-
1
-
-
0034218425
-
Dependence receptors: Links between apoptosis, nervous system development and control of tumorigenesis
-
Mehlen P, Bredesen DE. Dependence receptors: links between apoptosis, nervous system development and control of tumorigenesis. Bull Cancer 2000; 87: 537-41.
-
(2000)
Bull Cancer
, vol.87
, pp. 537-541
-
-
Mehlen, P.1
Bredesen, D.E.2
-
3
-
-
0032134891
-
The Fas/Fas-ligand system: Implications in the antitumor immune response and in the activity of cytotoxic agents
-
Solary E, Micheau O, Dimanche-Boitrel MT, Martin F. The Fas/Fas-ligand system: implications in the antitumor immune response and in the activity of cytotoxic agents. Bull Cancer 1998; 85: 685-94.
-
(1998)
Bull Cancer
, vol.85
, pp. 685-694
-
-
Solary, E.1
Micheau, O.2
Dimanche-Boitrel, M.T.3
Martin, F.4
-
5
-
-
0034616946
-
Apoptotic pathways: Paper wraps stone blunts scissors
-
Green DR. Apoptotic pathways: paper wraps stone blunts scissors. Cell 2000; 102: 1-4.
-
(2000)
Cell
, vol.102
, pp. 1-4
-
-
Green, D.R.1
-
6
-
-
0035368563
-
Apoptotic death sensor: An organelle's alter ego?
-
Bratton SB, Cohen GM. Apoptotic death sensor: an organelle's alter ego? Trends Pharmacol Sci 2001; 22: 306-15.
-
(2001)
Trends Pharmacol Sci
, vol.22
, pp. 306-315
-
-
Bratton, S.B.1
Cohen, G.M.2
-
8
-
-
0030792712
-
Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors
-
Sheridan JP, Marsters SA, Pitti RM, Gurney A, Skubatch M, Baldwin D, et al. Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors. Science 1997; 277: 818-21.
-
(1997)
Science
, vol.277
, pp. 818-821
-
-
Sheridan, J.P.1
Marsters, S.A.2
Pitti, R.M.3
Gurney, A.4
Skubatch, M.5
Baldwin, D.6
-
9
-
-
0032575714
-
Death receptors: Signaling and modulation
-
Ashkenazi A, Dixit VM. Death receptors: signaling and modulation. Science 1998; 281: 1305-8.
-
(1998)
Science
, vol.281
, pp. 1305-1308
-
-
Ashkenazi, A.1
Dixit, V.M.2
-
10
-
-
0032929520
-
Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo
-
Walczak H, Miller RE, Ariail K, Gliniak B, Griffith TS, Kubin M, et al. Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo. Nature Med 1999; 5: 157-63.
-
(1999)
Nature Med
, vol.5
, pp. 157-163
-
-
Walczak, H.1
Miller, R.E.2
Ariail, K.3
Gliniak, B.4
Griffith, T.S.5
Kubin, M.6
-
11
-
-
0032530612
-
Intracellular regulation of TRAIL-induced apoptosis in human melanoma cells
-
Griffith TS, Chin WA, Jackson GC, Lynch DH, Kubin MZ. Intracellular regulation of TRAIL-induced apoptosis in human melanoma cells. J Immunol 1998; 161: 2833-40.
-
(1998)
J Immunol
, vol.161
, pp. 2833-2840
-
-
Griffith, T.S.1
Chin, W.A.2
Jackson, G.C.3
Lynch, D.H.4
Kubin, M.Z.5
-
12
-
-
0035860696
-
Modulation of tumor necrosis factor apoptosis-inducing ligand- induced NF-kappa B activation by inhibition of apical caspases
-
Harper N, Farrow SN, Kaptein A, Cohen GM, MacFarlane M. Modulation of tumor necrosis factor apoptosis-inducing ligand- induced NF-kappa B activation by inhibition of apical caspases. J Biol Chem 2001; 276: 34743-52.
-
(2001)
J Biol Chem
, vol.276
, pp. 34743-34752
-
-
Harper, N.1
Farrow, S.N.2
Kaptein, A.3
Cohen, G.M.4
MacFarlane, M.5
-
13
-
-
0035937420
-
Cell death inhibition: Keeping caspases in check
-
Goyal L. Cell death inhibition: keeping caspases in check. Cell 2001; 104: 805-8.
-
(2001)
Cell
, vol.104
, pp. 805-808
-
-
Goyal, L.1
-
15
-
-
0036097786
-
Keeping killers on a tight leash: Transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins
-
Puthalakath H, Strasser A. Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins. Cell Death Differ 2002; 9: 505-12.
-
(2002)
Cell Death Differ
, vol.9
, pp. 505-512
-
-
Puthalakath, H.1
Strasser, A.2
-
16
-
-
0034640281
-
Noxa, a BH3-only member of the Bcl-2 family and candidate mediatot of p53-induced apoptosis
-
Oda E, Ohki R, Murasawa H, Nemoto J, Shibue T, Yamashita T, et al. Noxa, a BH3-only member of the Bcl-2 family and candidate mediatot of p53-induced apoptosis. Science 2000; 288: 1053-8.
-
(2000)
Science
, vol.288
, pp. 1053-1058
-
-
Oda, E.1
Ohki, R.2
Murasawa, H.3
Nemoto, J.4
Shibue, T.5
Yamashita, T.6
-
17
-
-
0035265823
-
PUMA induces the rapid apoptosis of colorectal cancer cells
-
Yu J, Zhang L, Hwang PM, Kinzler KW, Vogelstein B. PUMA induces the rapid apoptosis of colorectal cancer cells. Mol Cell 2001; 7: 673-82.
-
(2001)
Mol Cell
, vol.7
, pp. 673-682
-
-
Yu, J.1
Zhang, L.2
Hwang, P.M.3
Kinzler, K.W.4
Vogelstein, B.5
-
18
-
-
0035265686
-
PUMA a novel proapoptotic gene, is induced by p53
-
Nakano K, Vousden KH. PUMA, a novel proapoptotic gene, is induced by p53. Mol Cell 2001; 7: 683-94.
-
(2001)
Mol Cell
, vol.7
, pp. 683-694
-
-
Nakano, K.1
Vousden, K.H.2
-
19
-
-
0033104996
-
The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex
-
Puthalakath H, Huang DC, O'Reilly LA, King SM, Strasset A. The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex. Mol Cell 1999; 3: 287-96.
-
(1999)
Mol Cell
, vol.3
, pp. 287-296
-
-
Puthalakath, H.1
Huang, D.C.2
O'Reilly, L.A.3
King, S.M.4
Strasset, A.5
-
20
-
-
0035823238
-
Bmf: A proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis
-
Puthalakath H, Villunger A, O'Reilly LA, Beaumont JG, Coultas L, Cheney RE, et al. Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis. Science 2001; 293: 1829-32.
-
(2001)
Science
, vol.293
, pp. 1829-1832
-
-
Puthalakath, H.1
Villunger, A.2
O'Reilly, L.A.3
Beaumont, J.G.4
Coultas, L.5
Cheney, R.E.6
-
21
-
-
0035876483
-
BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak
-
Zong WX, Lindsten T, Ross AJ, MacGregor GR, Thompson CB. BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak. Genes Dev 2001; 15: 1481-6.
-
(2001)
Genes Dev
, vol.15
, pp. 1481-1486
-
-
Zong, W.X.1
Lindsten, T.2
Ross, A.J.3
MacGregor, G.R.4
Thompson, C.B.5
-
22
-
-
0037096737
-
Critical requirement of BAX for manifestation of apoptosis induced by multiple stimuli in human epithelial cancer cells
-
Theodorakis P, Lomonosova E, Chinnadurai G. Critical requirement of BAX for manifestation of apoptosis induced by multiple stimuli in human epithelial cancer cells. Cancer Res 2002; 62: 3373-6.
-
(2002)
Cancer Res
, vol.62
, pp. 3373-3376
-
-
Theodorakis, P.1
Lomonosova, E.2
Chinnadurai, G.3
-
23
-
-
0036131142
-
Tumor-cell resistance to death receptor-induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax
-
LeBlanc H, Lawrence D, Varfolomeev E, Totpal K, Morlan J, Schow P, et al. Tumor-cell resistance to death receptor-induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax. Nature Med 2002; 8: 274-81.
-
(2002)
Nature Med
, vol.8
, pp. 274-281
-
-
LeBlanc, H.1
Lawrence, D.2
Varfolomeev, E.3
Totpal, K.4
Morlan, J.5
Schow, P.6
-
24
-
-
0034105784
-
Apaf-1 oligomerizes into biologically active approximately 700-kDa and inactive approximately 1.4-MDa apoptosome complexes
-
Cain K, Bratton SB, Langlais C, Walker G, Btown DG, Sun XM, et al. Apaf-1 oligomerizes into biologically active approximately 700-kDa and inactive approximately 1.4-MDa apoptosome complexes. J Biol Chem 2000; 275: 6067-70.
-
(2000)
J Biol Chem
, vol.275
, pp. 6067-6070
-
-
Cain, K.1
Bratton, S.B.2
Langlais, C.3
Walker, G.4
Btown, D.G.5
Sun, X.M.6
-
25
-
-
0036187036
-
Three-dimensional structure of the apoptosome: Implications for assembly, procaspase-9 binding, and activation
-
Acehan D, Jiang X, Morgan DG, Heuser JE, Wang X, Akey CW. Three-dimensional structure of the apoptosome: implications for assembly, procaspase-9 binding, and activation. Mol Cell 2002; 9: 423-32.
-
(2002)
Mol Cell
, vol.9
, pp. 423-432
-
-
Acehan, D.1
Jiang, X.2
Morgan, D.G.3
Heuser, J.E.4
Wang, X.5
Akey, C.W.6
-
26
-
-
0033515883
-
Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition
-
Soengas MS, Alarcon RM, Yoshida H, Giaccia AJ, Hakem R, Mak TW, et al. Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition. Science 1999; 284: 156-9.
-
(1999)
Science
, vol.284
, pp. 156-159
-
-
Soengas, M.S.1
Alarcon, R.M.2
Yoshida, H.3
Giaccia, A.J.4
Hakem, R.5
Mak, T.W.6
-
27
-
-
0035880232
-
Apaf-1 protein deficiency confers resistance to cytochrome c-dependent apoptosis in human leukemic cells
-
Jia L, Srinivasula SM, Liu FT, Newland AC, Fernandes-Alnemri T, Alnemri ES, et al. Apaf-1 protein deficiency confers resistance to cytochrome c-dependent apoptosis in human leukemic cells. Blood 2001; 98: 414-21.
-
(2001)
Blood
, vol.98
, pp. 414-421
-
-
Jia, L.1
Srinivasula, S.M.2
Liu, F.T.3
Newland, A.C.4
Fernandes-Alnemri, T.5
Alnemri, E.S.6
-
28
-
-
0035823503
-
Defective cytochrome c-dependent caspase activation in ovarian cancer cell lines due to diminished or absent apoptotic protease activating factor-1 activity
-
Wolf BB, Schuler M, Li W, Eggers-Sedlet B, Lee W, Tailor P, et al. Defective cytochrome c-dependent caspase activation in ovarian cancer cell lines due to diminished or absent apoptotic protease activating factor-1 activity. J Biol Chem 2001; 276: 34244-51.
-
(2001)
J Biol Chem
, vol.276
, pp. 34244-34251
-
-
Wolf, B.B.1
Schuler, M.2
Li, W.3
Eggers-Sedlet, B.4
Lee, W.5
Tailor, P.6
-
29
-
-
0036468550
-
Dysfunctional apoptosome activation in ovarian cancer: Implications for chemoresistance
-
Liu JR, Opipari AW, Tan L, Jiang Y, Zhang Y, Tang H, et al. Dysfunctional apoptosome activation in ovarian cancer: implications for chemoresistance. Cancer Res 2002; 62: 924-31.
-
(2002)
Cancer Res
, vol.62
, pp. 924-931
-
-
Liu, J.R.1
Opipari, A.W.2
Tan, L.3
Jiang, Y.4
Zhang, Y.5
Tang, H.6
-
30
-
-
0035843169
-
Inactivation of the apoptosis effector Apaf-1 in malignant melanoma
-
Soengas MS, Capodieci P, Polsky D, Mora J, Esteller M, Opitz-Araya X, et al. Inactivation of the apoptosis effector Apaf-1 in malignant melanoma. Nature 2001; 409: 207-11.
-
(2001)
Nature
, vol.409
, pp. 207-211
-
-
Soengas, M.S.1
Capodieci, P.2
Polsky, D.3
Mora, J.4
Esteller, M.5
Opitz-Araya, X.6
-
31
-
-
0034708504
-
Expression and functional analysis of Apaf-1 isoforms. Extra Wd-40 repeat is required for cytochrome c binding and regulated activation of procaspase-9
-
Benedict MA, Hu Y, Inohara N, Nunez G. Expression and functional analysis of Apaf-1 isoforms. Extra Wd-40 repeat is required for cytochrome c binding and regulated activation of procaspase-9. J Biol Chem 2000; 275: 8461-8.
-
(2000)
J Biol Chem
, vol.275
, pp. 8461-8468
-
-
Benedict, M.A.1
Hu, Y.2
Inohara, N.3
Nunez, G.4
-
32
-
-
0037162833
-
Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization
-
Lassus P, Opitz-Araya X, Lazebnik Y. Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization. Science 2002; 297: 1352-4.
-
(2002)
Science
, vol.297
, pp. 1352-1354
-
-
Lassus, P.1
Opitz-Araya, X.2
Lazebnik, Y.3
-
33
-
-
0036141029
-
TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO
-
Deng Y, Lin Y, Wu X. TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO. Genes Dev 2002; 16: 33-45.
-
(2002)
Genes Dev
, vol.16
, pp. 33-45
-
-
Deng, Y.1
Lin, Y.2
Wu, X.3
-
34
-
-
0033047235
-
Apoptosis without caspases: An inefficient molecular guillotine?
-
Borner C, Monney L. Apoptosis without caspases: an inefficient molecular guillotine? Cell Death Differ 1999; 6: 497-507.
-
(1999)
Cell Death Differ
, vol.6
, pp. 497-507
-
-
Borner, C.1
Monney, L.2
-
35
-
-
0035166350
-
On the evolutionary conservation of the cell death pathway: Mitochondtial release of an apoptosis-inducing factor during Dictyostelium discoideum cell death
-
Arnoult D, Tatischeff I, Estaquier J, Girard M, Sureau F, Tissier JP, et al. On the evolutionary conservation of the cell death pathway: mitochondtial release of an apoptosis-inducing factor during Dictyostelium discoideum cell death. Mol Biol Cell 2001; 12: 3016-30.
-
(2001)
Mol Biol Cell
, vol.12
, pp. 3016-3030
-
-
Arnoult, D.1
Tatischeff, I.2
Estaquier, J.3
Girard, M.4
Sureau, F.5
Tissier, J.P.6
-
36
-
-
0035821647
-
Staurosporine induces apoptosis through both caspase-dependent and caspase-independent mechanisms
-
Belmokhtar CA, Hillion J, Segal-Bendirdjian E. Staurosporine induces apoptosis through both caspase-dependent and caspase-independent mechanisms. Oncogene 2001; 20: 3354-62.
-
(2001)
Oncogene
, vol.20
, pp. 3354-3362
-
-
Belmokhtar, C.A.1
Hillion, J.2
Segal-Bendirdjian, E.3
-
37
-
-
0037077254
-
Coupling endoplasmic reticulum stress to the cell death program: An Apaf-1-independent intrinsic pathway
-
Rao RV, Castro-Obregon S, Frankowski H, Schuler M, Stoka V, del Rio G, et al. Coupling endoplasmic reticulum stress to the cell death program: An Apaf-1-independent intrinsic pathway. J Biol Chem 2002; 277: 21836-42.
-
(2002)
J Biol Chem
, vol.277
, pp. 21836-21842
-
-
Rao, R.V.1
Castro-Obregon, S.2
Frankowski, H.3
Schuler, M.4
Stoka, V.5
Del Rio, G.6
-
38
-
-
0035156848
-
Identification of XAF1 as an antagonist of XIAP anti-caspase activity
-
Liston P, Fong WG, Kelly NL, Toji S, Miyazaki T, Conte D, et al. Identification of XAF1 as an antagonist of XIAP anti-caspase activity. Nature Cell Biol 2001; 3: 128-33.
-
(2001)
Nature Cell Biol
, vol.3
, pp. 128-133
-
-
Liston, P.1
Fong, W.G.2
Kelly, N.L.3
Toji, S.4
Miyazaki, T.5
Conte, D.6
-
39
-
-
0035943632
-
The death effector domain-associated factor plays distinct regulatory roles in the nucleus and cytoplasm
-
Zheng L, Schickling O, Peter ME, Lenardo MJ. The death effector domain-associated factor plays distinct regulatory roles in the nucleus and cytoplasm. J Biol Chem 2001; 276: 31945-52.
-
(2001)
J Biol Chem
, vol.276
, pp. 31945-31952
-
-
Zheng, L.1
Schickling, O.2
Peter, M.E.3
Lenardo, M.J.4
-
40
-
-
0034022160
-
Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand
-
Jo M, Kim TH, Seol DW, Esplen JE, Dorko K, Billiar TR. et al. Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand. Nature Med 2000; 6: 564-7.
-
(2000)
Nature Med
, vol.6
, pp. 564-567
-
-
Jo, M.1
Kim, T.H.2
Seol, D.W.3
Esplen, J.E.4
Dorko, K.5
Billiar, T.R.6
-
41
-
-
0034596514
-
Human brain-cell death induced by tumour-necrosis-factor-related apoptosis-inducing ligand (TRAIL)
-
Nitsch R, Bechmann I, Deisz RA, Haas D, Lehmann TN, Wendling U, et al. Human brain-cell death induced by tumour-necrosis-factor-related apoptosis-inducing ligand (TRAIL). Lancet 2000; 356: 827-8.
-
(2000)
Lancet
, vol.356
, pp. 827-828
-
-
Nitsch, R.1
Bechmann, I.2
Deisz, R.A.3
Haas, D.4
Lehmann, T.N.5
Wendling, U.6
-
42
-
-
17944376030
-
Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxiciry
-
Ichikawa K, Liu W, Zhao L, Wang Z, Liu D, Ohtsuka T, et al. Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxiciry. Nature Med 2001; 7: 954-60.
-
(2001)
Nature Med
, vol.7
, pp. 954-960
-
-
Ichikawa, K.1
Liu, W.2
Zhao, L.3
Wang, Z.4
Liu, D.5
Ohtsuka, T.6
-
43
-
-
0035866369
-
Anticancer agents sensitize tumor cells to tumor necrosis factor-related apoptosis-inducing ligand-mediated caspase-8 activation and apoptosis
-
Lacour S, Hammann A, Wotawa A, Corcos L, Solary E, Dimanche-Boitrel MT. Anticancer agents sensitize tumor cells to tumor necrosis factor-related apoptosis-inducing ligand-mediated caspase-8 activation and apoptosis. Cancer Res 2001; 61: 1645-51.
-
(2001)
Cancer Res
, vol.61
, pp. 1645-1651
-
-
Lacour, S.1
Hammann, A.2
Wotawa, A.3
Corcos, L.4
Solary, E.5
Dimanche-Boitrel, M.T.6
-
44
-
-
0036138282
-
Potentiation of the sensitivity of renal cell carcinoma cells to TRAIL-mediated apoptosis by subtoxic concentrations of 5-fluorouracil
-
Mizutani Y, Nakanishi H, Yoshida O, Fukushima M, Bonavida B, Miki T. Potentiation of the sensitivity of renal cell carcinoma cells to TRAIL-mediated apoptosis by subtoxic concentrations of 5-fluorouracil. Eur J Cancer 2002; 38: 167-76.
-
(2002)
Eur J Cancer
, vol.38
, pp. 167-176
-
-
Mizutani, Y.1
Nakanishi, H.2
Yoshida, O.3
Fukushima, M.4
Bonavida, B.5
Miki, T.6
-
45
-
-
0036582832
-
Doxorubicin enhances TRAIL-induced apoptosis in prostate cancer
-
Wu XX, Kakehi Y, Mizutani Y, Kamoto T, Kinoshita H, Isogawa Y, et al. Doxorubicin enhances TRAIL-induced apoptosis in prostate cancer. Int J Oncol 2002; 20: 949-54.
-
(2002)
Int J Oncol
, vol.20
, pp. 949-954
-
-
Wu, X.X.1
Kakehi, Y.2
Mizutani, Y.3
Kamoto, T.4
Kinoshita, H.5
Isogawa, Y.6
-
46
-
-
0036137141
-
Trail activity in human ovarian cancer cells: Potentiation of the action of cytotoxic drugs
-
Vignati S, Codegoni A, Polato F, Broggini M. Trail activity in human ovarian cancer cells: potentiation of the action of cytotoxic drugs. Eur J Cancer 2002; 38: 177-83.
-
(2002)
Eur J Cancer
, vol.38
, pp. 177-183
-
-
Vignati, S.1
Codegoni, A.2
Polato, F.3
Broggini, M.4
-
47
-
-
0037151079
-
An inducible pathway for degradation of FLIP protein sensitizes tumor cells to TRAIL-induced apoptosis
-
Kim Y, Suh N, Sporn M, Reed JC. An inducible pathway for degradation of FLIP protein sensitizes tumor cells to TRAIL-induced apoptosis. J Biol Chem 2002; 277: 22320-9.
-
(2002)
J Biol Chem
, vol.277
, pp. 22320-22329
-
-
Kim, Y.1
Suh, N.2
Sporn, M.3
Reed, J.C.4
-
48
-
-
0037047435
-
Bisindolylmaleimide VIII enhances DR5-mediated apoptosis through the MKK4/JNK/p38 kinase and the mitochondrial pathways
-
Ohtsuka T, Zhou T. Bisindolylmaleimide VIII enhances DR5-mediated apoptosis through the MKK4/JNK/p38 kinase and the mitochondrial pathways. J Biol Chem 2002; 277: 29294-303.
-
(2002)
J Biol Chem
, vol.277
, pp. 29294-29303
-
-
Ohtsuka, T.1
Zhou, T.2
-
49
-
-
0036095959
-
Novel triterpenoid CDDO-Me is a potent inducer of apoptosis and differentiation in acute myelogenous leukemia
-
Konopleva M, Tsao T, Ruvolo P, Stiouf I, Estrov Z, Leysath CE, et al. Novel triterpenoid CDDO-Me is a potent inducer of apoptosis and differentiation in acute myelogenous leukemia. Blood 2002; 99: 326-35.
-
(2002)
Blood
, vol.99
, pp. 326-335
-
-
Konopleva, M.1
Tsao, T.2
Ruvolo, P.3
Stiouf, I.4
Estrov, Z.5
Leysath, C.E.6
-
50
-
-
0037053358
-
The novel triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO) potently enhances apoptosis induced by tumor necrosis factor in human leukemia cells
-
Stadheim TA, Suh N, Ganju N, Sporn MB, Eastman A. The novel triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO) potently enhances apoptosis induced by tumor necrosis factor in human leukemia cells. J Biol Chem 2002; 277: 16448-55.
-
(2002)
J Biol Chem
, vol.277
, pp. 16448-16455
-
-
Stadheim, T.A.1
Suh, N.2
Ganju, N.3
Sporn, M.B.4
Eastman, A.5
-
51
-
-
0035037586
-
The novel triterpenoid CDDO induces apoptosis and differentiation of human osteosarcoma cells by a caspase-8 dependent mechanism
-
Ito Y, Pandey P, Sporn MB, Datta R, Kharbanda S, Kufe D. The novel triterpenoid CDDO induces apoptosis and differentiation of human osteosarcoma cells by a caspase-8 dependent mechanism. Mol Pharmacol 2001; 59: 1094-9.
-
(2001)
Mol Pharmacol
, vol.59
, pp. 1094-1099
-
-
Ito, Y.1
Pandey, P.2
Sporn, M.B.3
Datta, R.4
Kharbanda, S.5
Kufe, D.6
-
52
-
-
0035150803
-
Identificarion of small-molecule inhibitors of interaction between the BH3 domain and Bcl-xL
-
Degterev A, Lugovskoy A, Cardone M, Mulley B, Wagner G, Mitchison T, et al. Identificarion of small-molecule inhibitors of interaction between the BH3 domain and Bcl-xL. Nature Cell Biol 2001; 3: 173-82.
-
(2001)
Nature Cell Biol
, vol.3
, pp. 173-182
-
-
Degterev, A.1
Lugovskoy, A.2
Cardone, M.3
Mulley, B.4
Wagner, G.5
Mitchison, T.6
-
53
-
-
0035942324
-
Biophysical characterization of recombinant human Bcl-2 and its interactions with an inhibitory ligand, antimycin A
-
Kim KM, Giedt CD, Basanez G, O'Neill JW, Hill JJ, Han YH, et al. Biophysical characterization of recombinant human Bcl-2 and its interactions with an inhibitory ligand, antimycin A. Biochemistry 2001; 40: 4911-22.
-
(2001)
Biochemistry
, vol.40
, pp. 4911-4922
-
-
Kim, K.M.1
Giedt, C.D.2
Basanez, G.3
O'Neill, J.W.4
Hill, J.J.5
Han, Y.H.6
-
54
-
-
0035147650
-
Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3
-
Tzung SP, Kim KM, Basanez G, Giedt CD, Simon J, Zimmerberg J, et al. Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3. Nature Cell Biol 2001; 3: 183-91.
-
(2001)
Nature Cell Biol
, vol.3
, pp. 183-191
-
-
Tzung, S.P.1
Kim, K.M.2
Basanez, G.3
Giedt, C.D.4
Simon, J.5
Zimmerberg, J.6
-
55
-
-
0035907464
-
Methodology for optimizing functional miniature proteins based on avian pancreatic polypeptide using phage display
-
Chin JW, Grotzfeld RM, Fabian MA, Schepartz A. Methodology for optimizing functional miniature proteins based on avian pancreatic polypeptide using phage display. Bioorg Med Chem Lett 2001; 11: 1501-5.
-
(2001)
Bioorg Med Chem Lett
, vol.11
, pp. 1501-1505
-
-
Chin, J.W.1
Grotzfeld, R.M.2
Fabian, M.A.3
Schepartz, A.4
-
56
-
-
0032819838
-
Anti-cancer activity of targeted pro-apoptotic peptides
-
Ellerby HM, Arap W, Ellerby LM, Kain R, Andrusiak R, Rio GD, et al. Anti-cancer activity of targeted pro-apoptotic peptides. Nature Med 1999; 5: 1032-8.
-
(1999)
Nature Med
, vol.5
, pp. 1032-1038
-
-
Ellerby, H.M.1
Arap, W.2
Ellerby, L.M.3
Kain, R.4
Andrusiak, R.5
Rio, G.D.6
-
57
-
-
0035866407
-
Apoptosis induction by the photosensitizer verteporfin: Identification of mitochondrial adenine nucleotide translocator as a critical target
-
Belzacq AS, Jacotot E, Vieira HL, Mistro D, Granville DJ, Xie Z, et al. Apoptosis induction by the photosensitizer verteporfin: identification of mitochondrial adenine nucleotide translocator as a critical target. Cancer Res 2001; 61: 1260-4.
-
(2001)
Cancer Res
, vol.61
, pp. 1260-1264
-
-
Belzacq, A.S.1
Jacotot, E.2
Vieira, H.L.3
Mistro, D.4
Granville, D.J.5
Xie, Z.6
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