-
1
-
-
0028171267
-
Expression of β1B integrin isoform in CHO cells results in a dominant negative effect on cell adhesion and motility
-
Balzac, F., S.F. Retta, A. Albini, A. Melchiorri, V.E. Koteliansky, M. Geuna, L. Silengo, and G. Tarone. 1994. Expression of β1B integrin isoform in CHO cells results in a dominant negative effect on cell adhesion and motility. J. Cell Biol. 127:557-565.
-
(1994)
J. Cell Biol.
, vol.127
, pp. 557-565
-
-
Balzac, F.1
Retta, S.F.2
Albini, A.3
Melchiorri, A.4
Koteliansky, V.E.5
Geuna, M.6
Silengo, L.7
Tarone, G.8
-
2
-
-
0032510978
-
Protein kinase C-alpha activity inversely modulates invasion and growth of intestinal cells
-
Batlle, E., J. Verdu, D. Dominguez, M. del Mont Llosad, V. Diaz, N. Loukili, R. Paciucci, F. Alameda, and A.G. de Herreros. 1998. Protein kinase C-alpha activity inversely modulates invasion and growth of intestinal cells. J. Biol. Chem. 273:15091-15098.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 15091-15098
-
-
Batlle, E.1
Verdu, J.2
Dominguez, D.3
Del Mont Llosad, M.4
Diaz, V.5
Loukili, N.6
Paciucci, R.7
Alameda, F.8
De Herreros, A.G.9
-
3
-
-
0031952651
-
Are changes in integrin affinity and conformation overemphasized?
-
Bazzoni, G., and M.E. Hemler. 1998. Are changes in integrin affinity and conformation overemphasized? Trends Biochem. Sci. 23:30-34.
-
(1998)
Trends Biochem. Sci.
, vol.23
, pp. 30-34
-
-
Bazzoni, G.1
Hemler, M.E.2
-
4
-
-
0029731588
-
Focal adhesions, contractility, and signaling
-
Burridge, K., and M. Chrzanowska-Wodnicka. 1996. Focal adhesions, contractility, and signaling. Annu. Rev. Cell Dev. Biol. 12:463-519.
-
(1996)
Annu. Rev. Cell Dev. Biol.
, vol.12
, pp. 463-519
-
-
Burridge, K.1
Chrzanowska-Wodnicka, M.2
-
5
-
-
0026596337
-
Distinct cellular functions mediated by different VLA inlegrin α subunit cytoplasmic domains
-
Chan, B.M., P.D. Kassner, J.A. Schiro, H.R. Byers, T.S. Kupper, and M.E. Hemler. 1992. Distinct cellular functions mediated by different VLA inlegrin α subunit cytoplasmic domains. Cell. 68:1051-1060.
-
(1992)
Cell
, vol.68
, pp. 1051-1060
-
-
Chan, B.M.1
Kassner, P.D.2
Schiro, J.A.3
Byers, H.R.4
Kupper, T.S.5
Hemler, M.E.6
-
6
-
-
0027939187
-
Integrin-mediated cell adhesion activates mitogen-activated protein kinases
-
Chen, Q., M.S. Kinch, T.H. Lin, K. Burridge, and R.L. Juliano. 1994. Integrin-mediated cell adhesion activates mitogen-activated protein kinases. J. Biol. Chem. 269:26602-26605.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 26602-26605
-
-
Chen, Q.1
Kinch, M.S.2
Lin, T.H.3
Burridge, K.4
Juliano, R.L.5
-
7
-
-
0029994358
-
Integrin-mediated activation of mitogen-activated protein (MAP) or extracellular signal-related kinase kinase (MEK) is independent of Ras
-
Chen, Q., T.H. Lin, C.J. Der, and R.L. Juliano. 1996. Integrin-mediated activation of mitogen-activated protein (MAP) or extracellular signal-related kinase kinase (MEK) is independent of Ras. J. Biol. Chem. 271:18122-18127.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 18122-18127
-
-
Chen, Q.1
Lin, T.H.2
Der, C.J.3
Juliano, R.L.4
-
8
-
-
0028174243
-
"Inside-out" signal transduction inhibited by isolated integrin cytoplasmic domains
-
Chen, Y.P., T.E. O'Toole, T. Shipley, J. Forsyth, S.E. LaFlamme, K.M. Yamada, S.J. Shattil, and M.H. Ginsberg. 1994. "Inside-out" signal transduction inhibited by isolated integrin cytoplasmic domains. J. Biol. Chem. 269: 18307-18310.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 18307-18310
-
-
Chen, Y.P.1
O'Toole, T.E.2
Shipley, T.3
Forsyth, J.4
LaFlamme, S.E.5
Yamada, K.M.6
Shattil, S.J.7
Ginsberg, M.H.8
-
9
-
-
0028987936
-
Integrins and signal transduction pathways: The road taken
-
Clark, E., and J.S. Brugge. 1995. Integrins and signal transduction pathways: the road taken. Science. 268:233-239.
-
(1995)
Science
, vol.268
, pp. 233-239
-
-
Clark, E.1
Brugge, J.S.2
-
10
-
-
17544364168
-
Ras activation is necessary for integrin-mediated activation of extracellular signal-regulated kinase 2 and cytosolic phospholipase A2 but not for cytoskeletal organization
-
Clark, E.A., and R.O. Hynes. 1996. Ras activation is necessary for integrin-mediated activation of extracellular signal-regulated kinase 2 and cytosolic phospholipase A2 but not for cytoskeletal organization. J. Biol. Chem. 271: 14814-14818.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 14814-14818
-
-
Clark, E.A.1
Hynes, R.O.2
-
11
-
-
0032572557
-
Integrin-mediated signals regulated by members of the Rho family of GTPases
-
Clark, E.A., W.G. King, J.S. Brugge, M. Symons, and R.O. Hynes. 1998. Integrin-mediated signals regulated by members of the Rho family of GTPases. J. Cell Biol. 142:573-586.
-
(1998)
J. Cell Biol.
, vol.142
, pp. 573-586
-
-
Clark, E.A.1
King, W.G.2
Brugge, J.S.3
Symons, M.4
Hynes, R.O.5
-
12
-
-
0030061450
-
Overexpression of the Ras-related TC21/R-Ras2 protein may contribute to the development of human breast cancers
-
Clark, G.J., M.S. Kinch, T.M. Gilmer, K. Burridge, and C.J. Der. 1996. Overexpression of the Ras-related TC21/R-Ras2 protein may contribute to the development of human breast cancers. Oncogene. 12:169-176.
-
(1996)
Oncogene
, vol.12
, pp. 169-176
-
-
Clark, G.J.1
Kinch, M.S.2
Gilmer, T.M.3
Burridge, K.4
Der, C.J.5
-
13
-
-
0028113884
-
R-Ras induces malignant, but not morphologic, transformation of NIH3T3 cells
-
Cox, A.D., T.R. Brtva, D.G. Lowe, and C.J. Der. 1994. R-Ras induces malignant, but not morphologic, transformation of NIH3T3 cells. Oncogene. 9:3281-3288.
-
(1994)
Oncogene
, vol.9
, pp. 3281-3288
-
-
Cox, A.D.1
Brtva, T.R.2
Lowe, D.G.3
Der, C.J.4
-
14
-
-
0032173443
-
Beta-1 integrin cytoplasmic domain regulates the constitutive conformation detected by Mab 15/7, but not the ligand-induced conformation
-
Crommie, D., and M.E. Hemler. 1998. Beta-1 integrin cytoplasmic domain regulates the constitutive conformation detected by Mab 15/7, but not the ligand-induced conformation. J. Cell. Biochem. 71:63-73.
-
(1998)
J. Cell. Biochem.
, vol.71
, pp. 63-73
-
-
Crommie, D.1
Hemler, M.E.2
-
15
-
-
0030845282
-
Dissection of pathways implicated in integrin-mediated actin cytoskeleton assembly
-
Defilippi, P., M. Venturino, D. Gulino, A. Duperray, P. Boquet, C. Fiorentini, G. Volpe, M. Palmeieri, L. Silengo, and G. Tarone. 1997. Dissection of pathways implicated in integrin-mediated actin cytoskeleton assembly. J. Biol. Chem. 272:21726-21734.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 21726-21734
-
-
Defilippi, P.1
Venturino, M.2
Gulino, D.3
Duperray, A.4
Boquet, P.5
Fiorentini, C.6
Volpe, G.7
Palmeieri, M.8
Silengo, L.9
Tarone, G.10
-
16
-
-
0030889991
-
The lipid products of phosphoinositide 3-kinase increase cell motility through protein kinase C
-
Derman, M.P., A. Toker, J.H. Hartwig, K. Spokes, J.R. Falck, C.S. Chen, L.C. Cantley, and L.G. Cantley. 1997. The lipid products of phosphoinositide 3-kinase increase cell motility through protein kinase C. J. Biol. Chem. 272: 6465-6470.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 6465-6470
-
-
Derman, M.P.1
Toker, A.2
Hartwig, J.H.3
Spokes, K.4
Falck, J.R.5
Chen, C.S.6
Cantley, L.C.7
Cantley, L.G.8
-
17
-
-
0029826174
-
Trans-dominant inhibition of integrin function
-
Diaz-Gonzalez, F., J. Forsyth, B. Steiner, and M.H. Ginsberg. 1996. Trans-dominant inhibition of integrin function. Mol. Biol. Cell. 7:1939-1951.
-
(1996)
Mol. Biol. Cell
, vol.7
, pp. 1939-1951
-
-
Diaz-Gonzalez, F.1
Forsyth, J.2
Steiner, B.3
Ginsberg, M.H.4
-
18
-
-
0029166667
-
A synthetic inhibitor of the mitogen-activated protein kinase cascade
-
Dudley, D.T., L. Pang, S.J. Decker, A.J. Bridges, and A.R. Saltiel. 1995. A synthetic inhibitor of the mitogen-activated protein kinase cascade. Proc. Natl. Acad. Sci. USA. 92:7686-7689.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 7686-7689
-
-
Dudley, D.T.1
Pang, L.2
Decker, S.J.3
Bridges, A.J.4
Saltiel, A.R.5
-
19
-
-
0030710958
-
Complementation of dominant suppression implicates CD98 in integrin activation
-
Fenczik, C.A., T. Sethi, J.W. Ramos, P.E. Hughes, and M.H. Ginsberg. 1997. Complementation of dominant suppression implicates CD98 in integrin activation. Nature. 390:81-85.
-
(1997)
Nature
, vol.390
, pp. 81-85
-
-
Fenczik, C.A.1
Sethi, T.2
Ramos, J.W.3
Hughes, P.E.4
Ginsberg, M.H.5
-
20
-
-
0031466275
-
Lysophosphatidic acid induces threonine phosphorylation of Tiam-1 in Swiss 3T3 fibroblasts via activation of protein kinase C
-
Fleming, I.N., C.M. Elliott, J.G. Collard, and J.H. Exton. 1997. Lysophosphatidic acid induces threonine phosphorylation of Tiam-1 in Swiss 3T3 fibroblasts via activation of protein kinase C.J. Biol. Chem. 272:33105-33110.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 33105-33110
-
-
Fleming, I.N.1
Elliott, C.M.2
Collard, J.G.3
Exton, J.H.4
-
21
-
-
0029843339
-
TC21 causes transformation by Raf-independent signaling pathways
-
Graham, S.M., A.B. Vojtek, S.Y. Huff, A.D. Cox, G.J. Clark, J.A. Cooper, and C.J. Der. 1996. TC21 causes transformation by Raf-independent signaling pathways. Mol. Cell. Biol. 16:6132-6140.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 6132-6140
-
-
Graham, S.M.1
Vojtek, A.B.2
Huff, S.Y.3
Cox, A.D.4
Clark, G.J.5
Cooper, J.A.6
Der, C.J.7
-
22
-
-
0025605064
-
Recognition of the A chain COOH-terminal heparin binding region of fibronectin involves multiple sites: Two contiguous sequences act independently to promote neural cell adhesion
-
Haugen, P.K., J.B. McCarthy, A.P Skubilz, L.T. Furcht, and P.C. Letourneau. 1990. Recognition of the A chain COOH-terminal heparin binding region of fibronectin involves multiple sites: two contiguous sequences act independently to promote neural cell adhesion. J. Cell Biol. 111:2733-2745.
-
(1990)
J. Cell Biol.
, vol.111
, pp. 2733-2745
-
-
Haugen, P.K.1
McCarthy, J.B.2
Skubilz, A.P.3
Furcht, L.T.4
Letourneau, P.C.5
-
23
-
-
0029913467
-
Differential interaction of the ras family GTP-binding proteins H-Ras, Rap1A and R-Ras with the putative effector molecules Raf kinase and Ral-guanine nucleotide exchange factor
-
Herrmann, C., G. Horn, M. Spaargaren, and A. Wittinghofer. 1996. Differential interaction of the ras family GTP-binding proteins H-Ras, Rap1A and R-Ras with the putative effector molecules Raf kinase and Ral-guanine nucleotide exchange factor. J. Biol. Chem. 271:6794-6800.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 6794-6800
-
-
Herrmann, C.1
Horn, G.2
Spaargaren, M.3
Wittinghofer, A.4
-
24
-
-
0029562867
-
The assembly of integrin adhesion complexes requires both extracellular matrix and intracellular rho/rac GTPases
-
Hotchin, N. A., and A. Hall. 1995. The assembly of integrin adhesion complexes requires both extracellular matrix and intracellular rho/rac GTPases. J. Cell Biol. 131:1857-1865.
-
(1995)
J. Cell Biol.
, vol.131
, pp. 1857-1865
-
-
Hotchin, N.A.1
Hall, A.2
-
25
-
-
0032054309
-
Integrin signaling and cell growth control
-
Howe, A., A.E. Aplin, S.K. Alahari, and R.L. Juliano. 1998. Integrin signaling and cell growth control. Curr. Opin. Cell Biol. 10:220-231.
-
(1998)
Curr. Opin. Cell Biol.
, vol.10
, pp. 220-231
-
-
Howe, A.1
Aplin, A.E.2
Alahari, S.K.3
Juliano, R.L.4
-
26
-
-
0032538449
-
Distinct mechanisms mediate the initial and sustained phases of integrin-mediated activation of the Raf/MEK/mitogen-activated protein kinase cascade
-
Howe, A.K., and R.L. Juliano. 1998. Distinct mechanisms mediate the initial and sustained phases of integrin-mediated activation of the Raf/MEK/mitogen-activated protein kinase cascade. J. Biol. Chem. 273:27268-27274.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 27268-27274
-
-
Howe, A.K.1
Juliano, R.L.2
-
27
-
-
0028918408
-
Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase
-
Hu, O., A. Klippel, A. Muslin, W. Fantl, and L. Williams. 1995. Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase. Science. 268:100-102.
-
(1995)
Science
, vol.268
, pp. 100-102
-
-
Hu, O.1
Klippel, A.2
Muslin, A.3
Fantl, W.4
Williams, L.5
-
28
-
-
0031024083
-
R-Ras is regulated by activators and effectors distinct from those that control Ras function
-
Huff, S.Y., L.A. Quilliam, A.D. Cox, and C.J. Der. 1997. R-Ras is regulated by activators and effectors distinct from those that control Ras function. Oncogene. 14:133-143.
-
(1997)
Oncogene
, vol.14
, pp. 133-143
-
-
Huff, S.Y.1
Quilliam, L.A.2
Cox, A.D.3
Der, C.J.4
-
29
-
-
0030909050
-
Suppression of integrin activation: A novel function of a Ras/Raf-initiated MAP kinase pathway
-
Hughes, P.E., M.W. Renshaw, M. Pfaff, J. Forsyth, V.M. Keivens, M.A. Schwartz, and M.H. Ginsberg. 1997. Suppression of integrin activation: a novel function of a Ras/Raf-initiated MAP kinase pathway. Cell. 88:521-530.
-
(1997)
Cell
, vol.88
, pp. 521-530
-
-
Hughes, P.E.1
Renshaw, M.W.2
Pfaff, M.3
Forsyth, J.4
Keivens, V.M.5
Schwartz, M.A.6
Ginsberg, M.H.7
-
30
-
-
0023223464
-
Identification of two distinct regions of the type III connecting segment of human plasma fibronectin that promote cell type-specific adhesion
-
Humphries, M.J., A. Komoriya, S.K. Akiyama, K. Olden, and K.M. Yamada. 1987. Identification of two distinct regions of the type III connecting segment of human plasma fibronectin that promote cell type-specific adhesion. J. Biol. Chem. 262:6886-6892.
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 6886-6892
-
-
Humphries, M.J.1
Komoriya, A.2
Akiyama, S.K.3
Olden, K.4
Yamada, K.M.5
-
31
-
-
0025301473
-
Collagen-induced platelet activation mainly involves the protein kinase C pathway
-
Karniguian, A., F. Grelac, S. Levy-Toledano, Y.J. Legrand, and F. Rendu. 1990. Collagen-induced platelet activation mainly involves the protein kinase C pathway. Biochem J. 268:325-331.
-
(1990)
Biochem J.
, vol.268
, pp. 325-331
-
-
Karniguian, A.1
Grelac, F.2
Levy-Toledano, S.3
Legrand, Y.J.4
Rendu, F.5
-
32
-
-
0028170368
-
Integrin α2 cytoplasmic domain deletion effects: Loss of adhesive activity parallels ligand-independent recruitment into focal adhesions
-
Kawaguchi, S., J.M. Bergelson, R.W. Finberg, and M.E. Hemler. 1994. Integrin α2 cytoplasmic domain deletion effects: loss of adhesive activity parallels ligand-independent recruitment into focal adhesions. Mol. Biol. Cell. 5:977-988.
-
(1994)
Mol. Biol. Cell
, vol.5
, pp. 977-988
-
-
Kawaguchi, S.1
Bergelson, J.M.2
Finberg, R.W.3
Hemler, M.E.4
-
33
-
-
0028918625
-
Alteration of collagen-dependent adhesion, motility, and morphogenesis by the expression of anti-sense α2 integrin mRNA in mammary cells
-
Keely, P., A. Fong, M. Zutter, and S. Santoro. 1995. Alteration of collagen-dependent adhesion, motility, and morphogenesis by the expression of anti-sense α2 integrin mRNA in mammary cells. J. Cell Sci. 108:595-607.
-
(1995)
J. Cell Sci.
, vol.108
, pp. 595-607
-
-
Keely, P.1
Fong, A.2
Zutter, M.3
Santoro, S.4
-
34
-
-
0032030656
-
Integrins and GTPases in tumour cell growth, motilily and invasion
-
Keely, P., L. Parise, and R. Juliano. 1998. Integrins and GTPases in tumour cell growth, motilily and invasion. Trends Cell Biol. 8:101-106.
-
(1998)
Trends Cell Biol.
, vol.8
, pp. 101-106
-
-
Keely, P.1
Parise, L.2
Juliano, R.3
-
35
-
-
0031459917
-
Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K
-
Keely, P.J., J.K. Westwick, I.P. Whitehead, C.J. Der, and L.V. Parise. 1997. Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K. Nature. 390:632-636.
-
(1997)
Nature
, vol.390
, pp. 632-636
-
-
Keely, P.J.1
Westwick, J.K.2
Whitehead, I.P.3
Der, C.J.4
Parise, L.V.5
-
36
-
-
0032563207
-
Phosphoinositide 3-kinase induces scattering and tubulogenesis in epithelial cells through a novel pathway
-
Khwaja, A., K. Lehmann, B.M. Marte, and J. Downward. 1998. Phosphoinositide 3-kinase induces scattering and tubulogenesis in epithelial cells through a novel pathway. J. Biol. Chem. 273:18793-18801.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 18793-18801
-
-
Khwaja, A.1
Lehmann, K.2
Marte, B.M.3
Downward, J.4
-
37
-
-
0029116143
-
Tyrosine phosphorylation regulates the adhesions of Ras-transformed breast epithelia
-
Kinch, M.S., G.J. Clark, C.J. Der, and K. Burridge. 1995. Tyrosine phosphorylation regulates the adhesions of Ras-transformed breast epithelia. J. Cell Biol. 130:461-471.
-
(1995)
J. Cell Biol.
, vol.130
, pp. 461-471
-
-
Kinch, M.S.1
Clark, G.J.2
Der, C.J.3
Burridge, K.4
-
38
-
-
0030931217
-
Regulation of cell motility by mitogen-activated protein kinase
-
Klemke, R., S. Cai, A. Giannini, P. Gallagher, P. de Lanerolle, and D. Cheresh. 1997. Regulation of cell motility by mitogen-activated protein kinase. J. Cell Biol. 137:481-492.
-
(1997)
J. Cell Biol.
, vol.137
, pp. 481-492
-
-
Klemke, R.1
Cai, S.2
Giannini, A.3
Gallagher, P.4
De Lanerolle, P.5
Cheresh, D.6
-
39
-
-
0029050557
-
Phosphoinositide 3-kinase inhibition spares actin assembly in activating platelets but reverses platelet aggregation
-
Kovacsovics, T.J., C. Bachelot, A. Toker, C.J. Vlahos, B. Duckworth, L.C. Cantley, and J.H. Hartwig. 1995. Phosphoinositide 3-kinase inhibition spares actin assembly in activating platelets but reverses platelet aggregation. J. Biol. Chem. 270:11358-11366.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 11358-11366
-
-
Kovacsovics, T.J.1
Bachelot, C.2
Toker, A.3
Vlahos, C.J.4
Duckworth, B.5
Cantley, L.C.6
Hartwig, J.H.7
-
40
-
-
0028055272
-
Regulation of chemotaxis by the platelet-derived growth factor receptor-β
-
Kundra, V., J.A. Escobedo, A. Kaziauskas, H.K. Kim, S.G. Rhee, L.T. Williams, and B.R. Zetter. 1994. Regulation of chemotaxis by the platelet-derived growth factor receptor-β. Nature. 367:474-476.
-
(1994)
Nature
, vol.367
, pp. 474-476
-
-
Kundra, V.1
Escobedo, J.A.2
Kaziauskas, A.3
Kim, H.K.4
Rhee, S.G.5
Williams, L.T.6
Zetter, B.R.7
-
41
-
-
0027994108
-
Single subunit chimeric integrins as mimics and inhibitors of endogenous integrin functions in receptor localization, cell spreading and migration, and matrix assembly
-
LaFlamme, S.E., L.A. Thomas, S.S. Yamada, and KM Yamada. 1994. Single subunit chimeric integrins as mimics and inhibitors of endogenous integrin functions in receptor localization, cell spreading and migration, and matrix assembly. J. Cell Biol. 126:1287-1298.
-
(1994)
J. Cell Biol.
, vol.126
, pp. 1287-1298
-
-
LaFlamme, S.E.1
Thomas, L.A.2
Yamada, S.S.3
Yamada, K.M.4
-
42
-
-
0030059222
-
Role of Rho in chemoattractant-activated leukocyte adhesion through integrins
-
Laudanna, C., J.J. Campbell, and E.C. Butcher. 1996. Role of Rho in chemoattractant-activated leukocyte adhesion through integrins. Science. 271:981-983.
-
(1996)
Science
, vol.271
, pp. 981-983
-
-
Laudanna, C.1
Campbell, J.J.2
Butcher, E.C.3
-
43
-
-
0029759727
-
Protein kinase C regulates αvβ5-dependent cytoskeletal associations and focal adhesion kinase phosphorylation
-
Lewis, J.M., D.A. Cheresh, and M.A. Schwartz. 1996. Protein kinase C regulates αvβ5-dependent cytoskeletal associations and focal adhesion kinase phosphorylation. J. Cell Biol. 134:1323-1332.
-
(1996)
J. Cell Biol.
, vol.134
, pp. 1323-1332
-
-
Lewis, J.M.1
Cheresh, D.A.2
Schwartz, M.A.3
-
44
-
-
0031003237
-
Cell anchorage permits efficient signal transduction between ras and its downstream kinase
-
Lin, T.H., Q. Chen, A. Howe, and R.L. Juliano. 1997. Cell anchorage permits efficient signal transduction between ras and its downstream kinase. J. Biol. Chem. 272:8849-8852.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 8849-8852
-
-
Lin, T.H.1
Chen, Q.2
Howe, A.3
Juliano, R.L.4
-
45
-
-
0023390847
-
Heterologous expression and characterization of the human R-ras gene product
-
Lowe, D.G., and D.V. Goeddel. 1987. Heterologous expression and characterization of the human R-ras gene product. Mol. Cell. Biol. 7:2845-2856.
-
(1987)
Mol. Cell. Biol.
, vol.7
, pp. 2845-2856
-
-
Lowe, D.G.1
Goeddel, D.V.2
-
46
-
-
0023657439
-
Structure of the human and murine R-ras genes, novel genes closely related to ras proto-oncogenes
-
Lowe, D.G., D.J. Capon, E. Delwart, A.Y. Sakaguchi, S.L. Naylor, and D.V. Goeddel. 1987. Structure of the human and murine R-ras genes, novel genes closely related to ras proto-oncogenes. Cell. 48:137-146.
-
(1987)
Cell
, vol.48
, pp. 137-146
-
-
Lowe, D.G.1
Capon, D.J.2
Delwart, E.3
Sakaguchi, A.Y.4
Naylor, S.L.5
Goeddel, D.V.6
-
47
-
-
0028238346
-
Disruption of integrin function and induction of tyrosine phosphorylalion by the autonomously expressed β1 integrin cytoplasmic domain
-
Lukashev, M.E., D. Sheppard, and R. Pytela. 1994. Disruption of integrin function and induction of tyrosine phosphorylalion by the autonomously expressed β1 integrin cytoplasmic domain. J. Biol. Chem. 269:18311-18314.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 18311-18314
-
-
Lukashev, M.E.1
Sheppard, D.2
Pytela, R.3
-
48
-
-
0031038131
-
R-Ras can activate the phosphoinositide 3-kinase but not the MAP kinase arm of the Ras effector pathways
-
Marte, B.M., P. Rodriguez-Viciana, S. Wennstrom, P.H. Warne, and J. Downward. 1996. R-Ras can activate the phosphoinositide 3-kinase but not the MAP kinase arm of the Ras effector pathways. Curr. Biol. 7:63-70.
-
(1996)
Curr. Biol.
, vol.7
, pp. 63-70
-
-
Marte, B.M.1
Rodriguez-Viciana, P.2
Wennstrom, S.3
Warne, P.H.4
Downward, J.5
-
49
-
-
0022650891
-
Human fibronectin contains distinct adhesion-and motility-promoting domains for metastatic melanoma cells
-
McCarthy, J.B., S.T. Hagen, and L.T. Furcht. 1986. Human fibronectin contains distinct adhesion-and motility-promoting domains for metastatic melanoma cells. J. Cell Biol. 102:179-188.
-
(1986)
J. Cell Biol.
, vol.102
, pp. 179-188
-
-
McCarthy, J.B.1
Hagen, S.T.2
Furcht, L.T.3
-
50
-
-
0030453194
-
Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: Roles of integrin aggregation and occupancy of receptors
-
Miyamoto, S., H. Teramoto, J.S. Gutkind, and K.M. Yamada. 1996. Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: roles of integrin aggregation and occupancy of receptors. J. Cell Biol. 135:1633-1642.
-
(1996)
J. Cell Biol.
, vol.135
, pp. 1633-1642
-
-
Miyamoto, S.1
Teramoto, H.2
Gutkind, J.S.3
Yamada, K.M.4
-
51
-
-
0028855838
-
Matrix/integrin interaction activates the mitogen-activated protein kinase, p44erk-1 and p42erk-2
-
Morino, N., T. Mimura, K. Hamasaki, K. Tobe, K. Ueki, K. Kikuchi, K. Takehara, T. Kadowaki, Y. Yazaki, and Y. Nojima. 1995. Matrix/integrin interaction activates the mitogen-activated protein kinase, p44erk-1 and p42erk-2. J. Biol. Chem. 270:269-273.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 269-273
-
-
Morino, N.1
Mimura, T.2
Hamasaki, K.3
Tobe, K.4
Ueki, K.5
Kikuchi, K.6
Takehara, K.7
Kadowaki, T.8
Yazaki, Y.9
Nojima, Y.10
-
52
-
-
0028961293
-
Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
-
Nobes, C.D., and A. Hall. 1995. Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. Cell. 81:53-62.
-
(1995)
Cell
, vol.81
, pp. 53-62
-
-
Nobes, C.D.1
Hall, A.2
-
53
-
-
0028066897
-
Ligand binding to monocyte α5β1 integrin activates the α2β1 receptor via the α5 subunit cytoplasmic domain and protein kinase C
-
Pacifici, R., J. Roman, R. Kimble, R. Civitelli, CM. Brownfield, and C. Bizzarri. 1994. Ligand binding to monocyte α5β1 integrin activates the α2β1 receptor via the α5 subunit cytoplasmic domain and protein kinase C. J. Immunol. 153:2222-2233.
-
(1994)
J. Immunol.
, vol.153
, pp. 2222-2233
-
-
Pacifici, R.1
Roman, J.2
Kimble, R.3
Civitelli, R.4
Brownfield, C.M.5
Bizzarri, C.6
-
54
-
-
0031034352
-
Integrin-ligand binding properties govern cell migration speed through cell-substratum adhesiveness
-
Palecek, S.P., J.C. Loftus, M.H. Ginsberg, D.A. Lauffenburger, and A.F. Horwitz. 1997. Integrin-ligand binding properties govern cell migration speed through cell-substratum adhesiveness. Nature. 385:537-540.
-
(1997)
Nature
, vol.385
, pp. 537-540
-
-
Palecek, S.P.1
Loftus, J.C.2
Ginsberg, M.H.3
Lauffenburger, D.A.4
Horwitz, A.F.5
-
55
-
-
0029828456
-
Involvement of the small GTPase Rho in integrin-mediated activation of mitogen-activated protein kinase
-
Renshaw, M.W., D. Toksoz, and M.A. Schwartz. 1996. Involvement of the small GTPase Rho in integrin-mediated activation of mitogen-activated protein kinase. J. Biol. Chem. 271:21691-21694.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 21691-21694
-
-
Renshaw, M.W.1
Toksoz, D.2
Schwartz, M.A.3
-
57
-
-
0028144704
-
R-ras interacts with rasGAP, neurofibromin, and c-raf but does not regulate cell growth or differentiation
-
Rey, I., P. Taylor-Harris, H. van Erp, and A. Hall. 1994. R-ras interacts with rasGAP, neurofibromin, and c-raf but does not regulate cell growth or differentiation. Oncogene. 9:685-692.
-
(1994)
Oncogene
, vol.9
, pp. 685-692
-
-
Rey, I.1
Taylor-Harris, P.2
Van Erp, H.3
Hall, A.4
-
58
-
-
0028074316
-
Phosphatidylinositol-3-OH kinase as a direct target of Ras
-
Rodriguez-Viciana, P., P.H. Warne, R. Dhand, B. Vanhaesebroeck, I. Gout, M.J. Fry, M.D. Waterfield, and J. Downward. 1994. Phosphatidylinositol-3-OH kinase as a direct target of Ras. Nature. 370:527-532.
-
(1994)
Nature
, vol.370
, pp. 527-532
-
-
Rodriguez-Viciana, P.1
Warne, P.H.2
Dhand, R.3
Vanhaesebroeck, B.4
Gout, I.5
Fry, M.J.6
Waterfield, M.D.7
Downward, J.8
-
59
-
-
0030911052
-
Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras
-
Rodriguez-Viciana, P., P.H. Warne, A. Khwaja, B.M. Marte, D. Pappin. P. Das, M.D. Waterfield, A. Ridley, and J. Downward. 1997. Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras. Cell. 89:457-467.
-
(1997)
Cell
, vol.89
, pp. 457-467
-
-
Rodriguez-Viciana, P.1
Warne, P.H.2
Khwaja, A.3
Marte, B.M.4
Pappin, D.5
Das, P.6
Waterfield, M.D.7
Ridley, A.8
Downward, J.9
-
60
-
-
0345252018
-
Activation of the Raf/ MAP kinase cascade by the Ras-related protein TC21 is required for the TC21-mediated transformation of NIH 3T3 cells
-
Rosario, M., H.F. Paterson, and C.J. Marshall. 1999. Activation of the Raf/ MAP kinase cascade by the Ras-related protein TC21 is required for the TC21-mediated transformation of NIH 3T3 cells. EMBO (Eur. Mol. Biol. Organ.) J. 18:1270-1279.
-
(1999)
EMBO (Eur. Mol. Biol. Organ.) J.
, vol.18
, pp. 1270-1279
-
-
Rosario, M.1
Paterson, H.F.2
Marshall, C.J.3
-
61
-
-
0028136185
-
Oncogenic activation of human R-ras by point mutations analogous to those of prototype H-ras oncogenes
-
Saez, R., A.M. Chan, T. Miki, and S.A. Aaronson. 1994. Oncogenic activation of human R-ras by point mutations analogous to those of prototype H-ras oncogenes. Oncogene. 9:2977-2982.
-
(1994)
Oncogene
, vol.9
, pp. 2977-2982
-
-
Saez, R.1
Chan, A.M.2
Miki, T.3
Aaronson, S.A.4
-
62
-
-
0028945545
-
Analysis of collagen receptors
-
Santoro, S.A., M.M. Zutter, J.E. Wu, W.D. Staatz, E.U. Saelman, and P.J. Keely, 1994. Analysis of collagen receptors. Methods Enzymol. 245:147-183.
-
(1994)
Methods Enzymol.
, vol.245
, pp. 147-183
-
-
Santoro, S.A.1
Zutter, M.M.2
Wu, J.E.3
Staatz, W.D.4
Saelman, E.U.5
Keely, P.J.6
-
63
-
-
0029664439
-
Inlegrin α subunit ratios, cytoplasmic domains, and growth factor synergy regulate muscle proliferation and differentiation
-
Sastry, S.K., M. Lakonishok, D.A. Thomas, J. Muschler, and A.F. Horwitz. 1996. Inlegrin α subunit ratios, cytoplasmic domains, and growth factor synergy regulate muscle proliferation and differentiation. J. Cell Biol. 133:169-184.
-
(1996)
J. Cell Biol.
, vol.133
, pp. 169-184
-
-
Sastry, S.K.1
Lakonishok, M.2
Thomas, D.A.3
Muschler, J.4
Horwitz, A.F.5
-
64
-
-
0028609382
-
Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase
-
Schlaepfer, D.D., S.K. Hanks, T. Hunter, and P. van der Geer. 1994. Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase. Nature. 372:786-791.
-
(1994)
Nature
, vol.372
, pp. 786-791
-
-
Schlaepfer, D.D.1
Hanks, S.K.2
Hunter, T.3
Van Der Geer, P.4
-
66
-
-
0029827248
-
Transformation by Rho exchange factor oncogenes is mediated by activation of an integrin-dependent pathway
-
Schwartz, M., D. Toksoz, and R. Khosravi-Far. 1996. Transformation by Rho exchange factor oncogenes is mediated by activation of an integrin-dependent pathway. EMBO (Eur. Mol. Biol. Organ.) J. 15:6525-6530.
-
(1996)
EMBO (Eur. Mol. Biol. Organ.) J.
, vol.15
, pp. 6525-6530
-
-
Schwartz, M.1
Toksoz, D.2
Khosravi-Far, R.3
-
67
-
-
0031456065
-
Activation of phosphoinositide 3-OH kinase by the α6β34 integrin promotes carcinoma invasion
-
Shaw, L.M., I. Rabinovitz, H.H.F. Wang, A. Toker, and A.M. Mercurio. 1997. Activation of phosphoinositide 3-OH kinase by the α6β34 integrin promotes carcinoma invasion. Cell. 91:949-960.
-
(1997)
Cell
, vol.91
, pp. 949-960
-
-
Shaw, L.M.1
Rabinovitz, I.2
Wang, H.H.F.3
Toker, A.4
Mercurio, A.M.5
-
68
-
-
0029583193
-
A role for phosphatidylinositol 3-kinase in the regulation of β1 integrin activity by the CD2 antigen
-
Shimizu, Y., J.L. Mobley, L.D. Finkelstein, and A.S.H. Chan. 1995. A role for phosphatidylinositol 3-kinase in the regulation of β1 integrin activity by the CD2 antigen. J. Cell Biol. 131:1867-1880.
-
(1995)
J. Cell Biol.
, vol.131
, pp. 1867-1880
-
-
Shimizu, Y.1
Mobley, J.L.2
Finkelstein, L.D.3
Chan, A.S.H.4
-
69
-
-
0031036735
-
Ras activation in platelets after stimulation of the thrombin receptor, thromboxane A2 receptor or protein kinase C
-
Shock, D., K. He, J. Wencel-Drake, and L. Parise. 1997. Ras activation in platelets after stimulation of the thrombin receptor, thromboxane A2 receptor or protein kinase C. Biochem. J. 321:525-530.
-
(1997)
Biochem. J.
, vol.321
, pp. 525-530
-
-
Shock, D.1
He, K.2
Wencel-Drake, J.3
Parise, L.4
-
70
-
-
0028577298
-
Identification of the guanine nucleotide dissociation stimulator for Ra1 as a putative effector molecule of R-ras. H-ras, K-ras, and Rap
-
Spaargaren, M., and J.R. Bischoff. 1994. Identification of the guanine nucleotide dissociation stimulator for Ra1 as a putative effector molecule of R-ras. H-ras, K-ras, and Rap. Proc. Natl. Acad. Sci. USA. 91:12609-12613.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 12609-12613
-
-
Spaargaren, M.1
Bischoff, J.R.2
-
71
-
-
0028175939
-
The Ras-related protein R-ras interacts directly with Raf-1 in a GTP-dependent manner
-
Spaargaren, M., G.A. Martin, F. McCormick, M.J. Fernandez-Sarabia, and J.R. Bischoff. 1994. The Ras-related protein R-ras interacts directly with Raf-1 in a GTP-dependent manner. Biochem. J. 300:303-307.
-
(1994)
Biochem. J.
, vol.300
, pp. 303-307
-
-
Spaargaren, M.1
Martin, G.A.2
McCormick, F.3
Fernandez-Sarabia, M.J.4
Bischoff, J.R.5
-
72
-
-
0028560447
-
Activation of protein kinase C family members by the novel polyphosphoinositides PtdIns-3,4-P2 and PtdIns-3,4,5-P3
-
Toker, A., M. Meyer, K.K. Reddy, J.R. Falck, R. Aneja, S. Aneja, A. Parra, D.J. Burns, L.M. Ballas, and L.C. Cantley. 1994. Activation of protein kinase C family members by the novel polyphosphoinositides PtdIns-3,4-P2 and PtdIns-3,4,5-P3. J. Biol. Chem. 269:32358-32367.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 32358-32367
-
-
Toker, A.1
Meyer, M.2
Reddy, K.K.3
Falck, J.R.4
Aneja, R.5
Aneja, S.6
Parra, A.7
Burns, D.J.8
Ballas, L.M.9
Cantley, L.C.10
-
73
-
-
0029023942
-
Rho family GTPases bind to phosphoinositide kinases
-
Tolias, K.F., L.C. Cantley, and C.L. Carpenter. 1995. Rho family GTPases bind to phosphoinositide kinases. J. Biol. Chem. 270:17656-17659.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 17656-17659
-
-
Tolias, K.F.1
Cantley, L.C.2
Carpenter, C.L.3
-
74
-
-
17544377292
-
ADP-ribosylation of the G protein Rho inhibits integrin regulation of tumor cell growth
-
Udagawa, T., and B.W. McIntyre. 1996. ADP-ribosylation of the G protein Rho inhibits integrin regulation of tumor cell growth. J. Biol. Chem. 271: 12542-12548.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 12542-12548
-
-
Udagawa, T.1
McIntyre, B.W.2
-
75
-
-
0027250250
-
Mammalian Ras interacts directly with the serine/threonine kinase Raf
-
Vojlek, A.B., S.M. Hollenberg, and J.A. Cooper. 1993. Mammalian Ras interacts directly with the serine/threonine kinase Raf. Cell. 74:205-214.
-
(1993)
Cell
, vol.74
, pp. 205-214
-
-
Vojlek, A.B.1
Hollenberg, S.M.2
Cooper, J.A.3
-
76
-
-
0027373782
-
Activation of protein kinase C precedes α5β1 integrin-mediated cell spreading on fibronectin
-
Vuori, K., and E. Ruoslahti. 1993. Activation of protein kinase C precedes α5β1 integrin-mediated cell spreading on fibronectin. J. Biol. Chem. 268: 21459-21462.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 21459-21462
-
-
Vuori, K.1
Ruoslahti, E.2
-
77
-
-
0030584077
-
The adaptor protein Shc couples a class of integrins to the control of cell cycle progression
-
Wary, K.K., F. Mainiero, S.J. Isakoff, E.E. Marcantonio, and F.G. Giancotti. 1996. The adaptor protein Shc couples a class of integrins to the control of cell cycle progression. Cell. 87:733-743.
-
(1996)
Cell
, vol.87
, pp. 733-743
-
-
Wary, K.K.1
Mainiero, F.2
Isakoff, S.J.3
Marcantonio, E.E.4
Giancotti, F.G.5
-
78
-
-
0032489532
-
Regulation of mitogen-activated protein kinase activation by the cytoplasmic domain of the α6 integrin subunit
-
Wei, J., L.M. Shaw, and A.M. Mercurio. 1998. Regulation of mitogen-activated protein kinase activation by the cytoplasmic domain of the α6 integrin subunit. J. Biol. Chem. 273:5903-5907.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 5903-5907
-
-
Wei, J.1
Shaw, L.M.2
Mercurio, A.M.3
-
79
-
-
0029164237
-
Integrin transmembrane signaling and cytoskeletal control
-
Yamada, K.M., and S. Miyamoto. 1995. Integrin transmembrane signaling and cytoskeletal control. Curr. Opin. Cell Biol. 7:681-689.
-
(1995)
Curr. Opin. Cell Biol.
, vol.7
, pp. 681-689
-
-
Yamada, K.M.1
Miyamoto, S.2
-
80
-
-
0031660652
-
Highly stoichiometric, stable, and specific association of integrin α3β1 with CD151 provides a major link to phosphatidylinositol 4-kinase, and may regulate cell migration
-
Yauch, R.L., F. Berditchevski, M.B. Harler, J. Reichner, and M.E. Hemler. 1998. Highly stoichiometric, stable, and specific association of integrin α3β1 with CD151 provides a major link to phosphatidylinositol 4-kinase, and may regulate cell migration. Mol. Biol. Cell. 9:2751-2765.
-
(1998)
Mol. Biol. Cell
, vol.9
, pp. 2751-2765
-
-
Yauch, R.L.1
Berditchevski, F.2
Harler, M.B.3
Reichner, J.4
Hemler, M.E.5
-
81
-
-
0029870339
-
Integrin activation by R-ras
-
Zhang, Z., K. Vuori, H.G. Wang, J.C. Reed, and E. Ruoslahti. 1996. Integrin activation by R-ras. Cell. 85:61-69.
-
(1996)
Cell
, vol.85
, pp. 61-69
-
-
Zhang, Z.1
Vuori, K.2
Wang, H.G.3
Reed, J.C.4
Ruoslahti, E.5
-
82
-
-
0028338545
-
Activation of phosphoinositide 3-kinase activity by Cdc42Hs binding to p85
-
Zheng, Y., S. Bagrodia, and R.A. Cerione. 1994. Activation of phosphoinositide 3-kinase activity by Cdc42Hs binding to p85. J. Biol. Chem. 269:18727-18730.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 18727-18730
-
-
Zheng, Y.1
Bagrodia, S.2
Cerione, R.A.3
-
83
-
-
0028904784
-
Integrin-dependent activation of MAP kinase: A link to shape-dependent cell proliferation
-
Zhu, X., and R.K. Assoian. 1995. Integrin-dependent activation of MAP kinase: a link to shape-dependent cell proliferation. Mol. Biol. Cell. 6:273-282.
-
(1995)
Mol. Biol. Cell
, vol.6
, pp. 273-282
-
-
Zhu, X.1
Assoian, R.K.2
-
84
-
-
0025037292
-
Decreased expression of integrin adhesive protein receptors in adenocarcinoma of the breast
-
Zutter, M., G. Mazoujian, and S. Santoro. 1990. Decreased expression of integrin adhesive protein receptors in adenocarcinoma of the breast. Am. J. Pathol. 137:863-870.
-
(1990)
Am. J. Pathol.
, vol.137
, pp. 863-870
-
-
Zutter, M.1
Mazoujian, G.2
Santoro, S.3
-
85
-
-
0028978457
-
Reexpression of the α2β1 integrin abrogates the malignant phenotype of breast carcinoma cells
-
Zutter, M., S. Santoro, W. Staatz, and Y. Tsung. 1995. Reexpression of the α2β1 integrin abrogates the malignant phenotype of breast carcinoma cells. Proc. Natl. Acad. Sci. USA. 92:7411-7415.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 7411-7415
-
-
Zutter, M.1
Santoro, S.2
Staatz, W.3
Tsung, Y.4
|