Replacement set mutagenesis of the four phosphate-binding arginine residues of thymidylate synthase

Protein Engineering

Volumn 13, Issue 8, 2000, Pages 557-563

  Kawase, Shido ^a   Cho, Sung Woo ^b   Rozelle, James ^a   Stroud, Robert M ^a   Finer Moore, Janet ^a   Santi, Daniel V ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b University of Ulsan College of Medicine   (South Korea)

Author keywords

dUMP; Electrostatic; Hydrogen bond; Saturation mutagenesis

Indexed keywords

BACTERIAL ENZYME; MUTANT PROTEIN; THYMIDYLATE SYNTHASE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; ENZYME ANALYSIS; ENZYME BINDING; ENZYME KINETICS; LACTOBACILLUS CASEI; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL;

BACTERIA (MICROORGANISMS); FELIS CATUS; LACTOBACILLUS CASEI;

EID: 0033825052     PISSN: 02692139     EISSN: None     Source Type: Journal    
DOI: 10.1093/protein/13.8.557     Document Type: Article

References (24)