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Volumn 185, Issue , 2002, Pages 236-265

Human retroviruses after 20 years: A perspective from the past and prospects for their future control

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CELL DNA; VIRUS VACCINE;

EID: 0036630405     PISSN: 01052896     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-065X.2002.18520.x     Document Type: Review
Times cited : (58)

References (258)
  • 4
    • 0014964654 scopus 로고
    • RNA-dependent DNA polymerase in virions of RNA tumour viruses
    • (1970) Nature , vol.226 , pp. 1209-1211
    • Baltimore, D.1
  • 8
    • 0015898835 scopus 로고
    • Purification, characterization, and comparison of the DNA polymerases from two primate RNA tumor viruses
    • (1973) J Virol , vol.12 , pp. 431-439
    • Abrell, J.W.1    Gallo, R.C.2
  • 12
  • 14
    • 0014644555 scopus 로고
    • Studies on colony formation in vitro by mouse bone marrow cells. I. Continuous cluster formation and relation of clusters to colonies
    • (1969) J Cell Physiol , vol.74 , pp. 323-332
    • Metcalf, D.1
  • 19
    • 0011791617 scopus 로고
    • Purification and some characteristics of human T-cell growth factor from phytohemagglutinin-stimulated lymphocyte-conditioned media
    • (1980) Proc Natl Acad Sci USA , vol.77 , pp. 6134-6138
    • Mier, J.W.1    Gallo, R.2
  • 28
    • 0019781211 scopus 로고
    • Adult T-cell leukemia: Antigen in an ATL cell line and detection of antibodies of die antigen in human sera
    • (1981) Proc Natl Acad Sci USA , vol.78 , pp. 6476-6480
    • Hinuma, Y.1
  • 29
    • 0019937135 scopus 로고
    • The virus of Japanese adult T-cell leukaemia is a member of the human T-cell leukaemia virus group
    • (1982) Nature , vol.300 , pp. 63-66
    • Popovic, M.1
  • 30
    • 0020059663 scopus 로고
    • Adult T-cell lymphoma-leukaemia in blacks from the West Indies
    • (1982) Lancet , vol.1 , pp. 639-642
    • Catovsky, D.1
  • 32
    • 0019996381 scopus 로고
    • The human type-C retrovirus, HTLV, in blacks from the Caribbean region, and relationship to adult T-cell leukemia/lymphoma
    • (1982) Int J Cancer , vol.30 , pp. 257-264
    • Blattner, W.1
  • 34
    • 0019907946 scopus 로고
    • A new subtype of human T-cell leukemia virus (HTLV-II) associated with a T-cell variant of hairy cell leukemia
    • (1982) Science , vol.218 , pp. 571-573
    • Kalyanaraman, V.S.1
  • 35
    • 0021995980 scopus 로고
    • Antibodies of human T-lymphotropic virus type-I in patients with tropical spastic paraparesis
    • (1985) Lancet , vol.2 , pp. 407-410
    • Gessain, A.1
  • 36
    • 0023099872 scopus 로고
    • Chronic progressive myelopathy associated with elevated antibodies of human T-lymphotropic virus type I and adult T-cell leukemia like cells
    • (1987) Ann Neurol , vol.21 , pp. 117-122
    • Osame, M.1
  • 37
    • 0019802745 scopus 로고
    • Type C virus particles in a cord T-cell line derived by co-cultivatingnormal human cord leukocytes and human leukaemic T cells
    • (1981) Nature , vol.294 , pp. 770-771
    • Miyoshi, I.1
  • 40
    • 0035064503 scopus 로고    scopus 로고
    • Multiple viral strategies of HTLV-1 for dysregulation of cell growth control
    • (2001) Annu Rev Immunol , vol.19 , pp. 475-496
    • Yoshida, M.1
  • 45
    • 0026760622 scopus 로고
    • Transcriptional activator Tax of HTLV-1 binds to the NF-kappa B precursor p105
    • (1992) Oncogene , vol.7 , pp. 1737-1742
    • Hirai, H.1
  • 46
    • 0026725132 scopus 로고
    • Human T-cell lymphotropic virus type I (HTLV-1) transcriptional activator, tax, enhances CREB binding to HTLV-I 21-based-pair repeats by protein-protein interaction
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 7070-7074
    • Zhao, L.J.1    Giam, C.Z.2
  • 49
    • 0034693058 scopus 로고    scopus 로고
    • Clastogenic effect of the human T-cell leukemia virus type I tax oncoprotein correlates with unstablized DNA breaks
    • (2000) J Biol Chem , vol.275 , pp. 32906-32910
    • Majone, F.1    Jeang, K.T.2
  • 50
    • 0034511443 scopus 로고    scopus 로고
    • Immunopathogenesis of HTLV-I-associated myelopathy/tropical spastic paraparesis
    • (2000) Ann Med , vol.32 , pp. 600-607
    • Nakamura, T.1
  • 52
    • 0033945533 scopus 로고    scopus 로고
    • Human T-lymphotropic virus type-1 infected T lymphocytes impair catabolism and uptake of glutamate by astrocytes via tax-1 and tumor necrosis factor alpha
    • (2000) J Virol , vol.74 , pp. 6433-6441
    • Zymucha, R.1
  • 62
    • 0020534136 scopus 로고
    • Proviral DNA of a retrovirus, human T-cell leukemia virus, in two patients with AIDS
    • (1983) Science , vol.220 , pp. 862-865
    • Gelmann, E.P.1
  • 63
    • 0020596551 scopus 로고
    • Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome AIDS
    • (1983) Science , vol.220 , pp. 868-871
    • Barre-Sinoussi, F.1
  • 64
    • 0002992613 scopus 로고
    • A new human T-lymphotropic retrovirus. Characterization and possible role in lymphadenopathy and immune deficiency syndromes
    • Gallo RC, Essex ME, Gross L, eds. New York: Cold Spring Harbor Laboratory
    • (1984) Human T-cell leukemia/lymphoma viruses , pp. 363-379
    • Montagnier, L.1
  • 65
    • 0021261510 scopus 로고
    • Frequent detection and isolation of cytopathic retroviruses (HTLV-III) from patients with AIDS and at risk for AIDS
    • (1984) Science , vol.224 , pp. 500-503
    • Gallo, R.1
  • 69
    • 0021267497 scopus 로고
    • Seroepidemiological studies of human T-lymphotropic type III in acquired immunodeficiency syndrome
    • (1984) Lancet , vol.1 , pp. 1438-1440
    • Safai, B.1
  • 71
    • 0001707601 scopus 로고
    • 3′-Azido-3′-deoxythymidine (BW A509U): An Antiviral agent that inhibits the infectivity and cytopathic effect of human T-lymphotropic virus type III/lymphadenopathy-associated virus in vitro
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 7095-7100
    • Mitsuya, H.1
  • 72
    • 0021912920 scopus 로고
    • Complete nucleotide sequence of the AIDS virus, HTLV-III
    • (1985) Nature , vol.313 , pp. 277-284
    • Ratner, L.1
  • 74
    • 0021914933 scopus 로고
    • Nucelotide sequence and expression of an AIDS-associated retrovirus (ARV-2)
    • (1985) Science , vol.227 , pp. 484-492
    • Sanchez-Pescador, R.1
  • 75
    • 0022459886 scopus 로고
    • Identification and characterization of conserved and variable regions in the envelope gene of HTLV-III/LAV, the retrovirus of AIDS
    • (1986) Cell , vol.45 , pp. 637-648
    • Starcich, B.R.1
  • 82
    • 0022003610 scopus 로고
    • Trans-acting transcriptional regulation of human T-cell leukemia virus type III long terminal repeat
    • (1985) Science , vol.227 , pp. 171-173
    • Sodroski, J.1
  • 85
    • 0021806430 scopus 로고
    • Genomic diversity of human T-lymphotropic virus type III (HTLV-III)
    • (1985) Science , vol.229 , pp. 759-762
    • Wong-Staal, F.1
  • 86
    • 0021245303 scopus 로고
    • Low prevalence in the UK of HTLV-I and HTLV-II infection in subjects with AIDS, with extended lymphadenopathy, and at risk of AIDS
    • (1984) Lancet , vol.2 , pp. 125-128
    • Tedder, R.S.1
  • 87
    • 0021720872 scopus 로고
    • T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV
    • (1984) Nature , vol.312 , pp. 767-768
    • Klatzmann, D.1
  • 88
    • 0022001670 scopus 로고
    • HTLV-III infection in brains of children and adults with AIDS encephalopathy
    • (1985) Science , vol.227 , pp. 177-182
    • Shaw, G.M.1
  • 89
    • 0021222323 scopus 로고
    • HTVL-III in cells cultured from semen of two patients with AIDS
    • (1984) Science , vol.226 , pp. 449-451
    • Zagury, D.1
  • 90
    • 0021172216 scopus 로고
    • HTLV-III in the semen and blood of a healthy homosexual man
    • (1984) Science , vol.226 , pp. 451-453
    • Ho, D.D.1
  • 92
    • 0021994898 scopus 로고
    • Isolation of T-cell tropic HTLV-III-like retrovirus from macaques
    • (1985) Science , vol.228 , pp. 1201-1204
    • Daniel, M.D.1
  • 94
    • 0026024146 scopus 로고
    • Sequence analysis of original HIV-1
    • (1991) Nature , vol.349 , pp. 745-746
    • Guo, H.-G.1
  • 95
    • 0025804107 scopus 로고
    • LAV revisited: Origins of the early HIV-1 isolates from Institut Pasteur
    • (1991) Science , vol.252 , pp. 961-965
    • Wain-Hobson, S.1
  • 96
    • 0021806430 scopus 로고
    • Genomic diversity of human T-lymphotropic virus type III (HTLV-III)
    • (1985) Science , vol.229 , pp. 759-762
    • Wong-Staal, F.1
  • 97
    • 0037551476 scopus 로고
    • Genomic diversity of the acquired immune deficiency syndrome virus HTLV-III. Different viruses exhibit greatest divergence in their envelope genes
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 4813-4817
    • Hahn, B.F.1
  • 101
    • 0028301838 scopus 로고
    • Cellular latency in human immunodeficiency virus-infected individuals with high CD4 levels can be detected by the presence of promoter- proximal transcripts
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3862-3866
    • Adams, M.1
  • 102
    • 0030913366 scopus 로고    scopus 로고
    • Quanitification of latent tissue reservoirs and total body viral load in HIV-1 infection
    • (1997) Nature , vol.387 , pp. 183-187
    • Chun, T.W.1
  • 103
    • 0030659177 scopus 로고    scopus 로고
    • Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 13193-13197
    • Chun, T.W.1
  • 105
    • 0035794637 scopus 로고    scopus 로고
    • The site of HIV-1 integration in the human genome determines basal transcriptional activity and response to Tat transactivation
    • (2001) EMBO J , vol.20 , pp. 1726-1738
    • Jordan, A.1    Defechereux, P.2    Verdin, E.3
  • 107
    • 0026011173 scopus 로고
    • In vitro infection of natural killer cells with different human immunodeficiency virus type 1 isolates
    • (1991) J Virol , vol.65 , pp. 1812-1822
    • Chehimi, J.1
  • 110
    • 0030070991 scopus 로고    scopus 로고
    • Prognosis in HIV-1 infection predicted by the quantity of virus in plasma
    • (1996) Science , vol.272 , pp. 1167-1170
    • Mellors, J.W.1
  • 111
    • 0034030697 scopus 로고    scopus 로고
    • Natural history of HIV-1 viremia after seroconversion and proximal to AIDS in a large cohort
    • (2002) J Infect Dis , vol.181 , pp. 872-880
    • Lyles, R.H.1
  • 112
    • 0029683640 scopus 로고    scopus 로고
    • Serum HIV-1 RNA levels and time to development of AIDS in the multicenter hemophilia cohort study
    • (1996) JAMA , vol.276 , pp. 105-110
    • O'Brien, T.R.1
  • 115
    • 0030722896 scopus 로고    scopus 로고
    • Inhibition of HIV-1 infection by the α-chemokine MDC
    • (1997) Science , vol.278 , pp. 695-698
    • Pal, R.1
  • 116
    • 0033647217 scopus 로고    scopus 로고
    • The effect of genetic variation in chemokines and their receptors on HIV transmission and progression to AIDS
    • (2000) Immunol Rev , vol.177 , pp. 99-111
    • O'Brien, S.J.1    Moore, J.2
  • 118
    • 0032565314 scopus 로고    scopus 로고
    • +) lymphocytes from exposed-uninfected individuals: Association with long expression of CCR5 and high production of beta-chemokines
    • (1998) Virology , vol.244 , pp. 66-73
    • Paxton, W.A.1
  • 120
  • 122
    • 0022629524 scopus 로고
    • Long-term cultures of HTLV-III infected T cells. A model of cytopathology of T-cell depletion in AIDS
    • (1986) Science , vol.231 , pp. 850-853
    • Zagury, D.1
  • 124
    • 0035423912 scopus 로고    scopus 로고
    • Immune activation correlates better than HIV plasma viral load with CD4 T-cell decline during HIV infection
    • (2001) J Acquir Immune Defic Syndr , vol.27 , pp. 389-397
    • Leng, Q.1
  • 127
    • 0034976871 scopus 로고    scopus 로고
    • Increased CCR5 and CXCR4 expression in Ethiopians in Israel: Environmental and constitutive factors
    • (2001) Clin Immun , vol.100 , pp. 107-117
    • Kalinkovich, A.1
  • 128
    • 10544241554 scopus 로고    scopus 로고
    • Quantitative image analysis of HIV-1 infection in lymphoid tissue
    • (1996) Science , vol.274 , pp. 985-989
    • Haase, A.T.1
  • 129
    • 0034598905 scopus 로고    scopus 로고
    • DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells
    • (2000) Cell , vol.100 , pp. 587-597
    • Geijtenbeek, T.B.1
  • 130
    • 0034284793 scopus 로고    scopus 로고
    • Whole body positron emission tomography imaging of activated lymphoid tissues during acute SHIV89.6PD infection in rhesus macaques
    • (2000) Virology , vol.274 , pp. 255-261
    • Wallace, M.1
  • 133
    • 0026543981 scopus 로고
    • Viral DNA and mRNA expression correlate with the stage of human immunodeficiency virus (HIV) type 1 infection in humans: Evidence for viral replication in all stages of HIV disease
    • (1992) J Virol , vol.66 , pp. 310-316
    • Michael, N.L.1    Vahey, M.2    Burke, D.3    Redfield, R.R.4
  • 137
    • 25544469547 scopus 로고
    • Evidence of a process of death of lymphocytes by apoptosis in patients infected with HIV
    • (1993) CR Acad Sci Paris , vol.3 SERIES 312 , pp. 529-537
    • Gougeon, M.L.1
  • 141
    • 0021265316 scopus 로고
    • Lymphadenopathy associated virus. Infection of a blood donor-recipient pair with Acquired Immunodeficiency Syndrome
    • (1984) Science , vol.225 , pp. 69-73
    • Feorino, P.M.1
  • 143
    • 0028912254 scopus 로고
    • Aopotosis occurs predominantly in bystander cells and not in productively infected cells of HIV and SIV infected lymph nodes
    • (1995) Nat Med , vol.1 , pp. 129-134
    • Finkel, T.H.1
  • 145
    • 0031019006 scopus 로고    scopus 로고
    • + T lymphocytes from HIV-infected individuals is mediated by FasL and Tumor Necrosis Factor
    • (1997) J Exp Med , vol.1 , pp. 55-64
    • Badley, A.D.1
  • 147
    • 0032103109 scopus 로고    scopus 로고
    • The expression of Fas ligand by macrophages and its upregulation by Human Immunodeficiency Virus infection
    • (1998) J Clin Invest , vol.101 , pp. 2394-2405
    • Dockrell, D.H.1
  • 149
    • 0025323929 scopus 로고
    • HIV infection of human bone marrow stromal fibroblasts
    • (1990) Blood , vol.76 , pp. 317-322
    • Scadden, D.T.1
  • 152
    • 0026633303 scopus 로고
    • + bone marrow cells are infected with HIV in a subset of seropositive individuals
    • (1992) J Virol , vol.149 , pp. 689-697
    • Stanley, S.K.1
  • 154
    • 0028956139 scopus 로고
    • In vitro human immunodeficiency virus-1 infection purified hematopoietic progenitors single-cell culture
    • (1995) Blood , vol.85 , pp. 1181-1187
    • Chelucci, H.J.1
  • 155
  • 157
    • 0035575775 scopus 로고    scopus 로고
    • Evidence for increased T cell turnover and decreased thymic output in HIV infection
    • (2001) J Immunol , vol.167 , pp. 6663-6668
    • Douek, D.1
  • 161
    • 0033966504 scopus 로고    scopus 로고
    • Persistence of episomal HIV-1 infection intermediates in patients on highly active anti-retroviral therapy
    • (2002) Nat Med , vol.1 , pp. 76-81
    • Sharkey, M.E.1
  • 163
    • 0023449237 scopus 로고
    • Inhibition of human immunodeficiency virus syncytium formation and virus replication castanospermine
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 8120-8124
    • Walker, B.D.1
  • 166
    • 0032555938 scopus 로고    scopus 로고
    • + T-lymphocyte depletion in simian-human immunodeficiency virus-infected macaques
    • (1998) J Exp Med , vol.188 , pp. 1159-1171
    • Karlsson, G.1
  • 167
    • 0035012787 scopus 로고    scopus 로고
    • + T-cell depletion in macaques infected by a simian-human immunodeficiency virus
    • (2001) J Virol , vol.75 , pp. 5645-5655
    • Etemad-Moghadam, B.1
  • 168
    • 0029029058 scopus 로고
    • Sensitization of T-cells to CD95 mediated apoptosis by HIV-1 tat and gp120
    • (1995) Nature , vol.375 , pp. 497-500
    • Westerndorp, M.O.1
  • 169
  • 173
    • 0035798131 scopus 로고    scopus 로고
    • Dynamic disruptions in nuclear envelope architecture and integrity induced by HIV-1 Vpr
    • (2001) Science , vol.294 , pp. 1105-1108
    • De Noronha, C.M.C.1
  • 177
    • 0032546817 scopus 로고    scopus 로고
    • HIV-1 regulatory/accessory genes: Keys to unraveling viral and host cell biology
    • (1998) Science , vol.280 , pp. 1880-1884
    • Emerman, M.1    Malim, M.H.2
  • 178
    • 0032577444 scopus 로고    scopus 로고
    • HIV-1 auxiliary proteins: Making connections in a dying cell
    • (1998) Cell , vol.93 , pp. 685-692
    • Cullen, B.R.1
  • 179
    • 0003124066 scopus 로고    scopus 로고
    • HIV-1 Vpr increases viral expression by manipulation of the cell cycle: A mechanism for selection of Vpr in vivo
    • (1998) Nature Med , vol.4 , pp. 65-71
    • Goh, W.C.1
  • 180
    • 0029165291 scopus 로고
    • The human immunodeficiency virus type 1 vpr gene arrests infected T cells in the G2+ M phase of the cell cycle
    • (1995) J Virol , vol.69 , pp. 6304-6313
    • Jowett, J.B.1
  • 183
    • 0025052645 scopus 로고
    • Reinfection results in accumulation of unintegrated viral DNA in cytopathic and persistent human immunodeficiency virus type 1 infection of CEM cells
    • (1990) J Exp Med , vol.172 , pp. 1035-1042
    • Pauza, C.D.1    Galindo, J.2    Richamn, D.D.3
  • 184
    • 0034854361 scopus 로고    scopus 로고
    • An examination of signs of disease progression in survivors of the Sydney blood bank cohort
    • (2001) J Clin Virol , vol.22 , pp. 263-270
    • Birch, M.R.1
  • 185
    • 0034795885 scopus 로고    scopus 로고
    • +) T-cell depletion in human lymphoid tissue ex vivo
    • (2001) J Virol , vol.75 , pp. 10113-10117
    • Glushakova, S.1
  • 186
  • 188
    • 0035128420 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 nef selectively associates with a catalytically active subpopulation of p21-activated kinase2 (PAK2) independently of PAK2 binding to NcK or α-PIX
    • (2001) J Virol , vol.75 , pp. 2154-2160
    • Renkema, G.H.1    Manninen, A.2    Saksela, K.3
  • 189
    • 0030744349 scopus 로고    scopus 로고
    • Evasion of cytotoxic T lymphocyte (CTL) responses by Nef-dependent induction of Fas Ligand (CD95L) expression of Simian Immunodeficiency Virus-infected cells
    • (1997) J Exp Med , vol.186 , pp. 7-16
    • Xu, X.-N.1
  • 190
    • 0033519235 scopus 로고    scopus 로고
    • Induction of Fas Ligand expression by HIV involved the interaction of Nef with the T cell receptor ζ chain
    • (1999) J Exp Med , vol.189 , pp. 1489-1496
    • Xu, X.-N.1
  • 191
    • 0033587718 scopus 로고    scopus 로고
    • Tat as one key to HIV-induced immune pathogenesis and Tat toxoid as an important component of a vaccine (Perspective)
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 8324-8326
    • Gallo, R.C.1
  • 195
    • 0028223435 scopus 로고
    • Human immunodeficiency virus 1 Tat binds to dipeptidyl aminopeptidase IV (CD26): A possible mechanism for Tat's immunosuppressive activity
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 6594
    • Gutheil, W.G.1
  • 197
    • 0032504018 scopus 로고    scopus 로고
    • HIV type 1 Tat protein inhibits interleukin 12 production by human peripheral blood mononuclear cells
    • (1998) AIDS Res Hum Retroviruses , vol.14 , pp. 845
    • Ito, M.1
  • 200
    • 0033568286 scopus 로고    scopus 로고
    • Recombinant INF-α (2b) increases the expression of apoptosis receptor CD95 and chemokine receptors CCR1 and CCR3 in monocytoid cells
    • (1999) J Immunol , vol.163 , pp. 3169-3175
    • Zella, D.1
  • 202
    • 13144283615 scopus 로고    scopus 로고
    • Interferon α and Tat involvement in the immunosuppression of uninfected cells and C-C chemokine decline in AIDS
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 3851-3856
    • Zagury, D.1
  • 205
    • 0025344596 scopus 로고
    • Tat protein of HIV-1 stimulates growth of cells derived from Kaposi sarcoma lesions of AIDS patients
    • (1990) Nature , vol.345 , pp. 84-86
    • Ensoli, B.1
  • 209
    • 0027201115 scopus 로고
    • +) cells purified from bone marrow of AIDS patients are committed to apoptotic cell death in culture
    • (1993) AIDS , vol.7 , pp. 1049
    • Re, M.C.1
  • 210
  • 212
    • 0035864943 scopus 로고    scopus 로고
    • Virologic and immunologic consequences of discontinuing combination antiretroviral-drug therapy in HIV-infected patients with detectable viremia
    • (2001) N Engl J Med , vol.344 , pp. 472-480
    • Deeks, S.G.1
  • 214
    • 0034948377 scopus 로고    scopus 로고
    • Impaired replication of protease inhibitor-resistant HIV-1 in human thymus
    • (2001) Nat Med , vol.7 , pp. 712-718
    • Stoddart, C.A.1
  • 220
    • 0029926552 scopus 로고    scopus 로고
    • HIV-1 membrane fusion mechanism structural studies of the interactions between biologically-active peptides from gp41
    • (1996) Biochemistry , vol.35 , pp. 13697-13708
    • Lawless, M.K.1
  • 221
    • 0031729823 scopus 로고    scopus 로고
    • Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41 mediated virus entry
    • (1998) Nat Med , vol.4 , pp. 1302-1307
    • Kilby, J.M.1
  • 222
    • 0035313589 scopus 로고    scopus 로고
    • Human immunodeficiency virus Type 1 entry inhibitors PRO542 and T20 are potentially synergistic in blocking virus cell and cell-cell fusion
    • (2001) J Infect Dis , vol.183 , pp. 1121-1125
    • Nakashima, K.1
  • 223
    • 0035940445 scopus 로고    scopus 로고
    • SCH-C (SCH 351125), an orally bioavailable, small molecule antagonist of the chemokine receptor CCR5, is a potent inhibitor of HIV-1 infection in vitro and in vivo
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 12718-12723
    • Strizki, J.M.1
  • 224
    • 0037039380 scopus 로고    scopus 로고
    • HIV-1 escape from a small molecule, CCR5-specific entry inhibitor does not involve CXCR4 use
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 395-400
    • Trkola, A.1
  • 226
  • 227
    • 0023256678 scopus 로고
    • Prospects for the control of AIDS by immunizing seropositive individuals
    • (1987) Nature , vol.317 , pp. 473-476
    • Salk, J.1
  • 228
    • 0025764679 scopus 로고
    • A phase 1 evaluation of safety and immunogenicity of vaccination with recombinant gp160 in patients with early HIV infection
    • (1991) N Engl J Med , vol.324 , pp. 1677-1684
    • Redfield, R.R.1
  • 231
    • 0028170090 scopus 로고
    • A randomized, placedo-controlled, blind anti-AIDS clinical trial: Safety and immunogenicity of a specific anti-IFN-α immunization
    • (1994) J AIDS , vol.7 , pp. 978-988
    • Gringeri, A.1
  • 232
    • 0029303388 scopus 로고
    • Anti-alpha interferon immunization: Safety and immunogenicity in asymptomatic HIV positive patients at high risk of disease progression
    • (1995) Cell Mol Biol , vol.41 , pp. 381-387
    • Gringeri, A.1
  • 233
  • 234
    • 1542429111 scopus 로고
    • Absence of clinical virological and immunological signs of progression in HIV-1 infected patients receiving active anti-alpha interferon immunization: A 30 month follow-up report
    • (1995) J AIDS , vol.13 , pp. 55-67
    • Gringeri, A.1
  • 235
    • 0032057287 scopus 로고    scopus 로고
    • Safety and immunogenicity of HIV-1 tax toxoid in immunocompromised HIV-1-infected patients
    • (1998) J Hum Virol , vol.1 , pp. 293-298
    • Gringeri, A.1
  • 237
    • 0032311194 scopus 로고    scopus 로고
    • A prophylactic and therapeutic AIDS vaccine containing as a component the innocuous tax toxoid
    • (1998) Biomed Pharmacother , vol.52 , pp. 431-435
    • Le Buanec, H.1
  • 238
    • 0030722896 scopus 로고    scopus 로고
    • Inhibition of HIV-1 infection by the β-chemokine MDC
    • (1997) Science , vol.278 , pp. 695-698
    • Pal, R.1
  • 240
    • 0025743306 scopus 로고
    • Importance of the nef gene for maintenance of high virus loads and for development of AIDS
    • (1991) Cell , vol.65 , pp. 651-652
    • Kestler H.W. III1
  • 242
    • 0032905068 scopus 로고    scopus 로고
    • Live attenuated, multiply deleted simian immunodeficiency virus causes AIDS in infant and adult macaques
    • (1999) Nat Med , vol.5 , pp. 194-203
    • Baba, T.W.1
  • 244
    • 0035815437 scopus 로고    scopus 로고
    • Control of a mucosal challenge and prevention of AIDS by a multiprotein DNA/MVA vaccine
    • (2001) Science , vol.292 , pp. 69-74
    • Amara, R.R.1
  • 245
    • 0037122719 scopus 로고    scopus 로고
    • Replication-incompetent adenoviral vaccine vector elicits effective anti-immunodeficiency-virus immunity
    • (2002) Nature , vol.415 , pp. 331-335
    • Shiver, J.W.1
  • 246
    • 0033766645 scopus 로고    scopus 로고
    • Control of viremia and prevention of clinical AIDS in rhesus monkeys by cytokine-augmented DNA vaccination
    • (2002) Science , vol.290 , pp. 486-492
    • Barouch, D.N.1
  • 247
    • 0029078329 scopus 로고
    • Repeated exposure of rhesus macaques to low doses of SIV did not protect them against the consequences of a high dose SIV challenge
    • (1995) J Gen Virol , vol.76 , pp. 1307-1315
    • Dittmer, U.1
  • 248
    • 0027203733 scopus 로고
    • Cellular immune response to SIVmac and HIV-2 in macaques: Model for the human HIV-1 infection
    • (1993) J AIDS , vol.6 , pp. 969-976
    • Voss, G.1    Hunsman, G.2
  • 249
    • 0032543307 scopus 로고    scopus 로고
    • Structure of an HIV gp-120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody
    • (1998) Nature , vol.393 , pp. 648-659
    • Kwong, P.D.1
  • 250
    • 0028865465 scopus 로고
    • Cross clade neutralization of primary isolates of HIV-1 by human monoclonal antibodies and tetrameric CD4-IgG
    • (1995) J Virol , vol.69 , pp. 6609-6617
    • Trkola, A.1
  • 251
    • 0033985999 scopus 로고    scopus 로고
    • A recombinant human immunodeficiency virus type 1 envelope glycoprotein complex stabilized by an intermolecular disulfide bond between the gp 120 and gp 41 subunits is an antigenic mimic of the trimeric virion-associated structure
    • (2000) J Virol , vol.74 , pp. 627-643
    • Binley, J.M.1
  • 252
    • 0034063445 scopus 로고    scopus 로고
    • Variable-loop-deleted variants of the human immunodeficiency virus type 1 envelope glycoprotein can be stabilized by an intermolecular disulfide bond between the gp120 and gp41 subunits
    • (2000) J Virol , vol.74 , pp. 5091-5100
    • Sanders, R.W.1
  • 254
    • 0037165309 scopus 로고    scopus 로고
    • AIDS vaccines: On the trail of two trials
    • (2002) Nature , vol.415 , pp. 365-366
    • Moore, J.P.1
  • 256
    • 0026657688 scopus 로고
    • Improbability of effective vaccination against HIV because of its intracellular transmission and rectal portal entry
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 8852-8855
    • Sabin, A.1
  • 258
    • 0035031924 scopus 로고    scopus 로고
    • Identification of a novel post-transcriptional regulatory element by using a rev and RRE-mutated HIV-1 DNA proviral clone as a molecular trap
    • (2001) J Virol , vol.75 , pp. 4558-4569
    • Nappi, F.1


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