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Volumn 189, Issue 2, 2003, Pages 117-128

Ras superfamily monomeric G proteins in carcinoma cell motility

Author keywords

Basement membrane; Cdc42; Cell migration; Epithelial cells; Fibroblasts; Rac; Ral; Ras; Rho; Tumorigenesis

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; MONOMER; RAS PROTEIN; RHO FACTOR;

EID: 0037469079     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(02)00510-4     Document Type: Review
Times cited : (85)

References (114)
  • 1
    • 0035815923 scopus 로고    scopus 로고
    • Annual report to the nation on the status of cancer (1973 through 1998), featuring cancers with recent increasing trends
    • Howe H.L., Wingo P.A., Thun M.J., Ries L.A., Rosenberg H.M., Feigal E.G., Edwards B.K. Annual report to the nation on the status of cancer (1973 through 1998), featuring cancers with recent increasing trends. J. Natl. Cancer Inst. 93:2001;824-842.
    • (2001) J. Natl. Cancer Inst. , vol.93 , pp. 824-842
    • Howe, H.L.1    Wingo, P.A.2    Thun, M.J.3    Ries, L.A.4    Rosenberg, H.M.5    Feigal, E.G.6    Edwards, B.K.7
  • 3
    • 0035005758 scopus 로고    scopus 로고
    • Seed and soil revisited: Contribution of the organ microenvironment to cancer metastasis
    • vii-viiii
    • Fidler I.J. Seed and soil revisited: contribution of the organ microenvironment to cancer metastasis. Surg. Oncol. Clin. N. Am. 10:2001;257-269. vii-viiii.
    • (2001) Surg. Oncol. Clin. N. Am. , vol.10 , pp. 257-269
    • Fidler, I.J.1
  • 4
    • 0035902141 scopus 로고    scopus 로고
    • The microenvironment of the tumour-host interface
    • Liotta L.A., Kohn E.C. The microenvironment of the tumour-host interface. Nature. 411:2001;375-379.
    • (2001) Nature , vol.411 , pp. 375-379
    • Liotta, L.A.1    Kohn, E.C.2
  • 5
    • 0036595629 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in tumour progression
    • Thiery J.P. Epithelial-mesenchymal transitions in tumour progression. Nat. Rev. Cancer. 2:2002;442-454.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 442-454
    • Thiery, J.P.1
  • 6
    • 0037169868 scopus 로고    scopus 로고
    • Cadherins and the tumour progression: Is it all in a switch?
    • Cavallaro U., Schaffhauser B., Christofori G. Cadherins and the tumour progression: is it all in a switch? Cancer Lett. 176:2002;123-128.
    • (2002) Cancer Lett. , vol.176 , pp. 123-128
    • Cavallaro, U.1    Schaffhauser, B.2    Christofori, G.3
  • 7
    • 0036006814 scopus 로고    scopus 로고
    • Role of the hepatocyte growth factor receptor, c-Met, in oncogenesis and potential for therapeutic inhibition
    • Maulik G., Shrikhande A., Kijima T., Ma P.C., Morrison P.T., Salgia R. Role of the hepatocyte growth factor receptor, c-Met, in oncogenesis and potential for therapeutic inhibition. Cytokine Growth Factor Rev. 13:2002;41-59.
    • (2002) Cytokine Growth Factor Rev. , vol.13 , pp. 41-59
    • Maulik, G.1    Shrikhande, A.2    Kijima, T.3    Ma, P.C.4    Morrison, P.T.5    Salgia, R.6
  • 8
    • 0036512208 scopus 로고    scopus 로고
    • New functions for the matrix metalloproteinases in cancer progression
    • Egeblad M., Werb Z. New functions for the matrix metalloproteinases in cancer progression. Nat. Rev. Cancer. 2:2002;161-174.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 161-174
    • Egeblad, M.1    Werb, Z.2
  • 9
    • 0037192635 scopus 로고    scopus 로고
    • Complex roles of tissue inhibitors of metalloproteinases in cancer
    • Jiang Y., Goldberg I.D., Shi Y.E. Complex roles of tissue inhibitors of metalloproteinases in cancer. Oncogene. 21:2002;2245-2252.
    • (2002) Oncogene , vol.21 , pp. 2245-2252
    • Jiang, Y.1    Goldberg, I.D.2    Shi, Y.E.3
  • 11
    • 0034921007 scopus 로고    scopus 로고
    • Tumor suppressor PTEN: Modulator of cell signaling, growth, migration and apoptosis
    • Yamada K.M., Araki M. Tumor suppressor PTEN: modulator of cell signaling, growth, migration and apoptosis. J. Cell Sci. 114:2001;2375-2382.
    • (2001) J. Cell Sci. , vol.114 , pp. 2375-2382
    • Yamada, K.M.1    Araki, M.2
  • 12
    • 0033830725 scopus 로고    scopus 로고
    • Heparin-binding EGF-like growth factor: A juxtacrine growth factor
    • Iwamoto R., Mekada E. Heparin-binding EGF-like growth factor: a juxtacrine growth factor. Cytokine Growth Factor Rev. 11:2000;335-344.
    • (2000) Cytokine Growth Factor Rev. , vol.11 , pp. 335-344
    • Iwamoto, R.1    Mekada, E.2
  • 13
    • 0035824920 scopus 로고    scopus 로고
    • Integrin and growth factor receptor crosstalk
    • Eliceiri B.P. Integrin and growth factor receptor crosstalk. Circ. Res. 89:2001;1104-1110.
    • (2001) Circ. Res. , vol.89 , pp. 1104-1110
    • Eliceiri, B.P.1
  • 14
    • 0032731892 scopus 로고    scopus 로고
    • Tumor invasion: Role of growth factor-induced cell motility
    • Wells A. Tumor invasion: role of growth factor-induced cell motility. Adv. Cancer Res. 78:2000;31-101.
    • (2000) Adv. Cancer Res. , vol.78 , pp. 31-101
    • Wells, A.1
  • 15
    • 0035811020 scopus 로고    scopus 로고
    • The Abl interactor proteins localize to sites of actin polymerization at the tips of lamellipodia and filopodia
    • Stradal T., Courtney K.D., Rottner K., Hahne P., Small J.V., Pendergast A.M. The Abl interactor proteins localize to sites of actin polymerization at the tips of lamellipodia and filopodia. Curr. Biol. 11:2001;891-895.
    • (2001) Curr. Biol. , vol.11 , pp. 891-895
    • Stradal, T.1    Courtney, K.D.2    Rottner, K.3    Hahne, P.4    Small, J.V.5    Pendergast, A.M.6
  • 16
    • 0035896436 scopus 로고    scopus 로고
    • Scar/WAVE is localised at the tips of protruding lamellipodia in living cells
    • Hahne P., Sechi A., Benesch S., Small J.V. Scar/WAVE is localised at the tips of protruding lamellipodia in living cells. FEBS Lett. 492:2001;215-220.
    • (2001) FEBS Lett. , vol.492 , pp. 215-220
    • Hahne, P.1    Sechi, A.2    Benesch, S.3    Small, J.V.4
  • 17
    • 0035070418 scopus 로고    scopus 로고
    • Tumor cell invasion of model 3-dimensional matrices: Demonstration of migratory pathways, collagen disruption, and intercellular cooperation
    • Horino K., Kindezelskii A.L., Elner V.M., Hughes B.A., Petty H.R. Tumor cell invasion of model 3-dimensional matrices: demonstration of migratory pathways, collagen disruption, and intercellular cooperation. FASEB J. 15:2001;932-939.
    • (2001) FASEB J. , vol.15 , pp. 932-939
    • Horino, K.1    Kindezelskii, A.L.2    Elner, V.M.3    Hughes, B.A.4    Petty, H.R.5
  • 18
    • 0033947887 scopus 로고    scopus 로고
    • Transmembrane motility assay of transiently transfected cells by fluorescent cell counting and luciferase measurement
    • Gildea J.J., Harding M.A., Gulding K.M., Theodorescu D. Transmembrane motility assay of transiently transfected cells by fluorescent cell counting and luciferase measurement. Biotechniques. 29:2000;81-86.
    • (2000) Biotechniques , vol.29 , pp. 81-86
    • Gildea, J.J.1    Harding, M.A.2    Gulding, K.M.3    Theodorescu, D.4
  • 19
    • 0035208736 scopus 로고    scopus 로고
    • Modification of the Boyden chamber to improve uniformity of cell invasion of matrigel-coated membranes
    • Bloomfield K.L., Baldwin B.L., Harkin D.G., Tonissen K.F. Modification of the Boyden chamber to improve uniformity of cell invasion of matrigel-coated membranes. Biotechniques. 31:2001;1242-1246.
    • (2001) Biotechniques , vol.31 , pp. 1242-1246
    • Bloomfield, K.L.1    Baldwin, B.L.2    Harkin, D.G.3    Tonissen, K.F.4
  • 20
  • 21
    • 0034644115 scopus 로고    scopus 로고
    • Signaling pathways and cell mechanics involved in wound closure by epithelial cell sheets
    • Fenteany G., Janmey P.A., Stossel T.P. Signaling pathways and cell mechanics involved in wound closure by epithelial cell sheets. Curr. Biol. 10:2000;831-838.
    • (2000) Curr. Biol. , vol.10 , pp. 831-838
    • Fenteany, G.1    Janmey, P.A.2    Stossel, T.P.3
  • 22
    • 0033693870 scopus 로고    scopus 로고
    • Live dynamics of GFP-calponin: Isoform-specific modulation of the actin cytoskeleton and autoregulation by C-terminal sequences
    • Danninger C., Gimona M. Live dynamics of GFP-calponin: isoform-specific modulation of the actin cytoskeleton and autoregulation by C-terminal sequences. J. Cell Sci. 113:2000;3725-3736.
    • (2000) J. Cell Sci. , vol.113 , pp. 3725-3736
    • Danninger, C.1    Gimona, M.2
  • 24
    • 0030045346 scopus 로고    scopus 로고
    • Cell migration: A physically integrated molecular process
    • Lauffenburger D.A., Horwitz A.F. Cell migration: a physically integrated molecular process. Cell. 84:1996;359-369.
    • (1996) Cell , vol.84 , pp. 359-369
    • Lauffenburger, D.A.1    Horwitz, A.F.2
  • 25
    • 0036056156 scopus 로고    scopus 로고
    • Cancer cell motility; On the road from c-erbB-2 receptor steered signaling to actin reorganization
    • Feldner J.C., Brandt B.H. Cancer cell motility; on the road from c-erbB-2 receptor steered signaling to actin reorganization. Exp. Cell Res. 272:2002;93-108.
    • (2002) Exp. Cell Res. , vol.272 , pp. 93-108
    • Feldner, J.C.1    Brandt, B.H.2
  • 26
    • 0034650714 scopus 로고    scopus 로고
    • Signal transduction by G-proteins, rho-kinase and protein phosphatase to smooth muscle and non-muscle myosin II
    • Somlyo A.P., Somlyo A.V. Signal transduction by G-proteins, rho-kinase and protein phosphatase to smooth muscle and non-muscle myosin II. J. Physiol. 522:2000;177-185.
    • (2000) J. Physiol. , vol.522 , pp. 177-185
    • Somlyo, A.P.1    Somlyo, A.V.2
  • 27
    • 0036222784 scopus 로고    scopus 로고
    • Adhesion assembly, disassembly and turnover in migrating cells - Over and over and over again
    • Webb D.J., Parsons J.T., Horwitz A.F. Adhesion assembly, disassembly and turnover in migrating cells - Over and over and over again. Nat. Cell Biol. 4:2002;E97-E100.
    • (2002) Nat. Cell Biol. , vol.4
    • Webb, D.J.1    Parsons, J.T.2    Horwitz, A.F.3
  • 28
    • 0036168356 scopus 로고    scopus 로고
    • Cutting to the chase: Calpain proteases in cell motility
    • Glading A., Lauffenburger D.A., Wells A. Cutting to the chase: calpain proteases in cell motility. Trends Cell Biol. 12:2002;46-54.
    • (2002) Trends Cell Biol. , vol.12 , pp. 46-54
    • Glading, A.1    Lauffenburger, D.A.2    Wells, A.3
  • 29
    • 0035975972 scopus 로고    scopus 로고
    • Cell motility: ARNOand ARF6 at the cutting edge
    • Turner C.E., Brown M.C. Cell motility: ARNOand ARF6 at the cutting edge. Curr. Biol. 11:2001;R875-R877.
    • (2001) Curr. Biol. , vol.11
    • Turner, C.E.1    Brown, M.C.2
  • 30
  • 31
    • 0001139669 scopus 로고    scopus 로고
    • Ras pathways to cell cycle control and cell transformation
    • Malumbres M., Pellicer A. Ras pathways to cell cycle control and cell transformation. Front. Biosci. 3:1998;d887-d912.
    • (1998) Front. Biosci. , vol.3
    • Malumbres, M.1    Pellicer, A.2
  • 32
    • 0034104590 scopus 로고    scopus 로고
    • The Ras branch of small GTPases: Ras family members don't fall far from the tree
    • Reuther G.W., Der C.J. The Ras branch of small GTPases: Ras family members don't fall far from the tree. Curr. Opin. Cell Biol. 12:2000;157-165.
    • (2000) Curr. Opin. Cell Biol. , vol.12 , pp. 157-165
    • Reuther, G.W.1    Der, C.J.2
  • 33
    • 0035964458 scopus 로고    scopus 로고
    • Ras and Rho regulation of the cell cycle and oncogenesis
    • Pruitt K., Der C.J. Ras and Rho regulation of the cell cycle and oncogenesis. Cancer Lett. 171:2001;1-10.
    • (2001) Cancer Lett. , vol.171 , pp. 1-10
    • Pruitt, K.1    Der, C.J.2
  • 36
    • 0035575616 scopus 로고    scopus 로고
    • Rab GTPases: Specifying and deciphering organelle identity and function
    • Pfeffer S.R. Rab GTPases: specifying and deciphering organelle identity and function. Trends Cell Biol. 11:2001;487-491.
    • (2001) Trends Cell Biol. , vol.11 , pp. 487-491
    • Pfeffer, S.R.1
  • 37
    • 0035575518 scopus 로고    scopus 로고
    • Nucleocytoplasmic transport: Ran, beta and beyond
    • Kuersten S., Ohno M., Mattaj I.W. Nucleocytoplasmic transport: ran, beta and beyond. Trends Cell Biol. 11:2001;497-503.
    • (2001) Trends Cell Biol. , vol.11 , pp. 497-503
    • Kuersten, S.1    Ohno, M.2    Mattaj, I.W.3
  • 38
    • 0037075886 scopus 로고    scopus 로고
    • GTPase activating proteins: Critical regulators of intracellular signaling
    • Donovan S., Shannon K.M., Bollag G. GTPase activating proteins: critical regulators of intracellular signaling. Biochim. Biophys. Acta. 1602:2002;23-45.
    • (2002) Biochim. Biophys. Acta , vol.1602 , pp. 23-45
    • Donovan, S.1    Shannon, K.M.2    Bollag, G.3
  • 39
    • 0033179296 scopus 로고    scopus 로고
    • GEFs: Structural basis for their activation of small GTP-binding proteins
    • Cherfils J., Chardin P. GEFs: structural basis for their activation of small GTP-binding proteins. Trends Biochem. Sci. 24:1999;306-311.
    • (1999) Trends Biochem. Sci. , vol.24 , pp. 306-311
    • Cherfils, J.1    Chardin, P.2
  • 40
    • 0033058184 scopus 로고    scopus 로고
    • Rho guanine dissociation inhibitors: Pivotal molecules in cellular signalling
    • Olofsson B. Rho guanine dissociation inhibitors: pivotal molecules in cellular signalling. Cellular Signalling. 11:1999;545-554.
    • (1999) Cellular Signalling , vol.11 , pp. 545-554
    • Olofsson, B.1
  • 41
    • 0032481125 scopus 로고    scopus 로고
    • Nuclear transport factor p10/NTF2 functions as a Ran-GDP dissociation inhibitor (Ran-GDI)
    • Yamada M., Tachibana T., Imamoto N., Yoneda Y. Nuclear transport factor p10/NTF2 functions as a Ran-GDP dissociation inhibitor (Ran-GDI). Curr. Biol. 8:1998;1339-1342.
    • (1998) Curr. Biol. , vol.8 , pp. 1339-1342
    • Yamada, M.1    Tachibana, T.2    Imamoto, N.3    Yoneda, Y.4
  • 42
    • 0030446448 scopus 로고    scopus 로고
    • Structural insights into the function of the Rab GDI superfamily
    • Wu S.K., Zeng K., Wilson I.A., Balch W.E. Structural insights into the function of the Rab GDI superfamily. Trends Biochem. Sci. 21:1996;472-476.
    • (1996) Trends Biochem. Sci. , vol.21 , pp. 472-476
    • Wu, S.K.1    Zeng, K.2    Wilson, I.A.3    Balch, W.E.4
  • 43
    • 0035128451 scopus 로고    scopus 로고
    • Roles of Ran-GTP and Ran-GDP in precursor vesicle recruitment and fusion during nuclear envelope assembly in a human cell-free system
    • Zhang C., Clarke P.R. Roles of Ran-GTP and Ran-GDP in precursor vesicle recruitment and fusion during nuclear envelope assembly in a human cell-free system. Curr. Biol. 11:2001;208-212.
    • (2001) Curr. Biol. , vol.11 , pp. 208-212
    • Zhang, C.1    Clarke, P.R.2
  • 47
    • 0026002058 scopus 로고
    • P21 with a phenylalanine 28; Leucine mutation reacts normally with the GTPase activating protein GAP but nevertheless has transforming properties
    • Reinstein J., Schlichting I., Frech M., Goody R.S., Wittinghofer A. p21 with a phenylalanine 28; leucine mutation reacts normally with the GTPase activating protein GAP but nevertheless has transforming properties. J. Biol. Chem. 266:1991;17700-17706.
    • (1991) J. Biol. Chem. , vol.266 , pp. 17700-17706
    • Reinstein, J.1    Schlichting, I.2    Frech, M.3    Goody, R.S.4    Wittinghofer, A.5
  • 48
    • 0003000807 scopus 로고    scopus 로고
    • Tools of the trade: Use of dominant-inhibitory mutants of Ras-family GTPases
    • Feig L.A. Tools of the trade: use of dominant-inhibitory mutants of Ras-family GTPases. Nat. Cell Biol. 1:1999;E25-E27.
    • (1999) Nat. Cell Biol. , vol.1
    • Feig, L.A.1
  • 49
    • 0037134020 scopus 로고    scopus 로고
    • For stable expression of short interfering RNAs in mammalian cells
    • Brummelkamp T.R., Bernards R., Agami R., system A. for stable expression of short interfering RNAs in mammalian cells. Science. 296:2002;550-553.
    • (2002) Science , vol.296 , pp. 550-553
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3    System, A.4
  • 51
    • 0035523359 scopus 로고    scopus 로고
    • Actin' up: RhoB in cancer and apoptosis
    • Prendergast G.C. Actin' up: RhoB in cancer and apoptosis. Nat. Rev. Cancer. 1:2001;162-168.
    • (2001) Nat. Rev. Cancer , vol.1 , pp. 162-168
    • Prendergast, G.C.1
  • 53
    • 0033950864 scopus 로고    scopus 로고
    • Turning on ARF: The Sec7 family of guanine-nucleotide-exchange factors
    • Jackson C.L., Casanova J.E. Turning on ARF: the Sec7 family of guanine-nucleotide-exchange factors. Trends Cell Biol. 10:2000;60-67.
    • (2000) Trends Cell Biol. , vol.10 , pp. 60-67
    • Jackson, C.L.1    Casanova, J.E.2
  • 55
    • 0032939619 scopus 로고    scopus 로고
    • Rho GTPases are over-expressed in human tumors
    • Fritz G., Just I., Kaina B. Rho GTPases are over-expressed in human tumors. Int. J. Cancer. 81:1999;682-687.
    • (1999) Int. J. Cancer , vol.81 , pp. 682-687
    • Fritz, G.1    Just, I.2    Kaina, B.3
  • 56
    • 0036168355 scopus 로고    scopus 로고
    • Characterization of RhoC expression in benign and malignant breast disease: A potential new marker for small breast carcinomas with metastatic ability
    • Kleer C.G., van Golen K.L., Zhang Y., Wu Z.F., Rubin M.A., Merajver S.D. Characterization of RhoC expression in benign and malignant breast disease: a potential new marker for small breast carcinomas with metastatic ability. Am. J. Pathol. 160:2002;579-584.
    • (2002) Am. J. Pathol. , vol.160 , pp. 579-584
    • Kleer, C.G.1    Van Golen, K.L.2    Zhang, Y.3    Wu, Z.F.4    Rubin, M.A.5    Merajver, S.D.6
  • 59
    • 0033581944 scopus 로고    scopus 로고
    • Cloning of a novel human Rac1b splice variant with increased expression in colorectal tumors
    • Jordan P., Brazao R., Boavida M.G., Gespach C., Chastre E. Cloning of a novel human Rac1b splice variant with increased expression in colorectal tumors. Oncogene. 18:1999;6835-6839.
    • (1999) Oncogene , vol.18 , pp. 6835-6839
    • Jordan, P.1    Brazao, R.2    Boavida, M.G.3    Gespach, C.4    Chastre, E.5
  • 60
    • 0029827248 scopus 로고    scopus 로고
    • Transformation by Rho exchange factor oncogenes is mediated by activation of an integrin-dependent pathway
    • Schwartz M.A., Toksoz D., Khosravi-Far R. Transformation by Rho exchange factor oncogenes is mediated by activation of an integrin-dependent pathway. EMBO J. 15:1996;6525-6530.
    • (1996) EMBO J. , vol.15 , pp. 6525-6530
    • Schwartz, M.A.1    Toksoz, D.2    Khosravi-Far, R.3
  • 61
    • 0030429765 scopus 로고    scopus 로고
    • The VAV family of signal transduction molecules
    • Bustelo X.R. The VAV family of signal transduction molecules. Crit. Rev. Oncogen. 7:1996;65-88.
    • (1996) Crit. Rev. Oncogen. , vol.7 , pp. 65-88
    • Bustelo, X.R.1
  • 62
    • 0030943968 scopus 로고    scopus 로고
    • The GTPase and Rho GAP domains of p190, a tumor suppressor protein that binds the M(r) 120,000 Ras GAP, independently function as anti-Ras tumor suppressors
    • Wang D.Z., Nur E.K.M.S., Tikoo A., Montague W., Maruta H. The GTPase and Rho GAP domains of p190, a tumor suppressor protein that binds the M(r) 120,000 Ras GAP, independently function as anti-Ras tumor suppressors. Cancer Res. 57:1997;2478-2484.
    • (1997) Cancer Res. , vol.57 , pp. 2478-2484
    • Wang, D.Z.1    Nur, E.K.M.S.2    Tikoo, A.3    Montague, W.4    Maruta, H.5
  • 63
    • 0034842795 scopus 로고    scopus 로고
    • The relationship of BRMS1 and RhoGDI2 gene expression to metastatic potential in lineage related human bladder cancer cell lines
    • Seraj M.J., Harding M.A., Gildea J.J., Welch D.R., Theodorescu D. The relationship of BRMS1 and RhoGDI2 gene expression to metastatic potential in lineage related human bladder cancer cell lines. Clin. Exp. Metastasis. 18:2000;519-525.
    • (2000) Clin. Exp. Metastasis , vol.18 , pp. 519-525
    • Seraj, M.J.1    Harding, M.A.2    Gildea, J.J.3    Welch, D.R.4    Theodorescu, D.5
  • 64
    • 0032860424 scopus 로고    scopus 로고
    • Regulation of the cytoskeleton and cell adhesion by the Rho family GTPases in mammalian cells
    • Kaibuchi K., Kuroda S., Amano M. Regulation of the cytoskeleton and cell adhesion by the Rho family GTPases in mammalian cells. Annu. Rev. Biochem. 68:1999;459-486.
    • (1999) Annu. Rev. Biochem. , vol.68 , pp. 459-486
    • Kaibuchi, K.1    Kuroda, S.2    Amano, M.3
  • 65
    • 0034715885 scopus 로고    scopus 로고
    • Regulation and functions of Rho-associated kinase
    • Amano M., Fukata Y., Kaibuchi K. Regulation and functions of Rho-associated kinase. Exp. Cell Res. 261:2000;44-51.
    • (2000) Exp. Cell Res. , vol.261 , pp. 44-51
    • Amano, M.1    Fukata, Y.2    Kaibuchi, K.3
  • 66
    • 0033160196 scopus 로고    scopus 로고
    • Cooperation between mDia1 and ROCK in Rho-induced actin reorganization
    • Watanabe N., Kato T., Fujita A., Ishizaki T., Narumiya S. Cooperation between mDia1 and ROCK in Rho-induced actin reorganization. Nat. Cell Biol. 1:1999;136-143.
    • (1999) Nat. Cell Biol. , vol.1 , pp. 136-143
    • Watanabe, N.1    Kato, T.2    Fujita, A.3    Ishizaki, T.4    Narumiya, S.5
  • 67
    • 0032784388 scopus 로고    scopus 로고
    • Distinct actions and cooperative roles of ROCK and mDia in Rho small G protein-induced reorganization of the actin cytoskeleton in Madin-Darby canine kidney cells
    • Nakano K., Takaishi K., Kodama A., Mammoto A., Shiozaki H., Monden M., Takai Y. Distinct actions and cooperative roles of ROCK and mDia in Rho small G protein-induced reorganization of the actin cytoskeleton in Madin-Darby canine kidney cells. Mol. Biol. Cell. 10:1999;2481-2491.
    • (1999) Mol. Biol. Cell , vol.10 , pp. 2481-2491
    • Nakano, K.1    Takaishi, K.2    Kodama, A.3    Mammoto, A.4    Shiozaki, H.5    Monden, M.6    Takai, Y.7
  • 69
    • 0034707597 scopus 로고    scopus 로고
    • RhoA function in lamellae formation and migration is regulated by the alpha6beta4 integrin and cAMP metabolism
    • O'Connor K.L., Nguyen B.K., Mercurio A.M. RhoA function in lamellae formation and migration is regulated by the alpha6beta4 integrin and cAMP metabolism. J. Cell Biol. 148:2000;253-258.
    • (2000) J. Cell Biol. , vol.148 , pp. 253-258
    • O'Connor, K.L.1    Nguyen, B.K.2    Mercurio, A.M.3
  • 70
    • 0037023720 scopus 로고    scopus 로고
    • Cooperativity between the Ras-ERK and Rho-Rho kinase pathways in urokinase-type plasminogen activator-stimulated cell migration
    • Jo M., Thomas K.S., Somlyo A.V., Somlyo A.P., Gonias S.L. Cooperativity between the Ras-ERK and Rho-Rho kinase pathways in urokinase-type plasminogen activator-stimulated cell migration. J. Biol. Chem. 277:2002;12479-12485.
    • (2002) J. Biol. Chem. , vol.277 , pp. 12479-12485
    • Jo, M.1    Thomas, K.S.2    Somlyo, A.V.3    Somlyo, A.P.4    Gonias, S.L.5
  • 71
    • 0035874879 scopus 로고    scopus 로고
    • Inhibition of epidermal growth factor-induced RhoA translocation and invasion of human pancreatic cancer cells by 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors
    • Kusama T., Mukai M., Iwasaki T., Tatsuta M., Matsumoto Y., Akedo H., Nakamura H. Inhibition of epidermal growth factor-induced RhoA translocation and invasion of human pancreatic cancer cells by 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors. Cancer Res. 61:2001;4885-4891.
    • (2001) Cancer Res. , vol.61 , pp. 4885-4891
    • Kusama, T.1    Mukai, M.2    Iwasaki, T.3    Tatsuta, M.4    Matsumoto, Y.5    Akedo, H.6    Nakamura, H.7
  • 72
    • 0033561508 scopus 로고    scopus 로고
    • Overexpression of small GTP-binding protein RhoA promotes invasion of tumor cells
    • Yoshioka K., Nakamori S., Itoh K. Overexpression of small GTP-binding protein RhoA promotes invasion of tumor cells. Cancer Res. 59:1999;2004-2010.
    • (1999) Cancer Res. , vol.59 , pp. 2004-2010
    • Yoshioka, K.1    Nakamori, S.2    Itoh, K.3
  • 74
    • 0031877714 scopus 로고    scopus 로고
    • RhoE regulates actin cytoskeleton organization and cell migration
    • Guasch R.M., Scambler P., Jones G.E., Ridley A.J. RhoE regulates actin cytoskeleton organization and cell migration. Mol. Cell. Biol. 18:1998;4761-4771.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 4761-4771
    • Guasch, R.M.1    Scambler, P.2    Jones, G.E.3    Ridley, A.J.4
  • 76
    • 0036211023 scopus 로고    scopus 로고
    • Expression of ROCK-1 in human pancreatic cancer: Its down-regulation by morpholino oligo antisense can reduce the migration of pancreatic cancer cells in vitro
    • Kaneko K., Satoh K., Masamune A., Satoh A., Shimosegawa T. Expression of ROCK-1 in human pancreatic cancer: its down-regulation by morpholino oligo antisense can reduce the migration of pancreatic cancer cells in vitro. Pancreas. 24:2002;251-257.
    • (2002) Pancreas , vol.24 , pp. 251-257
    • Kaneko, K.1    Satoh, K.2    Masamune, A.3    Satoh, A.4    Shimosegawa, T.5
  • 77
    • 0032812619 scopus 로고    scopus 로고
    • Rho-kinase (ROK) promotes CD44v(3,8-10)-ankyrin interaction and tumor cell migration in metastatic breast cancer cells
    • Bourguignon L.Y., Zhu H., Shao L., Zhu D., Chen Y.W. Rho-kinase (ROK) promotes CD44v(3,8-10)-ankyrin interaction and tumor cell migration in metastatic breast cancer cells. Cell Motility Cytoskeleton. 43:1999;269-287.
    • (1999) Cell Motility Cytoskeleton , vol.43 , pp. 269-287
    • Bourguignon, L.Y.1    Zhu, H.2    Shao, L.3    Zhu, D.4    Chen, Y.W.5
  • 78
    • 0034601487 scopus 로고    scopus 로고
    • Genomic analysis of metastasis reveals an essential role for RhoC
    • Clark E.A., Golub T.R., Lander E.S., Hynes R.O. Genomic analysis of metastasis reveals an essential role for RhoC. Nature. 406:2000;532-535.
    • (2000) Nature , vol.406 , pp. 532-535
    • Clark, E.A.1    Golub, T.R.2    Lander, E.S.3    Hynes, R.O.4
  • 79
    • 0034667370 scopus 로고    scopus 로고
    • RhoC GTPase, a novel transforming oncogene for human mammary epithelial cells that partially recapitulates the inflammatory breast cancer phenotype
    • van Golen K.L., Wu Z.F., Qiao X.T., Bao L.W., Merajver S.D. RhoC GTPase, a novel transforming oncogene for human mammary epithelial cells that partially recapitulates the inflammatory breast cancer phenotype. Cancer Res. 60:2000;5832-5838.
    • (2000) Cancer Res. , vol.60 , pp. 5832-5838
    • Van Golen, K.L.1    Wu, Z.F.2    Qiao, X.T.3    Bao, L.W.4    Merajver, S.D.5
  • 80
    • 0036280716 scopus 로고    scopus 로고
    • Mitogen activated protein kinase pathway is involved in RhoC GTPase induced motility, invasion and angiogenesis in inflammatory breast cancer
    • van Golen K.L., Bao L.W., Pan Q., Miller F.R., Wu Z.F., Merajver S.D. Mitogen activated protein kinase pathway is involved in RhoC GTPase induced motility, invasion and angiogenesis in inflammatory breast cancer. Clin. Exp. Metastasis. 19:2002;301-311.
    • (2002) Clin. Exp. Metastasis , vol.19 , pp. 301-311
    • Van Golen, K.L.1    Bao, L.W.2    Pan, Q.3    Miller, F.R.4    Wu, Z.F.5    Merajver, S.D.6
  • 82
    • 0034865456 scopus 로고    scopus 로고
    • Rho GTPases and cell migration
    • Ridley A.J. Rho GTPases and cell migration. J. Cell Sci. 114:2001;2713-2722.
    • (2001) J. Cell Sci. , vol.114 , pp. 2713-2722
    • Ridley, A.J.1
  • 83
    • 0033577975 scopus 로고    scopus 로고
    • Interplay between Rac and Rho in the control of substrate contact dynamics
    • Rottner K., Hall A., Small J.V. Interplay between Rac and Rho in the control of substrate contact dynamics. Curr. Biol. 9:1999;640-648.
    • (1999) Curr. Biol. , vol.9 , pp. 640-648
    • Rottner, K.1    Hall, A.2    Small, J.V.3
  • 85
    • 0034253196 scopus 로고    scopus 로고
    • Small G-protein networks: Their crosstalk and signal cascades
    • Matozaki T., Nakanishi H., Takai Y. Small G-protein networks: their crosstalk and signal cascades. Cellular Signalling. 12:2000;515-524.
    • (2000) Cellular Signalling , vol.12 , pp. 515-524
    • Matozaki, T.1    Nakanishi, H.2    Takai, Y.3
  • 86
    • 0035930585 scopus 로고    scopus 로고
    • Protein kinase A regulates Rac and is required for the growth factor-stimulated migration of carcinoma cells
    • O'Connor K.L., Mercurio A.M. Protein kinase A regulates Rac and is required for the growth factor-stimulated migration of carcinoma cells. J. Biol. Chem. 276:2001;47895-47900.
    • (2001) J. Biol. Chem. , vol.276 , pp. 47895-47900
    • O'Connor, K.L.1    Mercurio, A.M.2
  • 87
    • 0036176123 scopus 로고    scopus 로고
    • Pitx2a expression alters actin-myosin cytoskeleton and migration of HeLa cells through Rho GTPase signaling
    • Wei Q., Adelstein R.S. Pitx2a expression alters actin-myosin cytoskeleton and migration of HeLa cells through Rho GTPase signaling. Mol. Biol. Cell. 13:2002;683-697.
    • (2002) Mol. Biol. Cell , vol.13 , pp. 683-697
    • Wei, Q.1    Adelstein, R.S.2
  • 88
    • 0035834754 scopus 로고    scopus 로고
    • Rac affects invasion of human renal cell carcinomas by up-regulating tissue inhibitor of metalloproteinases (TIMP)-1 and TIMP-2 expression
    • Engers R., Springer E., Michiels F., Collard J.G., Gabbert H.E. Rac affects invasion of human renal cell carcinomas by up-regulating tissue inhibitor of metalloproteinases (TIMP)-1 and TIMP-2 expression. J. Biol. Chem. 276:2001;41889-41897.
    • (2001) J. Biol. Chem. , vol.276 , pp. 41889-41897
    • Engers, R.1    Springer, E.2    Michiels, F.3    Collard, J.G.4    Gabbert, H.E.5
  • 89
    • 0035908493 scopus 로고    scopus 로고
    • Blocking oncogenic Ras signaling for cancer therapy
    • Adjei A.A. Blocking oncogenic Ras signaling for cancer therapy. J. Natl. Cancer Inst. 93:2001;1062-1074.
    • (2001) J. Natl. Cancer Inst. , vol.93 , pp. 1062-1074
    • Adjei, A.A.1
  • 90
    • 0025253945 scopus 로고
    • The role of ras and myc oncogenes in human solid tumours and their relevance in diagnosis and prognosis (review)
    • Field J.K., Spandidos D.A. The role of ras and myc oncogenes in human solid tumours and their relevance in diagnosis and prognosis (review). Anticancer Res. 10:1990;1-22.
    • (1990) Anticancer Res. , vol.10 , pp. 1-22
    • Field, J.K.1    Spandidos, D.A.2
  • 91
    • 0030598164 scopus 로고    scopus 로고
    • Transcriptional activation of H-rasK-ras and N-ras proto-oncogenes in human bladder tumors
    • Vageli D., Kiaris H., Delakas D., Anezinis P., Cranidis A., Spandidos D.A. Transcriptional activation of H-rasK-ras and N-ras proto-oncogenes in human bladder tumors. Cancer Lett. 107:1996;241-247.
    • (1996) Cancer Lett. , vol.107 , pp. 241-247
    • Vageli, D.1    Kiaris, H.2    Delakas, D.3    Anezinis, P.4    Cranidis, A.5    Spandidos, D.A.6
  • 92
    • 0036264815 scopus 로고    scopus 로고
    • The RASSF1A tumor suppressor blocks cell cycle progression and inhibits cyclin D1 accumulation
    • Shivakumar L., Minna J., Sakamaki T., Pestell R., White M.A. The RASSF1A tumor suppressor blocks cell cycle progression and inhibits cyclin D1 accumulation. Mol. Cell. Biol. 22:2002;4309-4318.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 4309-4318
    • Shivakumar, L.1    Minna, J.2    Sakamaki, T.3    Pestell, R.4    White, M.A.5
  • 93
    • 0035936783 scopus 로고    scopus 로고
    • NF1 tumor suppressor gene function: Narrowing the GAP
    • Cichowski K., Jacks T. NF1 tumor suppressor gene function: narrowing the GAP. Cell. 104:2001;593-604.
    • (2001) Cell , vol.104 , pp. 593-604
    • Cichowski, K.1    Jacks, T.2
  • 94
    • 0034644537 scopus 로고    scopus 로고
    • Ras and Rho GTPases: A family reunion
    • Bar-Sagi D., Hall A. Ras and Rho GTPases: a family reunion. Cell. 103:2000;227-238.
    • (2000) Cell , vol.103 , pp. 227-238
    • Bar-Sagi, D.1    Hall, A.2
  • 95
    • 0035844149 scopus 로고    scopus 로고
    • Differential activation of the Rac pathway by Ha-Ras and K-Ras
    • Walsh A.B., Bar-Sagi D. Differential activation of the Rac pathway by Ha-Ras and K-Ras. J. Biol. Chem. 276:2001;15609-15615.
    • (2001) J. Biol. Chem. , vol.276 , pp. 15609-15615
    • Walsh, A.B.1    Bar-Sagi, D.2
  • 97
    • 0034723310 scopus 로고    scopus 로고
    • Epidermal growth factor receptor activation of calpain is required for fibroblast motility and occurs via an ERK/MAP kinase signaling pathway
    • Glading A., Chang P., Lauffenburger D.A., Wells A. Epidermal growth factor receptor activation of calpain is required for fibroblast motility and occurs via an ERK/MAP kinase signaling pathway. J. Biol. Chem. 275:2000;2390-2398.
    • (2000) J. Biol. Chem. , vol.275 , pp. 2390-2398
    • Glading, A.1    Chang, P.2    Lauffenburger, D.A.3    Wells, A.4
  • 98
    • 0033620657 scopus 로고    scopus 로고
    • R-Ras signals through specific integrin alpha cytoplasmic domains to promote migration and invasion of breast epithelial cells
    • Keely P.J., Rusyn E.V., Cox A.D., Parise L.V. R-Ras signals through specific integrin alpha cytoplasmic domains to promote migration and invasion of breast epithelial cells. J. Cell Biol. 145:1999;1077-1088.
    • (1999) J. Cell Biol. , vol.145 , pp. 1077-1088
    • Keely, P.J.1    Rusyn, E.V.2    Cox, A.D.3    Parise, L.V.4
  • 100
    • 0033965252 scopus 로고    scopus 로고
    • Hepatocyte growth factor modulates motility and invasiveness of ovarian carcinomas via Ras-mediated pathway
    • Ueoka Y., Kato K., Kuriaki Y., Horiuchi S., Terao Y., Nishida J., Ueno H., Wake N. Hepatocyte growth factor modulates motility and invasiveness of ovarian carcinomas via Ras-mediated pathway. Br. J. Cancer. 82:2000;891-899.
    • (2000) Br. J. Cancer , vol.82 , pp. 891-899
    • Ueoka, Y.1    Kato, K.2    Kuriaki, Y.3    Horiuchi, S.4    Terao, Y.5    Nishida, J.6    Ueno, H.7    Wake, N.8
  • 101
    • 0033549558 scopus 로고    scopus 로고
    • Myosin light chain kinase functions downstream of Ras/ERK to promote migration of urokinase-type plasminogen activator-stimulated cells in an integrin-selective manner
    • Nguyen D.H., Catling A.D., Webb D.J., Sankovic M., Walker L.A., Somlyo A.V., Weber M.J., Gonias S.L. Myosin light chain kinase functions downstream of Ras/ERK to promote migration of urokinase-type plasminogen activator-stimulated cells in an integrin-selective manner. J. Cell Biol. 146:1999;149-164.
    • (1999) J. Cell Biol. , vol.146 , pp. 149-164
    • Nguyen, D.H.1    Catling, A.D.2    Webb, D.J.3    Sankovic, M.4    Walker, L.A.5    Somlyo, A.V.6    Weber, M.J.7    Gonias, S.L.8
  • 102
    • 0030733653 scopus 로고    scopus 로고
    • Inhibition of growth and invasive activity of human pancreatic cancer cells by a farnesyltransferase inhibitor, manumycin
    • Kainuma O., Asano T., Hasegawa M., Kenmochi T., Nakagohri T., Tokoro Y., Isono K. Inhibition of growth and invasive activity of human pancreatic cancer cells by a farnesyltransferase inhibitor, manumycin. Pancreas. 15:1997;379-383.
    • (1997) Pancreas , vol.15 , pp. 379-383
    • Kainuma, O.1    Asano, T.2    Hasegawa, M.3    Kenmochi, T.4    Nakagohri, T.5    Tokoro, Y.6    Isono, K.7
  • 105
    • 0034899045 scopus 로고    scopus 로고
    • Signal pathways which promote invasion and metastasis: Critical and distinct contributions of extracellular signal-regulated kinase and Ral-specific guanine exchange factor pathways
    • Ward Y., Wang W., Woodhouse E., Linnoila I., Liotta L., Kelly K. Signal pathways which promote invasion and metastasis: critical and distinct contributions of extracellular signal-regulated kinase and Ral-specific guanine exchange factor pathways. Mol. Cell. Biol. 21:2001;5958-5969.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 5958-5969
    • Ward, Y.1    Wang, W.2    Woodhouse, E.3    Linnoila, I.4    Liotta, L.5    Kelly, K.6
  • 106
    • 0034771776 scopus 로고    scopus 로고
    • Signalling roles of mammalian phospholipase D1 and D2
    • Cockcroft S. Signalling roles of mammalian phospholipase D1 and D2. Cellul. Mol. Life Sci. 58:2001;1674-1687.
    • (2001) Cellul. Mol. Life Sci. , vol.58 , pp. 1674-1687
    • Cockcroft, S.1
  • 108
    • 0035159121 scopus 로고    scopus 로고
    • Role for phospholipase D in receptor-mediated endocytosis
    • Shen Y., Xu L., Foster D.A. Role for phospholipase D in receptor-mediated endocytosis. Mol. Cell. Biol. 21:2001;595-602.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 595-602
    • Shen, Y.1    Xu, L.2    Foster, D.A.3
  • 109
    • 0035817625 scopus 로고    scopus 로고
    • Activation of ARF6 by ARNO stimulates epithelial cell migration through downstream activation of both Rac1 and phospholipase D
    • Santy L.C., Casanova J.E. Activation of ARF6 by ARNO stimulates epithelial cell migration through downstream activation of both Rac1 and phospholipase D. J. Cell Biol. 154:2001;599-610.
    • (2001) J. Cell Biol. , vol.154 , pp. 599-610
    • Santy, L.C.1    Casanova, J.E.2
  • 110
    • 0035801516 scopus 로고    scopus 로고
    • An essential role for ARF6-regulated membrane traffic in adherens junction turnover and epithelial cell migration
    • Palacios F., Price L., Schweitzer J., Collard J.G., D'Souza-Schorey C. An essential role for ARF6-regulated membrane traffic in adherens junction turnover and epithelial cell migration. EMBO J. 20:2001;4973-4986.
    • (2001) EMBO J. , vol.20 , pp. 4973-4986
    • Palacios, F.1    Price, L.2    Schweitzer, J.3    Collard, J.G.4    D'Souza-Schorey, C.5
  • 111
    • 0036608158 scopus 로고    scopus 로고
    • Ras family therapy: Rab Rho and Ral talk to the exocyst
    • Novick P., Guo W. Ras family therapy: Rab Rho and Ral talk to the exocyst. Trends Cell Biol. 12:2002;247-249.
    • (2002) Trends Cell Biol. , vol.12 , pp. 247-249
    • Novick, P.1    Guo, W.2
  • 113
    • 0035442412 scopus 로고    scopus 로고
    • The use of FRET imaging microscopy to detect protein-protein interactions and protein conformational changes in vivo
    • Truong K., Ikura M. The use of FRET imaging microscopy to detect protein-protein interactions and protein conformational changes in vivo. Curr. Opin. Struct. Biol. 11:2001;573-578.
    • (2001) Curr. Opin. Struct. Biol. , vol.11 , pp. 573-578
    • Truong, K.1    Ikura, M.2
  • 114
    • 0035019920 scopus 로고    scopus 로고
    • Towards a mechanistic understanding of tumor invasion-lessons from the alpha6beta 4 integrin
    • Mercurio A.M., Rabinovitz I. Towards a mechanistic understanding of tumor invasion-lessons from the alpha6beta 4 integrin. Semin. Biol. 11:2001;129-141.
    • (2001) Semin. Biol. , vol.11 , pp. 129-141
    • Mercurio, A.M.1    Rabinovitz, I.2


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