-
1
-
-
0030595340
-
FAN, a novel WD-repeat protein, couples the p55 TNF receptor to neutral sphingomyelinase
-
Adams-Klages, S., Adams, D., Wiegmann, K., Struve, S., Kolanus, W., SchneiderMergener, J., Kronke, M., 1996. FAN, a novel WD-repeat protein, couples the p55 TNF receptor to neutral sphingomyelinase. Cell 86, 937-947.
-
(1996)
Cell
, vol.86
, pp. 937-947
-
-
Adams-Klages, S.1
Adams, D.2
Wiegmann, K.3
Struve, S.4
Kolanus, W.5
Schneidermergener, J.6
Kronke, M.7
-
2
-
-
0031779350
-
Distinct adapter proteins mediate acid versus neutral sphingomyelinase activation through the p55 receptor for tumor necrosis factor
-
Adam-Klages, S., Schwandner, R., Adam, D., Kreder, D., Bernardo, K., Kronke, M., 1998. Distinct adapter proteins mediate acid versus neutral sphingomyelinase activation through the p55 receptor for tumor necrosis factor. J. Leukoc. Biol. 63, 678-682.
-
(1998)
J. Leukoc. Biol.
, vol.63
, pp. 678-682
-
-
Adam-Klages, S.1
Schwandner, R.2
Adam, D.3
Kreder, D.4
Bernardo, K.5
Kronke, M.6
-
3
-
-
0030013629
-
Ceramide signalling and the immune response
-
Ballou, L.R., Laulederkind, S.J., Rosloniec, E.F., Raghow, R., 1996. Ceramide signalling and the immune response. Biochim. Biophys. Acta 1301, 273-287.
-
(1996)
Biochim. Biophys. Acta
, vol.1301
, pp. 273-287
-
-
Ballou, L.R.1
Laulederkind, S.J.2
Rosloniec, E.F.3
Raghow, R.4
-
4
-
-
0028867688
-
Neuroendocrine ageing
-
Bjorntorp, P., 1995. Neuroendocrine ageing. J. Intern. Med. 238, 401-404.
-
(1995)
J. Intern. Med.
, vol.238
, pp. 401-404
-
-
Bjorntorp, P.1
-
5
-
-
0034199463
-
Prostate cancer prevention trials in the USA
-
Brawley, O.W., Pames, H., 2000. Prostate cancer prevention trials in the USA. Fur. J. Cancer 36, 1312-1315.
-
(2000)
Fur. J. Cancer
, vol.36
, pp. 1312-1315
-
-
Brawley, O.W.1
Pames, H.2
-
6
-
-
0032421354
-
Functions of lipid rafts in biological membranes
-
Brown, D.A., London, F., 1998. Functions of lipid rafts in biological membranes. Annu. Rev. Cell Dev. Biol. 14, 111-136.
-
(1998)
Annu. Rev. Cell Dev. Biol.
, vol.14
, pp. 111-136
-
-
Brown, D.A.1
London, F.2
-
7
-
-
0032925851
-
Food restriction reduces brain damage and improves behavioral outcome following excitotoxic and metabolic insults
-
Bruce-Keller, A.J., Umberger, G., McFall, R., Mattson, M.P., 1999. Food restriction reduces brain damage and improves behavioral outcome following excitotoxic and metabolic insults. Ann. Neurol. 45, 8-15.
-
(1999)
Ann. Neurol.
, vol.45
, pp. 8-15
-
-
Bruce-Keller, A.J.1
Umberger, G.2
McFall, R.3
Mattson, M.P.4
-
8
-
-
0031851003
-
Lack of ceramide generation in TF-1 human myeloid leukemic cells resistant to ionizing radiation
-
Bruno, A.P., Laurent, G., Averbeck, D., Demur, C., Bonnet, J., Bettaieb, A., Levade, T., Jaffrezou, J.P., 1998. Lack of ceramide generation in TF-1 human myeloid leukemic cells resistant to ionizing radiation. Cell Death Differ. 5, 172-182.
-
(1998)
Cell Death Differ.
, vol.5
, pp. 172-182
-
-
Bruno, A.P.1
Laurent, G.2
Averbeck, D.3
Demur, C.4
Bonnet, J.5
Bettaieb, A.6
Levade, T.7
Jaffrezou, J.P.8
-
9
-
-
0033870405
-
Energy restriction dilutes the changes related to dietary fat type in membrane phospholipid fatty acid composition in rats
-
Cha, M.C., Jones, P.J., 2000. Energy restriction dilutes the changes related to dietary fat type in membrane phospholipid fatty acid composition in rats. Metabolism 49, 977-983.
-
(2000)
Metabolism
, vol.49
, pp. 977-983
-
-
Cha, M.C.1
Jones, P.J.2
-
10
-
-
0031694479
-
Sphingolipids in atherosclerosis and vascular biology
-
Chatterjee, S., 1998. Sphingolipids in atherosclerosis and vascular biology. Arterioscler. Thromb. Vase. Biol. 18, 1523-1533.
-
(1998)
Arterioscler. Thromb. Vase. Biol.
, vol.18
, pp. 1523-1533
-
-
Chatterjee, S.1
-
11
-
-
0030815108
-
Decreasing the apoptotic threshold of tumor cells through protein kinase C inhibition and sphingomyelinase activation increases tumor killing by ionizing radiation
-
Chmura, S.J., Mauceri, HJ., Advani, S., Heimann, R., Beckett, M.A., Nodzenski, E., Quintans, J., Kufe, D.W., Weichselbaum, R.R., 1997. Decreasing the apoptotic threshold of tumor cells through protein kinase C inhibition and sphingomyelinase activation increases tumor killing by ionizing radiation. Cancer Res. 57, 4340-4347.
-
(1997)
Cancer Res.
, vol.57
, pp. 4340-4347
-
-
Chmura, S.J.1
Mauceri, H.J.2
Advani, S.3
Heimann, R.4
Beckett, M.A.5
Nodzenski, E.6
Quintans, J.7
Kufe, D.W.8
Weichselbaum, R.R.9
-
12
-
-
0031041448
-
Cytokine response modifier a (CrmA) inhibits ceramide formation in response to tumor necrosis factor: CrmA and Bcl-2 target distinct components in the apoptotic pathway
-
Dbaibo, G.S., Perry, D.K., Gamard, C.J., Platt, R., Poirier, G.G., Obeid, L.M., Hannun, Y.A., 1997. Cytokine response modifier A (CrmA) inhibits ceramide formation in response to tumor necrosis factor: CrmA and Bcl-2 target distinct components in the apoptotic pathway. J. Exp. Med. 185, 481-490.
-
(1997)
J. Exp. Med.
, vol.185
, pp. 481-490
-
-
Dbaibo, G.S.1
Perry, D.K.2
Gamard, C.J.3
Platt, R.4
Poirier, G.G.5
Obeid, L.M.6
Hannun, Y.A.7
-
13
-
-
0032528176
-
P53-dependent ceramide response to genotoxic stress
-
Dbaibo, G.S., Pushkareva, M.Y., Rachid, R.A., Alter, N., Smyth, M.J., Obeid, L.M., Hannun, Y.A., 1998. p53-dependent ceramide response to genotoxic stress. J. Clin. Invest. 102, 329-339.
-
(1998)
J. Clin. Invest.
, vol.102
, pp. 329-339
-
-
Dbaibo, G.S.1
Pushkareva, M.Y.2
Rachid, R.A.3
Alter, N.4
Smyth, M.J.5
Obeid, L.M.6
Hannun, Y.A.7
-
14
-
-
0027202552
-
Ceramide activates heterotrimeric protein phosphatase 2A
-
Dobrowslry, R.T., Kamibayashi, C., Mumby, M.C., Hannun, Y.A., 1993. Ceramide activates heterotrimeric protein phosphatase 2A. J. Biol. Chem. 268, 15523-15530.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 15523-15530
-
-
Dobrowslry, R.T.1
Kamibayashi, C.2
Mumby, M.C.3
Hannun, Y.A.4
-
15
-
-
0033566286
-
Dietary restriction and 2-deoxyglucose administration improve behavioral outcome and reduce degeneration of dopaminergic neurons in models of Parkinson's disease
-
Duan, W., Mattson, M.P., 1999. Dietary restriction and 2-deoxyglucose administration improve behavioral outcome and reduce degeneration of dopaminergic neurons in models of Parkinson's disease. J. Neurosci. Res. 57, 195-206.
-
(1999)
J. Neurosci. Res.
, vol.57
, pp. 195-206
-
-
Duan, W.1
Mattson, M.P.2
-
16
-
-
0030036916
-
Fumonisins, mycotoxins of increasing importance: Their nature and their effects. Pharmacol
-
Dutton, M.F., 1996. Fumonisins, mycotoxins of increasing importance: their nature and their effects. Pharmacol. Ther. 70, 137-161.
-
(1996)
Ther.
, vol.70
, pp. 137-161
-
-
Dutton, M.F.1
-
17
-
-
0030611082
-
Phospholipase A2 and its role in brain tissue
-
Farooqui, A.A., Yang, H.C., Rosenberger, T.A., Horrocks, L.A., 1997. Phospholipase A2 and its role in brain tissue. J. Neurochem. 69, 889-901.
-
(1997)
J. Neurochem.
, vol.69
, pp. 889-901
-
-
Farooqui, A.A.1
Yang, H.C.2
Rosenberger, T.A.3
Horrocks, L.A.4
-
18
-
-
0031710551
-
UVB irradiation up-regulates serine palmitoyltransferase in cultured human keratinocytes
-
Farrell, A.M., et al., 1998. UVB irradiation up-regulates serine palmitoyltransferase in cultured human keratinocytes. J. Lipid Res. 39, 2031-2038.
-
(1998)
J. Lipid Res.
, vol.39
, pp. 2031-2038
-
-
Farrell, A.M.1
-
19
-
-
0030885945
-
Mitochondrial free radical signal in ceramide-dependent apoptosis: A putative mechanism for neuronal death in Parkinson's disease
-
France-Lanord, V., Brugg, B., Michel, P.P., Agid, Y., Ruberg, M., 1997. Mitochondrial free radical signal in ceramide-dependent apoptosis: a putative mechanism for neuronal death in Parkinson's disease. J. Neurochem. 69, 1612-1621.
-
(1997)
J. Neurochem.
, vol.69
, pp. 1612-1621
-
-
France-Lanord, V.1
Brugg, B.2
Michel, P.P.3
Agid, Y.4
Ruberg, M.5
-
20
-
-
1842330849
-
Direct effect of ceramide on the mitochondrial electron transport chain leads to generation of reactive oxygen species. Role of mitochondrial glutathione
-
Garcia-Ruiz, C., Colell, A., Mari, M., Morales, A., Fernandez-Checa, J.C., 1997. Direct effect of ceramide on the mitochondrial electron transport chain leads to generation of reactive oxygen species. Role of mitochondrial glutathione. J. Biol. Chem. 272, 11369-11377.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 11369-11377
-
-
Garcia-Ruiz, C.1
Colell, A.2
Mari, M.3
Morales, A.4
Fernandez-Checa, J.C.5
-
21
-
-
0031013786
-
Ceramides induce a form of apoptosis in human acute lymphoblastic leukemia cells that is inhibited by Bcl-2, but not by CrmA
-
Geley, S., Hartmann, B.L., Kofler, R., 1997. Ceramides induce a form of apoptosis in human acute lymphoblastic leukemia cells that is inhibited by Bcl-2, but not by CrmA. FEES Lett. 400, 15-18.
-
(1997)
FEES Lett.
, vol.400
, pp. 15-18
-
-
Geley, S.1
Hartmann, B.L.2
Kofler, R.3
-
22
-
-
0026452763
-
Effects of aging on the conent, composition and synthesis of sphingomyelin in the central nervous system
-
Giusto, N.M., et al., 1992. Effects of aging on the conent, composition and synthesis of sphingomyelin in the central nervous system. Lipids 27, 835-839.
-
(1992)
Lipids
, vol.27
, pp. 835-839
-
-
Giusto, N.M.1
-
23
-
-
0030026613
-
Ceramide protects hippocampal neurons against excitotoxic and oxidative insults, and amyloid beta-peptide toxicity
-
Goodman, Y., Mattson, M.P., 1996. Ceramide protects hippocampal neurons against excitotoxic and oxidative insults, and amyloid beta-peptide toxicity. J. Neurochem. 6, 869-872.
-
(1996)
J. Neurochem.
, vol.6
, pp. 869-872
-
-
Goodman, Y.1
Mattson, M.P.2
-
24
-
-
0028806780
-
Finasteride: A clinical review
-
Gormley, G.J., 1995. Finasteride: a clinical review. Biomed. Pharmacother. 49, 319-324.
-
(1995)
Biomed. Pharmacother.
, vol.49
, pp. 319-324
-
-
Gormley, G.J.1
-
25
-
-
0030856714
-
Direct inhibition of mitochondrial respiratory chain complex II by cell-permiable ceramide
-
Gudz, T.I., et al., 1997. Direct inhibition of mitochondrial respiratory chain complex II by cell-permiable ceramide. J. Biol. Chem. 272, 24154-24158.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 24154-24158
-
-
Gudz, T.I.1
-
26
-
-
0034088054
-
Beneficial effects of dietary restriction on cerebral cortical synaptic terminals: Preservation of glucose transport and mitochondrial function after exposure to amyloid -peptide and oxidative and metabolic insults
-
Guo, Z., Ersoz, A., Butterfield, D.A., Mattson, M.P., 2000. Beneficial effects of dietary restriction on cerebral cortical synaptic terminals: preservation of glucose transport and mitochondrial function after exposure to amyloid -peptide and oxidative and metabolic insults. J. Neurochem. 75, 314-320.
-
(2000)
J. Neurochem.
, vol.75
, pp. 314-320
-
-
Guo, Z.1
Ersoz, A.2
Butterfield, D.A.3
Mattson, M.P.4
-
27
-
-
0030725895
-
Ceramide and the eukaryotic stress response
-
Hannun, Y.A., Obeid, L.M., 1997. Ceramide and the eukaryotic stress response. Biochem. Soc. Trans. 25, 1171-1175.
-
(1997)
Biochem. Soc. Trans.
, vol.25
, pp. 1171-1175
-
-
Hannun, Y.A.1
Obeid, L.M.2
-
28
-
-
0031016544
-
Ceramide induces apoptosis in PC 12 cells
-
Hartfield, P.J., Mayne, G.C., Murray, A.W., 1997. Ceramide induces apoptosis in PC 12 cells. FEBS Lett. 401, 148-152.
-
(1997)
FEBS Lett.
, vol.401
, pp. 148-152
-
-
Hartfield, P.J.1
Mayne, G.C.2
Murray, A.W.3
-
29
-
-
0029012443
-
Acid sphingomyelinase deficient mice: A model of types a and B Niemann-Pick disease
-
Horinouchi, K., Erlich, S., Perl, D.P., Ferlinz, K., Bisgaier, C.L., Sandhoff, K., Desnick, R.J., Stewart, C.L., Schuchman, E.H., 1995. Acid sphingomyelinase deficient mice: a model of types A and B Niemann-Pick disease. Nat. Gen. 10, 288-293.
-
(1995)
Nat. Gen.
, vol.10
, pp. 288-293
-
-
Horinouchi, K.1
Erlich, S.2
Perl, D.P.3
Ferlinz, K.4
Bisgaier, C.L.5
Sandhoff, K.6
Desnick, R.J.7
Stewart, C.L.8
Schuchman, E.H.9
-
30
-
-
0032534016
-
Application of exogenous ceramide to cultured rat spinal motoneurons promotes survival or death by regulation of apoptosis depending on its concentrations
-
Irie, F., Hirabayashi, Y., 1998. Application of exogenous ceramide to cultured rat spinal motoneurons promotes survival or death by regulation of apoptosis depending on its concentrations. J. Neurosci. Res. 54, 475-485.
-
(1998)
J. Neurosci. Res.
, vol.54
, pp. 475-485
-
-
Irie, F.1
Hirabayashi, Y.2
-
31
-
-
0028078720
-
Induction of apoptotic DNA damage and cell death by activation of the sphingomyelin pathway
-
Jarvis, W.D., Kolesnick, R.N., Fornari, F.A., Traylor, R.S., Gewirtz, D.A., Grant, S., 1994. Induction of apoptotic DNA damage and cell death by activation of the sphingomyelin pathway. Proc. Natl. Acad. Sci. USA 91, 73-77.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 73-77
-
-
Jarvis, W.D.1
Kolesnick, R.N.2
Fornari, F.A.3
Traylor, R.S.4
Gewirtz, D.A.5
Grant, S.6
-
32
-
-
0028070326
-
Identification of arachidonic acid as a mediator of sphingomyelin hydrolysis in response to tumor necrosis factor
-
Jayadev, S., Linardic, C.M., Hannun, T.A., 1994. Identification of arachidonic acid as a mediator of sphingomyelin hydrolysis in response to tumor necrosis factor. J. Biol. Chem. 269, 5757-5763.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 5757-5763
-
-
Jayadev, S.1
Linardic, C.M.2
Hannun, T.A.3
-
33
-
-
0030611270
-
Phospholipase A2 is necessary for tumor necrosis factor induced ceramide generation in L929 cells
-
Jayadev, S., Hayter, H.L., Andrieu, N., Gamard, C.J., Liu, B., Balu, R., Hayakawa, M., Ito, F., Hannun, Y.A., 1997. Phospholipase A2 is necessary for tumor necrosis factor induced ceramide generation in L929 cells. J. Biol. Chem. 272, 17 196-17203.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 17196-17203
-
-
Jayadev, S.1
Hayter, H.L.2
Andrieu, N.3
Gamard, C.J.4
Liu, B.5
Balu, R.6
Hayakawa, M.7
Ito, F.8
Hannun, Y.A.9
-
34
-
-
0028953260
-
Evidence that ceramide selectively inhibits protein kinase C-a translocation and modulates bradykinin activation of phospholipase D
-
Jones, M.J., Murray, A.W., 1995. Evidence that ceramide selectively inhibits protein kinase C-a translocation and modulates bradykinin activation of phospholipase D. J. Bio. Chem. 270, 5007-5013.
-
(1995)
J. Bio. Chem.
, vol.270
, pp. 5007-5013
-
-
Jones, M.J.1
Murray, A.W.2
-
35
-
-
0031898446
-
A potential role for ceramide in the regulation of mouse epidermal keratinocyte proliferation and differentiation
-
Jung, E.M., Griner, R.D., Mann-Blakeney, R., Bollag, W.B., 1998. A potential role for ceramide in the regulation of mouse epidermal keratinocyte proliferation and differentiation. J. Invest. Dermatol. 110, 318-323.
-
(1998)
J. Invest. Dermatol.
, vol.110
, pp. 318-323
-
-
Jung, E.M.1
Griner, R.D.2
Mann-Blakeney, R.3
Bollag, W.B.4
-
37
-
-
0033522399
-
Impaired neutral sphingomyelinase activation and cutaneous barrier repair in FAN-deficient mice
-
Kreder, D., Adam-Klages, S., Wiegmann, K., Scherer, G., Plitz, T., Jensen, J.M., Proksch, E., Steinmann, J., Pfeffer, K., Kronke, M., 1998. Impaired neutral sphingomyelinase activation and cutaneous barrier repair in FAN-deficient mice. EMBO J. 18, 2472-2479.
-
(1998)
EMBO J.
, vol.18
, pp. 2472-2479
-
-
Kreder, D.1
Adam-Klages, S.2
Wiegmann, K.3
Scherer, G.4
Plitz, T.5
Jensen, J.M.6
Proksch, E.7
Steinmann, J.8
Pfeffer, K.9
Kronke, M.10
-
38
-
-
0034489693
-
Dietary restriction increases survival of newly-generated neural cells and induces BDNF expression in the dentate gyrus of rats
-
Lee, J., Duan, W., Long, J.M., Ingram, D.K., Mattson, M.P., 2000. Dietary restriction increases survival of newly-generated neural cells and induces BDNF expression in the dentate gyrus of rats. J. Mol. Neurosci. 15, 99-108.
-
(2000)
J. Mol. Neurosci.
, vol.15
, pp. 99-108
-
-
Lee, J.1
Duan, W.2
Long, J.M.3
Ingram, D.K.4
Mattson, M.P.5
-
39
-
-
0022406161
-
Two types of hydrocarbon chain interdigitation in sphinomyelin bilayers
-
Levine, J.W., Thompson, T.E., Barenholz, Y., Huang, C., 1985. Two types of hydrocarbon chain interdigitation in sphinomyelin bilayers. Biochemistry 24, 6282-6286.
-
(1985)
Biochemistry
, vol.24
, pp. 6282-6286
-
-
Levine, J.W.1
Thompson, T.E.2
Barenholz, Y.3
Huang, C.4
-
40
-
-
0034578528
-
Activation of sphingolipid turnover and chronic generation of ceramide and sphingosine in liver during aging
-
Lightle, S.A., et al., 2000. Activation of sphingolipid turnover and chronic generation of ceramide and sphingosine in liver during aging. Mech. Ageing Dev. 120, 111-125.
-
(2000)
Mech. Ageing Dev.
, vol.120
, pp. 111-125
-
-
Lightle, S.A.1
-
41
-
-
0030960327
-
Inhibition of the neutral magnesium-dependent sphingomyelinase by glutathione
-
Liu, B., Hannun, Y.A., 1997. Inhibition of the neutral magnesium-dependent sphingomyelinase by glutathione. J. Biol. Chem. 272, 16281-16287.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 16281-16287
-
-
Liu, B.1
Hannun, Y.A.2
-
42
-
-
0027968517
-
Renaturation and tumor necrosis factor - A stimulation of a 97-kDa ceramide-activated protein kinase
-
Liu, J., Mathias, S., Yang, Z., Kolesnick, R.N. 1994, Renaturation and tumor necrosis factor - a stimulation of a 97-kDa ceramide-activated protein kinase, J. Biol. Chem. 269, 3047-3052.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 3047-3052
-
-
Liu, J.1
Mathias, S.2
Yang, Z.3
Kolesnick, R.N.4
-
43
-
-
0031134930
-
Sphingomyelin metabolism is developmentally regulated in rat lung
-
Longo, C.A., et al., 1997. Sphingomyelin metabolism is developmentally regulated in rat lung. Am. J. Respir. Cell Mol. Biol. 16, 605-612.
-
(1997)
Am. J. Respir. Cell Mol. Biol.
, vol.16
, pp. 605-612
-
-
Longo, C.A.1
-
44
-
-
0033911968
-
Ceramide mimics tumour necrosis factor-alpha in the induction of cell cycle arrest in endothelial cells. Induction of the tumour suppressor p53 with decrease in retinoblastoma/protein levels
-
Lopez-Marure, R., Ventura, J.L., Sanchez, L., Montano, L.F., Zentella, A., 2000. Ceramide mimics tumour necrosis factor-alpha in the induction of cell cycle arrest in endothelial cells. Induction of the tumour suppressor p53 with decrease in retinoblastoma/protein levels. Eur. J. Biochem. 267, 4325-4333.
-
(2000)
Eur. J. Biochem.
, vol.267
, pp. 4325-4333
-
-
Lopez-Marure, R.1
Ventura, J.L.2
Sanchez, L.3
Montano, L.F.4
Zentella, A.5
-
45
-
-
0032704158
-
Implication of radical oxygen species in ceramide generation, c-Jun N-terminal kinase activation and apoptosis induced by daunorubicin
-
Mansat-de Mas, V., Bezombes, C., Quillet-Mary, A., Bettaleb, A., D'orgeix, A.D., Laurent, G., Jaffrezou, J.P., 1999. Implication of radical oxygen species in ceramide generation, c-Jun N-terminal kinase activation and apoptosis induced by daunorubicin. Mol. Pharmacol. 56, 867-874.
-
(1999)
Mol. Pharmacol.
, vol.56
, pp. 867-874
-
-
Mansat-de Mas, V.1
Bezombes, C.2
Quillet-Mary, A.3
Bettaleb, A.4
D'Orgeix, A.D.5
Laurent, G.6
Jaffrezou, J.P.7
-
46
-
-
0032211769
-
Signal transduction of stress via ceramide
-
Mathias, S., Pena, L.A., Kolesnick, R.N., 1998. Signal transduction of stress via ceramide. Biochem. J. 335, 465-480.
-
(1998)
Biochem. J.
, vol.335
, pp. 465-480
-
-
Mathias, S.1
Pena, L.A.2
Kolesnick, R.N.3
-
47
-
-
0030611750
-
Activation of NF-kappaB protects hippocampal neurons against oxidative stress-induced apoptosis: Evidence for induction of manganese Superoxide dismutase and suppression of peroxynitrite production and protein tyrosine nitration
-
Mattson, M.P., Goodman, Y., Luo, H., Fu, W., Furukawa, K., 1997. Activation of NF-kappaB protects hippocampal neurons against oxidative stress-induced apoptosis: evidence for induction of manganese Superoxide dismutase and suppression of peroxynitrite production and protein tyrosine nitration. J. Neurosci. Res. 49, 681-697.
-
(1997)
J. Neurosci. Res.
, vol.49
, pp. 681-697
-
-
Mattson, M.P.1
Goodman, Y.2
Luo, H.3
Fu, W.4
Furukawa, K.5
-
48
-
-
0034329742
-
Apoptosis in neurodegenerative disorders
-
Mattson, M.P., 2000a. Apoptosis in neurodegenerative disorders. Nat. Rev. Mol. Cell Biol. 1, 120-129.
-
(2000)
Nat. Rev. Mol. Cell Biol.
, vol.1
, pp. 120-129
-
-
Mattson, M.P.1
-
49
-
-
0034672398
-
Neuroprotective signaling and the aging brain: Take away my food and let me run
-
Mattson, M.P., 2000b. Neuroprotective signaling and the aging brain: take away my food and let me run. Brain Res. 886, 47-53.
-
(2000)
Brain Res.
, vol.886
, pp. 47-53
-
-
Mattson, M.P.1
-
50
-
-
0034746288
-
NF-kappaB in neuronal plasticity and neurodegenerative disorders
-
Mattson, M.P., Camandola, S., 2001. NF-kappaB in neuronal plasticity and neurodegenerative disorders. J. Clin. Invest. 107, 247-254.
-
(2001)
J. Clin. Invest.
, vol.107
, pp. 247-254
-
-
Mattson, M.P.1
Camandola, S.2
-
51
-
-
0035149823
-
Emerging roles for telomerase in neuronal development and apoptosis
-
Mattson, M.P., Klapper, W., 2001. Emerging roles for telomerase in neuronal development and apoptosis. J. Neurosci. Res. 63, 1-9.
-
(2001)
J. Neurosci. Res.
, vol.63
, pp. 1-9
-
-
Mattson, M.P.1
Klapper, W.2
-
52
-
-
0029013314
-
Role of dietary sphingolipids and inhibitors of sphingolipid metabolism in cancer and other diseases
-
Merrill, A.H., Schmelz, E.M., Wang, E., Schroeder, J.J., Dillehay, D.L., Riley, R.T., 1995. Role of dietary sphingolipids and inhibitors of sphingolipid metabolism in cancer and other diseases. J. Nutr. 125, S1677-S1682.
-
(1995)
J. Nutr.
, vol.125
-
-
Merrill, A.H.1
Schmelz, E.M.2
Wang, E.3
Schroeder, J.J.4
Dillehay, D.L.5
Riley, R.T.6
-
53
-
-
15644367786
-
Importance of sphingolipids and inhibitors of sphingolipid metabolism as components of animal diets
-
Merrill, A.H., Schmelz, E.M., Wang, E., Dillehay, D.L., Rice, L.G., Meredith, F., Riley, R.T., 1997. Importance of sphingolipids and inhibitors of sphingolipid metabolism as components of animal diets. J. Nutr. 127, S830-S833.
-
(1997)
J. Nutr.
, vol.127
-
-
Merrill, A.H.1
Schmelz, E.M.2
Wang, E.3
Dillehay, D.L.4
Rice, L.G.5
Meredith, F.6
Riley, R.T.7
-
54
-
-
0032520898
-
Bipotential roles of ceramide in the growth of hippocampal neurons: Promotion of cell survival and dendritic outgrowth in dose- and developmental stage-dependent manners
-
Mitoma, J., et al., 1998. Bipotential roles of ceramide in the growth of hippocampal neurons: promotion of cell survival and dendritic outgrowth in dose- and developmental stage-dependent manners. J. Neurosci. Res. 51, 712-722.
-
(1998)
J. Neurosci. Res.
, vol.51
, pp. 712-722
-
-
Mitoma, J.1
-
55
-
-
0032939630
-
Ceramide potentiates, but sphingomyelin inhibits, vitamin D-induced keratinocyte differentiation: Comparison between keratinocytes and HL-60 cells
-
Pillai, S., Mahajan, M., Carlomusto, M., 1999. Ceramide potentiates, but sphingomyelin inhibits, vitamin D-induced keratinocyte differentiation: comparison between keratinocytes and HL-60 cells. Arch. Dermatol. Res. 291, 284-289.
-
(1999)
Arch. Dermatol. Res.
, vol.291
, pp. 284-289
-
-
Pillai, S.1
Mahajan, M.2
Carlomusto, M.3
-
56
-
-
0032920732
-
Ceramide triggers p53-dependent apoptosis in genetically defined fibrosarcoma tumour cells
-
Pruschy, M., Resch, H., Shi, Y.Q., Aalame, N., Glanzmann, C., Bodis, S., 1999. Ceramide triggers p53-dependent apoptosis in genetically defined fibrosarcoma tumour cells. Br. J. Cancer 80, 693-698.
-
(1999)
Br. J. Cancer
, vol.80
, pp. 693-698
-
-
Pruschy, M.1
Resch, H.2
Shi, Y.Q.3
Aalame, N.4
Glanzmann, C.5
Bodis, S.6
-
57
-
-
0033779101
-
Structure, function, and control of phosphoinositide-specific phospholipase C
-
Rebecchi, M.J., Pentyala, S.N., 2000. Structure, function, and control of phosphoinositide-specific phospholipase C. Physiol. Rev. 80, 1291-1335.
-
(2000)
Physiol. Rev.
, vol.80
, pp. 1291-1335
-
-
Rebecchi, M.J.1
Pentyala, S.N.2
-
58
-
-
0032524973
-
Altered cytokine production in the elderly
-
Rink, L., Cakman, L, Kirchner, H., 1998. Altered cytokine production in the elderly. Mech. Ageing Dev. 102, 199-209.
-
(1998)
Mech. Ageing Dev.
, vol.102
, pp. 199-209
-
-
Rink, L.1
Cakman, L.2
Kirchner, H.3
-
59
-
-
0032749349
-
Under-nutrition decreases serine palmitoyltransferase activity in developing rat hypothalamus
-
Rotta, L.N., et al. 1999, Under-nutrition decreases serine palmitoyltransferase activity in developing rat hypothalamus, Ann. Nutr. Metab. 43, 152-158.
-
(1999)
Ann. Nutr. Metab.
, vol.43
, pp. 152-158
-
-
Rotta, L.N.1
-
60
-
-
0031597895
-
Role of hormones in mammary cancer initiation and progression
-
Russo, I.H., Russo, J., 1998. Role of hormones in mammary cancer initiation and progression. J. Mammary Gland Biol. Neoplasia. 3, 49-61.
-
(1998)
J. Mammary Gland Biol. Neoplasia.
, vol.3
, pp. 49-61
-
-
Russo, I.H.1
Russo, J.2
-
61
-
-
0033575320
-
Ceramide induces Bcl-2 dephosphorylation via a mechanism involving mitochondrial PP2A
-
Ruvolo, P.P., et al., 1999. Ceramide induces Bcl-2 dephosphorylation via a mechanism involving mitochondrial PP2A. J. Biol. Chem. 274, 20296-20300.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 20296-20300
-
-
Ruvolo, P.P.1
-
62
-
-
16044364385
-
Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis
-
Santana, P., Pena, L.A., Haimovitz-Friedman, A., Martin, S., Green, D., McLoughlin, M., Cordon-Cardo, C., Schuchman, E.H., Fuks, Z., Kolesnick, R., 1996. Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis. Cell 86, 189-199.
-
(1996)
Cell
, vol.86
, pp. 189-199
-
-
Santana, P.1
Pena, L.A.2
Haimovitz-Friedman, A.3
Martin, S.4
Green, D.5
McLoughlin, M.6
Cordon-Cardo, C.7
Schuchman, E.H.8
Fuks, Z.9
Kolesnick, R.10
-
63
-
-
0028846952
-
Requirement of AP-1 for ceramide-induced apoptosis in human leukemia HL-60 cells
-
Sawai, H., Okazaki, T., Yamamoto, H., Okano, H., Takeda, Y., Tashima, M., Sawada, H., Okuma, M., Ishikura, H., Umehara, H., Domae, N., 1995. Requirement of AP-1 for ceramide-induced apoptosis in human leukemia HL-60 cells. J. Biol. Chem. 270, 27326-27331.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 27326-27331
-
-
Sawai, H.1
Okazaki, T.2
Yamamoto, H.3
Okano, H.4
Takeda, Y.5
Tashima, M.6
Sawada, H.7
Okuma, M.8
Ishikura, H.9
Umehara, H.10
Domae, N.11
-
64
-
-
0026458406
-
TNF activates NF-KB by phosphatidylcholine-specific phospholipase C-induced acidic sphingomyelin breakdown
-
Schütze, S., Potthoff, K., Machleidt, T., Berkovic, D., Wiegmann, K., Kronke, M., 1992. TNF activates NF-KB by phosphatidylcholine-specific phospholipase C-induced acidic sphingomyelin breakdown. Cell 71, 765-776.
-
(1992)
Cell
, vol.71
, pp. 765-776
-
-
Schütze, S.1
Potthoff, K.2
Machleidt, T.3
Berkovic, D.4
Wiegmann, K.5
Kronke, M.6
-
65
-
-
0033538073
-
Inhibition of receptor internalization by monodansyl cadaverine selectively blocks p55 TNF receptor death domain signaling
-
Schutze, S., Machleidt, T., Adam, D., Schwandner, R., Wiegmann, K., Kruse, M.L., Heinrich, M., Wickel, M., Kronke, M., 1999. Inhibition of receptor internalization by monodansyl cadaverine selectively blocks p55 TNF receptor death domain signaling. J. Biol Chem. 274, 10203-10212.
-
(1999)
J. Biol Chem.
, vol.274
, pp. 10203-10212
-
-
Schutze, S.1
Machleidt, T.2
Adam, D.3
Schwandner, R.4
Wiegmann, K.5
Kruse, M.L.6
Heinrich, M.7
Wickel, M.8
Kronke, M.9
-
66
-
-
0032489554
-
TNF receptor death domain-associated proteins TRADD and FADD signal activation of acid sphingomyelinase
-
Schwandner, R., Wiegmann, K., Bernardo, K., Kreder, D., Kronke, M., 1998. TNF receptor death domain-associated proteins TRADD and FADD signal activation of acid sphingomyelinase. J. Biol. Chem. 273, 5916-5922.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 5916-5922
-
-
Schwandner, R.1
Wiegmann, K.2
Bernardo, K.3
Kreder, D.4
Kronke, M.5
-
67
-
-
0033961443
-
Role of p53 family members in apoptosis
-
Sheikh, M.S., Fornace, A.J. Jr., 2000. Role of p53 family members in apoptosis. J. Cell Physiol. 182, 171-181.
-
(2000)
J. Cell Physiol.
, vol.182
, pp. 171-181
-
-
Sheikh, M.S.1
Fornace Jr., A.J.2
-
68
-
-
0029949938
-
PrICE: A downstream target for ceramide induced apoptosis and for the inhibitory action of Bcl-2
-
Smyth, M.J., Perry, D.K., Zhang, J., Poirier, G.G., Hannun, Y.A., Obeid, L.M., 1996. prICE: a downstream target for ceramide induced apoptosis and for the inhibitory action of Bcl-2. Biochem. J. 316, 25-28.
-
(1996)
Biochem. J.
, vol.316
, pp. 25-28
-
-
Smyth, M.J.1
Perry, D.K.2
Zhang, J.3
Poirier, G.G.4
Hannun, Y.A.5
Obeid, L.M.6
-
69
-
-
0026007955
-
Aging and food restriction: Effect on lipids of cerebral cortex
-
Tacconi, M.T., Lugona, L., Salmona, M., Pitsikas, N., Algeri, S., 1991. Aging and food restriction: effect on lipids of cerebral cortex. Neurobiol. Aging 12, 55-59.
-
(1991)
Neurobiol. Aging
, vol.12
, pp. 55-59
-
-
Tacconi, M.T.1
Lugona, L.2
Salmona, M.3
Pitsikas, N.4
Algeri, S.5
-
70
-
-
0034308223
-
Ceramide as a second messenger: Sticky solutions to sticky problems
-
Venkataraman, K., Futerman, A.H., 2000. Ceramide as a second messenger: sticky solutions to sticky problems. Trends Cell Biol. 10, 408-412.
-
(2000)
Trends Cell Biol.
, vol.10
, pp. 408-412
-
-
Venkataraman, K.1
Futerman, A.H.2
-
71
-
-
0030965162
-
Cell death induction by TNF: A matter of self control
-
Wallach, D., 1997. Cell death induction by TNF: a matter of self control. TIBS 22, 107-109.
-
(1997)
TIBS
, vol.22
, pp. 107-109
-
-
Wallach, D.1
-
72
-
-
0033081893
-
A typical PKC zeta is activated by ceramide, resulting in coactivation of NF-KB/JNK kinase and cell survival
-
Wang, Y.M., Seibenhener, M.L., Vandenplas, M.L., Woolen, M.W., 1999a. A typical PKC zeta is activated by ceramide, resulting in coactivation of NF-KB/JNK kinase and cell survival. J. Neurosci. Res. 55, 293-302.
-
(1999)
J. Neurosci. Res.
, vol.55
, pp. 293-302
-
-
Wang, Y.M.1
Seibenhener, M.L.2
Vandenplas, M.L.3
Woolen, M.W.4
-
73
-
-
0033571159
-
Aberrant sphingolipid signaling is involved in the resistance of prostate cancer cell lines to chemotherapy
-
Wang, X.Z., Beebe, J.R., Pwiti, L., Bielawska, A., Smyth, M.J., 1999b. Aberrant sphingolipid signaling is involved in the resistance of prostate cancer cell lines to chemotherapy. Cancer Res. 59, 5842-5848.
-
(1999)
Cancer Res.
, vol.59
, pp. 5842-5848
-
-
Wang, X.Z.1
Beebe, J.R.2
Pwiti, L.3
Bielawska, A.4
Smyth, M.J.5
-
74
-
-
0031549576
-
Seminars in medicine of the Beth Israel Deaconess Medical Center. Caloric intake and aging
-
Weindruch, R., Sohal, R.S., 1997. Seminars in medicine of the Beth Israel Deaconess Medical Center. Caloric intake and aging. New Eng. J. Med. 337, 986-994.
-
(1997)
New Eng. J. Med.
, vol.337
, pp. 986-994
-
-
Weindruch, R.1
Sohal, R.S.2
-
75
-
-
0028981358
-
Ceramide activates the stress-activated protein kinases
-
Westwick, J.K., Bielawska, A.E., Dbaibo, G., Hannun, Y.A., Brenner, D.A., 1995. Ceramide activates the stress-activated protein kinases. J. Biol. Chem. 270, 22689-22692.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 22689-22692
-
-
Westwick, J.K.1
Bielawska, A.E.2
Dbaibo, G.3
Hannun, Y.A.4
Brenner, D.A.5
-
76
-
-
0001611514
-
Dietary restriction and 2-deoxyglucose administration reduce focal ischemic brain damage and improve behavioral outcome: Evidence for a preconditioning mechanism
-
Yu, Z.F., Mattson, M.P., 1999. Dietary restriction and 2-deoxyglucose administration reduce focal ischemic brain damage and improve behavioral outcome: evidence for a preconditioning mechanism. J. Neurosci. Res. 57, 830-839.
-
(1999)
J. Neurosci. Res.
, vol.57
, pp. 830-839
-
-
Yu, Z.F.1
Mattson, M.P.2
-
77
-
-
0034488193
-
Pivotal role for acidic sphingomyelinase in cerebral ischemia-induced ceramide and cytokine production, and neuronal apoptosis
-
Yu, Z., Nikolova-Karakashian, M., Zhou, D., Cheng, G., Schuchman, E.H., Mattson, M.P., 2000. Pivotal role for acidic sphingomyelinase in cerebral ischemia-induced ceramide and cytokine production, and neuronal apoptosis. J. Mol. Neurosci. 15, 85-98.
-
(2000)
J. Mol. Neurosci.
, vol.15
, pp. 85-98
-
-
Yu, Z.1
Nikolova-Karakashian, M.2
Zhou, D.3
Cheng, G.4
Schuchman, E.H.5
Mattson, M.P.6
-
78
-
-
0343742670
-
Kinase suppressor of Ras is ceramide-activated protein kinase
-
Zhang, Y., Yan, B., Delikat, S., Bayoumy, S., Lin, X.H., Basu, S., MeGinley, M., Chn-Hui, P.Y., Ichenstein, H., Kolesnick, R., 1997. Kinase suppressor of Ras is ceramide-activated protein kinase. Cell 89, 63-72.
-
(1997)
Cell
, vol.89
, pp. 63-72
-
-
Zhang, Y.1
Yan, B.2
Delikat, S.3
Bayoumy, S.4
Lin, X.H.5
Basu, S.6
Meginley, M.7
Chn-Hui, P.Y.8
Ichenstein, H.9
Kolesnick, R.10
-
79
-
-
0033581321
-
Dietary restriction protects hippocampal neurons against the death-promoting action of a presenilin-1 mutation
-
Zhu, H., Guo, Q., Mattson, M.P., 1999. Dietary restriction protects hippocampal neurons against the death-promoting action of a presenilin-1 mutation. Brain Res. 842, 224-229.
-
(1999)
Brain Res.
, vol.842
, pp. 224-229
-
-
Zhu, H.1
Guo, Q.2
Mattson, M.P.3
|