Characterization of the P140K, PVP(138-140)MLK, and G156A O6- methylguanine-DNA methyltransferase mutants: Implications for drug resistance gene therapy

Human Gene Therapy

Volumn 10, Issue 17, 1999, Pages 2769-2778

  Davis, Brian M ^a   Roth, Justin C ^a   Liu, Lili ^a   Xu Welliver, Meng ^b   Pegg, Anthony E ^b   Gerson, Stanton L ^a  

^a UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

^b PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATING AGENT; CYCLOHEXIMIDE; DNA METHYLTRANSFERASE; GUANINE DERIVATIVE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; DRUG CYTOTOXICITY; ENZYME ACTIVITY; GENE MUTATION; GENE THERAPY; GENE TRANSFER; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN STABILITY; TUMOR RESISTANCE;

ANTINEOPLASTIC AGENTS; CARMUSTINE; CELL SURVIVAL; CLONING, MOLECULAR; DRUG INTERACTIONS; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; ENZYME STABILITY; GENE EXPRESSION; GENE THERAPY; GUANINE; HUMANS; K562 CELLS; MUTATION; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE; TRANSFECTION;

ANIMALIA;

EID: 0033589691     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/10430349950016500     Document Type: Article

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