메뉴 건너뛰기




Volumn 75, Issue 1, 2000, Pages 314-320

Beneficial effects of dietary restriction on cerebral cortical synaptic terminals: Preservation of glucose and glutamate transport and mitochondrial function after exposure to amyloid β-peptide, iron, and 3-nitropropionic acid

Author keywords

Alzheimer's disease; Apoptosis; Cerebral cortex; Glucose regulated protein; Glutamate; Heat shock protein; Huntington's disease; Iron; Mitochondria; Synaptosomes

Indexed keywords

3 NITROPROPIONIC ACID; AMYLOID BETA PROTEIN; GLUCOSE; GLUCOSE REGULATED PROTEIN; GLUTAMIC ACID; HEAT SHOCK PROTEIN; IRON;

EID: 0034088054     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2000.0750314.x     Document Type: Article
Times cited : (102)

References (59)
  • 2
    • 0031657749 scopus 로고    scopus 로고
    • Ischemic preconditioning and brain tolerance: Temporal histological and functional outcomes, protein synthesis requirement, and interleukin-1 receptor antagonist and early gene expression
    • Barone F. C., White R. F., Spera P. A., Ellison J., Currie R. W., Wang X., and Feuerstein G. Z. (1998) Ischemic preconditioning and brain tolerance: temporal histological and functional outcomes, protein synthesis requirement, and interleukin-1 receptor antagonist and early gene expression. Stroke 29, 1937-1950.
    • (1998) Stroke , vol.29 , pp. 1937-1950
    • Barone, F.C.1    White, R.F.2    Spera, P.A.3    Ellison, J.4    Currie, R.W.5    Wang, X.6    Feuerstein, G.Z.7
  • 3
    • 0028077894 scopus 로고
    • Neurochemistry and toxin models in Huntington's disease
    • Beal M. F. (1994) Neurochemistry and toxin models in Huntington's disease. Curr. Opin. Neurol. 7, 542-547.
    • (1994) Curr. Opin. Neurol. , vol.7 , pp. 542-547
    • Beal, M.F.1
  • 4
    • 0032972922 scopus 로고    scopus 로고
    • Altered calcium homeostasis and mitochondrial dysfunction in cortical synaptic compartments of presenilin-1 mutant mice
    • Begley J. G., Duan W., Chan S., Duff K., and Mattson M. P. (1999) Altered calcium homeostasis and mitochondrial dysfunction in cortical synaptic compartments of presenilin-1 mutant mice. J. Neurochem. 72, 1030-1039.
    • (1999) J. Neurochem. , vol.72 , pp. 1030-1039
    • Begley, J.G.1    Duan, W.2    Chan, S.3    Duff, K.4    Mattson, M.P.5
  • 5
    • 0032925851 scopus 로고    scopus 로고
    • Food restriction reduces brain damage and improves behavioral outcome following excitotoxic and metabolic insults
    • Bruce-Keller A. J., Umberger G., McFall R., and Mattson M. P. (1999) Food restriction reduces brain damage and improves behavioral outcome following excitotoxic and metabolic insults. Ann. Neurol. 45, 8-15.
    • (1999) Ann. Neurol. , vol.45 , pp. 8-15
    • Bruce-Keller, A.J.1    Umberger, G.2    McFall, R.3    Mattson, M.P.4
  • 6
    • 0028280865 scopus 로고
    • Oxygen radicals in focal cerebral ischemia
    • Chan P. H. (1994) Oxygen radicals in focal cerebral ischemia. Brain Pathol. 4, 59-65.
    • (1994) Brain Pathol. , vol.4 , pp. 59-65
    • Chan, P.H.1
  • 7
    • 0019861796 scopus 로고
    • Synaptosomes from rat brain: Morphology, compartmentation, and transmembrane pH and electrical gradients
    • Deutsch C., Drown C., Rafalowska U., and Silver I. A. (1981) Synaptosomes from rat brain: morphology, compartmentation, and transmembrane pH and electrical gradients. J. Neurochem. 36, 2063-2072.
    • (1981) J. Neurochem. , vol.36 , pp. 2063-2072
    • Deutsch, C.1    Drown, C.2    Rafalowska, U.3    Silver, I.A.4
  • 8
    • 0033566286 scopus 로고    scopus 로고
    • Dietary restriction and 2-deoxy-glucose administration improve behavioral outcome and reduce degeneration of dopaminergic neurons in models of Parkinson's disease
    • Duan W. and Mattson M. P. (1999) Dietary restriction and 2-deoxy-glucose administration improve behavioral outcome and reduce degeneration of dopaminergic neurons in models of Parkinson's disease. J. Neurosci. Res. 57, 195-206.
    • (1999) J. Neurosci. Res. , vol.57 , pp. 195-206
    • Duan, W.1    Mattson, M.P.2
  • 10
    • 0029872930 scopus 로고    scopus 로고
    • Caloric restriction increases the expression of heat shock protein in the gut
    • Ehrenfried J. A., Evers B. M., Chu K. U., Townsend C. M., and Thompson J. C. (1996) Caloric restriction increases the expression of heat shock protein in the gut. Ann. Surg. 223, 592-597.
    • (1996) Ann. Surg. , vol.223 , pp. 592-597
    • Ehrenfried, J.A.1    Evers, B.M.2    Chu, K.U.3    Townsend, C.M.4    Thompson, J.C.5
  • 11
    • 0030753881 scopus 로고    scopus 로고
    • Relevance of Na,K-ATPase to local extracellular potassium homeostasis and modulation of synaptic transmission
    • Gloor S. M. (1997) Relevance of Na,K-ATPase to local extracellular potassium homeostasis and modulation of synaptic transmission. FEBS Lett. 412, 1-4.
    • (1997) FEBS Lett. , vol.412 , pp. 1-4
    • Gloor, S.M.1
  • 12
    • 0028169905 scopus 로고
    • Secreted forms of beta-amyloid precursor protein protect hippocampal neurons against amyloid beta-peptide-induced oxidative injury
    • Goodman Y. and Mattson M. P. (1994) Secreted forms of beta-amyloid precursor protein protect hippocampal neurons against amyloid beta-peptide-induced oxidative injury. Exp. Neurol. 128, 1-12.
    • (1994) Exp. Neurol. , vol.128 , pp. 1-12
    • Goodman, Y.1    Mattson, M.P.2
  • 13
    • 0020665205 scopus 로고
    • Differential effects of intermittent feeding and voluntary exercise on body weight and lifespan in adult rats
    • Goodrick C. L., Ingram D. K., Reynolds M. A., Freeman J. R., and Cider N. L. (1983) Differential effects of intermittent feeding and voluntary exercise on body weight and lifespan in adult rats. J. Gerontol. 38, 36-45.
    • (1983) J. Gerontol. , vol.38 , pp. 36-45
    • Goodrick, C.L.1    Ingram, D.K.2    Reynolds, M.A.3    Freeman, J.R.4    Cider, N.L.5
  • 14
    • 0033616796 scopus 로고    scopus 로고
    • Neurotrophic factors [activity-dependent neurotrophic factor (ADNF) and basic fibroblast growth factor (bFGF)] interrupt excitotoxic neurodegenerative cascades promoted by a PS1 mutation
    • Guo Q., Sebastian L., Sopher B. L., Miller M. W., Glazner G. W., Ware C. B., Martin G. M., and Mattson M. P. (1999) Neurotrophic factors [activity-dependent neurotrophic factor (ADNF) and basic fibroblast growth factor (bFGF)] interrupt excitotoxic neurodegenerative cascades promoted by a PS1 mutation. Proc. Natl. Acad. Sci. USA 96, 4125-4130.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 4125-4130
    • Guo, Q.1    Sebastian, L.2    Sopher, B.L.3    Miller, M.W.4    Glazner, G.W.5    Ware, C.B.6    Martin, G.M.7    Mattson, M.P.8
  • 15
    • 0002639306 scopus 로고    scopus 로고
    • Neurotrophic factors protect cortical synaptic terminals against amyloid and oxidative stress-induced impairment of glucose transport, glutamate transport and mitochondrial function
    • Guo Z. H. and Mattson M. P. (2000) Neurotrophic factors protect cortical synaptic terminals against amyloid and oxidative stress-induced impairment of glucose transport, glutamate transport and mitochondrial function. Cereb. Cortex 10, 50-57.
    • (2000) Cereb. Cortex , vol.10 , pp. 50-57
    • Guo, Z.H.1    Mattson, M.P.2
  • 16
    • 0027285554 scopus 로고
    • Tissue distribution of the human GLUT3 glucose transporter
    • Haber R. S., Weinstein S. P., O'Boyle E., and Morgello S. (1993) Tissue distribution of the human GLUT3 glucose transporter. Endocrinology 132, 2538-2543.
    • (1993) Endocrinology , vol.132 , pp. 2538-2543
    • Haber, R.S.1    Weinstein, S.P.2    O'Boyle, E.3    Morgello, S.4
  • 17
    • 0029870841 scopus 로고    scopus 로고
    • Effect of caloric restriction on the expression of heat shock protein 70 and the activation of heat shock transcription factor 1
    • Heydari A. R., You S., Takahashi R., Gutsmann A., Sarge K. D., and Richardson A. (1996) Effect of caloric restriction on the expression of heat shock protein 70 and the activation of heat shock transcription factor 1. Dev. Genet. 18, 114-124.
    • (1996) Dev. Genet. , vol.18 , pp. 114-124
    • Heydari, A.R.1    You, S.2    Takahashi, R.3    Gutsmann, A.4    Sarge, K.D.5    Richardson, A.6
  • 18
    • 0023470630 scopus 로고
    • Dietary restriction: Effects on radial maze learning and lipofuscin pigment deposition in the hippocampus and frontal cortex
    • Idrobo F., Nandy K., Mostofsky D. I., Blatt L., and Nandy L. (1987) Dietary restriction: effects on radial maze learning and lipofuscin pigment deposition in the hippocampus and frontal cortex. Arch. Gerontol. Geriatr. 6, 355-362.
    • (1987) Arch. Gerontol. Geriatr. , vol.6 , pp. 355-362
    • Idrobo, F.1    Nandy, K.2    Mostofsky, D.I.3    Blatt, L.4    Nandy, L.5
  • 20
    • 0032476668 scopus 로고    scopus 로고
    • Hsp70 exerts its anti-apoptotic function downstream of caspase-3-like proteases
    • Jaattela M., Wissing D., Kokholm K., Kallunki T., and Egeblad M. (1998) Hsp70 exerts its anti-apoptotic function downstream of caspase-3-like proteases. EMBO J. 17, 6124-6134.
    • (1998) EMBO J. , vol.17 , pp. 6124-6134
    • Jaattela, M.1    Wissing, D.2    Kokholm, K.3    Kallunki, T.4    Egeblad, M.5
  • 21
    • 0032975570 scopus 로고    scopus 로고
    • The role of iron in neurodegeneration: Prospects for pharmacotherapy of Parkinson's disease
    • Jellinger K. A. (1999) The role of iron in neurodegeneration: prospects for pharmacotherapy of Parkinson's disease. Drugs Aging 14, 115-140.
    • (1999) Drugs Aging , vol.14 , pp. 115-140
    • Jellinger, K.A.1
  • 23
    • 0030966546 scopus 로고    scopus 로고
    • Impairment of glucose and glutamate transport and induction of mitochondrial oxidative stress and dysfunction in synaptosomes by amyloid-β peptide: Role of the lipid peroxidation product 4-hydroxynonenal
    • Keller J. N., Pang Z., Geddes J. W., Begley J. G., Germeyer A., Waeg G., and Mattson M. P. (1997) Impairment of glucose and glutamate transport and induction of mitochondrial oxidative stress and dysfunction in synaptosomes by amyloid-β peptide: role of the lipid peroxidation product 4-hydroxynonenal. J. Neurochem. 69, 273-284.
    • (1997) J. Neurochem. , vol.69 , pp. 273-284
    • Keller, J.N.1    Pang, Z.2    Geddes, J.W.3    Begley, J.G.4    Germeyer, A.5    Waeg, G.6    Mattson, M.P.7
  • 24
    • 17344371804 scopus 로고    scopus 로고
    • Mitochondrial MnSOD prevents neural apoptosis and reduces ischemic brain injury: Suppression of peroxynitrite production, lipid peroxidation and mitochondrial dysfunction
    • Keller J. N., Kindy M. S., Holtsberg F. W., St. Clair D., Yen H. C., Germeyer A., Steiner S. M., Bruce-Keller A. J., Hutchins J. B., and Mattson M. P. (1998) Mitochondrial MnSOD prevents neural apoptosis and reduces ischemic brain injury: suppression of peroxynitrite production, lipid peroxidation and mitochondrial dysfunction. J. Neurosci. 18, 687-697.
    • (1998) J. Neurosci. , vol.18 , pp. 687-697
    • Keller, J.N.1    Kindy, M.S.2    Holtsberg, F.W.3    St. Clair, D.4    Yen, H.C.5    Germeyer, A.6    Steiner, S.M.7    Bruce-Keller, A.J.8    Hutchins, J.B.9    Mattson, M.P.10
  • 25
    • 0022828058 scopus 로고
    • Influence of caloric intake on experimental carcinogenesis: A review
    • Kritchevsky D. and Klurfeld D. M. (1986) Influence of caloric intake on experimental carcinogenesis: a review. Adv. Exp. Med. Biol. 206, 55-68.
    • (1986) Adv. Exp. Med. Biol. , vol.206 , pp. 55-68
    • Kritchevsky, D.1    Klurfeld, D.M.2
  • 26
    • 0033168080 scopus 로고    scopus 로고
    • 2-Deoxy-D-glucose protects hippocampal neurons against excitotoxic and oxidative injury: Involvement of stress proteins
    • Lee J., Bruce-Keller A. J., Kruman I., Chan S., and Mattson M. P. (1999) 2-Deoxy-D-glucose protects hippocampal neurons against excitotoxic and oxidative injury: involvement of stress proteins. J. Neurosci. Res. 57, 48-61.
    • (1999) J. Neurosci. Res. , vol.57 , pp. 48-61
    • Lee, J.1    Bruce-Keller, A.J.2    Kruman, I.3    Chan, S.4    Mattson, M.P.5
  • 27
    • 0030051986 scopus 로고    scopus 로고
    • Dietary lipids and antioxidants in Parkinson's disease: A population-based, case-control study
    • Logroscino G., Marder K., Cote L., Tang M. X., Shea S., and Mayeux R. (1996) Dietary lipids and antioxidants in Parkinson's disease: a population-based, case-control study. Ann. Neurol. 39, 89-94.
    • (1996) Ann. Neurol. , vol.39 , pp. 89-94
    • Logroscino, G.1    Marder, K.2    Cote, L.3    Tang, M.X.4    Shea, S.5    Mayeux, R.6
  • 28
    • 0030714092 scopus 로고    scopus 로고
    • Elevated 4-hydroxynonenal in ventricular fluid in Alzheimer's disease
    • Lovell M. A., Ehmann W. D., Mattson M. P., and Markesbery W. R. (1997) Elevated 4-hydroxynonenal in ventricular fluid in Alzheimer's disease. Neurobiol. Aging 18, 457-461.
    • (1997) Neurobiol. Aging , vol.18 , pp. 457-461
    • Lovell, M.A.1    Ehmann, W.D.2    Mattson, M.P.3    Markesbery, W.R.4
  • 29
    • 0026328490 scopus 로고
    • The stress protein response in cultured neurons: Characterization and evidence for a protective role in excitotoxicity
    • Lowenstein D. H., Chan P., and Miles M. (1991) The stress protein response in cultured neurons: characterization and evidence for a protective role in excitotoxicity. Neuron 7, 1053-1060.
    • (1991) Neuron , vol.7 , pp. 1053-1060
    • Lowenstein, D.H.1    Chan, P.2    Miles, M.3
  • 32
    • 0031020993 scopus 로고    scopus 로고
    • Amyloid beta-peptide impairs glucose transport in hippocampal and cortical neurons: Involvement of membrane lipid peroxidation
    • Mark R. J., Pang Z., Geddes J. W., Uchida K., and Mattson M. P. (1997b) Amyloid beta-peptide impairs glucose transport in hippocampal and cortical neurons: involvement of membrane lipid peroxidation. J. Neurosci. 17, 1046-1054.
    • (1997) J. Neurosci. , vol.17 , pp. 1046-1054
    • Mark, R.J.1    Pang, Z.2    Geddes, J.W.3    Uchida, K.4    Mattson, M.P.5
  • 33
    • 0029811226 scopus 로고    scopus 로고
    • Deficient glutamate transport is associated with neurodegeneration in Alzheimer's disease
    • Masliah E., Alford M., DeTeresa R., Mallory M., and Hansen L. (1996) Deficient glutamate transport is associated with neurodegeneration in Alzheimer's disease. Ann. Neurol. 40, 759-766.
    • (1996) Ann. Neurol. , vol.40 , pp. 759-766
    • Masliah, E.1    Alford, M.2    DeTeresa, R.3    Mallory, M.4    Hansen, L.5
  • 34
    • 0029017262 scopus 로고
    • Transient forebrain ischemia protects against subsequent focal cerebral ischemia without changing cerebral perfusion
    • Matsushima K. and Hakim A. M. (1995) Transient forebrain ischemia protects against subsequent focal cerebral ischemia without changing cerebral perfusion. Stroke 26, 1047-1052.
    • (1995) Stroke , vol.26 , pp. 1047-1052
    • Matsushima, K.1    Hakim, A.M.2
  • 35
    • 0030779677 scopus 로고    scopus 로고
    • Cellular actions of β-amyloid precursor protein and its soluble and fibrillogenic derivatives
    • Mattson M. P. (1997) Cellular actions of β-amyloid precursor protein and its soluble and fibrillogenic derivatives. Physiol. Rev. 77, 1081-1132.
    • (1997) Physiol. Rev. , vol.77 , pp. 1081-1132
    • Mattson, M.P.1
  • 36
    • 0033215252 scopus 로고    scopus 로고
    • "Apoptotic" biochemical cascades in synaptic compartments: Roles in adaptive plasticity and neurodegenerative disorders
    • Mattson M. P. and Duan W. (1999) "Apoptotic" biochemical cascades in synaptic compartments: roles in adaptive plasticity and neurodegenerative disorders. J. Neurosci. Res. 58, 152-166.
    • (1999) J. Neurosci. Res. , vol.58 , pp. 152-166
    • Mattson, M.P.1    Duan, W.2
  • 37
    • 0030611750 scopus 로고    scopus 로고
    • Activation of NF-κB protects hippocampal neurons against oxidative stress-induced apoptosis: Evidence for induction of Mn-SOD and suppression of peroxynitrite production and protein tyrosine nitration
    • Mattson M. P., Goodman Y., Luo H., Fu W., and Furukawa K. (1997) Activation of NF-κB protects hippocampal neurons against oxidative stress-induced apoptosis: evidence for induction of Mn-SOD and suppression of peroxynitrite production and protein tyrosine nitration. J. Neurosci. Res. 49, 681-697.
    • (1997) J. Neurosci. Res. , vol.49 , pp. 681-697
    • Mattson, M.P.1    Goodman, Y.2    Luo, H.3    Fu, W.4    Furukawa, K.5
  • 38
    • 0033396991 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms underlying perturbed energy metabolism and neuronal degeneration in Alzheimer's and Parkinson's diseases
    • Mattson M. P., Pedersen W. A., Duan W., and Culmsee C. (1999) Cellular and molecular mechanisms underlying perturbed energy metabolism and neuronal degeneration in Alzheimer's and Parkinson's diseases. Ann. NY Acad Sci. 893, 154-175.
    • (1999) Ann. NY Acad Sci. , vol.893 , pp. 154-175
    • Mattson, M.P.1    Pedersen, W.A.2    Duan, W.3    Culmsee, C.4
  • 39
    • 0000755890 scopus 로고    scopus 로고
    • Reduced risk of Alzheimer's disease among individuals with low calorie intake
    • Mayeux R., Costa R., Bell K., Merchant C., Tung M. X., and Jacobs D. (1999) Reduced risk of Alzheimer's disease among individuals with low calorie intake. Neurology 59 (Suppl.), S296-S297.
    • (1999) Neurology , vol.59 , Issue.SUPPL.
    • Mayeux, R.1    Costa, R.2    Bell, K.3    Merchant, C.4    Tung, M.X.5    Jacobs, D.6
  • 40
    • 0026114522 scopus 로고
    • The two mammalian mitochondrial stress proteins, grp75 and hsp58, transiently interact with newly synthesized mitochondrial proteins
    • Mizzen L. A., Kabiling A. N., and Welch W. J. (1991) The two mammalian mitochondrial stress proteins, grp75 and hsp58, transiently interact with newly synthesized mitochondrial proteins. Cell Regul. 2, 165-179.
    • (1991) Cell Regul. , vol.2 , pp. 165-179
    • Mizzen, L.A.1    Kabiling, A.N.2    Welch, W.J.3
  • 41
    • 0030995379 scopus 로고    scopus 로고
    • Increased transcription of the astrocyte gene GFAP during middle age is attenuated by food restriction: Implications for the role of oxidative stress
    • Morgan T. E., Rozovsky I., Goldsmith S. K., Stone D. J., Yoshida T., and Finch C. E. (1997) Increased transcription of the astrocyte gene GFAP during middle age is attenuated by food restriction: implications for the role of oxidative stress. Free Radic. Biol. Med. 23, 524-528.
    • (1997) Free Radic. Biol. Med. , vol.23 , pp. 524-528
    • Morgan, T.E.1    Rozovsky, I.2    Goldsmith, S.K.3    Stone, D.J.4    Yoshida, T.5    Finch, C.E.6
  • 43
    • 0026535052 scopus 로고
    • Deterioration of spatial and nonspatial reference and working memory in aged rats: Protective effect of life-long calorie restriction
    • Pitsikas N. and Algeri S. (1992) Deterioration of spatial and nonspatial reference and working memory in aged rats: protective effect of life-long calorie restriction. Neurobiol. Aging 13, 369-373.
    • (1992) Neurobiol. Aging , vol.13 , pp. 369-373
    • Pitsikas, N.1    Algeri, S.2
  • 45
    • 0029435316 scopus 로고
    • Excitotoxicity and neurodegeneration in amyotrophic lateral sclerosis
    • Rothstein J. D. (1995) Excitotoxicity and neurodegeneration in amyotrophic lateral sclerosis. Clin. Neurosci. 3, 348-359.
    • (1995) Clin. Neurosci. , vol.3 , pp. 348-359
    • Rothstein, J.D.1
  • 46
    • 0030989545 scopus 로고    scopus 로고
    • 4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease
    • Sayre L. M., Zelasko D. A., Harris P. L. R., Perry G., Salomon R. G., and Smith M. A. (1997) 4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease. J. Neurochem. 68, 2092-2097.
    • (1997) J. Neurochem. , vol.68 , pp. 2092-2097
    • Sayre, L.M.1    Zelasko, D.A.2    Harris, P.L.R.3    Perry, G.4    Salomon, R.G.5    Smith, M.A.6
  • 47
    • 0032862658 scopus 로고    scopus 로고
    • Expression patterns and regulation of glutamate transporters in the developing and adult nervous system
    • Sims K. D. and Robinson M. B. (1999) Expression patterns and regulation of glutamate transporters in the developing and adult nervous system. Crit. Rev. Neurobiol. 13, 169-197.
    • (1999) Crit. Rev. Neurobiol. , vol.13 , pp. 169-197
    • Sims, K.D.1    Robinson, M.B.2
  • 48
    • 0030038103 scopus 로고    scopus 로고
    • Oxidative stress, caloric restriction, and aging
    • Sohal R. S. and Weindruch R. (1996) Oxidative stress, caloric restriction, and aging. Science 273, 59-63.
    • (1996) Science , vol.273 , pp. 59-63
    • Sohal, R.S.1    Weindruch, R.2
  • 49
    • 0028342438 scopus 로고
    • Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse
    • Sohal R. S., Ku H. H., Agarwal S., Forster M. J., and Lal H. (1994) Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse. Mech. Aging Dev. 74, 121-133.
    • (1994) Mech. Aging Dev. , vol.74 , pp. 121-133
    • Sohal, R.S.1    Ku, H.H.2    Agarwal, S.3    Forster, M.J.4    Lal, H.5
  • 50
    • 0030929766 scopus 로고
    • Calorie restriction inhibits the age-related dysregulation of the cytokines TNF-alpha and IL-6 in C3B10RF1 mice
    • Spaulding C. C., Walford R. L., and Effros R. B. (1987) Calorie restriction inhibits the age-related dysregulation of the cytokines TNF-alpha and IL-6 in C3B10RF1 mice. Mech. Ageing Dev. 93, 87-94.
    • (1987) Mech. Ageing Dev. , vol.93 , pp. 87-94
    • Spaulding, C.C.1    Walford, R.L.2    Effros, R.B.3
  • 51
    • 0029952943 scopus 로고    scopus 로고
    • DNA fragmentation and HSP70 protein induction in hippocampus and cortex occurs in separate neurons following permanent middle cerebral artery occlusions
    • States B. A., Honkaniemi J., Weinstein P. R., and Sharp F. R. (1996) DNA fragmentation and HSP70 protein induction in hippocampus and cortex occurs in separate neurons following permanent middle cerebral artery occlusions. J. Cereb. Blood Flow Metab. 16, 1165-1175.
    • (1996) J. Cereb. Blood Flow Metab. , vol.16 , pp. 1165-1175
    • States, B.A.1    Honkaniemi, J.2    Weinstein, P.R.3    Sharp, F.R.4
  • 52
    • 0024829444 scopus 로고
    • The effects of life-long food restriction on spatial memory in young and aged Fischer 344 rats measured in the eight-arm radial and the Morris water mazes
    • Stewart J., Mitchell J., and Kalant N. (1989) The effects of life-long food restriction on spatial memory in young and aged Fischer 344 rats measured in the eight-arm radial and the Morris water mazes. Neurobiol. Aging 10, 669-675.
    • (1989) Neurobiol. Aging , vol.10 , pp. 669-675
    • Stewart, J.1    Mitchell, J.2    Kalant, N.3
  • 53
    • 0033573767 scopus 로고    scopus 로고
    • Presence of molecular chaperones, heat shock cognate (Hsc) 70 and heat shock proteins (Hsp) 40, in the postsynaptic structures of rat brain
    • Suzuki T., Usuda N., Murata S., Nakazawa A., Ohtsuka K., and Takagi H. (1999) Presence of molecular chaperones, heat shock cognate (Hsc) 70 and heat shock proteins (Hsp) 40, in the postsynaptic structures of rat brain. Brain Res. 816, 99-110.
    • (1999) Brain Res. , vol.816 , pp. 99-110
    • Suzuki, T.1    Usuda, N.2    Murata, S.3    Nakazawa, A.4    Ohtsuka, K.5    Takagi, H.6
  • 54
    • 0022179938 scopus 로고
    • Effect of intermittent feeding on thermoregulatory abilities of young and aged C57BL/6J mice
    • Talan M. I. and Ingram D. K. (1985) Effect of intermittent feeding on thermoregulatory abilities of young and aged C57BL/6J mice. Arch. Gerontol. Geriatr. 4, 251-259.
    • (1985) Arch. Gerontol. Geriatr. , vol.4 , pp. 251-259
    • Talan, M.I.1    Ingram, D.K.2
  • 55
    • 0030033521 scopus 로고    scopus 로고
    • The beneficial effects of dietary restriction: Reduced oxidative damage and enhanced apoptosis
    • Wachsman J. T. (1996) The beneficial effects of dietary restriction: reduced oxidative damage and enhanced apoptosis. Mutat. Res. 350, 25-34.
    • (1996) Mutat. Res. , vol.350 , pp. 25-34
    • Wachsman, J.T.1
  • 57
    • 0001611514 scopus 로고    scopus 로고
    • Dietary restriction and 2-deoxy-glucose administration reduce focal ischemic brain damage and improve behavioral outcome: Evidence for a preconditioning mechanism
    • Yu Z. F. and Mattson M. P. (1999) Dietary restriction and 2-deoxy-glucose administration reduce focal ischemic brain damage and improve behavioral outcome: evidence for a preconditioning mechanism. J. Neurosci. Res. 57, 830-839.
    • (1999) J. Neurosci. Res. , vol.57 , pp. 830-839
    • Yu, Z.F.1    Mattson, M.P.2
  • 58
    • 0033015485 scopus 로고    scopus 로고
    • The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: Suppression of oxidative stress and stabilization of calcium homeostasis
    • Yu Z. F., Luo H., Fu W., and Mattson M. P. (1999) The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: suppression of oxidative stress and stabilization of calcium homeostasis. Exp. Neurol. 155, 302-314.
    • (1999) Exp. Neurol. , vol.155 , pp. 302-314
    • Yu, Z.F.1    Luo, H.2    Fu, W.3    Mattson, M.P.4
  • 59
    • 0033581321 scopus 로고    scopus 로고
    • Dietary restriction protects hippocampal neurons against the death-promoting action of a presenilin-1 mutation
    • Zhu H., Guo Q., and Mattson M. P. (1999) Dietary restriction protects hippocampal neurons against the death-promoting action of a presenilin-1 mutation. Brain Res. 842, 224-229.
    • (1999) Brain Res. , vol.842 , pp. 224-229
    • Zhu, H.1    Guo, Q.2    Mattson, M.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.