Cell-specific targeting of sindbis virus vectors displaying IgG-binding domains of protein a

Nature Biotechnology

Volumn 15, Issue 8, 1997, Pages 763-767

  Ohno, Kouichi ^a   Sawai, Keisuke ^a   Iijima, Yasushi ^a   Levin, Brandi ^a   Meruelo, Daniel ^a  

^a NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Alphavirus; Gene therapy vector; Protein A; Targeting

Indexed keywords

IMMUNOGLOBULIN BINDING FACTOR; IMMUNOGLOBULIN G;

ARTICLE; CHIMERA; EXPRESSION VECTOR; GENE THERAPY; GENETIC RECOMBINATION; HAMSTER; LYMPHOBLASTOID CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN TARGETING; SINDBIS VIRUS; VIRUS DNA CELL DNA INTERACTION;

ANIMALS; ANTIBODIES, MONOCLONAL; BETA-GALACTOSIDASE; BINDING SITES; CRICETINAE; DRUG DELIVERY SYSTEMS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HELA CELLS; HUMANS; IMMUNOGLOBULIN G; MEMBRANE GLYCOPROTEINS; MICE; RECOMBINANT FUSION PROTEINS; SINDBIS VIRUS; STAPHYLOCOCCAL PROTEIN A; TUMOR CELLS, CULTURED; VIRAL ENVELOPE PROTEINS; VIRION;

ALPHAVIRUS; CRICETINAE; INSECTA; SINDBIS VIRUS; VERTEBRATA;

EID: 0030835821     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt0897-763     Document Type: Article

References (25)

1. Strauss, J.H. and Strauss, E.G. 1994. The alphaviruses: gene expression, replication, and evolution. Microbiol. Rev. 58:491-562.
2. Liljeström, P. and Garoff, H. 1991. A new generation of animal cell expression vectors based on the Semliki Forest virus replicon. Biotechnology 9:1356-1361.
3. Bredenbeek, P. and Rice, C.M. 1992. Animal RNA virus expression systems. Semin. Virol. 3:297-310.
4. Xiong, C., Levis, R., Shen, P., Schlesinger, S., Rice, C.M., and Huang, H.V. 1989. Sindbis virus: an efficient, broad host range vector for gene expression in animal cells. Science 243:1188-1191.
5. Wang, K.-S., Kuhn, R.J., Strauss, E.G., Ou, S., and Strauss, J.H. 1992. High-affinity laminin receptor is a receptor for Sindbis virus in mammalian cells. J. Virol. 66:4992-5001.
6. Stanley, J., Cooper, S.J., and Griffin, D.E. 1985. Alphavirus neurovirulence: monoclonal antibodies discriminating wild-type from neuroadapted Sindbis virus. J. Virol. 56:110-119.
7. Olmsted, R.A., Meyer, W.J., and Johnston, R.E. 1986. Characterization of Sindbis virus epitopes important for penetration in cell culture and pathogenesis in animals. Virology 148:245-254.
8. Polo, J.M., Davis, N.L, Rice, C.M., Huang, H.V, and Johnston, R.E. 1988. Molecular analysis of Sindbis virus pathogenesis in neonatal mice by using virus recombinants constructed in vitro. J. Virol. 62:2124-2133.
9. Lustig, S., Jackson, A.C., Hahn, C.S., Griffin, D.E., Strauss, E.G., and Strauss, J.H. 1988. Molecular basis of Sindbis virus neurovirulence in mice. J. Virol. 62:2329-2336.
10. Dubuisson, J. and Rice, C.M. 1993. Sindbis virus attachment: isolation and characterization of mutants with impaired binding to vertebrate cells. J. Virol. 67:3363-3374.
11. Russell, S.J., Hawkins, R.E., and Winter, G. 1993. Retroviral vectors displaying functional antibody fragments. Nucleic Acids Res. 21:1081-1085.
12. Somia, N.V., Zoppé, M., and Verma, I.M. 1995. Generation of targeted retroviral vectors by using single-chain variable fragment: An approach to in vivo gene delivery. Proc. Natl. Acad. Sci. USA 92:7570-7574.
13. Marin, M., Noël, D., Valsesia-Wittman, S., Brockly, F., Etienne-Julan, M., Russel, S., et al. 1996. Targeted infection of human cells via major histocompatibility complex class I molecules by moloney murine leukemia virus-derived viruses displaying single-chain antibody fragment-envelope fusion proteins. J. Virol. 70:2957-2962.
14. Kasahara, N., Dozy, A.M., and Kan, Y.W. 1994. Tissue-specific targeting of retroviral vectors through ligand-receptor interactions. Science 266:1373-1376.
15. Surolia, A., Pain, D., and Khan, M.I. 1982. Protein A: nature’s universal anti-antibody Trends Biochem. Sci. 7:74-76.
16. Bredenbeek, P.J., Frolov, I., Rice, C.M. and Schlesinger, S. 1993. Sindbis virus expression vectors: packaging of RNA replicons by using defective helper RNAs. J. Virol. 67:6439-6446.
17. Nilsson, B., Moks, T, Jansson, B., Abrahmsén, L, Elmblad, A., Holmgren, E., et al. 1987. A synthetic IgG-binding domain based on staphylococcal protein A. Protein Eng. 1:107-113.
18. Douglas, J.T., Rogers, B.E., Rosenfeld, M.E., Michael, S.I., and Curiel, M.F.D.T. 1996. Targeted gene delivery by tropism-modified adenoviral vectors. Nature Biotechnology 14:1574-1578.
19. Rosenfeld, M.A., Siegfried, W., Yoshimura, D., Yoneyama, K., Fukayama, M., Stier, L.E., et al. 1991. Adenovirus-mediated transfer of a recombinant anti-antitrypsin gene to the lung epithelium in vivo. Science 252:431-434.
20. Levine, B., Huang, Q., Isaacs, J.T., Reed, J.C, Griffin, D.E., and Hardwick, J.M. 1993. Conversion of lytic to persistent alphavirus infection by the bcl-2 cellular oncogene. Nature 361:739-742.
21. Levine, B. and Griffin, D.E. 1992. Persistence of viral RNA in mouse brains after recovery from acute alphavirus encephalitis. J. Virol. 66:6429-6435.
22. Wang, K.S., Schmaljohn, A.L., Kuhn, R.J., and Strauss, J.H. 1991. Antiidiotypic antibodies as probes for the Sindbis virus receptor. Virology 181:694-702.
23. Ubol, S. and Griffin, D.E. 1991. Identification of a putative alphavirus receptor on mouse neural cells. J. Virol. 65:6913-6921.
24. Löwenadler, B., Jansson, B., Paleus, S., Holmgren, E., Nilsson, B., Moks, T., et al. 1987. A gene fusion system for generating antibodies against short peptides. Gene 58:87-97.
25. Fiering, S.N., Roederer, M., Nolan, G.P., Micklem, D.R., Parks, D.R., and Herzenberg, L.A. 1991. Improved FACS-Gal: Flow cytometric analysis and sorting of viable eukaryotlc cells expressing reporter gene construction. Cytometry 12:291-301.