메뉴 건너뛰기




Volumn 20, Issue 11, 2000, Pages 3928-3941

Neoplastic transformation by Notch requires nuclear localization

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE PROTEIN;

EID: 0034024625     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.20.11.3928-3941.2000     Document Type: Article
Times cited : (103)

References (94)
  • 1
    • 0029143840 scopus 로고
    • Involvement of Notch-1 in mammalian retinal neurogenesis: Association of Notch-1 activity with both immature and terminally differentiated cells
    • Ahmad, I., P. Zagouras, and S. Artavanis-Tsakonas. 1995. Involvement of Notch-1 in mammalian retinal neurogenesis: association of Notch-1 activity with both immature and terminally differentiated cells. Mech. Dev. 53:73-85.
    • (1995) Mech. Dev. , vol.53 , pp. 73-85
    • Ahmad, I.1    Zagouras, P.2    Artavanis-Tsakonas, S.3
  • 2
    • 0033617522 scopus 로고    scopus 로고
    • Notch signaling: Cell fate control and signal integration in development
    • Artavanis-Tsakonas, S., M. D. Rand, and R. J. Lake. 1999. Notch signaling: cell fate control and signal integration in development. Science 284:770-776.
    • (1999) Science , vol.284 , pp. 770-776
    • Artavanis-Tsakonas, S.1    Rand, M.D.2    Lake, R.J.3
  • 4
    • 0030945447 scopus 로고    scopus 로고
    • Oncogenic forms of NOTCH1 lacking either the primary binding site for RBP-Jkappa or nuclear localization sequences retain the ability to associate with RBP-Jkappa and activate transcription
    • Aster, J. C., E. S. Robertson, R. P. Hasserjian, J. R. Turner, E. Kieff, and J. Sklar. 1997. Oncogenic forms of NOTCH1 lacking either the primary binding site for RBP-Jkappa or nuclear localization sequences retain the ability to associate with RBP-Jkappa and activate transcription. J. Biol. Chem. 272:11336-11343.
    • (1997) J. Biol. Chem. , vol.272 , pp. 11336-11343
    • Aster, J.C.1    Robertson, E.S.2    Hasserjian, R.P.3    Turner, J.R.4    Kieff, E.5    Sklar, J.6
  • 5
    • 0029670476 scopus 로고    scopus 로고
    • Interaction between Wingless and Notch signaling pathways mediated by dishevelled
    • Axelrod, J. D., K. Matsuno, S. Artavanis-Tsakonas, and N. Perrimon. 1996. Interaction between Wingless and Notch signaling pathways mediated by dishevelled. Science 271:1826-1832.
    • (1996) Science , vol.271 , pp. 1826-1832
    • Axelrod, J.D.1    Matsuno, K.2    Artavanis-Tsakonas, S.3    Perrimon, N.4
  • 6
    • 0029023204 scopus 로고
    • Transient and restricted expression during mouse embryo-genesis of Dll1, a murine gene closely related to Drosophila Delta
    • Bettenhausen, B., M. Hrabe de Angelis, D. Simon, J. L. Guenet, and A. Gossler. 1995. Transient and restricted expression during mouse embryo-genesis of Dll1, a murine gene closely related to Drosophila Delta. Development 121:2407-2418.
    • (1995) Development , vol.121 , pp. 2407-2418
    • Bettenhausen, B.1    Hrabe De Angelis, M.2    Simon, D.3    Guenet, J.L.4    Gossler, A.5
  • 7
    • 0031899677 scopus 로고    scopus 로고
    • Notch1 and Notch2 inhibit myeloid differentiation in response to different cytokines
    • Bigas, A., D. I. Martin, and L. A. Milner. 1998. Notch1 and Notch2 inhibit myeloid differentiation in response to different cytokines. Mol. Cell. Biol. 18:2324-2333.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 2324-2333
    • Bigas, A.1    Martin, D.I.2    Milner, L.A.3
  • 9
    • 0032904239 scopus 로고    scopus 로고
    • Notch1-induced delay of human hematopoietic progenitor cell differentiation is associated with altered cell cycle kinetics
    • Carlesso, N., J. C. Aster, J. Sklar, and D. T. Scadden. 1999. Notch1-induced delay of human hematopoietic progenitor cell differentiation is associated with altered cell cycle kinetics. Blood 93:838-848.
    • (1999) Blood , vol.93 , pp. 838-848
    • Carlesso, N.1    Aster, J.C.2    Sklar, J.3    Scadden, D.T.4
  • 10
    • 0030910099 scopus 로고    scopus 로고
    • Regulation of the ERBB-2 promoter by RBPJkappa and NOTCH
    • Chen, Y., W. H. Fischer, and G. N. Gill. 1997. Regulation of the ERBB-2 promoter by RBPJkappa and NOTCH. J. Biol. Chem. 272:14110-14114.
    • (1997) J. Biol. Chem. , vol.272 , pp. 14110-14114
    • Chen, Y.1    Fischer, W.H.2    Gill, G.N.3
  • 11
    • 0027412543 scopus 로고
    • Cloning, analysis, and chromosomal localization of Notch-1, a mouse homolog of Drosophila Notch
    • del Amo, F. F., M. Gendron-Maguire, P. J. Swiatek, N. A. Jenkins, N. G. Copeland, and T. Gridley. 1993. Cloning, analysis, and chromosomal localization of Notch-1, a mouse homolog of Drosophila Notch. Genomics 15: 259-264.
    • (1993) Genomics , vol.15 , pp. 259-264
    • Del Amo, F.F.1    Gendron-Maguire, M.2    Swiatek, P.J.3    Jenkins, N.A.4    Copeland, N.G.5    Gridley, T.6
  • 12
    • 0026670590 scopus 로고
    • Expression pattern of Motch, a mouse homolog of Drosophila Notch, suggests an important role in early postimplantation mouse development
    • Del Amo, F. F., D. E. Smith, P. J. Swiatek, M. Gendron-Maguire, R. J. Greenspan, A. P. McMahon, and T. Gridley. 1992. Expression pattern of Motch, a mouse homolog of Drosophila Notch, suggests an important role in early postimplantation mouse development. Development 115:737-744.
    • (1992) Development , vol.115 , pp. 737-744
    • Del Amo, F.F.1    Smith, D.E.2    Swiatek, P.J.3    Gendron-Maguire, M.4    Greenspan, R.J.5    McMahon, A.P.6    Gridley, T.7
  • 13
    • 0028293148 scopus 로고
    • Cytosolic interaction between deltex and Notch ankyrin repeats implicates deltex in the Notch signaling pathway
    • Diederich, R. J., K. Matsuno, H. Hing, and S. Artavanis-Tsakonas. 1994. Cytosolic interaction between deltex and Notch ankyrin repeats implicates deltex in the Notch signaling pathway. Development 120:473-481.
    • (1994) Development , vol.120 , pp. 473-481
    • Diederich, R.J.1    Matsuno, K.2    Hing, H.3    Artavanis-Tsakonas, S.4
  • 14
    • 0033613401 scopus 로고    scopus 로고
    • Involvement of notch1 in the development of mouse mammary tumors
    • Dievart, A., N. Beaulieu, and P. Jolicoeur. 1999. Involvement of notch1 in the development of mouse mammary tumors. Oncogene 18:5973-5981.
    • (1999) Oncogene , vol.18 , pp. 5973-5981
    • Dievart, A.1    Beaulieu, N.2    Jolicoeur, P.3
  • 15
    • 0028345891 scopus 로고
    • The recombination signal sequence-binding protein RBP-2N functions as a transcriptional repressor
    • Dou, S., X. Zeng, P. Cortes, H. Erdjument-Bromage, P. Tempst, T. Honjo, and L. D. Vales. 1994. The recombination signal sequence-binding protein RBP-2N functions as a transcriptional repressor. Mol. Cell. Biol. 14:3310-3319.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 3310-3319
    • Dou, S.1    Zeng, X.2    Cortes, P.3    Erdjument-Bromage, H.4    Tempst, P.5    Honjo, T.6    Vales, L.D.7
  • 16
    • 0032825496 scopus 로고    scopus 로고
    • The Net repressor is regulated by nuclear export in response to anisomycin, UV, and heat shock
    • Ducret, C., S. M. Maira, A. Dierich, and B. Wasylyk. 1999. The Net repressor is regulated by nuclear export in response to anisomycin, UV, and heat shock. Mol. Cell. Biol. 19:7076-7087.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 7076-7087
    • Ducret, C.1    Maira, S.M.2    Dierich, A.3    Wasylyk, B.4
  • 17
    • 0025856717 scopus 로고
    • TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms
    • Ellisen, L. W., J. Bird, D. C. West, A. L. Soreng, T. C. Reynolds, S. D. Smith, and J. Sklar. 1991. TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms. Cell 66:649-661.
    • (1991) Cell , vol.66 , pp. 649-661
    • Ellisen, L.W.1    Bird, J.2    West, D.C.3    Soreng, A.L.4    Reynolds, T.C.5    Smith, S.D.6    Sklar, J.7
  • 18
    • 0025849162 scopus 로고
    • Complex cellular and subcellular regulation of notch expression during embryonic and imaginal development of Drosophila: Implications for notch function
    • Fehon, R. G., K. Johansen, I. Rebay, and S. Artavanis-Tsakonas. 1991. Complex cellular and subcellular regulation of notch expression during embryonic and imaginal development of Drosophila: implications for notch function. J. Cell Biol. 113:657-669.
    • (1991) J. Cell Biol. , vol.113 , pp. 657-669
    • Fehon, R.G.1    Johansen, K.2    Rebay, I.3    Artavanis-Tsakonas, S.4
  • 19
    • 0028171718 scopus 로고
    • The suppressor of hairless protein participates in notch receptor signaling
    • Fortini, M. E., and S. Artavanis-Tsakonas. 1994. The suppressor of hairless protein participates in notch receptor signaling. Cell 79:273-282.
    • (1994) Cell , vol.79 , pp. 273-282
    • Fortini, M.E.1    Artavanis-Tsakonas, S.2
  • 20
    • 0027378244 scopus 로고
    • An activated Notch receptor blocks cell-fate commitment in the developing Drosophila eye
    • Fortini, M. E., I. Rebay, L. A. Caron, and S. Artavanis-Tsakonas. 1993. An activated Notch receptor blocks cell-fate commitment in the developing Drosophila eye. Nature 365:555-557.
    • (1993) Nature , vol.365 , pp. 555-557
    • Fortini, M.E.1    Rebay, I.2    Caron, L.A.3    Artavanis-Tsakonas, S.4
  • 21
    • 0031975771 scopus 로고    scopus 로고
    • Characterization of the CBF2 binding site within the Epstein-Barr virus latency C promoter and its role in modulating EBNA2-mediated transactivation
    • Fuentes-Panana, E. M., and P. D. Ling. 1998. Characterization of the CBF2 binding site within the Epstein-Barr virus latency C promoter and its role in modulating EBNA2-mediated transactivation. J. Virol. 72:693-700.
    • (1998) J. Virol. , vol.72 , pp. 693-700
    • Fuentes-Panana, E.M.1    Ling, P.D.2
  • 22
    • 0030920376 scopus 로고    scopus 로고
    • The mouse mammary tumor associated gene INT3 is a unique member of the NOTCH gene family (NOTCH4)
    • Gallahan, D., and R. Callahan. 1997. The mouse mammary tumor associated gene INT3 is a unique member of the NOTCH gene family (NOTCH4). Oncogene 14:1883-1890.
    • (1997) Oncogene , vol.14 , pp. 1883-1890
    • Gallahan, D.1    Callahan, R.2
  • 23
    • 0029871104 scopus 로고    scopus 로고
    • Expression of a truncated Int3 gene in developing secretory mammary epithelium specifically retards lobular differentiation resulting in tumorigenesis
    • Gallahan, D., C. Jhappan, G. Robinson, L. Hennighausen, R. Sharp, E. Kordon, R. Callahan, G. Merlino, and G. H. Smith. 1996. Expression of a truncated Int3 gene in developing secretory mammary epithelium specifically retards lobular differentiation resulting in tumorigenesis. Cancer Res. 56: 1775-1785.
    • (1996) Cancer Res. , vol.56 , pp. 1775-1785
    • Gallahan, D.1    Jhappan, C.2    Robinson, G.3    Hennighausen, L.4    Sharp, R.5    Kordon, E.6    Callahan, R.7    Merlino, G.8    Smith, G.H.9
  • 24
    • 0023226698 scopus 로고
    • A new common integration region (int-3) for mouse mammary tumor virus on mouse chromosome 17
    • Gallahan, D., C. Kozak, and R. Callahan. 1987. A new common integration region (int-3) for mouse mammary tumor virus on mouse chromosome 17. J. Virol. 61:218-220.
    • (1987) J. Virol. , vol.61 , pp. 218-220
    • Gallahan, D.1    Kozak, C.2    Callahan, R.3
  • 25
    • 0032055258 scopus 로고    scopus 로고
    • A role for Ab1 in Notch signaling
    • Giniger, E. 1998. A role for Ab1 in Notch signaling. Neuron 20:667-681.
    • (1998) Neuron , vol.20 , pp. 667-681
    • Giniger, E.1
  • 26
    • 0029808295 scopus 로고    scopus 로고
    • Frequent provirus insertional mutagenesis of Notch1 in thymomas of MMTVD/myc transgenic mice suggests a collaboration of c-myc and Notch1 for oncogenesis
    • Girard, L., Z. Hanna, N. Beaulieu, C. D. Hoemann, C. Simard, C. A. Kozak, and P. Jolicoeur. 1996. Frequent provirus insertional mutagenesis of Notch1 in thymomas of MMTVD/myc transgenic mice suggests a collaboration of c-myc and Notch1 for oncogenesis. Genes Dev. 10:1930-1944.
    • (1996) Genes Dev. , vol.10 , pp. 1930-1944
    • Girard, L.1    Hanna, Z.2    Beaulieu, N.3    Hoemann, C.D.4    Simard, C.5    Kozak, C.A.6    Jolicoeur, P.7
  • 27
    • 0032525964 scopus 로고    scopus 로고
    • LIN-12/Notch signaling: Lessons from worms and flies
    • Greenwald, I. 1998. LIN-12/Notch signaling: lessons from worms and flies. Genes Dev. 12:1751-1762.
    • (1998) Genes Dev. , vol.12 , pp. 1751-1762
    • Greenwald, I.1
  • 28
    • 0344549859 scopus 로고    scopus 로고
    • Regulation of RelA subcellular localization by a putative nuclear export signal and p50
    • Harhaj, E. W., and S. C. Sun. 1999. Regulation of RelA subcellular localization by a putative nuclear export signal and p50. Mol. Cell. Biol. 19:7088-7095.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 7088-7095
    • Harhaj, E.W.1    Sun, S.C.2
  • 29
    • 0029062934 scopus 로고
    • Expression of a Delta homologue in prospective neurons in the chick
    • Henrique, D., J. Adam, A. Myat, A. Chitnis, J. Lewis, and D. Ish-Horowicz. 1995. Expression of a Delta homologue in prospective neurons in the chick. Nature 375:787-790.
    • (1995) Nature , vol.375 , pp. 787-790
    • Henrique, D.1    Adam, J.2    Myat, A.3    Chitnis, A.4    Lewis, J.5    Ish-Horowicz, D.6
  • 30
    • 0029678250 scopus 로고    scopus 로고
    • The shortest path from the surface to the nucleus: RBP-J kappa/Su(H) transcription factor
    • Honjo, T. 1996. The shortest path from the surface to the nucleus: RBP-J kappa/Su(H) transcription factor. Genes Cells 1:1-9.
    • (1996) Genes Cells , vol.1 , pp. 1-9
    • Honjo, T.1
  • 31
    • 0030063909 scopus 로고    scopus 로고
    • Truncated mammalian Notch1 activates CBF1/RBPJκ-repressed genes by a mechanism resembling that of Epstein-Barr virus EBNA2
    • Hsieh, J. J., T. Henkel, P. Salmon, E. Robey, M. G. Peterson, and S. D. Hayward. 1996. Truncated mammalian Notch1 activates CBF1/RBPJκ-repressed genes by a mechanism resembling that of Epstein-Barr virus EBNA2. Mol. Cell. Biol. 16:952-959.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 952-959
    • Hsieh, J.J.1    Henkel, T.2    Salmon, P.3    Robey, E.4    Peterson, M.G.5    Hayward, S.D.6
  • 32
    • 0031047971 scopus 로고    scopus 로고
    • Epstein-Barr virus immortalization: Notch2 interacts with CBF1 and blocks differentiation
    • Hsieh, J. J., D. E. Nofziger, G. Weinmaster, and S. D. Hayward. 1997. Epstein-Barr virus immortalization: Notch2 interacts with CBF1 and blocks differentiation. J. Virol. 71:1938-1945.
    • (1997) J. Virol. , vol.71 , pp. 1938-1945
    • Hsieh, J.J.1    Nofziger, D.E.2    Weinmaster, G.3    Hayward, S.D.4
  • 33
    • 0033524444 scopus 로고    scopus 로고
    • CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex
    • Hsieh, J. J., S. Zhou, L. Chen, D. B. Young, and S. D. Hayward. 1999. CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex. Proc. Natl. Acad. Sci. USA 96:23-28.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 23-28
    • Hsieh, J.J.1    Zhou, S.2    Chen, L.3    Young, D.B.4    Hayward, S.D.5
  • 34
    • 0030056206 scopus 로고    scopus 로고
    • Evidence for physical and functional association between EMB-5 and LIN-12 in Caenorhabditis elegans
    • Hubbard, E. J., Q. Dong, and I. Greenwald. 1996. Evidence for physical and functional association between EMB-5 and LIN-12 in Caenorhabditis elegans. Science 273:112-115.
    • (1996) Science , vol.273 , pp. 112-115
    • Hubbard, E.J.1    Dong, Q.2    Greenwald, I.3
  • 37
    • 0033556251 scopus 로고    scopus 로고
    • Protective effects of notch-1 on TCR-induced apoptosis
    • Jehn, B. M., W. Bielke, W. S. Pear, and B. A. Osborne. 1999. Protective effects of notch-1 on TCR-induced apoptosis. J. Immunol. 162:635-638.
    • (1999) J. Immunol. , vol.162 , pp. 635-638
    • Jehn, B.M.1    Bielke, W.2    Pear, W.S.3    Osborne, B.A.4
  • 38
    • 0030938788 scopus 로고    scopus 로고
    • The Notch ligand, X-Delta-2, mediates segmentation of the paraxial mesoderm in Xenopus embryos
    • Jen, W. C., D. Wettstein, D. Turner, A. Chitnis, and C. Kintner. 1997. The Notch ligand, X-Delta-2, mediates segmentation of the paraxial mesoderm in Xenopus embryos. Development 124:1169-1178.
    • (1997) Development , vol.124 , pp. 1169-1178
    • Jen, W.C.1    Wettstein, D.2    Turner, D.3    Chitnis, A.4    Kintner, C.5
  • 39
    • 0021716406 scopus 로고
    • A short amino acid sequence able to specify nuclear location
    • Kalderon, D., B. L. Roberts, W. D. Richardson, and A. E. Smith. 1984. A short amino acid sequence able to specify nuclear location. Cell 39:499-509.
    • (1984) Cell , vol.39 , pp. 499-509
    • Kalderon, D.1    Roberts, B.L.2    Richardson, W.D.3    Smith, A.E.4
  • 41
    • 0032417174 scopus 로고    scopus 로고
    • Ligand-induced cleavage and regulation of nuclear entry of Notch in Drosophila melanogaster embryos
    • Kidd, S., T. Lieber, and M. W. Young. 1998. Ligand-induced cleavage and regulation of nuclear entry of Notch in Drosophila melanogaster embryos. Genes Dev. 12:3728-3740.
    • (1998) Genes Dev. , vol.12 , pp. 3728-3740
    • Kidd, S.1    Lieber, T.2    Young, M.W.3
  • 42
    • 0027058492 scopus 로고
    • Molecular basis of loss-of-function mutations in the glp-1 gene of Caenorhabditis elegans
    • Kodoyianni, V., E. M. Maine, and J. Kimble. 1992. Molecular basis of loss-of-function mutations in the glp-1 gene of Caenorhabditis elegans. Mol. Biol. Cell 3:1199-1213.
    • (1992) Mol. Biol. Cell , vol.3 , pp. 1199-1213
    • Kodoyianni, V.1    Maine, E.M.2    Kimble, J.3
  • 43
    • 0027991383 scopus 로고
    • The intracellular domain of mouse Notch: A constitutively activated represser of myogenesis directed at the basic helix-loop-helix region of MyoD
    • Kopan, R., J. S. Nye, and H. Weintraub. 1994. The intracellular domain of mouse Notch: a constitutively activated represser of myogenesis directed at the basic helix-loop-helix region of MyoD. Development 120:2385-2396.
    • (1994) Development , vol.120 , pp. 2385-2396
    • Kopan, R.1    Nye, J.S.2    Weintraub, H.3
  • 44
    • 0030003538 scopus 로고    scopus 로고
    • Signal transduction by activated mNotch: Importance of proteolytic processing and its regulation by the extracellular domain
    • Kopan, R., E. H. Schroeter, H. Weintraub, and J. S. Nye. 1996. Signal transduction by activated mNotch: importance of proteolytic processing and its regulation by the extracellular domain. Proc. Natl. Acad. Sci. USA 93: 1683-1688.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 1683-1688
    • Kopan, R.1    Schroeter, E.H.2    Weintraub, H.3    Nye, J.S.4
  • 45
    • 0027318636 scopus 로고
    • Mouse notch: Expression in hair follicles correlates with cell fate determination
    • Kopan, R., and H. Weintraub. 1993. Mouse notch: expression in hair follicles correlates with cell fate determination. J. Cell Biol. 121:631-641.
    • (1993) J. Cell Biol. , vol.121 , pp. 631-641
    • Kopan, R.1    Weintraub, H.2
  • 47
    • 0033548489 scopus 로고    scopus 로고
    • Delta-induced Notch signaling mediated by RBP-J inhibits MyoD expression and myogenesis
    • Kuroda, K., S. Tani, K. Tamura, S. Minoguchi, H. Kurooka, and T. Honjo. 1999. Delta-induced Notch signaling mediated by RBP-J inhibits MyoD expression and myogenesis. J. Biol. Chem. 274:7238-7244.
    • (1999) J. Biol. Chem. , vol.274 , pp. 7238-7244
    • Kuroda, K.1    Tani, S.2    Tamura, K.3    Minoguchi, S.4    Kurooka, H.5    Honjo, T.6
  • 48
    • 0032403190 scopus 로고    scopus 로고
    • Roles of the ankyrin repeats and C-terminal region of the mouse notch1 intracellular region
    • Erratum, 27:following 1407, 1999
    • Kurooka, H., K. Kuroda, and T. Honjo. 1998. Roles of the ankyrin repeats and C-terminal region of the mouse notch1 intracellular region. Nucleic Acids Res. 26:5448-5455. (Erratum, 27:following 1407, 1999.)
    • (1998) Nucleic Acids Res. , vol.26 , pp. 5448-5455
    • Kurooka, H.1    Kuroda, K.2    Honjo, T.3
  • 49
    • 0028289647 scopus 로고
    • The novel Notch homologue mouse Notch 3 lacks specific epidermal growth factor-repeats and is expressed in proliferating neuroepithelium
    • Lardelli, M., J. Dahlstrand, and U. Lendahl. 1994. The novel Notch homologue mouse Notch 3 lacks specific epidermal growth factor-repeats and is expressed in proliferating neuroepithelium. Mech. Dev. 46:123-136.
    • (1994) Mech. Dev. , vol.46 , pp. 123-136
    • Lardelli, M.1    Dahlstrand, J.2    Lendahl, U.3
  • 50
    • 0028605515 scopus 로고
    • The human NOTCH1, 2, and 3 genes are located at chromosome positions 9q34, 1p13-p11, and 19p13.2-p13.1 in regions of neoplasia-associated translocation
    • Larsson, C., M. Lardelli, I. White, and U. Lendahl. 1994. The human NOTCH1, 2, and 3 genes are located at chromosome positions 9q34, 1p13-p11, and 19p13.2-p13.1 in regions of neoplasia-associated translocation. Genomics 24:253-258.
    • (1994) Genomics , vol.24 , pp. 253-258
    • Larsson, C.1    Lardelli, M.2    White, I.3    Lendahl, U.4
  • 51
    • 0032543565 scopus 로고    scopus 로고
    • Indirect evidence for Delta-dependent intracellular processing of notch in Drosophila embryos
    • Lecourtois, M., and F. Schweisguth. 1998. Indirect evidence for Delta-dependent intracellular processing of notch in Drosophila embryos. Curr. Biol. 8:771-774.
    • (1998) Curr. Biol. , vol.8 , pp. 771-774
    • Lecourtois, M.1    Schweisguth, F.2
  • 52
    • 0027386233 scopus 로고
    • Antineurogenic phenotypes induced by truncated Notch proteins indicate a role in signal transduction and may point to a novel function for Notch in nuclei
    • Lieber, T., S. Kidd, E. Alcamo, V. Corbin, and M. W. Young. 1993. Antineurogenic phenotypes induced by truncated Notch proteins indicate a role in signal transduction and may point to a novel function for Notch in nuclei. Genes Dev. 7:1949-1965.
    • (1993) Genes Dev. , vol.7 , pp. 1949-1965
    • Lieber, T.1    Kidd, S.2    Alcamo, E.3    Corbin, V.4    Young, M.W.5
  • 53
    • 0030199830 scopus 로고    scopus 로고
    • Expression patterns of Jagged, Delta1, Notch1, Notch2, and Notch3 genes identify ligand-receptor pairs that may function in neural development
    • Lindsell, C. E., J. Boulter, G. diSibio, A. Gossler, and G. Weinmaster. 1996. Expression patterns of Jagged, Delta1, Notch1, Notch2, and Notch3 genes identify ligand-receptor pairs that may function in neural development. Mol. Cell Neurosci. 8:14-27.
    • (1996) Mol. Cell Neurosci. , vol.8 , pp. 14-27
    • Lindsell, C.E.1    Boulter, J.2    DiSibio, G.3    Gossler, A.4    Weinmaster, G.5
  • 54
    • 0030046140 scopus 로고    scopus 로고
    • Epithelial expression and chromosomal location of human TLE genes: Implications for notch signaling and neoplasia
    • Liu, Y., G. Dehni, K. J. Purcell, J. Sokolow, M. L. Carcangiu, S. Artavanis-Tsakonas, and S. Stifani. 1996. Epithelial expression and chromosomal location of human TLE genes: implications for notch signaling and neoplasia. Genomics 31:58-64.
    • (1996) Genomics , vol.31 , pp. 58-64
    • Liu, Y.1    Dehni, G.2    Purcell, K.J.3    Sokolow, J.4    Carcangiu, M.L.5    Artavanis-Tsakonas, S.6    Stifani, S.7
  • 56
    • 0030693878 scopus 로고    scopus 로고
    • Suppressor of Hairless-independent events in Notch signaling imply novel pathway elements
    • Matsuno, K., M. J. Go, X. Sun, D. S. Eastman, and S. Artavanis-Tsakonas. 1997. Suppressor of Hairless-independent events in Notch signaling imply novel pathway elements. Development 124:4265-4273.
    • (1997) Development , vol.124 , pp. 4265-4273
    • Matsuno, K.1    Go, M.J.2    Sun, X.3    Eastman, D.S.4    Artavanis-Tsakonas, S.5
  • 57
    • 0032695278 scopus 로고    scopus 로고
    • Arbiter of differentiation and death: Notch signaling meets apoptosis
    • Miele, L., and B. Osborne. 1999. Arbiter of differentiation and death: notch signaling meets apoptosis. J. Cell Physiol. 181:393-409.
    • (1999) J. Cell Physiol. , vol.181 , pp. 393-409
    • Miele, L.1    Osborne, B.2
  • 58
    • 0033561454 scopus 로고    scopus 로고
    • Notch as a mediator of cell fate determination in hematopoiesis: Evidence and speculation
    • Milner, L. A., and A. Bigas. 1999. Notch as a mediator of cell fate determination in hematopoiesis: evidence and speculation. Blood 93:2431-2448.
    • (1999) Blood , vol.93 , pp. 2431-2448
    • Milner, L.A.1    Bigas, A.2
  • 60
    • 0029925224 scopus 로고    scopus 로고
    • A chick homologue of Serrate and its relationship with Notch and Delta homologues during central neurogenesis
    • Myat, A., D. Henrique, D. Ish-Horowicz, and J. Lewis. 1996. A chick homologue of Serrate and its relationship with Notch and Delta homologues during central neurogenesis. Dev. Biol. 174:233-247.
    • (1996) Dev. Biol. , vol.174 , pp. 233-247
    • Myat, A.1    Henrique, D.2    Ish-Horowicz, D.3    Lewis, J.4
  • 61
    • 0032915458 scopus 로고    scopus 로고
    • Notch signaling imposes two distinct blocks in the differentiation of C2C12 myoblasts
    • Nofziger, D., A. Miyamoto, K. M. Lyons, and G. Weinmaster. 1999. Notch signaling imposes two distinct blocks in the differentiation of C2C12 myoblasts. Development 126:1689-1702.
    • (1999) Development , vol.126 , pp. 1689-1702
    • Nofziger, D.1    Miyamoto, A.2    Lyons, K.M.3    Weinmaster, G.4
  • 62
    • 0029363136 scopus 로고
    • Developmental signaling. Vertebrate ligands for Notch
    • Nye, J. S., and R. Kopan. 1995. Developmental signaling. Vertebrate ligands for Notch. Curr. Biol. 5:966-969.
    • (1995) Curr. Biol. , vol.5 , pp. 966-969
    • Nye, J.S.1    Kopan, R.2
  • 63
    • 0027966977 scopus 로고
    • An activated Notch suppresses neurogenesis and myogenesis but not gliogenesis in mammalian cells
    • Nye, J. S., R. Kopan, and R. Axel. 1994. An activated Notch suppresses neurogenesis and myogenesis but not gliogenesis in mammalian cells. Development 120:2421-2430.
    • (1994) Development , vol.120 , pp. 2421-2430
    • Nye, J.S.1    Kopan, R.2    Axel, R.3
  • 64
    • 0031213641 scopus 로고    scopus 로고
    • Identification and cloning of the human homolog (JAG1) of the rat Jagged1 gene from the Alagille syndrome critical region at 20p12
    • Oda, T., A. G. Elkahloun, P. S. Meltzer, and S. C. Chandrasekharappa. 1997. Identification and cloning of the human homolog (JAG1) of the rat Jagged1 gene from the Alagille syndrome critical region at 20p12. Genomics 43:376-379.
    • (1997) Genomics , vol.43 , pp. 376-379
    • Oda, T.1    Elkahloun, A.G.2    Meltzer, P.S.3    Chandrasekharappa, S.C.4
  • 66
    • 0031594575 scopus 로고    scopus 로고
    • NF-κB2 is a putative target gene of activated Notch-1 via RBP-Jκ
    • Oswald, F., S. Liptay, G. Adler, and R. M. Schmid. 1998. NF-κB2 is a putative target gene of activated Notch-1 via RBP-Jκ Mol. Cell. Biol. 18: 2077-2088.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 2077-2088
    • Oswald, F.1    Liptay, S.2    Adler, G.3    Schmid, R.M.4
  • 67
    • 0029942842 scopus 로고    scopus 로고
    • Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles
    • Pear, W. S., J. C. Aster, M. L. Scott, R. P. Hasserjian, B. Soffer, J. Sklar, and D. Baltimore. 1996. Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles. J. Exp. Med. 183:2283-2291.
    • (1996) J. Exp. Med. , vol.183 , pp. 2283-2291
    • Pear, W.S.1    Aster, J.C.2    Scott, M.L.3    Hasserjian, R.P.4    Soffer, B.5    Sklar, J.6    Baltimore, D.7
  • 68
    • 0027236954 scopus 로고
    • Production of high-liter helper-free retroviruses by transient transfection
    • Pear, W. S., G. P. Nolan, M. L. Scott, and D. Baltimore. 1993. Production of high-liter helper-free retroviruses by transient transfection. Proc. Natl. Acad. Sci. USA 90:8392-8396.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 8392-8396
    • Pear, W.S.1    Nolan, G.P.2    Scott, M.L.3    Baltimore, D.4
  • 70
    • 0026554890 scopus 로고
    • Mouse mammary tumor gene int-3: A member of the notch gene family transforms mammary epithelial cells
    • Robbins, J., B. J. Blondel, D. Gallahan, and R. Callahan. 1992. Mouse mammary tumor gene int-3: a member of the notch gene family transforms mammary epithelial cells. J. Virol. 66:2594-2599.
    • (1992) J. Virol. , vol.66 , pp. 2594-2599
    • Robbins, J.1    Blondel, B.J.2    Gallahan, D.3    Callahan, R.4
  • 71
    • 0030853591 scopus 로고    scopus 로고
    • Notch in vertebrates
    • Robey, E. 1997. Notch in vertebrates. Curr. Opin. Genet. Dev. 7:551-557.
    • (1997) Curr. Opin. Genet. Dev. , vol.7 , pp. 551-557
    • Robey, E.1
  • 72
    • 0030477188 scopus 로고    scopus 로고
    • Roles of the RAM and ANK domains in signaling by the C. elegans GLP-1 receptor
    • Roehl, H., M. Bosenberg, R. Blelloch, and J. Kimble. 1996. Roles of the RAM and ANK domains in signaling by the C. elegans GLP-1 receptor. EMBO J. 15:7002-7012.
    • (1996) EMBO J. , vol.15 , pp. 7002-7012
    • Roehl, H.1    Bosenberg, M.2    Blelloch, R.3    Kimble, J.4
  • 73
    • 0027291722 scopus 로고
    • Control of cell fate in C. elegans by a GLP-1 peptide consisting primarily of ankyrin repeats
    • Roehl, H., and J. Kimble. 1993. Control of cell fate in C. elegans by a GLP-1 peptide consisting primarily of ankyrin repeats. Nature 364:632-635.
    • (1993) Nature , vol.364 , pp. 632-635
    • Roehl, H.1    Kimble, J.2
  • 74
    • 0029819876 scopus 로고    scopus 로고
    • Transduction of Notch2 in feline leukemia virus-induced thymic lymphoma
    • Rohn, J. L., A. S. Lauring, M. L. Linenberger, and J. Overbaugh. 1996. Transduction of Notch2 in feline leukemia virus-induced thymic lymphoma. J. Virol. 70:8071-8080.
    • (1996) J. Virol. , vol.70 , pp. 8071-8080
    • Rohn, J.L.1    Lauring, A.S.2    Linenberger, M.L.3    Overbaugh, J.4
  • 75
    • 0032574993 scopus 로고    scopus 로고
    • Notch-1 signalling requires tigand-induced proteolytic release of intracellular domain
    • Schroeter, E. H., J. A. Kisslinger, and R. Kopan. 1998. Notch-1 signalling requires tigand-induced proteolytic release of intracellular domain. Nature 393:382-386.
    • (1998) Nature , vol.393 , pp. 382-386
    • Schroeter, E.H.1    Kisslinger, J.A.2    Kopan, R.3
  • 76
    • 0033595679 scopus 로고    scopus 로고
    • Contact-dependent inhibition of cortical neurite growth mediated by notch signaling
    • Sestan, N., S. Artavanis-Tsakonas, and P. Rakic. 1999. Contact-dependent inhibition of cortical neurite growth mediated by notch signaling. Science 286:741-746.
    • (1999) Science , vol.286 , pp. 741-746
    • Sestan, N.1    Artavanis-Tsakonas, S.2    Rakic, P.3
  • 77
    • 0030602065 scopus 로고    scopus 로고
    • Jagged2: A serrate-like gene expressed during rate embryogenesis
    • Shawber, C., J. Boulter, C. E. Lindsell, and G. Weinmaster. 1996. Jagged2: a serrate-like gene expressed during rate embryogenesis. Dev. Biol. 180:370-376.
    • (1996) Dev. Biol. , vol.180 , pp. 370-376
    • Shawber, C.1    Boulter, J.2    Lindsell, C.E.3    Weinmaster, G.4
  • 79
    • 0027500140 scopus 로고
    • 1/S-specinc transcription in Saccharomyces cerevisiae
    • 1/S-specinc transcription in Saccharomyces cerevisiae. Mol. Cell. Biol. 13:1069-1077.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 1069-1077
    • Sidorova, J.1    Breeden, L.2
  • 80
    • 0029002597 scopus 로고
    • Constitutive expression of a truncated INT3 gene in mouse mammary epithelium impairs differentiation and functional development
    • Smith, G. H., D. Gallahan, F. Diella, C. Jhappan, G. Merlino, and R. Callahan. 1995. Constitutive expression of a truncated INT3 gene in mouse mammary epithelium impairs differentiation and functional development. Cell Growth Differ. 6:563-577.
    • (1995) Cell Growth Differ. , vol.6 , pp. 563-577
    • Smith, G.H.1    Gallahan, D.2    Diella, F.3    Jhappan, C.4    Merlino, G.5    Callahan, R.6
  • 81
    • 0032524325 scopus 로고    scopus 로고
    • Nuclear access and action of notch in vivo
    • Struhl, G., and A. Adachi. 1998. Nuclear access and action of notch in vivo. Cell 93:649-660.
    • (1998) Cell , vol.93 , pp. 649-660
    • Struhl, G.1    Adachi, A.2
  • 82
    • 0027219557 scopus 로고
    • Intrinsic activity of the Lin-12 and Notch intracellular domains in vivo
    • Struhl, G., K. Fitzgerald, and I. Greenwald. 1993. Intrinsic activity of the Lin-12 and Notch intracellular domains in vivo. Cell 74:331-345.
    • (1993) Cell , vol.74 , pp. 331-345
    • Struhl, G.1    Fitzgerald, K.2    Greenwald, I.3
  • 83
    • 0033535508 scopus 로고    scopus 로고
    • Presenilin is required for activity and nuclear access of Notch in Drosophila
    • Struhl, G., and I. Greenwald. 1999. Presenilin is required for activity and nuclear access of Notch in Drosophila. Nature 398:522-525.
    • (1999) Nature , vol.398 , pp. 522-525
    • Struhl, G.1    Greenwald, I.2
  • 84
    • 0029583607 scopus 로고
    • Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-J kappa/Su(H)
    • Tamura, K., Y. Taniguchi, S. Minoguchi, T. Sakai, T. Tun, T. Furukawa, and T. Honjo. 1995. Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-J kappa/Su(H). Curr. Biol. 5:1416-1423.
    • (1995) Curr. Biol. , vol.5 , pp. 1416-1423
    • Tamura, K.1    Taniguchi, Y.2    Minoguchi, S.3    Sakai, T.4    Tun, T.5    Furukawa, T.6    Honjo, T.7
  • 86
    • 0030054646 scopus 로고    scopus 로고
    • Notch4/int-3, a mammary proto-oncogene, is an endothelial cell-specific mammalian Notch gene
    • Uyttendaele, M., G. Marazzi, G. Wu, Q. Yan, D. Sassoon, and J. Kitajewski. 1996. Notch4/int-3, a mammary proto-oncogene, is an endothelial cell-specific mammalian Notch gene. Development 122:2251-2259.
    • (1996) Development , vol.122 , pp. 2251-2259
    • Uyttendaele, M.1    Marazzi, G.2    Wu, G.3    Yan, Q.4    Sassoon, D.5    Kitajewski, J.6
  • 87
    • 0031431128 scopus 로고    scopus 로고
    • JAGGED2: A putative Notch ligand expressed in the apical ectodermal ridge and in sites of epithelial-mesenchymal interactions
    • Valsecchi, C., C. Ghezzi, A. Ballabio, and E. I. Rugarli. 1997. JAGGED2: a putative Notch ligand expressed in the apical ectodermal ridge and in sites of epithelial-mesenchymal interactions. Mech. Dev. 69:203-207.
    • (1997) Mech. Dev. , vol.69 , pp. 203-207
    • Valsecchi, C.1    Ghezzi, C.2    Ballabio, A.3    Rugarli, E.I.4
  • 88
    • 0033136704 scopus 로고    scopus 로고
    • NUMB localizes in the basal cortex of mitotic avian neuroepithelial cells and modulates neuronal differentiation by binding to NOTCH-1
    • Wakamatsu, Y., T. M. Maynard, S. U. Jones, and J. A. Weston. 1999. NUMB localizes in the basal cortex of mitotic avian neuroepithelial cells and modulates neuronal differentiation by binding to NOTCH-1. Neuron 23:71-81.
    • (1999) Neuron , vol.23 , pp. 71-81
    • Wakamatsu, Y.1    Maynard, T.M.2    Jones, S.U.3    Weston, J.A.4
  • 89
    • 0030700813 scopus 로고    scopus 로고
    • Only a subset of the binary cell fate decisions mediated by Numb/Notch signaling in Drosophila sensory organ lineage requires Suppressor of Hairless
    • Wang, S., S. Younger-Shepherd, L. Y. Jan, and Y. N. Jan. 1997. Only a subset of the binary cell fate decisions mediated by Numb/Notch signaling in Drosophila sensory organ lineage requires Suppressor of Hairless. Development 124:4435-4446.
    • (1997) Development , vol.124 , pp. 4435-4446
    • Wang, S.1    Younger-Shepherd, S.2    Jan, L.Y.3    Jan, Y.N.4
  • 90
    • 0025866773 scopus 로고
    • A homolog of Drosophila Notch expressed during mammalian development
    • Weinmaster, G., V. J. Roberts, and G. Lemke. 1991. A homolog of Drosophila Notch expressed during mammalian development. Development 113: 199-205.
    • (1991) Development , vol.113 , pp. 199-205
    • Weinmaster, G.1    Roberts, V.J.2    Lemke, G.3
  • 91
    • 0027052807 scopus 로고
    • Notch2: A second mammalian Notch gene
    • Weinmaster, G., V. J. Roberts, and G. Lemke. 1992. Notch2: a second mammalian Notch gene. Development 116:931-941.
    • (1992) Development , vol.116 , pp. 931-941
    • Weinmaster, G.1    Roberts, V.J.2    Lemke, G.3
  • 92
    • 0029130168 scopus 로고
    • Identification of a signal for rapid export of proteins from the nucleus
    • Wen, W., J. L. Meinkoth, R. Y. Tsien, and S. S. Taylor. 1995. Identification of a signal for rapid export of proteins from the nucleus. Cell 82:463-473.
    • (1995) Cell , vol.82 , pp. 463-473
    • Wen, W.1    Meinkoth, J.L.2    Tsien, R.Y.3    Taylor, S.S.4
  • 94
    • 0032560766 scopus 로고    scopus 로고
    • Defects in somite formation in lunatic fringe-deficient mice
    • Zhang, N., and T. Gridley. 1998. Defects in somite formation in lunatic fringe-deficient mice. Nature 394:374-377.
    • (1998) Nature , vol.394 , pp. 374-377
    • Zhang, N.1    Gridley, T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.