A most user-friendly protocol for ring closing metathesis reactions

Chemical Communications

Volumn , Issue 1, 1999, Pages 95-96

  Fürstner, Alois ^a   Ackermann, Lutz ^a  

^a MAX PLANCK INSTITUT FÜR KOHLENFORSCHUNG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALKADIENE; CHLORIDE; NEON; PARA CYMENE; RUTHENIUM COMPLEX;

ARTICLE; CATALYSIS; CHEMICAL REACTION; LIGHT;

EID: 0037610332     PISSN: 13597345     EISSN: None     Source Type: Journal    
DOI: 10.1039/a808810a     Document Type: Article

References (33)

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18. A. Fürstner, M. Picquet, C. Bruneau and P. H. Dixneuf, Chem. Commun., 1998, 1315. This complex also responds to hv. cf. M. Picquet, C. Bruneau and P. H. Dixneuf, Chem. Commun., 1998, 2249.
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24. Constant irradiation of the reaction mixture with a UV emitting quartz lamp dipped into the solution at room temperature is inappropriate, leaving 98% of the substrate unchanged after 16 h reaction time.
25. 3 (5.5 mol%) in the dark shows that 92% of the substrate (GC) is unchanged after 16 h. Note that after this period of time, the photoassisted reaction is quantitative. †
26. RCM can also be carried out in toluene at 80 °C; in this medium, however, the reactions tend to be less selective as shown by the following prototype experiment: (matrix presented)
27. For an in-depth study on the effect of substitution on RCM see: T. A. Kirkland and R. H. Grubbs, J. Org. Chem., 1997, 62, 7310.
28. A. Fürstner and T. Müller, Synlett, 1997, 1010.
29. A. Fürstner, T. Gastner and H. Weintritt, J. Org. Chem., in the press.
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