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Volumn 2, Issue 16, 2000, Pages 2463-2465

Concise synthesis of (S,S)-(+)-dehydrohomoancepsenolide

Author keywords

[No Author keywords available]

Indexed keywords

DEHYDROHOMOANCEPSENOLIDE; DRUG DERIVATIVE; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; GAMMA BUTYROLACTONE;

EID: 0034632359     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol006122d     Document Type: Article
Times cited : (85)

References (59)
  • 1
    • 0004289974 scopus 로고    scopus 로고
    • Grabley, S., Thiericke, R., Eds.; Springer: Berlin
    • For selected reviews discussing the importance of marine habitats for lead discovery, see the following references and literature cited therein: (a) Drug Discovery from Nature; Grabley, S., Thiericke, R., Eds.; Springer: Berlin, 1999.
    • (1999) Drug Discovery from Nature
  • 16
    • 0042379223 scopus 로고    scopus 로고
    • note
    • The Alder-ene reaction produces two alkenes in the tether between the butenolide headgroups which must be hydrogenated en route to 1.
  • 21
    • 0001631902 scopus 로고
    • Review: Fürstner, A. Angew. Chem. 1993, 105, 171; Angew. Chem., Int. Ed. Engl. 1993, 32, 164.
    • (1993) Angew. Chem. , vol.105 , pp. 171
    • Fürstner, A.1
  • 22
    • 33748904822 scopus 로고
    • Review: Fürstner, A. Angew. Chem. 1993, 105, 171; Angew. Chem., Int. Ed. Engl. 1993, 32, 164.
    • (1993) Angew. Chem., Int. Ed. Engl. , vol.32 , pp. 164
  • 44
    • 37049120275 scopus 로고
    • Alkyne metathesis is a fairly old reaction but has found hardly any applications to advanced synthesis for a long period of time. Only recently this situation is rapidly changing, cf. ref 18. For early examples of scrambling or dimerization of simple alkynes by structurally undefined catalyst systems see: (a) Mortreux, A.; Blanchard, M. J. Chem. Soc., Chem. Commun 1974, 786.
    • (1974) J. Chem. Soc., Chem. Commun , pp. 786
    • Mortreux, A.1    Blanchard, M.2
  • 49
    • 0042379218 scopus 로고    scopus 로고
    • note
    • (f) For detailed mechanistic investigations of alkyne metathesis catalyzed by metal alkylidyne complexes see ref 16 and literature cited therein.
  • 51
    • 0038731101 scopus 로고    scopus 로고
    • (a) Fürstner, A.; Seidel, G. Angew. Chem. 1998, 110, 1758; Angew. Chem., Int. Ed. 1998, 37, 1734.
    • (1998) Angew. Chem., Int. Ed. , vol.37 , pp. 1734
  • 55
    • 0038584256 scopus 로고    scopus 로고
    • Fürstner, A.; Grela, K. Angew. Chem. 2000, 112, 1292; Angew. Chem., Int. Ed. 2000, 39, 1234.
    • (2000) Angew. Chem., Int. Ed. , vol.39 , pp. 1234
  • 57
    • 0041377274 scopus 로고    scopus 로고
    • note
    • The synthetic material was obtained as a solid (mp = 99-100°C), whereas the natural product is described to be a colorless oil. All other analytical and spectroscopic data, however, are identical to those reported in ref 7, cf. Supporting Information.
  • 58
    • 0030983374 scopus 로고    scopus 로고
    • For syntheses of bioactive bola-form resorcinol derivatives, see: Fürstner, A.; Seidel, G. J. Org. Chem. 1997, 62, 2332.
    • (1997) J. Org. Chem. , vol.62 , pp. 2332
    • Fürstner, A.1    Seidel, G.2
  • 59
    • 0038542691 scopus 로고    scopus 로고
    • For a discussion, see: Fürstner, A. Synlett 1999, 1523.
    • (1999) Synlett , vol.1523
    • Fürstner, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.