Inhibition of the α-ketoglutarate dehydrogenase complex alters mitochondrial function and cellular calcium regulation

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1637, Issue 1, 2003, Pages 119-126

  Huang, Hsueh Meei ^a   Zhang, Hui ^a   Xu, Hui ^a   Gibson, Gary E ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Calcium; Cytochrome c; Endoplasmic reticulum; Mitochondrial membrane potential; Neuroblastoma; keto methyl n valeric acid

Indexed keywords

ALPHA KETO BETA METHYL N VALERIC ACID; BRADYKININ; CALCIUM; CALCIUM ION; CYTOCHROME C; MITOCHONDRIAL ENZYME; OXOGLUTARATE DEHYDROGENASE; UNCLASSIFIED DRUG; VALERIC ACID DERIVATIVE;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CALCIUM HOMEOSTASIS; CALCIUM METABOLISM; CALCIUM TRANSPORT; CELL DEATH; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSOL; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; ENZYME RELEASE; FIBROBLAST; GENE MUTATION; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL RESPIRATION; NERVE CELL CULTURE; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM;

EID: 0037454668     PISSN: 09254439     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4439(02)00222-3     Document Type: Article

References (84)

1. Schapira A.H. Biochim. Biophys. Acta. 1366:1998;225-233.
2. Beal M.F. Biochim. Biophys. Acta. 1366:1998;211-223.
3. Gibson G.E., Sheu K.F., Blass J.P., Baker A., Carlson K.C., Harding B., Perrino P. Arch. Neurol. 45:1988;836-840.
4. Butterworth R.F., Besnard A.M. Metab. Brain Dis. 1990;179-184.
5. Mastrogiacomo F., Bergeron C., Kish S.J. J. Neurochem. 61:1993;2007-2014.
6. Terwel D., Bothmer J., Wolf E., Meng F., Jolles J. J. Neurol. Sci. 161:1998;47-56.
7. Sheu K.F., Cooper A.J., Koike K., Koike M., Lindsay J.G., Blass J.P. Ann. Neurol. 35:1994;312-318.
8. Jimenez-Jimenez F.J., Molina J.A., Hernanz A., Fernandez-Vivancos E., de Bustos F., Barcenilla B., Gomez-Escalonilla C., Zurdo M., Berbel A., Villanueva C. Neurosci. Lett. 271:1999;33-36.
9. Mizuno Y., Matuda S., Yoshino H., Mori H., Hattori N., Ikebe S. Ann. Neurol. 35:1994;204-210.
10. Mizuno Y., Ikebe S., Hattori N., Nakagawa-Hattori Y., Mochizuki H., Tanaka M., Ozawa T. Biochim. Biophys. Acta. 1271:1995;265-274.
11. G.E. Gibson, A.E. Kingsbury, H. Xu, J.G. Lindsay, S. Daniel, O.J.F. Foster, A.J. Lees, J.P. Blass, Neurochem. Int. (in press).
12. Butterworth R.F., Kril J.J., Harper C.G. Alcohol Clin. Exp. Res. 17:1993;1084-1088.
13. Mastrogiacomo F., LaMarche J., Dozic S., Lindsay G., Bettendorff L., Robi taille Y., Schut L., Kish S.J. Neurodegeneration. 5:1996;27-33.
14. Albers D.S., Augood S.J., Park L.C., Browne S.E., Martin D.M., Adamson J., Hutton M., Standaert D.G., Vonsattel J.P., Gibson G.E., Beal M.F. J. Neurochem. 74:2000;878-881.
15. Park L.C., Albers D.S., Xu H., Lindsay J.G., Beal M.F., Gibson G.E. J. Neurosci. Res. 66:2001;1028-1034.
16. Huang H.M., Martins R., Gandy S., Etcheberrigaray R., Ito E., Alkon D.L., Blass J., Gibson G. Ann. N.Y. Acad. Sci. 747:1994;225-244.
17. Mattson M.P., Guo Q., Furukawa K., Pedersen W.A. J. Neurochem. 70:1998;1-14.
18. Ito E., Oka K., Etcheberrigaray R., Nelson T.J., McPhie D.L., Tofel-Grehl B., Gibson G.E., Alkon D.L. Proc. Natl. Acad. Sci. U. S. A. 91:1994;534-538.
19. Gibson G.E., Vestling M., Zhang H., Szolosi S., Alkon D., Lannfelt L., Gandy S., Cowburn R.F. Neurobiol. Aging. 18:1997;573-580.
20. Budd S.L., Nicholls D.G. J. Neurochem. 67:1996;2282-2291.
21. White R.J., Reynolds I.J. J. Neurosci. 15:1995;1318-1328.
22. Schinder A.F., Olson E.C., Spitzer N.C., Montal M. J. Neurosci. 16:1996;6125-6133.
23. Nicholls D.G., Budd S.L. Physiol. Rev. 80:2000;315-360.
24. Boveris A., Oshino N., Chance B. Biochem. J. 128:1972;617-630.
25. Mitchell P. Science. 206:1979;1148-1159.
26. Azzone G.F., Petronilli V., Zoratti M. Biochem. Soc. Trans. 12:1984;414-416.
27. Loew L.M., Tuft R.A., Carrington W., Fay F.S. Biophys. J. 65:1993;2396-2407.
28. Fink C., Morgan F., Loew L.M. Biophys. J. 75:1998;1648-1658.
29. Scaduto R.C. Jr., Grotyohann L.W. Biophys. J. 76:1999;469-477.
30. Bossy-Wetzel E., Newmeyer D.D., Green D.R. EMBO J. 17:1998;37-49.
31. Bortner C.D., Cidlowski J.A. J. Biol. Chem. 274:1999;21953-21962.
32. Rottenberg H., Wu S. Biochim. Biophys. Acta. 1404:1998;393-404.
33. Zhang H., Huang H.M., Carson R.C., Mahmood J., Thomas H.M., Gibson G.E. Anal. Biochem. 298:2001;170-180.
34. Brookes P.S., Salinas E.P., Darley-Usmar K., Eiserich J.P., Freeman B.A., Darley-Usmar V.M., Anderson P.G. J. Biol. Chem. 275:2000;20474-20479.
35. Araya R., Uehara T., Nomura Y. FEBS Lett. 439:1998;168-172.
36. Cai J., Yang J., Jones D.P. Biochim. Biophys. Acta. 1366:1998;139-149.
37. Fujimura M., Morita-Fujimura Y., Murakami K., Kawase M., Chan P.H. J. Cereb. Blood Flow Metab. 18:1998;1239-1247.
38. Perez-Pinzon M.A., Xu G.P., Born J., Lorenzo J., Busto R., Rosenthal M., Sick T.J. J. Cereb. Blood Flow Metab. 19:1999;39-43.
39. Petronilli V., Penzo D., Scorrano L., Bernardi P., Di Lisa F. J. Biol. Chem. 276:2001;12030-12034.
40. Bernardi P., Petronilli V., Di Lisa F., Forte M. Trends Biochem. Sci. 26:2001;112-117.
41. Grubb D.R., Ly J.D., Vaillant F., Johnson K.L., Lawen A. Oncogene. 20:2001;4085-4094.
42. Waterhouse N.J., Goldstein J.C., von Ahsen O., Schuler M., Newmeyer D.D., Green D.R. J. Cell Biol. 153:2001;319-328.
43. Achenbach T.V., Muller R., Slater E.P. J. Biol. Chem. 275:2000;32089-32097.
44. Kim T.H., Zhao Y., Barber M.J., Kuharsky D.K., Yin X.M. J. Biol. Chem. 275:2000;39474-39481.
45. Eskes R., Antonsson B., Osen-Sand A., Montessuit S., Richter C., Sadoul R., Mazzei G., Nichols A., Martinou J.C. J. Cell Biol. 143:1998;217-224.
46. Nicholls D.G., Akerman K.E. Philos. Trans. R. Soc. Lond., B Biol. Sci. 296:1981;115-122.
47. Scott I.D., Akerman K.E., Nicholls D.G. Biochem. J. 192:1980;873-880.
48. Rutter G.A., Rizzuto R. Trends Biochem. Sci. 25:2000;215-221.
49. Duchen M.R. J. Physiol. 529(Pt 1):2000;57-68.
50. Nicholls D.G., Budd S.L. BioFactors. 8:1998;287-299.
51. Foyouzi-Youssefi R., Arnaudeau S., Borner C., Kelley W.L., Tschopp J., Lew D.P., Demaurex N., Krause K.H. Proc. Natl. Acad. Sci. U. S. A. 97:2000;5723-5728.
52. Pinton P., Ferrari D., Rapizzi E., Di Virgilio F.D., Pozzan T., Rizzuto R. EMBO J. 20:2001;2690-2701.
53. Gibson G.E., Blass J.P. J. Neurochem. 26:1976;1073-1078.
54. Patel M.S. Biochem. J. 144:1974;91-97.
55. Blass J.P., Lewis C.A. Biochem. J. 131:1973;31-37.
56. Park L.C., Calingasan N.Y., Sheu K.F., Gibson G.E. Anal. Biochem. 277:2000;86-93.
57. Yang J., Liu X., Bhalla K., Kim C.N., Ibrado A.M., Cai J., Peng T.I., Jones D.P., Wang X. Science. 275:1997;1129-1132.
58. Tretter L., Adam-Vizi V. J. Neurosci. 20:2000;8972-8979.
59. Cooper A.L., Sheu K.F., Blass J.P. Dev. Neurosci. 18:1996;499-504.
60. Bernardi P., Scorrano L., Colonna R., Petronilli V., Di Lisa F. Eur. J. Biochem. 264:1999;687-701.
61. Amarante-Mendes G.P., Naekyung Kim C., Liu L., Huang Y., Perkins C.L., Green D.R., Bhalla K. Blood. 91:1998;1700-1705.
62. Anuradha C.D., Kanno S., Hirano S. Free Radic. Biol. Med. 31:2001;367-373.
63. Chen Q., Takeyama N., Brady G., Watson A.J., Dive C. Blood. 92:1998;4545-4553.
64. Heiskanen K.M., Bhat M.B., Wang H.W., Ma J., Nieminen A.L. J. Biol. Chem. 274:1999;5654-5658.
65. Kluck R.M., Bossy-Wetzel E., Green D.R., Newmeyer D.D. Science. 275:1997;1132-1136.
66. Susin S.A., Zamzami N., Castedo M., Hirsch T., Marchetti P., Macho A., Daugas E., Geuskens M., Kroemer G. J. Exp. Med. 184:1996;1331-1341.
67. Kristal B.S., Stavrovskaya I.G., Krasnikov B.F., Lukyanova M. Soc. Neurosci. Abstr. 2002;18.9.
68. Gibson G.E., Zhang H., Sheu K.F., Bogdanovich N., Lindsay J.G., Lannfelt L., Vestling M., Cowburn R.F. Ann. Neurol. 44:1998;676-681.
69. Mattson M.P., Guo Q. J. Neurosci. Res. 50:1997;505-513.
70. Paschen W., Frandsen A. J. Neurochem. 79:2001;719-725.
71. Paschen W., Doutheil J. J. Cereb. Blood Flow Metab. 19:1999;1-18.
72. Leissring M.A., Paul B.A., Parker I., Cotman C.W., LaFerla F.M. J. Neurochem. 72:1999;1061-1068.
73. Guo Q., Furukawa K., Sopher B.L., Pham D.G., Xie J., Robinson N., Martin G.M., Mattson M.P. NeuroReport. 8:1996;379-383.
74. Bunik V., Raddatz G., Lemaire S., Meyer Y., Jacquot J.P., Bisswanger H. Protein Sci. 8:1999;65-74.
75. Bryk R., Lima C.D., Erdjument-Bromage H., Tempst P., Nathan C. Science. 295:2002;1073-1077.
76. Chen Y., Cai J., Murphy T.J., Jones D.P. J. Biol. Chem. 277:2002;33242-33248.
77. Costantini P., Belzacq A.S., Vieira H.L., Larochette N., de Pablo M.A., Zamzami N., Susin S.A., Brenner C., Kroemer G. Oncogene. 19:2002;307-314.
78. Vieira H.L., Belzacq A.S., Haouzi D., Bernassola F., Cohen I., Jacotot E., Ferri K.F., El Hamel C., Bartle L.M., Melino G., Brenner C., Goldmacher V., Kroemer G. Oncogene. 20:2001;4305-4316.
79. Bernardi P., Broekemeier K.M., Pfeiffer D.R. J. Bioenerg. Biomembranes. 26:1994;509-517.
80. Biguet C., Wakasugi N., Mishal Z., Holmgren A., Chouaib S., Tursz T., Wakasugi H. J. Biol. Chem. 269:1994;28865-28870.
81. Arnaudeau S., Kelley W.L., Walsh J.V. Jr., Demaurex N. J. Biol. Chem. 276:2001;29430-29439.
82. Kahlert S., Reiser G. J. Neurosci. Res. 61:2000;409-420.
83. Rizzuto R., Pinton P., Carrington W., Fay F.S., Fogarty K.E., Lifshitz L.M., Tuft R.A., Pozzan T. Science. 280:1998;1763-1766.
84. Denton R.M., McCormack J.G. FEBS Lett. 119:1980;1-8.