Cloning and characterization of a novel human alkaline ceramidase: A mammalian enzyme that hydrolyzes phytoceramide

Journal of Biological Chemistry

Volumn 276, Issue 28, 2001, Pages 26577-26588

  Mao, Cungui ^a,b   Xu, Ruijuan ^a   Szulc, Zdzislaw M ^a   Bielawska, Alicja ^a   Galadari, Sehamuddin H ^c   Obeid, Lina M ^a,b  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^c UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; CELLS; ENZYME KINETICS; GENETIC ENGINEERING; HYDROLYSIS; PROTEINS; YEAST;

GOLGI APPARATUS;

BIOCHEMISTRY;

ACYLSPHINGOSINE DEACYLASE; CALCIUM ION; CERAMIDE; COMPLEMENTARY DNA; GREEN FLUORESCENT PROTEIN; INOSITOL; LIPID; PALMITIC ACID; PHYTOCERAMIDE; RNA; SPHINGOLIPID; TRITIUM; UNCLASSIFIED DRUG; AMIDASE;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; EMBRYO; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYME SUBSTRATE; GENE OVEREXPRESSION; GOLGI COMPLEX; HUMAN; HUMAN CELL; HYDROLYSIS; IMMUNOPRECIPITATION; ISOTOPE LABELING; KIDNEY CELL; MOLECULAR CLONING; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PH; PLACENTA; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY; WESTERN BLOTTING; YEAST CELL; GENETICS; HYDROXYLATION; METABOLISM; MOLECULAR GENETICS; SEQUENCE ALIGNMENT;

ANIMALIA; GYMNOMYZA SAMOENSIS; MAMMALIA; SPHINGIODEA;

AMIDOHYDROLASES; AMINO ACID SEQUENCE; BASE SEQUENCE; CERAMIDES; CLONING, MOLECULAR; HUMANS; HYDROXYLATION; MOLECULAR SEQUENCE DATA; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY;

EID: 0035854766     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M102818200     Document Type: Article

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