메뉴 건너뛰기




Volumn 55, Issue 2, 1996, Pages 209-213

Point mutations in the dihydrofolate reductase and dihydropteroate synthetase genes and in vitro susceptibility to pyrimethamine and cycloguanil of Plasmodium falciparum isolates from Papua New Guinea

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOGUANIL; DIHYDROFOLATE REDUCTASE; DIHYDROPTEROATE SYNTHASE; PYRIMETHAMINE;

EID: 0029775095     PISSN: 00029637     EISSN: None     Source Type: Journal    
DOI: 10.4269/ajtmh.1996.55.209     Document Type: Article
Times cited : (109)

References (26)
  • 1
    • 0001651897 scopus 로고
    • Molecular cloning and sequence analysis of the Plasmodium falciparum dihydrofolate reductase-thymidylate synthase gene
    • Bzik DJ, Li W-B, Horii T, Inselburg J, 1987. Molecular cloning and sequence analysis of the Plasmodium falciparum dihydrofolate reductase-thymidylate synthase gene. Proc Natl Acad Sci USA 84: 8360-8364.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 8360-8364
    • Bzik, D.J.1    Li, W.-B.2    Horii, T.3    Inselburg, J.4
  • 2
    • 0000854414 scopus 로고
    • Amino acid changes linked to pyrimethamine resistance in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum
    • Cowman AF, Morry MJ, Biggs BA, Cross GAM, Foote SJ, 1988. Amino acid changes linked to pyrimethamine resistance in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum. Proc Natl Acad Sci USA 85: 9109-9113.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 9109-9113
    • Cowman, A.F.1    Morry, M.J.2    Biggs, B.A.3    Cross, G.A.M.4    Foote, S.J.5
  • 3
    • 0000841123 scopus 로고
    • Evidence that a point mutation in dihydrofolate reductase-thymidylate synthase confers resistance to pyrimethamine in falciparum malaria
    • Peterson DS, Walliker D, Wellems TE, 1988. Evidence that a point mutation in dihydrofolate reductase-thymidylate synthase confers resistance to pyrimethamine in falciparum malaria. Proc Natl Acad Sci USA 85: 9114-9118.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 9114-9118
    • Peterson, D.S.1    Walliker, D.2    Wellems, T.E.3
  • 4
    • 0024584012 scopus 로고
    • Characterization of the dihydrofolate reductase-thymidylate synthetase gene from human malaria parasites highly resistant to pyrimethamine
    • Snewin VA, England SM, Sims PF, Hyde JE, 1989. Characterization of the dihydrofolate reductase-thymidylate synthetase gene from human malaria parasites highly resistant to pyrimethamine. Gene 76: 41-52.
    • (1989) Gene , vol.76 , pp. 41-52
    • Snewin, V.A.1    England, S.M.2    Sims, P.F.3    Hyde, J.E.4
  • 5
    • 0024460302 scopus 로고
    • Point mutations in the dihydrofolate reductase-thymidylate synthase gene as the molecular basis for pyrimethamine resistance in Plasmodium falciparum
    • Zolg JW, Plitt JR, Chen GX, Palmer S, 1989. Point mutations in the dihydrofolate reductase-thymidylate synthase gene as the molecular basis for pyrimethamine resistance in Plasmodium falciparum. Mol Biochem Parasitol 36: 253-262.
    • (1989) Mol Biochem Parasitol , vol.36 , pp. 253-262
    • Zolg, J.W.1    Plitt, J.R.2    Chen, G.X.3    Palmer, S.4
  • 6
    • 0025605441 scopus 로고
    • Heterologous expression of active thymidylate synthase-dihydrofolate reductase from Plasmodium falciparum
    • Sirawaraporn W, Sirawaraporn R, Cowman AF, Yuthavong Y, Santi DV, 1990. Heterologous expression of active thymidylate synthase-dihydrofolate reductase from Plasmodium falciparum. Biochemistry 29: 10779-10785.
    • (1990) Biochemistry , vol.29 , pp. 10779-10785
    • Sirawaraporn, W.1    Sirawaraporn, R.2    Cowman, A.F.3    Yuthavong, Y.4    Santi, D.V.5
  • 8
    • 0028872311 scopus 로고
    • Point mutations in the dihydrofolate reductase-thymidylate synthase gene and pyrimethamine and cycloguanil resistance in Plasmodium falciparum
    • Basco LK, de Pecoulas PE, Wilson CM, Le Bras J, Mazabraud A, 1995. Point mutations in the dihydrofolate reductase-thymidylate synthase gene and pyrimethamine and cycloguanil resistance in Plasmodium falciparum. Mol Biochem Parasitol 69: 135-138.
    • (1995) Mol Biochem Parasitol , vol.69 , pp. 135-138
    • Basco, L.K.1    De Pecoulas, P.E.2    Wilson, C.M.3    Le Bras, J.4    Mazabraud, A.5
  • 9
    • 0025263958 scopus 로고
    • Amino acids in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum involved in cycloguanil resistance differ from those involved in pyrimethamine resistance
    • Foote SJ, Galatis D, Cowman AF, 1990. Amino acids in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum involved in cycloguanil resistance differ from those involved in pyrimethamine resistance. Proc Natl Acad Sci USA 87: 3014-3017.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 3014-3017
    • Foote, S.J.1    Galatis, D.2    Cowman, A.F.3
  • 10
    • 0025252334 scopus 로고
    • Molecular basis of differential resistance to cycloguanil and pyrimethamine in Plasmodium falciparum malaria
    • Peterson DS, Milhous WK, Wellems TE, 1990. Molecular basis of differential resistance to cycloguanil and pyrimethamine in Plasmodium falciparum malaria. Proc Natl Acad Sci USA 87: 3018-3022.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 3018-3022
    • Peterson, D.S.1    Milhous, W.K.2    Wellems, T.E.3
  • 11
    • 0021249879 scopus 로고
    • Synergistic antimalarial activity of pyrimethamine and sulfadoxine against Plasmodium falciparum in vitro
    • Chulay JD, Watkins WM, Sixsmith DG, 1984. Synergistic antimalarial activity of pyrimethamine and sulfadoxine against Plasmodium falciparum in vitro. Am J Trop Med Hyg 33: 325-330.
    • (1984) Am J Trop Med Hyg , vol.33 , pp. 325-330
    • Chulay, J.D.1    Watkins, W.M.2    Sixsmith, D.G.3
  • 12
    • 0028291789 scopus 로고
    • Primary structure and expression of the dihydropteroate synthetase gene of Plasmodium falciparum
    • Triglia T, Cowman AF, 1994. Primary structure and expression of the dihydropteroate synthetase gene of Plasmodium falciparum. Proc Natl Acad Sci USA 91: 7141-7153.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 7141-7153
    • Triglia, T.1    Cowman, A.F.2
  • 13
    • 0028021624 scopus 로고
    • Sequence variation in the hydroxymethyldihydropterin pyrophosphokinase: Dihydropteroate synthase gene in lines of the human malaria parasite, Plasmodium falciparum, with differing resistance to sulfadoxine
    • Brooks D, Wang P, Read M, Watkin W, Sims P, Hyde J, 1994. Sequence variation in the hydroxymethyldihydropterin pyrophosphokinase: dihydropteroate synthase gene in lines of the human malaria parasite, Plasmodium falciparum, with differing resistance to sulfadoxine. Eur J Biochem 224: 397-405.
    • (1994) Eur J Biochem , vol.224 , pp. 397-405
    • Brooks, D.1    Wang, P.2    Read, M.3    Watkin, W.4    Sims, P.5    Hyde, J.6
  • 14
    • 0029013280 scopus 로고
    • A mutation-specific PCR system to detect sequence variation in the dihydropteroate synthetase gene of Plasmodium falciparum
    • Wang P, Brooks DR, Sims PFG, Hyde JE, 1995. A mutation-specific PCR system to detect sequence variation in the dihydropteroate synthetase gene of Plasmodium falciparum. Mol Biochem Parasitol 75: 115-125.
    • (1995) Mol Biochem Parasitol , vol.75 , pp. 115-125
    • Wang, P.1    Brooks, D.R.2    Sims, P.F.G.3    Hyde, J.E.4
  • 15
    • 0029103108 scopus 로고
    • The epidemiology of malaria in the Wosera area, East Sepik Province, Papua New Guinea, in preparation for vaccine trials I. Malariometric indices and immunity
    • Genton B, Al-Yaman F, Beck H-P, Hii J, Mellor S, Narara A, Gibson N, Smith T, Alpers MP, 1995. The epidemiology of malaria in the Wosera area, East Sepik Province, Papua New Guinea, in preparation for vaccine trials I. Malariometric indices and immunity. Ann Trop Med Parasitol 89: 359-376.
    • (1995) Ann Trop Med Parasitol , vol.89 , pp. 359-376
    • Genton, B.1    Al-Yaman, F.2    Beck, H.-P.3    Hii, J.4    Mellor, S.5    Narara, A.6    Gibson, N.7    Smith, T.8    Alpers, M.P.9
  • 16
    • 0029113129 scopus 로고
    • The epidemiology of malaria in the Wosera area, East Sepik Province, Papua New Guinea, in preparation for vaccine trials. II. Mortality and morbidity
    • Genton B, Al-Yaman F, Beck H-P, Hii J, Mellor S, Rare L, Ginny M, Smith T, Alpers MP, 1995. The epidemiology of malaria in the Wosera area, East Sepik Province, Papua New Guinea, in preparation for vaccine trials. II. Mortality and morbidity. Ann Trop Med Parasitol 89: 377-390.
    • (1995) Ann Trop Med Parasitol , vol.89 , pp. 377-390
    • Genton, B.1    Al-Yaman, F.2    Beck, H.-P.3    Hii, J.4    Mellor, S.5    Rare, L.6    Ginny, M.7    Smith, T.8    Alpers, M.P.9
  • 17
    • 0028402812 scopus 로고
    • Resistance of Plasmodium falciparum in vivo to 3 days' treatment with quinine and single-dose Fansidar
    • Al-Yaman F, Genton B, Mokela D, Alpers MP, 1994. Resistance of Plasmodium falciparum in vivo to 3 days' treatment with quinine and single-dose Fansidar. P N G Med J 37: 54-56.
    • (1994) P N G Med J , vol.37 , pp. 54-56
    • Al-Yaman, F.1    Genton, B.2    Mokela, D.3    Alpers, M.P.4
  • 19
    • 0018262277 scopus 로고
    • Drug sensitivity of Plasmodium falciparum: An in vitro microtechnique
    • Rieckmann KH, Sax LJ, Campbell GH, Mrema JE, 1978. Drug sensitivity of Plasmodium falciparum: an in vitro microtechnique. Lancet i: 22-23.
    • (1978) Lancet i , pp. 22-23
    • Rieckmann, K.H.1    Sax, L.J.2    Campbell, G.H.3    Mrema, J.E.4
  • 20
    • 0020644871 scopus 로고
    • The activity of pyrimethamine and sulphadoxine against Plasmodium falciparum determined by the in vitro microtechnique
    • Eastham GN, Rieckman KH, 1983. The activity of pyrimethamine and sulphadoxine against Plasmodium falciparum determined by the in vitro microtechnique. Trans R Soc Trop Med Hyg 77: 91-93.
    • (1983) Trans R Soc Trop Med Hyg , vol.77 , pp. 91-93
    • Eastham, G.N.1    Rieckman, K.H.2
  • 22
    • 0002049851 scopus 로고
    • Amplifying ancient DNA
    • Innis MA, Gelfand DH, Sninsky JJ, White TJ, eds. San Diego: Academic Press, Inc.
    • Paabo S, 1990. Amplifying ancient DNA. Innis MA, Gelfand DH, Sninsky JJ, White TJ, eds. PCR Protocols. A Guide to Methods and Applications. San Diego: Academic Press, Inc., 159-166.
    • (1990) PCR Protocols. A Guide to Methods and Applications , pp. 159-166
    • Paabo, S.1
  • 23
    • 0028230794 scopus 로고
    • In vitro activity of pyrimethamine, cycloguanil, and other antimalarial drugs against African isolates and clones of Plasmodium falciparum
    • Basco LK, Ramiliarisoa O, Le Bras J, 1994. In vitro activity of pyrimethamine, cycloguanil, and other antimalarial drugs against African isolates and clones of Plasmodium falciparum. Am J Trop Med Hyg 50: 193-199.
    • (1994) Am J Trop Med Hyg , vol.50 , pp. 193-199
    • Basco, L.K.1    Ramiliarisoa, O.2    Le Bras, J.3
  • 24
    • 0026006245 scopus 로고
    • Prevalence of the dihydrofolate reductase Asn-108 mutation as the basis for pyrimethamine-resistant falciparum malaria in the Brazilian Amazon
    • Peterson DS, Di SS, Povoa M, Calvosa VS, Do RV, Wellems TE, 1991. Prevalence of the dihydrofolate reductase Asn-108 mutation as the basis for pyrimethamine-resistant falciparum malaria in the Brazilian Amazon. Am J Trop Med Hyg 45: 492-497.
    • (1991) Am J Trop Med Hyg , vol.45 , pp. 492-497
    • Peterson, D.S.1    Di, S.S.2    Povoa, M.3    Calvosa, V.S.4    Do, R.V.5    Wellems, T.E.6
  • 25
    • 0025138661 scopus 로고
    • Dihydrofolate reductase mutations and chromosomal changes associated with pyrimethamine resistance of Plasmodium falciparum
    • Tanaka M, Gu HM, Bzik DJ, Inselburg JW, 1990. Dihydrofolate reductase mutations and chromosomal changes associated with pyrimethamine resistance of Plasmodium falciparum. Mol Biochem Parasitol 39: 127-134.
    • (1990) Mol Biochem Parasitol , vol.39 , pp. 127-134
    • Tanaka, M.1    Gu, H.M.2    Bzik, D.J.3    Inselburg, J.W.4
  • 26
    • 0029050608 scopus 로고
    • Pyrimethamine and proguanil resistance-conferring mutations in Plasmodium falciparum dihydrofolate reductase: Polymerase chain reaction methods for surveillance in Africa
    • Plowe CV, Djimde A, Bouare M, Doumbo O, Wellems TE, 1995. Pyrimethamine and proguanil resistance-conferring mutations in Plasmodium falciparum dihydrofolate reductase: polymerase chain reaction methods for surveillance in Africa. Am J Trop Med Hyg 52: 565-568.
    • (1995) Am J Trop Med Hyg , vol.52 , pp. 565-568
    • Plowe, C.V.1    Djimde, A.2    Bouare, M.3    Doumbo, O.4    Wellems, T.E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.