Inhibition of the neutral magnesium-dependent sphingomyelinase by glutathione

Journal of Biological Chemistry

Volumn 272, Issue 26, 1997, Pages 16281-16287

  Liu, Bin ^a   Hannun, Yusuf A ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BUTHIONINE SULFOXIMINE; CERAMIDE; DITHIOTHREITOL; GAMMA GLUTAMYLCYSTEINE; GLUTATHIONE; MAGNESIUM; MERCAPTOETHANOL; SPHINGOMYELIN; SPHINGOMYELIN PHOSPHODIESTERASE; THIOL DERIVATIVE;

APOPTOSIS; ARTICLE; CELL CYCLE; CELL DAMAGE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; GLUTATHIONE METABOLISM; HUMAN; HUMAN CELL; LEUKEMIA CELL; OXIDATIVE STRESS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

BUTHIONINE SULFOXIMINE; DITHIOTHREITOL; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUTATHIONE; HUMANS; MAGNESIUM; SPHINGOMYELIN PHOSPHODIESTERASE; TUMOR CELLS, CULTURED;

EID: 0030960327     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.26.16281     Document Type: Article

References (52)

1. Okazaki, T., Bell, R. M., and Hannun, Y. A. (1989) J. Biol. Chem. 264, 19076-19080
2. Kim, M.-Y., Linardic, C., Obeid, L., and Hannun, Y. (1991) J. Biol. Chem. 266, 484-489
3. Ballou, L. R., Chao, C. P., Holness, M. A., Barker, S. C., and Raghow, R. (1992) J. Biol. Chem. 267, 20044-20050
4. Mathias, S., Younes, A., Kan, C.-C., Orlow, I., Joseph, C., and Kolesnick, R. N. (1993) Science 259, 519-522
5. Dobrowsky, R. T., Werner, M. H., Castellino, A. M., Chao, M. V., and Hannun, Y. A. (1994) Science 265, 1596-1599
6. Strum, J. C., Small G. W., Pauig, S. B., and Daniel, L. W. (1994) J. Biol. Chem. 269, 15493-15497
7. Zhang, J., Alter, N., Reed, J. C., Borner C., Obeid, L. M., and Hannun, Y. A. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 5325-5328
8. Jayadev, S., Liu, B., Bielawska, A. E., Lee, J. Y., Nazaire, F., Pushkareva, M. Y., Obeid, L. M., and Hannun, Y. A. (1995) J. Biol. Chem. 270, 2047-2052
9. Hannun, Y. A. (1994) J. Biol. Chem. 269, 3125-3128
10. Spence M. W. (1993) Adv. Lipid Res. 26, 3-23
11. Quintern, L. E., Weitz, G., Nehrkorn, H., Tager, J. M., Schram, A. W., and Sandhoff, K. (1987) Biochim. Biophys. Acta 922, 323-336
12. Kitagawa, T. (1987) Jpn. J. Hum. Genet. 32, 55-69
13. Haimovitz-Friedman, A., Kan, C.-C., Ehleiter, D., Persaud, R. S.., McLoughlin, M., Fuks, Z., and Kolesnick, R. N. (1994) J. Exp. Med. 180, 525-535
14. Cifone, M. G., De Maria, R., Roncaioli, P., Rippo, M. R., Azuma, M., Lanier, L. L., Santoni, A., and Testi, R. (1994) J. Exp. Med. 180, 1547-1552
15. Schutze, S., Potthof, K., Machleidt, T., Berkovic, D., Wiegmann, K., and Kronke, M. (1992) Cell 71, 765-776
16. Chatterjee, S. (1993) Adv. Lipid Res. 26, 25-47
17. Tepper, C. G., Jayadev, S., Liu, B., Bielawska, A., Wolff, R. A., Yonehara, S., Hannun, Y. A., and Seldin, M. F. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 8443-8447
18. Wiegmann, K., Schutze, S., Machleidt, T., Witte, D., and Kronke, M. (1992) Cell 78, 1005-1015
19. Okazaki, T., Bielawska, A., Domae, N., Bell, R. M., and Hannun, Y. A. (1994) J. Biol. Chem. 269, 4070-4077
20. Spence, M. W., Byers, D. M., Palmer, F. B. St. C., and Cook, H. W. (1989) J. Biol. Chem. 264, 5358-5363
21. Schiessel, S. L., Schuchman, E. H., Williams, K., J., and Tabas, I. (1996) J. Biol. Chem. 271, 18431-18436
22. Nyberg, L., Duan, R. D., Axelson, J., and Nilsson, A. (1996) Biochim. Biophys. Acta 1300, 42-48
23. Meister, A. (1995) Methods Enzymol. 251, 3-7
24. Yamanaka, T., and Suzuki, K. (1982) J. Neurochem. 38, 1753-1764
25. Halliwell, B., and Gutteridge, J. M. C. (1989) Free Radicals in Biology and Medicine, 2nd Ed., Clarendon Press, Oxford
26. Meister, A. (1983) Science 220, 472-477
27. Slater, A. F. G., Stefan, C., Nobel, I., van den Dobblelsteen, D. J., and Orrenius, S. (1995) Toxicol. Lett. 82, 149-153
28. Christie, N. A., Slutsky, A. S., Freeman, B. A., and Tanswell, A. K. (1994) Arch. Biochem. Biophys. 313, 131-138
29. Fernandes, R. S., and Cotter, T. G. (1994) Biochem. Pharmacol. 48, 675-681
30. Ghibelli, L., Coppola, S., Rotilio, G., Lafavia, E., Maresca, V., and Ciriolo, M. R. (1995) Biochem. Biophys. Res. Commun. 216, 313-320
31. Beaver, J. P., and Waring, P. (1995) Eur. J. Cell Biol. 68, 47-54
32. Levine, E. S., Friedman, H. S., Griffith, O. W., Colvin, O. M., Raynor, J. H., and Lieberman, M. (1993) Cardiovasc. Res. 27, 1248-1253
33. Kane, D. J., Sarafian, T. A., Anton, R., Hahn, H., Gralla, E. B., Valentine, J. S., Ord, T., and Bredesen, D. E. (1993) Science 262, 1274-1277
34. Chiba, T., Takahashi, S., Sato, N., Ishii, S., and Kikuchi, K. (1996) Eur. J. Immunol. 26, 1164-1169
35. Obeid, L. M., Linardic, C. M., Karolak, L. A., and Hannun, Y. A. (1993) Science 259, 1769-1771
36. Dbaibo, G., Pushkareva, M. Y., Jayadev, S., Schwartz, J. K., Horowitz, J. M., Obeid, L. M., and Hannun, Y. A. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 1347-1351
37. Dobrowsky, R. T., and Hannun, Y. A. (1992) J. Biol. Chem. 267, 5048-5051
38. Mathias, S., Dressler, K. A., and Kolesnick, R. N. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 10009-10013
39. Lee, J. Y., Hannun, Y. A., and Obeid, L. M. (1996) J. Biol. Chem. 271, 13169-13174
40. Venable, M. E., Bielawska, A., and Obeid, L. M. (1996) J. Biol. Chem. 271, 24800-24805
41. Venable, M. E., Lee, J. Y., Smyth, M. J., Bielawska, A., and Obeid, L. M. (1995) J. Biol. Chem. 270, 30701-30708
42. Bannai, S., and Kitamura, E. (1980) J. Biol. Chem. 255, 2372-2376
43. Lu, S. C., Ge, J.-L., Kuhlenkamp, J., and Kaplowitz, N. (1992) J. Clin. Invest. 90, 524-532
44. Mutoh, H., Ota, S., Hiraishi, H., Ivey, K. J., Terano, A., and Sugimoto, T. (1991) Am. J. Physiol. 261, G65-G70
45. Gerard-Monnier, D., Fougeat, S., and Chaudiere, J. (1992) Biochem. Pharmacol. 43, 451-456
46. Pierson, H. F., Fisher, J. M., and Rabinovitz, M. (1985) Cancer Res. 45, 4727-4731
47. Gilbert, H. F. (1990) Adv. Enzymol. 63, 69-85
48. Tate, S. S., and Meister, A. (1974) J. Biol. Chem. 249, 7593-7602
49. Bligh, E. G., and Dyer, W. J. (1959) Can. J. Biochem. Physiol. 37, 911-917
50. Griffith, O. W. (1980) Anal. Biochem. 106, 207-212
51. Tietze, F. (1969) Anal. Biochem. 27, 502-522
52. Bradford, M. M. (1976) Anal. Biochem. 72, 248-254