Novel antifolate resistant mutations of Plasmodium falciparum dihydrofolate reductase selected in Escherichia coli

Molecular and Biochemical Parasitology

Volumn 120, Issue 1, 2002, Pages 61-72

  Chusacultanachai, Sudsanguan ^a   Thiensathit, Pornpan ^b   Tarnchompoo, Bongkoch ^a   Sirawaraporn, Worachart ^b   Yuthavong, Yongyuth ^a  

^a NATIONAL SCIENCE AND TECHNOLOGY DEVELOPMENT AGENCY   (Thailand)

^b MAHIDOL UNIVERSITY   (Thailand)

Author keywords

Antifolate resistant mutants; Dihydrofolate reductase; Malaria

Indexed keywords

4,6 DIAMINO 1,2 DIHYDRO 2,2 DIMETHYL 1 [3 (2,4,5 TRICHLOROPHENOXY)PROPOXY] 1,3,5 TRIAZINE; AMINE; ANTIMALARIAL AGENT; DIHYDROFOLATE REDUCTASE; DIHYDROFOLATE REDUCTASE INHIBITOR; ENZYME INHIBITOR; FOLIC ACID ANTAGONIST; PYRIMETHAMINE; SULFATE; SYNTHETIC DNA; TRIMETHOPRIM;

ARTICLE; CONTROLLED STUDY; DNA TEMPLATE; DRUG BINDING; DRUG RESISTANCE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SUBSTRATE COMPLEX; ESCHERICHIA COLI; GENE MUTATION; GENETIC CODE; GENETIC COMPLEMENTATION; HOST CELL; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; PLASMODIUM FALCIPARUM;

EID: 0036182285     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-6851(01)00440-6     Document Type: Article

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