Fas receptor and neuronal cell death after spinal cord ischemia

Journal of Neuroscience

Volumn 20, Issue 18, 2000, Pages 6879-6887

  Matsushita, Kohji ^a   Wu, Yongqin ^a   Qiu, Jianhua ^a   Lang Lazdunski, Loic ^a   Hirt, Lorenz ^a   Waeber, Christian ^a   Hyman, Bradley T ^a   Yuan, Junying ^a   Moskowitz, Michael A ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Caspase 3; Caspase 8; Cell death; DISC; Fas; Spinal cord ischemia

Indexed keywords

CASPASE; CYTOCHROME C OXIDASE; DNA; FAS ANTIGEN; GELSOLIN; MESSENGER RNA; NUCLEOTIDE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVATION; FEMALE; IMMUNOPRECIPITATION; IN SITU HYBRIDIZATION; MALE; MOUSE; NERVE CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPINAL CORD ISCHEMIA;

EID: 0034666285     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.20-18-06879.2000     Document Type: Article

References (53)

1. Abberant transcription caused by the insertion of an early transposable element in an intron of the Fas antigen gene of lpr mice
2. FasL (CD95L, Apo1L) is expressed in the normal rat and human brain: Evidence for the exsistence of an immunological brain barrier
3. Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1-and TNF receptor-induced cell death
4. Mitochondrial cytochrome c release in apoptosis occurs upstream of DEV D-specific caspase activation and independently of mitochondrial transmembrane depolarization
5. Fas/Apo [Apoptosis]-1 and associated proteins in the differentiating cerebral cortex: Induction of caspase-dependent cell death and activation of NF-κB
6. Induction of caspase-3-like protease may mediate delayed neuronal death in the hippocampus after transient cerebral ischemia
7. Spinal cord infarction: Etiology and outcome
8. Apoptosis and delayed degeneration after spinal cord injury in rats and monkeys
9. Attenuation of delayed neuronal death after mild focal ischemia in mice by inhibition of the caspase family
10. Partial ATP depletion induces Fas- and caspase-mediated apoptosis in MDCK cells
11. Fas/CD95/APO-1 can function as a death receptor for neuronal cells in vitro and in vivo and is upregulated following cerebral hypoxic-ischemic injury to the developing rat brain
12. In vitro activation Of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains
13. Differential regulation and ATP requirement for caspase-8 and caspase-3 activation during CD95- and anticancer drug-induced apoptosis
14. Prolonged therapeutic window for ischemic brain damage caused by delayed caspase activation
15. Neuronal necrosis after middle cerebral artery occlusion in Wistar rats progresses at different time intervals in the caudoputamen and the cortex
16. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
17. Inhibition of interleukin 1-converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage
18. Apoptosis of motor neurons with induction of caspases in the spinal cord after ischemia
19. Protection of rat spinal cord from ischemia with dextrorphan and cycloheximide: Effects on necrosis and apoptosis
20. Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor
21. Caspase-3-generated fragment of gelsolin: Effector of morphological change in apoptosis
22. Spinal cord ischemic injury: Is it preventable?
23. Release of caspase-9 from mitochondria during neuronal apoptosis and cerebral ischemia
24. Decreased apoptosis in the brain and premature lethality in CPP-32 deficient mice
25. Apoptosis induction by caspase-8 is amplified through the mitochondrial release of cytochrome c
26. Spinal cord ischemia: Development of a model in the mouse
27. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
28. Neuronal and glial apoptosis after traumatic spinal cord injury
29. Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis
30. Cell death suggestive of apoptosis after spinal cord ischemia in rabbits
31. CD95 ligand (Fas-L/APO-1L) and tumor necrosis factor-related apoptosis-inducing ligand mediate ischemia-induced apoptosis in neurons
32. Localization of Fas antigen mRNA induced in postischemic murine forebrain by in situ hybridization
33. FLICE is activated by association with the CD95 death-inducing signaling complex (DISC)
34. FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex
35. Apoptosis by death receptor
36. The Fas receptor
37. Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia
38. Programmed cell death of embryonic motoneurons triggered through the Fas death receptor
39. Molecular cloning and char- acterization of mouse caspase-8
40. Delayed and selective motor neuron death after transient spinal cord ischemia: A role of apoptosis?
41. Two CD95 (APO1/Fas) signaling pathways
42. Ordering the cytochrome c-initiated caspase cascade: Hierarchial activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner
43. Activation of the caspase-3 apoptotic cascade in traumatic spinal cord injury
44. In situ immunodetection of activated caspase-3 in apoptotic neurons in the developing nervous system
45. Molecular ordering of the Fas-apoptotic pathway: The Fas/APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases
46. Pro-caspase-3 is a major physiologic target of caspase-8
47. Death by a thousand cuts: An ever increasing list of caspase substrates
48. Microscale autoradiographic method for the qualitative and quantitative analysis of apoptotic DNA fragmentation
49. Caspase-8 and caspase-3 are expressed by different populations of cortical neurons undergoing delayed cell death after focal stroke in the rat
50. Oxidative stress and hypoxia-reoxygenation trigger CD95 (APO-1/Fas) ligand expression in microglial cells
51. Traumatic aortic rupture: Twenty-year meta-analysis of mortality and risk of paraplegia
52. In vivo evidence that caspase-3 is required for Fas-mediated apoptosis of hepatocytes
53. Bid-deficient mice are resistent to Fas-induced hepatocellular apoptosis