-
1
-
-
0026303274
-
The role of DNA double strand breaks in ionizing radiation induced killing of eukaryotic cells
-
G. Iliakis, The role of DNA double strand breaks in ionizing radiation induced killing of eukaryotic cells. BioEssays 13, 641-648 (1991).
-
(1991)
BioEssays
, vol.13
, pp. 641-648
-
-
Iliakis, G.1
-
2
-
-
0025368957
-
Studies on mammalian mutants defective in rejoining double-strand breaks
-
P. A. Jeggo, Studies on mammalian mutants defective in rejoining double-strand breaks. Mutat. Res. 239, 1-16 (1990).
-
(1990)
Mutat. Res.
, vol.239
, pp. 1-16
-
-
Jeggo, P.A.1
-
3
-
-
0029395076
-
Menage á trois: Double strand break repair, V(D)J recombination and DNA-PK
-
P. A. Jeggo, G. E. Taccioli and S. P. Jackson. Menage á trois: Double strand break repair, V(D)J recombination and DNA-PK. BioEssays 17, 949-957 (1995).
-
(1995)
BioEssays
, vol.17
, pp. 949-957
-
-
Jeggo, P.A.1
Taccioli, G.E.2
Jackson, S.P.3
-
4
-
-
0029117310
-
What to do at an end: DNA double-strand-break repair
-
D. T. Weaver, What to do at an end: DNA double-strand-break repair. Trends Genet. 11, 388-392 (1995).
-
(1995)
Trends Genet.
, vol.11
, pp. 388-392
-
-
Weaver, D.T.1
-
5
-
-
0027397867
-
The DNA-dependent protein kinase: Requirement for DNA ends and association with Ku antigen
-
T. M. Gottlieb and S. P. Jackson, The DNA-dependent protein kinase: Requirement for DNA ends and association with Ku antigen. Cell 72, 131-142 (1993).
-
(1993)
Cell
, vol.72
, pp. 131-142
-
-
Gottlieb, T.M.1
Jackson, S.P.2
-
6
-
-
0023018810
-
Characterization of the DNA-binding protein antigen Ku recognized by autoantibodies from patients with rheumatic disorders
-
T. Mimori, J. A. Hardin and J. A. Steitz, Characterization of the DNA-binding protein antigen Ku recognized by autoantibodies from patients with rheumatic disorders. J. Biol. Chem. 261, 2274-2278 (1986).
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 2274-2278
-
-
Mimori, T.1
Hardin, J.A.2
Steitz, J.A.3
-
7
-
-
0024524581
-
Molecular cloning of cDNA encoding the p70 (Ku) lupus autoantigen
-
W. H. Reeves and Z. M. Sthoeger, Molecular cloning of cDNA encoding the p70 (Ku) lupus autoantigen. J. Biol. Chem. 264, 5047-5052 (1989).
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 5047-5052
-
-
Reeves, W.H.1
Sthoeger, Z.M.2
-
8
-
-
0030339852
-
The DNA-dependent protein kinase, DNA-PK: 10 years and no ends in sight
-
S. P. Lees-Miller, The DNA-dependent protein kinase, DNA-PK: 10 years and no ends in sight. Biochem. Cell Biol. 74, 503-512 (1996).
-
(1996)
Biochem. Cell Biol.
, vol.74
, pp. 503-512
-
-
Lees-Miller, S.P.1
-
9
-
-
0029778191
-
Requirement for Ku80 in growth and immunoglobulin V(D)J recombination
-
A. Nussenzweig, C. Chen, V. da Costa Soares, M. Sanchez, K. Sokol, M. C. Nussenzweig and G. C. Li, Requirement for Ku80 in growth and immunoglobulin V(D)J recombination. Nature 382, 551-555 (1996).
-
(1996)
Nature
, vol.382
, pp. 551-555
-
-
Nussenzweig, A.1
Chen, C.2
Da Costa Soares, V.3
Sanchez, M.4
Sokol, K.5
Nussenzweig, M.C.6
Li, G.C.7
-
10
-
-
0030576534
-
Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates
-
C. Zhu, M. A. Bogue, D-S. Lim, P. Hasty and D. B. Roth, Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates. Cell 86, 379-389 (1996).
-
(1996)
Cell
, vol.86
, pp. 379-389
-
-
Zhu, C.1
Bogue, M.A.2
Lim, D.-S.3
Hasty, P.4
Roth, D.B.5
-
11
-
-
0026584193
-
Level of DNA double-strand break rejoining in Chinese hamster xrs-5 cells is dose-dependent: Implications for the mechanism of radiosensitivity
-
G. Iliakis, R. Mehta and M. Jackson, Level of DNA double-strand break rejoining in Chinese hamster xrs-5 cells is dose-dependent: Implications for the mechanism of radiosensitivity. Int. J. Radiat. Biol. 61, 315-321 (1992).
-
(1992)
Int. J. Radiat. Biol.
, vol.61
, pp. 315-321
-
-
Iliakis, G.1
Mehta, R.2
Jackson, M.3
-
12
-
-
0027512522
-
Characterization of the DNA double strand break repair defect in scid mice
-
C. Chang, K. A. Biedermann, M. Mezzina and J. M. Brown, Characterization of the DNA double strand break repair defect in scid mice. Cancer Res. 53, 1244-1248 (1993).
-
(1993)
Cancer Res.
, vol.53
, pp. 1244-1248
-
-
Chang, C.1
Biedermann, K.A.2
Mezzina, M.3
Brown, J.M.4
-
14
-
-
0025980247
-
Detection of DNA double strand breaks in synchronous cultures of CHO cells by means of asymmetric field inversion gel electrophoresis
-
G. Iliakis, L. Metzger, N. Denko and T. D. Stamato, Detection of DNA double strand breaks in synchronous cultures of CHO cells by means of asymmetric field inversion gel electrophoresis. Int. J. Radiat. Biol. 59, 321-341 (1991).
-
(1991)
Int. J. Radiat. Biol.
, vol.59
, pp. 321-341
-
-
Iliakis, G.1
Metzger, L.2
Denko, N.3
Stamato, T.D.4
-
15
-
-
0025739820
-
Kinetics of DNA double strand breaks throughout the cell cycle as assayed by pulsed field gel electrophoresis in CHO cells
-
L. Metzger and G. Iliakis, Kinetics of DNA double strand breaks throughout the cell cycle as assayed by pulsed field gel electrophoresis in CHO cells. Int. J. Radiat. Biol. 59, 1325-1339 (1991).
-
(1991)
Int. J. Radiat. Biol.
, vol.59
, pp. 1325-1339
-
-
Metzger, L.1
Iliakis, G.2
-
16
-
-
0024582342
-
An asymmetric field inversion gel electrophoresis method for the separation of large DNA molecules
-
N. Denko, A. Giaccia, B. Peters and T. D. Stamato, An asymmetric field inversion gel electrophoresis method for the separation of large DNA molecules. Anal. Biochem. 178, 172-176 (1989).
-
(1989)
Anal. Biochem.
, vol.178
, pp. 172-176
-
-
Denko, N.1
Giaccia, A.2
Peters, B.3
Stamato, T.D.4
-
17
-
-
0026027189
-
Direct measurement by pulsed-field gel electrophoresis of induction and rejoining of X-ray-induced double-strand breaks in cultured mouse cells
-
S. Y. Ahn, B. Nevaldine and P. J. Hahn, Direct measurement by pulsed-field gel electrophoresis of induction and rejoining of X-ray-induced double-strand breaks in cultured mouse cells. Int. J. Radiat. Biol. 59, 661-675 (1991).
-
(1991)
Int. J. Radiat. Biol.
, vol.59
, pp. 661-675
-
-
Ahn, S.Y.1
Nevaldine, B.2
Hahn, P.J.3
-
18
-
-
0031030223
-
An assay for quantifying DNA double-strand break repair that is suitable for small numbers of unlabeled cells
-
J. A. Longo, B. Nevaldine, S. L. Longo, J. A. Winfield and P. J. Hahn, An assay for quantifying DNA double-strand break repair that is suitable for small numbers of unlabeled cells. Radiat. Res. 147, 35-40 (1997).
-
(1997)
Radiat. Res.
, vol.147
, pp. 35-40
-
-
Longo, J.A.1
Nevaldine, B.2
Longo, S.L.3
Winfield, J.A.4
Hahn, P.J.5
-
19
-
-
0030885974
-
Ku70 is required for DNA repair but not for T cell antigen receptor gene recombination in vivo
-
B. H. Ouyang, A. Nussenzweig, A. Kurimasa, D. C. Soares, X. Li, C. Cordon-Cardo, W-H. Li, N. Cheong, M. Nussenzweig, G. Iliakis, D. J. Chen and G. C. Li, Ku70 is required for DNA repair but not for T cell antigen receptor gene recombination in vivo. J. Exp. Med. 186, 921-929 (1997).
-
(1997)
J. Exp. Med.
, vol.186
, pp. 921-929
-
-
Ouyang, B.H.1
Nussenzweig, A.2
Kurimasa, A.3
Soares, D.C.4
Li, X.5
Cordon-Cardo, C.6
Li, W.-H.7
Cheong, N.8
Nussenzweig, M.9
Iliakis, G.10
Chen, D.J.11
Li, G.C.12
-
20
-
-
0021063154
-
X-ray-sensitive mutants of Chinese hamster ovary cell line. Isolation and cross-sensitivity to other DNA-damaging agents
-
P. A. Jeggo and L. M. Kemp, X-ray-sensitive mutants of Chinese hamster ovary cell line. Isolation and cross-sensitivity to other DNA-damaging agents. Mutat. Res. 112, 313-327 (1983).
-
(1983)
Mutat. Res.
, vol.112
, pp. 313-327
-
-
Jeggo, P.A.1
Kemp, L.M.2
-
21
-
-
0024596693
-
Biphasic survival curves for XRS radiosensitive cells: Subpopulations or transient expression of repair competence?
-
J. Denekamp, G. F. Whitmore and P. Jeggo, Biphasic survival curves for XRS radiosensitive cells: Subpopulations or transient expression of repair competence? Int. J. Radiat. Biol. 55, 605-617 (1989).
-
(1989)
Int. J. Radiat. Biol.
, vol.55
, pp. 605-617
-
-
Denekamp, J.1
Whitmore, G.F.2
Jeggo, P.3
-
22
-
-
0022994407
-
Azacytidine-induced reactivation of a DNA repair gene in Chinese hamster ovary cells
-
P. A. Jeggo and R. Holliday, Azacytidine-induced reactivation of a DNA repair gene in Chinese hamster ovary cells. Mol. Cell. Biol. 6, 2944-2949 (1986).
-
(1986)
Mol. Cell. Biol.
, vol.6
, pp. 2944-2949
-
-
Jeggo, P.A.1
Holliday, R.2
-
23
-
-
0030926490
-
The scid defect results in much slower repair of DNA double-strand breaks but not high levels of residual breaks
-
B. Nevaldine, J. A. Longo and P. J. Hahn, The scid defect results in much slower repair of DNA double-strand breaks but not high levels of residual breaks. Radiat. Res. 147, 535-540 (1997).
-
(1997)
Radiat. Res.
, vol.147
, pp. 535-540
-
-
Nevaldine, B.1
Longo, J.A.2
Hahn, P.J.3
-
24
-
-
0028025020
-
Ku80: Product of the XRCC5 gene and its role in DNA repair and V(D)J recombination
-
G. E. Taccioli, T. M. Gottlieb, T. Blunt, A. Priestley, J. Demengeot, R. Mizuta, A. R. Lehmann, F. W. Alt, S. P. Jackson and P. A. Jeggo, Ku80: Product of the XRCC5 gene and its role in DNA repair and V(D)J recombination. Science 265, 1442-1445 (1994).
-
(1994)
Science
, vol.265
, pp. 1442-1445
-
-
Taccioli, G.E.1
Gottlieb, T.M.2
Blunt, T.3
Priestley, A.4
Demengeot, J.5
Mizuta, R.6
Lehmann, A.R.7
Alt, F.W.8
Jackson, S.P.9
Jeggo, P.A.10
-
25
-
-
0026071588
-
Scid mutation in mice confers hypersensitivity to ionizing radiation and a deficiency in DNA double-strand break repair
-
K. A. Biedermann, J. Sung, A. J. Giaccia, L. M. Tosto and J. M. Brown, scid mutation in mice confers hypersensitivity to ionizing radiation and a deficiency in DNA double-strand break repair. Proc. Natl. Acad. Sci. USA 88, 1394-1397 (1991).
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 1394-1397
-
-
Biedermann, K.A.1
Sung, J.2
Giaccia, A.J.3
Tosto, L.M.4
Brown, J.M.5
-
26
-
-
0028953951
-
DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect
-
C. U. Kirchgessner, C. K. Patil, J. W. Evans, C. A. Cuomo, L. M. Fried, T. Carter, M. A. Oettinger and J. M. Brown, DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect. Science 267, 1178-1183 (1995).
-
(1995)
Science
, vol.267
, pp. 1178-1183
-
-
Kirchgessner, C.U.1
Patil, C.K.2
Evans, J.W.3
Cuomo, C.A.4
Fried, L.M.5
Carter, T.6
Oettinger, M.A.7
Brown, J.M.8
-
27
-
-
0025734394
-
Fibroblasts from ataxia telangiectasia (AT) and AT heterozygotes show an enhanced level of residual DNA double-strand breaks after low dose-rate γ-irradiation as assayed by pulsed field gel electrophoresis
-
D. Blöcher, D. Sigut and M. A. Hannan, Fibroblasts from ataxia telangiectasia (AT) and AT heterozygotes show an enhanced level of residual DNA double-strand breaks after low dose-rate γ-irradiation as assayed by pulsed field gel electrophoresis. Int. J. Radiat. Biol. 60, 791-802 (1991).
-
(1991)
Int. J. Radiat. Biol.
, vol.60
, pp. 791-802
-
-
Blöcher, D.1
Sigut, D.2
Hannan, M.A.3
-
28
-
-
0028363754
-
Absence of a Ku-like DNA end binding activity in the xrs double-strand DNA repair-deficient mutant
-
R. C. Getts and T. D. Stamato, Absence of a Ku-like DNA end binding activity in the xrs double-strand DNA repair-deficient mutant. J. Biol. Chem. 269, 15981-15984 (1994).
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 15981-15984
-
-
Getts, R.C.1
Stamato, T.D.2
-
29
-
-
0028342645
-
A DNA end-binding factor involved in double strand break repair and V(D)J recombination
-
W. K. Rathmell and G. A. Chu, A DNA end-binding factor involved in double strand break repair and V(D)J recombination. Mol. Cell. Biol. 14, 4741-4748 (1994).
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 4741-4748
-
-
Rathmell, W.K.1
Chu, G.A.2
-
31
-
-
0028897304
-
DNA-dependent protein kinase activity is absent in xrs-6 cells: Implications for site-specific recombination and DNA double-strand break repair
-
N. J. Finnie, T. M. Gottlieb, T. Blunt, P. A. Jeggo and S. P. Jackson, DNA-dependent protein kinase activity is absent in xrs-6 cells: Implications for site-specific recombination and DNA double-strand break repair. Proc. Natl. Acad. Sci. USA 92, 320-324 (1995).
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 320-324
-
-
Finnie, N.J.1
Gottlieb, T.M.2
Blunt, T.3
Jeggo, P.A.4
Jackson, S.P.5
-
32
-
-
0029156599
-
DNA-dependent protein kinase catalytic subunit: A relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product
-
K. O. Hartley, D. Gell, G. C. M. Smith, H. Zhang, N. Divecha, M. A. Connelly, A. Admon, S. P. Lees-Miller, C. W. Anderson and S. P. Jackson, DNA-dependent protein kinase catalytic subunit: A relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product. Cell 82, 849-856 (1995).
-
(1995)
Cell
, vol.82
, pp. 849-856
-
-
Hartley, K.O.1
Gell, D.2
Smith, G.C.M.3
Zhang, H.4
Divecha, N.5
Connelly, M.A.6
Admon, A.7
Lees-Miller, S.P.8
Anderson, C.W.9
Jackson, S.P.10
-
33
-
-
0028791446
-
DNA double-strand break repair and V(D)J recombination: Involvement of DNA-PK
-
S. P. Jackson and P. A. Jeggo, DNA double-strand break repair and V(D)J recombination: involvement of DNA-PK. Trends Biochem. Sci. 20, 412-415 (1995).
-
(1995)
Trends Biochem. Sci.
, vol.20
, pp. 412-415
-
-
Jackson, S.P.1
Jeggo, P.A.2
-
34
-
-
0028855064
-
DNA-dependent protein kinase: A potent inhibitor of transcription by RNA polymerase 1
-
A. Kuhn, T. M. Gottlieb, S. P. Jackson and I. Grummt, DNA-dependent protein kinase: A potent inhibitor of transcription by RNA polymerase 1. Genes Dev. 9, 193-203 (1995).
-
(1995)
Genes Dev.
, vol.9
, pp. 193-203
-
-
Kuhn, A.1
Gottlieb, T.M.2
Jackson, S.P.3
Grummt, I.4
-
35
-
-
0031059531
-
Tying loose ends: Roles of Ku and DNA-dependent protein kinase in the repair of double-strand breaks
-
M. R. Lieber, U. Grawunder, X. Wu and M. Yaneva, Tying loose ends: Roles of Ku and DNA-dependent protein kinase in the repair of double-strand breaks, Curr. Opin. Genet. Dev. 7, 99-104 (1997).
-
(1997)
Curr. Opin. Genet. Dev.
, vol.7
, pp. 99-104
-
-
Lieber, M.R.1
Grawunder, U.2
Wu, X.3
Yaneva, M.4
-
36
-
-
0030475586
-
Mechanisms of nonhomologous DNA end-joining in frogs, mice and men
-
P. Daza, S. Reichenberger, B. Göttlich, M. Hagmann, E. Feldmann and P. Pfeiffer, Mechanisms of nonhomologous DNA end-joining in frogs, mice and men. J. biol. Chem. 377, 775-786 (1996).
-
(1996)
J. Biol. Chem.
, vol.377
, pp. 775-786
-
-
Daza, P.1
Reichenberger, S.2
Göttlich, B.3
Hagmann, M.4
Feldmann, E.5
Pfeiffer, P.6
-
37
-
-
0030592555
-
The identification and characterization of mammalian proteins involved in the rejoining of DNA double-strand breaks in vitro
-
A. P. Johnson and M. P. Fairman, The identification and characterization of mammalian proteins involved in the rejoining of DNA double-strand breaks in vitro. Mutat. Res. 364, 103-116 (1996).
-
(1996)
Mutat. Res.
, vol.364
, pp. 103-116
-
-
Johnson, A.P.1
Fairman, M.P.2
-
38
-
-
0030471390
-
The joining of noncomplementary DNA double-strand breaks by mammalian extracts
-
R. M. Mason, J. Thacker and M. P. Fairman, The joining of noncomplementary DNA double-strand breaks by mammalian extracts. Nucleic Acids Res. 24, 4946-4953 (1996).
-
(1996)
Nucleic Acids Res.
, vol.24
, pp. 4946-4953
-
-
Mason, R.M.1
Thacker, J.2
Fairman, M.P.3
|