-
1
-
-
0025195404
-
6-alkylguanine-DNA alkyltransferase: Regulation and importance in response to alkylating carcinogenic and therapeutic agents
-
6-alkylguanine-DNA alkyltransferase: regulation and importance in response to alkylating carcinogenic and therapeutic agents. Cancer Res., 50: 6119-6129, 1990.
-
(1990)
Cancer Res.
, vol.50
, pp. 6119-6129
-
-
Pegg, A.E.1
-
3
-
-
0020332947
-
6-methylguanine residues in E. coli DNA
-
6-methylguanine residues in E. coli DNA. Nature (Lond.), 296: 868-869, 1982.
-
(1982)
Nature (Lond.)
, vol.296
, pp. 868-869
-
-
Karran, P.1
Marinus, M.2
-
4
-
-
0022064910
-
6-Alkylguanine DNA alkyltransferase activity correlated with the therapeutic response of human rhabdomyosarcoma xenografts to 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea
-
6-Alkylguanine DNA alkyltransferase activity correlated with the therapeutic response of human rhabdomyosarcoma xenografts to 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea. Proc. Natl. Acad. Sci. USA, 82: 2985-2989, 1985.
-
(1985)
Proc. Natl. Acad. Sci. USA
, vol.82
, pp. 2985-2989
-
-
Brent, T.1
Houghton, P.2
Houghton, J.3
-
7
-
-
0022931463
-
6-alkylguanine DNA alkyltransferase activity based on cellular DNA content in human, rat and mouse tissues
-
6-alkylguanine DNA alkyltransferase activity based on cellular DNA content in human, rat and mouse tissues. Carcinogenesis (Lond.), 7: 745-749, 1986.
-
(1986)
Carcinogenesis (Lond.)
, vol.7
, pp. 745-749
-
-
Gerson, S.L.1
Trey, J.E.2
Miller, K.3
Berger, N.A.4
-
8
-
-
0030479125
-
Mismatch repair mutations override alkyltransferase in conferring resistance to temozolomide but not to 1,3-bis(2-chloroethyl)nitrosourea
-
Liu, L., Markowitz, S., and Gerson, S. L. Mismatch repair mutations override alkyltransferase in conferring resistance to temozolomide but not to 1,3-bis(2-chloroethyl)nitrosourea. Cancer Res., 56: 5375-5379, 1996.
-
(1996)
Cancer Res.
, vol.56
, pp. 5375-5379
-
-
Liu, L.1
Markowitz, S.2
Gerson, S.L.3
-
10
-
-
0027336891
-
6-alkylguanine DNA alkyltransferase correlates with potentiation of temozolomide and CCNU toxicity in human tumor cells
-
6-alkylguanine DNA alkyltransferase correlates with potentiation of temozolomide and CCNU toxicity in human tumor cells. Br. J. Cancer, 67: 1299-1302, 1993.
-
(1993)
Br. J. Cancer
, vol.67
, pp. 1299-1302
-
-
Baer, J.1
Freeman, A.2
Newlands, E.3
Watson, A.4
Rafferty, J.5
Margison, G.6
-
12
-
-
0027339636
-
6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) in a human colon cancer xenograft completely resistant to BCNU alone
-
6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) in a human colon cancer xenograft completely resistant to BCNU alone. Biochem. Pharmacol., 45: 483-491, 1993.
-
(1993)
Biochem. Pharmacol.
, vol.45
, pp. 483-491
-
-
Gerson, S.1
Zborowska, E.2
Norton, K.3
Gordon, N.4
Willson, J.5
-
13
-
-
0027337683
-
6-benzylguanine on the sensitivity of human colon tumor xenografts to 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU)
-
6-benzylguanine on the sensitivity of human colon tumor xenografts to 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU). Biochem. Pharmacol., 46: 285-290, 1993.
-
(1993)
Biochem. Pharmacol.
, vol.46
, pp. 285-290
-
-
Dolan, M.E.1
Pegg, A.E.2
Moschel, R.C.3
Grindey, G.B.4
-
14
-
-
0026610238
-
6 - Benzylguanine on the sensitivity of human tumor xenografts to 1,3-bis(2-chloroethyl)-1-nitrosourea and on DNA interstrand crosslink formation
-
6 - benzylguanine on the sensitivity of human tumor xenografts to 1,3-bis(2-chloroethyl)-1-nitrosourea and on DNA interstrand crosslink formation. Cancer Res., 52: 1171-1175, 1992.
-
(1992)
Cancer Res.
, vol.52
, pp. 1171-1175
-
-
Mitchell, R.1
Moschel, R.2
Dolan, M.3
-
15
-
-
0029011186
-
Activity of temozolomide in the treatment of central nervous system tumor xenografts
-
Friedman, H. S., Dolan, M. E., Pegg, A. E., Marcelli, S., Keir, S., Catino, J. J., Bigner, D. D., and Schold, S., Jr. Activity of temozolomide in the treatment of central nervous system tumor xenografts. Cancer Res., 55: 2853-2857, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 2853-2857
-
-
Friedman, H.S.1
Dolan, M.E.2
Pegg, A.E.3
Marcelli, S.4
Keir, S.5
Catino, J.J.6
Bigner, D.D.7
Schold Jr., S.8
-
17
-
-
0030445950
-
6-benzylguanine plus 1,3-bis(2-chloroethyl)-1-nitrosourea
-
6-benzylguanine plus 1,3-bis(2-chloroethyl)-1-nitrosourea. Proc. Natl. Acad. Sci. USA, 93: 14088-14093, 1996.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 14088-14093
-
-
Reese, J.1
Koç, O.2
Lee, K.3
Liu, L.4
Allay, J.5
Phillips, W.6
Gerson, S.7
-
19
-
-
0030613767
-
6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea
-
6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea. Cancer Res., 57: 5093-5099, 1997.
-
(1997)
Cancer Res.
, vol.57
, pp. 5093-5099
-
-
Davis, B.1
Reese, J.2
Koç, O.3
Lee, K.4
Schupp, J.5
Gerson, S.6
-
20
-
-
0016778170
-
Reaction of 1,3-bis(2-chloroethyl)-1-nitrosourea with synthetic polynucleotides
-
Ludlum, D., Kramer, B., Wang, J., and Fenselau, C. Reaction of 1,3-bis(2-chloroethyl)-1-nitrosourea with synthetic polynucleotides. Biochemistry, 14: 5480-5485, 1975.
-
(1975)
Biochemistry
, vol.14
, pp. 5480-5485
-
-
Ludlum, D.1
Kramer, B.2
Wang, J.3
Fenselau, C.4
-
21
-
-
0019131692
-
Human tumor cell strains defective in the repair of alkylation damage
-
Day, R., III, Ziolkowski, C., Scudiero, D., Meyer, S., and Mattern, M. Human tumor cell strains defective in the repair of alkylation damage. Carcinogenesis (Lond.), 1: 21-32, 1980.
-
(1980)
Carcinogenesis (Lond.)
, vol.1
, pp. 21-32
-
-
Day III, R.1
Ziolkowski, C.2
Scudiero, D.3
Meyer, S.4
Mattern, M.5
-
22
-
-
0030993717
-
Temozolomide: A review of its discovery, chemical properties, preclinical development and clinical trials
-
Newlands, E., Stevens, M., Wedge, S., Wheelhouse, R., and Brock, C. Temozolomide: a review of its discovery, chemical properties, preclinical development and clinical trials. Cancer Treat. Rev., 23: 35-61, 1997.
-
(1997)
Cancer Treat. Rev.
, vol.23
, pp. 35-61
-
-
Newlands, E.1
Stevens, M.2
Wedge, S.3
Wheelhouse, R.4
Brock, C.5
-
23
-
-
0022931463
-
6-alkylguanine-DNA alkyltransferase activity based on cellular DNA content in human, rat and mouse tissues
-
6-alkylguanine-DNA alkyltransferase activity based on cellular DNA content in human, rat and mouse tissues. Carcinogenesis (Lond.), 7: 745-749, 1986.
-
(1986)
Carcinogenesis (Lond.)
, vol.7
, pp. 745-749
-
-
Gerson, S.L.1
Trey, J.E.2
Miller, K.3
Berger, N.A.4
-
24
-
-
0031914043
-
Autologous CD34+ cells transplantation for patients with advanced lymphoma: Effects of overnight storage on peripheral blood progenitor cell enrichment and engraftment
-
Koç, O., Gerson, S., Phillips, G., Cooper, B., Kutteh, L., Van Zant, G., Reece, D., Fox, R., Schupp, J., Tainer, N., and Lazarus, H. Autologous CD34+ cells transplantation for patients with advanced lymphoma: effects of overnight storage on peripheral blood progenitor cell enrichment and engraftment. Bone Marrow Transplant., 227: 337-343, 1998.
-
(1998)
Bone Marrow Transplant.
, vol.227
, pp. 337-343
-
-
Koç, O.1
Gerson, S.2
Phillips, G.3
Cooper, B.4
Kutteh, L.5
Van Zant, G.6
Reece, D.7
Fox, R.8
Schupp, J.9
Tainer, N.10
Lazarus, H.11
-
25
-
-
33646293893
-
6-benzylguanine and BCNU and remain active after high dose BG
-
6-benzylguanine and BCNU and remain active after high dose BG. Blood, 92: 466A, 1998.
-
(1998)
Blood
, vol.92
-
-
Davis, B.1
Roth, J.2
Liu, L.3
Friebert, S.4
Schupp, J.5
Neumann, A.6
Pegg, A.7
Gerson, S.8
-
26
-
-
0022272291
-
6-Alkylguanine DNA alkyltransferase activity in human myeloid cells
-
6-Alkylguanine DNA alkyltransferase activity in human myeloid cells. J. Clin. Investig., 76: 2106-2114, 1985.
-
(1985)
J. Clin. Investig.
, vol.76
, pp. 2106-2114
-
-
Gerson, S.1
Miller, K.2
Berger, N.3
-
27
-
-
0026637623
-
Selection of drug-resistant bone marrow cells in vivo after retroviral transfer of human MDR1
-
Sorrentino, B., Brandt, S., Bodine, D., Gottesman, M., Pastan, I., Cline, A., and Nienhuis, A. Selection of drug-resistant bone marrow cells in vivo after retroviral transfer of human MDR1. Science (Washington DC), 257: 99-103, 1992.
-
(1992)
Science (Washington DC)
, vol.257
, pp. 99-103
-
-
Sorrentino, B.1
Brandt, S.2
Bodine, D.3
Gottesman, M.4
Pastan, I.5
Cline, A.6
Nienhuis, A.7
-
28
-
-
0028403214
-
Serial transplantation shows that early hematopoietic precursor cells are transduced by MDR-1 retroviral vector in a mouse gene therapy model
-
Hanania, E. G., and Deisseroth, A. B. Serial transplantation shows that early hematopoietic precursor cells are transduced by MDR-1 retroviral vector in a mouse gene therapy model. Cancer Gene Then, 1: 21-25, 1994.
-
(1994)
Cancer Gene Then
, vol.1
, pp. 21-25
-
-
Hanania, E.G.1
Deisseroth, A.B.2
-
29
-
-
0028340408
-
Development of a retroviral construct containing a human mutated dihydrofolate reductase cDNA for hematopoietic stem cell transduction
-
Li, M-X., Banerjee, D., Zhao, S., Schweitzer, B. I., Mineishi, S., Gilboa, E., and Bertino, J. R. Development of a retroviral construct containing a human mutated dihydrofolate reductase cDNA for hematopoietic stem cell transduction. Blood, 83: 3403-3408, 1994.
-
(1994)
Blood
, vol.83
, pp. 3403-3408
-
-
Li, M.-X.1
Banerjee, D.2
Zhao, S.3
Schweitzer, B.I.4
Mineishi, S.5
Gilboa, E.6
Bertino, J.R.7
-
30
-
-
0030061083
-
Increasing DNA repair methyltransferase levels via bone marrow stem cell transduction rescues mice from the toxic effects of 1,3-bis(2-chloroethyl)-1-nitrosourea, a chemotherapeutic alkylating agent
-
Maze, R., Carney, J. P., Kelley, M. R., Glassner, B. J., Williams, D. A., and Samson, L. Increasing DNA repair methyltransferase levels via bone marrow stem cell transduction rescues mice from the toxic effects of 1,3-bis(2-chloroethyl)-1-nitrosourea, a chemotherapeutic alkylating agent. Proc. Natl. Acad. Sci. USA, 93: 206-210, 1996.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 206-210
-
-
Maze, R.1
Carney, J.P.2
Kelley, M.R.3
Glassner, B.J.4
Williams, D.A.5
Samson, L.6
-
31
-
-
0029016285
-
Retrovirus-mediated expression of a DNA repair protein in bone marrow protects hematopoietic cells from nitrosourea-induced toxicity in vitro and in vivo
-
Moritz, T., Mackay, W., Glassner, B. J., Williams, D. A., and Samson, L. Retrovirus-mediated expression of a DNA repair protein in bone marrow protects hematopoietic cells from nitrosourea-induced toxicity in vitro and in vivo. Cancer Res., 55: 2608-2614, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 2608-2614
-
-
Moritz, T.1
Mackay, W.2
Glassner, B.J.3
Williams, D.A.4
Samson, L.5
-
32
-
-
33646296591
-
6-benzylguanine plus BCNU
-
in press
-
6-benzylguanine plus BCNU. J. Clin. Oncol., in press, 1998.
-
(1998)
J. Clin. Oncol.
-
-
Dolan, M.1
-
33
-
-
0026468376
-
6-methylguanine DNA methyltransferase and chloroethylnitrosourea-treated DNA
-
6-methylguanine DNA methyltransferase and chloroethylnitrosourea-treated DNA. Cancer Res., 52: 6052-6058, 1992.
-
(1992)
Cancer Res.
, vol.52
, pp. 6052-6058
-
-
Gonzaga, P.1
Potter, P.2
Niu, T.3
Yu, D.4
Ludlum, D.5
Rafferty, J.6
Margison, G.7
Brent, T.8
-
34
-
-
0030614974
-
6-Benzylguanine potentiates in in vivo toxicity and clastogenicity of temozolomide and BCNU in mouse bone marrow
-
6-Benzylguanine potentiates in in vivo toxicity and clastogenicity of temozolomide and BCNU in mouse bone marrow. Blood, 89: 1566-1573, 1997.
-
(1997)
Blood
, vol.89
, pp. 1566-1573
-
-
Chinnasamy, N.1
Rafferty, J.2
Hickson, I.3
Ashby, J.4
Tinwell, H.5
Margison, G.6
Dexter, M.7
Fairbairn, L.8
-
35
-
-
0028985112
-
6-Benzylguanine increases the sensitivity of human primary bone marrow cells to the cytotoxic effects of temozolomide
-
6-Benzylguanine increases the sensitivity of human primary bone marrow cells to the cytotoxic effects of temozolomide. Exp. Hematol., 23: 112-116, 1995.
-
(1995)
Exp. Hematol.
, vol.23
, pp. 112-116
-
-
Fairbairn, L.1
Watson, A.2
Rafferty, J.3
Elder, R.4
Margison, G.5
-
36
-
-
33646315088
-
6-benzylguanine and BCNU and allows intensive therapy of BCNU resistant xenografts in mice
-
6-benzylguanine and BCNU and allows intensive therapy of BCNU resistant xenografts in mice. Blood, 90: 243a, 1997.
-
(1997)
Blood
, vol.90
-
-
Koç, O.1
Davis, B.2
Reese, J.3
Liu, L.4
Gerson, S.5
|