Aspartate 221 of thymidylate synthase is involved in folate cofactor binding and in catalysis

Biochemistry

Volumn 37, Issue 25, 1998, Pages 9038-9042

  Chiericatti, Giuseppe ^a   Santi, Daniel V ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; BACTERIAL ENZYME; CYSTEINE; DEOXYURIDINE PHOSPHATE; FOLIC ACID; THYMIDYLATE SYNTHASE;

ARTICLE; BINDING AFFINITY; CATALYSIS; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME BINDING; ENZYME STRUCTURE; HYDROGEN BOND; LACTOBACILLUS CASEI; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL;

ASPARTIC ACID; BINDING SITES; CATALYSIS; COENZYMES; DEOXYURACIL NUCLEOTIDES; ESCHERICHIA COLI; FLUORODEOXYURIDYLATE; GENETIC COMPLEMENTATION TEST; HALOGENS; KINETICS; LACTOBACILLUS CASEI; MUTAGENESIS, INSERTIONAL; TETRAHYDROFOLATES; THYMIDINE MONOPHOSPHATE; THYMIDYLATE SYNTHASE;

BACTERIA (MICROORGANISMS); LACTOBACILLUS CASEI;

EID: 0032560624     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9802770     Document Type: Article

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