Extraintestinal dissemination of Salmonella by CD18-expressing phagocytes

Nature

Volumn 401, Issue 6755, 1999, Pages 804-808

  Vazquez Terres, Andrés ^a   Jones Carson, Jessica ^b   Bäumler, Andreas J ^c   Falkow, Stanley ^d   Valdivia, Raphael ^d,g   Brown, William ^a,e   Lo, Mysan ^a,e   Berggren, Ruth ^a,h   Parks, W Tony ^f   Fang, Ferric C ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

^c TEXAS A AND M UNIVERSITY   (United States)

^d STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e VETERANS AFFAIRS MEDICAL CENTER   (United States)

^f NATIONAL CANCER INSTITUTE   (United States)

^g UNIVERSITY OF CALIFORNIA   (United States)

^h UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD18 ANTIGEN; IMMUNOGLOBULIN A;

ANIMAL EXPERIMENT; ANTIGEN EXPRESSION; ARTICLE; CELL INVASION; IMMUNE RESPONSE; INTESTINE CELL; MOUSE; NONHUMAN; PATHOGENICITY; PHAGOCYTE; PRIORITY JOURNAL; SALMONELLA TYPHIMURIUM; SALMONELLOSIS;

3-PHOSPHOSHIKIMATE 1-CARBOXYVINYLTRANSFERASE; ALKYL AND ARYL TRANSFERASES; ANIMALS; ANTIGENS, CD18; BACTEREMIA; BACTERIAL PROTEINS; BIOLOGICAL TRANSPORT; FIMBRIAE, BACTERIAL; GENES, BACTERIAL; IMMUNITY, MUCOSAL; INTESTINES; MICE; MICE, INBRED C57BL; MUTAGENESIS; PHAGOCYTES; SALMONELLA INFECTIONS, ANIMAL; SALMONELLA TYPHIMURIUM;

ANIMALIA; MYCOBACTERIUM; MYCOBACTERIUM BOVIS; NEGIBACTERIA; ORTHOREOVIRUS; SALMONELLA; SALMONELLA TYPHIMURIUM; SHIGELLA FLEXNERI; TYPHIMURIUM; YERSINIA ENTEROCOLITICA;

EID: 0033592595     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/44593     Document Type: Article

References (29)

1. Wolf, J. L. et al. Intestinal M cells: a pathway for entry of reovirus into the host. Science 212, 471-472 (1981).
2. Wassef, J. S., Keren, D. F. & Mailloux, J. I. Role of M cells in initial antigen uptake and in ulcer formation in the rabbit intestinal loop model of shigellosis. Infect. Immun. 57, 858-863 (1989).
3. Jones, B. D., Ghori, N. & Falkow, S. Salmonella typhimurium initiates murine infection by penetrating and destroying the specialized epithelial M cells of the Peyer's patches. J. Exp. Med. 180, 15-23 (1994).
4. Neutra, M. R., Frey, A. & Krachenguhl, J. P. Epithelial M cells: gateways for mucosal infection and immunization. Cell 86, 345-348 (1996).
5. Galan, J. E. & Curtiss, R. III. Cloning and molecular characterization of genes whose products allow Salmonella typhimurium to penetrate tissue culture cells. Proc. Natl Acad. Sci. USA 86, 6383-6387 (1989).
6. Lee, C. A., Jones, B. D. & Falkow, S. Identification of a Salmonella typhimurium invasion locus by selection for hyperinvasive mutants. Proc. Natl Acad. Sci. USA 89, 1847-1851 (1992).
7. Francis, C. L., Ryan, T. A., Jones, B. D., Smith, S. J. & Falkow, S. Ruffles induced by Salmonella and other stimuli direct macropinocytosis of bacteria. Nature 364, 639-642 (1993).
8. Collazo, C. M. & Galan, J. E. The invasion-associated type III protein secretion system in Salmonella - a review. Gene 192, 51-59 (1997).
9. Pehheiter, K. L., Mathur, N., Giles, D., Gahlen, T. & Jones, B. D. Non-invasive Salmonella typhimurium mutants are avirulent because of an inability to enter and destroy M cells of ileal Peyer's patches. Mol. Microbiol. 24, 697-709 (1997).
10. Baumler, A. J., Tsolis, R. M., Valentine, P. J., Ficht, T. A. & Heffron, F. Synergistic effect of mutations in invA and lpfC on the ability of Salmonella typhimurium to cause murine typhoid. Infect. Immun. 65, 2254-2259 (1997).
11. Shang, X. Z. & Issekutz, A. C. Contribution of CD11a/CD18, CD11b/CD18, ICAM-1 (CD54) and -2 (CD102) to human monocyte migration through endothelium and connective tissue fibroblast barriers. Eur. J. Immunol. 28, 1070-1979 (1998).
12. Fields, P. I., Swanson, R. V., Haidaris, T. G. & Heffron, F. Mutants of Salmonella typhimurium that cannot survive within the macrophage are avirulent. Proc. Natl Acad. Sci. USA 83, 5189-5193 (1986).
13. Wilson, R. W. et al. Gene targeting yields a CD18-mutant mouse for study of inflammation. J. Immunol 151, 1571-1578 (1993).
14. Kishimoto, T. K. & Anderson, D. C. in Inflammation: Basic Principles and Clinical Correlates 2nd edn (eds Gallin, J. I., Goldstein, I. M. & Snyderman, R.) 353-406 (Raven, New York, 1992).
15. Conlan, J. W. & North, R. J. Listeria monocytogenes, but not Salmonella typhimurium, elicits a CD18-independent mechanism of neutrophil extravasation into the murine peritoneal cavity. Infect. Immun. 62, 2702-2706 (1994).
16. Baumler, A. J., Tsolis, R. M. & Heffron, F. The lpf fimbrial operon mediates adhesion to murine Peyer's patches. Proc. Natl Acad. Sci. USA 93, 279-283 (1996).
17. Gerichter, C. B. The dissemination of Salmonella typhi, S. paratyphi A and S. paratyphi B through the organs of the white mouse by oral infection. J. Hyg. 58, 307-319 (1960).
18. Bernstein, C. N., Sargent, M., Gallatin, W. M. & Wilkins, J. β2-integrin/intercellular adhesion molecule (ICAM) expression in the normal human intestine. Clin. Exp. Immunol. 106, 160-169 (1996).
19. Oskoui, R., Davis, W. & Gomes, M. N. Salmonella aortitis. A report of a successfully treated case with a comprehensive review of the literature. Arch. Int. Med. 153, 517-525 (1993).
20. Neutra, M. R. Current concepts in mucosal immunity. V. Role of M cells in transepithelial transport of antigens and pathogens to the mucosal immune system. Am. J. Physiol. 274, G785-791 (1998).
21. Autenrieth, I. B., Kempf, V., Sprinz, T., Preger, S. & Schnell, A. Defense mechanisms in Peyer's patches and mesenteric lymph nodes against Yersinia enterocolitica involve integrins and cytokines. Infect. Immun. 64, 1357-1368 (1996).
22. Tsolis, R. M., Bauler, A. J., Stojiljkovic, I. & Heffron, F. Fur regulon of Salmonella typhimurium: identification of new iron-regulated genes. J. Bacteriol. 177, 4628-4637 (1995).
23. Valdivia, R. H. & Falkow, S. Bacterial genetics by flow cytometry: rapid isolation of Salmonella typhimurium acid-inducible promoters by differential fluorescence induction. Mol. Microbiol. 22, 367-378 (1996).
24. Rahn, K. et al. Amplification of an invA gene sequence of Salmonella typhimurium by polymerase chain reaction as a specific method of detection of Salmonella. Mol. Cell. Probes 6, 271-279 (1992).
25. Kinder, S. A., Badger, J. L., Bryant, G. O., Pepe, J. C. & Miller, V. L. Cloning of the YenI restriction endonuclease and methyltransferase from Yersinia enterocolitica serotype O:8 and construction of a transformable R-M+ mutant Gene 136, 271-275 (1993).
26. Miller, V. L. & Mekalanos, J. J. A novel suicide vector and its use in construction of insertion mutations; osmoregulation of outer membrane proteins and virulence determinants requires toxR. J. Bacteriol. 170, 2575-2583 (1988).
27. Stojiljkovic, I., Baumler, A. J. & Heffron, F. Ethanolamine utilization operon of Salmonella typhimurium: nucleotide sequence, protein expression and mutational analysis of the cchB eutE eutJ eutG eutH gene cluster. J. Bacteriol. 177, 1357-1366 (1995).
28. Valentine, P. J., Devore, B. P. & Heffron, F. Identification of three highly attenuated Salmonella typhimurium mutants that are more immunogenic and protective in mice than a prototypical aroA mutant. Infect. Immun. 66, 3378-3383 (1998).
29. Berggren, R. E. et al. HIV gp120-specific cell-mediated immune responses in mice after oral immunization with recombinant Salmonella. J. AIDS 10, 489-495 (1995).