Activation of NF-κB in intestinal epithelial cells by enteropathogenic Escherichia coli

American Journal of Physiology - Cell Physiology

Volumn 273, Issue 4 42-4, 1997, Pages

  Savkovic, Suzana D ^a   Koutsouris, Athanasia ^a   Hecht, Gail ^a,b  

^a UNIVERSITY OF ILLINOIS   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Epithelial immune response; Infectious diarrhea; Inflammation; Interleukin 8; Nuclear factor B

Indexed keywords

ESCHERICHIA COLI LIPOPOLYSACCHARIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; TRANSCRIPTION FACTOR; ENTEROTOXIN; LIPOPOLYSACCHARIDE;

ARTICLE; BACTERIAL INFECTION; CONTROLLED STUDY; ELECTROPHORETIC MOBILITY; ESCHERICHIA COLI; GENE ACTIVATION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; INFLAMMATORY CELL; INTESTINE EPITHELIUM CELL; PRIORITY JOURNAL; BINDING SITE; BIOSYNTHESIS; CELL CULTURE; CELL LINE; CELL MOTION; DRUG EFFECT; GENETICS; IMMUNOLOGY; INTESTINE MUCOSA; KINETICS; METABOLISM; MICROBIOLOGY; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; PROMOTER REGION;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

BASE SEQUENCE; BINDING SITES; CELL LINE; CELL MOVEMENT; ENTEROTOXINS; ESCHERICHIA COLI; HUMANS; INTERLEUKIN-8; INTESTINAL MUCOSA; KINETICS; LIPOPOLYSACCHARIDES; NF-KAPPA B; PROMOTER REGIONS (GENETICS); TUMOR CELLS, CULTURED;

EID: 0031252807     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.1997.273.4.c1160     Document Type: Article

References (16)

1. Baeuerle, P. A. The inducible transcription activator NF-κB: regulation by distinct protein subunits. Biochim. Biophys. Acta 1072: 63-80, 1991.
2. Bielinska, A., R. A. Shivdasani, L. Zhang, G. J. Nabel. Regulation of gene expression with double-stranded phosphorothioate oligonucleotides. Science 250: 997-1000, 1990.
3. Botteri, F. M., K. Ballmer-Hofer, B. Rajput, and Y. Nagamine. Disruption of cytoskeletal structures results in the induction of the urokinase-type plasminogen activator gene expression. J. Biol. Chem. 265: 13327-13334, 1990.
4. Crowe, S. E., L. Alvarez, M. Dytoc, R. H. Hunt, M. Muller, P. Sherman, J. Patel, Y. Jin, and P. B. Ernst. Expression of interleukin-8 and CD54 by human gastric epithelium after Helicobacter pylori infection in vitro. Gastroenterology 108: 65-74, 1995.
5. Donnenberg, M. S., and J. B. Kaper. Enteropathogenic E. coli. Infect. Immun. 60: 3953-3961, 1992.
6. Donnenberg, M. S., J. Yu, and J. B. Kaper. A second chromosomal gene is necessary for intimate attachment of enteropathogenic Escherichia coli to epithelial cells. J. Bacteriol. 175: 4670-4680, 1993.
7. Eck, L., N. D. Perkins, D. P. Carr, and G. J. Nabel. Inhibition of phorbol ester-induced cellular adhesion by competitive binding of NF-κB in vivo. Mol. Cell. Biol. 13: 6530-6536, 1993.
8. Foubister, V., I. Rosenshine, M. S. Donnenberg, and B. B. Finlay. The eaeB gene of enteropathogenic E. coli is necessary for signal transduction in epithelial cells. Infect. Immun. 62: 3038-3040, 1994.
9. Foubister, V., I. Rosenshine, and B. B. Finlay. A diarrheal pathogen, enteropathogenic Escherichia coli (EPEC), triggers a flux of inositol phosphates in infected epithelial cells. J. Exp. Med. 179: 993-998, 1994.
10. Girón, J. A., A. S. Y. Ho, and G. K. Schoolnik. An inducible bundle-forming pilus of enteropathogenic Escherichia coli. Science 254: 710-713, 1991.
11. Hoch, R. C., I. U. Schraufstätter, and C. G. Cochrane. In vivo, in vitro, and molecular aspects of interleukin-8 and the interleukin-8 receptors. J. Lab. Clin. Med. 128: 134-145, 1996.
12. Ishikawa, Y., N. Mukaida, K. Kuno, N. Rice, S. Okamoto, and K. Matsushima. Establishment of lipopolysaccharide-dependent nuclear factor κB activation in a cell-free system. J. Biol. Chem. 270: 4158-4164, 1995.
13. Jarvis, K. G., J. A. Girón, A. E. Jerse, T. K. McDaniel, M. S. Donnenberg, and J. B. Kaper. Enteropathogenic Escherichia coli contains a putative type III secretion system necessary for the export of proteins involved in attaching and effacing lesion formation. Proc. Natl. Acad. Sci. USA 92: 7996-8000, 1995.
14. Jerse, A. E., and J. B. Kaper. The eae gene of enteropathogenic Escherichia coli encodes a 94-kilodalton membrane protein, the expression of which is influenced by the EAF plasmid. Infect. Immun. 59: 4302-4309, 1991.
15. Jerse, A. E., J. Yu, B. D. Tall, and J. B. Kaper. A genetic locus of enteropathogenic Escherichia coli necessary for the production of attaching and effacing lesions on tissue culture cells. Proc. Natl. Acad. Sci. USA 87: 7839-7843, 1990.
16. Jung, H. C., C. L. Eckmann, S. Yang, A. Panja, E. Fierer, Morzycka-Wroblewska, and M. F. Kagnoff. A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion. J. Clin. Invest. 95: 55-65.