-
1
-
-
2042437650
-
Initial sequencing and analysis of the human genome
-
International Human Genome Sequencing Consortium
-
(2001)
Nature
, vol.409
, pp. 860-921
-
-
-
2
-
-
0035895505
-
The sequence of the human genome
-
(2001)
Science
, vol.291
, pp. 1304-1351
-
-
Venter, J.C.1
Adams, M.D.2
Myers, E.W.3
Li, P.W.4
Mural, R.J.5
Sutton, G.G.6
Smith, H.O.7
Yandell, M.8
Evans, C.A.9
Holt, R.A.10
-
7
-
-
0034677755
-
Mechanism-based target identification and drug discovery in cancer research
-
(2000)
Science
, vol.287
, pp. 1969-1973
-
-
Gibbs, J.B.1
-
12
-
-
0035818885
-
Discovery of small molecule inhibitors of Bcl-2 through structure based computer screening
-
(2001)
J. Med. Chem
, vol.44
, pp. 4313-4324
-
-
Enyedy, I.J.1
Ling, Y.2
Nacro, K.3
Tomita, Y.4
Wu, X.5
Cao, Y.6
Guo, R.7
Li, B.8
Zhu, X.9
Huang, Y.10
Long, Y.Q.11
Roller, P.P.12
Yang, D.13
Wang, S.14
-
13
-
-
0005364689
-
-
The Times, 9 March
-
(2002)
, pp. 8
-
-
-
17
-
-
0037116617
-
Cell based assays for identification of novel double strand break inducing agents
-
(2002)
J. Natl. Cancer Inst
, vol.94
, pp. 88-94
-
-
Dunstan, H.M.1
Ludlow, C.2
Goehle, S.3
Cronk, M.4
Szanski, P.5
Evans, D.R.H.6
Simon, J.A.7
Lamb, J.R.8
-
26
-
-
0032893263
-
SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularisation, and growth of multiple tumor types
-
(1999)
Cancer Res
, vol.59
, pp. 99-106
-
-
Fong, T.A.T.1
Shawver, L.K.2
Sun, L.3
Tang, C.4
App, H.5
Powell, J.6
Kim, Y.H.7
Schreck, R.8
Wang, X.9
Risau, W.10
Ullrich, A.11
Hirth, K.P.12
McMahon, G.13
-
30
-
-
0032984348
-
Blockade of the MAP kinase pathway suppresses growth of colon tumours in vivo
-
(1999)
Nat. Med
, vol.5
, pp. 810-815
-
-
Sebolt-Leopold, J.S.1
Dudley, D.T.2
Herrerra, R.3
Van Becelaere, K.4
Willand, A.5
Gowan, R.C.6
Tecle, H.7
Barrett, S.D.8
Bridges, A.9
Przybranowski, S.10
Leopold, W.R.11
Saltiel, A.R.12
-
31
-
-
14444279192
-
Identification of a novel inhibitor of mitogen-activated protein kinase
-
(1998)
J. Biol. Chem
, vol.29
, pp. 18623-18632
-
-
Favata, M.F.1
Kurumi, Y.H.2
Manos, E.J.3
Daulerio, A.J.4
Stradley, D.A.5
Feeser, W.S.6
Van Dyk, D.E.7
Pitts, W.J.8
Earl, R.A.9
Hobbs, F.10
Copeland, R.A.11
Magolda, R.L.12
Scherle, P.A.13
Trzaskos, J.M.14
-
35
-
-
0033551066
-
Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 4325-4329
-
-
Chen, Y.N.1
Sharma, S.K.2
Ramsey, T.M.3
Jiang, L.4
Martin, M.S.5
Baker, K.6
Adams, P.D.7
Bair, K.W.8
Kaelin W.G., Jr.9
-
37
-
-
0035890610
-
Radiosensitisation of mutant cells by PD0166285, a novel G2 checkpoint abrogator
-
(2001)
Cancer Res
, vol.61
, pp. 8211-8217
-
-
Wang, Y.1
Li, J.2
Booher, R.N.3
Kraker, A.4
Lawrence, T.5
Leopold, W.R.6
Sun, Y.7
-
39
-
-
0035884377
-
Inhibition of tumour cell invasion and angiogenesis by motuporamines
-
(2001)
Cancer Res
, vol.61
, pp. 6788-6794
-
-
Roskelley, C.D.1
Williams, D.E.2
McHardy, L.M.3
Leong, K.G.4
Troussard, A.5
Karsan, A.6
Andersen, R.J.7
Dedhar, S.8
Roberge, M.9
-
44
-
-
0035925072
-
Levels of hypoxia-inducible factor-1 alpha during breast carcinogenesis
-
(2001)
J. Natl. Cancer Inst
, vol.93
, pp. 1175-1177
-
-
Bos, R.1
Zhong, H.2
Hanrahan, C.F.3
Mommers, E.C.4
Semenza, G.L.5
Pinedo, H.M.6
Abeloff, M.D.7
Simons, J.W.8
van Driest, P.J.9
van der Wall, E.10
-
47
-
-
0035499141
-
High throughput screening for identification of small molecule inhibitors of histone acetyltransferases using scintillating microplates (flashplate)
-
(2001)
Anal. Biochem
, vol.298
, pp. 62-68
-
-
Turlais, F.1
Hardcastle, A.2
Rowlands, M.3
Newbatt, Y.4
Bannister, A.5
Kouzarides, T.6
Workman, P.7
Aherne, G.W.8
-
48
-
-
0035721813
-
Update on Her-2 as a target for cancer therapy: Herceptin in the clinical setting
-
(2001)
Breast Cancer Res
, vol.3
, pp. 380-384
-
-
Miles, D.W.1
-
49
-
-
0035181479
-
Preclinical antitumour activity and pharmacodynamic studies with the farnesyl protein transferase inhibitor R115777 in human breast cancer
-
(2001)
Clin. Cancer Res
, vol.7
, pp. 3544-3550
-
-
Kelland, L.R.1
Smith, V.2
Valenti, M.3
Patterson, L.4
Clarke, P.A.5
Detre, S.6
End, H.7
Howes, A.J.8
Dowsett, M.9
Workman, P.10
Johnston, S.R.11
-
50
-
-
0035240617
-
Farnesyl transferase inhibitors - A novel targeted therapy for breast cancer
-
(2000)
Lancet Oncol
, vol.2
, pp. 18-26
-
-
Johnston, S.R.D.1
|