Alkyne metathesis: Development of a novel molybdenum-based catalyst system and its application to the total synthesis of epothilone A and C

Chemistry - A European Journal

Volumn 7, Issue 24, 2001, Pages 5299-5317

  Fürstner, Alois ^a   Mathes, Christian ^a   Lehmann, Christian W ^a  

^a MAX PLANCK INSTITUT FÜR KOHLENFORSCHUNG   (Germany)

Author keywords

Alkynes; Macrocycles; Metathesis; Molybdenum; Natural products

Indexed keywords

ACTIVATION ANALYSIS; CATALYSIS; HALOGEN COMPOUNDS; HYDROGENATION; MOLYBDENUM COMPOUNDS; SYNTHESIS (CHEMICAL); X RAY CRYSTALLOGRAPHY;

HALOGEN DONORS; RING CLOSING ALKYNE METATHESIS (RCAM);

CATALYSTS;

3,7 BIS(TERT BUTYLDIMETHYLSILANYLOXY) 4,4,6,8 TETRAMETHYL 5 OXOTETRADEC 12 YNOIC ACID 1 [1 METHYL 2 (2 METHYLTHIAZOL 4 YL)VINYL]PENT 3 YNYL ESTER; 4,8 BIS(TERT BUTYLDIMETHYLSILANYLOXY) 5,5,7,9 TETRAMETHYL 16 [1 METHYL 2 (2 METHYL 1,3 THIAZOL 4 YL) 1 VINYL] 1 OXACYCLOHEXADEC 13 ENE 2,6 DIONE; 4,8 BIS(TERT BUTYLDIMETHYLSILANYLOXY) 5,5,7,9 TETRAMETHYL 16 [1 METHYL 2 (2 METHYL 1,3 THIAZOL 4 YL) 1 VINYL] 1 OXACYCLOHEXADEC 13 YNE 2,6 DIONE; ALKENE DERIVATIVE; ALKYNE DERIVATIVE; ANTINEOPLASTIC AGENT; DICHLORO (3,5 DIMETHYLPHENYLIMIDO) BIS[N (TERT BUTYL)(3,5 DIMETHYLPHENYL)AMIDO]MOLYBDENUM; DICHLOROMETHANE; EPOTHILONE A; EPOTHILONE C; FUNCTIONAL GROUP; HALIDE; MACROLIDE; MOLYBDENUM; MOLYBDENUM COMPLEX; MONOCHLORO TRIS[N (TERT BUTYL)(3,5 DIMETHYLPHENYL)AMIDO]MOLYBDENUM; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CATALYST; CYCLIZATION; DRUG SYNTHESIS; EXTRACTION; HYDROGENATION; INTERMETHOD COMPARISON; STEREOCHEMISTRY; STEREOSPECIFICITY; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY;

EID: 0035905420     PISSN: 09476539     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-3765(20011217)7:24<5299::AID-CHEM5299>3.0.CO;2-X     Document Type: Article

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