The Role of Leucine 191 of Escherichia coli Uracil DNA Glycosylase in the Formation of a Highly Stable Complex with the Substrate Mimic, Ugi, and in Uracil Excision from the Synthetic Substrates

Journal of Biological Chemistry

Volumn 276, Issue 20, 2001, Pages 17324-17331

  Handa, Priya ^a   Roy, Sudipta ^a   Varshney, Umesh ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CATALYST ACTIVITY; COMPLEXATION; DNA; ENZYME KINETICS; ESCHERICHIA COLI; MUTAGENESIS; PHYSIOLOGY;

URACILS;

ENZYMES;

LEUCINE; PEPTIDE; PROTEIN MIMIC; PROTEIN UGI; UNCLASSIFIED DRUG; URACIL; URACIL DNA GLYCOSYLTRANSFERASE; DNA GLYCOSYLTRANSFERASE; ENZYME INHIBITOR; GLYCOSIDASE; INTERCALATING AGENT; OLIGODEOXYRIBONUCLEOTIDE; RECOMBINANT PROTEIN; URACIL DNA GLYCOSIDASE; URACIL DNA GLYCOSYLASE INHIBITOR, VIRUS; URACIL-DNA GLYCOSYLASE INHIBITOR, VIRUS; UREA; VIRUS PROTEIN;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BACTERIOPHAGE; COMPLEX FORMATION; DNA REPAIR; DNA STRAND; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME STABILITY; ENZYME SUBSTRATE; ENZYME SUBSTRATE COMPLEX; ENZYME SYNTHESIS; ESCHERICHIA COLI; EXCISION REPAIR; GENE MUTATION; NONHUMAN; PEPTIDE ANALYSIS; PRIORITY JOURNAL; PROTEIN MOTIF; STRUCTURE ANALYSIS; WILD TYPE; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; GENETICS; KINETICS; METABOLISM; PROTEIN SECONDARY STRUCTURE; SPECTROFLUOROMETRY;

ANIMALIA; ESCHERICHIA COLI; NEGIBACTERIA; STAPHYLOCOCCUS PHAGE 187;

AMINO ACID SUBSTITUTION; DNA GLYCOSYLASES; DNA REPAIR; ENZYME INHIBITORS; ENZYME STABILITY; ESCHERICHIA COLI; INTERCALATING AGENTS; KINETICS; LEUCINE; MODELS, MOLECULAR; N-GLYCOSYL HYDROLASES; OLIGODEOXYRIBONUCLEOTIDES; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; SPECTROMETRY, FLUORESCENCE; URACIL; URACIL-DNA GLYCOSIDASE; UREA; VIRAL PROTEINS;

EID: 0035907352     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M011166200     Document Type: Article

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