Hematoprotection and enrichment of transduced cells in vivo after gene transfer of MGMTP140k into hematopoietic stem cells

Cancer Gene Therapy

Volumn 9, Issue 9, 2002, Pages 737-746

  Jansen, Michael ^a   Sorg, Ursula R ^a   Ragg, Susanne ^b   Flasshove, Michael ^a   Seeber, Siegfried ^a   Williams, David A ^b   Moritz, Thomas ^a  

^a UNIVERSITY HOSPITAL ESSEN   (Germany)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Chloroethylnitrosoureas; DNA repair; Gene therapy; O6 methylguanine DNA methyltransferase; Retroviral vectors; Temozolomide

Indexed keywords

6 O BENZYLGUANINE; ALKYLATING AGENT; CARMUSTINE; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; NIMUSTINE; TEMOZOLOMIDE; TRIAZINE DERIVATIVE; ENZYME INHIBITOR; FLUOROURACIL; GREEN FLUORESCENT PROTEIN; INTERLEUKIN 6; PHOTOPROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW; BONE MARROW TRANSPLANTATION; CANCER COMBINATION CHEMOTHERAPY; CANCER IMMUNOTHERAPY; CONTROLLED STUDY; DISEASE COURSE; FEMALE; GENE EXPRESSION; GENE OVEREXPRESSION; GENE TRANSFER; GRANULOCYTE; HEMATOPOIETIC STEM CELL; LYMPHOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SPLEEN; ANIMAL; B LYMPHOCYTE; C57BL MOUSE; COMPARATIVE STUDY; DNA REPAIR; DRUG EFFECT; DRUG RESISTANCE; ENZYMOLOGY; GENE VECTOR; GENETIC TRANSDUCTION; GENETICS; HUMAN; METABOLISM; PATHOLOGY; RETROVIRUS; T LYMPHOCYTE;

ANIMAL; ANTINEOPLASTIC AGENTS, ALKYLATING; B-LYMPHOCYTES; BONE MARROW TRANSPLANTATION; COMPARATIVE STUDY; DNA REPAIR; DRUG RESISTANCE, NEOPLASM; ENZYME INHIBITORS; FEMALE; FLUOROURACIL; GENETIC VECTORS; GRANULOCYTES; HEMATOPOIETIC STEM CELLS; HUMAN; INTERLEUKIN-6; LUMINESCENT PROTEINS; MICE; MICE, INBRED C57BL; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE; RETROVIRIDAE; SUPPORT, NON-U.S. GOV'T; T-LYMPHOCYTES; TRANSDUCTION, GENETIC; ANIMALS; GREEN FLUORESCENT PROTEINS; HUMANS;

EID: 0036708229     PISSN: 09291903     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cgt.7700490     Document Type: Article

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