메뉴 건너뛰기




Volumn 17, Issue 2, 2003, Pages 81-91

Molecular therapies for viral hepatitis

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; ALPHA INTERFERON; ALPHA2 INTERFERON; COMPLEMENTARY RNA; DNA VACCINE; GLYCOPROTEIN E; GLYCOPROTEIN E2; HEPATITIS B VACCINE; LAMIVUDINE; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MEMBRANE PROTEIN; PEGINTERFERON ALPHA2A; PLASMID DNA; RIBAVIRIN; RIBOZYME; UNCLASSIFIED DRUG;

EID: 0037258795     PISSN: 11738804     EISSN: None     Source Type: Journal    
DOI: 10.2165/00063030-200317020-00001     Document Type: Review
Times cited : (10)

References (84)
  • 1
    • 0033024418 scopus 로고    scopus 로고
    • Gene therapy of viral hepatitis and hepatocellular carcinoma
    • Ruiz J, Qian C, Drozdzik M, et al. Gene therapy of viral hepatitis and hepatocellular carcinoma. J Viral Hepat 1999; 6: 17-34
    • (1999) J Viral Hepat , vol.6 , pp. 17-34
    • Ruiz, J.1    Qian, C.2    Drozdzik, M.3
  • 2
    • 0030852745 scopus 로고    scopus 로고
    • Gene therapy for chronic viral hepatitis: Ribozymes, antisense oligonucleotides, and dominant negative mutants
    • von Weizsacker F, Wieland S, Kock J, et al. Gene therapy for chronic viral hepatitis: ribozymes, antisense oligonucleotides, and dominant negative mutants. Hepatology 1997; 26: 251-5
    • (1997) Hepatology , vol.26 , pp. 251-255
    • Von Weizsacker, F.1    Wieland, S.2    Kock, J.3
  • 3
    • 0030830417 scopus 로고    scopus 로고
    • Nucleic acid-based antiviral and gene therapy of chronic hepatitis B infection
    • Wands JR, Geissler M, Putlitz JZ, et al. Nucleic acid-based antiviral and gene therapy of chronic hepatitis B infection. J Gastroenterol Hepatol 1997; 12: S354-69
    • (1997) J Gastroenterol Hepatol , vol.12
    • Wands, J.R.1    Geissler, M.2    Putlitz, J.Z.3
  • 4
    • 0032750621 scopus 로고    scopus 로고
    • 2′-carbohydrate modifications in antisense oligonucleotide therapy: Importance of conformation, configuration and conjugation
    • Manoharan M. 2′-carbohydrate modifications in antisense oligonucleotide therapy: importance of conformation, configuration and conjugation. Biochim Biophys Acta 1999; 1489: 117-30
    • (1999) Biochim Biophys Acta , vol.1489 , pp. 117-130
    • Manoharan, M.1
  • 5
    • 0033544603 scopus 로고    scopus 로고
    • Oligonucleotide N3′→P5′ phosphoramidates as potential therapeutic agents
    • Gryaznov SM. Oligonucleotide N3′→P5′ phosphoramidates as potential therapeutic agents. Biochim Biophys Acta 1999; 1489: 131-40
    • (1999) Biochim Biophys Acta , vol.1489 , pp. 131-140
    • Gryaznov, S.M.1
  • 6
    • 0032697942 scopus 로고    scopus 로고
    • A review of the issues in the pharmacokinetics and toxicology of phosphorothioate antisense oligonucleotides
    • Levin AA. A review of the issues in the pharmacokinetics and toxicology of phosphorothioate antisense oligonucleotides. Biochim Biophys Acta 1999; 1489: 69-84
    • (1999) Biochim Biophys Acta , vol.1489 , pp. 69-84
    • Levin, A.A.1
  • 7
    • 0031050937 scopus 로고    scopus 로고
    • The inhibitory effects of antisense RNA on hepatitis B virus surface antigen synthesis
    • Wu J, Gerber MA. The inhibitory effects of antisense RNA on hepatitis B virus surface antigen synthesis. J Gen Virol 1997; 78: 641-7
    • (1997) J Gen Virol , vol.78 , pp. 641-647
    • Wu, J.1    Gerber, M.A.2
  • 8
    • 0033621041 scopus 로고    scopus 로고
    • Correction of the UDP-glucuronosyltransferase gene defect in the gunn rat model of crigler-najjar syndrome type 1 with a chimeric oligonucleotide
    • Kren BT, Parashar B, Bandyopadhyay P, et al. Correction of the UDP-glucuronosyltransferase gene defect in the gunn rat model of crigler-najjar syndrome type 1 with a chimeric oligonucleotide. Proc Natl Acad Sci U S A 1999; 96: 10349-54
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 10349-10354
    • Kren, B.T.1    Parashar, B.2    Bandyopadhyay, P.3
  • 10
    • 0031688116 scopus 로고    scopus 로고
    • Antisense RNA complementary to hepatitis B virus specifically inhibits viral replication
    • zu Putlitz J, Wieland S, Blum HE, et al. Antisense RNA complementary to hepatitis B virus specifically inhibits viral replication. Gastroenterology 1998; 115: 702-13
    • (1998) Gastroenterology , vol.115 , pp. 702-713
    • Zu Putlitz, J.1    Wieland, S.2    Blum, H.E.3
  • 11
    • 0034167525 scopus 로고    scopus 로고
    • Rous-Whipple Award Lecture: Viruses, immunity, and cancer: Lessons from hepatitis B
    • Chisari FV. Rous-Whipple Award Lecture: viruses, immunity, and cancer: lessons from hepatitis B. Am J Pathol 2000; 156: 1117-32
    • (2000) Am J Pathol , vol.156 , pp. 1117-1132
    • Chisari, F.V.1
  • 12
    • 0027378724 scopus 로고
    • Effect of alpha-interferon treatment in patients with hepatitis B e antigen-positive chronic hepatitis B: A meta-analysis
    • Wong DK, Cheung AM, O'Rourke K, et al. Effect of alpha-interferon treatment in patients with hepatitis B e antigen-positive chronic hepatitis B: a meta-analysis. Ann Intern Med 1993; 119: 312-23
    • (1993) Ann Intern Med , vol.119 , pp. 312-323
    • Wong, D.K.1    Cheung, A.M.2    O'Rourke, K.3
  • 13
    • 0035525235 scopus 로고    scopus 로고
    • Treatment of chronic hepatitis B
    • Yuen MF, Lai CL. Treatment of chronic hepatitis B. Lancet Infect Dis 2001; 1: 232-41
    • (2001) Lancet Infect Dis , vol.1 , pp. 232-241
    • Yuen, M.F.1    Lai, C.L.2
  • 14
    • 0034843958 scopus 로고    scopus 로고
    • Long-term efficacy of interferon alpha-2b and lamivudine in combination compared to lamivudine monotherapy in patients with chronic hepatitis B: An Italian multicenter, randomized trial
    • Barbaro G, Zechini F, Pellicelli AM, et al. Long-term efficacy of interferon alpha-2b and lamivudine in combination compared to lamivudine monotherapy in patients with chronic hepatitis B: an Italian multicenter, randomized trial. J Hepatol 2001; 35: 406-11
    • (2001) J Hepatol , vol.35 , pp. 406-411
    • Barbaro, G.1    Zechini, F.2    Pellicelli, A.M.3
  • 15
    • 0026688793 scopus 로고
    • Specific inhibition of hepatitis B viral gene expression in vitro by targeted antisense oligonucleotides
    • Wu GY, Wu CH. Specific inhibition of hepatitis B viral gene expression in vitro by targeted antisense oligonucleotides. J Biol Chem 1992; 267: 12436-9
    • (1992) J Biol Chem , vol.267 , pp. 12436-12439
    • Wu, G.Y.1    Wu, C.H.2
  • 16
    • 0034968241 scopus 로고    scopus 로고
    • Inhibition of hepadnaviral replication by polyethylenimine-based intravenous delivery of antisense phosphodiester oligodeoxynucleotides to the liver
    • Robaczewska M, Guerret S, Remy JS, et al. Inhibition of hepadnaviral replication by polyethylenimine-based intravenous delivery of antisense phosphodiester oligodeoxynucleotides to the liver. Gene Ther 2001; 8: 874-81
    • (2001) Gene Ther , vol.8 , pp. 874-881
    • Robaczewska, M.1    Guerret, S.2    Remy, J.S.3
  • 17
    • 0033022041 scopus 로고    scopus 로고
    • Combinatorial screening and intracellular antiviral activity of hairpin ribozymes directed against hepatitis B virus
    • zu Putlitz J, Yu Q, Burke JM, et al. Combinatorial screening and intracellular antiviral activity of hairpin ribozymes directed against hepatitis B virus. J Virol 1999; 73: 5381-7
    • (1999) J Virol , vol.73 , pp. 5381-5387
    • Zu Putlitz, J.1    Yu, Q.2    Burke, J.M.3
  • 18
    • 0030743739 scopus 로고    scopus 로고
    • Intracellular application of hairpin ribozyme genes against hepatitis B virus
    • Welch PJ, Tritz R, Yei S, et al. Intracellular application of hairpin ribozyme genes against hepatitis B virus. Gene Ther 1997; 4: 736-43
    • (1997) Gene Ther , vol.4 , pp. 736-743
    • Welch, P.J.1    Tritz, R.2    Yei, S.3
  • 19
    • 0028037417 scopus 로고
    • Characterization of hepatitis B virus core mutants that inhibit viral replication
    • Scaglioni PP, Melegari M, Wands JR. Characterization of hepatitis B virus core mutants that inhibit viral replication. Virology 1994; 205: 112-20
    • (1994) Virology , vol.205 , pp. 112-120
    • Scaglioni, P.P.1    Melegari, M.2    Wands, J.R.3
  • 20
    • 0029953004 scopus 로고    scopus 로고
    • Use of dominant negative mutants of the hepadnaviral core protein as antiviral agents
    • Scaglioni P, Melegari M, Takahashi M, et al. Use of dominant negative mutants of the hepadnaviral core protein as antiviral agents. Hepatology 1996; 24: 1010-7
    • (1996) Hepatology , vol.24 , pp. 1010-1017
    • Scaglioni, P.1    Melegari, M.2    Takahashi, M.3
  • 22
    • 0033943728 scopus 로고    scopus 로고
    • Molecular biology of hepatitis C infection
    • Drazan KE. Molecular biology of hepatitis C infection. Liver Transpl 2000; 6: 396-406
    • (2000) Liver Transpl , vol.6 , pp. 396-406
    • Drazan, K.E.1
  • 23
    • 0036091719 scopus 로고    scopus 로고
    • Hepatitis C advances in antiviral therapy: What is accepted treatment now?
    • McHutchison JG. Hepatitis C advances in antiviral therapy: what is accepted treatment now? J Gastroenterol Hepatol 2002; 17: 431-41
    • (2002) J Gastroenterol Hepatol , vol.17 , pp. 431-441
    • McHutchison, J.G.1
  • 24
    • 0035934568 scopus 로고    scopus 로고
    • Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: A randomised trial
    • Manns MP, McHutchison JG, Gordon SC, et al. Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial. Lancet 2001; 358: 958-65
    • (2001) Lancet , vol.358 , pp. 958-965
    • Manns, M.P.1    McHutchison, J.G.2    Gordon, S.C.3
  • 25
    • 0028303251 scopus 로고
    • Specific inhibition of hepatitis C virus expression by antisense oligodeoxynucleotides: In vitro model for selection of target sequence
    • Wakita T, Wands JR. Specific inhibition of hepatitis C virus expression by antisense oligodeoxynucleotides: in vitro model for selection of target sequence. J Biol Chem 1994; 269: 14205-10
    • (1994) J Biol Chem , vol.269 , pp. 14205-14210
    • Wakita, T.1    Wands, J.R.2
  • 26
    • 0032932079 scopus 로고    scopus 로고
    • Antiviral effects of antisense RNA on hepatitis C virus RNA translation and expression
    • Wakita T, Moradpour D, Tokushihge K, et al. Antiviral effects of antisense RNA on hepatitis C virus RNA translation and expression. J Med Virol 1999; 57: 217-22
    • (1999) J Med Virol , vol.57 , pp. 217-222
    • Wakita, T.1    Moradpour, D.2    Tokushihge, K.3
  • 27
    • 0029972264 scopus 로고    scopus 로고
    • A potential therapeutic application of hairpin ribozymes: In vitro and in vivo studies of gene therapy for hepatitis C virus infection
    • Welch PJ, Tritz R, Yei S, et al. A potential therapeutic application of hairpin ribozymes: in vitro and in vivo studies of gene therapy for hepatitis C virus infection. Gene Ther 1996; 3: 994-1001
    • (1996) Gene Ther , vol.3 , pp. 994-1001
    • Welch, P.J.1    Tritz, R.2    Yei, S.3
  • 28
    • 0032527497 scopus 로고    scopus 로고
    • Ribozyme gene therapy for hepatitis C virus infection
    • Welch PJ, Yei S, Barber JR. Ribozyme gene therapy for hepatitis C virus infection. Clin Diagn Virol 1998; 10: 163-71
    • (1998) Clin Diagn Virol , vol.10 , pp. 163-171
    • Welch, P.J.1    Yei, S.2    Barber, J.R.3
  • 29
    • 0030481468 scopus 로고    scopus 로고
    • Intracellular cleavage of hepatitis C virus RNA and inhibition of viral protein translation by hammerhead ribozymes
    • Sakamoto N, Wu CH, Wu GY. Intracellular cleavage of hepatitis C virus RNA and inhibition of viral protein translation by hammerhead ribozymes. J Clin Invest 1996; 98: 2720-8
    • (1996) J Clin Invest , vol.98 , pp. 2720-2728
    • Sakamoto, N.1    Wu, C.H.2    Wu, G.Y.3
  • 30
    • 17544378561 scopus 로고    scopus 로고
    • Inhibition of hepatitis C virus (HCV)-RNA-dependent translation and replication of a chimeric HCV poliovirus using synthetic stabilized ribozymes
    • Macejak DG, Jensen KL, Jamison SF, et al. Inhibition of hepatitis C virus (HCV)-RNA-dependent translation and replication of a chimeric HCV poliovirus using synthetic stabilized ribozymes. Hepatology 2000; 31: 769-76
    • (2000) Hepatology , vol.31 , pp. 769-776
    • Macejak, D.G.1    Jensen, K.L.2    Jamison, S.F.3
  • 31
    • 0035553604 scopus 로고    scopus 로고
    • Enhanced antiviral effect in cell culture of type 1 interferon and ribozymes targeting HCV RNA
    • Macejak DG, Jensen KL, Pavco PA, et al. Enhanced antiviral effect in cell culture of type 1 interferon and ribozymes targeting HCV RNA. J Viral Hepat 2001; 8: 400-5
    • (2001) J Viral Hepat , vol.8 , pp. 400-405
    • Macejak, D.G.1    Jensen, K.L.2    Pavco, P.A.3
  • 32
    • 0029970824 scopus 로고    scopus 로고
    • Elimination of hepatitis C virus RNA in infected human hepatocytes by adenovirus-mediated expression of ribozymes
    • Lieber A, He CY, Polyak SJ, et al. Elimination of hepatitis C virus RNA in infected human hepatocytes by adenovirus-mediated expression of ribozymes. J Virol 1996; 70: 8782-91
    • (1996) J Virol , vol.70 , pp. 8782-8791
    • Lieber, A.1    He, C.Y.2    Polyak, S.J.3
  • 33
    • 0030021968 scopus 로고    scopus 로고
    • Intracellular inactivation of the hepatitis B virus by cytotoxic T lymphocytes
    • Guidotti LG, Ishikawa T, Hobbs MV, et al. Intracellular inactivation of the hepatitis B virus by cytotoxic T lymphocytes. Immunity 1996; 4: 25-36
    • (1996) Immunity , vol.4 , pp. 25-36
    • Guidotti, L.G.1    Ishikawa, T.2    Hobbs, M.V.3
  • 34
    • 0030965103 scopus 로고    scopus 로고
    • Universal hepatitis B vaccination in Taiwan and the incidence of hepatocellular carcinoma in children
    • Taiwan Childhood Hepatoma Study Group
    • Chang MH, Chen CJ, Lai MS, et al. Universal hepatitis B vaccination in Taiwan and the incidence of hepatocellular carcinoma in children. Taiwan Childhood Hepatoma Study Group. N Engl J Med 1997; 336: 1855-9
    • (1997) N Engl J Med , vol.336 , pp. 1855-1859
    • Chang, M.H.1    Chen, C.J.2    Lai, M.S.3
  • 35
    • 0030903637 scopus 로고    scopus 로고
    • Prevention of primary liver cancer by immunization
    • Zuckerman AJ. Prevention of primary liver cancer by immunization. N Engl J Med 1997; 336: 1906-7
    • (1997) N Engl J Med , vol.336 , pp. 1906-1907
    • Zuckerman, A.J.1
  • 36
    • 0035925668 scopus 로고    scopus 로고
    • Immunotherapy of chronic hepatitis B by anti HBV vaccine: From present to future
    • Michel ML, Pol S, Brechot C, et al. Immunotherapy of chronic hepatitis B by anti HBV vaccine: from present to future. Vaccine 2001; 19: 2395-9
    • (2001) Vaccine , vol.19 , pp. 2395-2399
    • Michel, M.L.1    Pol, S.2    Brechot, C.3
  • 37
    • 0029549730 scopus 로고
    • Immune responses to hepatitis B virus surface and core antigens in mice, monkeys, and pigs after Accell particle-mediated DNA immunization
    • Fuller JT, Fuller DH, McCabe D, et al. Immune responses to hepatitis B virus surface and core antigens in mice, monkeys, and pigs after Accell particle-mediated DNA immunization. Ann N Y Acad Sci 1995; 772: 282-4
    • (1995) Ann N Y Acad Sci , vol.772 , pp. 282-284
    • Fuller, J.T.1    Fuller, D.H.2    McCabe, D.3
  • 38
    • 0034666835 scopus 로고    scopus 로고
    • Multiepitopic HLA-A*0201-restricted immune response against hepatitis B surface antigen after DNA-based immunization
    • Loirat D, Lemonnier FA, Michel ML. Multiepitopic HLA-A*0201-restricted immune response against hepatitis B surface antigen after DNA-based immunization. J Immunol 2000; 165: 4748-55
    • (2000) J Immunol , vol.165 , pp. 4748-4755
    • Loirat, D.1    Lemonnier, F.A.2    Michel, M.L.3
  • 39
    • 0034880464 scopus 로고    scopus 로고
    • DNA vaccines for prophylactic or therapeutic immunization against hepatitis B
    • Michel ML, Loirat D. DNA vaccines for prophylactic or therapeutic immunization against hepatitis B. Intervirology 2001; 44: 78-87
    • (2001) Intervirology , vol.44 , pp. 78-87
    • Michel, M.L.1    Loirat, D.2
  • 40
    • 0029101242 scopus 로고
    • Nucleic acid vaccination primes hepatitis B virus surface antigen-specific cytotoxic T lymphocytes in nonresponder mice
    • Schirmbeck R, Bohm W, Ando K, et al. Nucleic acid vaccination primes hepatitis B virus surface antigen-specific cytotoxic T lymphocytes in nonresponder mice. J Virol 1995; 69: 5929-34
    • (1995) J Virol , vol.69 , pp. 5929-5934
    • Schirmbeck, R.1    Bohm, W.2    Ando, K.3
  • 41
    • 0033120573 scopus 로고    scopus 로고
    • Utilization of MHC class I transgenic mice for development of minigene DNA vaccines encoding multiple HLA-restricted CTL epitopes
    • Ishioka GY, Fikes J, Hermanson G, et al. Utilization of MHC class I transgenic mice for development of minigene DNA vaccines encoding multiple HLA-restricted CTL epitopes. J Immunol 1999; 162: 3915-25
    • (1999) J Immunol , vol.162 , pp. 3915-3925
    • Ishioka, G.Y.1    Fikes, J.2    Hermanson, G.3
  • 42
    • 0032518355 scopus 로고    scopus 로고
    • In vivo induction of specific cytotoxic T lymphocytes in mice and rhesus macaques immunized with DNA vector encoding an HIV epitope fused with hepatitis B surface antigen
    • Le Borgne S, Mancini M, Le Grand R, et al. In vivo induction of specific cytotoxic T lymphocytes in mice and rhesus macaques immunized with DNA vector encoding an HIV epitope fused with hepatitis B surface antigen. Virology 1998; 240: 304-15
    • (1998) Virology , vol.240 , pp. 304-315
    • Le Borgne, S.1    Mancini, M.2    Le Grand, R.3
  • 43
    • 0032077308 scopus 로고    scopus 로고
    • Differential cellular and humoral immune responses to HCV core and HBV envelope proteins after genetic immunizations using chimeric constructs
    • Geissler M, Tokushige K, Wakita T, et al. Differential cellular and humoral immune responses to HCV core and HBV envelope proteins after genetic immunizations using chimeric constructs. Vaccine 1998; 16: 857-67
    • (1998) Vaccine , vol.16 , pp. 857-867
    • Geissler, M.1    Tokushige, K.2    Wakita, T.3
  • 44
    • 0029084640 scopus 로고
    • DNA-based immunization with chimeric vectors for the induction of immune responses against the hepatitis C virus nucleocapsid
    • Major ME, Vitvitski L, Mink MA, et al. DNA-based immunization with chimeric vectors for the induction of immune responses against the hepatitis C virus nucleocapsid. J Virol 1995; 69: 5798-805
    • (1995) J Virol , vol.69 , pp. 5798-5805
    • Major, M.E.1    Vitvitski, L.2    Mink, M.A.3
  • 45
    • 0030239828 scopus 로고    scopus 로고
    • Induction of NK activity in murine and human cells by CpG motifs in oligodeoxynucleotides and bacterial DNA
    • Ballas ZK, Rasmussen WL, Krieg AM. Induction of NK activity in murine and human cells by CpG motifs in oligodeoxynucleotides and bacterial DNA. J Immunol 1996; 157: 1840-5
    • (1996) J Immunol , vol.157 , pp. 1840-1845
    • Ballas, Z.K.1    Rasmussen, W.L.2    Krieg, A.M.3
  • 46
    • 0029984358 scopus 로고    scopus 로고
    • CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma
    • Klinman DM, Yi AK, Beaucage SL, et al. CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma. Proc Natl Acad Sci U S A 1996; 93: 2879-83
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 2879-2883
    • Klinman, D.M.1    Yi, A.K.2    Beaucage, S.L.3
  • 47
    • 0034046182 scopus 로고    scopus 로고
    • DNA vaccines: Immunology, application, and optimization
    • Gurunathan S, Klinman DM, Seder RA. DNA vaccines: immunology, application, and optimization. Annu Rev Immunol 2000; 18: 927-74
    • (2000) Annu Rev Immunol , vol.18 , pp. 927-974
    • Gurunathan, S.1    Klinman, D.M.2    Seder, R.A.3
  • 48
    • 0033521543 scopus 로고    scopus 로고
    • DNA vaccination: Transfection and activation of dendritic cells as key events for immunity
    • Akbari O, Panjwani N, Garcia S, et al. DNA vaccination: transfection and activation of dendritic cells as key events for immunity. J Exp Med 1999; 189: 169-78
    • (1999) J Exp Med , vol.189 , pp. 169-178
    • Akbari, O.1    Panjwani, N.2    Garcia, S.3
  • 49
    • 1842299314 scopus 로고    scopus 로고
    • Characterization of humoral and CD4+ cellular responses after genetic immunization with retroviral vectors expressing different forms of the hepatitis B virus core and e antigens
    • Sallberg M, Townsend K, Chen M, et al. Characterization of humoral and CD4+ cellular responses after genetic immunization with retroviral vectors expressing different forms of the hepatitis B virus core and e antigens. J Virol 1997; 71: 5295-303
    • (1997) J Virol , vol.71 , pp. 5295-5303
    • Sallberg, M.1    Townsend, K.2    Chen, M.3
  • 50
    • 0025762458 scopus 로고
    • Development of immunogenic recombinant Oka varicella vaccine expressing hepatitis B virus surface antigen
    • Shiraki K, Hayakawa Y, Mori H, et al. Development of immunogenic recombinant Oka varicella vaccine expressing hepatitis B virus surface antigen. J Gen Virol 1991; 72: 1393-9
    • (1991) J Gen Virol , vol.72 , pp. 1393-1399
    • Shiraki, K.1    Hayakawa, Y.2    Mori, H.3
  • 51
    • 0031834248 scopus 로고    scopus 로고
    • Use of SV40 to immunize against hepatitis B surface antigen: Implications for the use of SV40 for gene transduction and its use as an immunizing agent
    • Kondo R, Feitelson MA, Strayer DS. Use of SV40 to immunize against hepatitis B surface antigen: implications for the use of SV40 for gene transduction and its use as an immunizing agent. Gene Ther 1998; 5: 575-82
    • (1998) Gene Ther , vol.5 , pp. 575-582
    • Kondo, R.1    Feitelson, M.A.2    Strayer, D.S.3
  • 52
    • 0033605350 scopus 로고    scopus 로고
    • DNA-mediated immunization to hepatitis B virus envelope proteins: preS antigen secretion enhances the humoral response
    • Prange R, Werr M. DNA-mediated immunization to hepatitis B virus envelope proteins: preS antigen secretion enhances the humoral response. Vaccine 1999; 17: 617-23
    • (1999) Vaccine , vol.17 , pp. 617-623
    • Prange, R.1    Werr, M.2
  • 54
    • 0033868504 scopus 로고    scopus 로고
    • Vaccine development for hepatitis C
    • Lechmann M, Liang TJ. Vaccine development for hepatitis C. Semin Liver Dis 2000; 20: 211-26
    • (2000) Semin Liver Dis , vol.20 , pp. 211-226
    • Lechmann, M.1    Liang, T.J.2
  • 55
    • 17544368390 scopus 로고    scopus 로고
    • Evaluation of hepatitis C virus glycoprotein E2 for vaccine design: An endoplasmic reticulum-retained recombinant protein is superior to secreted recombinant protein and DNA-based vaccine candidates
    • Heile JM, Fong YL, Rosa D, et al. Evaluation of hepatitis C virus glycoprotein E2 for vaccine design: an endoplasmic reticulum-retained recombinant protein is superior to secreted recombinant protein and DNA-based vaccine candidates. J Virol 2000; 74: 6885-92
    • (2000) J Virol , vol.74 , pp. 6885-6892
    • Heile, J.M.1    Fong, Y.L.2    Rosa, D.3
  • 56
    • 0034466814 scopus 로고    scopus 로고
    • Enhancing B- and T-cell immune response to a hepatitis C virus E2 DNA vaccine by intramuscular electrical gene transfer
    • Zucchelli S, Capone S, Fattori E, et al. Enhancing B- and T-cell immune response to a hepatitis C virus E2 DNA vaccine by intramuscular electrical gene transfer. J Virol 2000; 74: 11598-607
    • (2000) J Virol , vol.74 , pp. 11598-11607
    • Zucchelli, S.1    Capone, S.2    Fattori, E.3
  • 57
    • 0033848911 scopus 로고    scopus 로고
    • Vaccination of chimpanzees with plasmid DNA encoding the hepatitis C virus (HCV) envelope E2 protein modified the infection after challenge with homologous monoclonal HCV
    • Forns X, Payette PJ, Ma X, et al. Vaccination of chimpanzees with plasmid DNA encoding the hepatitis C virus (HCV) envelope E2 protein modified the infection after challenge with homologous monoclonal HCV. Hepatology 2000; 32: 618-25
    • (2000) Hepatology , vol.32 , pp. 618-625
    • Forns, X.1    Payette, P.J.2    Ma, X.3
  • 58
    • 0028038280 scopus 로고
    • Sequence analysis of the core gene of 14 hepatitis C virus genotypes
    • Bukh J, Purcell RH, Miller RH. Sequence analysis of the core gene of 14 hepatitis C virus genotypes. Proc Natl Acad Sci U S A 1994; 91: 8239-43
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 8239-8243
    • Bukh, J.1    Purcell, R.H.2    Miller, R.H.3
  • 59
    • 0032870465 scopus 로고    scopus 로고
    • Immune selection and genetic sequence variation in core and envelope regions of hepatitis C virus
    • Christie JM, Chapel H, Chapman RW, et al. Immune selection and genetic sequence variation in core and envelope regions of hepatitis C virus. Hepatology 1999; 30: 1037-44
    • (1999) Hepatology , vol.30 , pp. 1037-1044
    • Christie, J.M.1    Chapel, H.2    Chapman, R.W.3
  • 60
    • 0029971032 scopus 로고    scopus 로고
    • Expression and immune response to hepatitis C virus core DNA-based vaccine constructs
    • Tokushige K, Wakita T, Pachuk C, et al. Expression and immune response to hepatitis C virus core DNA-based vaccine constructs. Hepatology 1996; 24: 14-20
    • (1996) Hepatology , vol.24 , pp. 14-20
    • Tokushige, K.1    Wakita, T.2    Pachuk, C.3
  • 61
    • 0034053296 scopus 로고    scopus 로고
    • Properties of the hepatitis C virus core protein: A structural protein that modulates cellular processes
    • McLauchlan J. Properties of the hepatitis C virus core protein: a structural protein that modulates cellular processes. J Viral Hepat 2000; 7: 2-14
    • (2000) J Viral Hepat , vol.7 , pp. 2-14
    • McLauchlan, J.1
  • 62
    • 0035284757 scopus 로고    scopus 로고
    • Characterization of hepatitis C virus core-specific immune responses primed in rhesus macaques by a nonclassical ISCOM vaccine
    • Polakos NK, Drane D, Cox J, et al. Characterization of hepatitis C virus core-specific immune responses primed in rhesus macaques by a nonclassical ISCOM vaccine. J Immunol 2001; 166: 3589-98
    • (2001) J Immunol , vol.166 , pp. 3589-3598
    • Polakos, N.K.1    Drane, D.2    Cox, J.3
  • 63
    • 0032212215 scopus 로고    scopus 로고
    • Genetic immunization generates cellular and humoral immune responses against the nonstructural proteins of the hepatitis C virus in a murine model
    • Encke J, zu Putlitz J, Geissler M, et al. Genetic immunization generates cellular and humoral immune responses against the nonstructural proteins of the hepatitis C virus in a murine model. J Immunol 1998; 161: 4917-23
    • (1998) J Immunol , vol.161 , pp. 4917-4923
    • Encke, J.1    Zu Putlitz, J.2    Geissler, M.3
  • 64
    • 0035192083 scopus 로고    scopus 로고
    • Different hepatitis C virus nonstructural protein 3 (Ns3)-DNA-expressing vaccines induce in HLA-A2.1 transgenic mice stable cytotoxic T lymphocytes that target one major epitope
    • Brinster C, Muguet S, Lone YC, et al. Different hepatitis C virus nonstructural protein 3 (Ns3)-DNA- expressing vaccines induce in HLA-A2.1 transgenic mice stable cytotoxic T lymphocytes that target one major epitope. Hepatology 2001; 34: 1206-17
    • (2001) Hepatology , vol.34 , pp. 1206-1217
    • Brinster, C.1    Muguet, S.2    Lone, Y.C.3
  • 65
    • 0034766336 scopus 로고    scopus 로고
    • Oral immunization with HCV-NS3-transformed Salmonella: Induction of HCV- specific CTL in a transgenic mouse model
    • Wedemeyer H, Gagneten S, Davis A, et al. Oral immunization with HCV-NS3-transformed Salmonella: induction of HCV- specific CTL in a transgenic mouse model. Gastroenterology 2001; 121: 1158-66
    • (2001) Gastroenterology , vol.121 , pp. 1158-1166
    • Wedemeyer, H.1    Gagneten, S.2    Davis, A.3
  • 66
    • 0035202920 scopus 로고    scopus 로고
    • Genetic immunization of wild-type and hepatitis C virus transgenic mice reveals a hierarchy of cellular immune response and tolerance induction against hepatitis C virus structural proteins
    • Satoi J, Murata K, Lechmann M, et al. Genetic immunization of wild-type and hepatitis C virus transgenic mice reveals a hierarchy of cellular immune response and tolerance induction against hepatitis C virus structural proteins. J Virol 2001; 75: 12121-7
    • (2001) J Virol , vol.75 , pp. 12121-12127
    • Satoi, J.1    Murata, K.2    Lechmann, M.3
  • 67
    • 0034531322 scopus 로고    scopus 로고
    • Development of a plant-derived subunit vaccine candidate against hepatitis C virus
    • Nemchinov LG, Liang TJ, Rifaat MM, et al. Development of a plant-derived subunit vaccine candidate against hepatitis C virus. Arch Virol 2000; 145: 2557-73
    • (2000) Arch Virol , vol.145 , pp. 2557-2573
    • Nemchinov, L.G.1    Liang, T.J.2    Rifaat, M.M.3
  • 68
    • 0029461123 scopus 로고
    • Targeted delivery of antisense DNA in woodchuck hepatitis virus-infected woodchucks
    • Bartholomew RM, Carmichael EP, Findeis MA, et al. Targeted delivery of antisense DNA in woodchuck hepatitis virus-infected woodchucks. J Viral Hepat 1995; 2: 273-8
    • (1995) J Viral Hepat , vol.2 , pp. 273-278
    • Bartholomew, R.M.1    Carmichael, E.P.2    Findeis, M.A.3
  • 69
    • 0032945030 scopus 로고    scopus 로고
    • Hepatocyte-directed gene delivery by receptor-mediated endocytosis
    • Smith RM, Wu GY. Hepatocyte-directed gene delivery by receptor-mediated endocytosis. Semin Liver Dis 1999; 19: 83-92
    • (1999) Semin Liver Dis , vol.19 , pp. 83-92
    • Smith, R.M.1    Wu, G.Y.2
  • 70
    • 0030662074 scopus 로고    scopus 로고
    • Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells
    • Ivics Z, Hackett PB, Plasterk RH, et al. Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells. Cell 1997; 91: 501-10
    • (1997) Cell , vol.91 , pp. 501-510
    • Ivics, Z.1    Hackett, P.B.2    Plasterk, R.H.3
  • 71
    • 0034103009 scopus 로고    scopus 로고
    • Somatic integration and long-term transgene expression in normal and haemophilic mice using a DNA transposon system
    • Yant SR, Meuse L, Chiu W, et al. Somatic integration and long-term transgene expression in normal and haemophilic mice using a DNA transposon system. Nat Genet 2000; 25: 35-41
    • (2000) Nat Genet , vol.25 , pp. 35-41
    • Yant, S.R.1    Meuse, L.2    Chiu, W.3
  • 72
    • 0003109621 scopus 로고    scopus 로고
    • Targeted inhibition of hepatitis B virus gene expression: A gene therapy approach
    • Tung FYT, Bowen SW. Targeted inhibition of hepatitis B virus gene expression: a gene therapy approach. Front Biosci 1998; 3: a11-5
    • (1998) Front Biosci , vol.3
    • Tung, F.Y.T.1    Bowen, S.W.2
  • 73
    • 0032925803 scopus 로고    scopus 로고
    • Retroviral vectors for liver-directed gene therapy
    • Kalpana GV. Retroviral vectors for liver-directed gene therapy. Semin Liver Dis 1999; 19: 27-37
    • (1999) Semin Liver Dis , vol.19 , pp. 27-37
    • Kalpana, G.V.1
  • 74
    • 0033616680 scopus 로고    scopus 로고
    • Sustained correction of bleeding disorder in hemophilia B mice by gene therapy
    • Wang L, Takabe K, Bidlingmaier SM, et al. Sustained correction of bleeding disorder in hemophilia B mice by gene therapy. Proc Natl Acad Sci U S A 1999; 96: 3906-10
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 3906-3910
    • Wang, L.1    Takabe, K.2    Bidlingmaier, S.M.3
  • 75
    • 0033735275 scopus 로고    scopus 로고
    • SV40-based gene therapy vectors: Turning an adversary into a friend
    • Strayer DS. SV40-based gene therapy vectors: turning an adversary into a friend. Curr Opin Mol Ther 2000; 2: 570-8
    • (2000) Curr Opin Mol Ther , vol.2 , pp. 570-578
    • Strayer, D.S.1
  • 76
    • 0032942075 scopus 로고    scopus 로고
    • Gene delivery to the liver using simian virus 40-derived vectors
    • Strayer DS, Zern MA. Gene delivery to the liver using simian virus 40-derived vectors. Semin Liver Dis 1999; 19: 71-81
    • (1999) Semin Liver Dis , vol.19 , pp. 71-81
    • Strayer, D.S.1    Zern, M.A.2
  • 77
    • 0032948552 scopus 로고    scopus 로고
    • Adenovirus-mediated gene therapy of liver diseases
    • Ilan Y, Saito H, Thummala NR, et al. Adenovirus-mediated gene therapy of liver diseases. Semin Liver Dis 1999; 19: 49-59
    • (1999) Semin Liver Dis , vol.19 , pp. 49-59
    • Ilan, Y.1    Saito, H.2    Thummala, N.R.3
  • 78
    • 0031778879 scopus 로고    scopus 로고
    • Role of E4 in eliciting CD4 T-cell and B-cell responses to adenovirus vectors delivered to murine and nonhuman primate lungs
    • Chirmule N, Hughes JV, Gao GP, et al. Role of E4 in eliciting CD4 T-cell and B-cell responses to adenovirus vectors delivered to murine and nonhuman primate lungs. J Virol 1998; 72: 6138-45
    • (1998) J Virol , vol.72 , pp. 6138-6145
    • Chirmule, N.1    Hughes, J.V.2    Gao, G.P.3
  • 79
    • 0032530110 scopus 로고    scopus 로고
    • Cellular immune response to adenoviral vector infected cells does not require de novo viral gene expression: Implications for gene therapy
    • Kafri T, Morgan D, Krahl T, et al. Cellular immune response to adenoviral vector infected cells does not require de novo viral gene expression: implications for gene therapy. Proc Natl Acad Sci U S A 1998; 95: 11377-82
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 11377-11382
    • Kafri, T.1    Morgan, D.2    Krahl, T.3
  • 80
    • 0036052121 scopus 로고    scopus 로고
    • A non-immunogenic adenoviral vector, coexpressing CTLA4Ig and bilirubin-uridine-diphosphoglucuronateglucuronosyltransferase permits long-term, repeatable transgene expression in the Gunn rat model of Crigler-Najjar syndrome
    • Thummala NR, Ghosh SS, Lee SW, et al. A non-immunogenic adenoviral vector, coexpressing CTLA4Ig and bilirubin-uridine-diphosphoglucuronateglucuronosyltransferase permits long-term, repeatable transgene expression in the Gunn rat model of Crigler-Najjar syndrome. Gene Ther 2002; 9: 981-90
    • (2002) Gene Ther , vol.9 , pp. 981-990
    • Thummala, N.R.1    Ghosh, S.S.2    Lee, S.W.3
  • 81
    • 0030775646 scopus 로고    scopus 로고
    • Stable in vivo gene transduction via a novel adenoviral/retroviral chimeric vector
    • Feng M, Jackson Jr WH, Goldman CK, et al. Stable in vivo gene transduction via a novel adenoviral/retroviral chimeric vector. Nat Biotechnol 1997; 15: 866-70
    • (1997) Nat Biotechnol , vol.15 , pp. 866-870
    • Feng, M.1    Jackson W.H., Jr.2    Goldman, C.K.3
  • 82
    • 0033057474 scopus 로고    scopus 로고
    • Site-specific integration mediated by a hybrid adenovirus/adeno-associated virus vector
    • Recchia A, Parks RJ, Lamartina S, et al. Site-specific integration mediated by a hybrid adenovirus/adeno-associated virus vector. Proc Natl Acad Sci U S A 1999; 96: 2615-20
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 2615-2620
    • Recchia, A.1    Parks, R.J.2    Lamartina, S.3
  • 83
    • 0030280036 scopus 로고    scopus 로고
    • The potential of extrachromosomal replicating vectors for gene therapy
    • Calos MP. The potential of extrachromosomal replicating vectors for gene therapy. Trends Genet 1996; 12: 463-6
    • (1996) Trends Genet , vol.12 , pp. 463-466
    • Calos, M.P.1
  • 84
    • 0034168963 scopus 로고    scopus 로고
    • Stable transduction of actively dividing cells via a novel adenoviral/episomal vector
    • Leblois L, Roche C, Di Falco ND, et al. Stable transduction of actively dividing cells via a novel adenoviral/episomal vector. Mol Ther 2000; 1: 314-22
    • (2000) Mol Ther , vol.1 , pp. 314-322
    • Leblois, L.1    Roche, C.2    Di Falco, N.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.