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Abrogation of bronchial eosinophilic inflammation and airway hyperreactivity in signal transducer and activator of transcription (STAT)6-deficient mice
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Signal transducer and activator of transcription 6 controls chemokine production and T helper cell type 2 cell trafficking in allergic pulmonary inflammation
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Mathew, A., J. A. MacLean, E. DeHaan, A. M. Tager, F. H. Y. Green, and A. D. Luster. 2001. Signal transducer and activator of transcription 6 controls chemokine production and T helper cell type 2 cell trafficking in allergic pulmonary inflammation. J. Exp. Med. 193:1087.
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IL-13-induced airway hyperreactivity during respiratory syncytial virus infection is STAT6 dependent
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STAT6 is required for IL-4-induced germline Ig gene transcription and switch recombination
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T cell receptor complementarity determining region 3 length analysis reveals the absence of a characteristic public T cell repertoire in neonatal tolerance: The response in the "tolerant" mouse within the residual repertoire is quantitatively similar but qualitatively different
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Failure to induce neonatal tolerance in mice that lack both IL-4 and IL-13 but not in those that lack IL-4 alone
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Inoue, Y., B. T. Konieczny, M. E. Wagener, A. N. McKenzie, and F. G. Lakkis. 2001. Failure to induce neonatal tolerance in mice that lack both IL-4 and IL-13 but not in those that lack IL-4 alone. J. Immunol. 167:1125.
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+ T cells: IL-4 and IFN-γ have opposing effects, while TGF-β positively regulates its own production
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+ T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines
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Orally induced peripheral nonresponsiveness is maintained in the absence of functional Th1 or Th2 cells
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