Radiosensitization of p53 mutant cells by PD0166285, a novel G2 checkpoint abrogator

Cancer Research

Volumn 61, Issue 22, 2001, Pages 8211-8217

  Wang, Y ^a   Li, J ^a   Booher, R N ^a   Kraker, A ^a   Lawrence, T ^a   Leopold, W R ^a   Sun, Y ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

7 HYDROXYSTAUROSPORINE; CAFFEINE; PD 0166285; PROTEIN KINASE; PROTEIN P53; RADIOSENSITIZING AGENT; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BINDING SITE; CELL CYCLE G2 PHASE; CELL KILLING; CELL MUTANT; DNA DAMAGE; DNA REPAIR; HUMAN; HUMAN CELL; MITOSIS; MITOSIS INDEX; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RECEPTOR DOWN REGULATION; TARGET CELL;

ANIMALS; CDC2 PROTEIN KINASE; CELL CYCLE PROTEINS; CELL DEATH; DNA DAMAGE; ENZYME INHIBITORS; G2 PHASE; HELA CELLS; HT29 CELLS; HUMANS; MICE; MUTATION; NUCLEAR PROTEINS; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; PYRIMIDINES; RADIATION-SENSITIZING AGENTS; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0035890610     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

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3. Human Weel kinase inhibits cell division by phosphorylating p 34cdc2 exclusively on Tyrl5
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