Lessons and conclusions from dissecting the mechanism of a bisubstrate enzyme: Thymidylate synthase mutagenesis, function, and structure

Biochemistry

Volumn 42, Issue 2, 2003, Pages 248-256

  Finer Moore, Janet S ^a   Santi, Daniel V ^a   Stroud, Robert M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

THYMIDINE PHOSPHATE; THYMIDYLATE SYNTHASE;

AMINO ACID SEQUENCE; ARTICLE; CATALYSIS; ENZYME MECHANISM; ENZYME SUBSTRATE COMPLEX; HUMAN; LACTOBACILLUS CASEI; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

BINDING SITES; CATALYSIS; KINETICS; LACTOBACILLUS CASEI; MODELS, CHEMICAL; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; SUBSTRATE SPECIFICITY; THYMIDYLATE SYNTHASE;

LACTOBACILLUS CASEI;

EID: 0037457980     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi020599a     Document Type: Article

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