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Volumn 9, Issue 1, 2003, Pages 135-139

Ligand-directed targeting of genes to the site of disease

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; DIPEPTIDYL CARBOXYPEPTIDASE; LIGAND; MACROGOL; POLY[N (2 HYDROXYPROPYL)METHACRYLAMIDE]; POLYETHYLENEIMINE; POLYMER; RETROVIRUS VECTOR; TUMOR NECROSIS FACTOR ALPHA;

EID: 0037231625     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm0103-135     Document Type: Review
Times cited : (107)

References (69)
  • 2
    • 0033677510 scopus 로고    scopus 로고
    • A blood-tumor barrier limits gene transfer to experimental liver cancer: The effect of vasoactive compounds
    • Bilbao, R. et al. A blood-tumor barrier limits gene transfer to experimental liver cancer: the effect of vasoactive compounds. Gene Ther. 7, 1824-1832 (2000).
    • (2000) Gene Ther. , vol.7 , pp. 1824-1832
    • Bilbao, R.1
  • 3
    • 0036172153 scopus 로고    scopus 로고
    • Targeting of adenovirus vectors to tumor cells does not enable efficient transduction of breast cancer metastases
    • Shayakhmetov, D.M., Li, Z.Y., Ni, S. & Lieber, A. Targeting of adenovirus vectors to tumor cells does not enable efficient transduction of breast cancer metastases. Cancer Res. 62, 1063-1068 (2002).
    • (2002) Cancer Res. , vol.62 , pp. 1063-1068
    • Shayakhmetov, D.M.1    Li, Z.Y.2    Ni, S.3    Lieber, A.4
  • 4
    • 0030915715 scopus 로고    scopus 로고
    • HCAR MCAR: The human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackieviruses
    • Tomko, R.P., Xu, R. & Philipson, L. HCAR and MCAR: the human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackieviruses. Proc. Natl. Acad. Sci. USA 94, 3352-3356 (1997).
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 3352-3356
    • Tomko, R.P.1    Xu, R.2    Philipson, L.3
  • 5
    • 0031052263 scopus 로고    scopus 로고
    • Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5
    • Bergelson, J.M. et al. Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5. Science 275, 1320-1323 (1997).
    • (1997) Science , vol.275 , pp. 1320-1323
    • Bergelson, J.M.1
  • 6
    • 0027166647 scopus 로고
    • Integrins αvβ3 and αcβ5 promote adenovirus internalization but not virus attachment
    • Wickham, T.J., Mathias, P., Cheresh, D.A. & Nemerow, G.R. Integrins αvβ3 and αcβ5 promote adenovirus internalization but not virus attachment. Cell 73, 309-319 (1993).
    • (1993) Cell , vol.73 , pp. 309-319
    • Wickham, T.J.1    Mathias, P.2    Cheresh, D.A.3    Nemerow, G.R.4
  • 7
    • 0035158631 scopus 로고    scopus 로고
    • Reducing the native tropism of adenovirus vectors requires removal of both CAR and integrin interactions
    • Einfeld, D.A. et al. Reducing the native tropism of adenovirus vectors requires removal of both CAR and integrin interactions. J. Virol. 75, 11284-11291 (2001).
    • (2001) J. Virol. , vol.75 , pp. 11284-11291
    • Einfeld, D.A.1
  • 8
    • 0036118869 scopus 로고    scopus 로고
    • Adenovirus binding to the coxsackievirus and adenovirus receptor or integrins is not required to elicit brain inflammation but is necessary to transduce specific neural cell types
    • Thomas, C.E., Edwards, P., Wickham, T.J., Castro, M.G. & Lowenstein, P.R. Adenovirus binding to the coxsackievirus and adenovirus receptor or integrins is not required to elicit brain inflammation but is necessary to transduce specific neural cell types. J. Virol. 76, 3452-3460 (2002).
    • (2002) J. Virol. , vol.76 , pp. 3452-3460
    • Thomas, C.E.1    Edwards, P.2    Wickham, T.J.3    Castro, M.G.4    Lowenstein, P.R.5
  • 9
    • 0028790770 scopus 로고
    • Addition of a short peptide ligand to the adenovirus fiber protein
    • Michael, S.I., Hong, J.S., Curiel, D.T. & Engler, J.A. Addition of a short peptide ligand to the adenovirus fiber protein. Gene Ther. 2, 660-668 (1995).
    • (1995) Gene Ther. , vol.2 , pp. 660-668
    • Michael, S.I.1    Hong, J.S.2    Curiel, D.T.3    Engler, J.A.4
  • 10
    • 0030768124 scopus 로고    scopus 로고
    • Increased in vitro and in vivo gene transfer by adenovirus vectors containing chimeric fiber proteins
    • Wickham, T.J. et al. Increased in vitro and in vivo gene transfer by adenovirus vectors containing chimeric fiber proteins. J. Virol. 71, 8221-8229 (1997).
    • (1997) J. Virol. , vol.71 , pp. 8221-8229
    • Wickham, T.J.1
  • 11
    • 0032851439 scopus 로고    scopus 로고
    • Construction of a pseudoreceptor that mediates transduction by adenoviruses expressing a ligand in fiber or penton base
    • Einfeld, D.A., Brough, D.E., Roelvink, P.W., Kovesdi, I. & Wickham, T.J. Construction of a pseudoreceptor that mediates transduction by adenoviruses expressing a ligand in fiber or penton base. J. Virol. 73, 9130-9136 (1999).
    • (1999) J. Virol. , vol.73 , pp. 9130-9136
    • Einfeld, D.A.1    Brough, D.E.2    Roelvink, P.W.3    Kovesdi, I.4    Wickham, T.J.5
  • 12
    • 0033061221 scopus 로고    scopus 로고
    • RGD inclusion in the hexon monomer provides adenovirus type 5-based vectors with a fiber knob-independent pathway for infection
    • Vigne, E. et al. RGD inclusion in the hexon monomer provides adenovirus type 5-based vectors with a fiber knob-independent pathway for infection. J. Virol. 73, 5156-5161 (1999).
    • (1999) J. Virol. , vol.73 , pp. 5156-5161
    • Vigne, E.1
  • 13
    • 0032170198 scopus 로고    scopus 로고
    • Development of novel cell surface CD34-targeted recombinant adenoassociated virus vectors for gene therapy
    • Yang, Q. et al. Development of novel cell surface CD34-targeted recombinant adenoassociated virus vectors for gene therapy. Hum. Gene Ther. 9, 1929-1937 (1998).
    • (1998) Hum. Gene Ther. , vol.9 , pp. 1929-1937
    • Yang, Q.1
  • 14
    • 0033954001 scopus 로고    scopus 로고
    • Targeting adenovirus
    • Wickham, T.J. Targeting adenovirus. Gene Ther. 7, 110-114 (2000).
    • (2000) Gene Ther. , vol.7 , pp. 110-114
    • Wickham, T.J.1
  • 15
    • 0033007934 scopus 로고    scopus 로고
    • Targeted adeno-associated virus vector transduction of nonpermissive cells mediated by a bispecific F(ab′τ)2 antibody
    • Bartlett, J.S., Kleinschmidt, J., Boucher, R.C. & Samulski, R.J. Targeted adeno-associated virus vector transduction of nonpermissive cells mediated by a bispecific F(ab′τ)2 antibody. Nature Biotechnol. 17, 181-186 (1999).
    • (1999) Nature Biotechnol. , vol.17 , pp. 181-186
    • Bartlett, J.S.1    Kleinschmidt, J.2    Boucher, R.C.3    Samulski, R.J.4
  • 16
    • 0033578320 scopus 로고    scopus 로고
    • Retroviral vectors preloaded with a viral receptor-ligand bridge protein are targeted to specific cell types
    • Boerger, A.L., Snitkovsky, S. & Young, J.A. Retroviral vectors preloaded with a viral receptor-ligand bridge protein are targeted to specific cell types. Proc. Natl. Acad. Sci. USA 96, 9867-9872 (1999).
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 9867-9872
    • Boerger, A.L.1    Snitkovsky, S.2    Young, J.A.3
  • 17
    • 0033813743 scopus 로고    scopus 로고
    • A TVA-single-chain antibody fusion protein mediates specific targeting of a subgroup A avian leukosis virus vector to cells expressing a tumor-specific form of epidermal growth factor receptor
    • Snitkovsky, S., Niederman, T.M., Carter, B.S., Mulligan, R.C. & Young, J.A. A TVA-single-chain antibody fusion protein mediates specific targeting of a subgroup A avian leukosis virus vector to cells expressing a tumor-specific form of epidermal growth factor receptor. J. Virol. 74, 9540-9545 (2000).
    • (2000) J. Virol. , vol.74 , pp. 9540-9545
    • Snitkovsky, S.1    Niederman, T.M.2    Carter, B.S.3    Mulligan, R.C.4    Young, J.A.5
  • 18
    • 0035152288 scopus 로고    scopus 로고
    • Targeting avian leukosis virus subgroup A vectors by using a TVA-VEGF bridge protein
    • Snitkovsky, S., Niederman, T.M, Mulligan, R.C. & Young, J.A. Targeting avian leukosis virus subgroup A vectors by using a TVA-VEGF bridge protein. J. Virol. 75, 1571-1575 (2001).
    • (2001) J. Virol. , vol.75 , pp. 1571-1575
    • Snitkovsky, S.1    Niederman, T.M.2    Mulligan, R.C.3    Young, J.A.4
  • 19
    • 0036058346 scopus 로고    scopus 로고
    • Targeting retroviral vector infection to cells that express heregulin receptors using a TVA-heregulin bridge protein
    • Snitkovsky, S. & Young, J.A. Targeting retroviral vector infection to cells that express heregulin receptors using a TVA-heregulin bridge protein. Virology 292, 150-155 (2002).
    • (2002) Virology , vol.292 , pp. 150-155
    • Snitkovsky, S.1    Young, J.A.2
  • 20
    • 0030835821 scopus 로고    scopus 로고
    • Cell-specific targeting of Sindbis virus vectors displaying IgG-binding domains of protein A
    • Ohno, K., Sawai, K., lijima, Y., Levin, B. & Meruelo, D. Cell-specific targeting of Sindbis virus vectors displaying IgG-binding domains of protein A. Nature Biotechnol. 15, 763-767 (1997).
    • (1997) Nature Biotechnol. , vol.15 , pp. 763-767
    • Ohno, K.1    Sawai, K.2    Iijima, Y.3    Levin, B.4    Meruelo, D.5
  • 21
    • 0033925797 scopus 로고    scopus 로고
    • Ectodomain of coxsackievirus and adenovirus receptor genetically fused to epidermal growth factor mediates adenovirus targeting to epidermal growth factor receptor-positive cells
    • Dmitriev, I., Kashentseva, E., Rogers, B.E., Krasnykh, V. & Curiel, D.T. Ectodomain of coxsackievirus and adenovirus receptor genetically fused to epidermal growth factor mediates adenovirus targeting to epidermal growth factor receptor-positive cells. J. Virol. 74, 6875-6884 (2000).
    • (2000) J. Virol. , vol.74 , pp. 6875-6884
    • Dmitriev, I.1    Kashentseva, E.2    Rogers, B.E.3    Krasnykh, V.4    Curiel, D.T.5
  • 22
    • 0029907239 scopus 로고    scopus 로고
    • Targeted gene delivery by tropism-modified adenoviral vectors
    • Douglas, J.T. et al. Targeted gene delivery by tropism-modified adenoviral vectors. Nature Biotechnol. 14, 1574-1578 (1996).
    • (1996) Nature Biotechnol. , vol.14 , pp. 1574-1578
    • Douglas, J.T.1
  • 23
    • 0036146390 scopus 로고    scopus 로고
    • Targeting adenoviral vectors by using the extracellular domain of the coxsackie-adenovirus receptor: Improved potency via trimerization
    • Kim, J. et al. Targeting adenoviral vectors by using the extracellular domain of the coxsackie-adenovirus receptor: improved potency via trimerization. J. Virol. 76, 1892-1903 (2002).
    • (2002) J. Virol. , vol.76 , pp. 1892-1903
    • Kim, J.1
  • 24
    • 0037189380 scopus 로고    scopus 로고
    • Tumor regression by targeted gene delivery to the neovasculature
    • Hood, J.D. et al. Tumor regression by targeted gene delivery to the neovasculature. Science 296, 2404-2407 (2002).
    • (2002) Science , vol.296 , pp. 2404-2407
    • Hood, J.D.1
  • 25
    • 0034963191 scopus 로고    scopus 로고
    • Targeting of adenovirus to endothelial cells by a bispecific single-chain diabody directed against the adenovirus fiber knob domain and human endoglin (CD105)
    • Nettelbeck, D.M. et al. Targeting of adenovirus to endothelial cells by a bispecific single-chain diabody directed against the adenovirus fiber knob domain and human endoglin (CD105). Mol. Ther. 3, 882-891 (2001).
    • (2001) Mol. Ther. , vol.3 , pp. 882-891
    • Nettelbeck, D.M.1
  • 26
    • 0033019077 scopus 로고    scopus 로고
    • Targeting an adenoviral gene vector to cytokine-activated vascular endothelium via E-selectin
    • Harari, O.A. et al. Targeting an adenoviral gene vector to cytokine-activated vascular endothelium via E-selectin. Gene Ther. 6, 801-807 (1999).
    • (1999) Gene Ther. , vol.6 , pp. 801-807
    • Harari, O.A.1
  • 27
    • 0030830511 scopus 로고    scopus 로고
    • Targeting endothelium for gene therapy via receptors up-regulated during angiogenesis and inflammation
    • Wickham, T.J., Haskard, D., Segal, D. & Kovesdi, I. Targeting endothelium for gene therapy via receptors up-regulated during angiogenesis and inflammation. Cancer Immunol. Immunother. 45, 149-151 (1997).
    • (1997) Cancer Immunol. Immunother. , vol.45 , pp. 149-151
    • Wickham, T.J.1    Haskard, D.2    Segal, D.3    Kovesdi, I.4
  • 28
    • 0034917310 scopus 로고    scopus 로고
    • Selective gene delivery toward gastric and esophageal adenocarcinoma cells via EpCAM-targeted adenoviral vectors
    • Heideman, D.A. et al. Selective gene delivery toward gastric and esophageal adenocarcinoma cells via EpCAM-targeted adenoviral vectors. Cancer Gene Ther. 8, 342-351 (2001).
    • (2001) Cancer Gene Ther. , vol.8 , pp. 342-351
    • Heideman, D.A.1
  • 29
    • 0034861664 scopus 로고    scopus 로고
    • Combined transductional and transcriptional targeting improves the specificity of transgene expression in vivo
    • Reynolds, P.N. et al. Combined transductional and transcriptional targeting improves the specificity of transgene expression in vivo. Nature Biotechnol. 19, 838-842 (2001).
    • (2001) Nature Biotechnol. , vol.19 , pp. 838-842
    • Reynolds, P.N.1
  • 30
    • 0012562018 scopus 로고    scopus 로고
    • Genetic targeting of retroviral vectors
    • eds. Curiel, D.T. & Douglas, J.T., Wiley-Liss, Hoboken, NJ
    • Dingli, D. & Russell, S.J. Genetic targeting of retroviral vectors. in Vector Targeting for Therapeutic Gene Delivery (eds. Curiel, D.T. & Douglas, J.T.) 267-291 (Wiley-Liss, Hoboken, NJ, 2002).
    • (2002) Vector Targeting for Therapeutic Gene Delivery , pp. 267-291
    • Dingli, D.1    Russell, S.J.2
  • 31
    • 0027172622 scopus 로고
    • Retroviral vectors displaying functional antibody fragments
    • Russell, S.J., Hawkins, R.E. & Winter, G. Retroviral vectors displaying functional antibody fragments. Nucleic Acids Res. 21, 1081-1085 (1993).
    • (1993) Nucleic Acids Res. , vol.21 , pp. 1081-1085
    • Russell, S.J.1    Hawkins, R.E.2    Winter, G.3
  • 32
    • 0028567517 scopus 로고
    • Tissue-specific targeting of retroviral vectors through ligand-receptor interactions
    • Kasahara, N., Dozy, A.M. & Kan, Y.W. Tissue-specific targeting of retroviral vectors through ligand-receptor interactions. Science 266, 1373-1376 (1994).
    • (1994) Science , vol.266 , pp. 1373-1376
    • Kasahara, N.1    Dozy, A.M.2    Kan, Y.W.3
  • 33
    • 0029094549 scopus 로고
    • Retroviral retargeting by envelopes expressing an N-terminal binding domain
    • Cosset, F.L. et al. Retroviral retargeting by envelopes expressing an N-terminal binding domain. J. Virol. 69, 6314-6322 (1995).
    • (1995) J. Virol. , vol.69 , pp. 6314-6322
    • Cosset, F.L.1
  • 34
    • 0028352506 scopus 로고
    • Modifications in the binding domain of avian retrovirus envelope protein to redirect the host range of retroviral vectors
    • Valsesia-Wittmann, S. et al. Modifications in the binding domain of avian retrovirus envelope protein to redirect the host range of retroviral vectors. J. Virol. 68, 4609-4619 (1994).
    • (1994) J. Virol. , vol.68 , pp. 4609-4619
    • Valsesia-Wittmann, S.1
  • 35
    • 0033542387 scopus 로고    scopus 로고
    • Retroviral display of functional binding domains fused to the amino terminus of influenza hemagglutinin
    • Hatziioannou, T., Delahaye, E., Martin, F., Russell, S.J. & Cosset, F.L. Retroviral display of functional binding domains fused to the amino terminus of influenza hemagglutinin. Hum. Gene Ther. 10, 1533-1544 (1999).
    • (1999) Hum. Gene Ther. , vol.10 , pp. 1533-1544
    • Hatziioannou, T.1    Delahaye, E.2    Martin, F.3    Russell, S.J.4    Cosset, F.L.5
  • 36
    • 0031582620 scopus 로고    scopus 로고
    • Masking of retroviral envelope functions by oligomerizing polypeptide adaptors
    • Morling, F.J., Peng, K.W., Cosset, F.L. & Russell, S.J. Masking of retroviral envelope functions by oligomerizing polypeptide adaptors. Virology 234, 51-61 (1997).
    • (1997) Virology , vol.234 , pp. 51-61
    • Morling, F.J.1    Peng, K.W.2    Cosset, F.L.3    Russell, S.J.4
  • 37
    • 0032846999 scopus 로고    scopus 로고
    • Selective transduction of proteaserich tumors by matrix-metalloproteinase-targeted retroviral vectors
    • Peng, K.W., Vile, R., Cosset, F.L. & Russell, S. Selective transduction of proteaserich tumors by matrix-metalloproteinase-targeted retroviral vectors. Gene Ther. 6, 1552-1557 (1999).
    • (1999) Gene Ther. , vol.6 , pp. 1552-1557
    • Peng, K.W.1    Vile, R.2    Cosset, F.L.3    Russell, S.4
  • 38
    • 0030994111 scopus 로고    scopus 로고
    • A gene delivery system activatable by disease-associated matrix metalloproteinases
    • Peng, K.W., Morling, F.J., Cosset, F.L., Murphy, G. & Russell, S.J. A gene delivery system activatable by disease-associated matrix metalloproteinases. Hum. Gene Ther. 8, 729-738 (1997).
    • (1997) Hum. Gene Ther. , vol.8 , pp. 729-738
    • Peng, K.W.1    Morling, F.J.2    Cosset, F.L.3    Murphy, G.4    Russell, S.J.5
  • 39
    • 0034924767 scopus 로고    scopus 로고
    • Lesion-targeted injectable vectors for vascular restenosis
    • Gordon, E.M. et al. Lesion-targeted injectable vectors for vascular restenosis. Hum. Gene Ther. 12, 1277-1287 (2001).
    • (2001) Hum. Gene Ther. , vol.12 , pp. 1277-1287
    • Gordon, E.M.1
  • 40
    • 0035915763 scopus 로고    scopus 로고
    • Systemic administration of a matrix-targeted retroviral vector is efficacious for cancer gene therapy in mice
    • Gordon, E.M. et al. Systemic administration of a matrix-targeted retroviral vector is efficacious for cancer gene therapy in mice. Hum. Gene Ther. 12, 193-204 (2001).
    • (2001) Hum. Gene Ther. , vol.12 , pp. 193-204
    • Gordon, E.M.1
  • 41
    • 0031564336 scopus 로고    scopus 로고
    • Targeting retroviral vectors to vascular lesions by genetic engineering of the MoMLV gp70 envelope protein
    • Hall, F.L. et at. Targeting retroviral vectors to vascular lesions by genetic engineering of the MoMLV gp70 envelope protein. Hum. Gene Ther. 8, 2183-2192 (1997).
    • (1997) Hum. Gene Ther. , vol.8 , pp. 2183-2192
    • Hall, F.L.1
  • 42
    • 0034192369 scopus 로고    scopus 로고
    • Molecular engineering of matrix-targeted retroviral vectors incorporating a surveillance function inherent in von Willebrand factor
    • Hall, F.L. et al. Molecular engineering of matrix-targeted retroviral vectors incorporating a surveillance function inherent in von Willebrand factor. Hum. Gene Ther. 11, 983-993 (2000).
    • (2000) Hum. Gene Ther. , vol.11 , pp. 983-993
    • Hall, F.L.1
  • 43
    • 0032870158 scopus 로고    scopus 로고
    • Genetic capsid modifications allow efficient re-targeting of adenoassociated virus type 2
    • Girod, A. et al. Genetic capsid modifications allow efficient re-targeting of adenoassociated virus type 2. Nature Med. 5, 1052-1056 (1999).
    • (1999) Nature Med. , vol.5 , pp. 1052-1056
    • Girod, A.1
  • 44
    • 0034963928 scopus 로고    scopus 로고
    • Incorporation of tumor-targeting peptides into recombinant adeno-associated virus capsids
    • Grifman, M. et al. Incorporation of tumor-targeting peptides into recombinant adeno-associated virus capsids. Mol. Ther. 3, 964-975 (2001).
    • (2001) Mol. Ther. , vol.3 , pp. 964-975
    • Grifman, M.1
  • 45
    • 0034843445 scopus 로고    scopus 로고
    • Efficient and selective AAV2-mediated gene transfer directed to human vascular endothelial cells
    • Nicklin, S.A. et al. Efficient and selective AAV2-mediated gene transfer directed to human vascular endothelial cells. Mol. Ther. 4, 174-181 (2001).
    • (2001) Mol. Ther. , vol.4 , pp. 174-181
    • Nicklin, S.A.1
  • 46
    • 0036229828 scopus 로고    scopus 로고
    • Adeno-associated virus capsids displaying immunoglobulin-binding domains permit antibody-mediated vector retargeting to specific cell surface receptors
    • Ried, M.U., Girod, A., Leike, K., Buning, H. & Hallek, M. Adeno-associated virus capsids displaying immunoglobulin-binding domains permit antibody-mediated vector retargeting to specific cell surface receptors. J. Virol. 76, 4559-4566 (2002).
    • (2002) J. Virol. , vol.76 , pp. 4559-4566
    • Ried, M.U.1    Girod, A.2    Leike, K.3    Buning, H.4    Hallek, M.5
  • 47
    • 0035121424 scopus 로고    scopus 로고
    • Single-chain antibody displayed on a recombinant measles virus confers entry through the tumor-associated carcinoembryonic antigen
    • Hammond, A.L. et al. Single-chain antibody displayed on a recombinant measles virus confers entry through the tumor-associated carcinoembryonic antigen. J. Virol. 75, 2087-2096 (2001).
    • (2001) J. Virol. , vol.75 , pp. 2087-2096
    • Hammond, A.L.1
  • 48
    • 0036187846 scopus 로고    scopus 로고
    • Novel, chimpanzee serotype 68-based adenoviral vaccine carrier for induction of antibodies to a transgene product
    • Xiang, Z. et al. Novel, chimpanzee serotype 68-based adenoviral vaccine carrier for induction of antibodies to a transgene product. J. Virol. 76, 2667-2675 (2002).
    • (2002) J. Virol. , vol.76 , pp. 2667-2675
    • Xiang, Z.1
  • 49
    • 0035033758 scopus 로고    scopus 로고
    • "Stealth" adenoviruses blunt cell-mediated and humoral immune responses against the virus and allow for significant gene expression upon readministration in the lung
    • Croyle, M.A., Chirmule, N., Zhang, Y. & Wilson, J.M. "Stealth" adenoviruses blunt cell-mediated and humoral immune responses against the virus and allow for significant gene expression upon readministration in the lung. J. Virol. 75, 4792-4801 (2001).
    • (2001) J. Virol. , vol.75 , pp. 4792-4801
    • Croyle, M.A.1    Chirmule, N.2    Zhang, Y.3    Wilson, J.M.4
  • 50
    • 0034632396 scopus 로고    scopus 로고
    • Development of a rapid method for the PEGylation of adenoviruses with enhanced transduction and improved stability under harsh storage conditions
    • Croyle, M.A., Yu, Q.C. & Wilson, J.M. Development of a rapid method for the PEGylation of adenoviruses with enhanced transduction and improved stability under harsh storage conditions. Hum. Gene Ther. 11, 1713-1722 (2000).
    • (2000) Hum. Gene Ther. , vol.11 , pp. 1713-1722
    • Croyle, M.A.1    Yu, Q.C.2    Wilson, J.M.3
  • 51
    • 0035077806 scopus 로고    scopus 로고
    • Polymer-coated adenovirus permits efficient retargeting and evades neutralising antibodies
    • Fisher, K.D. et al. Polymer-coated adenovirus permits efficient retargeting and evades neutralising antibodies. Gene Ther. 8, 341-348 (2001).
    • (2001) Gene Ther. , vol.8 , pp. 341-348
    • Fisher, K.D.1
  • 52
    • 0033230520 scopus 로고    scopus 로고
    • Modification of an adenoviral vector with biologically selected peptides: A novel strategy for gene delivery to cells of choice
    • Romanczuk, H. et al. Modification of an adenoviral vector with biologically selected peptides: a novel strategy for gene delivery to cells of choice. Hum. Gene Ther. 10, 2615-2626 (1999).
    • (1999) Hum. Gene Ther. , vol.10 , pp. 2615-2626
    • Romanczuk, H.1
  • 53
    • 0037088992 scopus 로고    scopus 로고
    • Targeting tumors with non-viral gene delivery systems
    • Ogris, M. & Wagner, E. Targeting tumors with non-viral gene delivery systems. Drug Discov. Today 7, 479-485 (2002).
    • (2002) Drug Discov. Today , vol.7 , pp. 479-485
    • Ogris, M.1    Wagner, E.2
  • 54
    • 0032965399 scopus 로고    scopus 로고
    • Progress towards a synthetic virus for systemic gene therapy
    • MacLachlan, I., Cullis, P. & Graham, R.W. Progress towards a synthetic virus for systemic gene therapy. Curr. Opin. Mol. Ther. 1, 252-259 (1999).
    • (1999) Curr. Opin. Mol. Ther. , vol.1 , pp. 252-259
    • MacLachlan, I.1    Cullis, P.2    Graham, R.W.3
  • 55
    • 0035131596 scopus 로고    scopus 로고
    • Polyethylenimine/DNA complexes shielded by transferrin target gene expression to tumors after systemic application
    • Kircheis, R. et al. Polyethylenimine/DNA complexes shielded by transferrin target gene expression to tumors after systemic application. Gene Ther. 8, 28-40 (2001).
    • (2001) Gene Ther. , vol.8 , pp. 28-40
    • Kircheis, R.1
  • 56
    • 0033544904 scopus 로고    scopus 로고
    • Transferrin-liposome-mediated systemic p53 gene therapy in combination with radiation results in regression of human head and neck cancer xenografts
    • Xu, L., Pirollo, K.F., Tang, W.H., Rait, A. & Chang, E.H. Transferrin-liposome-mediated systemic p53 gene therapy in combination with radiation results in regression of human head and neck cancer xenografts. Hum. Gene Ther. 10, 2941-2952 (1999).
    • (1999) Hum. Gene Ther. , vol.10 , pp. 2941-2952
    • Xu, L.1    Pirollo, K.F.2    Tang, W.H.3    Rait, A.4    Chang, E.H.5
  • 57
    • 0035028214 scopus 로고    scopus 로고
    • Long-circulating vectors for the systemic delivery of genes
    • Fenske, D.B., MacLachlan, I. & Cullis, P.R. Long-circulating vectors for the systemic delivery of genes. Curr. Opin. Mol. Ther. 3, 153-158 (2001).
    • (2001) Curr. Opin. Mol. Ther. , vol.3 , pp. 153-158
    • Fenske, D.B.1    MacLachlan, I.2    Cullis, P.R.3
  • 58
    • 0035980982 scopus 로고    scopus 로고
    • Design and gene delivery activity of modified polyethylenimines
    • Kircheis, R., Wightman, L. & Wagner, E. Design and gene delivery activity of modified polyethylenimines. Adv. Drug Deliv. Rev. 53, 341-358 (2001).
    • (2001) Adv. Drug Deliv. Rev. , vol.53 , pp. 341-358
    • Kircheis, R.1    Wightman, L.2    Wagner, E.3
  • 59
    • 0036021898 scopus 로고    scopus 로고
    • Tumor-targeted gene delivery of tumor necrosis factor-α induces tumor necrosis and tumor regression without systemic toxicity
    • Kircheis, R. et al. Tumor-targeted gene delivery of tumor necrosis factor-α induces tumor necrosis and tumor regression without systemic toxicity. Cancer Gene Ther. 9, 673-680 (2002).
    • (2002) Cancer Gene Ther. , vol.9 , pp. 673-680
    • Kircheis, R.1
  • 60
    • 0032938324 scopus 로고    scopus 로고
    • PEGylated DNA/transferrin-PEI complexes: Reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery
    • Ogris, M., Brunner, S., Schuller, S., Kircheis, R. & Wagner, E. PEGylated DNA/transferrin-PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery. Gene Ther. 6, 595-605 (1999).
    • (1999) Gene Ther. , vol.6 , pp. 595-605
    • Ogris, M.1    Brunner, S.2    Schuller, S.3    Kircheis, R.4    Wagner, E.5
  • 61
    • 0035094928 scopus 로고    scopus 로고
    • Pulmonary collectins and innate host defense of the lung
    • LeVine, A.M. & Whitsett, J.A. Pulmonary collectins and innate host defense of the lung. Microbes Infect. 3, 161-166 (2001).
    • (2001) Microbes Infect. , vol.3 , pp. 161-166
    • LeVine, A.M.1    Whitsett, J.A.2
  • 62
    • 0029014280 scopus 로고
    • Collectins and viral infection
    • Malhotra, R. & Sim, R.B. Collectins and viral infection. Trends Microbiol. 3, 240-244 (1995).
    • (1995) Trends Microbiol. , vol.3 , pp. 240-244
    • Malhotra, R.1    Sim, R.B.2
  • 63
    • 0031710735 scopus 로고    scopus 로고
    • Antiviral activity of bovine collectins against rotaviruses
    • Reading, P.C., Holmskov, U. & Anders, E.M. Antiviral activity of bovine collectins against rotaviruses. J. Gen. Virol. 79, 2255-2263 (1998).
    • (1998) J. Gen. Virol. , vol.79 , pp. 2255-2263
    • Reading, P.C.1    Holmskov, U.2    Anders, E.M.3
  • 64
    • 0030879806 scopus 로고    scopus 로고
    • Collectin-mediated antiviral host defense of the lung: Evidence from influenza virus infection of mice
    • Reading, P.C., Morey, L.S., Crouch, E.C. & Anders, E.M. Collectin-mediated antiviral host defense of the lung: evidence from influenza virus infection of mice. J. Virol. 71, 8204-8212 (1997).
    • (1997) J. Virol. , vol.71 , pp. 8204-8212
    • Reading, P.C.1    Morey, L.S.2    Crouch, E.C.3    Anders, E.M.4
  • 65
    • 0034682892 scopus 로고    scopus 로고
    • Genes expressed in human tumor endothelium
    • St Croix, B. et al. Genes expressed in human tumor endothelium. Science 289, 1197-1202 (2000).
    • (2000) Science , vol.289 , pp. 1197-1202
    • St Croix, B.1
  • 66
    • 0034948066 scopus 로고    scopus 로고
    • Phage display of adenovirus type 5 fiber knob as a tool for specific ligand selection and validation
    • Pereboev, A., Pereboeva, L. & Curiel, D.T. Phage display of adenovirus type 5 fiber knob as a tool for specific ligand selection and validation. J. Virol. 75, 7107-7113 (2001).
    • (2001) J. Virol. , vol.75 , pp. 7107-7113
    • Pereboev, A.1    Pereboeva, L.2    Curiel, D.T.3
  • 67
    • 0034688217 scopus 로고    scopus 로고
    • Targeting human T cells by retroviral vectors displaying antibody domains selected from a phage display library
    • Engelstadter, M. et al. Targeting human T cells by retroviral vectors displaying antibody domains selected from a phage display library. Hum. Gene Ther. 11, 293-303 (2000).
    • (2000) Hum. Gene Ther. , vol.11 , pp. 293-303
    • Engelstadter, M.1
  • 68
    • 0031787970 scopus 로고    scopus 로고
    • In vivo selection of protease cleavage sites from retrovirus display libraries
    • Buchholz, C.J. et al. In vivo selection of protease cleavage sites from retrovirus display libraries. Nature Biotechnol. 16, 951-954 (1998).
    • (1998) Nature Biotechnol. , vol.16 , pp. 951-954
    • Buchholz, C.J.1
  • 69
    • 0012517578 scopus 로고    scopus 로고
    • Genetic engineering of targeted retroviral vectors
    • eds. Curiel, D.T. & Douglas, J.T., Wiley-Liss, Hoboken, NJ
    • Gordon, E.M., Hall, F.L., Beart, R.W. & Anderson, W.F. Genetic engineering of targeted retroviral vectors. in Vector Targeting for Therapeutic Gene Delivery (eds. Curiel, D.T. & Douglas, J.T.) 293-320 (Wiley-Liss, Hoboken, NJ, 2002).
    • (2002) Vector Targeting for Therapeutic Gene Delivery , pp. 293-320
    • Gordon, E.M.1    Hall, F.L.2    Beart, R.W.3    Anderson, W.F.4


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