α4β7 independent pathway for CD8+ T cell-mediated intestinal immunity to rotavirus

Journal of Clinical Investigation

Volumn 106, Issue 12, 2000, Pages 1541-1552

  Kuklin, N A ^a   Rott, L ^a   Darling, J ^a   Campbell, J J ^a   Franco, M ^a   Feng, N ^a   Muller W ^a   Wagner, N ^a   Altman, J ^a   Butcher, E C ^a   Greenberg, H B ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA4 INTEGRIN; BETA7 INTEGRIN; CD8 ANTIGEN; INTEGRIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; IMMUNOREGULATION; INTESTINE MUCOSA; MOUSE; NONHUMAN; PRIORITY JOURNAL; ROTAVIRUS; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; VIRUS RESISTANCE;

EID: 0034518435     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI10927     Document Type: Article

References (37)

1. Immunological memory and protective immunity: Understanding their relation
2. Immunization against virus disease
3. Lymphocyte trafficking and regional immunity
4. The immunology of rotavirus infection in the mouse
5. Identification of a murine Peyer's patch: Specific lymphocyte homing receptor as an integrin molecule with an alpha chain homologous to human VLA-4 alpha
6. Role of alpha 4-integrins in lymphocyte homing to mucosal tissues in vivo
7. Homing of naive and memory T lymphocyte subsets to Peyer's patches, lymph nodes, and spleen
8. Expression of the mucosal homing receptor alpha4beta7 correlates with the ability of CD8+ memory T cells to clear rotavirus infection
9. Critical role for beta7 integrins in formation of the gut-associated lymphoid tissue
10. Efficient lymphocyte migration across high endothelial venules of mouse Peyer's patches requires overlapping expression of L-selectin and beta7 integrin
11. L-selectin and beta7 integrin synergistically mediate lymphocyte migration to mesenteric lymph nodes
12. The roles of L-selectin, beta 7 integrins, and P-selectin in leukocyte rolling and adhesion in high endothelial venules of Peyer's patches
13. The role of beta7 integrins in CD8 T cell trafficking during an antiviral immune response
14. Adhesion between epithelial cells and T lymphocytes mediated by E-cadherin and the alpha E beta 7 integrin
15. Analyses of homologous rotavirus infection in the mouse model
16. Serotypic similarity and diversity of rotaviruses of mammalian and avian origin as studied by plaque-reduction neutralization
17. Psoralen preparation of antigenically intact noninfectious rotavirus particles
18. Response of mice to rotaviruses of bovine or primate origin assessed by radioimmunoassay, radioimmunoprecipitation, and plaque reduction neutralization
19. Induction of mucosal immunity against herpes simplex virus by plasmid DNA immunization
20. Direct fluorescent labeling of cells with fluorescein or rhodamine isothiocyanate. I. Technical aspects
21. Novel function for intestinal intraepithelial lymphocytes. Murine CD3+, gamma/delta TCR+ T cells produce IFN-gamma and IL-5
22. Role of B cells and cytotoxic T lymphocytes in clearance of and immunity to rotavirus infection in mice
23. Immunomodulation by mucosal gene transfer using TGF-beta DNA
24. Soluble proteins delivered to dendritic cells via pH-sensitive liposomes induce primary cytotoxic T lymphocyte responses in vitro
25. Phenotypic analysis of antigen-specific T lymphocytes
26. An immunodominant cytotoxic T cell epitope on the VP7 rotavirus protein overlaps the H2 signal peptide
27. HLA-A2-peptide complexes: Refolding and crystallization of molecules expressed in Escherichia coli and complexed with single antigenic peptides
28. CD8+ T cells can mediate almost complete short-term and partial long-term immunity to rotavirus in mice
29. Recovery from chronic rotavirus infection in mice with severe combined immunodeficiency: Virus clearance mediated by adoptive transfer of immune CD8+ T lymphocytes
30. Distinct roles of L-selectin and integrins alpha 4 beta 7 and LFA-1 in lymphocyte homing to Peyer's patch-HEV in situ: The multistep model confirmed and refined
31. Monoclonal antibodies specific for beta 7 integrin and mucosal addressin cell adhesion molecule-1 (MAdCAM-1) reduce inflammation in the colon of scid mice reconstituted with CD45RBhigh CD4+ T cells
32. Beta2 integrins and ICAM-1 are involved in establishment of the intestinal mucosal T cell compartment
33. Lymphocyte homing and homeostasis
34. The epithelial cell response to rotavirus infection
35. Cutting edge: Identification of the orphan chemokine receptor GPR-9-6 as CCR9, the receptor for the chemokine TECK
36. Expression of mucosal homing receptor alpha4beta7 by circulating CD4+ cells with memory for intestinal rotavirus
37. The memory B cell subset responsible for the secretory IgA response and protective humoral immunity to rotavirus expresses the intestinal homing receptor, alpha4beta7