Evaluation of hepatitis C virus glycoprotein E2 for vaccine design: An endoplasmic reticulum-retained recombinant protein is superior to secreted recombinant protein and DNA-based vaccine candidates

Journal of Virology

Volumn 74, Issue 15, 2000, Pages 6885-6892

  Heile, Jens M ^a   Fong, Yiu Lian ^b   Rosa, Domenico ^a   Berger, Kim ^b   Saletti, Giulietta ^a   Campagnoli, Susanna ^a   Bensi, Giuliano ^a   Capo, Sabrina ^a   Coates, Steve ^b   Crawford, Kevin ^b   Dong, Christine ^b   Wininger, Mark ^b   Baker, Gary ^b   Cousens, Larry ^b   Chien, David ^b   Ng, Philip ^b   Archangel, Phillip ^b   Grandi, Guido ^a   Houghton, Michael ^b   Abrignani, Sergio ^a  

^a CHIRON VACCINES   (Italy)

^b NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; DNA VACCINE; ENVELOPE PROTEIN; HEPATITIS VACCINE; RECOMBINANT PROTEIN; RIBAVIRIN;

ARTICLE; CHO CELL; DRUG DESIGN; ENDOPLASMIC RETICULUM; HEPATITIS C VIRUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; VACCINATION; VIRUS ENVELOPE;

ANIMALS; ANTIGENS, CD; DRUG DESIGN; ENDOPLASMIC RETICULUM; EVALUATION STUDIES; FEMALE; GLYCOSYLATION; GUINEA PIGS; HEPACIVIRUS; HEPATITIS C; HEPATITIS C ANTIBODIES; HUMANS; IMMUNIZATION; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; RECOMBINANT PROTEINS; VACCINES, DNA; VIRAL ENVELOPE PROTEINS; VIRAL HEPATITIS VACCINES;

EID: 17544368390     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.74.15.6885-6892.2000     Document Type: Article

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