acute experimental colitis on rabbit colonic smooth muscle
29. Acute experimental colitis decreases colonic circular smooth muscle contractility in rats
30. Acute experimental distal colitis alters colonic transit in rats
31. Role of interleukin 1 in inflammatory bowel disease: Enhanced production during active disease
32. Imbalance of the interleukin 1 system in colonic mucosa: Association with intestinal inflammation and interleukin 1 receptor antagonist genotype 2
33. Mucosal expression of inteleukin-6 and interleukin-8 messenger RNA in ulcerative colitis and in Crohn's disease
34. Interleukin-1 in the pathogenesis of and protection from inflammatory bowel disease
35. Interleukin-1 and interleukin-1 receptor antagonist in inflammatory bowel disease
36. Production of inflammatory cytokines in the intestinal lamina propria
37. Serum interleukin-8 in inflammatory bowel disease
38. Impaired interleukin-2 production in active ulcerative colitis is reversed by calcium ionophore plus phorbol myristate acetate and related to altered intracellular Ca2+ responses
39. Roles of IL-1 and TNF in the decreased ileal muscle contractility induced by lipopolysaccharide
40. IL-10 synergizes with IL-4 and IL-13 in inhibiting lysosomal enzyme secretion by human monocytes and tamina propria mononuclear cells from patients with inflammatory bowel disease
41. Role of cytokines in inflammatory bowel disease
42. Expression of interleukin 1 beta and interleukin 1 beta converting enzyme by intestinal macrophages in health and inflammatory bowel disease
43. Increased in vitro release of soluble interleukin 2 receptor by colonic lamina propria mononuclear cells in inflammatory bowel disease
44. Interleukin-10 (IL-10) genotypes in inflammatory bowel disease
45. Synergistic regulation of NOS II expression by IL-1 beta and TNF-alpha in cultured rat colonic smooth muscle cells
46. Enhanced secretion of tumour necrosis factor-alpha, IL-6, and IL-1 beta by isolated lamina propria mononuclear cells from patients with ulcerative colitis and Crohn's disease
47. Enhanced mucosai cytokine production in inflammatory bowel disease
48. Receptors for mammalian tachykinins on isolated intestinal smooth muscle Cells
49. Tachykinins as transmitters of ascending contractile component of the peristaltic reflex
50. The human neurokinin A (substance K) receptor: Molecular cloning of the gene, chromosome localization, and isolation of cDNA from tracheal and gastric tissues
51. Occurrence, release, and effects of multiple tachykinins in cat colonic tissues and nerves
52. Coexistence of 3 tachykinin receptors coupled to Ca++ signaling pathways in intestinal muscle cells
53. Tachykinins contract the circular muscle of the human esophageal body in vitro via NK2 receptors
54. A novel motility effect of tachykinins in normal and inflamed colon
55. Down-regulation of L-type calcium channels in inflamed circular smooth muscle cells of the canine colon
56. Impairment of Ca(2+) mobilization in circular muscle cells of the inflamed colon
57. Inflammatory modulation of calcium-activated potassium channels in canine colonic circular smooth muscle cells
58. Inhibition of acetylcholine induced intestinal motility by interleukin 1 beta in the rat
59. Oxidants and free radicals in inflammatory bowel disease
60. Excessive production of reactive oxygen metabolites by inflamed colon: Analysis by chemiluminescence probe
61. Chemiluminescence assay of mucosal reactive oxygen metabolites in inflammatory bowel disease
62. Different types of contractions in rat colon and their modulation by oxidative stress
63. A new generation of Ca2+ indicators with greatly improved fluorescence properties