A possible involvement of TIF1α, and TIF1β in the epigenetic control of transcription by nuclear receptors

EMBO Journal

Volumn 15, Issue 23, 1996, Pages 6701-6715

  Le Douarin, Bertrand ^a   Nielsen, Anders Lade ^a   Garnier, Jean Marie ^a   Ichinose, Hiroshi ^a   Jeanmougin, François ^a   Losson, Régine ^a   Chambon, Pierre ^a  

^a l'alimentation et l'Environnement   (France)

Author keywords

Activation function AF 2; Chromatin; HP1; SNF2 ; Transcriptional mediators

Indexed keywords

BINDING PROTEIN; CELL NUCLEUS RECEPTOR; DNA BINDING PROTEIN; SYNAPSIN I; TRANSCRIPTION FACTOR;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; CELL DIFFERENTIATION; CHROMATIN STRUCTURE; CONTROLLED STUDY; DNA SEQUENCE; DROSOPHILA; HOMEOSTASIS; LIGAND BINDING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN STRUCTURE; TRANSACTIVATION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

EID: 0029841744     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1996.tb01060.x     Document Type: Article

References (95)

1. Aasland, R. and Stewart, A.F. (1995) The chromo shadow domain, a second chromo domain in heterochromatin-binding protein 1, HP1. Nucleic Acids Res., 23, 3163-3173.
2. Aasland, R., Gibson, T.J. and Stewart, A.F. (1995) The PHD finger: implications for chromatin-mediated transcriptional regulation. Trends Biochem. Sci., 20, 56-59.
3. Ali, S., Lutz, Y., Bellocq, J.P., Chenard-Neu, M.P., Rouyer, N. and Metzger, D. (1993) Production and characterization of monoclonal antibodies recognising defined regions of the human oestrogen receptor. Hybridoma, 12, 391-405.
4. Altschul, S.F., Gish, W., Miller, W., Myers, E.W. and Lipman, D.J. (1990) Basic local alignment search tool. J. Mol. Biol., 215, 403-410.
5. Barettino, D., Vivanco-Ruiz, M.M. and Stunnenberg, H.G. (1994) Characterization of the ligand-dependent transactivation domain of thyroid hormone receptor. EMBO J., 13, 3039-3049.
6. Beato, M., Herrlich, P. and Schütz, G. (1995) Steroid hormone receptors: many actors in search of a plot. Cell, 83, 851-857.
7. Bellefroid, E.J., Poncelet, D.A., Lecocq, P.J., Revelant, O. and Martial, J.A. (1991) The evolutionarily conserved Krüppel-associated box domain defines a subfamily of eukaryotic multifingered proteins. Proc. Natl Acad. Sci. USA, 88, 3608-3612.
8. Bellefroid, E.J. et al. (1995) Emergence of the ZNF91 Krüppel-associated box-containing zinc finger gene family in the last common ancestor of anthropoidea. Proc Natl Acad. Sci. USA, 92, 10757-10761.
9. Bellini, M., Lacroix, J.C. and Gall, J.G. (1993) A putative zinc-binding protein on lampbrush chromosome loops. EMBO J., 12, 107-114.
10. Bourguet, W., Ruff, M., Chambon, P., Gronemeyer, H.G. and Moras, D. (1995) Crystal structure of the ligand binding domain of the human nuclear receptor RXRα. Nature, 375, 377-382.
11. Brownell, J.E., Zhou, J., Ranalli, T., Kobayashi, R., Edmondson, D.G., Roth, S.Y. and Allis, C.D. (1996) Tetrahymena histone acetyltransferase A: a homology to yeast Gcn5p linking histone acetylation to gene activation. Cell, 84, 843-851.
12. Bunker, C.A. and Kingston, R.E. (1994) Transcriptional repression by Drosophila and mammalian Polycomb group proteins in transfected mammalian cells. Mol. Cell. Biol., 14, 1721-1732.
13. Cavaillès, V., Dauvois, S., L'Horset, F., Lopez, G., Hoare, S., Kushner, P.J. and Parker, M.G. (1995) Nuclear factor RIP140 modulates transcriptional activation by the estrogen receptor. EMBO J., 14, 3741-3751.
14. Cerf, C., Lippens, G., Muyldermans, S., Segers, A., Ramakrishnan, V., Wodak, S.J., Hallenga, K. and Wyns, L. (1993) Homo- and heteronuclear two-dimensional NMR studies of the globular domain of histone H1: sequential assignment and secondary strutures. Biochemistry, 32, 11345-11351.
15. Chambon, P. (1996) A decade of molecular biology of retinoic acid receptors. FASEB J., 10, 940-954.
16. Chiba, H., Muramatsu, M., Nomoto, A. and Kato, H. (1994) Two human homologues of Saccharomyces cerevisiae SWI2/SNF2 and Drosophila brahma are transcriptional coactivators cooperating with the estrogen receptor and the retinoic acid receptor. Nucleic Acids Res., 22, 1815-1820.
17. Clark, R.F. and Elgin, S.C.R. (1992) Heterochromatin protein 1, a known suppressor of position-effect variegation, is highly conserved in Drosophila. Nucleic Acids Res., 20, 6067-6074.
18. Cuypers, H.T., van Loon-Klaassen, L.A., Egberts, W.T., de Jong, W.W. and Bloemendal, H. (1992) The primary structure of leucine aminopeptidase from bovine eye lens. J. Biol. Chem., 257, 7077-7085.
19. Danielian, P.S., White, R., Lees, J.A. and Parker, M.G. (1992) Identification of a conserved region required for hormone dependent transcriptional activation by steroid hormone receptors. EMBO J., 11, 1025-1033.
20. Deutsche, U., Meyer, W. and Thiesen, H.J. (1995) Tetracycline-reversible silencing of eukaryotic promoters. Mol. Cell. Biol., 15, 1907-1914.
21. II250 is a bipartite protein kinase that phosphorylates the basal transcription factor RAP74. Cell, 84, 781-790.
22. Durand, B., Saunders, M., Gaudon, C., Roy, B., Losson, R. and Chambon, P. (1994) Activation function 2 (AF-2) of RAR and RXR: presence of a conserved autonomous constitutive activating domain and influence of the nature of the response element on AF-2 activity. EMBO J., 13, 5370-5382.
23. Eissenberg, J.C., Elgin, S.C.R. and Paro, R. (1995) Epigenetic regulation in Drosophila: a conspiracy of silence. In Elgin, S.C.R. (ed.), Chromatin Structure and Gene Expression. Frontiers in Molecular Biology. Oxford University Press, Oxford, UK, pp. 147-171.
24. Elgin, S.R.C. (1996) Heterochromatin and gene regulation in Drosophila. Curr. Opin. Genet. Dev. 6, 193-202.
25. Fields, S. and Sternglanz, R. (1994) The two-hybrid system: an assay for protein-protein interactions. Trends Genet., 10, 286-292.
26. Freemont, P.S. (1993) The RING finger. A novel protein sequence motif related to the zinc finger. Ann. N.Y. Acad. Sci., 684, 174-192.
27. Geourjon, C. and Delage, G. (1994) SOPM: a self-optimized method for protein secondary structure prediction. Protein Engng, 7, 157-164.
28. Giguère, V. (1994) Retinoic acid receptors and cellular retinoid binding proteins: complex interplay in retinoid signaling. Endocr. Rev., 15, 61-79.
29. Glass, C.K. (1994) Differential recognition of target genes by nuclear receptor monomers, dimers, and heterodimers. Endocr. Rev., 15, 391-407.
30. Goytisolo, F.M., Gerchman, S.-E., Yu, X., Rees, C., Graziano, V., Ramakrishnan, V. and Thomas, J.O. (1996) Identification of two DNA-binding sites on the globular domain of histone H5. EMBO J., 15, 3421-3429.
31. Green, S., Issemann, I. and Scheer, E. (1988) A versatile in vivo and in vitro eukaryotic expression vector for protein engineering. Nucleic Acids Res., 16, 369.
32. Gronemeyer, H. and Laudet, V. (1995) Transcription Factors 3: Nuclear Receptors. Protein Profile Volume 2. Academic Press.
33. Gu, Y., Nakamura, T., Alder, H., Prasad, R., Canaani, O., Cimino, G., Croce, C.M. and Canaani, E. (1992) The t(4; 11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene. Cell, 71, 701-708.
34. Guarente, L. (1995) Transcriptional coactivators in yeast and beyond. Trends Biochem. Sci., 20, 517-521.
35. Halachmi, S., Marden, E., Martin, G., MacKay, H., Abbondanza, C. and Brown, M. (1994) Oestrogen receptor-associated proteins: possible mediators of hormone-induced transcription. Science, 264, 1455-1458.
36. Haynes, S.R., Dollard, C., Winston, F., Beck, S., Trowsdale, J. and Dawid, I.B. (1992) The bromodomain: a conserved sequence found in human, Drosophila and yeast proteins. Nucleic Acids Res., 20, 2603.
37. Heery, D.M., Zacharewski, T., Pierrat, B., Gronemeyer, H., Chambon, P. and Losson, R. (1993) Efficient transactivation by retinoic acid receptors in yeast requires retinoid X receptors. Proc. Natl Acad. Sci. USA, 90, 4281-4285.
38. Heery, D.M., Pierrat, B., Gronemeyer, H., Chambon, P. and Losson, R. (1994) Homo- and heterodimers of the retinoid X receptor (RXR) activate transcription in yeast. Nucleic Acids Res., 22, 726-731.
39. Hong, H., Kohli, K., Trivedi, A., Johnson, D.L. and Stallcup, M.R. (1996) GRIP1, a novel mouse protein that serves as a transcriptional coactivator in yeast for the hormone binding domains of steroid receptors. Proc. Natl Acad. Sci. USA, 93, 4948-4952.
40. Inoue, S. et al. (1993) Genomic binding-site cloning reveals an estrogen-responsive gene that encodes a RING finger protein. Proc. Natl Acad. Sci. USA, 90, 11117-11121.
41. Kamei, Y. et al. (1996) A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors. Cell, 85, 403-414.
42. Kastner, P., Mark, M. and Chambon, P. (1995) Nonsteroid nuclear receptors: what are genetic studies telling us about their role in real life? Cell, 83, 859-869.
43. Keaveny, M. and Stunnenberg, H.G. (1995) Retinoic acid receptors. In Bauerle, P.A. (ed.), Inducible Gene Expression. Birkhäuser, Boston, MA, Vol. 2, pp. 187-242.
44. Khavari, P.A., Peterson, C.L., Tamkun, J.W., Mendel, D.B. and Crabtree, G.R. (1993) BRG1 contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription. Nature, 366, 170-174.
45. Koonin, E.V., Zhou, S. and Lucchesi, J.C. (1995) The chromo superfamily: new members, duplication of the chromo domain and possible role in delivering transcription regulators to chromatin. Nucleic Acids Res., 23, 4229-4233.
46. Laurent, B.C., Treich, I. and Carlson, M. (1993) The yeast SNF2/SW12 protein has DNA-stimulated ATPase activity required for transcriptional activation. Genes Dev., 7, 583-591.
47. Le Douarin, B. et al. (1995a) The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18. EMBO J., 14, 2020-2033.
48. Le Douarin, B., Pierrat, B., vom Baur, E., Chambon, P. and Losson, R. (1995b) A new version of the two-hybrid assay for detection of protein-protein interactions. Nucleic Acids Res., 23, 876-878.
49. Le Douarin, B., vom Baur, E., Zechel, C., Heery, D., Heine, M., Vivat, V., Gronemeyer, H., Losson, R. and Chambon, P. (1996) Ligand-dependent interaction of nuclear receptors with potential transcriptional intermediary factors (mediators). Philos. Trans. R. Soc. Lond., B351, 569-578.
50. Lee, J.W., Ryan, F., Swaffield, J.C., Johnston, S.A. and Moore, D.A. (1995) Interaction of thyroid-hormone receptor with a conserved transcriptional mediator. Nature, 374, 91-94.
51. Lilley, D.M. (1992) DNA-protein interactions. HMG has DNA wrapped up. Nature, 357, 282-283.
52. Lorentz, A., Ostermann, K., Fleck, O. and Schmidt, H. (1994) Switching gene swi6, involved in repression of silent mating-type loci in fission yeast, encodes a homologue of chromatin-associated proteins from Drosophila and mammals. Gene, 143, 139-143.
53. Lundblad, J.R., Kwok, R.P., Laurance, M.E., Harter, M.L. and Goodman, R.H. (1995) Adenoviral E1A-associated protein p300 as a functional homologue of the transcriptional co-activator CBP. Nature, 374, 85-88.
54. Lygerou, Z., Conesa, C., Lesage, P., Swanson, R.N., Ruet, A., Carlson, M., Sentenac, A. and Seraphin, B. (1994) The yeast BDF1 gene encodes a transcription factor involved in the expression of a broad class of genes including snRNAs. Nucleic Acids Res., 22, 5332-5340.
55. Mangelsdorf, D.J. and Evans, R.M. (1995b) The RXR heterodimers and orphan receptors. Cell, 83, 841-850.
56. Mangelsdorf, D.J. et al. (1995a) The nuclear receptor superfamily: the second decade. Cell, 83, 835-839.
57. Margolin, J.F., Friedman, J.R., Meyer, W.K.-H., Vissing, H., Thiesen, H.-J. and Rauscher, F.J., III (1994) Krüppel-associated boxes are potent transcriptional repression domains. Proc. Natl Acad. Sci. USA, 91, 4509-4513.
58. Messmer, S., Franke, A. and Paro, R. (1992) Analysis of the functional role of the Polycomb chromo domain in Drosophila melanogaster. Genes Dev., 6, 1241-1254.
59. Metzger, D., White, J.H. and Chambon, P. (1988) The human oestrogen receptor functions in yeast. Nature, 334, 31-36.
60. Meyer, M.E., Gronemeyer, H., Turcotte, B., Bocquel, M.T., Tasset, D. and Chambon, P. (1989) Steroid hormone receptors compete for factors that mediate their enhancer function. Cell, 57, 433-442.
61. Nicol, L. and Jeppesen, P. (1994) Human autoimmune sera recognize a conserved 26 kD protein associated with mammalian heterochromatin that is homologous to heterochromatin protein 1 of Drosophila. Chromosome Res., 2, 245-253.
62. Onate, S.A., Tsai, S.Y., Tsai, M.J. and O'Malley, B. (1995) Sequence and characterization of a coactivator for the steroid hormone receptor superfamily. Science, 270, 1354-1357.
63. Parker, M.G. (1993) Steroid and related receptors. Curr. Opin. Cell Biol., 5, 499-504.
64. Paro, R. and Hogness, D.S. (1991) The Polycomb protein shares a homologous domain with a heterochromatin-associated protein of Drosophila. Proc. Natl Acad. Sci. USA, 88, 263-267.
65. Pengue, G. and Lania, L. (1996) Krüppel-associated box-mediated repression of RNA polymerase II promoters is influenced by the arrangement of basal promoter elements. Proc. Natl Acad. Sci. USA, 93, 1015-1020.
66. Peterson, C.L. (1996) Multiples switches to turn on chromatin? Curr. Opin. Genet. Dev., 6, 171-175.
67. Peterson, C.L. and Tamkun, W. (1995) The SWI-SNFcomplex: a chromatin remodeling machine? Trends Biochem. Sci., 20, 143-146.
68. Pierrat, B., Heery, D.M., Lemoine, Y. and Losson, R. (1992) Functional analysis of the human oestrogen receptor using a phenotypic transactivation assay in yeast. Gene, 119, 237-245.
69. Platero, J.S., Hartnett, T. and Eissenberg, J.C. (1995) Functional analysis of the chromo domain of HP1. EMBO J., 14, 3977-3986.
70. Platero, J.S., Sharp, E.J., Adler, P.N. and Eissenberg, J.C. (1996) In vivo assay for protein-protein interactions using Drosophila chromosomes. Chromosoma, 104, 393-404.
71. Powers, J.A. and Eissenberg, J.C. (1993) Overlapping domains of the heterochromatin-associated protein HP1 mediate nuclear localization and heterochromatin binding. J. Cell Biol., 120, 291-299.
72. Quinn, J., Fyrberg, A.M., Ganster, R.W., Schmidt, M.C. and Peterson, C.L. (1996) DNA-binding properties of the yeast SWI/SNF complex. Nature, 379, 844-847.
73. Ramakrishnan, V., Finch, J.T., Graziano, V., Lee, P.L. and Sweet, R.M. (1993) Crystal structure of globular domain of histone H5 and its implications for nucleosome binding. Nature, 362, 219-223.
74. Renaud, J.P., Rochel, N., Ruff, M., Vivat, V., Chambon, P., Gronemeyer, H. and Moras, D. (1995) Crystal structure of the RARγ ligand-binding domain bound to all-trans retinoic acid. Nature, 378, 681-689.
75. Rost, B. and Sander, C. (1994) Conservation and prediction of solvent accessibility in protein families. Proteins, 20, 216-226.
76. Saunders, W.S. et al. (1993) Molecular cloning of a human homologue of Drosophila heterochromatin protein HP1 using anti-centromere autoantibodies with anti-chromo specificity. J. Cell Sci., 104, 573-582.
77. Singh, P.B., Miller, J.R., Pearce, J., Kothary, R., Burton, R.D., Paro, R., James, T.C. and Gaunt, S.J. (1991) A sequence motif found in a Drosophila heterochromatin protein is conserved in animals and plants. Nucleic Acids Res., 19, 789-794.
78. Stayton, C.L. et al. (1994) Cloning and characterization of a new human Xq13 gene encoding a putative helicase. Hum. Mol. Genet., 3, 1957-1964.
79. Sugawara, N., Ivanov, E.L., Fishman-Lobell, J., Ray, B.L., Wu, X. and Haber, J.E. (1995) DNA structure-dependent requirements for yeast RAD genes in gene conversion. Nature, 373, 84-86.
80. Tamkun, J.W., Deuring, R., Scott, M.P., Kissinger, M., Pattatucci, A.M., Kaufman, T.C. and Kennison, J.A. (1992) Brahma: a regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2/SWI2. Cell, 68, 561-572.
81. Tasset, D., Tora, L., Fromental, C., Scheer, E. and Chambon, P. (1990) Distinct classes of transcriptional activating domains function by different mechanisms. Cell, 62, 1177-1187.
82. Thompson, K.A., Wang, B., Argraves, W.S., Giancotti, F.G., Schranck, D.P. and Ruoslahti, E. (1994a) BR140, a novel zinc-finger protein with homology to the TAF250 subunit of TFIID. Biochem. Biophys. Res. Commun., 198, 1143-1152.
83. Thompson, J.D., Higgins, D.G. and Gibson, T.J. (1994b) CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res., 22, 4673-4680.
84. Thummel, C.S. (1995) From embryogenesis to metamorphosis: the regulation and function of Drosophila nuclear receptor superfamily members. Cell, 83, 871-877.
85. Tora, L., White, J., Brou, C., Tasset, D., Webster, N., Scheer, E. and Chambon, P. (1989) The human oestrogen receptor has two independent nonacidic transcriptional activation functions. Cell, 59, 447-487.
86. Tsai, M.J. and O'Malley, B.W. (1994) Molecular mechanisms of action of steroid/thyroid receptor superfamily members. Annu. Rev. Biochem., 63, 451-486.
87. Varga-Weisz, P., Zlatanova, J., Leuba, S.H., Schroth, G.P and van Holde, K. (1994) Binding of histone H1 and H5 and their globular domains to four-way junction DNA. Proc. Natl Acad. Sci. USA, 91, 3525-3529.
88. Voegel, J.J., Heine, M.J.S., Zechel, C., Chambon, P. and Gronemeyer, H. (1996) A 160 kDa transcriptional mediator for the ligand-dependent activation function AF-2 of nuclear receptors. EMBO J., 15, 3667-3675.
89. Vojtek, A.B., Hollenberg, S.M. and Cooper, J.A. (1993) Mammalian Ras interacts directly with the serine/threonine kinase Raf. Cell, 74, 205-214.
90. vom Baur, E. et al. (1996) Differential ligand-dependent interactions between the AF-2 activating domain of nuclear receptors and the putative transcriptional intermediary factors mSUG1 and TIF1. EMBO J., 15, 110-124.
91. Weiler, K.S. and Wakimoto, B.T. (1995) Heterochromatin and gene expression in Drosophila. Annu. Rev. Genet., 29, 577-605.
92. White, R.J., Brou, C., Wu, J., Lutz, Y., Moncollin, V. and Chambon, P. (1992) The acidic transcriptional activator GAL-VP16 acts on preformed template-committed complexes. EMBO J., 11, 2229-2240.
93. Witzgall, R., O'Leary, E., Leaf, A., Önaldi, D. and Bonventre, J.V. (1994) The Krüppel-associated box-A (KRAB-A) domain of zinc finger proteins mediates transcriptional repression. Proc. Natl Acad. Sci. USA, 91, 4514-4518.
94. Wreggett, K.A., Hill, F., James, P.S., Hutchings, A., Butcher, G.W. and Singh, P.B. (1994) A mammalian homologue of Drosophila heterochromatin protein 1 (HP1) is a component of constitutive heterochromatin. Cytogenet. Cell. Genet., 66, 99-103.
95. Wurtz, J.M., Bourguet, W., Renaud, J.P., Vivat, V., Chambon, P., Moras, D. and Gronemeyer, H. (1996) A canonical structure for the ligand binding domain of nuclear receptors. Nature Struct. Biol., 3, 87-94.