How the gut senses its content

Cellular Microbiology

Volumn 4, Issue 2, 2002, Pages 61-72

  Didierlaurent, Arnaud ^a   Sirard, Jean Claude ^a   Kraehenbuhl, Jean Pierre ^a   Neutra, Marian R ^b  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA DEFENSIN; B7 ANTIGEN; BACTERIUM LIPOPOLYSACCHARIDE; BETA DEFENSIN; CD40 ANTIGEN; CECROPIN; CHEMOKINE; CYTOKINE; DEFENSIN; LACTOFERRIN; LIPOPROTEIN; LYSOZYME; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PEPTIDOGLYCAN; TEICHOIC ACID;

ANTIGEN PRESENTING CELL; ANTIGEN SPECIFICITY; ANTIMICROBIAL ACTIVITY; BACTERIAL VIRULENCE; BACTERIUM ADHERENCE; COMMENSALISM; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; EPITHELIUM CELL; FUNGUS; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HOST RESISTANCE; HUMAN; IMMUNITY; INTESTINE EPITHELIUM; INTESTINE FLORA; INTESTINE MUCOSA; INTESTINE VILLUS; MACROPHAGE; MONOCYTE; MYCOBACTERIUM; NONHUMAN; PATHOGENICITY; PEYER PATCH; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SALMONELLA TYPHIMURIUM; SHORT SURVEY; SIGNAL TRANSDUCTION; STOMACH CONTENT; VIRUS VIRULENCE;

ANIMALS; ANTIGENS; BACTERIA; HUMANS; IMMUNITY, ACTIVE; IMMUNITY, CELLULAR; IMMUNITY, NATURAL; INTESTINAL MUCOSA; VIRUSES;

BACTERIA (MICROORGANISMS); FUNGI; MYCOBACTERIUM; NEGIBACTERIA; POSIBACTERIA; SALMONELLA TYPHIMURIUM;

EID: 0036118431     PISSN: 14625814     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1462-5822.2002.00177.x     Document Type: Short Survey

References (117)

1. Toll-like receptors in the induction of the innate immune response
2. Recognition of double-stranded RNA and activation of NF-kappa B by Toll-like receptor 3
3. Identical T cell clones are located within the mouse gut epithelium and lamina propria and circulate in the thoracic duct lymph
4. Secretion of microbicidal alpha-defensins by intestinal Paneth cells in response to bacteria
5. Cytotoxic T-cell response to respiratory syncytial virus in mice
6. Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition
7. Mucosal AIDS vaccine reduces disease and viral load in gut reservoir and blood after mucosal infection of macaques
8. The indigenous gastrointestinal microflora
9. Antigen presentation by intestinal epithelial cells
10. Innate immunity and the normal microflora
11. Regional specialization in the mucosal immune system: Primed cells do not always home along the same track
12. MAdCAM-1 has homology to immunoglobulin and mucin-like adhesion receptors and to lgA1
13. Intraepithelial lymphocytes traffic to the intestine and enhance resistance to Toxoplasma gondii oral infection
14. Differential alteration in intestinal epithelial cell expression of toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease
15. Lipopolysaccharide activates distinct signaling pathways in intestinal epithelial cell lines expressing toll-like receptors
16. Migration kinetics and final destination of type 1 and type 2 CD8 effector cells predict protection against pulmonary virus infection
17. Predominant T-cell receptor Vbeta usage of intraepithelial lymphocytes during the immune response to enteric reovirus infection
18. The intestinal epithelial cell: Immunological aspects
19. CCR6 mediates dendritic cell localization, lymphocyte homeostasis, and immune responses in mucosal tissue
20. Mucins and mucosal protection in the gastrointestinal tract: New prospects for mucins in the pathology of gastrointestinal disease
21. Plant pathogens and integrated defence responses to infection
22. Molecular basis of the interaction of Salmonella with the intestinal mucosa
23. Exosome: From internal vesicle of the multivesicular body to intercellular signaling device
24. Flagellin, a novel mediator of Salmonella-induced epithelial activation and systemic inflammation: I kappa B alpha degradation, induction of nitric oxide synthase, induction of proinflammatory mediators, and cardiovascular dysfunction
25. Epithelial cells secrete the chemokine interleukin-8 in response to bacterial entry
26. NF-kappa B is a central regulator of the intestinal epithelial cell innate immune response induced by infection with enteroinvasive bacterial
27. In situ class switching and differentiation to lgA-producing cells in the gut lamina propria
28. Immunoglobulin A cell distribution in the human small intestine: Phenotypic and functional characteristics
29. Plants have a sensitive perception system for the most conserved domain of bacterial flagellin
30. Common themes in microbial pathogenicity revisited
31. Immunity to rotavirus infection in mice
32. Role of the glycocalyx in regulating access of microparticles to apical plasma membranes of intestinal epithelial cells - Implications for microbial attachment and oral vaccine targeting
33. CD14 is expressed and released as soluble CD14 by human intestinal epithelial cells in vitro: Lipopolysaccharide activation of epithelial cells revisited
34. Oral tolerance
35. Bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression
36. 2+-mediated activation of the NF-kappa B pathway
37. Salmonella typhimurium translocates flagellin across intestinal epithelia, inducing a proinflammatory response
38. Regional differences in glycoconjugates of intestinal M cells in mice: Potential targets for mucosal vaccines
39. CARD4/Nod1 mediates NF-kappa B and JNK activation by invasive Shigella flexneri
40. Both the extracellular leucine-rich repeat domain and the kinase activity of FLS2 are required for flagellin binding and signaling in arabidopsis
41. Abrogation of TGFbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease
42. Contribution of double-negative thymic precursors to CD8 alpha alpha (+) intraepithelial lymphocytes of the gut in mice bearing TCR transgenes
43. In situ detection of virus- and tumor-specific T-cell immunity
44. S. typhimurium encodes an activator of Rho GTPases that induces membrane ruffling and nuclear responses in host cells
45. CD8 (+) T cell effector mechanisms in resistance to infection
46. The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5
47. A Toll-like receptor recognizes bacterial DNA
48. Intestinal epithelial cells use two distinct pathways for HLA class II antigen processing
49. Phylogenetic perspectives in innate immunity
50. Molecular analysis of commensal host-microbial relationships in the intestine
51. A molecular sensor that allows a gut commensal to control its nutrient foundation in a competitive ecosystem
52. The c5a chemoattractant receptor mediates mucosal defence to infection
53. A recombinant Salmonella typhimurium vaccine strain is taken up and survives within murine Peyer's patch dendritic cells
54. A discrete subpopulation of dendritic cells transports apoptotic intestinal epithelial cells to T cell areas of mesenteric lymph nodes
55. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
56. Intestinal and splenic T cell responses to enteric Listeria monocytogenes infection: Distinct repertoires of responding CD8 T lymphocytes
57. Localization of distinct Peyer's patch dendritic cell subsets and their recruitment by chemokines macrophage inflammatory protein (MIP) -3 alpha, MIP-3 beta, and secondary lymphoid organ chemokine
58. Regulated MIP-3alpha/CCL20 production by human intestinal epithelium: Mechanism for modulating mucosal immunity
59. Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens
60. The polymeric immunoglobulin receptor (secretory component) mediates transport of immune complexes across epithelial cells: A local defense function for IgA
61. Molecular mechanisms of lymphocyte-mediated cytotoxicity and their role in immunological protection and pathogenesis in vivo
62. Antigen sampling and presentation by epithelial cells in mucosal tissues
63. T cell responses to bacterial infection
64. Generation of mucosal cytotoxic T cells against soluble protein by tissue-specific environmental and costimulatory Signals
65. Induction and visualization of mucosal memory CD8 T cells following systemic virus infection
66. Epithelial M cells: Structure and function
67. Control of homeostasis of CD8(+) memory T cells by opposing cytokines
68. Alpha(4)beta(7) independent pathway for CD8+ T cell-mediated intestinal immunity to rotavirus
69. Lymphocyte CC chemokine receptor 9 and epithelial thymus-expressed chemokine (TECK) expression distinguish the small intestinal immune compartment: Epithelial expression of tissue-specific chemokines as an regional immunity
70. Anatomy of T-cell development in the intestine
71. The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults
72. Gut mucosal immunization with reovirus serotype 1/L stimulates virus-specific cytotoxic T cell precursors as well as IgA memory cells in Peyer's patches
73. Unravelling the mysteries of virulence gene regulation in Salmonella typhimurium
74. Effector and regulatory lymphoid cells and cytokines in mucosal sites
75. A primitive T cell-independent mechanism of intestinal mucosal IgA responses to commensal bacteria
76. IgA production without mu or delta chain expression in developing B cells
77. Structure and function of the intestinal epithelial barrier in health and disease
78. Measuring the diaspora for virus-specific CD8(+) T cells
79. Preferential localization of effector memory cells in non-lymphoid tissue
80. Salmonella typhimurium attachment to human intestinal epithelial monolayers: Transcellular signalling to subepithelial neutrophils
81. Innate immunity
82. Activation of interleukin-1 receptor-associated kinase by gram-negative flagellin
83. Differential expression and regulation of toll-like receptors (TLR) in human leukocytes: Selective expression of TLR3 in dendritic cells
84. Prokaryotic regulation of epithelial responses by inhibition of I kappa B-alpha ubiquitination
85. Collaboration of epithelial cells with organized mucosal lymphoid tissues
86. SopB, a protein required for virulence of Salmonella dublin, is an inositol phosphate phosphatase
87. Expression and regulation of the human beta-defensins hBD-1 and hBD-2 in intestinal epithelium
88. Memory and distribution of virus-specific cytotoxic T lymphocytes (CTLs) and CTL precursors after rotavirus infection
89. Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappa B
90. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
91. Salmonella enteritidis FliC (flagella filament protein) induces human beta-defensin-2 mRNA production by Caco-2 cells
92. The extra domain A of fibronectin activates Toll-like receptor 4
93. Disruption of signaling by Yersinia effector YopJ, a ubiquitin-like protein protease
94. Cytochemical analysis of alkaline phosphatase and esterase activities and of lectin-binding and anionic sites in rat and mouse Peyer's patch M cells
95. The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between Toll-like receptors
96. Cutting edge: A novel chemokine ligand for CCR10 and CCR3 expressed by epithelial cells in mucosal tissues
97. Absence of secretory component expression by epithelial cells overlying rabbit gut-associated lymphoid tissue
98. Organ-specific regulation of the CD8 T cell response to Listeria monocytogenes infection
99. Dendritic cells are early cellular targets of Listeria monocytogenes after intestinal delivery and are involved in bacterial spread in the host
100. Human circulating specific antibody-forming cells after systemic and mucosal immunizations: Differential homing commitments and cell surface differentiation markers
101. Dendritic cells express occludin and claudin, open the tight junctions and sample bacteria preserving epithelial barrier integrity
102. Generation of intestinal T cells from progenitors residing in gut cryptopatches
103. A novel Fc receptor for IgA and IgM is expressed on both hematopoietic and non-hematopoietic tissues
104. Activation of NF-kappaB in intestinal epithelial cells by enteropathogenic Escherichia coli
105. The role of epithelial cells in immune regulation in the gut
106. Migration of intestinal intraepithelial lymphocytes into a polarized epithelial monolayer
107. Fc alpha/mu receptor mediates endocytosis of IgM-coated microbes
108. Flagellin stimulation of intestinal epithelial cells triggers CCL20-mediated migration of dendritic cells
109. Understanding mucosal responsiveness: Lessons from enteric bacterial pathogens
110. Selective expression of liver and activation-regulated chemokine (LARC) in intestinal epithelium in mice and humans
111. CCR6-deficient mice have impaired leukocyte homeostasis and altered contact hypersensitivity and delayed-type hypersensitivity responses
112. Extraintestinal dissemination of Salmonella by CD18-expressing phagocytes
113. Expression of intestine-specific antigen reveals novel pathways of CD8 T cell tolerance induction
114. Regulation of Toll-like receptors in human monocytes and dendritic cells
115. A role for epithelial gamma delta T cells in tissue repair
116. Specificity of the localization of transforming growth factor-alpha immunoreactivity in colon mucosa
117. Transfer of specific cytotoxic T lymphocytes protects mice inoculated with influenza virus