Notch signalling via RBP-J promotes myeloid differentiation

EMBO Journal

Volumn 19, Issue 11, 2000, Pages 2558-2568

  Schroeder, Timm ^a   Just, Ursula ^a  

^a INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

Differentiation; Hematopoiesis; mNotch1; RBP J; Signalling

Indexed keywords

4 HYDROXYTAMOXIFEN; BINDING PROTEIN; NOTCH RECEPTOR;

ARTICLE; BONE MARROW CELL; CELL DIFFERENTIATION; FIBROBLAST; GRANULOCYTE; MYELOPOIESIS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; STEM CELL;

EID: 0034212342     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/19.11.2558     Document Type: Article

References (61)

1. Artavanis-Tsakonas, S., Matsuno, K. and Fortini, M. (1995) Notch signalling. Science, 268, 225-232.
2. Bettenhausen, B., Hrabe de Angelis, M., Simon, D., Guenet, J. and Gossler, A. (1995) Transient and restricted expression during mouse embryogenesis of D111, a murine gene closely related to Drosophila Delta. Development, 121, 2407-2418.
3. Bigas, A., Martin, D. and Milner, L. (1998) Notch1 and Notch2 inhibit myeloid differentiation in response to different cytokines. Mol. Cell. Biol., 18, 2324-2333.
4. Carlesso, N., Aster, J., Sklar, J. and Scadden, D. (1999) Notch1-induced delay of human haemopoietic progenitor cell differentiation is associated with altered cell cycle kinetics. Blood, 93, 838-848.
5. Deftos, M., He, Y.-W., Ojala, E. and Bevan, M. (1998) Correlating Notch signaling with thymocyte maturation. Immunity, 9, 777-786.
6. Del Amo, F., Smith, D., Swiatek, P., Gendron-Maguire, M., Greenspan, R., McMahon, A. and Gridley, T. (1992) Expression pattern of Motch, a mouse homolog of Drosophila Notch, suggests an important role in early postimplantation mouse development. Development. 115, 737-744.
7. Del Amo, F., Gendron, M., Swiatek, P., Jenkins, N., Copeland, N. and Gridley, T. (1993) Cloning, analysis, and chromosomal localization of Notch-1, a mouse homolog of Drosophila Notch. Genomics, 15, 259-264.
8. de la Pompa, J. et al. (1997) Conservation of the Notch signalling pathway in mammalian neurogenesis. Development, 124, 1139-1148.
9. Dunwoodie, S., Henrique, D., Harrison, S. and Beddinglon, S. (1997) Mouse DII3: a novel divergent Delta gene which may complement the function of other Delta homologues during early pattern formation in the mouse embryo. Development, 124, 3065-3076.
10. Ellisen, L., Bird, J., West, D., Soreng, A., Reynolds, T., Smith, S. and Sklar, J. (1991) TAN-I, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms. Cell, 66, 649-661.
11. Feil, R., Wagner, J., Metzger, D. and Chambon, P. (1997) Regulation of Cre recombinase activity by mutated estrogen receptor ligand-binding domains. Biochem. Biophys. Res. Commun., 237, 752-757.
12. Gossen, M. and Bujard, H. (1992) Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc. Natl Acad. Sci. USA, 89, 547-5551.
13. Grez, M., Akgün, E., Hilberg, F. and Ostertag, W. (1990) Embryonic stem cell virus, a recombinant murine retrovirus with expression in embryonic stem cells. Proc. Natl Acad. Sci. USA, 87, 9202-9206.
14. Han, W., Ye, Q. and Moore, M. (2000) A soluble form of human Delta-like-1 inhibits differentiation of hematopoietic progenitor cells. Blood, 95, 1616-1625.
15. Höfelmayr, H., Strobl, L., Stein, C. Laux, G., Marschall, G., Bornkamm, G. and Zimber-Strobl, U. (1999) Activated mouse Notch1 transactivates Epstein-Barr virus nuclear antigen 2-regulated viral promoters. J. Virol., 73, 2770-2780.
16. Hsieh, J., Henkel, T., Salmon, P., Robey, E., Peterson, M. and Hayward, S. (1996) Truncated mammalian Notch1 activates CBFI/RBPJk-repressed genes by a mechanism resembling that of Epstein-Barr virus EBNA2. Mol. Cell. Biol., 16, 952-959.
17. Hukriede, N., Gu, Y. and Fleming, R. (1997) A dominant-negative form of Serrate acts as a general antagonist of Notch activation. Development, 124, 3427-3437.
18. Jarriault, S., Brou, C., Logeat, F., Schroeter, E., Kopan, R. and Israel, A. (1995) Signalling downstream of activated mammalian Notch. Nature, 377, 355-358.
19. Jones, P., May, G., Healy, L., Brown, J., Hoyne, G., Delassus, S. and Enver, T. (1998) Stromal expression of Jagged 1 promotes colony formation by fetal haemopoietic progenitor cells. Blood, 92, 1505-1511.
20. Karasuyama, H. and Melchers, F. (1988) Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 or 5 using cDNA expression vectors. Eur. J. Immunol., 18, 97-104.
21. Kato, H., Sakai, T., Tamura, K., Minoguchi, S., Shirayoshi, Y., Hamada, Y., Tsujimoto, Y. and Honjo, T. (1996) Functional conservation of mouse Notch receptor family members. FEBS Lett., 395, 221-224.
22. Kato, H., Taniguchi, Y., Kurooka, H., Minoguchi, S., Sakai, T., Nomura-Okazaki, S., Tamura, K. and Honjo, T. (1997) Involvement of RBP-J in biological functions of mouse Notch1 and its derivatives. Development, 124, 4133-4141.
23. Kopan, R. and Weintraub, H. (1993) Mouse notch: expression in hair follicles correlates with cell fate determination. J. Cell Biol., 121, 631-641.
24. Kopan, R., Nye, J. and Weintraub, H. (1994) The intracellular domain of mouse Notch: a constitutively activated repressor of myogenesis directed at the basic helix-loop-helix region of MyoD. Development, 120, 2385-2396.
25. Kopan, R., Schroeter, E., Weintraub, H. and Nye, J. (1996) Signal transduction by activated mNotch: importance of proteolytic processing and its regulation by the extracellular domain. Proc. Natl Acad. Sci. USA, 93, 1683-1688.
26. Kurooka, H., Kuroda, K. and Honjo, T. (1998) Roles of the ankyrin repeats and C-terminal region of the mouse Notch1 intracellular region. Nucleic Acids Res., 26, 5448-5455.
27. Laker, C., Meyer, J., Schopen, A., Friel, J., Heberlein, C., Ostertag, W. and Stocking, C. (1998) Host cis-mediated extinction of a retrovirus permissive for expression in embryonal stem cells during differentiation. J. Virol., 72, 339-348.
28. Lardelli, M. and Lendahl, U. (1993) Motch A and motch B - two mouse Notch homologues coexpressed in a wide variety of tissues. Exp. Cell Res., 204, 364-372.
29. Lardelli, M., Dahlstrand, J. and Lendahl, U. (1994) The novel Notch homologue mouse Notch 3 lacks specific epidermal growth factor repeats and is expressed in proliferating neuroepithelium. Mech. Dev., 46, 123-136.
30. Li, L. et al. (1998) The human homolog of rat Jagged1 expressed by marrow stroma inhibits differentiation of 32D cells through interaction with Notch1. Immunity, 8, 43-55.
31. Lindsell, C., Shawber, C., Boulter, J. and Weinmaster, G. (1995) Jagged: a mammalian ligand that activates Notch1. Cell, 80, 909-917.
32. Migliaccio, G., Migliaccio, A., Kreider, B., Rovera, G. and Adamson, J. (1989) Selection of lineage-restricted cell lines immortalized at different stages of haemopoietic differentiation from the murine cell line 32D. J. Cell Biol., 109, 833-841.
33. Milner, L. and Bigas, A. (1999) Notch as a mediator of cell fate determination in haemopoiesis: evidence and speculation. Blood, 93, 2431-2448.
34. Milner, L., Kopan, R., Mart́in, D. and Bernstein, I. (1994) A human homologue of the Drosophila developmental gene, Notch, is expressed in CD34+ haemopoietic precursors. Blood, 83, 2057-2062.
35. Milner, L., Bigas, A., Kopan, R., Brashem-Stein, C., Bernstein, I., and Martin, D. (1996) Inhibition of granulocytic differentiation by mNotch1. Proc. Natl Acad. Sci. USA, 93, 13014-13019.
36. Nofziger, D., Miyamoto, A., Lyons, K. and Weinmaster, G. (1999) Notch signaling imposes two distinct blocks in the differentiation of C2C12 myoblasts. Development, 126, 1689-1702.
37. Nye, J., Kopan, R. and Axel, R. (1994) An activated Notch suppresses neurogenesis and myogenesis but not gliogenesis in mammalian cells. Development, 120, 2421-2430.
38. Oka, C. et al. (1995) Disruption of the mouse RBP-J κ gene results in early embryonic death. Development, 121, 3291-3301.
39. Pui, J. et al. (1999) Notch1 expression in early lymphopoiesis influences B versus T lineage determination. Immunity, 11, 299-308.
40. Radtke, F., Wilson, A., Stark, G., Bauer, M., van Meerwijk, J., MacDonald, H. and Aguet, M. (1999) Deficient T cell fate specification in mice with an induced inactivation of Notch1. Immunity, 10, 547-558.
41. Reaume, A., Conlon, R., Zirngibl, R., Yamaguchi, T. and Rossant, J. (1992) Expression analysis of a Notch homologue in the mouse embryo. Dev. Biol., 154, 377-387.
42. Rebay, I., Fleming, R., Fehon, R., Cherbas, L., Cherbas, P. and Artavanis-Tsakonas, S. (1991) Specific EGF repeats of Notch mediate interactions with Delta and Serrate: implications for Notch as a multifunctional receptor. Cell, 67, 687-699.
43. Robey, E., Chang, D., Itano, A., Cado, D., Alexander, H., Lans, D., Weinmaster, G. and Salmon, B. (1996) An activated form of Notch influences the choice between CD4 and CD8 T cell lineages. Cell, 87, 483-492.
44. Schroeter, E., Kisslinger, J. and Kopan, R. (1998) Notch-1 signaling requires ligand-induced proteolytic release of intracellular domain. Nature, 393, 382-386.
45. Shawber, C., Boulter, J., Lindsell, C. and Weinmaster, G. (1996a) Jagged2: a serrate-like gene expressed during rat embryogenesis. Dev. Biol., 180, 370-376.
46. Shawber, C., Nofziger, D., Hsieh, J., Lindsell, C., Bogler, O., Hayward, D. and Weinmaster, G. (1996b) Notch signaling inhibits muscle cell differentiation through a CBF1-independent pathway. Development, 122, 3765-3773.
47. Shelly, L., Fuchs, C. and Miele, L. (1999) Notch-1 inhibits apoptosis in murine erythroleukemia cells and is necessary for differentiation induced by hybrid polar compounds. J. Cell. Biochem., 73, 164-175.
48. Simpson, P. (1995) The Notch connection. Nature, 375, 736-737.
49. Strobl, L., Höfelmayr, H., Stein, C., Marschall, G., Brielmeier, M., Laux, G., Bornkamm, G. and Zimber-Strobl, U. (1997) Both Epstein-Barr viral nuclear antigen 2 (EBNA2) and activated Notch1 transactivate genes by interacting with the cellular protein RBP-J κ. Immunobiology, 198, 299-306.
50. Sun, X. and Artavanis-Tsakonas, S. (1997) Secreted forms of DELTA and SERRATE define antagonists of Notch signaling in Drosophila. Development, 124, 3439-3448.
51. Tamura, K., Taniguchi, Y., Minoguchi, S., Sakai, T., Tun, T., Furukawa, T. and Honjo, T. (1995) Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-J κ/Su (H). Curr. Biol., 5, 1416-1423.
52. Tax, F., Yeargers, J. and Thomas, J. (1994) Sequence of C. elegans Lag-2 reveals a cell signaling domain shared with Delta and Serrate of Drosophila. Nature, 368, 150-154.
53. Uyttendaele, H., Marazzi, G., Wu, G., Yan, Q., Sassoon, D. and Kitajewski, J. (1996) Notch/int-3, a mammary proto-oncogene, is an endothelial cell-specific mammalian Notch gene. Development, 122, 2251-2259.
54. Valtieri, M., Tweardy, D., Caracciolo, D., Johnson, K., Mavilio, F., Altmann, S., Santoli, D. and Rovera, G. (1987) Cytokine-dependent granulocytic differentiation: regulation of proliferative and differentiative responses in a murine progenitor cell line. J. Immunol., 138, 3829-3835.
55. Varnum-Finney, B. et al. (1998) The Notch ligand, Jagged-1, influences the development of primitive haemopoietic precursor cells. Blood, 91, 4084-4091.
56. Walker, L., Lynch, M., Silverman, S., Fraser, J., Boulter, J., Weinmaster, G. and Gasson, J. (1999) The Notch/Jagged pathway inhibits proliferation of human haemopoietic progenitors in vitro. Stem Cells, 17, 162-171.
57. Waltzer, L., Bourillot, P., Sergeant, A. and Manet, E. (1995) RBP-J κ repression activity is mediated by a co-repressor and antagonized by the Epstein-Barr virus transcription factor EBNA2. Nucleic Acids Res., 23, 4939-4945.
58. Washburn, T., Schweighoffer, E., Gridley, T., Chang, D., Fowlkes, B., Cado, D. and Robey, E. (1997) Notch activity influences the αβ versus γδ T cell lineage decision. Cell, 88, 833-843.
59. Weinmaster, G. (1997) The ins and outs of notch signaling. Mol. Cell. Neurosci., 9, 91-102.
60. Weinmaster, G., Roberts, V. and Lemke, G. (1991) A homolog of Drosophila Notch expressed during mammalian development. Development, 113, 199-205.
61. Weinmaster, G., Roberts, V. and Lemke, G. (1992) Notch2: a second mammalian Notch gene. Development. 116, 931-941.