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Volumn 19, Issue 1, 1999, Pages 83-92

Hepatocyte-directed gene delivery by receptor-mediated endocytosis

Author keywords

Gene therapy; Liposomes; Receptor mediated endocytosis

Indexed keywords

ALPHA 1 ANTITRYPSIN; ASIALOGLYCOPROTEIN RECEPTOR; CHOLESTEROL; LIPOSOME; LOW DENSITY LIPOPROTEIN RECEPTOR; ORNITHINE CARBAMOYLTRANSFERASE;

EID: 0032945030     PISSN: 02728087     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-1007100     Document Type: Review
Times cited : (31)

References (107)
  • 2
    • 0028834831 scopus 로고
    • Gene therapy for human liver disease
    • Raper SE, Wilson JM. Gene therapy for human liver disease. Prog Liver Dis 1995;13:201-230
    • (1995) Prog Liver Dis , vol.13 , pp. 201-230
    • Raper, S.E.1    Wilson, J.M.2
  • 3
    • 0029116596 scopus 로고
    • Prospects of therapy of liver diseases with foreign genes
    • Kormis KK, Wu GY. Prospects of therapy of liver diseases with foreign genes. Semin Liver Dis 1995;15:257-267
    • (1995) Semin Liver Dis , vol.15 , pp. 257-267
    • Kormis, K.K.1    Wu, G.Y.2
  • 4
    • 0028793489 scopus 로고
    • A pilot study of ex vivo gene therapy for homozygous familial hypercholesterolemia
    • Grossman M, Rader DJ, Muller DW, et al. A pilot study of ex vivo gene therapy for homozygous familial hypercholesterolemia. Nat Med 1995;1:1148-1154
    • (1995) Nat Med , vol.1 , pp. 1148-1154
    • Grossman, M.1    Rader, D.J.2    Muller, D.W.3
  • 5
    • 0029557063 scopus 로고
    • Liver-directed gene therapy: Molecular tools and current preclinical and clinical studies
    • Alt M, Caselmann WH. Liver-directed gene therapy: Molecular tools and current preclinical and clinical studies. J Hepatol 1995;23:746-758
    • (1995) J Hepatol , vol.23 , pp. 746-758
    • Alt, M.1    Caselmann, W.H.2
  • 6
    • 0028350767 scopus 로고
    • Gene therapy: Applications to the treatment of gastrointestinal and liver diseases
    • Chang AG, Wu GY. Gene therapy: Applications to the treatment of gastrointestinal and liver diseases. Gastroenterology 1994; 106:1076-1084
    • (1994) Gastroenterology , vol.106 , pp. 1076-1084
    • Chang, A.G.1    Wu, G.Y.2
  • 7
    • 0030009774 scopus 로고    scopus 로고
    • Liver-directed gene transfer and application to therapy
    • Sandig V, Strauss M. Liver-directed gene transfer and application to therapy. J Mol Med 1996;74:205-212
    • (1996) J Mol Med , vol.74 , pp. 205-212
    • Sandig, V.1    Strauss, M.2
  • 8
    • 0028946357 scopus 로고
    • Targeted vectors for gene therapy
    • Miller N, Vile R. Targeted vectors for gene therapy. FASEB J 1995;9:190-199
    • (1995) FASEB J , vol.9 , pp. 190-199
    • Miller, N.1    Vile, R.2
  • 10
    • 0030922565 scopus 로고    scopus 로고
    • Adenoviral vectors for hepatic gene transfer in animals
    • Kay MA. Adenoviral vectors for hepatic gene transfer in animals. Chest 1997;111:138S-142S
    • (1997) Chest , vol.111
    • Kay, M.A.1
  • 11
    • 0029973447 scopus 로고    scopus 로고
    • Adenovirus-mediated gene transfer: Strategies and applications in lipoprotein research
    • Gerard RD, Chan L. Adenovirus-mediated gene transfer: Strategies and applications in lipoprotein research. Curr Opin Lipidol 1996;7:105-111
    • (1996) Curr Opin Lipidol , vol.7 , pp. 105-111
    • Gerard, R.D.1    Chan, L.2
  • 12
    • 0030890713 scopus 로고    scopus 로고
    • Nonviral vectors for in vivo gene delivery: Physicochemical and pharmacokinetic considerations
    • Mahato RI, Takakura Y, Hashida M. Nonviral vectors for in vivo gene delivery: Physicochemical and pharmacokinetic considerations. Crit Rev Ther Drug Carrier Syst 1997;14:133-172
    • (1997) Crit Rev Ther Drug Carrier Syst , vol.14 , pp. 133-172
    • Mahato, R.I.1    Takakura, Y.2    Hashida, M.3
  • 13
    • 0029147628 scopus 로고
    • Nonviral gene therapy: The promise of genes as pharmaceutical products
    • Ledley FD. Nonviral gene therapy: The promise of genes as pharmaceutical products. Hum Gene Ther 1995;6:1129-1144
    • (1995) Hum Gene Ther , vol.6 , pp. 1129-1144
    • Ledley, F.D.1
  • 14
    • 0030175548 scopus 로고    scopus 로고
    • Modification of liposomes for liver targeting
    • Wu J, Zern MA. Modification of liposomes for liver targeting. J Hepatol 1996;24:757-763
    • (1996) J Hepatol , vol.24 , pp. 757-763
    • Wu, J.1    Zern, M.A.2
  • 15
    • 0028917042 scopus 로고
    • Receptor-mediated DNA delivery approaches to human gene therapy
    • Phillips SC. Receptor-mediated DNA delivery approaches to human gene therapy. Biologicals 1995;23:13-16
    • (1995) Biologicals , vol.23 , pp. 13-16
    • Phillips, S.C.1
  • 16
    • 0030996011 scopus 로고    scopus 로고
    • Progress in transcriptionally targeted and regulatable vectors for genetic therapy
    • Miller N, Whelan J. Progress in transcriptionally targeted and regulatable vectors for genetic therapy. Hum Gene Ther 1997;8: 803-815
    • (1997) Hum Gene Ther , vol.8 , pp. 803-815
    • Miller, N.1    Whelan, J.2
  • 17
    • 0030806214 scopus 로고    scopus 로고
    • Targeted delivery of peptides, proteins, and genes by receptor-mediated endocytosis
    • Kato Y, Sugiyama Y. Targeted delivery of peptides, proteins, and genes by receptor-mediated endocytosis. Crit Rev Ther Drug Carrier Syst 1997;14:287-331
    • (1997) Crit Rev Ther Drug Carrier Syst , vol.14 , pp. 287-331
    • Kato, Y.1    Sugiyama, Y.2
  • 18
    • 0029687654 scopus 로고    scopus 로고
    • Strategies to accomplish gene delivery via the receptor-mediated endocytosis pathway
    • Cristiano RJ, Curiel DT. Strategies to accomplish gene delivery via the receptor-mediated endocytosis pathway. Cancer Gene Ther 1996;3:49-57
    • (1996) Cancer Gene Ther , vol.3 , pp. 49-57
    • Cristiano, R.J.1    Curiel, D.T.2
  • 20
    • 0028803615 scopus 로고
    • Receptor cell biology: Receptor-mediated endocytosis
    • Schwartz AL. Receptor cell biology: Receptor-mediated endocytosis. Pediatr Res 1995;38:835-843
    • (1995) Pediatr Res , vol.38 , pp. 835-843
    • Schwartz, A.L.1
  • 21
    • 0030661590 scopus 로고    scopus 로고
    • Hepatic uptake of chylomicron remnants
    • Cooper AD. Hepatic uptake of chylomicron remnants. J Lipid Res 1997;38:2173-2192
    • (1997) J Lipid Res , vol.38 , pp. 2173-2192
    • Cooper, A.D.1
  • 22
    • 0028998769 scopus 로고
    • The asialoglycoprotein receptor: Relationships between structure, function, and expression
    • Stockert RJ. The asialoglycoprotein receptor: Relationships between structure, function, and expression. Physiol Rev 1995;75: 591-609
    • (1995) Physiol Rev , vol.75 , pp. 591-609
    • Stockert, R.J.1
  • 23
    • 0027417057 scopus 로고
    • Hepatic and intrahepatic targeting of an anti-inflammatory agent with human serum albumin and neoglycoproteins as carrier molecules
    • Franssen EJ, Jansen RW, Vaalburg M, Meijer DK. Hepatic and intrahepatic targeting of an anti-inflammatory agent with human serum albumin and neoglycoproteins as carrier molecules. Biochem Pharmacol 1993;45:1215-1226
    • (1993) Biochem Pharmacol , vol.45 , pp. 1215-1226
    • Franssen, E.J.1    Jansen, R.W.2    Vaalburg, M.3    Meijer, D.K.4
  • 24
    • 0027185699 scopus 로고
    • Synthesis and pharmacokinetics of a new liver-specific carrier, glycosylated carboxymethyl-dextran, and its application to drug targeting
    • Nishikawa M, Kamijo A, Fujita T, Takakura Y, Sezaki H, Hashida M. Synthesis and pharmacokinetics of a new liver-specific carrier, glycosylated carboxymethyl-dextran, and its application to drug targeting. Pharm Res 1993;10:1253-1261
    • (1993) Pharm Res , vol.10 , pp. 1253-1261
    • Nishikawa, M.1    Kamijo, A.2    Fujita, T.3    Takakura, Y.4    Sezaki, H.5    Hashida, M.6
  • 26
    • 0029019120 scopus 로고
    • Fusion of cationic liposomes with mammalian cells occurs after endocytosis
    • Wrobel I, Collins D. Fusion of cationic liposomes with mammalian cells occurs after endocytosis. Biochim Biophys Acta 1995;1235:296-304
    • (1995) Biochim Biophys Acta , vol.1235 , pp. 296-304
    • Wrobel, I.1    Collins, D.2
  • 27
    • 0031581171 scopus 로고    scopus 로고
    • Development and characterization of cationic liposomes conjugated with HJV (Sendai virus): Reciprocal effect of cationic lipid for in vitro and in vivo gene transfer
    • Saeki Y, Matsumoto N, Nakano Y, Mori M, Awai K, Kaneda Y. Development and characterization of cationic liposomes conjugated with HJV (Sendai virus): Reciprocal effect of cationic lipid for in vitro and in vivo gene transfer. Hum Gene Ther 1997;8: 2133-2141
    • (1997) Hum Gene Ther , vol.8 , pp. 2133-2141
    • Saeki, Y.1    Matsumoto, N.2    Nakano, Y.3    Mori, M.4    Awai, K.5    Kaneda, Y.6
  • 28
    • 0030032075 scopus 로고    scopus 로고
    • Effects of fusogenic and DNA-binding amphiphilic compounds on the receptor-mediated gene transfer into hepatic cells by asialofetuin-labeled liposomes
    • Hara T, Kuwasawa H, Aramaki Y, et al. Effects of fusogenic and DNA-binding amphiphilic compounds on the receptor-mediated gene transfer into hepatic cells by asialofetuin-labeled liposomes. Biochim Biophys Acta 1996;1278:51-58
    • (1996) Biochim Biophys Acta , vol.1278 , pp. 51-58
    • Hara, T.1    Kuwasawa, H.2    Aramaki, Y.3
  • 29
    • 0029792310 scopus 로고    scopus 로고
    • Receptor-mediated delivery of hepatitis B virus DNA and antisense oligodeoxynucleotides to avian liver cells
    • Madon J, Blum HE. Receptor-mediated delivery of hepatitis B virus DNA and antisense oligodeoxynucleotides to avian liver cells. Hepatology 1996;24:474-481
    • (1996) Hepatology , vol.24 , pp. 474-481
    • Madon, J.1    Blum, H.E.2
  • 30
    • 0028309752 scopus 로고
    • Incorporation of adenovirus into a ligand-based DNA carrier system results in retention ot original receptor specificity and enhances targeted gene expression
    • Wu G, Zhan P, Sze LL, Rosenberg AR, Wu CH. Incorporation of adenovirus into a ligand-based DNA carrier system results in retention ot original receptor specificity and enhances targeted gene expression. J Biol Chem 1994;269:11542-11546
    • (1994) J Biol Chem , vol.269 , pp. 11542-11546
    • Wu, G.1    Zhan, P.2    Sze, L.L.3    Rosenberg, A.R.4    Wu, C.H.5
  • 32
    • 0030050983 scopus 로고    scopus 로고
    • Microtubular disruption prolongs the expression of human bilirubin-uridinediphosphoglucuronate-glucuronosyltransferase-1 gene transferred into Gunn rat livers
    • Chowdhury NR, Hays RM, Bommineni VR, et al. Microtubular disruption prolongs the expression of human bilirubin-uridinediphosphoglucuronate-glucuronosyltransferase-1 gene transferred into Gunn rat livers. J Biol Chem 1996;271:2341-2346
    • (1996) J Biol Chem , vol.271 , pp. 2341-2346
    • Chowdhury, N.R.1    Hays, R.M.2    Bommineni, V.R.3
  • 33
    • 0027997611 scopus 로고
    • Depolymerization of hepatocellular microtubules after partial hepatectomy
    • Bommineni VR, Chowdhury NR, Wu GY, et al. Depolymerization of hepatocellular microtubules after partial hepatectomy. J Biol Chem 1994;269:25200-25205
    • (1994) J Biol Chem , vol.269 , pp. 25200-25205
    • Bommineni, V.R.1    Chowdhury, N.R.2    Wu, G.Y.3
  • 34
    • 0027233696 scopus 로고
    • Fate of DNA targeted to the liver by asialoglycoprotein receptor-mediated endocytosis in vivo. Prolonged persistence in cytoplasmic vesicles after partial hepatectomy
    • Chowdhury NR, Wu CH, Wu GY, Yerneni PC, Bommineni VR, Chowdhury JR. Fate of DNA targeted to the liver by asialoglycoprotein receptor-mediated endocytosis in vivo. Prolonged persistence in cytoplasmic vesicles after partial hepatectomy. J Biol Chem 1993;268:11265-11271
    • (1993) J Biol Chem , vol.268 , pp. 11265-11271
    • Chowdhury, N.R.1    Wu, C.H.2    Wu, G.Y.3    Yerneni, P.C.4    Bommineni, V.R.5    Chowdhury, J.R.6
  • 35
    • 0026722109 scopus 로고
    • A novel mechanism for achieving transgene persistence in vivo after somatic gene transfer into hepatocytes
    • Wilson JM, Grossman M, Cabrera JA, Wu CH, Wu GY. A novel mechanism for achieving transgene persistence in vivo after somatic gene transfer into hepatocytes. J Biol Chem 1992;267: 11483-11489
    • (1992) J Biol Chem , vol.267 , pp. 11483-11489
    • Wilson, J.M.1    Grossman, M.2    Cabrera, J.A.3    Wu, C.H.4    Wu, G.Y.5
  • 36
    • 16944364248 scopus 로고    scopus 로고
    • Highly efficient retrovirus-mediated gene transfer into rat hepatocytes in vivo
    • Kitten O, Cosset FL, Ferry N. Highly efficient retrovirus-mediated gene transfer into rat hepatocytes in vivo. Hum Gene Ther 1997;8:1491-1494
    • (1997) Hum Gene Ther , vol.8 , pp. 1491-1494
    • Kitten, O.1    Cosset, F.L.2    Ferry, N.3
  • 38
    • 0029822002 scopus 로고    scopus 로고
    • Adenovirus-mediated hepatic gene transfer in mice: Comparison of intravascular and biliary administration
    • Peeters MJ, Patijn GA, Lieber A, Meuse L, Kay MA. Adenovirus-mediated hepatic gene transfer in mice: Comparison of intravascular and biliary administration. Hum Gene Ther 1996; 7:1693-1699
    • (1996) Hum Gene Ther , vol.7 , pp. 1693-1699
    • Peeters, M.J.1    Patijn, G.A.2    Lieber, A.3    Meuse, L.4    Kay, M.A.5
  • 39
    • 0029961248 scopus 로고    scopus 로고
    • HBV-derived promoters direct liver-specific expression of an adenovirally transduced LDL receptor gene
    • Sandig V, Loser P, Lieber A, Kay MA, Strauss M. HBV-derived promoters direct liver-specific expression of an adenovirally transduced LDL receptor gene. Gene Ther 1996;3:1002-1009
    • (1996) Gene Ther , vol.3 , pp. 1002-1009
    • Sandig, V.1    Loser, P.2    Lieber, A.3    Kay, M.A.4    Strauss, M.5
  • 40
    • 0031913203 scopus 로고    scopus 로고
    • Characterization of an adenovirus vector containing a heterologous peptide epitope in the HI loop of the fiber knob
    • Krasnykh V, Dmitriev I, Mikheeva G, Miller CR, Belousova N, Curiel DT. Characterization of an adenovirus vector containing a heterologous peptide epitope in the HI loop of the fiber knob. J Virol 1998;72:1844-1852
    • (1998) J Virol , vol.72 , pp. 1844-1852
    • Krasnykh, V.1    Dmitriev, I.2    Mikheeva, G.3    Miller, C.R.4    Belousova, N.5    Curiel, D.T.6
  • 41
    • 0030768124 scopus 로고    scopus 로고
    • Increased in vitro and in vivo gene transfer by adenovirus vectors containing chimeric fiber proteins
    • Wickham TJ, Tzeng E, Shears LL 2nd. et al. Increased in vitro and in vivo gene transfer by adenovirus vectors containing chimeric fiber proteins. J Virol 1997;71:8221-8229
    • (1997) J Virol , vol.71 , pp. 8221-8229
    • Wickham, T.J.1    Tzeng, E.2    Shears L.L. II3
  • 42
    • 0031000327 scopus 로고    scopus 로고
    • Selective targeting of human cells by a chimeric adenovirus vector containing a modified fiber protein
    • Stevenson SC, Rollence M, Marshall-Neff J, McClelland A. Selective targeting of human cells by a chimeric adenovirus vector containing a modified fiber protein. J Virol 1997;71:4782-4790
    • (1997) J Virol , vol.71 , pp. 4782-4790
    • Stevenson, S.C.1    Rollence, M.2    Marshall-Neff, J.3    McClelland, A.4
  • 43
    • 0029793812 scopus 로고    scopus 로고
    • Generation of recombinant adenovirus vectors with modified fibers for altering viral tropism
    • Krasnykh VN, Mikheeva GV, Douglas JT, Curiel DT. Generation of recombinant adenovirus vectors with modified fibers for altering viral tropism. J Virol 1996;70:6839-6846
    • (1996) J Virol , vol.70 , pp. 6839-6846
    • Krasnykh, V.N.1    Mikheeva, G.V.2    Douglas, J.T.3    Curiel, D.T.4
  • 44
    • 0029586317 scopus 로고
    • Targeting of adenovirus penton base to new receptors through replacement of its RGD motif with other receptor-specific peptide motifs
    • Wickham TJ, Carrion ME, Kovesdi I. Targeting of adenovirus penton base to new receptors through replacement of its RGD motif with other receptor-specific peptide motifs. Gene Ther 1995;2:750-756
    • (1995) Gene Ther , vol.2 , pp. 750-756
    • Wickham, T.J.1    Carrion, M.E.2    Kovesdi, I.3
  • 46
    • 0030831076 scopus 로고    scopus 로고
    • The adenohody approach to viral targeting: Specific and enhanced adenoviral gene delivery
    • Watkins SJ, Mesyanzhinov VV, Kurochkina LP, Hawkins RE. The adenohody approach to viral targeting: Specific and enhanced adenoviral gene delivery. Gene Ther 1997;4:1004-1012
    • (1997) Gene Ther , vol.4 , pp. 1004-1012
    • Watkins, S.J.1    Mesyanzhinov, V.V.2    Kurochkina, L.P.3    Hawkins, R.E.4
  • 47
    • 0029794681 scopus 로고    scopus 로고
    • Targeted adenovirus gene transfer to endothelial and smooth muscle cells by using bispecific antibodies
    • Wickham TJ, Segal DM, Reolvink PW, et al. Targeted adenovirus gene transfer to endothelial and smooth muscle cells by using bispecific antibodies. J Virol 1996;70:6831-6838
    • (1996) J Virol , vol.70 , pp. 6831-6838
    • Wickham, T.J.1    Segal, D.M.2    Reolvink, P.W.3
  • 48
    • 0031973035 scopus 로고    scopus 로고
    • Long-term reduction of serum bilirubin levels in Gunn rats by retroviral gene transfer in vivo
    • Tada K, Chowdhury NR, Neufeld D, et al. Long-term reduction of serum bilirubin levels in Gunn rats by retroviral gene transfer in vivo. Liver Transplant Surg 1998;4:78-88
    • (1998) Liver Transplant Surg , vol.4 , pp. 78-88
    • Tada, K.1    Chowdhury, N.R.2    Neufeld, D.3
  • 49
    • 0030008178 scopus 로고    scopus 로고
    • Liver-directed gene therapy: A retroviral vector with a complete LTR and the ApoE enhancer-alpha 1-antitrypsin promoter dramatically increases expression of human alpha 1-antitrypsin in vivo
    • Okuyama T, Huber RM, Bowling W, et al. Liver-directed gene therapy: A retroviral vector with a complete LTR and the ApoE enhancer-alpha 1-antitrypsin promoter dramatically increases expression of human alpha 1-antitrypsin in vivo. Hum Gene Ther 1996;7:637-645
    • (1996) Hum Gene Ther , vol.7 , pp. 637-645
    • Okuyama, T.1    Huber, R.M.2    Bowling, W.3
  • 50
    • 0029800824 scopus 로고    scopus 로고
    • In vivo retroviral-mediated transfer of a marker-gene in ornithine transcarbamylase-deficient Spf(ash) mice
    • Povedin G, Ferry N, Calise D, Revillion Y. In vivo retroviral-mediated transfer of a marker-gene in ornithine transcarbamylase-deficient Spf(ash) mice. J Pediatr Surg 1996;31:1516-1519
    • (1996) J Pediatr Surg , vol.31 , pp. 1516-1519
    • Povedin, G.1    Ferry, N.2    Calise, D.3    Revillion, Y.4
  • 51
    • 0032080179 scopus 로고    scopus 로고
    • Sustained phenotypic correction of murine hemophilia A by in vivo gene therapy
    • Connelly S, Andrews JL, Gallo AM, et al. Sustained phenotypic correction of murine hemophilia A by in vivo gene therapy. Blood 1998;91:3273-3281
    • (1998) Blood , vol.91 , pp. 3273-3281
    • Connelly, S.1    Andrews, J.L.2    Gallo, A.M.3
  • 52
    • 0031974739 scopus 로고    scopus 로고
    • Reversal of hypercholesterolemia in apolipoprotein E2 and apolipoprotein E3-leiden transgenic mice by adenovirus-mediated gene transfer of the VLDL receptor
    • van Dijk KW, van Vlijmen BJ, van der Zee A, et al. Reversal of hypercholesterolemia in apolipoprotein E2 and apolipoprotein E3-Leiden transgenic mice by adenovirus-mediated gene transfer of the VLDL receptor. Arterioscler Thromb Biol 1998; 18:7-12
    • (1998) Arterioscler Thromb Biol , vol.18 , pp. 7-12
    • Van Dijk, K.W.1    Van Vlijmen, B.J.2    Van Der Zee, A.3
  • 53
    • 0032032633 scopus 로고    scopus 로고
    • Gene therapy with bilirubin-UDP-glucuronosyltransferase in the Gunn rat model of Crigler-Najjar syndrome type 1
    • Li O, Murphree SS, Willer SS, Bolli R, French BA. Gene therapy with bilirubin-UDP-glucuronosyltransferase in the Gunn rat model of Crigler-Najjar syndrome type 1. Hum Gene Ther 1998; 9:497-505
    • (1998) Hum Gene Ther , vol.9 , pp. 497-505
    • Li, O.1    Murphree, S.S.2    Willer, S.S.3    Bolli, R.4    French, B.A.5
  • 54
    • 0031019586 scopus 로고    scopus 로고
    • Adenovirus-mediated gene transfer and expression of human beta-glucuronidase gene in the liver, spleen, and central nervous system in mucopolysaccharidosis type VII mice
    • Ohashi T, Watabe K, Uehara K, Sly WS, Vogler C, Eto Y. Adenovirus-mediated gene transfer and expression of human beta-glucuronidase gene in the liver, spleen, and central nervous system in mucopolysaccharidosis type VII mice. Proc Natl Acad Sci U S A 1997;94:1287-1292
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 1287-1292
    • Ohashi, T.1    Watabe, K.2    Uehara, K.3    Sly, W.S.4    Vogler, C.5    Eto, Y.6
  • 55
    • 0030666462 scopus 로고    scopus 로고
    • Adenovirus-mediated gene transfer of human lipoprotein lipase ameliorates the hyperlipidemias associated with apolipoprotein E and LDL receptor deficiencies in mice
    • Zsigmond E, Kobayashi K, Tzung KW, Li L, Fuke Y, Chan L. Adenovirus-mediated gene transfer of human lipoprotein lipase ameliorates the hyperlipidemias associated with apolipoprotein E and LDL receptor deficiencies in mice. Hum Gene Ther 1997; 8:1921-1933
    • (1997) Hum Gene Ther , vol.8 , pp. 1921-1933
    • Zsigmond, E.1    Kobayashi, K.2    Tzung, K.W.3    Li, L.4    Fuke, Y.5    Chan, L.6
  • 56
    • 0029784403 scopus 로고    scopus 로고
    • Somatic gene therapy for phenylketonuria and other hepatic deficiencies
    • Eisensmith RC, Woo SLC. Somatic gene therapy for phenylketonuria and other hepatic deficiencies. J Inher Metab Dis 1996; 19:412-423
    • (1996) J Inher Metab Dis , vol.19 , pp. 412-423
    • Eisensmith, R.C.1    Woo, S.L.C.2
  • 57
    • 0029928640 scopus 로고    scopus 로고
    • Gene therapy for ornithine transcarbamylase deficiency
    • Kiwaki K, Matsuda I. Gene therapy for ornithine transcarbamylase deficiency. Acta Paediatr Jpn 1996;38:189-192
    • (1996) Acta Paediatr Jpn , vol.38 , pp. 189-192
    • Kiwaki, K.1    Matsuda, I.2
  • 58
    • 0031864774 scopus 로고    scopus 로고
    • Incidence and prevalence of neutralizing antibodies to the common adenoviruses in children with cystic fibrosis: Implication for gene therapy with adenovirus vectors
    • Piedra PA, Poveda GA, Ramsey B, McCoy K, Hiatt PW. Incidence and prevalence of neutralizing antibodies to the common adenoviruses in children with cystic fibrosis: Implication for gene therapy with adenovirus vectors. Pediatrics 1998;101: 1013-1019
    • (1998) Pediatrics , vol.101 , pp. 1013-1019
    • Piedra, P.A.1    Poveda, G.A.2    Ramsey, B.3    McCoy, K.4    Hiatt, P.W.5
  • 59
    • 9244220682 scopus 로고    scopus 로고
    • Immune responses to viral antigens versus transgene product in the elimination of recombinant adenovirus-infected hepatocytes in vivo
    • Yang Y, Jooss KU, Su Q, Ertl HC, Wilson JM. Immune responses to viral antigens versus transgene product in the elimination of recombinant adenovirus-infected hepatocytes in vivo. Gene Ther 1996;3:137-144
    • (1996) Gene Ther , vol.3 , pp. 137-144
    • Yang, Y.1    Jooss, K.U.2    Su, Q.3    Ertl, H.C.4    Wilson, J.M.5
  • 60
    • 0028484704 scopus 로고
    • MHC class I-restricted cytotoxic T lymphocytes to viral antigens destroy hepatocytes in mice infected with E1-deleted recombinant adenoviruses
    • Yang Y, Ertl HC, Wilson JM. MHC class I-restricted cytotoxic T lymphocytes to viral antigens destroy hepatocytes in mice infected with E1-deleted recombinant adenoviruses. Immunity 1994;1:433-442
    • (1994) Immunity , vol.1 , pp. 433-442
    • Yang, Y.1    Ertl, H.C.2    Wilson, J.M.3
  • 61
    • 0028168641 scopus 로고
    • Administration of an adenovirus containing the human CFTR cDNA to the respiratory tract of individuals with cystic fibrosis
    • Crystal RG, McElvaney NG, Rosenfeld MA, et al. Administration of an adenovirus containing the human CFTR cDNA to the respiratory tract of individuals with cystic fibrosis. Nat Genet 1994;8:42-51
    • (1994) Nat Genet , vol.8 , pp. 42-51
    • Crystal, R.G.1    McElvaney, N.G.2    Rosenfeld, M.A.3
  • 62
    • 0029849258 scopus 로고    scopus 로고
    • Portal branch occlusion safely facilitates in vivo retroviral vector transduction of rat liver
    • Bowling WM, Kennedy SC, Cai SR, et al. Portal branch occlusion safely facilitates in vivo retroviral vector transduction of rat liver. Hum Gene Ther 1996;7:2113-2121
    • (1996) Hum Gene Ther , vol.7 , pp. 2113-2121
    • Bowling, W.M.1    Kennedy, S.C.2    Cai, S.R.3
  • 63
    • 0029886198 scopus 로고    scopus 로고
    • Hepatocyte growth factor expressed by a retrovirus-producing cell line enhances retroviral transduction of primary hepatocytes: Implications for in vivo gene transfer
    • Pages JC, Loux N, Bellusci S, et al. Hepatocyte growth factor expressed by a retrovirus-producing cell line enhances retroviral transduction of primary hepatocytes: Implications for in vivo gene transfer. Biochem Biophys Res Commun 1996;222:726-731
    • (1996) Biochem Biophys Res Commun , vol.222 , pp. 726-731
    • Pages, J.C.1    Loux, N.2    Bellusci, S.3
  • 64
    • 0029875835 scopus 로고    scopus 로고
    • Hepatocytes corrected by gene therapy are selected in vivo in a murine model of hereditary tyrosinaemia type I
    • Overturf K, Al-Dhalimy M, Tanguay R, et al. Hepatocytes corrected by gene therapy are selected in vivo in a murine model of hereditary tyrosinaemia type I. Nat Genet 1996;12:266-273
    • (1996) Nat Genet , vol.12 , pp. 266-273
    • Overturf, K.1    Al-Dhalimy, M.2    Tanguay, R.3
  • 65
    • 0029010354 scopus 로고
    • Adenovirus-mediated urokinase gene transfer induces liver regeneration and allows for efficient retrovirus transduction of hepatocytes in vivo
    • Lieber A, Vrancken Peeters MJ, Meuse L, Fausto N, Perkins J, Kay MA. Adenovirus-mediated urokinase gene transfer induces liver regeneration and allows for efficient retrovirus transduction of hepatocytes in vivo. Proc Natl Acad Sci U S A 1995;92:6210-6214
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 6210-6214
    • Lieber, A.1    Vrancken Peeters, M.J.2    Meuse, L.3    Fausto, N.4    Perkins, J.5    Kay, M.A.6
  • 66
    • 0031008929 scopus 로고    scopus 로고
    • Persistent transgene expression in mouse liver following in vivo gene transfer with a delta E1/delta E4 adenovirus vector
    • Wang Q, Greenburg G, Bunch D, Farson D, Finer MH. Persistent transgene expression in mouse liver following in vivo gene transfer with a delta E1/delta E4 adenovirus vector. Gene Ther 1997;4:393-400
    • (1997) Gene Ther , vol.4 , pp. 393-400
    • Wang, Q.1    Greenburg, G.2    Bunch, D.3    Farson, D.4    Finer, M.H.5
  • 67
    • 0031060294 scopus 로고    scopus 로고
    • Enhancement of in vivo adenovirus-mediated gene transfer and expression by prior depletion of tissue macrophages in the target organ
    • Wolff G, Worgall S, van Rooijen N, Song WR, Harvey BG, Crystal RG. Enhancement of in vivo adenovirus-mediated gene transfer and expression by prior depletion of tissue macrophages in the target organ. J Virol 1997;71:624-629
    • (1997) J Virol , vol.71 , pp. 624-629
    • Wolff, G.1    Worgall, S.2    Van Rooijen, N.3    Song, W.R.4    Harvey, B.G.5    Crystal, R.G.6
  • 68
    • 0029959867 scopus 로고    scopus 로고
    • Biology of adenovirus vectors with E1 and E4 deletions for liver-directed gene therapy
    • Gao GP. Yang Y, Wilson JM. Biology of adenovirus vectors with E1 and E4 deletions for liver-directed gene therapy. J Virol 1996;70:8934-8943
    • (1996) J Virol , vol.70 , pp. 8934-8943
    • Gao, G.P.1    Yang, Y.2    Wilson, J.M.3
  • 69
    • 0029944988 scopus 로고    scopus 로고
    • Transient immune blockade prevents formation of neutralizing antibody to recombinant adenovirus and allows repeated gene transfer to mouse liver
    • Yang Y, Greenough K, Wilson JM. Transient immune blockade prevents formation of neutralizing antibody to recombinant adenovirus and allows repeated gene transfer to mouse liver. Gene Ther 1996;3:412-420
    • (1996) Gene Ther , vol.3 , pp. 412-420
    • Yang, Y.1    Greenough, K.2    Wilson, J.M.3
  • 70
    • 0023212742 scopus 로고
    • Receptor-mediated in vitro gene transformation by a soluble DNA carrier system
    • Wu G, Wu C. Receptor-mediated in vitro gene transformation by a soluble DNA carrier system. J Biol Chem 1987;262:4429-4432
    • (1987) J Biol Chem , vol.262 , pp. 4429-4432
    • Wu, G.1    Wu, C.2
  • 71
    • 0023811723 scopus 로고
    • Receptor-mediated gene delivery and expression in vivo
    • Wu GY, Wu CH. Receptor-mediated gene delivery and expression in vivo. J Biol Chem 1988;263:14621-14624
    • (1988) J Biol Chem , vol.263 , pp. 14621-14624
    • Wu, G.Y.1    Wu, C.H.2
  • 72
    • 0024343077 scopus 로고
    • Targeting genes: Delivery and persistent expression of a foreign gene driven by mammalian regulatory elements in vivo
    • Wu CH, Wilson JM, Wu GY. Targeting genes: Delivery and persistent expression of a foreign gene driven by mammalian regulatory elements in vivo. J Biol Chem 1989;264:16985-16987
    • (1989) J Biol Chem , vol.264 , pp. 16985-16987
    • Wu, C.H.1    Wilson, J.M.2    Wu, G.Y.3
  • 75
    • 0028130678 scopus 로고
    • The asialoglycoprotein receptor mediates hepatic binding and uptake of natural hepatitis B virus particles derived from viraemic carriers
    • Treichel U, Meyer zum Buschenfelde KH, Stockert RJ, Poralla T, Gerken G. The asialoglycoprotein receptor mediates hepatic binding and uptake of natural hepatitis B virus particles derived from viraemic carriers. J Gen Virol 1994;75:3021-3029
    • (1994) J Gen Virol , vol.75 , pp. 3021-3029
    • Treichel, U.1    Meyer Zum Buschenfelde, K.H.2    Stockert, R.J.3    Poralla, T.4    Gerken, G.5
  • 77
    • 0031281282 scopus 로고    scopus 로고
    • In vitro gene delivery to hepatocytes with galactosylated polyethylenimine
    • Zanta MA, Boussif O, Adib A, Behr JP. In vitro gene delivery to hepatocytes with galactosylated polyethylenimine. Bioconjug Chem 1997;8:839-844
    • (1997) Bioconjug Chem , vol.8 , pp. 839-844
    • Zanta, M.A.1    Boussif, O.2    Adib, A.3    Behr, J.P.4
  • 78
    • 0029160083 scopus 로고
    • A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: Polyethylenimine
    • Boussif O, Lezoualc'h F, Zanta MA, et al. A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: Polyethylenimine. Proc Natl Acad Sci U S A 1995;92: 7297-7301
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 7297-7301
    • Boussif, O.1    Lezoualc'h, F.2    Zanta, M.A.3
  • 79
    • 0030896557 scopus 로고    scopus 로고
    • Biochemical and functional characterization of DNA complexes capable of targeting genes to hepatocytes via the asialoglycoprotein receptor
    • Perales JC, Grossmann GA, Molas M, et al. Biochemical and functional characterization of DNA complexes capable of targeting genes to hepatocytes via the asialoglycoprotein receptor. J Biol Chem 1997;272:7398-7407
    • (1997) J Biol Chem , vol.272 , pp. 7398-7407
    • Perales, J.C.1    Grossmann, G.A.2    Molas, M.3
  • 80
    • 0028223310 scopus 로고
    • Gene transfer in vivo: Sustained expression and regulation of genes introduced into the liver by receptor-targeted uptake
    • Perales JC, Ferkol T, Beegen H, Ratnoff OD, Hanson RW. Gene transfer in vivo: Sustained expression and regulation of genes introduced into the liver by receptor-targeted uptake. Proc Natl Acad Sci U S A 1994;91:4086-4090
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 4086-4090
    • Perales, J.C.1    Ferkol, T.2    Beegen, H.3    Ratnoff, O.D.4    Hanson, R.W.5
  • 81
    • 0025158071 scopus 로고
    • Uptake of lactosylated low-density lipoprotein by galactose-specific receptors in rat liver
    • Bijsterbosch MK, van Berkel TJC. Uptake of lactosylated low-density lipoprotein by galactose-specific receptors in rat liver. Biochem J 1990;270:233-239
    • (1990) Biochem J , vol.270 , pp. 233-239
    • Bijsterbosch, M.K.1    Van Berkel, T.J.C.2
  • 82
    • 0029558004 scopus 로고
    • Cationic liposome-mediated gene transfer
    • Gao X, Huang L. Cationic liposome-mediated gene transfer. Gene Ther 1995;2:710-722
    • (1995) Gene Ther , vol.2 , pp. 710-722
    • Gao, X.1    Huang, L.2
  • 83
    • 0028913411 scopus 로고
    • Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis
    • Caplen NJ, Alton EW, Middleton PG, et al. Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis. Nat Med 1995;1:39-46
    • (1995) Nat Med , vol.1 , pp. 39-46
    • Caplen, N.J.1    Alton, E.W.2    Middleton, P.G.3
  • 84
    • 0027517321 scopus 로고
    • Direct gene transfer with DNA-liposome complexes in melanoma: Expression, biologic activity, and lack of toxicity in humans
    • Nabel GJ, Nabel EG, Yang ZY, et al. Direct gene transfer with DNA-liposome complexes in melanoma: Expression, biologic activity, and lack of toxicity in humans. Proc Natl Acad Sci U S A 1993;90:11307-11311
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 11307-11311
    • Nabel, G.J.1    Nabel, E.G.2    Yang, Z.Y.3
  • 85
    • 0029967080 scopus 로고    scopus 로고
    • Fate of cationic liposomes and their complex with oligonucleotide in vivo
    • Litzinger DC, Brown JM, Wala I, et al. Fate of cationic liposomes and their complex with oligonucleotide in vivo. Biochim Biophys Acta 1996;1281:139-149
    • (1996) Biochim Biophys Acta , vol.1281 , pp. 139-149
    • Litzinger, D.C.1    Brown, J.M.2    Wala, I.3
  • 86
    • 4244142621 scopus 로고    scopus 로고
    • Organ-specific endothelial cell uptake of cationic liposome-DNA complexes in mice
    • McLean JW, Fox EA, Baluk P, et al. Organ-specific endothelial cell uptake of cationic liposome-DNA complexes in mice. Am J Physiol 1997;273:H387-404
    • (1997) Am J Physiol , vol.273
    • McLean, J.W.1    Fox, E.A.2    Baluk, P.3
  • 87
    • 0030599360 scopus 로고    scopus 로고
    • Co-existence of serum-dependent and serum-independent mechanisms for liposome clearance and involvement of non-Kupffer cells in liposome uptake by mouse liver
    • Hu Q, Liu D. Co-existence of serum-dependent and serum-independent mechanisms for liposome clearance and involvement of non-Kupffer cells in liposome uptake by mouse liver. Biochim Biophys Acta 1996;1284:153-161
    • (1996) Biochim Biophys Acta , vol.1284 , pp. 153-161
    • Hu, Q.1    Liu, D.2
  • 88
    • 0030010148 scopus 로고    scopus 로고
    • Human alpha 1-antitrypsin gene transfer to in vivo mouse hepatocytes
    • Alino SF, Bobadilla M, Crespo J, Lejarreta M. Human alpha 1-antitrypsin gene transfer to in vivo mouse hepatocytes. Hum Gene Ther 1996;7:531-536
    • (1996) Hum Gene Ther , vol.7 , pp. 531-536
    • Alino, S.F.1    Bobadilla, M.2    Crespo, J.3    Lejarreta, M.4
  • 89
    • 0030750566 scopus 로고    scopus 로고
    • Uptake of charged liposomes by the rat liver
    • Yu HY, Lin CY. Uptake of charged liposomes by the rat liver. J Formos Med Assoc 1997;96:409-413
    • (1997) J Formos Med Assoc , vol.96 , pp. 409-413
    • Yu, H.Y.1    Lin, C.Y.2
  • 90
    • 0030858780 scopus 로고    scopus 로고
    • Long-term expression of the human alpha 1-anthrypsin gene in mice employing anionic and cationic liposome vector
    • Alino SF. Long-term expression of the human alpha 1-anthrypsin gene in mice employing anionic and cationic liposome vector. Biochem Pharmacol 1997;54:9-13
    • (1997) Biochem Pharmacol , vol.54 , pp. 9-13
    • Alino, S.F.1
  • 91
    • 0030813879 scopus 로고    scopus 로고
    • Factors controlling the efficiency of cationic lipid-mediated transfection in vivo via intravenous administration
    • Liu F, Qi H, Huang L, Liu D. Factors controlling the efficiency of cationic lipid-mediated transfection in vivo via intravenous administration. Gene Ther 1997;4:517-523
    • (1997) Gene Ther , vol.4 , pp. 517-523
    • Liu, F.1    Qi, H.2    Huang, L.3    Liu, D.4
  • 92
    • 0030942803 scopus 로고    scopus 로고
    • Characterization of liposome-mediated gene delivery: Expression, stability and pharmacokinetics of plasmid DNA
    • Theirry AR, Rabinovich P, Peng B, Mahan LC, Bryant JL, Gallo RC. Characterization of liposome-mediated gene delivery: Expression, stability and pharmacokinetics of plasmid DNA. Gene Ther 1997;4:226-237
    • (1997) Gene Ther , vol.4 , pp. 226-237
    • Theirry, A.R.1    Rabinovich, P.2    Peng, B.3    Mahan, L.C.4    Bryant, J.L.5    Gallo, R.C.6
  • 93
    • 0031436819 scopus 로고    scopus 로고
    • Complementation of the genetic defect in Gunn rat hepatocytes in vitro by highly efficient gene transfer with cationic liposomes
    • Wilke M, Bijma A, Timmers-Reker AJ, Scholte BJ, Sinaasappel M. Complementation of the genetic defect in Gunn rat hepatocytes in vitro by highly efficient gene transfer with cationic liposomes. Gene Ther 1997;4:1305-1312
    • (1997) Gene Ther , vol.4 , pp. 1305-1312
    • Wilke, M.1    Bijma, A.2    Timmers-Reker, A.J.3    Scholte, B.J.4    Sinaasappel, M.5
  • 94
    • 0030034616 scopus 로고    scopus 로고
    • Serum independent liposome uptake by mouse liver
    • Liu F, Liu D. Serum independent liposome uptake by mouse liver. Biochim Biophys Acta 1996;1278:5-11
    • (1996) Biochim Biophys Acta , vol.1278 , pp. 5-11
    • Liu, F.1    Liu, D.2
  • 95
    • 0029979842 scopus 로고    scopus 로고
    • Improvement of pharmacokinetics and antitumor activity against human hepatoma cell line by using adriamycin-entrapped stealth liposomes
    • Shimizu H, Kumai K, Uyama I, et al. Improvement of pharmacokinetics and antitumor activity against human hepatoma cell line by using adriamycin-entrapped stealth liposomes. J Surg Oncol 1996;62:186-193
    • (1996) J Surg Oncol , vol.62 , pp. 186-193
    • Shimizu, H.1    Kumai, K.2    Uyama, I.3
  • 97
    • 0028245540 scopus 로고
    • Receptor-mediated gene transfer into hepatic cells using asialoglycoprotein-labeled liposomes
    • Koike K, Hara T, Aramaki Y, Takada S, Tsuchiya S. Receptor-mediated gene transfer into hepatic cells using asialoglycoprotein-labeled liposomes. Ann N Y Acad Sci 1994;716:331-333
    • (1994) Ann N Y Acad Sci , vol.716 , pp. 331-333
    • Koike, K.1    Hara, T.2    Aramaki, Y.3    Takada, S.4    Tsuchiya, S.5
  • 98
    • 0029616558 scopus 로고
    • Receptor-mediated transfer of pSV2CAT DNA to mouse liver cells using asialofetuin-labeled liposomes
    • Hara T, Aramaki Y, Takada S, Koike K, Tsuchiya S. Receptor-mediated transfer of pSV2CAT DNA to mouse liver cells using asialofetuin-labeled liposomes. Gene Ther 1995;2:784-788
    • (1995) Gene Ther , vol.2 , pp. 784-788
    • Hara, T.1    Aramaki, Y.2    Takada, S.3    Koike, K.4    Tsuchiya, S.5
  • 99
    • 0031891520 scopus 로고    scopus 로고
    • Increased liver uptake of liposomes and improved targeting efficacy by labeling with asialofetuin in rodents
    • Wu J, Liu P, Zhu JL, Maddukuri S, Zern MA. Increased liver uptake of liposomes and improved targeting efficacy by labeling with asialofetuin in rodents. Hepatology 1998;27:772-778
    • (1998) Hepatology , vol.27 , pp. 772-778
    • Wu, J.1    Liu, P.2    Zhu, J.L.3    Maddukuri, S.4    Zern, M.A.5
  • 100
    • 0030888956 scopus 로고    scopus 로고
    • Hepatic accumulation of glutamic acid branched neogalactosyl-lipid modified liposomes
    • Murahashi N, Ishihara H, Sasaki A, Sakagami M, Hamana H. Hepatic accumulation of glutamic acid branched neogalactosyl-lipid modified liposomes. Biol Pharm Bull 1997;20:259-266
    • (1997) Biol Pharm Bull , vol.20 , pp. 259-266
    • Murahashi, N.1    Ishihara, H.2    Sasaki, A.3    Sakagami, M.4    Hamana, H.5
  • 101
    • 0030979210 scopus 로고    scopus 로고
    • Biodistribution of liposomes containing synthetic galactose-terminated diacylglyceryl-poly(ethyleneglycol)s
    • Shimada K, Kamps JA, Regts J, et al. Biodistribution of liposomes containing synthetic galactose-terminated diacylglyceryl-poly(ethyleneglycol)s. Biochim Biophys Acta 1997;1326:329-341
    • (1997) Biochim Biophys Acta , vol.1326 , pp. 329-341
    • Shimada, K.1    Kamps, J.A.2    Regts, J.3
  • 102
    • 0030761292 scopus 로고    scopus 로고
    • Formulation of liposomes with a soybean-derived stearylglucoside mixture and cholesterol for liver targeting
    • Shimizu K, Maitani Y, Takayama K, Nagai T. Formulation of liposomes with a soybean-derived stearylglucoside mixture and cholesterol for liver targeting. Biol Pharm Bull 1997;20:881-886
    • (1997) Biol Pharm Bull , vol.20 , pp. 881-886
    • Shimizu, K.1    Maitani, Y.2    Takayama, K.3    Nagai, T.4
  • 103
    • 0029877957 scopus 로고    scopus 로고
    • Coating liposomes with collagen (Mr 50,000) increases uptake into liver
    • Fonseca MJ, Alsina MA, Reig F. Coating liposomes with collagen (Mr 50,000) increases uptake into liver. Biochim Biophys Acta 1996;1279:259-265
    • (1996) Biochim Biophys Acta , vol.1279 , pp. 259-265
    • Fonseca, M.J.1    Alsina, M.A.2    Reig, F.3
  • 104
    • 0030822608 scopus 로고    scopus 로고
    • Massive targeting of liposomes, surface-modified with anionized albumins, to hepatic endothelial cells
    • Kamps JA, Morselt HW, Swart PJ, Meijer DK, Scherphof GL. Massive targeting of liposomes, surface-modified with anionized albumins, to hepatic endothelial cells. Proc Natl Acad Sci U S A 1997:94:11681-11685
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 11681-11685
    • Kamps, J.A.1    Morselt, H.W.2    Swart, P.J.3    Meijer, D.K.4    Scherphof, G.L.5
  • 105
    • 0030987679 scopus 로고    scopus 로고
    • Receptor mediated delivery of daunomycin using immunoliposomes: Pharmacokinetics and tissue distribution in the rat
    • Huwyler J, Yang J, Pardridge WM. Receptor mediated delivery of daunomycin using immunoliposomes: Pharmacokinetics and tissue distribution in the rat. J Pharmacol Exp Ther 1997;282: 1541-1546
    • (1997) J Pharmacol Exp Ther , vol.282 , pp. 1541-1546
    • Huwyler, J.1    Yang, J.2    Pardridge, W.M.3
  • 106
    • 0030851111 scopus 로고    scopus 로고
    • Human recombinant apolipoprotein E-enriched liposomes can mimic low-density lipoproteins as carriers for the site-specific delivery of antitumor agents
    • Rensen PCN, Schiffelers RM, Versluis AJ, Bijsterbosch MK, Van Kuijk-Meuwissen ME, Van Berkel TJ. Human recombinant apolipoprotein E-enriched liposomes can mimic low-density lipoproteins as carriers for the site-specific delivery of antitumor agents. Mol Pharmacol 1997;52:445-455
    • (1997) Mol Pharmacol , vol.52 , pp. 445-455
    • Rensen, P.C.N.1    Schiffelers, R.M.2    Versluis, A.J.3    Bijsterbosch, M.K.4    Van Kuijk-Meuwissen, M.E.5    Van Berkel, T.J.6
  • 107
    • 0031005194 scopus 로고    scopus 로고
    • In vitro and in vivo gene delivery mediated by a synthetic polycationic amino polymer
    • Goldman CK, Soroceanu L, Smith N, et al. In vitro and in vivo gene delivery mediated by a synthetic polycationic amino polymer. Nat Biotechnol 1997;15:462-466
    • (1997) Nat Biotechnol , vol.15 , pp. 462-466
    • Goldman, C.K.1    Soroceanu, L.2    Smith, N.3


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