-
1
-
-
0033024418
-
Gene therapy of viral hepatitis and hepatocellular carcinoma
-
Ruiz J, Qian C, Drozdzik M, et al. Gene therapy of viral hepatitis and hepatocellular carcinoma. J Viral Hepat 1999; 6: 17-34
-
(1999)
J Viral Hepat
, vol.6
, pp. 17-34
-
-
Ruiz, J.1
Qian, C.2
Drozdzik, M.3
-
2
-
-
0030852745
-
Gene therapy for chronic viral hepatitis: Ribozymes, antisense oligonucleotides, and dominant negative mutants
-
von Weizsacker F, Wieland S, Kock J, et al. Gene therapy for chronic viral hepatitis: ribozymes, antisense oligonucleotides, and dominant negative mutants. Hepatology 1997; 26: 251-5
-
(1997)
Hepatology
, vol.26
, pp. 251-255
-
-
Von Weizsacker, F.1
Wieland, S.2
Kock, J.3
-
3
-
-
0030830417
-
Nucleic acid-based antiviral and gene therapy of chronic hepatitis B infection
-
Wands JR, Geissler M, Putlitz JZ, et al. Nucleic acid-based antiviral and gene therapy of chronic hepatitis B infection. J Gastroenterol Hepatol 1997; 12: S354-69
-
(1997)
J Gastroenterol Hepatol
, vol.12
-
-
Wands, J.R.1
Geissler, M.2
Putlitz, J.Z.3
-
4
-
-
0032750621
-
2′-carbohydrate modifications in antisense oligonucleotide therapy: Importance of conformation, configuration and conjugation
-
Manoharan M. 2′-carbohydrate modifications in antisense oligonucleotide therapy: importance of conformation, configuration and conjugation. Biochim Biophys Acta 1999; 1489: 117-30
-
(1999)
Biochim Biophys Acta
, vol.1489
, pp. 117-130
-
-
Manoharan, M.1
-
5
-
-
0033544603
-
Oligonucleotide N3′→P5′ phosphoramidates as potential therapeutic agents
-
Gryaznov SM. Oligonucleotide N3′→P5′ phosphoramidates as potential therapeutic agents. Biochim Biophys Acta 1999; 1489: 131-40
-
(1999)
Biochim Biophys Acta
, vol.1489
, pp. 131-140
-
-
Gryaznov, S.M.1
-
6
-
-
0032697942
-
A review of the issues in the pharmacokinetics and toxicology of phosphorothioate antisense oligonucleotides
-
Levin AA. A review of the issues in the pharmacokinetics and toxicology of phosphorothioate antisense oligonucleotides. Biochim Biophys Acta 1999; 1489: 69-84
-
(1999)
Biochim Biophys Acta
, vol.1489
, pp. 69-84
-
-
Levin, A.A.1
-
7
-
-
0031050937
-
The inhibitory effects of antisense RNA on hepatitis B virus surface antigen synthesis
-
Wu J, Gerber MA. The inhibitory effects of antisense RNA on hepatitis B virus surface antigen synthesis. J Gen Virol 1997; 78: 641-7
-
(1997)
J Gen Virol
, vol.78
, pp. 641-647
-
-
Wu, J.1
Gerber, M.A.2
-
8
-
-
0033621041
-
Correction of the UDP-glucuronosyltransferase gene defect in the gunn rat model of crigler-najjar syndrome type 1 with a chimeric oligonucleotide
-
Kren BT, Parashar B, Bandyopadhyay P, et al. Correction of the UDP-glucuronosyltransferase gene defect in the gunn rat model of crigler-najjar syndrome type 1 with a chimeric oligonucleotide. Proc Natl Acad Sci U S A 1999; 96: 10349-54
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 10349-10354
-
-
Kren, B.T.1
Parashar, B.2
Bandyopadhyay, P.3
-
10
-
-
0031688116
-
Antisense RNA complementary to hepatitis B virus specifically inhibits viral replication
-
zu Putlitz J, Wieland S, Blum HE, et al. Antisense RNA complementary to hepatitis B virus specifically inhibits viral replication. Gastroenterology 1998; 115: 702-13
-
(1998)
Gastroenterology
, vol.115
, pp. 702-713
-
-
Zu Putlitz, J.1
Wieland, S.2
Blum, H.E.3
-
11
-
-
0034167525
-
Rous-Whipple Award Lecture: Viruses, immunity, and cancer: Lessons from hepatitis B
-
Chisari FV. Rous-Whipple Award Lecture: viruses, immunity, and cancer: lessons from hepatitis B. Am J Pathol 2000; 156: 1117-32
-
(2000)
Am J Pathol
, vol.156
, pp. 1117-1132
-
-
Chisari, F.V.1
-
12
-
-
0027378724
-
Effect of alpha-interferon treatment in patients with hepatitis B e antigen-positive chronic hepatitis B: A meta-analysis
-
Wong DK, Cheung AM, O'Rourke K, et al. Effect of alpha-interferon treatment in patients with hepatitis B e antigen-positive chronic hepatitis B: a meta-analysis. Ann Intern Med 1993; 119: 312-23
-
(1993)
Ann Intern Med
, vol.119
, pp. 312-323
-
-
Wong, D.K.1
Cheung, A.M.2
O'Rourke, K.3
-
13
-
-
0035525235
-
Treatment of chronic hepatitis B
-
Yuen MF, Lai CL. Treatment of chronic hepatitis B. Lancet Infect Dis 2001; 1: 232-41
-
(2001)
Lancet Infect Dis
, vol.1
, pp. 232-241
-
-
Yuen, M.F.1
Lai, C.L.2
-
14
-
-
0034843958
-
Long-term efficacy of interferon alpha-2b and lamivudine in combination compared to lamivudine monotherapy in patients with chronic hepatitis B: An Italian multicenter, randomized trial
-
Barbaro G, Zechini F, Pellicelli AM, et al. Long-term efficacy of interferon alpha-2b and lamivudine in combination compared to lamivudine monotherapy in patients with chronic hepatitis B: an Italian multicenter, randomized trial. J Hepatol 2001; 35: 406-11
-
(2001)
J Hepatol
, vol.35
, pp. 406-411
-
-
Barbaro, G.1
Zechini, F.2
Pellicelli, A.M.3
-
15
-
-
0026688793
-
Specific inhibition of hepatitis B viral gene expression in vitro by targeted antisense oligonucleotides
-
Wu GY, Wu CH. Specific inhibition of hepatitis B viral gene expression in vitro by targeted antisense oligonucleotides. J Biol Chem 1992; 267: 12436-9
-
(1992)
J Biol Chem
, vol.267
, pp. 12436-12439
-
-
Wu, G.Y.1
Wu, C.H.2
-
16
-
-
0034968241
-
Inhibition of hepadnaviral replication by polyethylenimine-based intravenous delivery of antisense phosphodiester oligodeoxynucleotides to the liver
-
Robaczewska M, Guerret S, Remy JS, et al. Inhibition of hepadnaviral replication by polyethylenimine-based intravenous delivery of antisense phosphodiester oligodeoxynucleotides to the liver. Gene Ther 2001; 8: 874-81
-
(2001)
Gene Ther
, vol.8
, pp. 874-881
-
-
Robaczewska, M.1
Guerret, S.2
Remy, J.S.3
-
17
-
-
0033022041
-
Combinatorial screening and intracellular antiviral activity of hairpin ribozymes directed against hepatitis B virus
-
zu Putlitz J, Yu Q, Burke JM, et al. Combinatorial screening and intracellular antiviral activity of hairpin ribozymes directed against hepatitis B virus. J Virol 1999; 73: 5381-7
-
(1999)
J Virol
, vol.73
, pp. 5381-5387
-
-
Zu Putlitz, J.1
Yu, Q.2
Burke, J.M.3
-
18
-
-
0030743739
-
Intracellular application of hairpin ribozyme genes against hepatitis B virus
-
Welch PJ, Tritz R, Yei S, et al. Intracellular application of hairpin ribozyme genes against hepatitis B virus. Gene Ther 1997; 4: 736-43
-
(1997)
Gene Ther
, vol.4
, pp. 736-743
-
-
Welch, P.J.1
Tritz, R.2
Yei, S.3
-
19
-
-
0028037417
-
Characterization of hepatitis B virus core mutants that inhibit viral replication
-
Scaglioni PP, Melegari M, Wands JR. Characterization of hepatitis B virus core mutants that inhibit viral replication. Virology 1994; 205: 112-20
-
(1994)
Virology
, vol.205
, pp. 112-120
-
-
Scaglioni, P.P.1
Melegari, M.2
Wands, J.R.3
-
20
-
-
0029953004
-
Use of dominant negative mutants of the hepadnaviral core protein as antiviral agents
-
Scaglioni P, Melegari M, Takahashi M, et al. Use of dominant negative mutants of the hepadnaviral core protein as antiviral agents. Hepatology 1996; 24: 1010-7
-
(1996)
Hepatology
, vol.24
, pp. 1010-1017
-
-
Scaglioni, P.1
Melegari, M.2
Takahashi, M.3
-
22
-
-
0033943728
-
Molecular biology of hepatitis C infection
-
Drazan KE. Molecular biology of hepatitis C infection. Liver Transpl 2000; 6: 396-406
-
(2000)
Liver Transpl
, vol.6
, pp. 396-406
-
-
Drazan, K.E.1
-
23
-
-
0036091719
-
Hepatitis C advances in antiviral therapy: What is accepted treatment now?
-
McHutchison JG. Hepatitis C advances in antiviral therapy: what is accepted treatment now? J Gastroenterol Hepatol 2002; 17: 431-41
-
(2002)
J Gastroenterol Hepatol
, vol.17
, pp. 431-441
-
-
McHutchison, J.G.1
-
24
-
-
0035934568
-
Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: A randomised trial
-
Manns MP, McHutchison JG, Gordon SC, et al. Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial. Lancet 2001; 358: 958-65
-
(2001)
Lancet
, vol.358
, pp. 958-965
-
-
Manns, M.P.1
McHutchison, J.G.2
Gordon, S.C.3
-
25
-
-
0028303251
-
Specific inhibition of hepatitis C virus expression by antisense oligodeoxynucleotides: In vitro model for selection of target sequence
-
Wakita T, Wands JR. Specific inhibition of hepatitis C virus expression by antisense oligodeoxynucleotides: in vitro model for selection of target sequence. J Biol Chem 1994; 269: 14205-10
-
(1994)
J Biol Chem
, vol.269
, pp. 14205-14210
-
-
Wakita, T.1
Wands, J.R.2
-
26
-
-
0032932079
-
Antiviral effects of antisense RNA on hepatitis C virus RNA translation and expression
-
Wakita T, Moradpour D, Tokushihge K, et al. Antiviral effects of antisense RNA on hepatitis C virus RNA translation and expression. J Med Virol 1999; 57: 217-22
-
(1999)
J Med Virol
, vol.57
, pp. 217-222
-
-
Wakita, T.1
Moradpour, D.2
Tokushihge, K.3
-
27
-
-
0029972264
-
A potential therapeutic application of hairpin ribozymes: In vitro and in vivo studies of gene therapy for hepatitis C virus infection
-
Welch PJ, Tritz R, Yei S, et al. A potential therapeutic application of hairpin ribozymes: in vitro and in vivo studies of gene therapy for hepatitis C virus infection. Gene Ther 1996; 3: 994-1001
-
(1996)
Gene Ther
, vol.3
, pp. 994-1001
-
-
Welch, P.J.1
Tritz, R.2
Yei, S.3
-
28
-
-
0032527497
-
Ribozyme gene therapy for hepatitis C virus infection
-
Welch PJ, Yei S, Barber JR. Ribozyme gene therapy for hepatitis C virus infection. Clin Diagn Virol 1998; 10: 163-71
-
(1998)
Clin Diagn Virol
, vol.10
, pp. 163-171
-
-
Welch, P.J.1
Yei, S.2
Barber, J.R.3
-
29
-
-
0030481468
-
Intracellular cleavage of hepatitis C virus RNA and inhibition of viral protein translation by hammerhead ribozymes
-
Sakamoto N, Wu CH, Wu GY. Intracellular cleavage of hepatitis C virus RNA and inhibition of viral protein translation by hammerhead ribozymes. J Clin Invest 1996; 98: 2720-8
-
(1996)
J Clin Invest
, vol.98
, pp. 2720-2728
-
-
Sakamoto, N.1
Wu, C.H.2
Wu, G.Y.3
-
30
-
-
17544378561
-
Inhibition of hepatitis C virus (HCV)-RNA-dependent translation and replication of a chimeric HCV poliovirus using synthetic stabilized ribozymes
-
Macejak DG, Jensen KL, Jamison SF, et al. Inhibition of hepatitis C virus (HCV)-RNA-dependent translation and replication of a chimeric HCV poliovirus using synthetic stabilized ribozymes. Hepatology 2000; 31: 769-76
-
(2000)
Hepatology
, vol.31
, pp. 769-776
-
-
Macejak, D.G.1
Jensen, K.L.2
Jamison, S.F.3
-
31
-
-
0035553604
-
Enhanced antiviral effect in cell culture of type 1 interferon and ribozymes targeting HCV RNA
-
Macejak DG, Jensen KL, Pavco PA, et al. Enhanced antiviral effect in cell culture of type 1 interferon and ribozymes targeting HCV RNA. J Viral Hepat 2001; 8: 400-5
-
(2001)
J Viral Hepat
, vol.8
, pp. 400-405
-
-
Macejak, D.G.1
Jensen, K.L.2
Pavco, P.A.3
-
32
-
-
0029970824
-
Elimination of hepatitis C virus RNA in infected human hepatocytes by adenovirus-mediated expression of ribozymes
-
Lieber A, He CY, Polyak SJ, et al. Elimination of hepatitis C virus RNA in infected human hepatocytes by adenovirus-mediated expression of ribozymes. J Virol 1996; 70: 8782-91
-
(1996)
J Virol
, vol.70
, pp. 8782-8791
-
-
Lieber, A.1
He, C.Y.2
Polyak, S.J.3
-
33
-
-
0030021968
-
Intracellular inactivation of the hepatitis B virus by cytotoxic T lymphocytes
-
Guidotti LG, Ishikawa T, Hobbs MV, et al. Intracellular inactivation of the hepatitis B virus by cytotoxic T lymphocytes. Immunity 1996; 4: 25-36
-
(1996)
Immunity
, vol.4
, pp. 25-36
-
-
Guidotti, L.G.1
Ishikawa, T.2
Hobbs, M.V.3
-
34
-
-
0030965103
-
Universal hepatitis B vaccination in Taiwan and the incidence of hepatocellular carcinoma in children
-
Taiwan Childhood Hepatoma Study Group
-
Chang MH, Chen CJ, Lai MS, et al. Universal hepatitis B vaccination in Taiwan and the incidence of hepatocellular carcinoma in children. Taiwan Childhood Hepatoma Study Group. N Engl J Med 1997; 336: 1855-9
-
(1997)
N Engl J Med
, vol.336
, pp. 1855-1859
-
-
Chang, M.H.1
Chen, C.J.2
Lai, M.S.3
-
35
-
-
0030903637
-
Prevention of primary liver cancer by immunization
-
Zuckerman AJ. Prevention of primary liver cancer by immunization. N Engl J Med 1997; 336: 1906-7
-
(1997)
N Engl J Med
, vol.336
, pp. 1906-1907
-
-
Zuckerman, A.J.1
-
36
-
-
0035925668
-
Immunotherapy of chronic hepatitis B by anti HBV vaccine: From present to future
-
Michel ML, Pol S, Brechot C, et al. Immunotherapy of chronic hepatitis B by anti HBV vaccine: from present to future. Vaccine 2001; 19: 2395-9
-
(2001)
Vaccine
, vol.19
, pp. 2395-2399
-
-
Michel, M.L.1
Pol, S.2
Brechot, C.3
-
37
-
-
0029549730
-
Immune responses to hepatitis B virus surface and core antigens in mice, monkeys, and pigs after Accell particle-mediated DNA immunization
-
Fuller JT, Fuller DH, McCabe D, et al. Immune responses to hepatitis B virus surface and core antigens in mice, monkeys, and pigs after Accell particle-mediated DNA immunization. Ann N Y Acad Sci 1995; 772: 282-4
-
(1995)
Ann N Y Acad Sci
, vol.772
, pp. 282-284
-
-
Fuller, J.T.1
Fuller, D.H.2
McCabe, D.3
-
38
-
-
0034666835
-
Multiepitopic HLA-A*0201-restricted immune response against hepatitis B surface antigen after DNA-based immunization
-
Loirat D, Lemonnier FA, Michel ML. Multiepitopic HLA-A*0201-restricted immune response against hepatitis B surface antigen after DNA-based immunization. J Immunol 2000; 165: 4748-55
-
(2000)
J Immunol
, vol.165
, pp. 4748-4755
-
-
Loirat, D.1
Lemonnier, F.A.2
Michel, M.L.3
-
39
-
-
0034880464
-
DNA vaccines for prophylactic or therapeutic immunization against hepatitis B
-
Michel ML, Loirat D. DNA vaccines for prophylactic or therapeutic immunization against hepatitis B. Intervirology 2001; 44: 78-87
-
(2001)
Intervirology
, vol.44
, pp. 78-87
-
-
Michel, M.L.1
Loirat, D.2
-
40
-
-
0029101242
-
Nucleic acid vaccination primes hepatitis B virus surface antigen-specific cytotoxic T lymphocytes in nonresponder mice
-
Schirmbeck R, Bohm W, Ando K, et al. Nucleic acid vaccination primes hepatitis B virus surface antigen-specific cytotoxic T lymphocytes in nonresponder mice. J Virol 1995; 69: 5929-34
-
(1995)
J Virol
, vol.69
, pp. 5929-5934
-
-
Schirmbeck, R.1
Bohm, W.2
Ando, K.3
-
41
-
-
0033120573
-
Utilization of MHC class I transgenic mice for development of minigene DNA vaccines encoding multiple HLA-restricted CTL epitopes
-
Ishioka GY, Fikes J, Hermanson G, et al. Utilization of MHC class I transgenic mice for development of minigene DNA vaccines encoding multiple HLA-restricted CTL epitopes. J Immunol 1999; 162: 3915-25
-
(1999)
J Immunol
, vol.162
, pp. 3915-3925
-
-
Ishioka, G.Y.1
Fikes, J.2
Hermanson, G.3
-
42
-
-
0032518355
-
In vivo induction of specific cytotoxic T lymphocytes in mice and rhesus macaques immunized with DNA vector encoding an HIV epitope fused with hepatitis B surface antigen
-
Le Borgne S, Mancini M, Le Grand R, et al. In vivo induction of specific cytotoxic T lymphocytes in mice and rhesus macaques immunized with DNA vector encoding an HIV epitope fused with hepatitis B surface antigen. Virology 1998; 240: 304-15
-
(1998)
Virology
, vol.240
, pp. 304-315
-
-
Le Borgne, S.1
Mancini, M.2
Le Grand, R.3
-
43
-
-
0032077308
-
Differential cellular and humoral immune responses to HCV core and HBV envelope proteins after genetic immunizations using chimeric constructs
-
Geissler M, Tokushige K, Wakita T, et al. Differential cellular and humoral immune responses to HCV core and HBV envelope proteins after genetic immunizations using chimeric constructs. Vaccine 1998; 16: 857-67
-
(1998)
Vaccine
, vol.16
, pp. 857-867
-
-
Geissler, M.1
Tokushige, K.2
Wakita, T.3
-
44
-
-
0029084640
-
DNA-based immunization with chimeric vectors for the induction of immune responses against the hepatitis C virus nucleocapsid
-
Major ME, Vitvitski L, Mink MA, et al. DNA-based immunization with chimeric vectors for the induction of immune responses against the hepatitis C virus nucleocapsid. J Virol 1995; 69: 5798-805
-
(1995)
J Virol
, vol.69
, pp. 5798-5805
-
-
Major, M.E.1
Vitvitski, L.2
Mink, M.A.3
-
45
-
-
0030239828
-
Induction of NK activity in murine and human cells by CpG motifs in oligodeoxynucleotides and bacterial DNA
-
Ballas ZK, Rasmussen WL, Krieg AM. Induction of NK activity in murine and human cells by CpG motifs in oligodeoxynucleotides and bacterial DNA. J Immunol 1996; 157: 1840-5
-
(1996)
J Immunol
, vol.157
, pp. 1840-1845
-
-
Ballas, Z.K.1
Rasmussen, W.L.2
Krieg, A.M.3
-
46
-
-
0029984358
-
CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma
-
Klinman DM, Yi AK, Beaucage SL, et al. CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma. Proc Natl Acad Sci U S A 1996; 93: 2879-83
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 2879-2883
-
-
Klinman, D.M.1
Yi, A.K.2
Beaucage, S.L.3
-
47
-
-
0034046182
-
DNA vaccines: Immunology, application, and optimization
-
Gurunathan S, Klinman DM, Seder RA. DNA vaccines: immunology, application, and optimization. Annu Rev Immunol 2000; 18: 927-74
-
(2000)
Annu Rev Immunol
, vol.18
, pp. 927-974
-
-
Gurunathan, S.1
Klinman, D.M.2
Seder, R.A.3
-
48
-
-
0033521543
-
DNA vaccination: Transfection and activation of dendritic cells as key events for immunity
-
Akbari O, Panjwani N, Garcia S, et al. DNA vaccination: transfection and activation of dendritic cells as key events for immunity. J Exp Med 1999; 189: 169-78
-
(1999)
J Exp Med
, vol.189
, pp. 169-178
-
-
Akbari, O.1
Panjwani, N.2
Garcia, S.3
-
49
-
-
1842299314
-
Characterization of humoral and CD4+ cellular responses after genetic immunization with retroviral vectors expressing different forms of the hepatitis B virus core and e antigens
-
Sallberg M, Townsend K, Chen M, et al. Characterization of humoral and CD4+ cellular responses after genetic immunization with retroviral vectors expressing different forms of the hepatitis B virus core and e antigens. J Virol 1997; 71: 5295-303
-
(1997)
J Virol
, vol.71
, pp. 5295-5303
-
-
Sallberg, M.1
Townsend, K.2
Chen, M.3
-
50
-
-
0025762458
-
Development of immunogenic recombinant Oka varicella vaccine expressing hepatitis B virus surface antigen
-
Shiraki K, Hayakawa Y, Mori H, et al. Development of immunogenic recombinant Oka varicella vaccine expressing hepatitis B virus surface antigen. J Gen Virol 1991; 72: 1393-9
-
(1991)
J Gen Virol
, vol.72
, pp. 1393-1399
-
-
Shiraki, K.1
Hayakawa, Y.2
Mori, H.3
-
51
-
-
0031834248
-
Use of SV40 to immunize against hepatitis B surface antigen: Implications for the use of SV40 for gene transduction and its use as an immunizing agent
-
Kondo R, Feitelson MA, Strayer DS. Use of SV40 to immunize against hepatitis B surface antigen: implications for the use of SV40 for gene transduction and its use as an immunizing agent. Gene Ther 1998; 5: 575-82
-
(1998)
Gene Ther
, vol.5
, pp. 575-582
-
-
Kondo, R.1
Feitelson, M.A.2
Strayer, D.S.3
-
52
-
-
0033605350
-
DNA-mediated immunization to hepatitis B virus envelope proteins: preS antigen secretion enhances the humoral response
-
Prange R, Werr M. DNA-mediated immunization to hepatitis B virus envelope proteins: preS antigen secretion enhances the humoral response. Vaccine 1999; 17: 617-23
-
(1999)
Vaccine
, vol.17
, pp. 617-623
-
-
Prange, R.1
Werr, M.2
-
54
-
-
0033868504
-
Vaccine development for hepatitis C
-
Lechmann M, Liang TJ. Vaccine development for hepatitis C. Semin Liver Dis 2000; 20: 211-26
-
(2000)
Semin Liver Dis
, vol.20
, pp. 211-226
-
-
Lechmann, M.1
Liang, T.J.2
-
55
-
-
17544368390
-
Evaluation of hepatitis C virus glycoprotein E2 for vaccine design: An endoplasmic reticulum-retained recombinant protein is superior to secreted recombinant protein and DNA-based vaccine candidates
-
Heile JM, Fong YL, Rosa D, et al. Evaluation of hepatitis C virus glycoprotein E2 for vaccine design: an endoplasmic reticulum-retained recombinant protein is superior to secreted recombinant protein and DNA-based vaccine candidates. J Virol 2000; 74: 6885-92
-
(2000)
J Virol
, vol.74
, pp. 6885-6892
-
-
Heile, J.M.1
Fong, Y.L.2
Rosa, D.3
-
56
-
-
0034466814
-
Enhancing B- and T-cell immune response to a hepatitis C virus E2 DNA vaccine by intramuscular electrical gene transfer
-
Zucchelli S, Capone S, Fattori E, et al. Enhancing B- and T-cell immune response to a hepatitis C virus E2 DNA vaccine by intramuscular electrical gene transfer. J Virol 2000; 74: 11598-607
-
(2000)
J Virol
, vol.74
, pp. 11598-11607
-
-
Zucchelli, S.1
Capone, S.2
Fattori, E.3
-
57
-
-
0033848911
-
Vaccination of chimpanzees with plasmid DNA encoding the hepatitis C virus (HCV) envelope E2 protein modified the infection after challenge with homologous monoclonal HCV
-
Forns X, Payette PJ, Ma X, et al. Vaccination of chimpanzees with plasmid DNA encoding the hepatitis C virus (HCV) envelope E2 protein modified the infection after challenge with homologous monoclonal HCV. Hepatology 2000; 32: 618-25
-
(2000)
Hepatology
, vol.32
, pp. 618-625
-
-
Forns, X.1
Payette, P.J.2
Ma, X.3
-
58
-
-
0028038280
-
Sequence analysis of the core gene of 14 hepatitis C virus genotypes
-
Bukh J, Purcell RH, Miller RH. Sequence analysis of the core gene of 14 hepatitis C virus genotypes. Proc Natl Acad Sci U S A 1994; 91: 8239-43
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 8239-8243
-
-
Bukh, J.1
Purcell, R.H.2
Miller, R.H.3
-
59
-
-
0032870465
-
Immune selection and genetic sequence variation in core and envelope regions of hepatitis C virus
-
Christie JM, Chapel H, Chapman RW, et al. Immune selection and genetic sequence variation in core and envelope regions of hepatitis C virus. Hepatology 1999; 30: 1037-44
-
(1999)
Hepatology
, vol.30
, pp. 1037-1044
-
-
Christie, J.M.1
Chapel, H.2
Chapman, R.W.3
-
60
-
-
0029971032
-
Expression and immune response to hepatitis C virus core DNA-based vaccine constructs
-
Tokushige K, Wakita T, Pachuk C, et al. Expression and immune response to hepatitis C virus core DNA-based vaccine constructs. Hepatology 1996; 24: 14-20
-
(1996)
Hepatology
, vol.24
, pp. 14-20
-
-
Tokushige, K.1
Wakita, T.2
Pachuk, C.3
-
61
-
-
0034053296
-
Properties of the hepatitis C virus core protein: A structural protein that modulates cellular processes
-
McLauchlan J. Properties of the hepatitis C virus core protein: a structural protein that modulates cellular processes. J Viral Hepat 2000; 7: 2-14
-
(2000)
J Viral Hepat
, vol.7
, pp. 2-14
-
-
McLauchlan, J.1
-
62
-
-
0035284757
-
Characterization of hepatitis C virus core-specific immune responses primed in rhesus macaques by a nonclassical ISCOM vaccine
-
Polakos NK, Drane D, Cox J, et al. Characterization of hepatitis C virus core-specific immune responses primed in rhesus macaques by a nonclassical ISCOM vaccine. J Immunol 2001; 166: 3589-98
-
(2001)
J Immunol
, vol.166
, pp. 3589-3598
-
-
Polakos, N.K.1
Drane, D.2
Cox, J.3
-
63
-
-
0032212215
-
Genetic immunization generates cellular and humoral immune responses against the nonstructural proteins of the hepatitis C virus in a murine model
-
Encke J, zu Putlitz J, Geissler M, et al. Genetic immunization generates cellular and humoral immune responses against the nonstructural proteins of the hepatitis C virus in a murine model. J Immunol 1998; 161: 4917-23
-
(1998)
J Immunol
, vol.161
, pp. 4917-4923
-
-
Encke, J.1
Zu Putlitz, J.2
Geissler, M.3
-
64
-
-
0035192083
-
Different hepatitis C virus nonstructural protein 3 (Ns3)-DNA-expressing vaccines induce in HLA-A2.1 transgenic mice stable cytotoxic T lymphocytes that target one major epitope
-
Brinster C, Muguet S, Lone YC, et al. Different hepatitis C virus nonstructural protein 3 (Ns3)-DNA- expressing vaccines induce in HLA-A2.1 transgenic mice stable cytotoxic T lymphocytes that target one major epitope. Hepatology 2001; 34: 1206-17
-
(2001)
Hepatology
, vol.34
, pp. 1206-1217
-
-
Brinster, C.1
Muguet, S.2
Lone, Y.C.3
-
65
-
-
0034766336
-
Oral immunization with HCV-NS3-transformed Salmonella: Induction of HCV- specific CTL in a transgenic mouse model
-
Wedemeyer H, Gagneten S, Davis A, et al. Oral immunization with HCV-NS3-transformed Salmonella: induction of HCV- specific CTL in a transgenic mouse model. Gastroenterology 2001; 121: 1158-66
-
(2001)
Gastroenterology
, vol.121
, pp. 1158-1166
-
-
Wedemeyer, H.1
Gagneten, S.2
Davis, A.3
-
66
-
-
0035202920
-
Genetic immunization of wild-type and hepatitis C virus transgenic mice reveals a hierarchy of cellular immune response and tolerance induction against hepatitis C virus structural proteins
-
Satoi J, Murata K, Lechmann M, et al. Genetic immunization of wild-type and hepatitis C virus transgenic mice reveals a hierarchy of cellular immune response and tolerance induction against hepatitis C virus structural proteins. J Virol 2001; 75: 12121-7
-
(2001)
J Virol
, vol.75
, pp. 12121-12127
-
-
Satoi, J.1
Murata, K.2
Lechmann, M.3
-
67
-
-
0034531322
-
Development of a plant-derived subunit vaccine candidate against hepatitis C virus
-
Nemchinov LG, Liang TJ, Rifaat MM, et al. Development of a plant-derived subunit vaccine candidate against hepatitis C virus. Arch Virol 2000; 145: 2557-73
-
(2000)
Arch Virol
, vol.145
, pp. 2557-2573
-
-
Nemchinov, L.G.1
Liang, T.J.2
Rifaat, M.M.3
-
68
-
-
0029461123
-
Targeted delivery of antisense DNA in woodchuck hepatitis virus-infected woodchucks
-
Bartholomew RM, Carmichael EP, Findeis MA, et al. Targeted delivery of antisense DNA in woodchuck hepatitis virus-infected woodchucks. J Viral Hepat 1995; 2: 273-8
-
(1995)
J Viral Hepat
, vol.2
, pp. 273-278
-
-
Bartholomew, R.M.1
Carmichael, E.P.2
Findeis, M.A.3
-
69
-
-
0032945030
-
Hepatocyte-directed gene delivery by receptor-mediated endocytosis
-
Smith RM, Wu GY. Hepatocyte-directed gene delivery by receptor-mediated endocytosis. Semin Liver Dis 1999; 19: 83-92
-
(1999)
Semin Liver Dis
, vol.19
, pp. 83-92
-
-
Smith, R.M.1
Wu, G.Y.2
-
70
-
-
0030662074
-
Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells
-
Ivics Z, Hackett PB, Plasterk RH, et al. Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells. Cell 1997; 91: 501-10
-
(1997)
Cell
, vol.91
, pp. 501-510
-
-
Ivics, Z.1
Hackett, P.B.2
Plasterk, R.H.3
-
71
-
-
0034103009
-
Somatic integration and long-term transgene expression in normal and haemophilic mice using a DNA transposon system
-
Yant SR, Meuse L, Chiu W, et al. Somatic integration and long-term transgene expression in normal and haemophilic mice using a DNA transposon system. Nat Genet 2000; 25: 35-41
-
(2000)
Nat Genet
, vol.25
, pp. 35-41
-
-
Yant, S.R.1
Meuse, L.2
Chiu, W.3
-
72
-
-
0003109621
-
Targeted inhibition of hepatitis B virus gene expression: A gene therapy approach
-
Tung FYT, Bowen SW. Targeted inhibition of hepatitis B virus gene expression: a gene therapy approach. Front Biosci 1998; 3: a11-5
-
(1998)
Front Biosci
, vol.3
-
-
Tung, F.Y.T.1
Bowen, S.W.2
-
73
-
-
0032925803
-
Retroviral vectors for liver-directed gene therapy
-
Kalpana GV. Retroviral vectors for liver-directed gene therapy. Semin Liver Dis 1999; 19: 27-37
-
(1999)
Semin Liver Dis
, vol.19
, pp. 27-37
-
-
Kalpana, G.V.1
-
74
-
-
0033616680
-
Sustained correction of bleeding disorder in hemophilia B mice by gene therapy
-
Wang L, Takabe K, Bidlingmaier SM, et al. Sustained correction of bleeding disorder in hemophilia B mice by gene therapy. Proc Natl Acad Sci U S A 1999; 96: 3906-10
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 3906-3910
-
-
Wang, L.1
Takabe, K.2
Bidlingmaier, S.M.3
-
75
-
-
0033735275
-
SV40-based gene therapy vectors: Turning an adversary into a friend
-
Strayer DS. SV40-based gene therapy vectors: turning an adversary into a friend. Curr Opin Mol Ther 2000; 2: 570-8
-
(2000)
Curr Opin Mol Ther
, vol.2
, pp. 570-578
-
-
Strayer, D.S.1
-
76
-
-
0032942075
-
Gene delivery to the liver using simian virus 40-derived vectors
-
Strayer DS, Zern MA. Gene delivery to the liver using simian virus 40-derived vectors. Semin Liver Dis 1999; 19: 71-81
-
(1999)
Semin Liver Dis
, vol.19
, pp. 71-81
-
-
Strayer, D.S.1
Zern, M.A.2
-
77
-
-
0032948552
-
Adenovirus-mediated gene therapy of liver diseases
-
Ilan Y, Saito H, Thummala NR, et al. Adenovirus-mediated gene therapy of liver diseases. Semin Liver Dis 1999; 19: 49-59
-
(1999)
Semin Liver Dis
, vol.19
, pp. 49-59
-
-
Ilan, Y.1
Saito, H.2
Thummala, N.R.3
-
78
-
-
0031778879
-
Role of E4 in eliciting CD4 T-cell and B-cell responses to adenovirus vectors delivered to murine and nonhuman primate lungs
-
Chirmule N, Hughes JV, Gao GP, et al. Role of E4 in eliciting CD4 T-cell and B-cell responses to adenovirus vectors delivered to murine and nonhuman primate lungs. J Virol 1998; 72: 6138-45
-
(1998)
J Virol
, vol.72
, pp. 6138-6145
-
-
Chirmule, N.1
Hughes, J.V.2
Gao, G.P.3
-
79
-
-
0032530110
-
Cellular immune response to adenoviral vector infected cells does not require de novo viral gene expression: Implications for gene therapy
-
Kafri T, Morgan D, Krahl T, et al. Cellular immune response to adenoviral vector infected cells does not require de novo viral gene expression: implications for gene therapy. Proc Natl Acad Sci U S A 1998; 95: 11377-82
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 11377-11382
-
-
Kafri, T.1
Morgan, D.2
Krahl, T.3
-
80
-
-
0036052121
-
A non-immunogenic adenoviral vector, coexpressing CTLA4Ig and bilirubin-uridine-diphosphoglucuronateglucuronosyltransferase permits long-term, repeatable transgene expression in the Gunn rat model of Crigler-Najjar syndrome
-
Thummala NR, Ghosh SS, Lee SW, et al. A non-immunogenic adenoviral vector, coexpressing CTLA4Ig and bilirubin-uridine-diphosphoglucuronateglucuronosyltransferase permits long-term, repeatable transgene expression in the Gunn rat model of Crigler-Najjar syndrome. Gene Ther 2002; 9: 981-90
-
(2002)
Gene Ther
, vol.9
, pp. 981-990
-
-
Thummala, N.R.1
Ghosh, S.S.2
Lee, S.W.3
-
81
-
-
0030775646
-
Stable in vivo gene transduction via a novel adenoviral/retroviral chimeric vector
-
Feng M, Jackson Jr WH, Goldman CK, et al. Stable in vivo gene transduction via a novel adenoviral/retroviral chimeric vector. Nat Biotechnol 1997; 15: 866-70
-
(1997)
Nat Biotechnol
, vol.15
, pp. 866-870
-
-
Feng, M.1
Jackson W.H., Jr.2
Goldman, C.K.3
-
82
-
-
0033057474
-
Site-specific integration mediated by a hybrid adenovirus/adeno-associated virus vector
-
Recchia A, Parks RJ, Lamartina S, et al. Site-specific integration mediated by a hybrid adenovirus/adeno-associated virus vector. Proc Natl Acad Sci U S A 1999; 96: 2615-20
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 2615-2620
-
-
Recchia, A.1
Parks, R.J.2
Lamartina, S.3
-
83
-
-
0030280036
-
The potential of extrachromosomal replicating vectors for gene therapy
-
Calos MP. The potential of extrachromosomal replicating vectors for gene therapy. Trends Genet 1996; 12: 463-6
-
(1996)
Trends Genet
, vol.12
, pp. 463-466
-
-
Calos, M.P.1
-
84
-
-
0034168963
-
Stable transduction of actively dividing cells via a novel adenoviral/episomal vector
-
Leblois L, Roche C, Di Falco ND, et al. Stable transduction of actively dividing cells via a novel adenoviral/episomal vector. Mol Ther 2000; 1: 314-22
-
(2000)
Mol Ther
, vol.1
, pp. 314-322
-
-
Leblois, L.1
Roche, C.2
Di Falco, N.D.3
|