The VHL protein recruits a novel KRAB-A domain protein to repress HIF-1α transcriptional activity

EMBO Journal

Volumn 22, Issue 8, 2003, Pages 1857-1867

  Li, Zaibo ^a   Wang, Dakun ^a   Na, Xi ^a   Schoen, Susan R ^a   Messing, Edward M ^a   Wu, Guan ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

HIF 1 ; KRAB domain; VHL; VHLaK; ZnF197

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; PROTEIN; UNCLASSIFIED DRUG; VASCULOTROPIN; VHLAK PROTEIN; VON HIPPEL LINDAU PROTEIN;

ALTERNATIVE RNA SPLICING; ANIMAL CELL; ARTICLE; COMPLEX FORMATION; HUMAN; HUMAN CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; TRANSCRIPTION REGULATION; ZINC FINGER MOTIF;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; ANIMALS; CARRIER PROTEINS; CELL LINE; DNA-BINDING PROTEINS; ENDOTHELIAL GROWTH FACTORS; GENE EXPRESSION REGULATION; GENES, TUMOR SUPPRESSOR; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LIGASES; LYMPHOKINES; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; REPRESSOR PROTEINS; RNA, MESSENGER; SEQUENCE ALIGNMENT; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEINS; TWO-HYBRID SYSTEM TECHNIQUES; UBIQUITIN-PROTEIN LIGASES; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS; VON HIPPEL-LINDAU TUMOR SUPPRESSOR PROTEIN;

ANIMALIA;

EID: 0037446951     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdg173     Document Type: Article

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