메뉴 건너뛰기




Volumn 151, Issue 4, 1999, Pages 398-407

Rejoining of DNA double-strand breaks in Ku80-deficient mouse fibroblasts

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED DNA;

EID: 0032998125     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.2307/3579826     Document Type: Article
Times cited : (37)

References (38)
  • 1
    • 0026303274 scopus 로고
    • The role of DNA double strand breaks in ionizing radiation induced killing of eukaryotic cells
    • G. Iliakis, The role of DNA double strand breaks in ionizing radiation induced killing of eukaryotic cells. BioEssays 13, 641-648 (1991).
    • (1991) BioEssays , vol.13 , pp. 641-648
    • Iliakis, G.1
  • 2
    • 0025368957 scopus 로고
    • Studies on mammalian mutants defective in rejoining double-strand breaks
    • P. A. Jeggo, Studies on mammalian mutants defective in rejoining double-strand breaks. Mutat. Res. 239, 1-16 (1990).
    • (1990) Mutat. Res. , vol.239 , pp. 1-16
    • Jeggo, P.A.1
  • 3
    • 0029395076 scopus 로고
    • Menage á trois: Double strand break repair, V(D)J recombination and DNA-PK
    • P. A. Jeggo, G. E. Taccioli and S. P. Jackson. Menage á trois: Double strand break repair, V(D)J recombination and DNA-PK. BioEssays 17, 949-957 (1995).
    • (1995) BioEssays , vol.17 , pp. 949-957
    • Jeggo, P.A.1    Taccioli, G.E.2    Jackson, S.P.3
  • 4
    • 0029117310 scopus 로고
    • What to do at an end: DNA double-strand-break repair
    • D. T. Weaver, What to do at an end: DNA double-strand-break repair. Trends Genet. 11, 388-392 (1995).
    • (1995) Trends Genet. , vol.11 , pp. 388-392
    • Weaver, D.T.1
  • 5
    • 0027397867 scopus 로고
    • The DNA-dependent protein kinase: Requirement for DNA ends and association with Ku antigen
    • T. M. Gottlieb and S. P. Jackson, The DNA-dependent protein kinase: Requirement for DNA ends and association with Ku antigen. Cell 72, 131-142 (1993).
    • (1993) Cell , vol.72 , pp. 131-142
    • Gottlieb, T.M.1    Jackson, S.P.2
  • 6
    • 0023018810 scopus 로고
    • Characterization of the DNA-binding protein antigen Ku recognized by autoantibodies from patients with rheumatic disorders
    • T. Mimori, J. A. Hardin and J. A. Steitz, Characterization of the DNA-binding protein antigen Ku recognized by autoantibodies from patients with rheumatic disorders. J. Biol. Chem. 261, 2274-2278 (1986).
    • (1986) J. Biol. Chem. , vol.261 , pp. 2274-2278
    • Mimori, T.1    Hardin, J.A.2    Steitz, J.A.3
  • 7
    • 0024524581 scopus 로고
    • Molecular cloning of cDNA encoding the p70 (Ku) lupus autoantigen
    • W. H. Reeves and Z. M. Sthoeger, Molecular cloning of cDNA encoding the p70 (Ku) lupus autoantigen. J. Biol. Chem. 264, 5047-5052 (1989).
    • (1989) J. Biol. Chem. , vol.264 , pp. 5047-5052
    • Reeves, W.H.1    Sthoeger, Z.M.2
  • 8
    • 0030339852 scopus 로고    scopus 로고
    • The DNA-dependent protein kinase, DNA-PK: 10 years and no ends in sight
    • S. P. Lees-Miller, The DNA-dependent protein kinase, DNA-PK: 10 years and no ends in sight. Biochem. Cell Biol. 74, 503-512 (1996).
    • (1996) Biochem. Cell Biol. , vol.74 , pp. 503-512
    • Lees-Miller, S.P.1
  • 10
    • 0030576534 scopus 로고    scopus 로고
    • Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates
    • C. Zhu, M. A. Bogue, D-S. Lim, P. Hasty and D. B. Roth, Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates. Cell 86, 379-389 (1996).
    • (1996) Cell , vol.86 , pp. 379-389
    • Zhu, C.1    Bogue, M.A.2    Lim, D.-S.3    Hasty, P.4    Roth, D.B.5
  • 11
    • 0026584193 scopus 로고
    • Level of DNA double-strand break rejoining in Chinese hamster xrs-5 cells is dose-dependent: Implications for the mechanism of radiosensitivity
    • G. Iliakis, R. Mehta and M. Jackson, Level of DNA double-strand break rejoining in Chinese hamster xrs-5 cells is dose-dependent: Implications for the mechanism of radiosensitivity. Int. J. Radiat. Biol. 61, 315-321 (1992).
    • (1992) Int. J. Radiat. Biol. , vol.61 , pp. 315-321
    • Iliakis, G.1    Mehta, R.2    Jackson, M.3
  • 12
    • 0027512522 scopus 로고
    • Characterization of the DNA double strand break repair defect in scid mice
    • C. Chang, K. A. Biedermann, M. Mezzina and J. M. Brown, Characterization of the DNA double strand break repair defect in scid mice. Cancer Res. 53, 1244-1248 (1993).
    • (1993) Cancer Res. , vol.53 , pp. 1244-1248
    • Chang, C.1    Biedermann, K.A.2    Mezzina, M.3    Brown, J.M.4
  • 14
    • 0025980247 scopus 로고
    • Detection of DNA double strand breaks in synchronous cultures of CHO cells by means of asymmetric field inversion gel electrophoresis
    • G. Iliakis, L. Metzger, N. Denko and T. D. Stamato, Detection of DNA double strand breaks in synchronous cultures of CHO cells by means of asymmetric field inversion gel electrophoresis. Int. J. Radiat. Biol. 59, 321-341 (1991).
    • (1991) Int. J. Radiat. Biol. , vol.59 , pp. 321-341
    • Iliakis, G.1    Metzger, L.2    Denko, N.3    Stamato, T.D.4
  • 15
    • 0025739820 scopus 로고
    • Kinetics of DNA double strand breaks throughout the cell cycle as assayed by pulsed field gel electrophoresis in CHO cells
    • L. Metzger and G. Iliakis, Kinetics of DNA double strand breaks throughout the cell cycle as assayed by pulsed field gel electrophoresis in CHO cells. Int. J. Radiat. Biol. 59, 1325-1339 (1991).
    • (1991) Int. J. Radiat. Biol. , vol.59 , pp. 1325-1339
    • Metzger, L.1    Iliakis, G.2
  • 16
    • 0024582342 scopus 로고
    • An asymmetric field inversion gel electrophoresis method for the separation of large DNA molecules
    • N. Denko, A. Giaccia, B. Peters and T. D. Stamato, An asymmetric field inversion gel electrophoresis method for the separation of large DNA molecules. Anal. Biochem. 178, 172-176 (1989).
    • (1989) Anal. Biochem. , vol.178 , pp. 172-176
    • Denko, N.1    Giaccia, A.2    Peters, B.3    Stamato, T.D.4
  • 17
    • 0026027189 scopus 로고
    • Direct measurement by pulsed-field gel electrophoresis of induction and rejoining of X-ray-induced double-strand breaks in cultured mouse cells
    • S. Y. Ahn, B. Nevaldine and P. J. Hahn, Direct measurement by pulsed-field gel electrophoresis of induction and rejoining of X-ray-induced double-strand breaks in cultured mouse cells. Int. J. Radiat. Biol. 59, 661-675 (1991).
    • (1991) Int. J. Radiat. Biol. , vol.59 , pp. 661-675
    • Ahn, S.Y.1    Nevaldine, B.2    Hahn, P.J.3
  • 18
    • 0031030223 scopus 로고    scopus 로고
    • An assay for quantifying DNA double-strand break repair that is suitable for small numbers of unlabeled cells
    • J. A. Longo, B. Nevaldine, S. L. Longo, J. A. Winfield and P. J. Hahn, An assay for quantifying DNA double-strand break repair that is suitable for small numbers of unlabeled cells. Radiat. Res. 147, 35-40 (1997).
    • (1997) Radiat. Res. , vol.147 , pp. 35-40
    • Longo, J.A.1    Nevaldine, B.2    Longo, S.L.3    Winfield, J.A.4    Hahn, P.J.5
  • 20
    • 0021063154 scopus 로고
    • X-ray-sensitive mutants of Chinese hamster ovary cell line. Isolation and cross-sensitivity to other DNA-damaging agents
    • P. A. Jeggo and L. M. Kemp, X-ray-sensitive mutants of Chinese hamster ovary cell line. Isolation and cross-sensitivity to other DNA-damaging agents. Mutat. Res. 112, 313-327 (1983).
    • (1983) Mutat. Res. , vol.112 , pp. 313-327
    • Jeggo, P.A.1    Kemp, L.M.2
  • 21
    • 0024596693 scopus 로고
    • Biphasic survival curves for XRS radiosensitive cells: Subpopulations or transient expression of repair competence?
    • J. Denekamp, G. F. Whitmore and P. Jeggo, Biphasic survival curves for XRS radiosensitive cells: Subpopulations or transient expression of repair competence? Int. J. Radiat. Biol. 55, 605-617 (1989).
    • (1989) Int. J. Radiat. Biol. , vol.55 , pp. 605-617
    • Denekamp, J.1    Whitmore, G.F.2    Jeggo, P.3
  • 22
    • 0022994407 scopus 로고
    • Azacytidine-induced reactivation of a DNA repair gene in Chinese hamster ovary cells
    • P. A. Jeggo and R. Holliday, Azacytidine-induced reactivation of a DNA repair gene in Chinese hamster ovary cells. Mol. Cell. Biol. 6, 2944-2949 (1986).
    • (1986) Mol. Cell. Biol. , vol.6 , pp. 2944-2949
    • Jeggo, P.A.1    Holliday, R.2
  • 23
    • 0030926490 scopus 로고    scopus 로고
    • The scid defect results in much slower repair of DNA double-strand breaks but not high levels of residual breaks
    • B. Nevaldine, J. A. Longo and P. J. Hahn, The scid defect results in much slower repair of DNA double-strand breaks but not high levels of residual breaks. Radiat. Res. 147, 535-540 (1997).
    • (1997) Radiat. Res. , vol.147 , pp. 535-540
    • Nevaldine, B.1    Longo, J.A.2    Hahn, P.J.3
  • 25
    • 0026071588 scopus 로고
    • Scid mutation in mice confers hypersensitivity to ionizing radiation and a deficiency in DNA double-strand break repair
    • K. A. Biedermann, J. Sung, A. J. Giaccia, L. M. Tosto and J. M. Brown, scid mutation in mice confers hypersensitivity to ionizing radiation and a deficiency in DNA double-strand break repair. Proc. Natl. Acad. Sci. USA 88, 1394-1397 (1991).
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 1394-1397
    • Biedermann, K.A.1    Sung, J.2    Giaccia, A.J.3    Tosto, L.M.4    Brown, J.M.5
  • 27
    • 0025734394 scopus 로고
    • Fibroblasts from ataxia telangiectasia (AT) and AT heterozygotes show an enhanced level of residual DNA double-strand breaks after low dose-rate γ-irradiation as assayed by pulsed field gel electrophoresis
    • D. Blöcher, D. Sigut and M. A. Hannan, Fibroblasts from ataxia telangiectasia (AT) and AT heterozygotes show an enhanced level of residual DNA double-strand breaks after low dose-rate γ-irradiation as assayed by pulsed field gel electrophoresis. Int. J. Radiat. Biol. 60, 791-802 (1991).
    • (1991) Int. J. Radiat. Biol. , vol.60 , pp. 791-802
    • Blöcher, D.1    Sigut, D.2    Hannan, M.A.3
  • 28
    • 0028363754 scopus 로고
    • Absence of a Ku-like DNA end binding activity in the xrs double-strand DNA repair-deficient mutant
    • R. C. Getts and T. D. Stamato, Absence of a Ku-like DNA end binding activity in the xrs double-strand DNA repair-deficient mutant. J. Biol. Chem. 269, 15981-15984 (1994).
    • (1994) J. Biol. Chem. , vol.269 , pp. 15981-15984
    • Getts, R.C.1    Stamato, T.D.2
  • 29
    • 0028342645 scopus 로고
    • A DNA end-binding factor involved in double strand break repair and V(D)J recombination
    • W. K. Rathmell and G. A. Chu, A DNA end-binding factor involved in double strand break repair and V(D)J recombination. Mol. Cell. Biol. 14, 4741-4748 (1994).
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 4741-4748
    • Rathmell, W.K.1    Chu, G.A.2
  • 31
    • 0028897304 scopus 로고
    • DNA-dependent protein kinase activity is absent in xrs-6 cells: Implications for site-specific recombination and DNA double-strand break repair
    • N. J. Finnie, T. M. Gottlieb, T. Blunt, P. A. Jeggo and S. P. Jackson, DNA-dependent protein kinase activity is absent in xrs-6 cells: Implications for site-specific recombination and DNA double-strand break repair. Proc. Natl. Acad. Sci. USA 92, 320-324 (1995).
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 320-324
    • Finnie, N.J.1    Gottlieb, T.M.2    Blunt, T.3    Jeggo, P.A.4    Jackson, S.P.5
  • 33
    • 0028791446 scopus 로고
    • DNA double-strand break repair and V(D)J recombination: Involvement of DNA-PK
    • S. P. Jackson and P. A. Jeggo, DNA double-strand break repair and V(D)J recombination: involvement of DNA-PK. Trends Biochem. Sci. 20, 412-415 (1995).
    • (1995) Trends Biochem. Sci. , vol.20 , pp. 412-415
    • Jackson, S.P.1    Jeggo, P.A.2
  • 34
    • 0028855064 scopus 로고
    • DNA-dependent protein kinase: A potent inhibitor of transcription by RNA polymerase 1
    • A. Kuhn, T. M. Gottlieb, S. P. Jackson and I. Grummt, DNA-dependent protein kinase: A potent inhibitor of transcription by RNA polymerase 1. Genes Dev. 9, 193-203 (1995).
    • (1995) Genes Dev. , vol.9 , pp. 193-203
    • Kuhn, A.1    Gottlieb, T.M.2    Jackson, S.P.3    Grummt, I.4
  • 35
    • 0031059531 scopus 로고    scopus 로고
    • Tying loose ends: Roles of Ku and DNA-dependent protein kinase in the repair of double-strand breaks
    • M. R. Lieber, U. Grawunder, X. Wu and M. Yaneva, Tying loose ends: Roles of Ku and DNA-dependent protein kinase in the repair of double-strand breaks, Curr. Opin. Genet. Dev. 7, 99-104 (1997).
    • (1997) Curr. Opin. Genet. Dev. , vol.7 , pp. 99-104
    • Lieber, M.R.1    Grawunder, U.2    Wu, X.3    Yaneva, M.4
  • 37
    • 0030592555 scopus 로고    scopus 로고
    • The identification and characterization of mammalian proteins involved in the rejoining of DNA double-strand breaks in vitro
    • A. P. Johnson and M. P. Fairman, The identification and characterization of mammalian proteins involved in the rejoining of DNA double-strand breaks in vitro. Mutat. Res. 364, 103-116 (1996).
    • (1996) Mutat. Res. , vol.364 , pp. 103-116
    • Johnson, A.P.1    Fairman, M.P.2
  • 38
    • 0030471390 scopus 로고    scopus 로고
    • The joining of noncomplementary DNA double-strand breaks by mammalian extracts
    • R. M. Mason, J. Thacker and M. P. Fairman, The joining of noncomplementary DNA double-strand breaks by mammalian extracts. Nucleic Acids Res. 24, 4946-4953 (1996).
    • (1996) Nucleic Acids Res. , vol.24 , pp. 4946-4953
    • Mason, R.M.1    Thacker, J.2    Fairman, M.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.