메뉴 건너뛰기




Volumn 4, Issue 7-8, 2002, Pages 637-653

Iron in neurodegenerative disorders

Author keywords

Brain iron accumulation; Neurodegenerative disorders; Proteins of iron metabolism

Indexed keywords

IRON; RADICAL;

EID: 0036853879     PISSN: 10298428     EISSN: None     Source Type: Journal    
DOI: 10.1080/1029842021000045444     Document Type: Review
Times cited : (31)

References (241)
  • 1
    • 0034733635 scopus 로고    scopus 로고
    • "A novel mammalian iron-regulated protein involved in intracellular iron metabolism"
    • Abboud, S. and Haile, D.J. (2000) "A novel mammalian iron-regulated protein involved in intracellular iron metabolism", J. Biol. Chem. 26, 19906-19912.
    • (2000) J. Biol. Chem. , vol.26 , pp. 19906-19912
    • Abboud, S.1    Haile, D.J.2
  • 2
    • 0033838364 scopus 로고    scopus 로고
    • "Iron dependent self-assembly of recombinant yeast frataxin. Implications for Friedreich Ataxia"
    • Adamec, J., Rusnak, F., Owen, W.G., Naylor, S., Benson, L.M., Gacy, A.M. and Isaya, G. (2000) "Iron dependent self-assembly of recombinant yeast frataxin. Implications for Friedreich Ataxia", Am. J. Hum. Genet. 67, 549-562.
    • (2000) Am. J. Hum. Genet. , vol.67 , pp. 549-562
    • Adamec, J.1    Rusnak, F.2    Owen, W.G.3    Naylor, S.4    Benson, L.M.5    Gacy, A.M.6    Isaya, G.7
  • 5
    • 0032920837 scopus 로고    scopus 로고
    • "Mutation of a putative mitochondrial iron tranpsorter gene (ABC7) in X-linked sideroblastic anemia and ataxia (XLSA/A)"
    • Allikmets, R., Raskind, W.H., Hutchinson, A., Schueck, N.D., Dean, M. and Koeller, D.M. (1999) "Mutation of a putative mitochondrial iron tranpsorter gene (ABC7) in X-linked sideroblastic anemia and ataxia (XLSA/A)", Hum. Mol. Genet. 8, 743-749.
    • (1999) Hum. Mol. Genet. , vol.8 , pp. 743-749
    • Allikmets, R.1    Raskind, W.H.2    Hutchinson, A.3    Schueck, N.D.4    Dean, M.5    Koeller, D.M.6
  • 6
    • 0031721278 scopus 로고    scopus 로고
    • "Lewy body in neurodegeneration with brain iron accumulation type 1 is immunoreactive for alpha-synuclein"
    • Arawaka, S., Saito, Y., Murayma, S. and Mori, H. (1998) "Lewy body in neurodegeneration with brain iron accumulation type 1 is immunoreactive for alpha-synuclein", Neurology 51, 887-889.
    • (1998) Neurology , vol.51 , pp. 887-889
    • Arawaka, S.1    Saito, Y.2    Murayma, S.3    Mori, H.4
  • 7
    • 0031715398 scopus 로고    scopus 로고
    • "NACP/alpha-synuclein immunoreactivity in fibrillary components of neuronal and oligodendroglial cytoplasmatic inclusions in the pontine nuclei in multiple system atrophy"
    • Arima, K., Ueda, K., Sunohara, N., Arakawa, K., Hirai, S., Nakamura, M., Tonozuka-Uehara, H. and Kawai, M. (1998) "NACP/alpha-synuclein immunoreactivity in fibrillary components of neuronal and oligodendroglial cytoplasmatic inclusions in the pontine nuclei in multiple system atrophy", Acta Neuropathol. (Berl.) 96, 439-444.
    • (1998) Acta Neuropathol. (Berl.) , vol.96 , pp. 439-444
    • Arima, K.1    Ueda, K.2    Sunohara, N.3    Arakawa, K.4    Hirai, S.5    Nakamura, M.6    Tonozuka-Uehara, H.7    Kawai, M.8
  • 8
    • 0025878817 scopus 로고
    • "Structural and functional studies of human ferritin H and L chains"
    • Lenfant, A.A., Manucci, C.L. and Sixma, P.M., eds, (Karger, Basel)
    • Arosio, P., Levi, S., Santambrogio, P., Cozzi, A., Luzaggo, A., Cesareni, G. and Albertini, A. (1991) "Structural and functional studies of human ferritin H and L chains", In: Lenfant, A.A., Manucci, C.L. and Sixma, P.M., eds, Biotechnology of Plasma Proteins, (Karger, Basel), pp. 127-131.
    • (1991) Biotechnology of Plasma Proteins , pp. 127-131
    • Arosio, P.1    Levi, S.2    Santambrogio, P.3    Cozzi, A.4    Luzaggo, A.5    Cesareni, G.6    Albertini, A.7
  • 9
    • 0031979898 scopus 로고    scopus 로고
    • "Iron and copper transport in yeast and its relevance to human disease"
    • Askwith, C. and Kaplan, J. (1998) "Iron and copper transport in yeast and its relevance to human disease", TIBS 23, 135-138.
    • (1998) TIBS , vol.23 , pp. 135-138
    • Askwith, C.1    Kaplan, J.2
  • 10
    • 0033534589 scopus 로고    scopus 로고
    • "Ceruloplasmin ferroxidase activity stimulates cellular iron uptake by a trivalent cation-specific transport mechanism"
    • Attieh, Z.K., Mukhopadhyay, C.K., Seshadri, V., Tripoulas, N.A. and Fox, P.L. (1999) "Ceruloplasmin ferroxidase activity stimulates cellular iron uptake by a trivalent cation-specific transport mechanism", J. Biol. Chem. 274, 1116-1123.
    • (1999) J. Biol. Chem. , vol.274 , pp. 1116-1123
    • Attieh, Z.K.1    Mukhopadhyay, C.K.2    Seshadri, V.3    Tripoulas, N.A.4    Fox, P.L.5
  • 12
    • 0005652488 scopus 로고    scopus 로고
    • "MRI evaluation of basal ganglia ferritin iron and neurotoxicity in Alzheimer's and Huntington's disease"
    • Bartzokis, G. and Tishler, T.A. (2000) "MRI evaluation of basal ganglia ferritin iron and neurotoxicity in Alzheimer's and Huntington's disease", Cell Mol. Biol. 46, 821-833.
    • (2000) Cell Mol. Biol. , vol.46 , pp. 821-833
    • Bartzokis, G.1    Tishler, T.A.2
  • 15
    • 0032504710 scopus 로고    scopus 로고
    • "Mitochondrial dysfunction in neurodegenerative diseases"
    • Beal M.F. (1998) "Mitochondrial dysfunction in neurodegenerative diseases", Biochim. Biophys. Acta 1366, 211-223.
    • (1998) Biochim. Biophys. Acta , vol.1366 , pp. 211-223
    • Beal, M.F.1
  • 16
    • 0035122450 scopus 로고    scopus 로고
    • "Frataxin: Its role in iron metabolism and the pathogenesis of Friedreich's ataxia"
    • Becker, E. and Des Richardson, R. (2001) "Frataxin: its role in iron metabolism and the pathogenesis of Friedreich's ataxia", Int. J. Biochem. Cell Biol. 33, 1-10.
    • (2001) Int. J. Biochem. Cell Biol. , vol.33 , pp. 1-10
    • Becker, E.1    Des Richardson, R.2
  • 17
    • 0028869760 scopus 로고
    • "Degeneration of substantia nigra in chronic Parkinson's disease visualized by transcranial color-coded real-time sonography"
    • Becker, G., Seufert, J., Bogdahn, U., Reichmann, H. and Reiners, K. (1995) "Degeneration of substantia nigra in chronic Parkinson's disease visualized by transcranial color-coded real-time sonography", Neurology 45, 182-184.
    • (1995) Neurology , vol.45 , pp. 182-184
    • Becker, G.1    Seufert, J.2    Bogdahn, U.3    Reichmann, H.4    Reiners, K.5
  • 18
    • 0034329310 scopus 로고    scopus 로고
    • "Human ABC7 transporter: Gene structure and mutation causing X-linked sideroblastic anemia with ataxia with disruption of cytosolic iron-sulfur protein maturation"
    • Bekri, S., Kispal, G., Lange, H., Fitzsimons, E., Tolmie, J., Lill, R. and Bishop, D.F. (2000) "Human ABC7 transporter: gene structure and mutation causing X-linked sideroblastic anemia with ataxia with disruption of cytosolic iron-sulfur protein maturation", Blood 96, 3256-3264.
    • (2000) Blood , vol.96 , pp. 3256-3264
    • Bekri, S.1    Kispal, G.2    Lange, H.3    Fitzsimons, E.4    Tolmie, J.5    Lill, R.6    Bishop, D.F.7
  • 19
    • 0026040282 scopus 로고
    • "Iron-melanin interaction and lipid peroxidation: Implications for Parkinson's disease"
    • Ben-Shachar, D., Riederer, P. and Youdim, M.B. (1991) "Iron-melanin interaction and lipid peroxidation: implications for Parkinson's disease", J. Neurochem. 57, 1609-1614.
    • (1991) J. Neurochem. , vol.57 , pp. 1609-1614
    • Ben-Shachar, D.1    Riederer, P.2    Youdim, M.B.3
  • 22
    • 0034935922 scopus 로고    scopus 로고
    • "Substantia nigra hyperechogenicity on transcranial ultrasound-state marker for Parkinson's disease and impact on disease course"
    • Berg, D., Siefker, C. and Becker, G. (2001a) "Substantia nigra hyperechogenicity on transcranial ultrasound-state marker for Parkinson's disease and impact on disease course", J. Neurol. 248, 684-689.
    • (2001) J. Neurol. , vol.248 , pp. 684-689
    • Berg, D.1    Siefker, C.2    Becker, G.3
  • 25
    • 0033512348 scopus 로고    scopus 로고
    • "New perspectives on iron: An introduction"
    • Boldt, D.H. (1999) "New perspectives on iron: an introduction", Am. J. Med. Sci. 318, 207-212.
    • (1999) Am. J. Med. Sci. , vol.318 , pp. 207-212
    • Boldt, D.H.1
  • 26
    • 0033597299 scopus 로고    scopus 로고
    • "Reduced ferroxidase activity in the cerebrospinal fluid from patients with Parkinson's disease"
    • Boll, M.-C., Sotelo, J., Otero, E., Alcaraz-Zubeldia, M. and Rios, C. (1999) "Reduced ferroxidase activity in the cerebrospinal fluid from patients with Parkinson's disease", Neurosci. Lett. 265, 155-158.
    • (1999) Neurosci. Lett. , vol.265 , pp. 155-158
    • Boll, M.-C.1    Sotelo, J.2    Otero, E.3    Alcaraz-Zubeldia, M.4    Rios, C.5
  • 28
    • 0029019616 scopus 로고
    • "Restriction polymorphisms of the ceruloplasmin gene on chromosome 3"
    • Bost, M., Berkaw, M., McBride, O.W., Chazot, G. and Arnaud, P. (1995) "Restriction polymorphisms of the ceruloplasmin gene on chromosome 3", Hum. Genet. 96, 239-240.
    • (1995) Hum. Genet. , vol.96 , pp. 239-240
    • Bost, M.1    Berkaw, M.2    McBride, O.W.3    Chazot, G.4    Arnaud, P.5
  • 29
    • 0030739637 scopus 로고    scopus 로고
    • "Transport of iron in the blood-brain-cerebrospinal fluid system"
    • Bradbury, M.W.B. (1997) "Transport of iron in the blood-brain-cerebrospinal fluid system", J. Neurochem. 69, 443-454.
    • (1997) J. Neurochem. , vol.69 , pp. 443-454
    • Bradbury, M.W.B.1
  • 31
    • 0034961104 scopus 로고    scopus 로고
    • "Amyotrophic lateral sclerosis: Pathogenesis"
    • Brown, R.H. and Robberecht, W. (2001) "Amyotrophic lateral sclerosis: pathogenesis", Semin. Neurol. 21, 131-139.
    • (2001) Semin. Neurol. , vol.21 , pp. 131-139
    • Brown, R.H.1    Robberecht, W.2
  • 32
    • 0001670657 scopus 로고
    • "Huntington's chorea: Historical, clinical, and laboratory analysis"
    • Vinken P.J. and Bruyn, G.W., eds
    • Bruyn, G.W. (1968) "Huntington's chorea: historical, clinical, and laboratory analysis", In: Vinken, P.J. and Bruyn, G.W., eds, Handbook of Clinical Neurology Vol. 6, pp. 379-396.
    • (1968) Handbook of Clinical Neurology , vol.6 , pp. 379-396
    • Bruyn, G.W.1
  • 34
    • 0035229653 scopus 로고    scopus 로고
    • "Specific metal-catalysed protein reactions in chronic degenerative disorders of ageing: Focus on Alzheimer's disease and age-related cataracts"
    • Bush, A.I. and Goldstein, L.E. (2001) "Specific metal-catalysed protein reactions in chronic degenerative disorders of ageing: focus on Alzheimer's disease and age-related cataracts", Novartis Found. Symp. 235, 26-43.
    • (2001) Novartis Found. Symp. , vol.235 , pp. 26-43
    • Bush, A.I.1    Goldstein, L.E.2
  • 35
    • 0025754836 scopus 로고
    • "Expression of genes for the ferritin H and L subunits in rat liver and heart"
    • Cairo, G., Rappocciolo, E., Tacchini, L. and Schiaffonati, L. (1991) "Expression of genes for the ferritin H and L subunits in rat liver and heart", Biochem. J. 275, 813-816.
    • (1991) Biochem. J. , vol.275 , pp. 813-816
    • Cairo, G.1    Rappocciolo, E.2    Tacchini, L.3    Schiaffonati, L.4
  • 37
    • 9844222853 scopus 로고    scopus 로고
    • "Frataxin is reduced in Friedreich's ataxia patients and is associated with mitochondrial membranes"
    • Campuzano, V., Montermini, L., Lutz, Y., et al., (1997) "Frataxin is reduced in Friedreich's ataxia patients and is associated with mitochondrial membranes", Hum. Mol. Genet. 61, 1771-1780.
    • (1997) Hum. Mol. Genet. , vol.61 , pp. 1771-1780
    • Campuzano, V.1    Montermini, L.2    Lutz, Y.3
  • 38
    • 0033006576 scopus 로고    scopus 로고
    • "Is increased redox-active iron in Alzheimer disease a failure of the copper-binding protein ceruloplasmin?"
    • Castellani, R.J., Smith, M.A., Nunomura, A., Harris, P.L. and Perry, G. (1999) "Is increased redox-active iron in Alzheimer disease a failure of the copper-binding protein ceruloplasmin?" Free Radic. Biol. Med., 26, 1508-1512.
    • (1999) Free Radic. Biol. Med. , vol.26 , pp. 1508-1512
    • Castellani, R.J.1    Smith, M.A.2    Nunomura, A.3    Harris, P.L.4    Perry, G.5
  • 39
    • 0027157364 scopus 로고
    • "MR and human postmortem brain tissue: Correlation between T2 and assays of iron and ferritin in Parkinson and Huntington disease"
    • Chen, J.C., Hardy, P.A., Kucharczyk, W., Clauberg, M., Joshi, J.G., Vourlas, A., Dhar, M. and Henkelman, R.M. (1993) "MR and human postmortem brain tissue: correlation between T2 and assays of iron and ferritin in Parkinson and Huntington disease", AJNR 14, 275-281.
    • (1993) AJNR , vol.14 , pp. 275-281
    • Chen, J.C.1    Hardy, P.A.2    Kucharczyk, W.3    Clauberg, M.4    Joshi, J.G.5    Vourlas, A.6    Dhar, M.7    Henkelman, R.M.8
  • 40
    • 0034851578 scopus 로고    scopus 로고
    • "Iron overload, oxidative stress, and axonal dystrophy in brain disorders"
    • Chiueh, C.C. (2001) "Iron overload, oxidative stress, and axonal dystrophy in brain disorders", Pediatr. Neurol. 25, 138-147.
    • (2001) Pediatr. Neurol. , vol.25 , pp. 138-147
    • Chiueh, C.C.1
  • 41
    • 0035666597 scopus 로고    scopus 로고
    • "Mechanisms of neurodegeneration in amyotrophic lateral sclerosis"
    • Cluskey, S. and Ramsden, D.B. (2001) "Mechanisms of neurodegeneration in amyotrophic lateral sclerosis", J. Clin. Pathol.: Mol. Pathol. 54, 386-392.
    • (2001) J. Clin. Pathol.: Mol. Pathol. , vol.54 , pp. 386-392
    • Cluskey, S.1    Ramsden, D.B.2
  • 42
    • 0024444872 scopus 로고
    • "Brain iron in progressive supranuclear palsy: Clinical, magnetic resonance imaging, and neuropathological findings"
    • Coffey, C.E., Alston, S., Heinz, E.R. and Burger, P.C. (1989) "Brain iron in progressive supranuclear palsy: clinical, magnetic resonance imaging, and neuropathological findings", J. Neuropsychiatry Clin. Neurosci. 1, 400-404.
    • (1989) J. Neuropsychiatry Clin. Neurosci. , vol.1 , pp. 400-404
    • Coffey, C.E.1    Alston, S.2    Heinz, E.R.3    Burger, P.C.4
  • 43
    • 0003066274 scopus 로고    scopus 로고
    • "Evidence for iron mismanagement in the brain in neurological disorders"
    • Connor, J., ed, (Plenum Press, New York)
    • Connor, J. (1997) "Evidence for iron mismanagement in the brain in neurological disorders", In: Connor, J., ed, Metals and Oxidative Damage in Neurological Disorders (Plenum Press, New York), pp. 23-39.
    • (1997) Metals and Oxidative Damage in Neurological Disorders , pp. 23-39
    • Connor, J.1
  • 44
    • 0026635457 scopus 로고
    • "Iron regulation in the brain: Histochemical, biochemical, and molecular considerations"
    • Connor, J.R. and Benkovic, S.A. (1992) "Iron regulation in the brain: histochemical, biochemical, and molecular considerations", Ann. Neurol. 32, S51-S61.
    • (1992) Ann. Neurol. , vol.32
    • Connor, J.R.1    Benkovic, S.A.2
  • 45
    • 0026590705 scopus 로고
    • "The regional distribution of iron and iron regulatory proteins in the brain in aging and Alzheimer's disease"
    • Connor, J.R., Snyder, B.S., Beard, J.L., Fine, R.E. and Mufson, E.J. (1992) "The regional distribution of iron and iron regulatory proteins in the brain in aging and Alzheimer's disease", J. Neurosci. Res. 31, 327-335.
    • (1992) J. Neurosci. Res. , vol.31 , pp. 327-335
    • Connor, J.R.1    Snyder, B.S.2    Beard, J.L.3    Fine, R.E.4    Mufson, E.J.5
  • 46
    • 0031800225 scopus 로고    scopus 로고
    • "Imbalances of trace elements related to oxidative damage in Alzheimer's disease brain"
    • Cornett, C.R., Markesbery, W.R. and Ehmann, W.D. (1998) "Imbalances of trace elements related to oxidative damage in Alzheimer's disease brain", Neurotoxicology 19, 339-345.
    • (1998) Neurotoxicology , vol.19 , pp. 339-345
    • Cornett, C.R.1    Markesbery, W.R.2    Ehmann, W.D.3
  • 49
    • 0032414310 scopus 로고    scopus 로고
    • "Identification of a human mitochondrial ABC transporter, the functional orthologue of yeast Atm1p"
    • Csere, P., Lill, R. and Kispal, G. (1998) "Identification of a human mitochondrial ABC transporter, the functional orthologue of yeast Atm1p", FEBS Lett. 441, 266-270.
    • (1998) FEBS Lett. , vol.441 , pp. 266-270
    • Csere, P.1    Lill, R.2    Kispal, G.3
  • 54
    • 0029586715 scopus 로고
    • "Evolution of ATP-binding cassette transporter genes"
    • Dean, M. and Allikmets, R. (1995) "Evolution of ATP-binding cassette transporter genes", Curr. Opin. Genet. Dev. 5, 779-785.
    • (1995) Curr. Opin. Genet. Dev. , vol.5 , pp. 779-785
    • Dean, M.1    Allikmets, R.2
  • 55
    • 0030297178 scopus 로고    scopus 로고
    • "Copper, iron, and zinc imbalances in severely degenerated bran regions in Alzheimer's disease: Possible relation to oxidative stress"
    • Deibel, M.A., Ehmann, W.D. and Markesbery, W.R. (1996) "Copper, iron, and zinc imbalances in severely degenerated bran regions in Alzheimer's disease: possible relation to oxidative stress", J. Neurol. Sci. 143, 137-142.
    • (1996) J. Neurol. Sci. , vol.143 , pp. 137-142
    • Deibel, M.A.1    Ehmann, W.D.2    Markesbery, W.R.3
  • 56
    • 0033709765 scopus 로고    scopus 로고
    • "Clinical report of three patients with hereditary hemochromatosis and movement disorders"
    • Demarquay, G., Setiey, A., Morel, Y., Trepo, C., Chazot, G. and Broussolle, E. (2000) "Clinical report of three patients with hereditary hemochromatosis and movement disorders", Mov. Disord. 15, 1204-1209.
    • (2000) Mov. Disord. , vol.15 , pp. 1204-1209
    • Demarquay, G.1    Setiey, A.2    Morel, Y.3    Trepo, C.4    Chazot, G.5    Broussolle, E.6
  • 57
    • 0024356620 scopus 로고
    • "Increased nigral iron content and alterations in other metal ions occuring in brain in Parkinson's disease"
    • Dexter, D.T., Wells, F.R., Lees, A.J., Agid, F., Agid, Y., Jenner, P. and Marsden, C.D. (1989) "Increased nigral iron content and alterations in other metal ions occuring in brain in Parkinson's disease", J. Neurochem. 52, 1830-1836.
    • (1989) J. Neurochem. , vol.52 , pp. 1830-1836
    • Dexter, D.T.1    Wells, F.R.2    Lees, A.J.3    Agid, F.4    Agid, Y.5    Jenner, P.6    Marsden, C.D.7
  • 58
    • 0026704075 scopus 로고
    • "Alterations in levels of iron, ferritin, and other trace metals in neurodegenerative diseases affecting the basal ganglia"
    • Dexter, D.T., Jenner, P., Schapira, A.H.V. and Marsden, C.D. (1992) "Alterations in levels of iron, ferritin, and other trace metals in neurodegenerative diseases affecting the basal ganglia", Ann. Neurol. 32, 94-100.
    • (1992) Ann. Neurol. , vol.32 , pp. 94-100
    • Dexter, D.T.1    Jenner, P.2    Schapira, A.H.V.3    Marsden, C.D.4
  • 59
  • 60
    • 0034677467 scopus 로고    scopus 로고
    • "Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter"
    • Donovan, A., Brownlie, A., Zhou, Y., et al., (2000) "Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter", Nature 403, 776-781.
    • (2000) Nature , vol.403 , pp. 776-781
    • Donovan, A.1    Brownlie, A.2    Zhou, Y.3
  • 63
    • 0032813648 scopus 로고    scopus 로고
    • "Significance of neuromelanin for neurodegeneration in Parkinson's disease"
    • Double, K.L., Riederer, P. and Gerlach, M. (1999) "Significance of neuromelanin for neurodegeneration in Parkinson's disease", Drug News Perspect. 12, 333-340.
    • (1999) Drug News Perspect. , vol.12 , pp. 333-340
    • Double, K.L.1    Riederer, P.2    Gerlach, M.3
  • 66
    • 0034642214 scopus 로고    scopus 로고
    • "Increased levels of plasma malondialdehyde in Friedreich ataxia"
    • Emond, M., Lepage, G., Vanasse, M. and Pandolfo, M. (2000) "Increased levels of plasma malondialdehyde in Friedreich ataxia", Neurology 55, 1752-1753.
    • (2000) Neurology , vol.55 , pp. 1752-1753
    • Emond, M.1    Lepage, G.2    Vanasse, M.3    Pandolfo, M.4
  • 68
    • 0035896709 scopus 로고    scopus 로고
    • "Huntington's disease: A bimolecular vision"
    • Fernandez Leite, J. (2001) "Huntington's disease: a bimolecular vision", Rev. Neurol. 32, 762-767.
    • (2001) Rev. Neurol. , vol.32 , pp. 762-767
    • Fernandez Leite, J.1
  • 69
    • 0032844381 scopus 로고    scopus 로고
    • "Lactoferrin is synthesized by mouse brain tissue and its expression is enhanced after MPTP treatment"
    • Fillebeen, C., Mitchell, V., Dexter, D., Benaissa, M., Beauvillain, J.C., Spik, G. and Pierce, A. (1999) "Lactoferrin is synthesized by mouse brain tissue and its expression is enhanced after MPTP treatment", Mol. Brain. Res. 72, 183-194.
    • (1999) Mol. Brain Res. , vol.72 , pp. 183-194
    • Fillebeen, C.1    Mitchell, V.2    Dexter, D.3    Benaissa, M.4    Beauvillain, J.C.5    Spik, G.6    Pierce, A.7
  • 70
    • 0032800601 scopus 로고    scopus 로고
    • "Low iron concentration and aconitase deficiency in a yeast frataxin homologue deficient strain"
    • Foury, F. (1999) "Low iron concentration and aconitase deficiency in a yeast frataxin homologue deficient strain", FEBS Lett. 456, 281-284.
    • (1999) FEBS Lett. , vol.456 , pp. 281-284
    • Foury, F.1
  • 71
    • 0035896520 scopus 로고    scopus 로고
    • "Mitochondrial control of iron homeostasis: A genome wide analysis of gene expression in a yeast frataxin deficient mutant"
    • Foury, F. and Talibi, D. (2000) "Mitochondrial control of iron homeostasis: a genome wide analysis of gene expression in a yeast frataxin deficient mutant", J. Biol. Chem. 276, 7762-7768.
    • (2000) J. Biol. Chem. , vol.276 , pp. 7762-7768
    • Foury, F.1    Talibi, D.2
  • 72
    • 0032529707 scopus 로고    scopus 로고
    • "Multiple-system atrophy: A new alpha-synuclein disease"
    • Gai, W.P., Power, J.H., Blumbergs, P.C. and Blessing, W.W. (1998) "Multiple-system atrophy: a new alpha-synuclein disease", Lancet 352, 547-648.
    • (1998) Lancet , vol.352 , pp. 547-648
    • Gai, W.P.1    Power, J.H.2    Blumbergs, P.C.3    Blessing, W.W.4
  • 73
    • 0033897735 scopus 로고    scopus 로고
    • "Neurodegeneration with brain iron accumulation, type 1 is characterized by alpha-, beta-, and gamma-synuclein neuropathology"
    • Galvin, J.E., Giasson, B., Hurtig, H.I., Lee, V.M. and Trojanowski, J.Q. (2000) "Neurodegeneration with brain iron accumulation, type 1 is characterized by alpha-, beta-, and gamma-synuclein neuropathology", Am. J. Pathol. 157, 361-368.
    • (2000) Am. J. Pathol. , vol.157 , pp. 361-368
    • Galvin, J.E.1    Giasson, B.2    Hurtig, H.I.3    Lee, V.M.4    Trojanowski, J.Q.5
  • 74
    • 0027753864 scopus 로고
    • "Is acquired idiopathic sideroblastic anemia (AISA) a disorder of mitochondrial DNA?"
    • Gattermann, N., Aul, C. and Schneider, W. (1993) "Is acquired idiopathic sideroblastic anemia (AISA) a disorder of mitochondrial DNA?", Leukemia 7, 2069-2076.
    • (1993) Leukemia , vol.7 , pp. 2069-2076
    • Gattermann, N.1    Aul, C.2    Schneider, W.3
  • 76
    • 0028000825 scopus 로고
    • "Altered brain metabolism of iron as a cause of neurodegenerative diseases"
    • Gerlach, M., Ben-Shachar, D., Riederer, P. and Youdim, M.B. (1994) "Altered brain metabolism of iron as a cause of neurodegenerative diseases", J. Neurochem. 63, 793-807.
    • (1994) J. Neurochem. , vol.63 , pp. 793-807
    • Gerlach, M.1    Ben-Shachar, D.2    Riederer, P.3    Youdim, M.B.4
  • 77
    • 0004181515 scopus 로고    scopus 로고
    • Die Parkinsonkrankheit, Grundlagen, Klinik, Therapie
    • (Springer, Wien, NY)
    • Gerlach, M., Reichmann, H. and Riederer, P. (2001) Die Parkinsonkrankheit, Grundlagen, Klinik, Therapie (Springer, Wien, NY).
    • (2001)
    • Gerlach, M.1    Reichmann, H.2    Riederer, P.3
  • 78
    • 0030921671 scopus 로고    scopus 로고
    • "Hereditary hyperferritinemia-cataract syndrome caused by a 29-base pair deletion in the iron responsive element of ferritin L-subunit gene"
    • Girelli, D., Corrocher, R., Bisceglia, L., Olivieri, O., Zelante, L., Panozzo, G. and Gaspari, P. (1997) "Hereditary hyperferritinemia-cataract syndrome caused by a 29-base pair deletion in the iron responsive element of ferritin L-subunit gene", Blood 90, 2084-2088.
    • (1997) Blood , vol.90 , pp. 2084-2088
    • Girelli, D.1    Corrocher, R.2    Bisceglia, L.3    Olivieri, O.4    Zelante, L.5    Panozzo, G.6    Gaspari, P.7
  • 79
    • 0031816970 scopus 로고    scopus 로고
    • "Aceruloplaminemia"
    • Gitlin, J.D. (1998) "Aceruloplaminemia", Pediatr. Res. 44, 271-276.
    • (1998) Pediatr. Res. , vol.44 , pp. 271-276
    • Gitlin, J.D.1
  • 80
    • 0037013194 scopus 로고    scopus 로고
    • "Magnesium inhibits spontaneous and iron-induced aggregation of alpha-synuclein. Magnesium inhibits spontaneous and iron-induced aggregation of alpha-synuclein"
    • Golts, N., Snyder, H., Frasier, M., Theisler, C., Choi, P. and Wolozin, B. (2002) "Magnesium inhibits spontaneous and iron-induced aggregation of alpha-synuclein. Magnesium inhibits spontaneous and iron-induced aggregation of alpha-synuclein", J. Biol. Chem. 277, 16116-16123.
    • (2002) J. Biol. Chem. , vol.277 , pp. 16116-16123
    • Golts, N.1    Snyder, H.2    Frasier, M.3    Theisler, C.4    Choi, P.5    Wolozin, B.6
  • 81
    • 0033709847 scopus 로고    scopus 로고
    • "Friedreich's ataxia and iron metabolism"
    • Gordon, N. (2000) "Friedreich's ataxia and iron metabolism", Brain Dev. 22, 465-468.
    • (2000) Brain Dev. , vol.22 , pp. 465-468
    • Gordon, N.1
  • 82
    • 0028998624 scopus 로고
    • "Increased iron-related MRI contrast in the substantia nigra in Parkinson's disease"
    • Gorell, J.M., Ordidge, R.J., Brown, G.G., Deniau, J.C., Buderer, N.M. and Helpern, J.A. (1995) "Increased iron-related MRI contrast in the substantia nigra in Parkinson's disease", Neurology 45, 1138-1143.
    • (1995) Neurology , vol.45 , pp. 1138-1143
    • Gorell, J.M.1    Ordidge, R.J.2    Brown, G.G.3    Deniau, J.C.4    Buderer, N.M.5    Helpern, J.A.6
  • 83
    • 0027937548 scopus 로고
    • "Oxidative stress: Free radical production in neural degeneration"
    • Götz, M., Künig, K., Riederer, P. and Youdim, M. (1994) "Oxidative stress: free radical production in neural degeneration", Pharmacol. Ther. 63, 37-122.
    • (1994) Pharmacol. Ther. , vol.63 , pp. 37-122
    • Götz, M.1    Künig, K.2    Riederer, P.3    Youdim, M.4
  • 84
    • 0032898122 scopus 로고    scopus 로고
    • "Iron in the basal ganglia in Parkinson's disease. An in vitro study using extended X-ray absorption find structure and cryoelectron microscopy"
    • Griffiths, P.D., Dobson, B.R., Jones, G.R. and Clarke, D.T. (1999) "Iron in the basal ganglia in Parkinson's disease. An in vitro study using extended X-ray absorption find structure and cryoelectron microscopy", Brain 122, 667-673.
    • (1999) Brain , vol.122 , pp. 667-673
    • Griffiths, P.D.1    Dobson, B.R.2    Jones, G.R.3    Clarke, D.T.4
  • 85
    • 0033103978 scopus 로고    scopus 로고
    • "The iron transport protein NRAMP2 is an integral membrane glycoprotein that colocalizes with transferrin in recycling endosomes"
    • Gruenheid, S., Canonne-Hergaux, F., Gauthier, S., Hackam, D.J., Grinstein, S. and Gros, P. (1999) "The iron transport protein NRAMP2 is an integral membrane glycoprotein that colocalizes with transferrin in recycling endosomes", J. Exp. Med. 189, 831-841.
    • (1999) J. Exp. Med. , vol.189 , pp. 831-841
    • Gruenheid, S.1    Canonne-Hergaux, F.2    Gauthier, S.3    Hackam, D.J.4    Grinstein, S.5    Gros, P.6
  • 87
    • 0030697289 scopus 로고    scopus 로고
    • "Functional expression cloning and characterization of SFT, a stimulator of Fe transport"
    • Gutierrez, J.A., Yu, J., Rivera, S. and Wessling-Resnick, M. (1997) "Functional expression cloning and characterization of SFT, a stimulator of Fe transport", J. Cell Biol. 139, 895-905.
    • (1997) J. Cell Biol. , vol.139 , pp. 895-905
    • Gutierrez, J.A.1    Yu, J.2    Rivera, S.3    Wessling-Resnick, M.4
  • 88
    • 0032583601 scopus 로고    scopus 로고
    • "Characterization and chromosomal mapping of the human gene for SFT, a stimulator of Fe transport"
    • Gutierrez, J.A., Yu, J. and Wessling-Resnick, M. (1998) "Characterization and chromosomal mapping of the human gene for SFT, a stimulator of Fe transport", Biochem. Biophys. Res. Commun. 253, 739-742.
    • (1998) Biochem. Biophys. Res. Commun. , vol.253 , pp. 739-742
    • Gutierrez, J.A.1    Yu, J.2    Wessling-Resnick, M.3
  • 89
    • 0033506728 scopus 로고    scopus 로고
    • "Regulation of genes of iron metabolism by the iron-response proteins"
    • Haile, D.J. (1999) "Regulation of genes of iron metabolism by the iron-response proteins", Am. J. Med. Sci. 318, 230-240.
    • (1999) Am. J. Med. Sci. , vol.318 , pp. 230-240
    • Haile, D.J.1
  • 90
    • 84961042345 scopus 로고
    • "The effect of age on non-haem iron in the human brain"
    • Hallgren, B. and Sourander, P. (1958) "The effect of age on non-haem iron in the human brain", J. Neurochem. 3, 41-51.
    • (1958) J. Neurochem. , vol.3 , pp. 41-51
    • Hallgren, B.1    Sourander, P.2
  • 91
    • 0029434793 scopus 로고
    • "The nosology of Hallervorden-Spatz disease"
    • Halliday, W. (1995) "The nosology of Hallervorden-Spatz disease", J. Neurol. Sci. 134, 84-91.
    • (1995) J. Neurol. Sci. , vol.134 , pp. 84-91
    • Halliday, W.1
  • 92
    • 0034796353 scopus 로고    scopus 로고
    • "Role of free radicals in the neurodegenerative diseases: Therapeutic implications for antioxidant treatment"
    • Halliwell, B. (2001) "Role of free radicals in the neurodegenerative diseases: therapeutic implications for antioxidant treatment", Drugs Aging 18, 685-716.
    • (2001) Drugs Aging , vol.18 , pp. 685-716
    • Halliwell, B.1
  • 93
    • 0019782799 scopus 로고
    • "Friedreich's ataxia: A clinical a genetic study of 90 families with an analysis of early diagnostic criteria and intrafamilial clustering of clinical features"
    • Harding, A.E. (1981) "Friedreich's ataxia: a clinical a genetic study of 90 families with an analysis of early diagnostic criteria and intrafamilial clustering of clinical features", Brain 104, 598-620.
    • (1981) Brain , vol.104 , pp. 598-620
    • Harding, A.E.1
  • 95
    • 0032875387 scopus 로고    scopus 로고
    • "Targeted gene disruption reveals an essential role for ceruloplasmin in cellular iron efflux"
    • Harris, Z.L., Durley, A.P., Man, T.K. and Giltin, J.D. (1999) "Targeted gene disruption reveals an essential role for ceruloplasmin in cellular iron efflux", Proc. Natl Acad. Sci. USA 96, 10812-10817.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 10812-10817
    • Harris, Z.L.1    Durley, A.P.2    Man, T.K.3    Giltin, J.D.4
  • 96
    • 0030608152 scopus 로고    scopus 로고
    • "The ferritin: Molecular properties, iron storage function and cellular regulation"
    • Harrison, P.M. and Arrosio, P. (1996) "The ferritin: molecular properties, iron storage function and cellular regulation", Biochim. Biophys. Acta 1275, 161-203.
    • (1996) Biochim. Biophys. Acta , vol.1275 , pp. 161-203
    • Harrison, P.M.1    Arrosio, P.2
  • 97
    • 0032551656 scopus 로고    scopus 로고
    • "Human recombinant NACP/alphasynuclein is aggregated and fibrillated in vitro: Relevance for Lewy body disease"
    • Hashimoto, M., Hsu, L.J., Sisk, A., Xia, Y., Takeda, A., Sundsmo, M. and Masliah, E. (1998) "Human recombinant NACP/alphasynuclein is aggregated and fibrillated in vitro: relevance for Lewy body disease", Brain Res. 799, 301-306.
    • (1998) Brain Res. , vol.799 , pp. 301-306
    • Hashimoto, M.1    Hsu, L.J.2    Sisk, A.3    Xia, Y.4    Takeda, A.5    Sundsmo, M.6    Masliah, E.7
  • 98
    • 0033577159 scopus 로고    scopus 로고
    • "Oxidative stress induces amyloid-like aggregate formation of NACP/α-synuclein in vitro"
    • Hashimoto, M., Hsu, L.J., Xia, Y., Takeda, A., Sisk, A. and Masliah, E. (1999) "Oxidative stress induces amyloid-like aggregate formation of NACP/α-synuclein in vitro", NeuroReport 10, 717-721.
    • (1999) NeuroReport , vol.10 , pp. 717-721
    • Hashimoto, M.1    Hsu, L.J.2    Xia, Y.3    Takeda, A.4    Sisk, A.5    Masliah, E.6
  • 100
    • 0037059741 scopus 로고    scopus 로고
    • "Biochemical analysis of a missense mutation in aceruloplasminemia"
    • Hellmann, N.E., Kono, S., Miyajima, H. and Gitlin, J.D. (2002) "Biochemical analysis of a missense mutation in aceruloplasminemia", J. Biol. Chem. 277, 1375-1380.
    • (2002) J. Biol. Chem. , vol.277 , pp. 1375-1380
    • Hellmann, N.E.1    Kono, S.2    Miyajima, H.3    Gitlin, J.D.4
  • 101
    • 0029758487 scopus 로고    scopus 로고
    • "Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress"
    • Hentze, M.W. and Kuhn, L.C. (1996) "Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress", Proc. Natl Acad. Sci. USA 93, 8175-8182.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 8175-8182
    • Hentze, M.W.1    Kuhn, L.C.2
  • 103
    • 0026621245 scopus 로고
    • "ABC transporters: From microorganisms to man"
    • Higgins, C.F. (1992) "ABC transporters: from microorganisms to man", Annu. Rev. Cell. Biol. 8, 67-113.
    • (1992) Annu. Rev. Cell. Biol. , vol.8 , pp. 67-113
    • Higgins, C.F.1
  • 105
    • 0027480960 scopus 로고
    • "A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes"
    • Huntington's Disease Collaborative Research Group
    • Huntington's Disease Collaborative Research Group(1993) "A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes", Cell 72, 971-983.
    • (1993) Cell , vol.72 , pp. 971-983
  • 106
    • 0029434395 scopus 로고
    • "Low intensity areas observed on T2-weighted magnetic resonance imaging of the cerebral cortex in various neurological disorders"
    • Imon, Y., Yamaguchi, S., Yamamura, Y., Tsuji, S., Kajima, T., Ito, K. and Nakamura, S. (1995) "Low intensity areas observed on T2-weighted magnetic resonance imaging of the cerebral cortex in various neurological disorders", J. Neurol. Sci. 134 (Suppl.), 27-32.
    • (1995) J. Neurol. Sci. , vol.134 , Issue.SUPPL. , pp. 27-32
    • Imon, Y.1    Yamaguchi, S.2    Yamamura, Y.3    Tsuji, S.4    Kajima, T.5    Ito, K.6    Nakamura, S.7
  • 107
    • 0029935613 scopus 로고    scopus 로고
    • "Reactive microglia specifically associated with amyloid plaques in Alzheimer's disease brain tissue express melanotransferrin"
    • Jefferies, W.A., Food, M.R., Gabathuler, R., Rothenberger, S., Yamada, T., Yasuhara, O. and McGeer, P.L. (1996) "Reactive microglia specifically associated with amyloid plaques in Alzheimer's disease brain tissue express melanotransferrin", Brain Res. 712, 122-126.
    • (1996) Brain Res. , vol.712 , pp. 122-126
    • Jefferies, W.A.1    Food, M.R.2    Gabathuler, R.3    Rothenberger, S.4    Yamada, T.5    Yasuhara, O.6    McGeer, P.L.7
  • 108
    • 0019244756 scopus 로고
    • "Progressive supranuclear palys: Clinicopathological and biochemical studies"
    • Jellinger, K., Riederer, P. and Tomonaga, M. (1980) "Progressive supranuclear palys: clinicopathological and biochemical studies", J. Neural Transm. Suppl. 16, 111-128.
    • (1980) J. Neural Transm. Suppl. , vol.16 , pp. 111-128
    • Jellinger, K.1    Riederer, P.2    Tomonaga, M.3
  • 110
    • 0032975570 scopus 로고    scopus 로고
    • "The role of iron in neurodegeneration"
    • Jellinger, K.A. (1999) "The role of iron in neurodegeneration", Drugs Aging 14, 115-140.
    • (1999) Drugs Aging , vol.14 , pp. 115-140
    • Jellinger, K.A.1
  • 111
    • 0011709095 scopus 로고    scopus 로고
    • "The Huntington's disease gene and its protein product"
    • Harper, P.S., ed, 2nd Ed. (W.B. Saunders Co., Philadelphia)
    • Jones, A.L. (1996) "The Huntington's disease gene and its protein product", In: Harper, P.S., ed, Huntington's Disease, 2nd Ed. (W.B. Saunders Co., Philadelphia), pp. 293-316.
    • (1996) Huntington's Disease , pp. 293-316
    • Jones, A.L.1
  • 112
    • 0037093531 scopus 로고    scopus 로고
    • "The mitochondrial protein frataxin prevents nuclear damage"
    • Karthikeyan, G., Lewis, L.K. and Resnick, M.A. (2002) "The mitochondrial protein frataxin prevents nuclear damage", Hum. Mol. Genet. 16, 1351-1362.
    • (2002) Hum. Mol. Genet. , vol.16 , pp. 1351-1362
    • Karthikeyan, G.1    Lewis, L.K.2    Resnick, M.A.3
  • 113
    • 0029017315 scopus 로고
    • "Aluminium, calcium, and iron in the spinal cord of patients with sporadic amyotrophic lateral sclerosis using laser microprobe mass spectroscopy: A preliminary study"
    • Kasarski, E.J., Tandon, L., Lovell, M.A. and Ehmann, W.D. (1995) "Aluminium, calcium, and iron in the spinal cord of patients with sporadic amyotrophic lateral sclerosis using laser microprobe mass spectroscopy: a preliminary study", J. Neurol. Sci. 130, 203-208.
    • (1995) J. Neurol. Sci. , vol.130 , pp. 203-208
    • Kasarski, E.J.1    Tandon, L.2    Lovell, M.A.3    Ehmann, W.D.4
  • 114
    • 0025999502 scopus 로고
    • "Argyrophilic ubiquitinated cytoplasmic inclusions of Leu-7-positive glial cells in olivopontocerebellar atrophy (multiple system atrophy)"
    • Kato, S., Nakamura, H., Hirano, A., Ito, H., Llena, J.F. and Yen, S.H. (1991) "Argyrophilic ubiquitinated cytoplasmic inclusions of Leu-7-positive glial cells in olivopontocerebellar atrophy (multiple system atrophy)", Acta Neuropathol. (Berl.) 82, 488-493.
    • (1991) Acta Neuropathol. (Berl.) , vol.82 , pp. 488-493
    • Kato, S.1    Nakamura, H.2    Hirano, A.3    Ito, H.4    Llena, J.F.5    Yen, S.H.6
  • 116
    • 0029955035 scopus 로고    scopus 로고
    • "Serum levels of the iron binding protein p97 are elevated in Alzheimer's disease"
    • Kennard, M.L., Feldman, H., Yamada, T. and Jefferies, W.A. (1996) "Serum levels of the iron binding protein p97 are elevated in Alzheimer's disease", Nat. Med. 2, 1230-1235.
    • (1996) Nat. Med. , vol.2 , pp. 1230-1235
    • Kennard, M.L.1    Feldman, H.2    Yamada, T.3    Jefferies, W.A.4
  • 118
    • 0030608677 scopus 로고    scopus 로고
    • "The ABC transporter Atm1p is required for mitochondrial iron homeostasis"
    • Kispal, G., Csere, P., Guiard, B. and Lill, R. (1997) "The ABC transporter Atm1p is required for mitochondrial iron homeostasis", FEBS Lett. 418, 346-350.
    • (1997) FEBS Lett. , vol.418 , pp. 346-350
    • Kispal, G.1    Csere, P.2    Guiard, B.3    Lill, R.4
  • 119
    • 0033565665 scopus 로고    scopus 로고
    • "The mitochondrial proteins Atm1p and Nfs1p are essential for biogenesis of cytosolic Fe/S proteins"
    • Kispal, G., Csere, P., Prohl, C. and Lill, R. (1999) "The mitochondrial proteins Atm1p and Nfs1p are essential for biogenesis of cytosolic Fe/S proteins", EMBO J. 18, 3981-3989.
    • (1999) EMBO J. , vol.18 , pp. 3981-3989
    • Kispal, G.1    Csere, P.2    Prohl, C.3    Lill, R.4
  • 120
    • 0029800745 scopus 로고    scopus 로고
    • "Expression of the ceruloplasmin gene in the human retina and brain: Implications for a pathogenetic model in aceruloplasminea"
    • Klomb, L.W. and Gitlin, J.D. (1996) "Expression of the ceruloplasmin gene in the human retina and brain: implications for a pathogenetic model in aceruloplasminea", Hum. Mol. Gen. 5, 1989-1996.
    • (1996) Hum. Mol. Gen. , vol.5 , pp. 1989-1996
    • Klomb, L.W.1    Gitlin, J.D.2
  • 121
    • 0035021038 scopus 로고    scopus 로고
    • "Expression of stimulator of Fe transport is not enhanced in Hfe knockout mice"
    • Knutson, M.D., Levy, J.E., Andrews, N.C. and Wessling-Resnick, M. (2001) "Expression of stimulator of Fe transport is not enhanced in Hfe knockout mice", J. Nutr. 131, 1459-1464.
    • (2001) J. Nutr. , vol.131 , pp. 1459-1464
    • Knutson, M.D.1    Levy, J.E.2    Andrews, N.C.3    Wessling-Resnick, M.4
  • 122
    • 0034845760 scopus 로고    scopus 로고
    • "Iron in Hallervorden-Spatz syndrome"
    • Koeppen, A.H. and Dickson, A.C. (2001) "Iron in Hallervorden-Spatz syndrome", Pediatr. Neurol. 25, 148-155.
    • (2001) Pediatr. Neurol. , vol.25 , pp. 148-155
    • Koeppen, A.H.1    Dickson, A.C.2
  • 123
    • 0034081056 scopus 로고    scopus 로고
    • "Aceruloplasminemia with a novel mutation associated with parkinsonism"
    • Kohno, S., Miyajima, H. and Takahashi, Y. (1999) "Aceruloplasminemia with a novel mutation associated with parkinsonism", Neurogenetics 2, 237-238.
    • (1999) Neurogenetics , vol.2 , pp. 237-238
    • Kohno, S.1    Miyajima, H.2    Takahashi, Y.3
  • 124
    • 0034672736 scopus 로고    scopus 로고
    • "Defective electron transfer in complex I and IV in patients with aceruloplasminemia"
    • Kohno, S., Miyajima, H., Takahashi, Y., Suzuki, H. and Hishida, A. (2000) "Defective electron transfer in complex I and IV in patients with aceruloplasminemia", J. Neurol. Sci. 182, 57-60.
    • (2000) J. Neurol. Sci. , vol.182 , pp. 57-60
    • Kohno, S.1    Miyajima, H.2    Takahashi, Y.3    Suzuki, H.4    Hishida, A.5
  • 125
    • 0031990490 scopus 로고    scopus 로고
    • "Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease. Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease"
    • Kruger, R., Kuhn, W., Muller, T., Woitalla, D., Graeber, M., Kosel, S., Przuntek, H., Epplen, J.T., Schols, L. and Riess, O. (1998) "Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease. Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease", Nat. Genet. 18, 106-108.
    • (1998) Nat. Genet. , vol.18 , pp. 106-108
    • Kruger, R.1    Kuhn, W.2    Muller, T.3    Woitalla, D.4    Graeber, M.5    Kosel, S.6    Przuntek, H.7    Epplen, J.T.8    Schols, L.9    Riess, O.10
  • 126
    • 0019169563 scopus 로고
    • "The cardiomyopathy of Friedreich's ataxia morphological observations in 3 cases"
    • Lamarche, J.B., Cote, M. and Lemieux, B. (1980) "The cardiomyopathy of Friedreich's ataxia morphological observations in 3 cases", Can. J. Neurol. Sci. 7, 389-396.
    • (1980) Can. J. Neurol. Sci. , vol.7 , pp. 389-396
    • Lamarche, J.B.1    Cote, M.2    Lemieux, B.3
  • 127
    • 0023112148 scopus 로고
    • "Saccades in Huntingon's disease: Initiation defects and distractability"
    • Lasker, A.G., Zee, D.S., Hain, T.C., Folstein, S.E. and Singer, H.S. (1987) "Saccades in Huntingon's disease: initiation defects and distractability", Neurology 37, 364.
    • (1987) Neurology , vol.37 , pp. 364
    • Lasker, A.G.1    Zee, D.S.2    Hain, T.C.3    Folstein, S.E.4    Singer, H.S.5
  • 128
    • 0028321575 scopus 로고
    • "The iron-binding protein lactotransferrin is present in pathologic lesions in a variety of neurodegenerative disorders: A comparative immunohistochemical analysis"
    • Leveugle, B., Spik, G., Perl, D.P, Bouras, C., Fillit, H.M. and Hof, P.R. (1994) "The iron-binding protein lactotransferrin is present in pathologic lesions in a variety of neurodegenerative disorders: a comparative immunohistochemical analysis", Brain Res. 650, 20-31.
    • (1994) Brain Res. , vol.650 , pp. 20-31
    • Leveugle, B.1    Spik, G.2    Perl, D.P.3    Bouras, C.4    Fillit, H.M.5    Hof, P.R.6
  • 129
    • 0029997918 scopus 로고    scopus 로고
    • "Cellular distribution of the iron-binding protein lactotransferrin in the mesencephalon of Parkinson's disease"
    • Leveugle, B., Faucheux, B.A., Bouras, C., Nillesse, N., Spik, G., Hirsch, E.C., Agid, Y. and Hof, P.R. (1996) "Cellular distribution of the iron-binding protein lactotransferrin in the mesencephalon of Parkinson's disease", Acta Neuropathol. 91, 566-572.
    • (1996) Acta Neuropathol. , vol.91 , pp. 566-572
    • Leveugle, B.1    Faucheux, B.A.2    Bouras, C.3    Nillesse, N.4    Spik, G.5    Hirsch, E.C.6    Agid, Y.7    Hof, P.R.8
  • 130
    • 0030788672 scopus 로고    scopus 로고
    • "Iron deposits in multiple sclerosis and Alzheimer's disease brains"
    • LeVine, S.M. (1997) "Iron deposits in multiple sclerosis and Alzheimer's disease brains", Brain Res. 760, 298-303.
    • (1997) Brain Res. , vol.760 , pp. 298-303
    • LeVine, S.M.1
  • 131
    • 0032959574 scopus 로고    scopus 로고
    • "Transferrin receptor is necessary for development of erythorcytes and the nervous system"
    • Levy, J.E., Jin, O., Fujiwara, Y., Kuo, F. and Andrews, N.C. (1999) "Transferrin receptor is necessary for development of erythorcytes and the nervous system", Nat. Genet. 21, 396-399.
    • (1999) Nat. Genet. , vol.21 , pp. 396-399
    • Levy, J.E.1    Jin, O.2    Fujiwara, Y.3    Kuo, F.4    Andrews, N.C.5
  • 133
    • 0035025935 scopus 로고    scopus 로고
    • "Mitochondrial dysfunction in Friedreich's ataxia"
    • Lodi, R., Taylor, D.J. and Schapira, A.H.V (2001b) "Mitochondrial dysfunction in Friedreich's ataxia", Biol. Signals Recept. 10, 263-270.
    • (2001) Biol. Signals Recept. , vol.10 , pp. 263-270
    • Lodi, R.1    Taylor, D.J.2    Schapira, A.H.V.3
  • 135
    • 0034896516 scopus 로고    scopus 로고
    • "Ceruloplasmin immunoreactivity in neurodegenerative disorders"
    • Loeffler, D.A., Sima, A.A. and LeWitt, P.A. (2001) "Ceruloplasmin immunoreactivity in neurodegenerative disorders", Free Radic. Res. 35, 111-118.
    • (2001) Free Radic. Res. , vol.35 , pp. 111-118
    • Loeffler, D.A.1    Sima, A.A.2    LeWitt, P.A.3
  • 138
    • 0035970292 scopus 로고    scopus 로고
    • "The mitochondrial proteins Ssq1 and Jac1 are required for the assembly of iron sulfur clusters in mitochondria"
    • Lutz, T., Westermann, B., Neupert, W. and Herrmann, J.M. (2001) "The mitochondrial proteins Ssq1 and Jac1 are required for the assembly of iron sulfur clusters in mitochondria", J. Mol. Biol. 307, 815-825.
    • (2001) J. Mol. Biol. , vol.307 , pp. 815-825
    • Lutz, T.1    Westermann, B.2    Neupert, W.3    Herrmann, J.M.4
  • 139
    • 0036098482 scopus 로고    scopus 로고
    • "Friedreich ataxia: Effects of genetic understanding on clinical evaluation and therapy"
    • Lynch, D.R., Farmer, J.M., Balcer, L.J. and Wilson, R.B. (2002) "Friedreich ataxia: effects of genetic understanding on clinical evaluation and therapy", Arch. Neurol. 59, 743-747.
    • (2002) Arch. Neurol. , vol.59 , pp. 743-747
    • Lynch, D.R.1    Farmer, J.M.2    Balcer, L.J.3    Wilson, R.B.4
  • 140
    • 0033134765 scopus 로고    scopus 로고
    • "Existing and emerging mechanisms for transport of iron and manganese to the brain"
    • Malecki, E.A., Devenyi, A.G., Beard, J.L. and Connor, J.R. (1999) "Existing and emerging mechanisms for transport of iron and manganese to the brain", J. Neurosci. Res. 56, 113-122.
    • (1999) J. Neurosci. Res. , vol.56 , pp. 113-122
    • Malecki, E.A.1    Devenyi, A.G.2    Beard, J.L.3    Connor, J.R.4
  • 141
    • 0034517802 scopus 로고    scopus 로고
    • "cDNA microarray to study gene expression of dopaminergic neurodegeneration and neuroprotection in MPTP and 6-hydroxydopamine models: Implications for idiopathic Parkinson's disease"
    • Mandel, S., Grunblatt, E. and Youdim, M. (2000) "cDNA microarray to study gene expression of dopaminergic neurodegeneration and neuroprotection in MPTP and 6-hydroxydopamine models: implications for idiopathic Parkinson's disease", J. Neural Transm. Suppl. 60, 117-124.
    • (2000) J. Neural Transm. Suppl. , vol.60 , pp. 117-124
    • Mandel, S.1    Grunblatt, E.2    Youdim, M.3
  • 142
    • 0022876328 scopus 로고
    • "Huntington's diease: Pathogenesis and management"
    • Martin, J.B. and Gusella, J.F. (1986) "Huntington's diease: pathogenesis and management", N. Engl. J. Med. 315, 1267-1276.
    • (1986) N. Engl. J. Med. , vol.315 , pp. 1267-1276
    • Martin, J.B.1    Gusella, J.F.2
  • 143
    • 0031975341 scopus 로고    scopus 로고
    • "A point mutation in the bulge of the iron-responsive element of the L ferritin gene in two families with the hereditary hyperferritinemia-cataract syndrome"
    • Martin, M.E., Fargion, S., Brissot, P., Pellat, B. and Beaumont, C. (1998a) "A point mutation in the bulge of the iron-responsive element of the L ferritin gene in two families with the hereditary hyperferritinemia-cataract syndrome", Blood 91, 319-323.
    • (1998) Blood , vol.91 , pp. 319-323
    • Martin, M.E.1    Fargion, S.2    Brissot, P.3    Pellat, B.4    Beaumont, C.5
  • 144
    • 0031918718 scopus 로고    scopus 로고
    • "Increased basal ganglia iron in striatonigral degeneration: In vivo estimation with magnetic resonance"
    • Martin, W.R., Roberts, T.E., Ye, F.Q. and Allen, P.S. (1998) "Increased basal ganglia iron in striatonigral degeneration: in vivo estimation with magnetic resonance", Can. J. Neurol. Sci. 25, 44-47.
    • (1998) Can. J. Neurol. Sci. , vol.25 , pp. 44-47
    • Martin, W.R.1    Roberts, T.E.2    Ye, F.Q.3    Allen, P.S.4
  • 146
    • 0025063609 scopus 로고
    • "Excitatory amino acid neurotoxicity and neurodegenerative disease"
    • A TiPS special report
    • Medrum, B. and Garthwaite, J. (1990) "Excitatory amino acid neurotoxicity and neurodegenerative disease", Trends Pharmacol. Sci., 54-62, A TiPS special report.
    • (1990) Trends Pharmacol. Sci. , pp. 54-62
    • Medrum, B.1    Garthwaite, J.2
  • 147
    • 0033546624 scopus 로고    scopus 로고
    • "Estimation of the gene frequency of aceruloplasminemia in Japan"
    • Miyajima, H., Kohno, S., Takahashi, Y., Yonekawa, O. and Kanno, T. (1999) "Estimation of the gene frequency of aceruloplasminemia in Japan", Neurology 53, 617-619.
    • (1999) Neurology , vol.53 , pp. 617-619
    • Miyajima, H.1    Kohno, S.2    Takahashi, Y.3    Yonekawa, O.4    Kanno, T.5
  • 148
    • 0035956555 scopus 로고    scopus 로고
    • "Cerebellar ataxia associated with heteroallelic ceruloplasmin gene mutation"
    • Miyajima, H., Kohno, S., Takahashi, Y., Sugimoto, M., Sakamoto, M. and Skai, N. (2001) "Cerebellar ataxia associated with heteroallelic ceruloplasmin gene mutation", Neurology 26, 2205-2210.
    • (2001) Neurology , vol.26 , pp. 2205-2210
    • Miyajima, H.1    Kohno, S.2    Takahashi, Y.3    Sugimoto, M.4    Sakamoto, M.5    Skai, N.6
  • 150
    • 0032533743 scopus 로고    scopus 로고
    • "Evidence for low molecular weight, non-transferrin-bound iron in rat brain and cerebrospinal fluid"
    • Moos, T. and Morgan, E.H. (1998) "Evidence for low molecular weight, non-transferrin-bound iron in rat brain and cerebrospinal fluid", J. Neurosci. Res. 54, 468-494.
    • (1998) J. Neurosci. Res. , vol.54 , pp. 468-494
    • Moos, T.1    Morgan, E.H.2
  • 151
    • 0033961913 scopus 로고    scopus 로고
    • "Transferrin and transferrin receptor function in brain barrier systems"
    • Moos, T. and Morgan, E.H. (2000) "Transferrin and transferrin receptor function in brain barrier systems", Cell Mol. Neurobiol. 20, 77-95.
    • (2000) Cell Mol. Neurobiol. , vol.20 , pp. 77-95
    • Moos, T.1    Morgan, E.H.2
  • 152
    • 0029007765 scopus 로고
    • "Hereditary ceruloplasmin deficiency with hemosiderosis: A clinico-pathological study of a Japanese familiy"
    • Morita, H., Ikeda, S., Yamamoto, K., Morita, S., Yoshida, K., Nomoto, S., Kato, M. and Yanagisawa, N. (1995) "Hereditary ceruloplasmin deficiency with hemosiderosis: a clinico-pathological study of a Japanese familiy", Ann. Neurol. 37, 646-656.
    • (1995) Ann. Neurol. , vol.37 , pp. 646-656
    • Morita, H.1    Ikeda, S.2    Yamamoto, K.3    Morita, S.4    Yoshida, K.5    Nomoto, S.6    Kato, M.7    Yanagisawa, N.8
  • 153
    • 0041893905 scopus 로고    scopus 로고
    • "Biogenesis of iron-sulfur proteins in eukaryotes: A novel task of mitochondria that is inherited from bacteria"
    • Muhlenhoff, U. and Lill, R. (2000) "Biogenesis of iron-sulfur proteins in eukaryotes: a novel task of mitochondria that is inherited from bacteria", Biochim. Biophys. Acta 1459, 370-382.
    • (2000) Biochim. Biophys. Acta , vol.1459 , pp. 370-382
    • Muhlenhoff, U.1    Lill, R.2
  • 154
    • 0032579397 scopus 로고    scopus 로고
    • "Role of ceruloplasmin in cellular iron uptake"
    • Mukhopadhyay, C.K., Attieh, Z.K. and Fox, P.L. (1998) "Role of ceruloplasmin in cellular iron uptake", Science 279, 714-717.
    • (1998) Science , vol.279 , pp. 714-717
    • Mukhopadhyay, C.K.1    Attieh, Z.K.2    Fox, P.L.3
  • 155
    • 0033817296 scopus 로고    scopus 로고
    • "2α-Synuclein accumulation in a case of neurodegeneration with brain iron accumulation type 1 (NBlA-1, formerly Hallervorden-Spatz syndrome). with widespread cortical and brainstem-type Lewy bodies"
    • Neumann, M., Adler, S., Schlüter, O., Kremmer, E., Benecke, R. and Kretzschmar, H.A. (2000) "2α-Synuclein accumulation in a case of neurodegeneration with brain iron accumulation type 1 (NBlA-1, formerly Hallervorden-Spatz syndrome). with widespread cortical and brainstem-type Lewy bodies", Acta Neuropathol. 100, 568-574.
    • (2000) Acta Neuropathol. , vol.100 , pp. 568-574
    • Neumann, M.1    Adler, S.2    Schlüter, O.3    Kremmer, E.4    Benecke, R.5    Kretzschmar, H.A.6
  • 156
    • 0029086742 scopus 로고
    • "Heredita haemochromatosis: A case of iron accumulation in the basal ganglia associated with a parkinsonian syndrome"
    • Nielsen, J.E., Neerup Jensen, L. and Krabbe, B. (1995) "Heredita haemochromatosis: a case of iron accumulation in the basal ganglia associated with a parkinsonian syndrome", J. Neurol. Neurosurg. Psychiatry 59, 318-578.
    • (1995) J. Neurol. Neurosurg. Psychiatry , vol.59 , pp. 318-578
    • Nielsen, J.E.1    Neerup Jensen, L.2    Krabbe, B.3
  • 158
    • 0037076952 scopus 로고    scopus 로고
    • "Role of hydroxyl radical formation in neurotoxicity as revealed by in vivo free radical trapping"
    • Obata, T. (2002) "Role of hydroxyl radical formation in neurotoxicity as revealed by in vivo free radical trapping", Toxicol. Lett. 132, 83-93.
    • (2002) Toxicol. Lett. , vol.132 , pp. 83-93
    • Obata, T.1
  • 161
    • 0026583811 scopus 로고
    • "Magnetic resonance imaging in parkinsonism"
    • Olanow, C.W. (1992) "Magnetic resonance imaging in parkinsonism", Neurol. Clin. 10, 405-420.
    • (1992) Neurol. Clin. , vol.10 , pp. 405-420
    • Olanow, C.W.1
  • 162
    • 0015175326 scopus 로고
    • "Cytotoxic effect of acidic and sulfur containing amino acids on the infant mouse central nervous system"
    • Olney, J.W., Ho, O.L. and Rhee, V. (1971) "Cytotoxic effect of acidic and sulfur containing amino acids on the infant mouse central nervous system", Exp. Brain Res. 14, 61-76.
    • (1971) Exp. Brain Res. , vol.14 , pp. 61-76
    • Olney, J.W.1    Ho, O.L.2    Rhee, V.3
  • 163
    • 0035194691 scopus 로고    scopus 로고
    • "Disease mechanisms revealed by transcription profiling in SOD1-G93A transgenic mouse spinal cord"
    • Olsen, M.K., Roberds, S.L., Ellerbrock, B.R., Fleck, T.J., McKinley, D.K. and Gurney, M.E. (2001) "Disease mechanisms revealed by transcription profiling in SOD1-G93A transgenic mouse spinal cord", Ann. Neurol. 50, 730-740.
    • (2001) Ann. Neurol. , vol.50 , pp. 730-740
    • Olsen, M.K.1    Roberds, S.L.2    Ellerbrock, B.R.3    Fleck, T.J.4    McKinley, D.K.5    Gurney, M.E.6
  • 164
    • 0014027719 scopus 로고
    • "The possible role of the ferrous oxidase activity of ceruloplasmin in normal human serum"
    • Oskai, S., Johnson, D.A. and Frieden, E. (1966) "The possible role of the ferrous oxidase activity of ceruloplasmin in normal human serum", J. Biol. Chem. 241, 11490-11491.
    • (1966) J. Biol. Chem. , vol.241 , pp. 11490-11491
    • Oskai, S.1    Johnson, D.A.2    Frieden, E.3
  • 166
    • 0034663039 scopus 로고    scopus 로고
    • "The A53T α-synuclein mutation increases iron dependent aggregation and toxicity"
    • Osterova-Golts, N., Petrucelli, L., Hardy, J., Lee, J.M., Farer, M. and Wolozin, B. (2000) "The A53T α-synuclein mutation increases iron dependent aggregation and toxicity", J. Neurosci. 20, 6048-6054.
    • (2000) J. Neurosci. , vol.20 , pp. 6048-6054
    • Osterova-Golts, N.1    Petrucelli, L.2    Hardy, J.3    Lee, J.M.4    Farer, M.5    Wolozin, B.6
  • 167
    • 0021926630 scopus 로고
    • "Hereditary sideroblastic anaemia and ataxia: An X-linked recessive disorder"
    • Pagon, R.A., Bird, T.D., Detter, J.C. and Pierce, I. (1985) "Hereditary sideroblastic anaemia and ataxia: an X-linked recessive disorder", J. Med. Genet. 22, 267-273.
    • (1985) J. Med. Genet. , vol.22 , pp. 267-273
    • Pagon, R.A.1    Bird, T.D.2    Detter, J.C.3    Pierce, I.4
  • 168
    • 0033564726 scopus 로고    scopus 로고
    • "Copper(II)-induced self oligomerization of α-synuclein"
    • Paik, S., Shin, H., Lee, J., Chang, C. and Kim, J. (1999) "Copper(II)-induced self oligomerization of α-synuclein", Biochem. J. 340, 821-828.
    • (1999) Biochem. J. , vol.340 , pp. 821-828
    • Paik, S.1    Shin, H.2    Lee, J.3    Chang, C.4    Kim, J.5
  • 169
    • 0035576822 scopus 로고    scopus 로고
    • "Mitochondrial impairment in the cerebellum of the patients with progressive supranuclear palsy"
    • Park, L.C., Albers, D.S., Xu, H., Lindsay, J.G., Beal, M.F. and Gibson, G.E. (2001) "Mitochondrial impairment in the cerebellum of the patients with progressive supranuclear palsy", J. Neurosci. Res. 66, 1028-1034.
    • (2001) J. Neurosci. Res. , vol.66 , pp. 1028-1034
    • Park, L.C.1    Albers, D.S.2    Xu, H.3    Lindsay, J.G.4    Beal, M.F.5    Gibson, G.E.6
  • 170
    • 0034969491 scopus 로고    scopus 로고
    • "Freidreich ataxia: From GAA triplet-repeat expansion to frataxin deficiency"
    • Patel, I.P. and Isaya, G. (2001) "Freidreich ataxia: from GAA triplet-repeat expansion to frataxin deficiency", Am. J. Hum. Genet. 69, 15-24.
    • (2001) Am. J. Hum. Genet. , vol.69 , pp. 15-24
    • Patel, I.P.1    Isaya, G.2
  • 171
    • 0034635402 scopus 로고    scopus 로고
    • "Alternative RNA splicing generates a glycosylphosphtidylinositol-anchored form of ceruloplasmin in mammalian brain"
    • Patel, B.N., Dunn, R.J. and David, S. (2000) "Alternative RNA splicing generates a glycosylphosphtidylinositol-anchored form of ceruloplasmin in mammalian brain", J. Biol. Chem. 275, 4305-4310.
    • (2000) J. Biol. Chem. , vol.275 , pp. 4305-4310
    • Patel, B.N.1    Dunn, R.J.2    David, S.3
  • 172
    • 0003921607 scopus 로고
    • The Human Nervous System
    • ed (Academic Press, San Diego, CA)
    • Paxinos, G., ed, (1990) The Human Nervous System (Academic Press, San Diego, CA).
    • (1990)
    • Paxinos, G.1
  • 173
    • 0343336439 scopus 로고    scopus 로고
    • "Ferritin is associated with the aberrant tau filaments in preogressive supranuclear palsy"
    • Perez, M., Valpuesta, J.M., Montejo de Garcini, E. and Avila, J. (1998) "Ferritin is associated with the aberrant tau filaments in preogressive supranuclear palsy", Am. J. Pathol. 152, 1531-1539.
    • (1998) Am. J. Pathol. , vol.152 , pp. 1531-1539
    • Perez, M.1    Valpuesta, J.M.2    Montejo de Garcini, E.3    Avila, J.4
  • 174
    • 0022381482 scopus 로고
    • "Hallervorden-Spatz disease: Cystein accumulation and cystein dioxygenase deficiency in the globus pallidus"
    • Perry, T.L., Norman, M.G., Yong, V.W, Whiting, S., Crichton, J.U., Hansen, S. and Kish, S.J. (1985) "Hallervorden-Spatz disease: cystein accumulation and cystein dioxygenase deficiency in the globus pallidus", Ann. Neurol. 18, 482-489.
    • (1985) Ann. Neurol. , vol.18 , pp. 482-489
    • Perry, T.L.1    Norman, M.G.2    Yong, V.W.3    Whiting, S.4    Crichton, J.U.5    Hansen, S.6    Kish, S.J.7
  • 177
    • 0032964289 scopus 로고    scopus 로고
    • "Cellular iron metabolism"
    • Ponka, P. (1999) "Cellular iron metabolism", Kidney Int. 55 (Suppl. 69), 2-11.
    • (1999) Kidney Int. , vol.55 , Issue.SUPPL. 69 , pp. 2-11
    • Ponka, P.1
  • 179
    • 0015978141 scopus 로고
    • "Neurofibrillary tangles in progressive supranuclear palsy: Electron microscopic observations"
    • Powell, H.C., London, G.W. and Lampert, P.W. (1974) "Neurofibrillary tangles in progressive supranuclear palsy: electron microscopic observations", J. Neuropathol. Exp. Neurol. 33, 98-106.
    • (1974) J. Neuropathol. Exp. Neurol. , vol.33 , pp. 98-106
    • Powell, H.C.1    London, G.W.2    Lampert, P.W.3
  • 180
    • 0034984521 scopus 로고    scopus 로고
    • "Rethinking the role of ceruloplasmin in brain iron metabolism"
    • Qian, Z.M. and Ke, Y. (2001) "Rethinking the role of ceruloplasmin in brain iron metabolism", Brain Res. Rev. 35, 287-294.
    • (2001) Brain Res. Rev. , vol.35 , pp. 287-294
    • Qian, Z.M.1    Ke, Y.2
  • 181
    • 0035095564 scopus 로고    scopus 로고
    • "Brain iron transport and neurodegeneration"
    • Qian, Z.M. and Shen, X. (2001) "Brain iron transport and neurodegeneration", Trends Mol. Med. 7, 103-108.
    • (2001) Trends Mol. Med. , vol.7 , pp. 103-108
    • Qian, Z.M.1    Shen, X.2
  • 182
    • 0010487727 scopus 로고    scopus 로고
    • "Expression of iron transport proteins and excessive iron accumulation in the brain in neurodegenerative disorders"
    • Qian, Z.M. and Wang, Q. (1998) "Expression of iron transport proteins and excessive iron accumulation in the brain in neurodegenerative disorders", Brain Res. Rev. 27, 257-267.
    • (1998) Brain Res. Rev. , vol.27 , pp. 257-267
    • Qian, Z.M.1    Wang, Q.2
  • 183
    • 0035526326 scopus 로고    scopus 로고
    • "Late-onset neurodegeneration with brain iron accumulation type 1: Expanding the clinical spectrum"
    • Racette, B.A., Perry, A., D'Avossa, G. and Perlmutter, J.S. (2001) "Late-onset neurodegeneration with brain iron accumulation type 1: expanding the clinical spectrum", Mov. Disord. 16, 1148-1152.
    • (2001) Mov. Disord. , vol.16 , pp. 1148-1152
    • Racette, B.A.1    Perry, A.2    D'Avossa, G.3    Perlmutter, J.S.4
  • 184
    • 0033582421 scopus 로고    scopus 로고
    • "The yeast frataxin homologue mediates mitochondrial iron efflux: Evidence for a mitochondrial iron cycle"
    • Radisky, D.C., Bacock, M.C. and Kaplan, J. (1999) "The yeast frataxin homologue mediates mitochondrial iron efflux: evidence for a mitochondrial iron cycle", J. Biol. Chem. 274, 4497-4499.
    • (1999) J. Biol. Chem. , vol.274 , pp. 4497-4499
    • Radisky, D.C.1    Bacock, M.C.2    Kaplan, J.3
  • 186
    • 0031573468 scopus 로고    scopus 로고
    • "Stimulation of the ferroxidase activity of ceruloplasmin during the iron loading into ferritin"
    • Reilly, C.A. and Aust, S.D. (1997) "Stimulation of the ferroxidase activity of ceruloplasmin during the iron loading into ferritin", Arch. Biochem. Biophys. 347, 242-248.
    • (1997) Arch. Biochem. Biophys. , vol.347 , pp. 242-248
    • Reilly, C.A.1    Aust, S.D.2
  • 189
    • 0026625534 scopus 로고
    • "Distribution of iron in different brain regions and subcellular compartments in Parkinson's disease"
    • Riederer, P., Dirr, A., Goetz, M., Sofic, E., Jellinger, K. and Youdim, M.B. (1992) "Distribution of iron in different brain regions and subcellular compartments in Parkinson's disease", Ann. Neurol. 32, 101-104.
    • (1992) Ann. Neurol. , vol.32 , pp. 101-104
    • Riederer, P.1    Dirr, A.2    Goetz, M.3    Sofic, E.4    Jellinger, K.5    Youdim, M.B.6
  • 190
    • 0033954772 scopus 로고    scopus 로고
    • "Pantothenate kinase regulation of the intracellular concentration of coenzym A"
    • Rock, C.O., Calder, R.B., Karim, M.A. and Jackowski, S. (2000) "Pantothenate kinase regulation of the intracellular concentration of coenzym A", J. Biol. Chem. 14, 1377-1383.
    • (2000) J. Biol. Chem. , vol.14 , pp. 1377-1383
    • Rock, C.O.1    Calder, R.B.2    Karim, M.A.3    Jackowski, S.4
  • 193
    • 0034839086 scopus 로고    scopus 로고
    • "Systemic iron metabolism: A review and implications for brain iron metabolism"
    • Rouault, T. (2001) "Systemic iron metabolism: a review and implications for brain iron metabolism", Pediatr. Neurol. 25, 130-137.
    • (2001) Pediatr. Neurol. , vol.25 , pp. 130-137
    • Rouault, T.1
  • 196
    • 0029054075 scopus 로고
    • "Magnetic resonance imaging evidence of decreased putamenal iron content in idiopathic Parkinson's disease"
    • Ryvlin, P., Broussolle, E., Piollet, H., Viallet, F., Khalfallah, Y. and Chazot, G. (1995) "Magnetic resonance imaging evidence of decreased putamenal iron content in idiopathic Parkinson's disease", Arch. Neurol. 52, 583-588.
    • (1995) Arch. Neurol. , vol.52 , pp. 583-588
    • Ryvlin, P.1    Broussolle, E.2    Piollet, H.3    Viallet, F.4    Khalfallah, Y.5    Chazot, G.6
  • 199
    • 0028183613 scopus 로고
    • "Magnetic resonance imaging in progressive supranuclear palsy and other parkinsonian disorders"
    • Savoreido, M., Girotti, F., Strada, L. and Ciceri, E. (1994) "Magnetic resonance imaging in progressive supranuclear palsy and other parkinsonian disorders", J. Neural Transm. Suppl. 42, 93-110.
    • (1994) J. Neural Transm. Suppl. , vol.42 , pp. 93-110
    • Savoreido, M.1    Girotti, F.2    Strada, L.3    Ciceri, E.4
  • 200
    • 0030989545 scopus 로고    scopus 로고
    • "4-Hydroxynonenal-derived advanced lipid peroxidation end products increased in Alzheimer's disease"
    • Sayre, L.M., Zelasko, D.A., Harris, P.L.R., Perry, G., Salomon, R.G. and Smith, M.A. (1997) "4-Hydroxynonenal-derived advanced lipid peroxidation end products increased in Alzheimer's disease", J. Neurochem. 68, 2092-2097.
    • (1997) J. Neurochem. , vol.68 , pp. 2092-2097
    • Sayre, L.M.1    Zelasko, D.A.2    Harris, P.L.R.3    Perry, G.4    Salomon, R.G.5    Smith, M.A.6
  • 201
  • 202
    • 0033964859 scopus 로고    scopus 로고
    • "In situ oxidative calalysis by neurofibrillary tangles and senile palques in Alzheimer's disease: A central role for bound transition metals"
    • Sayre, L.M., Perry, G., Harris, P.L., Liu, Y., Schubert, K.A. and Smith, M.A. (2000) "In situ oxidative calalysis by neurofibrillary tangles and senile palques in Alzheimer's disease: a central role for bound transition metals", J. Neurochem. 74, 270-279.
    • (2000) J. Neurochem. , vol.74 , pp. 270-279
    • Sayre, L.M.1    Perry, G.2    Harris, P.L.3    Liu, Y.4    Schubert, K.A.5    Smith, M.A.6
  • 203
    • 0033793044 scopus 로고    scopus 로고
    • "Heme oxygenase-1: Role in brain aging and neurodegeneration"
    • Schipper, H.M. (2000) "Heme oxygenase-1: role in brain aging and neurodegeneration", Exp. Gerontol. 35, 821-830.
    • (2000) Exp. Gerontol. , vol.35 , pp. 821-830
    • Schipper, H.M.1
  • 204
    • 0032740768 scopus 로고    scopus 로고
    • "A mutation in a mitochondrial ABC transporter results in mitochondrial dysfunction through oxidative damage of mitochondrial DNA"
    • Senbongi, H., Ling, F. and Shibata, T. (1999) "A mutation in a mitochondrial ABC transporter results in mitochondrial dysfunction through oxidative damage of mitochondrial DNA", Mol. Gen. Genet. 262, 426-436.
    • (1999) Mol. Gen. Genet. , vol.262 , pp. 426-436
    • Senbongi, H.1    Ling, F.2    Shibata, T.3
  • 205
    • 0034006860 scopus 로고    scopus 로고
    • "Geneticdisorders affecting proteins of iron metabolism: Clinical implications"
    • Sheth, S. and Briitenham, G.M. (2000) "Geneticdisorders affecting proteins of iron metabolism: clinical implications", Ann. Rev. Med. 51, 443-464.
    • (2000) Ann. Rev. Med. , vol.51 , pp. 443-464
    • Sheth, S.1    Briitenham, G.M.2
  • 207
    • 1642555537 scopus 로고    scopus 로고
    • "Iron involvement in neural damage and microgliosis in models of neurodegerative disorders"
    • Shoham, S. and Youdim, M.B. (2000) "Iron involvement in neural damage and microgliosis in models of neurodegerative disorders", Cell Mol. Biol. 46, 743-760.
    • (2000) Cell Mol. Biol. , vol.46 , pp. 743-760
    • Shoham, S.1    Youdim, M.B.2
  • 208
    • 0346386580 scopus 로고    scopus 로고
    • "Widespread peroxynitrite-mediated damage in Alzheimer's disease"
    • Smith, M.A., Harris, P.L.R., Sayre, L.M., Beckmann, J.S. and Perry, G. (1997) "Widespread peroxynitrite-mediated damage in Alzheimer's disease", J. Neurosci. 17, 2653-2657.
    • (1997) J. Neurosci. , vol.17 , pp. 2653-2657
    • Smith, M.A.1    Harris, P.L.R.2    Sayre, L.M.3    Beckmann, J.S.4    Perry, G.5
  • 210
    • 0032584686 scopus 로고    scopus 로고
    • "Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies"
    • Spillantini, M.G., Crowther, R.A., Jakes, R., Cairns, N.J., Lantos, P.L. and Goedert, M. (1998) "Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies", Neurosci. Lett. 251, 205-208.
    • (1998) Neurosci. Lett. , vol.251 , pp. 205-208
    • Spillantini, M.G.1    Crowther, R.A.2    Jakes, R.3    Cairns, N.J.4    Lantos, P.L.5    Goedert, M.6
  • 211
    • 0026317374 scopus 로고
    • "Hallervorden-Spatz syndrome and brain iron metabolism"
    • Swaiman, K.F. (1991) "Hallervorden-Spatz syndrome and brain iron metabolism", Arch. Neurol. 48, 1285-1293.
    • (1991) Arch. Neurol. , vol.48 , pp. 1285-1293
    • Swaiman, K.F.1
  • 212
    • 0034838767 scopus 로고    scopus 로고
    • "Hallervorden-Spatz syndrome"
    • Swaiman, K.F. (2001) "Hallervorden-Spatz syndrome", Pediatr. Neurol. 25, 102-108.
    • (2001) Pediatr. Neurol. , vol.25 , pp. 102-108
    • Swaiman, K.F.1
  • 214
    • 0034698023 scopus 로고    scopus 로고
    • "Human NRAMP2/DMT1, which mediates iron transport across endosomal membranes, is localized to late endosomes and lysosomes in Hep-2 cells"
    • Tabucchi, M., Yoshimori, T., Yamaguchi, K., Yoshida, T. and Kishi, F. (2000) "Human NRAMP2/DMT1, which mediates iron transport across endosomal membranes, is localized to late endosomes and lysosomes in Hep-2 cells", J. Biol. Chem. 21, 22220-22228.
    • (2000) J. Biol. Chem. , vol.21 , pp. 22220-22228
    • Tabucchi, M.1    Yoshimori, T.2    Yamaguchi, K.3    Yoshida, T.4    Kishi, F.5
  • 217
    • 0023067301 scopus 로고
    • "Ferritin; structure, gene regulation, and cellular function in animals, plants and microorganisms"
    • Theil, E.C. (1987) "Ferritin; structure, gene regulation, and cellular function in animals, plants and microorganisms", Annu. Rev. Biochem. 56, 289-315.
    • (1987) Annu. Rev. Biochem. , vol.56 , pp. 289-315
    • Theil, E.C.1
  • 218
    • 0033990290 scopus 로고    scopus 로고
    • "Targeting mRNA to regulate iron and oxygen metabolism"
    • Theil, E.C. (2000) "Targeting mRNA to regulate iron and oxygen metabolism", Biochem. Pharmacol. 59, 87-93.
    • (2000) Biochem. Pharmacol. , vol.59 , pp. 87-93
    • Theil, E.C.1
  • 220
    • 0032909207 scopus 로고    scopus 로고
    • "Hephaestin, a ceruloplasmin homologue implicated in intestinal iron transport, is defective in the sla mouse"
    • Vulpe, C.D., Kuo, Y.M., Murphy, L., Cowley, L., Askwith, C., Libina, N., Gitschier, J. and Anderson, G.J. (1999) "Hephaestin, a ceruloplasmin homologue implicated in intestinal iron transport, is defective in the sla mouse", Nat. Genet. 21, 195-199.
    • (1999) Nat. Genet. , vol.21 , pp. 195-199
    • Vulpe, C.D.1    Kuo, Y.M.2    Murphy, L.3    Cowley, L.4    Askwith, C.5    Libina, N.6    Gitschier, J.7    Anderson, G.J.8
  • 221
    • 0033045138 scopus 로고    scopus 로고
    • "T1 and T2 in the brain of healthy subjects, patients with Pakinson disease and patients with multiple system atrophy: Relation to iron content"
    • Vymazal, J., Righini, A., Brooks, R.A., Canesi, M., Mariani, C., Leonardi, M. and Pezzoli, G. (1999) "T1 and T2 in the brain of healthy subjects, patients with Pakinson disease and patients with multiple system atrophy: relation to iron content", Radiology 211, 489-495.
    • (1999) Radiology , vol.211 , pp. 489-495
    • Vymazal, J.1    Righini, A.2    Brooks, R.A.3    Canesi, M.4    Mariani, C.5    Leonardi, M.6    Pezzoli, G.7
  • 222
    • 0032971328 scopus 로고    scopus 로고
    • "Increased iron content in the dentate nucleus of patients with Friedreich's ataxia"
    • Waldvogel, D., van Gelderen, M. and Hallett, M. (1999) "Increased iron content in the dentate nucleus of patients with Friedreich's ataxia", Ann. Neurol. 46, 123-135.
    • (1999) Ann. Neurol. , vol.46 , pp. 123-135
    • Waldvogel, D.1    van Gelderen, M.2    Hallett, M.3
  • 223
  • 224
    • 0031903392 scopus 로고    scopus 로고
    • "Normal serum iron and ferritin concentrations in patients with Friedreich's ataxia"
    • Wilson, R.B., Lynch, D.R. and Fischbeck, K.H. (1998) "Normal serum iron and ferritin concentrations in patients with Friedreich's ataxia", Ann. Neurol. 44, 132-134.
    • (1998) Ann. Neurol. , vol.44 , pp. 132-134
    • Wilson, R.B.1    Lynch, D.R.2    Fischbeck, K.H.3
  • 225
    • 0034014830 scopus 로고    scopus 로고
    • "Increased serum transferrin receptor concentrations in Friedreich ataxia"
    • Wilson, R.B., Lynch, D.R., Farmer, J.M., Brooks, D.G. and Fischbeck, K.H. (2000) "Increased serum transferrin receptor concentrations in Friedreich ataxia", Ann. Neurol. 47, 659-661.
    • (2000) Ann. Neurol. , vol.47 , pp. 659-661
    • Wilson, R.B.1    Lynch, D.R.2    Farmer, J.M.3    Brooks, D.G.4    Fischbeck, K.H.5
  • 229
    • 0027722145 scopus 로고
    • "Concentration of zinc and iron in the brains of Guamanian patients with amytrophic lateral sclerosis and parkinsonism-demetia"
    • Yasui, M., Ota, K. and Garruto, R.M. (1993) "Concentration of zinc and iron in the brains of Guamanian patients with amytrophic lateral sclerosis and parkinsonism-demetia", Neurotoxicology 14, 445-450.
    • (1993) Neurotoxicology , vol.14 , pp. 445-450
    • Yasui, M.1    Ota, K.2    Garruto, R.M.3
  • 230
    • 0002731550 scopus 로고    scopus 로고
    • "Copper, zinc superoxide dismutase enhances DNA damage and mutagenicity induced by cystein/iron"
    • Yoon, S.J., Koh, Y.H., Floyd, R.A. and Park, J.W. (2000) "Copper, zinc superoxide dismutase enhances DNA damage and mutagenicity induced by cystein/iron", Mutat. Res. 448, 97-104.
    • (2000) Mutat. Res. , vol.448 , pp. 97-104
    • Yoon, S.J.1    Koh, Y.H.2    Floyd, R.A.3    Park, J.W.4
  • 231
    • 0028917342 scopus 로고
    • "Activated microglia cause superoxide-mediated release of iron from ferritin"
    • Yoshida, T., Tanaka, M., Sotomatsu, A. and Hirai, S. (1995) "Activated microglia cause superoxide-mediated release of iron from ferritin", Neurosci. Lett. 190, 21-24.
    • (1995) Neurosci. Lett. , vol.190 , pp. 21-24
    • Yoshida, T.1    Tanaka, M.2    Sotomatsu, A.3    Hirai, S.4
  • 233
    • 0025736680 scopus 로고
    • "Iron in brain function and dysfunction with emphasis on Parkinson's disease"
    • Youdim, M., Ben-Shachar, D. and Riederer, P. (1991) "Iron in brain function and dysfunction with emphasis on Parkinson's disease", Eur. Neurol. 31, 34-40.
    • (1991) Eur. Neurol. , vol.31 , pp. 34-40
    • Youdim, M.1    Ben-Shachar, D.2    Riederer, P.3
  • 234
    • 0030641754 scopus 로고    scopus 로고
    • "Understanding Parkinson's disease"
    • Youdim, M.B. and Riederer, P. (1997) "Understanding Parkinson's disease", Sci. Am. 276, 52-59.
    • (1997) Sci. Am. , vol.276 , pp. 52-59
    • Youdim, M.B.1    Riederer, P.2
  • 235
    • 0030854755 scopus 로고    scopus 로고
    • "Ceruloplasmin, transferrin and apotransferrin facilitate iron release from human liver cells"
    • Young, S.P., Fahmy, M. and Golding, S. (1997) "Ceruloplasmin, transferrin and apotransferrin facilitate iron release from human liver cells", FEBS Lett. 411, 93-96.
    • (1997) FEBS Lett. , vol.411 , pp. 93-96
    • Young, S.P.1    Fahmy, M.2    Golding, S.3
  • 237
    • 0035103932 scopus 로고    scopus 로고
    • "Iron, neuromelanin and ferritin in substantia nigra of normal subjects at different ages: Consequences for iron storage and neurodegenerative processes"
    • Zecca, L., Gallorini, M., Schünemann, V., Trautwein, A.X., Gerlach, M., Riederer, P., Vezzoni, P. and Tampellini, D. (2001) "Iron, neuromelanin and ferritin in substantia nigra of normal subjects at different ages: consequences for iron storage and neurodegenerative processes", J. Neurochem. 76, 1766-1773.
    • (2001) J. Neurochem. , vol.76 , pp. 1766-1773
    • Zecca, L.1    Gallorini, M.2    Schünemann, V.3    Trautwein, A.X.4    Gerlach, M.5    Riederer, P.6    Vezzoni, P.7    Tampellini, D.8
  • 238
    • 0034024975 scopus 로고    scopus 로고
    • "Interaction of human substantia nigra neuromelanin with lipids and peptides"
    • Zecca, L., Costi, P., Mecacci, C., Ito, S., Terreni, M. and Sonnino, S. (2000) "Interaction of human substantia nigra neuromelanin with lipids and peptides", J. Neurochem. 74, 1758-1765.
    • (2000) J. Neurochem. , vol.74 , pp. 1758-1765
    • Zecca, L.1    Costi, P.2    Mecacci, C.3    Ito, S.4    Terreni, M.5    Sonnino, S.6
  • 239
    • 0037116582 scopus 로고    scopus 로고
    • "The absolute concentration of nigral neuromelanin, assayed by a new sensitive method, increases throughout the life and is dramatically decreased in Parkinson's disease"
    • Zecca, L., Fariello, R., Riederer, P., Sulzer, D., Gatti, A. and Tampellini, D. (2002) "The absolute concentration of nigral neuromelanin, assayed by a new sensitive method, increases throughout the life and is dramatically decreased in Parkinson's disease", FEBS Lett. 510, 216-220.
    • (2002) FEBS Lett. , vol.510 , pp. 216-220
    • Zecca, L.1    Fariello, R.2    Riederer, P.3    Sulzer, D.4    Gatti, A.5    Tampellini, D.6
  • 240
    • 0034935036 scopus 로고    scopus 로고
    • "A novel pantothenate kinase gene (PANK2). is defective in Hallervorden-Spatz syndrome"
    • Zhou, B., Westaway, S.K., Levinson, B., Johnson, M.A., Gitschier, J. and Hayflick, S.J. (2001) "A novel pantothenate kinase gene (PANK2). is defective in Hallervorden-Spatz syndrome", Nat. Genet. 28, 345-349.
    • (2001) Nat. Genet. , vol.28 , pp. 345-349
    • Zhou, B.1    Westaway, S.K.2    Levinson, B.3    Johnson, M.A.4    Gitschier, J.5    Hayflick, S.J.6
  • 241
    • 0025166102 scopus 로고
    • "Osmiophilic deposits in cytosomes in Hallervorden-Spatz syndrome"
    • Zupanc, M.L., Chun, R.W.M. and Gilbert-Barness, E.F. (1990) "Osmiophilic deposits in cytosomes in Hallervorden-Spatz syndrome", Pediatr. Neurol. 6, 345-352.
    • (1990) Pediatr. Neurol. , vol.6 , pp. 345-352
    • Zupanc, M.L.1    Chun, R.W.M.2    Gilbert-Barness, E.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.